10033 R-ALL-9014945 warfarin [cytosol] R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 10033 R-ALL-9014945 warfarin [cytosol] R-BTA-9026967 https://reactome.org/PathwayBrowser/#/R-BTA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Bos taurus 10033 R-ALL-9014945 warfarin [cytosol] R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 10033 R-ALL-9014945 warfarin [cytosol] R-CFA-9026967 https://reactome.org/PathwayBrowser/#/R-CFA-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Canis familiaris 10033 R-ALL-9014945 warfarin [cytosol] R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 10033 R-ALL-9014945 warfarin [cytosol] R-DME-9026967 https://reactome.org/PathwayBrowser/#/R-DME-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Drosophila melanogaster 10033 R-ALL-9014945 warfarin [cytosol] R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 10033 R-ALL-9014945 warfarin [cytosol] R-HSA-9026967 https://reactome.org/PathwayBrowser/#/R-HSA-9026967 VKORC1 inhibitors binds VKORC1 dimer TAS Homo sapiens 10033 R-ALL-9014945 warfarin [cytosol] R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 10033 R-ALL-9014945 warfarin [cytosol] R-MMU-9026967 https://reactome.org/PathwayBrowser/#/R-MMU-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Mus musculus 10033 R-ALL-9014945 warfarin [cytosol] R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 10033 R-ALL-9014945 warfarin [cytosol] R-RNO-9026967 https://reactome.org/PathwayBrowser/#/R-RNO-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Rattus norvegicus 10033 R-ALL-9014945 warfarin [cytosol] R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 10033 R-ALL-9014945 warfarin [cytosol] R-SSC-9026967 https://reactome.org/PathwayBrowser/#/R-SSC-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Sus scrofa 10033 R-ALL-9014945 warfarin [cytosol] R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 10033 R-ALL-9014945 warfarin [cytosol] R-XTR-9026967 https://reactome.org/PathwayBrowser/#/R-XTR-9026967 VKORC1 inhibitors binds VKORC1 dimer IEA Xenopus tropicalis 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-BTA-5696424 https://reactome.org/PathwayBrowser/#/R-BTA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Bos taurus 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-CEL-5696424 https://reactome.org/PathwayBrowser/#/R-CEL-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Caenorhabditis elegans 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-CFA-5696424 https://reactome.org/PathwayBrowser/#/R-CFA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Canis familiaris 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-DDI-5696424 https://reactome.org/PathwayBrowser/#/R-DDI-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Dictyostelium discoideum 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-DME-5696424 https://reactome.org/PathwayBrowser/#/R-DME-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Drosophila melanogaster 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-DRE-5696424 https://reactome.org/PathwayBrowser/#/R-DRE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Danio rerio 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-GGA-5696424 https://reactome.org/PathwayBrowser/#/R-GGA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Gallus gallus 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-HSA-5696424 https://reactome.org/PathwayBrowser/#/R-HSA-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters TAS Homo sapiens 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-MMU-5696424 https://reactome.org/PathwayBrowser/#/R-MMU-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Mus musculus 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-RNO-5696424 https://reactome.org/PathwayBrowser/#/R-RNO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Rattus norvegicus 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-SCE-5696424 https://reactome.org/PathwayBrowser/#/R-SCE-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Saccharomyces cerevisiae 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-SPO-5696424 https://reactome.org/PathwayBrowser/#/R-SPO-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Schizosaccharomyces pombe 10036 R-ALL-5696412 arachidyl ester [endoplasmic reticulum lumen] R-XTR-5696424 https://reactome.org/PathwayBrowser/#/R-XTR-5696424 AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters IEA Xenopus tropicalis 10055 R-ALL-9611688 xamoterol [extracellular region] R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 10055 R-ALL-9611688 xamoterol [extracellular region] R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 10055 R-ALL-9611688 xamoterol [extracellular region] R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 10055 R-ALL-9611688 xamoterol [extracellular region] R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 10055 R-ALL-9611688 xamoterol [extracellular region] R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 10055 R-ALL-9611688 xamoterol [extracellular region] R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 10055 R-ALL-9611688 xamoterol [extracellular region] R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 10055 R-ALL-9611688 xamoterol [extracellular region] R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 10055 R-ALL-9611688 xamoterol [extracellular region] R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 10055 R-ALL-9611688 xamoterol [extracellular region] R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 10055 R-ALL-9611688 xamoterol [extracellular region] R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 10055 R-ALL-9611688 xamoterol [extracellular region] R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 10055 R-ALL-9611688 xamoterol [extracellular region] R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 10055 R-ALL-9611688 xamoterol [extracellular region] R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 10055 R-ALL-9611688 xamoterol [extracellular region] R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 10055 R-ALL-9611688 xamoterol [extracellular region] R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 10055 R-ALL-9611688 xamoterol [extracellular region] R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 10055 R-ALL-9611688 xamoterol [extracellular region] R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 10093 R-ALL-3296452 Yohimbine [extracellular region] R-BTA-3296233 https://reactome.org/PathwayBrowser/#/R-BTA-3296233 T2Rs bind bitter-tasting compounds IEA Bos taurus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 10093 R-ALL-9648287 yohimbine [extracellular region] R-BTA-9648268 https://reactome.org/PathwayBrowser/#/R-BTA-9648268 HTR1A binds HTR1A antagonists IEA Bos taurus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 10093 R-ALL-9648287 yohimbine [extracellular region] R-CEL-9648268 https://reactome.org/PathwayBrowser/#/R-CEL-9648268 HTR1A binds HTR1A antagonists IEA Caenorhabditis elegans 10093 R-ALL-3296452 Yohimbine [extracellular region] R-CFA-3296233 https://reactome.org/PathwayBrowser/#/R-CFA-3296233 T2Rs bind bitter-tasting compounds IEA Canis familiaris 10093 R-ALL-3296452 Yohimbine [extracellular region] R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 10093 R-ALL-3296452 Yohimbine [extracellular region] R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 10093 R-ALL-3296452 Yohimbine [extracellular region] R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 10093 R-ALL-9648287 yohimbine [extracellular region] R-CFA-9648268 https://reactome.org/PathwayBrowser/#/R-CFA-9648268 HTR1A binds HTR1A antagonists IEA Canis familiaris 10093 R-ALL-3296452 Yohimbine [extracellular region] R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 10093 R-ALL-9648287 yohimbine [extracellular region] R-DME-9648268 https://reactome.org/PathwayBrowser/#/R-DME-9648268 HTR1A binds HTR1A antagonists IEA Drosophila melanogaster 10093 R-ALL-3296452 Yohimbine [extracellular region] R-DRE-3296233 https://reactome.org/PathwayBrowser/#/R-DRE-3296233 T2Rs bind bitter-tasting compounds IEA Danio rerio 10093 R-ALL-3296452 Yohimbine [extracellular region] R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 10093 R-ALL-9648287 yohimbine [extracellular region] R-DRE-9648268 https://reactome.org/PathwayBrowser/#/R-DRE-9648268 HTR1A binds HTR1A antagonists IEA Danio rerio 10093 R-ALL-3296452 Yohimbine [extracellular region] R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 10093 R-ALL-3296452 Yohimbine [extracellular region] R-GGA-3296233 https://reactome.org/PathwayBrowser/#/R-GGA-3296233 T2Rs bind bitter-tasting compounds IEA Gallus gallus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 10093 R-ALL-9648287 yohimbine [extracellular region] R-GGA-9648268 https://reactome.org/PathwayBrowser/#/R-GGA-9648268 HTR1A binds HTR1A antagonists IEA Gallus gallus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-3296233 https://reactome.org/PathwayBrowser/#/R-HSA-3296233 T2Rs bind bitter-tasting compounds TAS Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 10093 R-ALL-9648287 yohimbine [extracellular region] R-HSA-9648268 https://reactome.org/PathwayBrowser/#/R-HSA-9648268 HTR1A binds HTR1A antagonists TAS Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 10093 R-ALL-3296452 Yohimbine [extracellular region] R-MMU-3296233 https://reactome.org/PathwayBrowser/#/R-MMU-3296233 T2Rs bind bitter-tasting compounds IEA Mus musculus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 10093 R-ALL-9648287 yohimbine [extracellular region] R-MMU-9648268 https://reactome.org/PathwayBrowser/#/R-MMU-9648268 HTR1A binds HTR1A antagonists IEA Mus musculus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-RNO-3296233 https://reactome.org/PathwayBrowser/#/R-RNO-3296233 T2Rs bind bitter-tasting compounds IEA Rattus norvegicus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 10093 R-ALL-9648287 yohimbine [extracellular region] R-RNO-9648268 https://reactome.org/PathwayBrowser/#/R-RNO-9648268 HTR1A binds HTR1A antagonists IEA Rattus norvegicus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 10093 R-ALL-3296452 Yohimbine [extracellular region] R-SSC-3296233 https://reactome.org/PathwayBrowser/#/R-SSC-3296233 T2Rs bind bitter-tasting compounds IEA Sus scrofa 10093 R-ALL-3296452 Yohimbine [extracellular region] R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 10093 R-ALL-3296452 Yohimbine [extracellular region] R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 10093 R-ALL-3296452 Yohimbine [extracellular region] R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 10093 R-ALL-3296452 Yohimbine [extracellular region] R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 10093 R-ALL-3296452 Yohimbine [extracellular region] R-XTR-3296233 https://reactome.org/PathwayBrowser/#/R-XTR-3296233 T2Rs bind bitter-tasting compounds IEA Xenopus tropicalis 10093 R-ALL-3296452 Yohimbine [extracellular region] R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 10093 R-ALL-3296452 Yohimbine [extracellular region] R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 10093 R-ALL-3296452 Yohimbine [extracellular region] R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 10093 R-ALL-9648287 yohimbine [extracellular region] R-XTR-9648268 https://reactome.org/PathwayBrowser/#/R-XTR-9648268 HTR1A binds HTR1A antagonists IEA Xenopus tropicalis 10100 R-ALL-9684613 zafirlukast [extracellular region] R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 10100 R-ALL-9684613 zafirlukast [extracellular region] R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 10100 R-ALL-9684613 zafirlukast [extracellular region] R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 10100 R-ALL-9684613 zafirlukast [extracellular region] R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 10100 R-ALL-9684613 zafirlukast [extracellular region] R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 10100 R-ALL-9684613 zafirlukast [extracellular region] R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 10100 R-ALL-9684613 zafirlukast [extracellular region] R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 10100 R-ALL-9684613 zafirlukast [extracellular region] R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 10100 R-ALL-9684613 zafirlukast [extracellular region] R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 10100 R-ALL-9684613 zafirlukast [extracellular region] R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 10100 R-ALL-9684613 zafirlukast [extracellular region] R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 10100 R-ALL-9684613 zafirlukast [extracellular region] R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 10100 R-ALL-9684613 zafirlukast [extracellular region] R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 101085 R-ALL-9707411 diclofenamide [cytosol] R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 101085 R-ALL-9707411 diclofenamide [cytosol] R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 101085 R-ALL-9707411 diclofenamide [cytosol] R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 101085 R-ALL-9707411 diclofenamide [cytosol] R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 101085 R-ALL-9707411 diclofenamide [cytosol] R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 101085 R-ALL-9707411 diclofenamide [cytosol] R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 101085 R-ALL-9707411 diclofenamide [cytosol] R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 101085 R-ALL-9707411 diclofenamide [cytosol] R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 101085 R-ALL-9707411 diclofenamide [cytosol] R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 101085 R-ALL-9707411 diclofenamide [cytosol] R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 101085 R-ALL-9707411 diclofenamide [cytosol] R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 101085 R-ALL-9707411 diclofenamide [cytosol] R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 101096 R-ALL-9707446 ethoxzolamide [cytosol] R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 10112 R-ALL-9707176 zileuton [cytosol] R-BTA-9707186 https://reactome.org/PathwayBrowser/#/R-BTA-9707186 ALOX5 binds ALOX5 inhibitors IEA Bos taurus 10112 R-ALL-9707176 zileuton [cytosol] R-CFA-9707186 https://reactome.org/PathwayBrowser/#/R-CFA-9707186 ALOX5 binds ALOX5 inhibitors IEA Canis familiaris 10112 R-ALL-9707176 zileuton [cytosol] R-DDI-9707186 https://reactome.org/PathwayBrowser/#/R-DDI-9707186 ALOX5 binds ALOX5 inhibitors IEA Dictyostelium discoideum 10112 R-ALL-9707176 zileuton [cytosol] R-GGA-9707186 https://reactome.org/PathwayBrowser/#/R-GGA-9707186 ALOX5 binds ALOX5 inhibitors IEA Gallus gallus 10112 R-ALL-9707176 zileuton [cytosol] R-HSA-9707186 https://reactome.org/PathwayBrowser/#/R-HSA-9707186 ALOX5 binds ALOX5 inhibitors TAS Homo sapiens 10112 R-ALL-9707176 zileuton [cytosol] R-MMU-9707186 https://reactome.org/PathwayBrowser/#/R-MMU-9707186 ALOX5 binds ALOX5 inhibitors IEA Mus musculus 10112 R-ALL-9707176 zileuton [cytosol] R-RNO-9707186 https://reactome.org/PathwayBrowser/#/R-RNO-9707186 ALOX5 binds ALOX5 inhibitors IEA Rattus norvegicus 10112 R-ALL-9707176 zileuton [cytosol] R-SSC-9707186 https://reactome.org/PathwayBrowser/#/R-SSC-9707186 ALOX5 binds ALOX5 inhibitors IEA Sus scrofa 10112 R-ALL-9707176 zileuton [cytosol] R-XTR-9707186 https://reactome.org/PathwayBrowser/#/R-XTR-9707186 ALOX5 binds ALOX5 inhibitors IEA Xenopus tropicalis 10119 R-ALL-9654080 ziprasidone [extracellular region] R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 10119 R-ALL-9654080 ziprasidone [extracellular region] R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 10119 R-ALL-9654080 ziprasidone [extracellular region] R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 10119 R-ALL-9654080 ziprasidone [extracellular region] R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 10119 R-ALL-9654080 ziprasidone [extracellular region] R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 10119 R-ALL-9654080 ziprasidone [extracellular region] R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 10119 R-ALL-9654080 ziprasidone [extracellular region] R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 10119 R-ALL-9654080 ziprasidone [extracellular region] R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 10119 R-ALL-9654080 ziprasidone [extracellular region] R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 10119 R-ALL-9654080 ziprasidone [extracellular region] R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 10119 R-ALL-9654080 ziprasidone [extracellular region] R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 10119 R-ALL-9654080 ziprasidone [extracellular region] R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 10119 R-ALL-9654080 ziprasidone [extracellular region] R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 10119 R-ALL-9654080 ziprasidone [extracellular region] R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 10124 R-ALL-9693412 zolmitriptan [extracellular region] R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 10127 R-ALL-9700700 zonisamide [extracellular region] R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 10127 R-ALL-9707424 zonisamide [cytosol] R-BTA-9707419 https://reactome.org/PathwayBrowser/#/R-BTA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Bos taurus 10127 R-ALL-9707424 zonisamide [cytosol] R-CEL-9707419 https://reactome.org/PathwayBrowser/#/R-CEL-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Caenorhabditis elegans 10127 R-ALL-9707424 zonisamide [cytosol] R-CFA-9707419 https://reactome.org/PathwayBrowser/#/R-CFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Canis familiaris 10127 R-ALL-9707424 zonisamide [cytosol] R-DME-9707419 https://reactome.org/PathwayBrowser/#/R-DME-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Drosophila melanogaster 10127 R-ALL-9707424 zonisamide [cytosol] R-DRE-9707419 https://reactome.org/PathwayBrowser/#/R-DRE-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Danio rerio 10127 R-ALL-9707424 zonisamide [cytosol] R-GGA-9707419 https://reactome.org/PathwayBrowser/#/R-GGA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Gallus gallus 10127 R-ALL-9700700 zonisamide [extracellular region] R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 10127 R-ALL-9707424 zonisamide [cytosol] R-HSA-9707419 https://reactome.org/PathwayBrowser/#/R-HSA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors TAS Homo sapiens 10127 R-ALL-9707424 zonisamide [cytosol] R-MMU-9707419 https://reactome.org/PathwayBrowser/#/R-MMU-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Mus musculus 10127 R-ALL-9707424 zonisamide [cytosol] R-PFA-9707419 https://reactome.org/PathwayBrowser/#/R-PFA-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Plasmodium falciparum 10127 R-ALL-9707424 zonisamide [cytosol] R-RNO-9707419 https://reactome.org/PathwayBrowser/#/R-RNO-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Rattus norvegicus 10127 R-ALL-9700700 zonisamide [extracellular region] R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 10127 R-ALL-9700700 zonisamide [extracellular region] R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 10127 R-ALL-9700700 zonisamide [extracellular region] R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 10127 R-ALL-9707424 zonisamide [cytosol] R-SSC-9707419 https://reactome.org/PathwayBrowser/#/R-SSC-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Sus scrofa 10127 R-ALL-9707424 zonisamide [cytosol] R-XTR-9707419 https://reactome.org/PathwayBrowser/#/R-XTR-9707419 CA1:Zn2+,CA2:Zn2+ bind CA inhibitors IEA Xenopus tropicalis 101278 R-ALL-9614110 diltiazem [extracellular region] R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 101278 R-ALL-9614110 diltiazem [extracellular region] R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 101278 R-ALL-9614110 diltiazem [extracellular region] R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 101278 R-ALL-9614110 diltiazem [extracellular region] R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 101278 R-ALL-9614110 diltiazem [extracellular region] R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 101278 R-ALL-9614110 diltiazem [extracellular region] R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 101278 R-ALL-9614110 diltiazem [extracellular region] R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 101278 R-ALL-9614110 diltiazem [extracellular region] R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 101278 R-ALL-9614110 diltiazem [extracellular region] R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 101278 R-ALL-9614110 diltiazem [extracellular region] R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 101381 R-ALL-9769503 aloxistatin [endocytic vesicle lumen] R-HSA-9685655 https://reactome.org/PathwayBrowser/#/R-HSA-9685655 CTSL bind CTSL inhibitors TAS Homo sapiens 101381 R-ALL-9769503 aloxistatin [endocytic vesicle lumen] R-HSA-9686710 https://reactome.org/PathwayBrowser/#/R-HSA-9686710 Cleavage of S protein into S1:S2 TAS Homo sapiens 101381 R-ALL-9769503 aloxistatin [endocytic vesicle lumen] R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 103854 R-ALL-9626131 A61603 [extracellular region] R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 103854 R-ALL-9626131 A61603 [extracellular region] R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 103854 R-ALL-9626131 A61603 [extracellular region] R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 103854 R-ALL-9626131 A61603 [extracellular region] R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 103854 R-ALL-9626131 A61603 [extracellular region] R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 103854 R-ALL-9626131 A61603 [extracellular region] R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 103854 R-ALL-9626131 A61603 [extracellular region] R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 103854 R-ALL-9626131 A61603 [extracellular region] R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 103854 R-ALL-9626131 A61603 [extracellular region] R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 103854 R-ALL-9626131 A61603 [extracellular region] R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 103854 R-ALL-9626131 A61603 [extracellular region] R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 103854 R-ALL-9626131 A61603 [extracellular region] R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 103854 R-ALL-9626131 A61603 [extracellular region] R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 103854 R-ALL-9626131 A61603 [extracellular region] R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 103854 R-ALL-9626131 A61603 [extracellular region] R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 103854 R-ALL-9626131 A61603 [extracellular region] R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 103854 R-ALL-9626131 A61603 [extracellular region] R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 103854 R-ALL-9626131 A61603 [extracellular region] R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 103854 R-ALL-9626131 A61603 [extracellular region] R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 103854 R-ALL-9626131 A61603 [extracellular region] R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 103854 R-ALL-9626131 A61603 [extracellular region] R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 103854 R-ALL-9626131 A61603 [extracellular region] R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 103932 R-ALL-9700779 dexniguldipine [extracellular region] R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 104011 R-ALL-561068 pAHP [extracellular region] R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 104011 R-ALL-561038 pAHP [cytosol] R-BTA-561041 https://reactome.org/PathwayBrowser/#/R-BTA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Bos taurus 104011 R-ALL-561068 pAHP [extracellular region] R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 104011 R-ALL-561038 pAHP [cytosol] R-CEL-561041 https://reactome.org/PathwayBrowser/#/R-CEL-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Caenorhabditis elegans 104011 R-ALL-561068 pAHP [extracellular region] R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 104011 R-ALL-561038 pAHP [cytosol] R-CFA-561041 https://reactome.org/PathwayBrowser/#/R-CFA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Canis familiaris 104011 R-ALL-561068 pAHP [extracellular region] R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 104011 R-ALL-561038 pAHP [cytosol] R-DME-561041 https://reactome.org/PathwayBrowser/#/R-DME-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Drosophila melanogaster 104011 R-ALL-561068 pAHP [extracellular region] R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 104011 R-ALL-561038 pAHP [cytosol] R-DRE-561041 https://reactome.org/PathwayBrowser/#/R-DRE-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Danio rerio 104011 R-ALL-561068 pAHP [extracellular region] R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 104011 R-ALL-561038 pAHP [cytosol] R-GGA-561041 https://reactome.org/PathwayBrowser/#/R-GGA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Gallus gallus 104011 R-ALL-561068 pAHP [extracellular region] R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 104011 R-ALL-561038 pAHP [cytosol] R-HSA-561041 https://reactome.org/PathwayBrowser/#/R-HSA-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids TAS Homo sapiens 104011 R-ALL-561068 pAHP [extracellular region] R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 104011 R-ALL-561038 pAHP [cytosol] R-MMU-561041 https://reactome.org/PathwayBrowser/#/R-MMU-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Mus musculus 104011 R-ALL-561068 pAHP [extracellular region] R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 104011 R-ALL-561038 pAHP [cytosol] R-RNO-561041 https://reactome.org/PathwayBrowser/#/R-RNO-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Rattus norvegicus 104011 R-ALL-561068 pAHP [extracellular region] R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 104011 R-ALL-561038 pAHP [cytosol] R-SSC-561041 https://reactome.org/PathwayBrowser/#/R-SSC-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Sus scrofa 104011 R-ALL-561068 pAHP [extracellular region] R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 104011 R-ALL-561038 pAHP [cytosol] R-XTR-561041 https://reactome.org/PathwayBrowser/#/R-XTR-561041 OAT1-3 transport organic anions with antiport of dicarboxylic acids IEA Xenopus tropicalis 104023 R-ALL-9684600 SR2640 [extracellular region] R-BTA-9684627 https://reactome.org/PathwayBrowser/#/R-BTA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Bos taurus 104023 R-ALL-9684600 SR2640 [extracellular region] R-BTA-9690439 https://reactome.org/PathwayBrowser/#/R-BTA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Bos taurus 104023 R-ALL-9684600 SR2640 [extracellular region] R-CEL-9684627 https://reactome.org/PathwayBrowser/#/R-CEL-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Caenorhabditis elegans 104023 R-ALL-9684600 SR2640 [extracellular region] R-CEL-9690439 https://reactome.org/PathwayBrowser/#/R-CEL-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Caenorhabditis elegans 104023 R-ALL-9684600 SR2640 [extracellular region] R-CFA-9684627 https://reactome.org/PathwayBrowser/#/R-CFA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Canis familiaris 104023 R-ALL-9684600 SR2640 [extracellular region] R-CFA-9690439 https://reactome.org/PathwayBrowser/#/R-CFA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Canis familiaris 104023 R-ALL-9684600 SR2640 [extracellular region] R-DME-9684627 https://reactome.org/PathwayBrowser/#/R-DME-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Drosophila melanogaster 104023 R-ALL-9684600 SR2640 [extracellular region] R-DME-9690439 https://reactome.org/PathwayBrowser/#/R-DME-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Drosophila melanogaster 104023 R-ALL-9684600 SR2640 [extracellular region] R-DRE-9684627 https://reactome.org/PathwayBrowser/#/R-DRE-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Danio rerio 104023 R-ALL-9684600 SR2640 [extracellular region] R-DRE-9690439 https://reactome.org/PathwayBrowser/#/R-DRE-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Danio rerio 104023 R-ALL-9684600 SR2640 [extracellular region] R-GGA-9684627 https://reactome.org/PathwayBrowser/#/R-GGA-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Gallus gallus 104023 R-ALL-9684600 SR2640 [extracellular region] R-GGA-9690439 https://reactome.org/PathwayBrowser/#/R-GGA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Gallus gallus 104023 R-ALL-9684600 SR2640 [extracellular region] R-HSA-9684627 https://reactome.org/PathwayBrowser/#/R-HSA-9684627 CYSLTR1 binds CYSLTR1 antagonists TAS Homo sapiens 104023 R-ALL-9684600 SR2640 [extracellular region] R-HSA-9690439 https://reactome.org/PathwayBrowser/#/R-HSA-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 TAS Homo sapiens 104023 R-ALL-9684600 SR2640 [extracellular region] R-MMU-9684627 https://reactome.org/PathwayBrowser/#/R-MMU-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Mus musculus 104023 R-ALL-9684600 SR2640 [extracellular region] R-MMU-9690439 https://reactome.org/PathwayBrowser/#/R-MMU-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Mus musculus 104023 R-ALL-9684600 SR2640 [extracellular region] R-RNO-9684627 https://reactome.org/PathwayBrowser/#/R-RNO-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Rattus norvegicus 104023 R-ALL-9684600 SR2640 [extracellular region] R-RNO-9690439 https://reactome.org/PathwayBrowser/#/R-RNO-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Rattus norvegicus 104023 R-ALL-9684600 SR2640 [extracellular region] R-SSC-9684627 https://reactome.org/PathwayBrowser/#/R-SSC-9684627 CYSLTR1 binds CYSLTR1 antagonists IEA Sus scrofa 104023 R-ALL-9684600 SR2640 [extracellular region] R-SSC-9690439 https://reactome.org/PathwayBrowser/#/R-SSC-9690439 CYSLTR1 binds LTC4,LTD4,LTE4 IEA Sus scrofa 10454 R-ALL-9654020 flupentixol [extracellular region] R-BTA-9654054 https://reactome.org/PathwayBrowser/#/R-BTA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Bos taurus 10454 R-ALL-9654020 flupentixol [extracellular region] R-CEL-9654054 https://reactome.org/PathwayBrowser/#/R-CEL-9654054 DRD2 antagonist drugs bind to DRD2 IEA Caenorhabditis elegans 10454 R-ALL-9654020 flupentixol [extracellular region] R-CFA-9654054 https://reactome.org/PathwayBrowser/#/R-CFA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Canis familiaris 10454 R-ALL-9654020 flupentixol [extracellular region] R-DME-9654054 https://reactome.org/PathwayBrowser/#/R-DME-9654054 DRD2 antagonist drugs bind to DRD2 IEA Drosophila melanogaster 10454 R-ALL-9654020 flupentixol [extracellular region] R-DRE-9654054 https://reactome.org/PathwayBrowser/#/R-DRE-9654054 DRD2 antagonist drugs bind to DRD2 IEA Danio rerio 10454 R-ALL-9654020 flupentixol [extracellular region] R-GGA-9654054 https://reactome.org/PathwayBrowser/#/R-GGA-9654054 DRD2 antagonist drugs bind to DRD2 IEA Gallus gallus 10454 R-ALL-9654020 flupentixol [extracellular region] R-HSA-9654054 https://reactome.org/PathwayBrowser/#/R-HSA-9654054 DRD2 antagonist drugs bind to DRD2 TAS Homo sapiens 10454 R-ALL-9654020 flupentixol [extracellular region] R-MMU-9654054 https://reactome.org/PathwayBrowser/#/R-MMU-9654054 DRD2 antagonist drugs bind to DRD2 IEA Mus musculus 10454 R-ALL-9654020 flupentixol [extracellular region] R-RNO-9654054 https://reactome.org/PathwayBrowser/#/R-RNO-9654054 DRD2 antagonist drugs bind to DRD2 IEA Rattus norvegicus 10454 R-ALL-9654020 flupentixol [extracellular region] R-SSC-9654054 https://reactome.org/PathwayBrowser/#/R-SSC-9654054 DRD2 antagonist drugs bind to DRD2 IEA Sus scrofa 104872 R-ALL-9708249 rolipram [cytosol] R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 104872 R-ALL-9708249 rolipram [cytosol] R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 104872 R-ALL-9708249 rolipram [cytosol] R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 104872 R-ALL-9708249 rolipram [cytosol] R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 104872 R-ALL-9708249 rolipram [cytosol] R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 104872 R-ALL-9708249 rolipram [cytosol] R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 104872 R-ALL-9708249 rolipram [cytosol] R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 104872 R-ALL-9708249 rolipram [cytosol] R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 104872 R-ALL-9708249 rolipram [cytosol] R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 104872 R-ALL-9708249 rolipram [cytosol] R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 104872 R-ALL-9708249 rolipram [cytosol] R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 10545 R-ALL-917828 e- [extracellular region] R-BTA-917805 https://reactome.org/PathwayBrowser/#/R-BTA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Bos taurus 10545 R-ALL-917828 e- [extracellular region] R-CEL-917805 https://reactome.org/PathwayBrowser/#/R-CEL-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Caenorhabditis elegans 10545 R-ALL-917828 e- [extracellular region] R-CFA-917805 https://reactome.org/PathwayBrowser/#/R-CFA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Canis familiaris 10545 R-ALL-917828 e- [extracellular region] R-DME-917805 https://reactome.org/PathwayBrowser/#/R-DME-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Drosophila melanogaster 10545 R-ALL-917828 e- [extracellular region] R-DRE-917805 https://reactome.org/PathwayBrowser/#/R-DRE-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Danio rerio 10545 R-ALL-917828 e- [extracellular region] R-GGA-917805 https://reactome.org/PathwayBrowser/#/R-GGA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Gallus gallus 10545 R-ALL-879326 e- [cytosol] R-HSA-1497824 https://reactome.org/PathwayBrowser/#/R-HSA-1497824 BH4 is oxidised to the BH3 radical during the eNOS catalytic cycle TAS Homo sapiens 10545 R-ALL-6783907 beta-particle [nucleoplasm] R-HSA-3785704 https://reactome.org/PathwayBrowser/#/R-HSA-3785704 DSB inducing agents induce double strand DNA breaks TAS Homo sapiens 10545 R-ALL-917828 e- [extracellular region] R-HSA-917805 https://reactome.org/PathwayBrowser/#/R-HSA-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ TAS Homo sapiens 10545 R-ALL-917828 e- [extracellular region] R-MMU-917805 https://reactome.org/PathwayBrowser/#/R-MMU-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Mus musculus 10545 R-ALL-879326 e- [cytosol] R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 10545 R-ALL-917828 e- [extracellular region] R-RNO-917805 https://reactome.org/PathwayBrowser/#/R-RNO-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Rattus norvegicus 10545 R-ALL-917828 e- [extracellular region] R-SSC-917805 https://reactome.org/PathwayBrowser/#/R-SSC-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Sus scrofa 10545 R-ALL-917828 e- [extracellular region] R-XTR-917805 https://reactome.org/PathwayBrowser/#/R-XTR-917805 CYBRD1:Heme reduces Fe3+ to Fe2+ IEA Xenopus tropicalis 10650 R-ALL-9693476 sumatriptan [extracellular region] R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 10650 R-ALL-9693476 sumatriptan [extracellular region] R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 10650 R-ALL-9693476 sumatriptan [extracellular region] R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 10650 R-ALL-9693476 sumatriptan [extracellular region] R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 10650 R-ALL-9693476 sumatriptan [extracellular region] R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 10650 R-ALL-9693476 sumatriptan [extracellular region] R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 10650 R-ALL-9693476 sumatriptan [extracellular region] R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 10650 R-ALL-9693476 sumatriptan [extracellular region] R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 10650 R-ALL-9693476 sumatriptan [extracellular region] R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 10650 R-ALL-9693476 sumatriptan [extracellular region] R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 10668 R-HSA-5696773 5' cleaved, 3' cleaved pre-tRNA (intron-containing) [nucleoplasm] R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696763 5' cleaved, 3' cleaved pre-tRNA (intronless) [nucleoplasm] R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6784544 5',3' cleaved pre-tRNA [nucleoplasm] R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696798 Cleaved pre-tRNA (intron-containing) with 3' CCA [nucleoplasm] R-HSA-5696807 https://reactome.org/PathwayBrowser/#/R-HSA-5696807 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696775 5' cleaved pre-tRNA (intron-containing) [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696767 5' cleaved pre-tRNA (intronless) [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6784537 5' cleaved pre-tRNA [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696768 pre-tRNA (intron-containing) [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696799 pre-tRNA (intronless) [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6784574 pre-tRNA [nucleoplasm] R-HSA-5696810 https://reactome.org/PathwayBrowser/#/R-HSA-5696810 RNase P cleaves the 5' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696798 Cleaved pre-tRNA (intron-containing) with 3' CCA [nucleoplasm] R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 10668 R-HSA-5696785 5' tRNA exon with 2',3' cyclic phosphate [nucleoplasm] R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 10668 R-HSA-5696797 3' tRNA exon with 5' hydroxyl [nucleoplasm] R-HSA-5696813 https://reactome.org/PathwayBrowser/#/R-HSA-5696813 TSEN complex cleaves the intron from pre-tRNA TAS Homo sapiens 10668 R-HSA-5696773 5' cleaved, 3' cleaved pre-tRNA (intron-containing) [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696763 5' cleaved, 3' cleaved pre-tRNA (intronless) [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6784544 5',3' cleaved pre-tRNA [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696775 5' cleaved pre-tRNA (intron-containing) [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696767 5' cleaved pre-tRNA (intronless) [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6784537 5' cleaved pre-tRNA [nucleoplasm] R-HSA-5696815 https://reactome.org/PathwayBrowser/#/R-HSA-5696815 ELAC2 cleaves the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-5696785 5' tRNA exon with 2',3' cyclic phosphate [nucleoplasm] R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 10668 R-HSA-5696797 3' tRNA exon with 5' hydroxyl [nucleoplasm] R-HSA-5696816 https://reactome.org/PathwayBrowser/#/R-HSA-5696816 tRNA ligase complex ligates tRNA exons TAS Homo sapiens 10668 R-HSA-6782371 unspliced tRNA(Leu)(CAA) containing C-34,48 [nucleoplasm] R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 10668 R-HSA-6782369 unspliced tRNA(Leu)(CAA) containing 5mC-34,48 [nucleoplasm] R-HSA-6782388 https://reactome.org/PathwayBrowser/#/R-HSA-6782388 NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) IEA Homo sapiens 10668 R-HSA-6786802 H strand transcript [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792999 pre-MT-TI [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792992 pre-MT-TD [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792973 pre-MT-TW [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792972 pre-MT-TF [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6793004 pre-MT-TL2 [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792970 pre-MT-TL1 [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792968 pre-MT-TR [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6793000 pre-MT-TS2 [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6793015 pre-MT-TM [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792981 pre-MT-TT [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792978 pre-MT-TH [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792987 pre-MT-TK [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792986 pre-MT-TV [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6792985 pre-MT-TG [mitochondrial matrix] R-HSA-6785722 https://reactome.org/PathwayBrowser/#/R-HSA-6785722 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript TAS Homo sapiens 10668 R-HSA-6790174 unspliced tRNA(Tyr) containing U-35 [nucleoplasm] R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 isomerizes uridine to pseudouridine in tRNAs IEA Homo sapiens 10668 R-HSA-6790176 unspliced tRNA(Tyr) containing pseudoU-35 [nucleoplasm] R-HSA-6786583 https://reactome.org/PathwayBrowser/#/R-HSA-6786583 PUS7 isomerizes uridine to pseudouridine in tRNAs IEA Homo sapiens 10668 R-HSA-6786868 L strand transcript [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6792982 pre-MT-TA [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6793013 pre-MT-TN [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6792997 pre-MT-TP [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6792962 pre-MT-TS1 [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6793020 pre-MT-TC [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6793003 pre-MT-TE [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6793001 pre-MT-TQ [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6793016 pre-MT-TY [mitochondrial matrix] R-HSA-6786854 https://reactome.org/PathwayBrowser/#/R-HSA-6786854 Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript TAS Homo sapiens 10668 R-HSA-6792982 pre-MT-TA [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793013 pre-MT-TN [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792997 pre-MT-TP [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792962 pre-MT-TS1 [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793020 pre-MT-TC [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793003 pre-MT-TE [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793001 pre-MT-TQ [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793016 pre-MT-TY [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792999 pre-MT-TI [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792992 pre-MT-TD [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792973 pre-MT-TW [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792972 pre-MT-TF [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793004 pre-MT-TL2 [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792970 pre-MT-TL1 [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792968 pre-MT-TR [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793000 pre-MT-TS2 [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6793015 pre-MT-TM [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792981 pre-MT-TT [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792978 pre-MT-TH [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792987 pre-MT-TK [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792986 pre-MT-TV [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6792985 pre-MT-TG [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6786862 5',3' cleaved pre-tRNA [mitochondrial matrix] R-HSA-6786881 https://reactome.org/PathwayBrowser/#/R-HSA-6786881 TRNT1 polymerizes CCA at the 3' end of pre-tRNA TAS Homo sapiens 10668 R-HSA-6786868 L strand transcript [mitochondrial matrix] R-HSA-9836585 https://reactome.org/PathwayBrowser/#/R-HSA-9836585 SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides TAS Homo sapiens 10668 R-HSA-6786868 L strand transcript [mitochondrial matrix] R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 10668 R-HSA-6786802 H strand transcript [mitochondrial matrix] R-HSA-9836927 https://reactome.org/PathwayBrowser/#/R-HSA-9836927 SUPV3L1 unwinds double-stranded mitochondiral RNA TAS Homo sapiens 10668 R-SCE-6790201 unspliced tRNA(Tyr) containing U35 [nucleoplasm] R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 isomerizes uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 10668 R-SCE-6790148 unspliced tRNA(Tyr) containing pseudoU-35 [nucleoplasm] R-SCE-6786558 https://reactome.org/PathwayBrowser/#/R-SCE-6786558 PUS7 isomerizes uridine to pseudouridine at nucleotide 13 of tRNA TAS Saccharomyces cerevisiae 10668 R-SCE-6790201 unspliced tRNA(Tyr) containing U35 [nucleoplasm] R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 isomerizes uridine residues to pseudouridine residues in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 10668 R-SCE-6790216 unspliced tRNA(Ile) containing U34,U36 [nucleoplasm] R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 isomerizes uridine residues to pseudouridine residues in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 10668 R-SCE-6790148 unspliced tRNA(Tyr) containing pseudoU-35 [nucleoplasm] R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 isomerizes uridine residues to pseudouridine residues in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 10668 R-SCE-6790168 unspliced tRNA(Ile) containing pseudoU34,36 [nucleoplasm] R-SCE-6790166 https://reactome.org/PathwayBrowser/#/R-SCE-6790166 PUS1 isomerizes uridine residues to pseudouridine residues in unspliced tRNA(Ile,Tyr) TAS Saccharomyces cerevisiae 10668 R-SCE-6790209 unspliced tRNA(Leu) containing C-34 [nucleoplasm] R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 10668 R-SCE-6790178 unspliced tRNA(Leu) containing 5mC-34 [nucleoplasm] R-SCE-6790189 https://reactome.org/PathwayBrowser/#/R-SCE-6790189 NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 TAS Saccharomyces cerevisiae 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-BTA-109998 https://reactome.org/PathwayBrowser/#/R-BTA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Bos taurus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-BTA-77344 https://reactome.org/PathwayBrowser/#/R-BTA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Bos taurus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-BTA-77345 https://reactome.org/PathwayBrowser/#/R-BTA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Bos taurus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CEL-77344 https://reactome.org/PathwayBrowser/#/R-CEL-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Caenorhabditis elegans 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CEL-77345 https://reactome.org/PathwayBrowser/#/R-CEL-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Caenorhabditis elegans 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CFA-109998 https://reactome.org/PathwayBrowser/#/R-CFA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Canis familiaris 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CFA-77344 https://reactome.org/PathwayBrowser/#/R-CFA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Canis familiaris 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CFA-77345 https://reactome.org/PathwayBrowser/#/R-CFA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Canis familiaris 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DDI-77344 https://reactome.org/PathwayBrowser/#/R-DDI-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Dictyostelium discoideum 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DME-109998 https://reactome.org/PathwayBrowser/#/R-DME-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Drosophila melanogaster 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DME-77344 https://reactome.org/PathwayBrowser/#/R-DME-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Drosophila melanogaster 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DME-77345 https://reactome.org/PathwayBrowser/#/R-DME-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Drosophila melanogaster 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-GGA-109998 https://reactome.org/PathwayBrowser/#/R-GGA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Gallus gallus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-GGA-77345 https://reactome.org/PathwayBrowser/#/R-GGA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Gallus gallus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-HSA-109998 https://reactome.org/PathwayBrowser/#/R-HSA-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA TAS Homo sapiens 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-HSA-77344 https://reactome.org/PathwayBrowser/#/R-HSA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA TAS Homo sapiens 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-HSA-77345 https://reactome.org/PathwayBrowser/#/R-HSA-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 TAS Homo sapiens 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-MMU-109998 https://reactome.org/PathwayBrowser/#/R-MMU-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Mus musculus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-MMU-77344 https://reactome.org/PathwayBrowser/#/R-MMU-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Mus musculus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-MMU-77345 https://reactome.org/PathwayBrowser/#/R-MMU-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Mus musculus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-RNO-109998 https://reactome.org/PathwayBrowser/#/R-RNO-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Rattus norvegicus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-RNO-77344 https://reactome.org/PathwayBrowser/#/R-RNO-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Rattus norvegicus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-RNO-77345 https://reactome.org/PathwayBrowser/#/R-RNO-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Rattus norvegicus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SSC-109998 https://reactome.org/PathwayBrowser/#/R-SSC-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Sus scrofa 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SSC-77345 https://reactome.org/PathwayBrowser/#/R-SSC-77345 Decanoyl-CoA+FAD<=>trans-Dec-2-enoyl-CoA+FADH2 IEA Sus scrofa 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-XTR-109998 https://reactome.org/PathwayBrowser/#/R-XTR-109998 Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA IEA Xenopus tropicalis 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-XTR-77344 https://reactome.org/PathwayBrowser/#/R-XTR-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Xenopus tropicalis 10723 R-ALL-77343 tdec2-CoA [mitochondrial matrix] R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 10983 R-ALL-5696461 3HBA [cytosol] R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 10983 R-ALL-5696461 3HBA [cytosol] R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 10983 R-ALL-5696461 3HBA [cytosol] R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 10983 R-ALL-5696461 3HBA [cytosol] R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 10983 R-ALL-5696461 3HBA [cytosol] R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 10983 R-ALL-5696461 3HBA [cytosol] R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 10983 R-ALL-5696461 3HBA [cytosol] R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 10983 R-ALL-5696461 3HBA [cytosol] R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 10986 R-ALL-196786 PPanK [cytosol] R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 10986 R-ALL-196786 PPanK [cytosol] R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 10986 R-ALL-196786 PPanK [cytosol] R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 10986 R-ALL-196786 PPanK [cytosol] R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 10986 R-ALL-196786 PPanK [cytosol] R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 10986 R-ALL-196786 PPanK [cytosol] R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 10986 R-ALL-196786 PPanK [cytosol] R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 10986 R-ALL-196786 PPanK [cytosol] R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 10986 R-ALL-196786 PPanK [cytosol] R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 10986 R-ALL-196786 PPanK [cytosol] R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 10986 R-ALL-196786 PPanK [cytosol] R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 10986 R-ALL-196786 PPanK [cytosol] R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 10986 R-ALL-196786 PPanK [cytosol] R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 10986 R-ALL-196786 PPanK [cytosol] R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 10986 R-ALL-196786 PPanK [cytosol] R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 10986 R-ALL-196786 PPanK [cytosol] R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 10986 R-ALL-196786 PPanK [cytosol] R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 10986 R-ALL-196786 PPanK [cytosol] R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 10986 R-ALL-196786 PPanK [cytosol] R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 10986 R-ALL-196786 PPanK [cytosol] R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 10986 R-ALL-196786 PPanK [cytosol] R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 10986 R-ALL-196786 PPanK [cytosol] R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 10986 R-ALL-196786 PPanK [cytosol] R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 10986 R-ALL-196786 PPanK [cytosol] R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 10986 R-ALL-196786 PPanK [cytosol] R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 10986 R-ALL-196786 PPanK [cytosol] R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 10986 R-ALL-196786 PPanK [cytosol] R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 10986 R-ALL-196786 PPanK [cytosol] R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 10986 R-ALL-196786 PPanK [cytosol] R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 10986 R-ALL-196786 PPanK [cytosol] R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 10986 R-ALL-196786 PPanK [cytosol] R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 10986 R-ALL-196786 PPanK [cytosol] R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 10986 R-ALL-196786 PPanK [cytosol] R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 1109 R-ALL-2164814 HMPhOH [mitochondrial matrix] R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 11230 R-ALL-5694457 1AGPC [plasma membrane] R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 11230 R-ALL-5694457 1AGPC [plasma membrane] R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 11230 R-ALL-5694457 1AGPC [plasma membrane] R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 11230 R-ALL-5694457 1AGPC [plasma membrane] R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 11230 R-ALL-5694457 1AGPC [plasma membrane] R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 11230 R-ALL-5694457 1AGPC [plasma membrane] R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 11230 R-ALL-5694457 1AGPC [plasma membrane] R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 11230 R-ALL-5694457 1AGPC [plasma membrane] R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 11230 R-ALL-5694457 1AGPC [plasma membrane] R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 11230 R-ALL-5694457 1AGPC [plasma membrane] R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 11230 R-ALL-5694457 1AGPC [plasma membrane] R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 11230 R-ALL-5694457 1AGPC [plasma membrane] R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 11230 R-ALL-5694457 1AGPC [plasma membrane] R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 114785 R-ALL-1173285 Erlotinib [cytosol] R-HSA-1220610 https://reactome.org/PathwayBrowser/#/R-HSA-1220610 Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants TAS Homo sapiens 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 116962 R-ALL-9614921 fosinoprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 116962 R-ALL-9619011 fosinoprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-BTA-114553 https://reactome.org/PathwayBrowser/#/R-BTA-114553 Activation of conventional Protein Kinase C IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-114683 https://reactome.org/PathwayBrowser/#/R-BTA-114683 Phosphorylation of Platelet Sec-1 IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-114684 https://reactome.org/PathwayBrowser/#/R-BTA-114684 Phosphorylation of Syntaxin-4 IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-1168373 https://reactome.org/PathwayBrowser/#/R-BTA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-1168635 https://reactome.org/PathwayBrowser/#/R-BTA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1482636 https://reactome.org/PathwayBrowser/#/R-BTA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1482691 https://reactome.org/PathwayBrowser/#/R-BTA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1483089 https://reactome.org/PathwayBrowser/#/R-BTA-1483089 PE is converted to PS by PTDSS2 IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 11750 R-ALL-2197635 PS [extracellular region] R-BTA-2197770 https://reactome.org/PathwayBrowser/#/R-BTA-2197770 STAB1 (FEEL-1) binds ligands IEA Bos taurus 11750 R-ALL-2197635 PS [extracellular region] R-BTA-2203479 https://reactome.org/PathwayBrowser/#/R-BTA-2203479 STAB2 (FEEL-2) binds ligands IEA Bos taurus 11750 R-ALL-2197635 PS [extracellular region] R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-BTA-2247511 https://reactome.org/PathwayBrowser/#/R-BTA-2247511 STAB2:ligand is endocytosed IEA Bos taurus 11750 R-ALL-2197635 PS [extracellular region] R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-BTA-2247512 https://reactome.org/PathwayBrowser/#/R-BTA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Bos taurus 11750 R-ALL-2197635 PS [extracellular region] R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-BTA-2247513 https://reactome.org/PathwayBrowser/#/R-BTA-2247513 STAB1:ligand is endocytosed IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-416639 https://reactome.org/PathwayBrowser/#/R-BTA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-421007 https://reactome.org/PathwayBrowser/#/R-BTA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-5138432 https://reactome.org/PathwayBrowser/#/R-BTA-5138432 DVL2 is phosphorylated by PKC IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-5696358 https://reactome.org/PathwayBrowser/#/R-BTA-5696358 TREM,CD300 binds lipids IEA Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-BTA-8867876 https://reactome.org/PathwayBrowser/#/R-BTA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-BTA-8867876 https://reactome.org/PathwayBrowser/#/R-BTA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Bos taurus 11750 R-ALL-939747 PS [external side of plasma membrane] R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 11750 R-ALL-939747 PS [external side of plasma membrane] R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-CEL-114553 https://reactome.org/PathwayBrowser/#/R-CEL-114553 Activation of conventional Protein Kinase C IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-114683 https://reactome.org/PathwayBrowser/#/R-CEL-114683 Phosphorylation of Platelet Sec-1 IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-114684 https://reactome.org/PathwayBrowser/#/R-CEL-114684 Phosphorylation of Syntaxin-4 IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-1168373 https://reactome.org/PathwayBrowser/#/R-CEL-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Caenorhabditis elegans 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CEL-1482636 https://reactome.org/PathwayBrowser/#/R-CEL-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CEL-1482691 https://reactome.org/PathwayBrowser/#/R-CEL-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Caenorhabditis elegans 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-5138432 https://reactome.org/PathwayBrowser/#/R-CEL-5138432 DVL2 is phosphorylated by PKC IEA Caenorhabditis elegans 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CEL-8867876 https://reactome.org/PathwayBrowser/#/R-CEL-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CEL-8867876 https://reactome.org/PathwayBrowser/#/R-CEL-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-939747 PS [external side of plasma membrane] R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-939747 PS [external side of plasma membrane] R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 11750 R-ALL-33625 PS [plasma membrane] R-CFA-114553 https://reactome.org/PathwayBrowser/#/R-CFA-114553 Activation of conventional Protein Kinase C IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-114683 https://reactome.org/PathwayBrowser/#/R-CFA-114683 Phosphorylation of Platelet Sec-1 IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-114684 https://reactome.org/PathwayBrowser/#/R-CFA-114684 Phosphorylation of Syntaxin-4 IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-1168373 https://reactome.org/PathwayBrowser/#/R-CFA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-1168635 https://reactome.org/PathwayBrowser/#/R-CFA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1482636 https://reactome.org/PathwayBrowser/#/R-CFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1482691 https://reactome.org/PathwayBrowser/#/R-CFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1483089 https://reactome.org/PathwayBrowser/#/R-CFA-1483089 PE is converted to PS by PTDSS2 IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2197770 https://reactome.org/PathwayBrowser/#/R-CFA-2197770 STAB1 (FEEL-1) binds ligands IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2203479 https://reactome.org/PathwayBrowser/#/R-CFA-2203479 STAB2 (FEEL-2) binds ligands IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-CFA-2247511 https://reactome.org/PathwayBrowser/#/R-CFA-2247511 STAB2:ligand is endocytosed IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-CFA-2247512 https://reactome.org/PathwayBrowser/#/R-CFA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-CFA-2247513 https://reactome.org/PathwayBrowser/#/R-CFA-2247513 STAB1:ligand is endocytosed IEA Canis familiaris 11750 R-ALL-2197635 PS [extracellular region] R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-CFA-2507854 https://reactome.org/PathwayBrowser/#/R-CFA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-416639 https://reactome.org/PathwayBrowser/#/R-CFA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-421007 https://reactome.org/PathwayBrowser/#/R-CFA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-5138432 https://reactome.org/PathwayBrowser/#/R-CFA-5138432 DVL2 is phosphorylated by PKC IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-5696358 https://reactome.org/PathwayBrowser/#/R-CFA-5696358 TREM,CD300 binds lipids IEA Canis familiaris 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-CFA-8867876 https://reactome.org/PathwayBrowser/#/R-CFA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-8867876 https://reactome.org/PathwayBrowser/#/R-CFA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-CFA-8934446 https://reactome.org/PathwayBrowser/#/R-CFA-8934446 Activated PKC phosphorylates SHC1 IEA Canis familiaris 11750 R-ALL-939747 PS [external side of plasma membrane] R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 11750 R-ALL-939747 PS [external side of plasma membrane] R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 11750 R-ALL-33625 PS [plasma membrane] R-DDI-114553 https://reactome.org/PathwayBrowser/#/R-DDI-114553 Activation of conventional Protein Kinase C IEA Dictyostelium discoideum 11750 R-ALL-33625 PS [plasma membrane] R-DDI-114683 https://reactome.org/PathwayBrowser/#/R-DDI-114683 Phosphorylation of Platelet Sec-1 IEA Dictyostelium discoideum 11750 R-ALL-33625 PS [plasma membrane] R-DDI-114684 https://reactome.org/PathwayBrowser/#/R-DDI-114684 Phosphorylation of Syntaxin-4 IEA Dictyostelium discoideum 11750 R-ALL-33625 PS [plasma membrane] R-DDI-1168373 https://reactome.org/PathwayBrowser/#/R-DDI-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Dictyostelium discoideum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DDI-1482636 https://reactome.org/PathwayBrowser/#/R-DDI-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DDI-1482691 https://reactome.org/PathwayBrowser/#/R-DDI-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Dictyostelium discoideum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DDI-1483089 https://reactome.org/PathwayBrowser/#/R-DDI-1483089 PE is converted to PS by PTDSS2 IEA Dictyostelium discoideum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DDI-8867876 https://reactome.org/PathwayBrowser/#/R-DDI-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-33625 PS [plasma membrane] R-DDI-8867876 https://reactome.org/PathwayBrowser/#/R-DDI-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-939747 PS [external side of plasma membrane] R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-939747 PS [external side of plasma membrane] R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 11750 R-ALL-33625 PS [plasma membrane] R-DME-114553 https://reactome.org/PathwayBrowser/#/R-DME-114553 Activation of conventional Protein Kinase C IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-114683 https://reactome.org/PathwayBrowser/#/R-DME-114683 Phosphorylation of Platelet Sec-1 IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-114684 https://reactome.org/PathwayBrowser/#/R-DME-114684 Phosphorylation of Syntaxin-4 IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-1168373 https://reactome.org/PathwayBrowser/#/R-DME-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Drosophila melanogaster 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DME-1482636 https://reactome.org/PathwayBrowser/#/R-DME-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DME-1482691 https://reactome.org/PathwayBrowser/#/R-DME-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Drosophila melanogaster 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-416639 https://reactome.org/PathwayBrowser/#/R-DME-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-421007 https://reactome.org/PathwayBrowser/#/R-DME-421007 Endocytosis of Ca impermeable AMPA receptors IEA Drosophila melanogaster 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DME-8867876 https://reactome.org/PathwayBrowser/#/R-DME-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-8867876 https://reactome.org/PathwayBrowser/#/R-DME-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DME-8934446 https://reactome.org/PathwayBrowser/#/R-DME-8934446 Activated PKC phosphorylates SHC1 IEA Drosophila melanogaster 11750 R-ALL-939747 PS [external side of plasma membrane] R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 11750 R-ALL-939747 PS [external side of plasma membrane] R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 11750 R-ALL-33625 PS [plasma membrane] R-DRE-114553 https://reactome.org/PathwayBrowser/#/R-DRE-114553 Activation of conventional Protein Kinase C IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-DRE-114684 https://reactome.org/PathwayBrowser/#/R-DRE-114684 Phosphorylation of Syntaxin-4 IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-DRE-1168373 https://reactome.org/PathwayBrowser/#/R-DRE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Danio rerio 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DRE-1483089 https://reactome.org/PathwayBrowser/#/R-DRE-1483089 PE is converted to PS by PTDSS2 IEA Danio rerio 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 11750 R-ALL-2197635 PS [extracellular region] R-DRE-2197770 https://reactome.org/PathwayBrowser/#/R-DRE-2197770 STAB1 (FEEL-1) binds ligands IEA Danio rerio 11750 R-ALL-2197635 PS [extracellular region] R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-DRE-2247512 https://reactome.org/PathwayBrowser/#/R-DRE-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Danio rerio 11750 R-ALL-2197635 PS [extracellular region] R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-DRE-2247513 https://reactome.org/PathwayBrowser/#/R-DRE-2247513 STAB1:ligand is endocytosed IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-DRE-5696358 https://reactome.org/PathwayBrowser/#/R-DRE-5696358 TREM,CD300 binds lipids IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 11750 R-ALL-939747 PS [external side of plasma membrane] R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 11750 R-ALL-939747 PS [external side of plasma membrane] R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 11750 R-ALL-33625 PS [plasma membrane] R-GGA-114553 https://reactome.org/PathwayBrowser/#/R-GGA-114553 Activation of conventional Protein Kinase C IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-114683 https://reactome.org/PathwayBrowser/#/R-GGA-114683 Phosphorylation of Platelet Sec-1 IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-1168373 https://reactome.org/PathwayBrowser/#/R-GGA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-1168635 https://reactome.org/PathwayBrowser/#/R-GGA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1482636 https://reactome.org/PathwayBrowser/#/R-GGA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1482691 https://reactome.org/PathwayBrowser/#/R-GGA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1483089 https://reactome.org/PathwayBrowser/#/R-GGA-1483089 PE is converted to PS by PTDSS2 IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2197770 https://reactome.org/PathwayBrowser/#/R-GGA-2197770 STAB1 (FEEL-1) binds ligands IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2203479 https://reactome.org/PathwayBrowser/#/R-GGA-2203479 STAB2 (FEEL-2) binds ligands IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-GGA-2247511 https://reactome.org/PathwayBrowser/#/R-GGA-2247511 STAB2:ligand is endocytosed IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-GGA-2247512 https://reactome.org/PathwayBrowser/#/R-GGA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-GGA-2247513 https://reactome.org/PathwayBrowser/#/R-GGA-2247513 STAB1:ligand is endocytosed IEA Gallus gallus 11750 R-ALL-2197635 PS [extracellular region] R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-GGA-2507854 https://reactome.org/PathwayBrowser/#/R-GGA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-416639 https://reactome.org/PathwayBrowser/#/R-GGA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-421007 https://reactome.org/PathwayBrowser/#/R-GGA-421007 Endocytosis of Ca impermeable AMPA receptors IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-5696358 https://reactome.org/PathwayBrowser/#/R-GGA-5696358 TREM,CD300 binds lipids IEA Gallus gallus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-GGA-8867876 https://reactome.org/PathwayBrowser/#/R-GGA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-8867876 https://reactome.org/PathwayBrowser/#/R-GGA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-GGA-8934446 https://reactome.org/PathwayBrowser/#/R-GGA-8934446 Activated PKC phosphorylates SHC1 IEA Gallus gallus 11750 R-ALL-939747 PS [external side of plasma membrane] R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 11750 R-ALL-939747 PS [external side of plasma membrane] R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 11750 R-ALL-33625 PS [plasma membrane] R-HSA-114553 https://reactome.org/PathwayBrowser/#/R-HSA-114553 Activation of conventional Protein Kinase C TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-114683 https://reactome.org/PathwayBrowser/#/R-HSA-114683 Phosphorylation of Platelet Sec-1 TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-114684 https://reactome.org/PathwayBrowser/#/R-HSA-114684 Phosphorylation of Syntaxin-4 TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-1168373 https://reactome.org/PathwayBrowser/#/R-HSA-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-1168635 https://reactome.org/PathwayBrowser/#/R-HSA-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1482636 https://reactome.org/PathwayBrowser/#/R-HSA-1482636 1-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1482691 https://reactome.org/PathwayBrowser/#/R-HSA-1482691 2-acyl LPS is acylated to PS by LPSAT TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1483089 https://reactome.org/PathwayBrowser/#/R-HSA-1483089 PE is converted to PS by PTDSS2 TAS Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1483170 https://reactome.org/PathwayBrowser/#/R-HSA-1483170 PS transports from the ER membrane to the IM membrane IEA Homo sapiens 11750 R-ALL-9025386 PS [mitochondrial inner membrane] R-HSA-1483170 https://reactome.org/PathwayBrowser/#/R-HSA-1483170 PS transports from the ER membrane to the IM membrane IEA Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 11750 R-ALL-9025386 PS [mitochondrial inner membrane] R-HSA-1483212 https://reactome.org/PathwayBrowser/#/R-HSA-1483212 PS is decarboxylated to PE by PISD IEA Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2173778 https://reactome.org/PathwayBrowser/#/R-HSA-2173778 MSR1 (SCARA1, SR-A) binds ligands IEA Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2187264 https://reactome.org/PathwayBrowser/#/R-HSA-2187264 Platelet glycoprotein IV (CD36) binds ligands IEA Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2197770 https://reactome.org/PathwayBrowser/#/R-HSA-2197770 STAB1 (FEEL-1) binds ligands TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2203479 https://reactome.org/PathwayBrowser/#/R-HSA-2203479 STAB2 (FEEL-2) binds ligands TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-HSA-2247511 https://reactome.org/PathwayBrowser/#/R-HSA-2247511 STAB2:ligand is endocytosed TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-HSA-2247512 https://reactome.org/PathwayBrowser/#/R-HSA-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-HSA-2247513 https://reactome.org/PathwayBrowser/#/R-HSA-2247513 STAB1:ligand is endocytosed TAS Homo sapiens 11750 R-ALL-2197635 PS [extracellular region] R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-HSA-2507854 https://reactome.org/PathwayBrowser/#/R-HSA-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-416639 https://reactome.org/PathwayBrowser/#/R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-421007 https://reactome.org/PathwayBrowser/#/R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-4332390 https://reactome.org/PathwayBrowser/#/R-HSA-4332390 Translocation and activation of PKC alpha in response to WNT signaling IEA Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-5138432 https://reactome.org/PathwayBrowser/#/R-HSA-5138432 DVL2 is phosphorylated by PKC TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-5696358 https://reactome.org/PathwayBrowser/#/R-HSA-5696358 TREM,CD300 binds lipids TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-751040 https://reactome.org/PathwayBrowser/#/R-HSA-751040 PKC phosphorylates G alpha (z) IEA Homo sapiens 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-HSA-8867876 https://reactome.org/PathwayBrowser/#/R-HSA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-8867876 https://reactome.org/PathwayBrowser/#/R-HSA-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-8934446 https://reactome.org/PathwayBrowser/#/R-HSA-8934446 Activated PKC phosphorylates SHC1 TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-8982703 https://reactome.org/PathwayBrowser/#/R-HSA-8982703 PKC binds active G alpha (z) IEA Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-HSA-8982709 https://reactome.org/PathwayBrowser/#/R-HSA-8982709 G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) IEA Homo sapiens 11750 R-ALL-939747 PS [external side of plasma membrane] R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 11750 R-ALL-939747 PS [external side of plasma membrane] R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 11750 R-ALL-33625 PS [plasma membrane] R-MMU-114553 https://reactome.org/PathwayBrowser/#/R-MMU-114553 Activation of conventional Protein Kinase C IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-114683 https://reactome.org/PathwayBrowser/#/R-MMU-114683 Phosphorylation of Platelet Sec-1 IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-114684 https://reactome.org/PathwayBrowser/#/R-MMU-114684 Phosphorylation of Syntaxin-4 IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-1168373 https://reactome.org/PathwayBrowser/#/R-MMU-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-1168635 https://reactome.org/PathwayBrowser/#/R-MMU-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1482636 https://reactome.org/PathwayBrowser/#/R-MMU-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1482691 https://reactome.org/PathwayBrowser/#/R-MMU-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1483089 https://reactome.org/PathwayBrowser/#/R-MMU-1483089 PE is converted to PS by PTDSS2 IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2173779 https://reactome.org/PathwayBrowser/#/R-MMU-2173779 Msr1 (Scara1) Binds Ligands TAS Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2187263 https://reactome.org/PathwayBrowser/#/R-MMU-2187263 Platelet glycoprotein 4 binds ligands TAS Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2197770 https://reactome.org/PathwayBrowser/#/R-MMU-2197770 STAB1 (FEEL-1) binds ligands IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2203479 https://reactome.org/PathwayBrowser/#/R-MMU-2203479 STAB2 (FEEL-2) binds ligands IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-MMU-2247511 https://reactome.org/PathwayBrowser/#/R-MMU-2247511 STAB2:ligand is endocytosed IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-MMU-2247512 https://reactome.org/PathwayBrowser/#/R-MMU-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-MMU-2247513 https://reactome.org/PathwayBrowser/#/R-MMU-2247513 STAB1:ligand is endocytosed IEA Mus musculus 11750 R-ALL-2197635 PS [extracellular region] R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-MMU-2507854 https://reactome.org/PathwayBrowser/#/R-MMU-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-416639 https://reactome.org/PathwayBrowser/#/R-MMU-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-421007 https://reactome.org/PathwayBrowser/#/R-MMU-421007 Endocytosis of Ca impermeable AMPA receptors IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-5138432 https://reactome.org/PathwayBrowser/#/R-MMU-5138432 DVL2 is phosphorylated by PKC IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-5696358 https://reactome.org/PathwayBrowser/#/R-MMU-5696358 TREM,CD300 binds lipids IEA Mus musculus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-MMU-8867876 https://reactome.org/PathwayBrowser/#/R-MMU-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-8867876 https://reactome.org/PathwayBrowser/#/R-MMU-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-MMU-8934446 https://reactome.org/PathwayBrowser/#/R-MMU-8934446 Activated PKC phosphorylates SHC1 IEA Mus musculus 11750 R-ALL-939747 PS [external side of plasma membrane] R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 11750 R-ALL-939747 PS [external side of plasma membrane] R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 11750 R-ALL-33625 PS [plasma membrane] R-NUL-804924 https://reactome.org/PathwayBrowser/#/R-NUL-804924 PKC (cow) phosphorylates G alpha z (rat) TAS Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-NUL-8982704 https://reactome.org/PathwayBrowser/#/R-NUL-8982704 PKC (cow) binds G alpha z (rat) TAS Bos taurus 11750 R-ALL-33625 PS [plasma membrane] R-NUL-8982712 https://reactome.org/PathwayBrowser/#/R-NUL-8982712 Gz(rat):PKC(cow) dissociates to give phosphorylated G alpha (z) TAS Bos taurus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-PFA-1482636 https://reactome.org/PathwayBrowser/#/R-PFA-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-PFA-1482691 https://reactome.org/PathwayBrowser/#/R-PFA-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Plasmodium falciparum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-PFA-1483089 https://reactome.org/PathwayBrowser/#/R-PFA-1483089 PE is converted to PS by PTDSS2 IEA Plasmodium falciparum 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 11750 R-ALL-939747 PS [external side of plasma membrane] R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 11750 R-ALL-939747 PS [external side of plasma membrane] R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 11750 R-ALL-33625 PS [plasma membrane] R-RNO-114553 https://reactome.org/PathwayBrowser/#/R-RNO-114553 Activation of conventional Protein Kinase C IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-114683 https://reactome.org/PathwayBrowser/#/R-RNO-114683 Phosphorylation of Platelet Sec-1 IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-114684 https://reactome.org/PathwayBrowser/#/R-RNO-114684 Phosphorylation of Syntaxin-4 IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-1168373 https://reactome.org/PathwayBrowser/#/R-RNO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-1168635 https://reactome.org/PathwayBrowser/#/R-RNO-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1482636 https://reactome.org/PathwayBrowser/#/R-RNO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1482691 https://reactome.org/PathwayBrowser/#/R-RNO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1483078 https://reactome.org/PathwayBrowser/#/R-RNO-1483078 PS transports from the ER membrane to the IM membrane TAS Rattus norvegicus 11750 R-ALL-9025386 PS [mitochondrial inner membrane] R-RNO-1483078 https://reactome.org/PathwayBrowser/#/R-RNO-1483078 PS transports from the ER membrane to the IM membrane TAS Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1483089 https://reactome.org/PathwayBrowser/#/R-RNO-1483089 PE is converted to PS by PTDSS2 IEA Rattus norvegicus 11750 R-ALL-9025386 PS [mitochondrial inner membrane] R-RNO-1483118 https://reactome.org/PathwayBrowser/#/R-RNO-1483118 PS is decarboxylated to PE by Pisd TAS Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 11750 R-ALL-2197635 PS [extracellular region] R-RNO-2197770 https://reactome.org/PathwayBrowser/#/R-RNO-2197770 STAB1 (FEEL-1) binds ligands IEA Rattus norvegicus 11750 R-ALL-2197635 PS [extracellular region] R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-RNO-2247512 https://reactome.org/PathwayBrowser/#/R-RNO-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Rattus norvegicus 11750 R-ALL-2197635 PS [extracellular region] R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-RNO-2247513 https://reactome.org/PathwayBrowser/#/R-RNO-2247513 STAB1:ligand is endocytosed IEA Rattus norvegicus 11750 R-ALL-2197635 PS [extracellular region] R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-RNO-2507854 https://reactome.org/PathwayBrowser/#/R-RNO-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-416639 https://reactome.org/PathwayBrowser/#/R-RNO-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-421007 https://reactome.org/PathwayBrowser/#/R-RNO-421007 Endocytosis of Ca impermeable AMPA receptors IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-5138432 https://reactome.org/PathwayBrowser/#/R-RNO-5138432 DVL2 is phosphorylated by PKC IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-5696358 https://reactome.org/PathwayBrowser/#/R-RNO-5696358 TREM,CD300 binds lipids IEA Rattus norvegicus 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-RNO-8867876 https://reactome.org/PathwayBrowser/#/R-RNO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-8867876 https://reactome.org/PathwayBrowser/#/R-RNO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-RNO-8934446 https://reactome.org/PathwayBrowser/#/R-RNO-8934446 Activated PKC phosphorylates SHC1 IEA Rattus norvegicus 11750 R-ALL-939747 PS [external side of plasma membrane] R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 11750 R-ALL-939747 PS [external side of plasma membrane] R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 11750 R-ALL-33625 PS [plasma membrane] R-SCE-114553 https://reactome.org/PathwayBrowser/#/R-SCE-114553 Activation of conventional Protein Kinase C IEA Saccharomyces cerevisiae 11750 R-ALL-33625 PS [plasma membrane] R-SCE-114683 https://reactome.org/PathwayBrowser/#/R-SCE-114683 Phosphorylation of Platelet Sec-1 IEA Saccharomyces cerevisiae 11750 R-ALL-33625 PS [plasma membrane] R-SCE-114684 https://reactome.org/PathwayBrowser/#/R-SCE-114684 Phosphorylation of Syntaxin-4 IEA Saccharomyces cerevisiae 11750 R-ALL-33625 PS [plasma membrane] R-SCE-1168373 https://reactome.org/PathwayBrowser/#/R-SCE-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Saccharomyces cerevisiae 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SCE-1482636 https://reactome.org/PathwayBrowser/#/R-SCE-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SCE-1482691 https://reactome.org/PathwayBrowser/#/R-SCE-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Saccharomyces cerevisiae 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SCE-8867876 https://reactome.org/PathwayBrowser/#/R-SCE-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-33625 PS [plasma membrane] R-SCE-8867876 https://reactome.org/PathwayBrowser/#/R-SCE-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-939747 PS [external side of plasma membrane] R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-939747 PS [external side of plasma membrane] R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 11750 R-ALL-33625 PS [plasma membrane] R-SPO-114553 https://reactome.org/PathwayBrowser/#/R-SPO-114553 Activation of conventional Protein Kinase C IEA Schizosaccharomyces pombe 11750 R-ALL-33625 PS [plasma membrane] R-SPO-114683 https://reactome.org/PathwayBrowser/#/R-SPO-114683 Phosphorylation of Platelet Sec-1 IEA Schizosaccharomyces pombe 11750 R-ALL-33625 PS [plasma membrane] R-SPO-114684 https://reactome.org/PathwayBrowser/#/R-SPO-114684 Phosphorylation of Syntaxin-4 IEA Schizosaccharomyces pombe 11750 R-ALL-33625 PS [plasma membrane] R-SPO-1168373 https://reactome.org/PathwayBrowser/#/R-SPO-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Schizosaccharomyces pombe 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SPO-1482636 https://reactome.org/PathwayBrowser/#/R-SPO-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SPO-1482691 https://reactome.org/PathwayBrowser/#/R-SPO-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Schizosaccharomyces pombe 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SPO-8867876 https://reactome.org/PathwayBrowser/#/R-SPO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-33625 PS [plasma membrane] R-SPO-8867876 https://reactome.org/PathwayBrowser/#/R-SPO-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-939747 PS [external side of plasma membrane] R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-939747 PS [external side of plasma membrane] R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 11750 R-ALL-33625 PS [plasma membrane] R-SSC-114553 https://reactome.org/PathwayBrowser/#/R-SSC-114553 Activation of conventional Protein Kinase C IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-114683 https://reactome.org/PathwayBrowser/#/R-SSC-114683 Phosphorylation of Platelet Sec-1 IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-114684 https://reactome.org/PathwayBrowser/#/R-SSC-114684 Phosphorylation of Syntaxin-4 IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1482636 https://reactome.org/PathwayBrowser/#/R-SSC-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1482691 https://reactome.org/PathwayBrowser/#/R-SSC-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1483089 https://reactome.org/PathwayBrowser/#/R-SSC-1483089 PE is converted to PS by PTDSS2 IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2197770 https://reactome.org/PathwayBrowser/#/R-SSC-2197770 STAB1 (FEEL-1) binds ligands IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2203479 https://reactome.org/PathwayBrowser/#/R-SSC-2203479 STAB2 (FEEL-2) binds ligands IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-SSC-2247511 https://reactome.org/PathwayBrowser/#/R-SSC-2247511 STAB2:ligand is endocytosed IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-SSC-2247512 https://reactome.org/PathwayBrowser/#/R-SSC-2247512 Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-SSC-2247513 https://reactome.org/PathwayBrowser/#/R-SSC-2247513 STAB1:ligand is endocytosed IEA Sus scrofa 11750 R-ALL-2197635 PS [extracellular region] R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 11750 R-ALL-2239423 PS [endocytic vesicle lumen] R-SSC-2507854 https://reactome.org/PathwayBrowser/#/R-SSC-2507854 MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-416639 https://reactome.org/PathwayBrowser/#/R-SSC-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-421007 https://reactome.org/PathwayBrowser/#/R-SSC-421007 Endocytosis of Ca impermeable AMPA receptors IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-5138432 https://reactome.org/PathwayBrowser/#/R-SSC-5138432 DVL2 is phosphorylated by PKC IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-5696358 https://reactome.org/PathwayBrowser/#/R-SSC-5696358 TREM,CD300 binds lipids IEA Sus scrofa 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-SSC-8867876 https://reactome.org/PathwayBrowser/#/R-SSC-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-8867876 https://reactome.org/PathwayBrowser/#/R-SSC-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-SSC-8934446 https://reactome.org/PathwayBrowser/#/R-SSC-8934446 Activated PKC phosphorylates SHC1 IEA Sus scrofa 11750 R-ALL-939747 PS [external side of plasma membrane] R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 11750 R-ALL-939747 PS [external side of plasma membrane] R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 11750 R-ALL-33625 PS [plasma membrane] R-XLA-4332392 https://reactome.org/PathwayBrowser/#/R-XLA-4332392 translocation of Xenopus prkca to plasma membrane TAS Xenopus laevis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-114553 https://reactome.org/PathwayBrowser/#/R-XTR-114553 Activation of conventional Protein Kinase C IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-114683 https://reactome.org/PathwayBrowser/#/R-XTR-114683 Phosphorylation of Platelet Sec-1 IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-114684 https://reactome.org/PathwayBrowser/#/R-XTR-114684 Phosphorylation of Syntaxin-4 IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-1168373 https://reactome.org/PathwayBrowser/#/R-XTR-1168373 PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-1168635 https://reactome.org/PathwayBrowser/#/R-XTR-1168635 PRKCB (PKC-beta) phosphorylates CARMA1 IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1482636 https://reactome.org/PathwayBrowser/#/R-XTR-1482636 1-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1482691 https://reactome.org/PathwayBrowser/#/R-XTR-1482691 2-acyl LPS is acylated to PS by LPSAT IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1483089 https://reactome.org/PathwayBrowser/#/R-XTR-1483089 PE is converted to PS by PTDSS2 IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-5138432 https://reactome.org/PathwayBrowser/#/R-XTR-5138432 DVL2 is phosphorylated by PKC IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-5696358 https://reactome.org/PathwayBrowser/#/R-XTR-5696358 TREM,CD300 binds lipids IEA Xenopus tropicalis 11750 R-ALL-1500646 PS [endoplasmic reticulum membrane] R-XTR-8867876 https://reactome.org/PathwayBrowser/#/R-XTR-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Xenopus tropicalis 11750 R-ALL-33625 PS [plasma membrane] R-XTR-8867876 https://reactome.org/PathwayBrowser/#/R-XTR-8867876 OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane IEA Xenopus tropicalis 11750 R-ALL-939747 PS [external side of plasma membrane] R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 11750 R-ALL-939747 PS [external side of plasma membrane] R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 11750 R-ALL-947592 PS [cytoplasmic side of plasma membrane] R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 11851 R-ALL-113584 KIV [mitochondrial matrix] R-BTA-508179 https://reactome.org/PathwayBrowser/#/R-BTA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Bos taurus 11851 R-ALL-70846 KIV [cytosol] R-BTA-508189 https://reactome.org/PathwayBrowser/#/R-BTA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Bos taurus 11851 R-ALL-70846 KIV [cytosol] R-BTA-70723 https://reactome.org/PathwayBrowser/#/R-BTA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Bos taurus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-BTA-70724 https://reactome.org/PathwayBrowser/#/R-BTA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Bos taurus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-BTA-9859148 https://reactome.org/PathwayBrowser/#/R-BTA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Bos taurus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CEL-508179 https://reactome.org/PathwayBrowser/#/R-CEL-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Caenorhabditis elegans 11851 R-ALL-70846 KIV [cytosol] R-CEL-508189 https://reactome.org/PathwayBrowser/#/R-CEL-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Caenorhabditis elegans 11851 R-ALL-70846 KIV [cytosol] R-CEL-70723 https://reactome.org/PathwayBrowser/#/R-CEL-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Caenorhabditis elegans 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CEL-70724 https://reactome.org/PathwayBrowser/#/R-CEL-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Caenorhabditis elegans 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CEL-9859148 https://reactome.org/PathwayBrowser/#/R-CEL-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Caenorhabditis elegans 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CFA-508179 https://reactome.org/PathwayBrowser/#/R-CFA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Canis familiaris 11851 R-ALL-70846 KIV [cytosol] R-CFA-508189 https://reactome.org/PathwayBrowser/#/R-CFA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Canis familiaris 11851 R-ALL-70846 KIV [cytosol] R-CFA-70723 https://reactome.org/PathwayBrowser/#/R-CFA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Canis familiaris 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CFA-70724 https://reactome.org/PathwayBrowser/#/R-CFA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Canis familiaris 11851 R-ALL-113584 KIV [mitochondrial matrix] R-CFA-9859148 https://reactome.org/PathwayBrowser/#/R-CFA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Canis familiaris 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DDI-508179 https://reactome.org/PathwayBrowser/#/R-DDI-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Dictyostelium discoideum 11851 R-ALL-70846 KIV [cytosol] R-DDI-508189 https://reactome.org/PathwayBrowser/#/R-DDI-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Dictyostelium discoideum 11851 R-ALL-70846 KIV [cytosol] R-DDI-70723 https://reactome.org/PathwayBrowser/#/R-DDI-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Dictyostelium discoideum 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DDI-70724 https://reactome.org/PathwayBrowser/#/R-DDI-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Dictyostelium discoideum 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DDI-9859148 https://reactome.org/PathwayBrowser/#/R-DDI-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Dictyostelium discoideum 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DME-508179 https://reactome.org/PathwayBrowser/#/R-DME-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Drosophila melanogaster 11851 R-ALL-70846 KIV [cytosol] R-DME-508189 https://reactome.org/PathwayBrowser/#/R-DME-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Drosophila melanogaster 11851 R-ALL-70846 KIV [cytosol] R-DME-70723 https://reactome.org/PathwayBrowser/#/R-DME-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Drosophila melanogaster 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DME-70724 https://reactome.org/PathwayBrowser/#/R-DME-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Drosophila melanogaster 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DME-9859148 https://reactome.org/PathwayBrowser/#/R-DME-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Drosophila melanogaster 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DRE-508179 https://reactome.org/PathwayBrowser/#/R-DRE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Danio rerio 11851 R-ALL-70846 KIV [cytosol] R-DRE-508189 https://reactome.org/PathwayBrowser/#/R-DRE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Danio rerio 11851 R-ALL-70846 KIV [cytosol] R-DRE-70723 https://reactome.org/PathwayBrowser/#/R-DRE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Danio rerio 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DRE-70724 https://reactome.org/PathwayBrowser/#/R-DRE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Danio rerio 11851 R-ALL-113584 KIV [mitochondrial matrix] R-DRE-9859148 https://reactome.org/PathwayBrowser/#/R-DRE-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Danio rerio 11851 R-ALL-70846 KIV [cytosol] R-GGA-508189 https://reactome.org/PathwayBrowser/#/R-GGA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Gallus gallus 11851 R-ALL-70846 KIV [cytosol] R-GGA-70723 https://reactome.org/PathwayBrowser/#/R-GGA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Gallus gallus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-GGA-9859148 https://reactome.org/PathwayBrowser/#/R-GGA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Gallus gallus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-HSA-508179 https://reactome.org/PathwayBrowser/#/R-HSA-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] TAS Homo sapiens 11851 R-ALL-70846 KIV [cytosol] R-HSA-508189 https://reactome.org/PathwayBrowser/#/R-HSA-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] TAS Homo sapiens 11851 R-ALL-70846 KIV [cytosol] R-HSA-70723 https://reactome.org/PathwayBrowser/#/R-HSA-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] TAS Homo sapiens 11851 R-ALL-113584 KIV [mitochondrial matrix] R-HSA-70724 https://reactome.org/PathwayBrowser/#/R-HSA-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] TAS Homo sapiens 11851 R-ALL-113584 KIV [mitochondrial matrix] R-HSA-9859148 https://reactome.org/PathwayBrowser/#/R-HSA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV TAS Homo sapiens 11851 R-ALL-113584 KIV [mitochondrial matrix] R-HSA-9865121 https://reactome.org/PathwayBrowser/#/R-HSA-9865121 BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA TAS Homo sapiens 11851 R-ALL-113584 KIV [mitochondrial matrix] R-MMU-508179 https://reactome.org/PathwayBrowser/#/R-MMU-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Mus musculus 11851 R-ALL-70846 KIV [cytosol] R-MMU-508189 https://reactome.org/PathwayBrowser/#/R-MMU-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Mus musculus 11851 R-ALL-70846 KIV [cytosol] R-MMU-70723 https://reactome.org/PathwayBrowser/#/R-MMU-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Mus musculus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-MMU-70724 https://reactome.org/PathwayBrowser/#/R-MMU-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Mus musculus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-MMU-9859148 https://reactome.org/PathwayBrowser/#/R-MMU-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Mus musculus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-PFA-9859148 https://reactome.org/PathwayBrowser/#/R-PFA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Plasmodium falciparum 11851 R-ALL-113584 KIV [mitochondrial matrix] R-RNO-508179 https://reactome.org/PathwayBrowser/#/R-RNO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Rattus norvegicus 11851 R-ALL-70846 KIV [cytosol] R-RNO-508189 https://reactome.org/PathwayBrowser/#/R-RNO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Rattus norvegicus 11851 R-ALL-70846 KIV [cytosol] R-RNO-70723 https://reactome.org/PathwayBrowser/#/R-RNO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Rattus norvegicus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-RNO-70724 https://reactome.org/PathwayBrowser/#/R-RNO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Rattus norvegicus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-RNO-9859148 https://reactome.org/PathwayBrowser/#/R-RNO-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Rattus norvegicus 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SCE-508179 https://reactome.org/PathwayBrowser/#/R-SCE-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Saccharomyces cerevisiae 11851 R-ALL-70846 KIV [cytosol] R-SCE-508189 https://reactome.org/PathwayBrowser/#/R-SCE-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Saccharomyces cerevisiae 11851 R-ALL-70846 KIV [cytosol] R-SCE-70723 https://reactome.org/PathwayBrowser/#/R-SCE-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Saccharomyces cerevisiae 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SCE-70724 https://reactome.org/PathwayBrowser/#/R-SCE-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Saccharomyces cerevisiae 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SPO-508179 https://reactome.org/PathwayBrowser/#/R-SPO-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Schizosaccharomyces pombe 11851 R-ALL-70846 KIV [cytosol] R-SPO-508189 https://reactome.org/PathwayBrowser/#/R-SPO-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Schizosaccharomyces pombe 11851 R-ALL-70846 KIV [cytosol] R-SPO-70723 https://reactome.org/PathwayBrowser/#/R-SPO-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Schizosaccharomyces pombe 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SPO-70724 https://reactome.org/PathwayBrowser/#/R-SPO-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Schizosaccharomyces pombe 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SSC-508179 https://reactome.org/PathwayBrowser/#/R-SSC-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Sus scrofa 11851 R-ALL-70846 KIV [cytosol] R-SSC-508189 https://reactome.org/PathwayBrowser/#/R-SSC-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Sus scrofa 11851 R-ALL-70846 KIV [cytosol] R-SSC-70723 https://reactome.org/PathwayBrowser/#/R-SSC-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Sus scrofa 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SSC-70724 https://reactome.org/PathwayBrowser/#/R-SSC-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Sus scrofa 11851 R-ALL-113584 KIV [mitochondrial matrix] R-SSC-9859148 https://reactome.org/PathwayBrowser/#/R-SSC-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Sus scrofa 11851 R-ALL-113584 KIV [mitochondrial matrix] R-XTR-508179 https://reactome.org/PathwayBrowser/#/R-XTR-508179 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] IEA Xenopus tropicalis 11851 R-ALL-70846 KIV [cytosol] R-XTR-508189 https://reactome.org/PathwayBrowser/#/R-XTR-508189 a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] IEA Xenopus tropicalis 11851 R-ALL-70846 KIV [cytosol] R-XTR-70723 https://reactome.org/PathwayBrowser/#/R-XTR-70723 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] IEA Xenopus tropicalis 11851 R-ALL-113584 KIV [mitochondrial matrix] R-XTR-70724 https://reactome.org/PathwayBrowser/#/R-XTR-70724 leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] IEA Xenopus tropicalis 11851 R-ALL-113584 KIV [mitochondrial matrix] R-XTR-9859148 https://reactome.org/PathwayBrowser/#/R-XTR-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Xenopus tropicalis 11892 R-ALL-73588 UPROP [cytosol] R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 11892 R-ALL-73588 UPROP [cytosol] R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 11892 R-ALL-73588 UPROP [cytosol] R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 11892 R-ALL-73588 UPROP [cytosol] R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 11892 R-ALL-73588 UPROP [cytosol] R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 11892 R-ALL-73588 UPROP [cytosol] R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 11892 R-ALL-73588 UPROP [cytosol] R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 11892 R-ALL-73588 UPROP [cytosol] R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 11892 R-ALL-73588 UPROP [cytosol] R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 11892 R-ALL-73588 UPROP [cytosol] R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 11892 R-ALL-73588 UPROP [cytosol] R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 11892 R-ALL-73588 UPROP [cytosol] R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 11892 R-ALL-73588 UPROP [cytosol] R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 11892 R-ALL-73588 UPROP [cytosol] R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 11892 R-ALL-73588 UPROP [cytosol] R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 11892 R-ALL-73588 UPROP [cytosol] R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 11892 R-ALL-73588 UPROP [cytosol] R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 11892 R-ALL-73588 UPROP [cytosol] R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 11892 R-ALL-73588 UPROP [cytosol] R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 11892 R-ALL-73588 UPROP [cytosol] R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 11892 R-ALL-73588 UPROP [cytosol] R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 11892 R-ALL-73588 UPROP [cytosol] R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 11892 R-ALL-73588 UPROP [cytosol] R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 12387 R-ALL-6787542 Fuc1P [cytosol] R-BTA-6787533 https://reactome.org/PathwayBrowser/#/R-BTA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Bos taurus 12387 R-ALL-6787542 Fuc1P [cytosol] R-BTA-6787540 https://reactome.org/PathwayBrowser/#/R-BTA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Bos taurus 12387 R-ALL-6787542 Fuc1P [cytosol] R-CEL-6787533 https://reactome.org/PathwayBrowser/#/R-CEL-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Caenorhabditis elegans 12387 R-ALL-6787542 Fuc1P [cytosol] R-CEL-6787540 https://reactome.org/PathwayBrowser/#/R-CEL-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Caenorhabditis elegans 12387 R-ALL-6787542 Fuc1P [cytosol] R-CFA-6787533 https://reactome.org/PathwayBrowser/#/R-CFA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Canis familiaris 12387 R-ALL-6787542 Fuc1P [cytosol] R-CFA-6787540 https://reactome.org/PathwayBrowser/#/R-CFA-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Canis familiaris 12387 R-ALL-6787542 Fuc1P [cytosol] R-DDI-6787533 https://reactome.org/PathwayBrowser/#/R-DDI-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Dictyostelium discoideum 12387 R-ALL-6787542 Fuc1P [cytosol] R-DDI-6787540 https://reactome.org/PathwayBrowser/#/R-DDI-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Dictyostelium discoideum 12387 R-ALL-6787542 Fuc1P [cytosol] R-GGA-6787533 https://reactome.org/PathwayBrowser/#/R-GGA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Gallus gallus 12387 R-ALL-6787542 Fuc1P [cytosol] R-HSA-6787533 https://reactome.org/PathwayBrowser/#/R-HSA-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc TAS Homo sapiens 12387 R-ALL-6787542 Fuc1P [cytosol] R-HSA-6787540 https://reactome.org/PathwayBrowser/#/R-HSA-6787540 FUK phosphorylates beta-Fuc to Fuc1P TAS Homo sapiens 12387 R-ALL-6787542 Fuc1P [cytosol] R-MMU-6787533 https://reactome.org/PathwayBrowser/#/R-MMU-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Mus musculus 12387 R-ALL-6787542 Fuc1P [cytosol] R-MMU-6787540 https://reactome.org/PathwayBrowser/#/R-MMU-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Mus musculus 12387 R-ALL-6787542 Fuc1P [cytosol] R-RNO-6787533 https://reactome.org/PathwayBrowser/#/R-RNO-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Rattus norvegicus 12387 R-ALL-6787542 Fuc1P [cytosol] R-RNO-6787540 https://reactome.org/PathwayBrowser/#/R-RNO-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Rattus norvegicus 12387 R-ALL-6787542 Fuc1P [cytosol] R-SSC-6787533 https://reactome.org/PathwayBrowser/#/R-SSC-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Sus scrofa 12387 R-ALL-6787542 Fuc1P [cytosol] R-SSC-6787540 https://reactome.org/PathwayBrowser/#/R-SSC-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Sus scrofa 12387 R-ALL-6787542 Fuc1P [cytosol] R-XTR-6787533 https://reactome.org/PathwayBrowser/#/R-XTR-6787533 FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc IEA Xenopus tropicalis 12387 R-ALL-6787542 Fuc1P [cytosol] R-XTR-6787540 https://reactome.org/PathwayBrowser/#/R-XTR-6787540 FUK phosphorylates beta-Fuc to Fuc1P IEA Xenopus tropicalis 124965 R-ALL-9695928 opaganib [cytosol] R-BTA-9695917 https://reactome.org/PathwayBrowser/#/R-BTA-9695917 SPHK2 binds SPHK2 inhibitors IEA Bos taurus 124965 R-ALL-9695928 opaganib [cytosol] R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 124965 R-ALL-9695928 opaganib [cytosol] R-CEL-9695917 https://reactome.org/PathwayBrowser/#/R-CEL-9695917 SPHK2 binds SPHK2 inhibitors IEA Caenorhabditis elegans 124965 R-ALL-9695928 opaganib [cytosol] R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 124965 R-ALL-9695928 opaganib [cytosol] R-CFA-9695917 https://reactome.org/PathwayBrowser/#/R-CFA-9695917 SPHK2 binds SPHK2 inhibitors IEA Canis familiaris 124965 R-ALL-9695928 opaganib [cytosol] R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 124965 R-ALL-9695928 opaganib [cytosol] R-DDI-9695917 https://reactome.org/PathwayBrowser/#/R-DDI-9695917 SPHK2 binds SPHK2 inhibitors IEA Dictyostelium discoideum 124965 R-ALL-9695928 opaganib [cytosol] R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 124965 R-ALL-9695928 opaganib [cytosol] R-DME-9695917 https://reactome.org/PathwayBrowser/#/R-DME-9695917 SPHK2 binds SPHK2 inhibitors IEA Drosophila melanogaster 124965 R-ALL-9695928 opaganib [cytosol] R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 124965 R-ALL-9695928 opaganib [cytosol] R-HSA-9695917 https://reactome.org/PathwayBrowser/#/R-HSA-9695917 SPHK2 binds SPHK2 inhibitors TAS Homo sapiens 124965 R-ALL-9695928 opaganib [cytosol] R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 124965 R-ALL-9695928 opaganib [cytosol] R-MMU-9695917 https://reactome.org/PathwayBrowser/#/R-MMU-9695917 SPHK2 binds SPHK2 inhibitors IEA Mus musculus 124965 R-ALL-9695928 opaganib [cytosol] R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 124965 R-ALL-9695928 opaganib [cytosol] R-RNO-9695917 https://reactome.org/PathwayBrowser/#/R-RNO-9695917 SPHK2 binds SPHK2 inhibitors IEA Rattus norvegicus 124965 R-ALL-9695928 opaganib [cytosol] R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 124965 R-ALL-9695928 opaganib [cytosol] R-SCE-9695917 https://reactome.org/PathwayBrowser/#/R-SCE-9695917 SPHK2 binds SPHK2 inhibitors IEA Saccharomyces cerevisiae 124965 R-ALL-9695928 opaganib [cytosol] R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 124965 R-ALL-9695928 opaganib [cytosol] R-SPO-9695917 https://reactome.org/PathwayBrowser/#/R-SPO-9695917 SPHK2 binds SPHK2 inhibitors IEA Schizosaccharomyces pombe 124965 R-ALL-9695928 opaganib [cytosol] R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 124965 R-ALL-9695928 opaganib [cytosol] R-SSC-9695917 https://reactome.org/PathwayBrowser/#/R-SSC-9695917 SPHK2 binds SPHK2 inhibitors IEA Sus scrofa 124965 R-ALL-9695928 opaganib [cytosol] R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 124965 R-ALL-9695928 opaganib [cytosol] R-XTR-9695917 https://reactome.org/PathwayBrowser/#/R-XTR-9695917 SPHK2 binds SPHK2 inhibitors IEA Xenopus tropicalis 124965 R-ALL-9695928 opaganib [cytosol] R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 125616 R-ALL-9687670 IM-12 [cytosol] R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 125616 R-ALL-9687670 IM-12 [cytosol] R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 125616 R-ALL-9687670 IM-12 [cytosol] R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-BTA-191382 https://reactome.org/PathwayBrowser/#/R-BTA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Bos taurus 128769 R-ALL-191362 IPPP [cytosol] R-BTA-191414 https://reactome.org/PathwayBrowser/#/R-BTA-191414 MVD decarboxylates MVA5PP to IPPP IEA Bos taurus 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-BTA-2162253 https://reactome.org/PathwayBrowser/#/R-BTA-2162253 PDSS1,2 ligates FPP to IPPP IEA Bos taurus 128769 R-ALL-191362 IPPP [cytosol] R-BTA-4419978 https://reactome.org/PathwayBrowser/#/R-BTA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Bos taurus 128769 R-ALL-191362 IPPP [cytosol] R-BTA-9717830 https://reactome.org/PathwayBrowser/#/R-BTA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Bos taurus 128769 R-ALL-191362 IPPP [cytosol] R-BTA-9717834 https://reactome.org/PathwayBrowser/#/R-BTA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Bos taurus 128769 R-ALL-191362 IPPP [cytosol] R-CEL-191303 https://reactome.org/PathwayBrowser/#/R-CEL-191303 FDPS dimer transfers IPPP to GPP IEA Caenorhabditis elegans 128769 R-ALL-191362 IPPP [cytosol] R-CEL-191322 https://reactome.org/PathwayBrowser/#/R-CEL-191322 FDPS dimer transfers IPPP to DMAPP IEA Caenorhabditis elegans 128769 R-ALL-191362 IPPP [cytosol] R-CEL-191382 https://reactome.org/PathwayBrowser/#/R-CEL-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Caenorhabditis elegans 128769 R-ALL-191362 IPPP [cytosol] R-CEL-191414 https://reactome.org/PathwayBrowser/#/R-CEL-191414 MVD decarboxylates MVA5PP to IPPP IEA Caenorhabditis elegans 128769 R-ALL-191362 IPPP [cytosol] R-CEL-4419978 https://reactome.org/PathwayBrowser/#/R-CEL-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Caenorhabditis elegans 128769 R-ALL-191362 IPPP [cytosol] R-CFA-191303 https://reactome.org/PathwayBrowser/#/R-CFA-191303 FDPS dimer transfers IPPP to GPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-191322 https://reactome.org/PathwayBrowser/#/R-CFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-191382 https://reactome.org/PathwayBrowser/#/R-CFA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-191414 https://reactome.org/PathwayBrowser/#/R-CFA-191414 MVD decarboxylates MVA5PP to IPPP IEA Canis familiaris 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-CFA-2162253 https://reactome.org/PathwayBrowser/#/R-CFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-4419978 https://reactome.org/PathwayBrowser/#/R-CFA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-9717830 https://reactome.org/PathwayBrowser/#/R-CFA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-CFA-9717834 https://reactome.org/PathwayBrowser/#/R-CFA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Canis familiaris 128769 R-ALL-191362 IPPP [cytosol] R-DDI-191303 https://reactome.org/PathwayBrowser/#/R-DDI-191303 FDPS dimer transfers IPPP to GPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-191322 https://reactome.org/PathwayBrowser/#/R-DDI-191322 FDPS dimer transfers IPPP to DMAPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-191382 https://reactome.org/PathwayBrowser/#/R-DDI-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-191414 https://reactome.org/PathwayBrowser/#/R-DDI-191414 MVD decarboxylates MVA5PP to IPPP IEA Dictyostelium discoideum 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-DDI-2162253 https://reactome.org/PathwayBrowser/#/R-DDI-2162253 PDSS1,2 ligates FPP to IPPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-4419978 https://reactome.org/PathwayBrowser/#/R-DDI-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-9717830 https://reactome.org/PathwayBrowser/#/R-DDI-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DDI-9717834 https://reactome.org/PathwayBrowser/#/R-DDI-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Dictyostelium discoideum 128769 R-ALL-191362 IPPP [cytosol] R-DME-191303 https://reactome.org/PathwayBrowser/#/R-DME-191303 FDPS dimer transfers IPPP to GPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-191322 https://reactome.org/PathwayBrowser/#/R-DME-191322 FDPS dimer transfers IPPP to DMAPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-191382 https://reactome.org/PathwayBrowser/#/R-DME-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-191414 https://reactome.org/PathwayBrowser/#/R-DME-191414 MVD decarboxylates MVA5PP to IPPP IEA Drosophila melanogaster 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-DME-2162253 https://reactome.org/PathwayBrowser/#/R-DME-2162253 PDSS1,2 ligates FPP to IPPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-4419978 https://reactome.org/PathwayBrowser/#/R-DME-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-9717830 https://reactome.org/PathwayBrowser/#/R-DME-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DME-9717834 https://reactome.org/PathwayBrowser/#/R-DME-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Drosophila melanogaster 128769 R-ALL-191362 IPPP [cytosol] R-DRE-191303 https://reactome.org/PathwayBrowser/#/R-DRE-191303 FDPS dimer transfers IPPP to GPP IEA Danio rerio 128769 R-ALL-191362 IPPP [cytosol] R-DRE-191322 https://reactome.org/PathwayBrowser/#/R-DRE-191322 FDPS dimer transfers IPPP to DMAPP IEA Danio rerio 128769 R-ALL-191362 IPPP [cytosol] R-DRE-191414 https://reactome.org/PathwayBrowser/#/R-DRE-191414 MVD decarboxylates MVA5PP to IPPP IEA Danio rerio 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-DRE-2162253 https://reactome.org/PathwayBrowser/#/R-DRE-2162253 PDSS1,2 ligates FPP to IPPP IEA Danio rerio 128769 R-ALL-191362 IPPP [cytosol] R-DRE-4419978 https://reactome.org/PathwayBrowser/#/R-DRE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Danio rerio 128769 R-ALL-191362 IPPP [cytosol] R-GGA-191303 https://reactome.org/PathwayBrowser/#/R-GGA-191303 FDPS dimer transfers IPPP to GPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-191322 https://reactome.org/PathwayBrowser/#/R-GGA-191322 FDPS dimer transfers IPPP to DMAPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-191382 https://reactome.org/PathwayBrowser/#/R-GGA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-191414 https://reactome.org/PathwayBrowser/#/R-GGA-191414 MVD decarboxylates MVA5PP to IPPP IEA Gallus gallus 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-GGA-2162253 https://reactome.org/PathwayBrowser/#/R-GGA-2162253 PDSS1,2 ligates FPP to IPPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-9717830 https://reactome.org/PathwayBrowser/#/R-GGA-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-GGA-9717834 https://reactome.org/PathwayBrowser/#/R-GGA-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Gallus gallus 128769 R-ALL-191362 IPPP [cytosol] R-HSA-191303 https://reactome.org/PathwayBrowser/#/R-HSA-191303 FDPS dimer transfers IPPP to GPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-191322 https://reactome.org/PathwayBrowser/#/R-HSA-191322 FDPS dimer transfers IPPP to DMAPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-191382 https://reactome.org/PathwayBrowser/#/R-HSA-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-191414 https://reactome.org/PathwayBrowser/#/R-HSA-191414 MVD decarboxylates MVA5PP to IPPP TAS Homo sapiens 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-HSA-2162253 https://reactome.org/PathwayBrowser/#/R-HSA-2162253 PDSS1,2 ligates FPP to IPPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-4419978 https://reactome.org/PathwayBrowser/#/R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-4755545 https://reactome.org/PathwayBrowser/#/R-HSA-4755545 Defective DHDDS does not elongate E,E-FPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-9717830 https://reactome.org/PathwayBrowser/#/R-HSA-9717830 GGPS1 hexamer transfers IPPP to GPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-HSA-9717834 https://reactome.org/PathwayBrowser/#/R-HSA-9717834 GGPS1 hexamer transfers IPPP to DMAPP TAS Homo sapiens 128769 R-ALL-191362 IPPP [cytosol] R-MMU-191303 https://reactome.org/PathwayBrowser/#/R-MMU-191303 FDPS dimer transfers IPPP to GPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-191322 https://reactome.org/PathwayBrowser/#/R-MMU-191322 FDPS dimer transfers IPPP to DMAPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-191382 https://reactome.org/PathwayBrowser/#/R-MMU-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-191414 https://reactome.org/PathwayBrowser/#/R-MMU-191414 MVD decarboxylates MVA5PP to IPPP IEA Mus musculus 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-MMU-2162253 https://reactome.org/PathwayBrowser/#/R-MMU-2162253 PDSS1,2 ligates FPP to IPPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-4419978 https://reactome.org/PathwayBrowser/#/R-MMU-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-9717830 https://reactome.org/PathwayBrowser/#/R-MMU-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-MMU-9717834 https://reactome.org/PathwayBrowser/#/R-MMU-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Mus musculus 128769 R-ALL-191362 IPPP [cytosol] R-PFA-191303 https://reactome.org/PathwayBrowser/#/R-PFA-191303 FDPS dimer transfers IPPP to GPP IEA Plasmodium falciparum 128769 R-ALL-191362 IPPP [cytosol] R-PFA-191322 https://reactome.org/PathwayBrowser/#/R-PFA-191322 FDPS dimer transfers IPPP to DMAPP IEA Plasmodium falciparum 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-PFA-2162253 https://reactome.org/PathwayBrowser/#/R-PFA-2162253 PDSS1,2 ligates FPP to IPPP IEA Plasmodium falciparum 128769 R-ALL-191362 IPPP [cytosol] R-RNO-191303 https://reactome.org/PathwayBrowser/#/R-RNO-191303 FDPS dimer transfers IPPP to GPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-191322 https://reactome.org/PathwayBrowser/#/R-RNO-191322 FDPS dimer transfers IPPP to DMAPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-191382 https://reactome.org/PathwayBrowser/#/R-RNO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-191414 https://reactome.org/PathwayBrowser/#/R-RNO-191414 MVD decarboxylates MVA5PP to IPPP IEA Rattus norvegicus 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-RNO-2162253 https://reactome.org/PathwayBrowser/#/R-RNO-2162253 PDSS1,2 ligates FPP to IPPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-4419978 https://reactome.org/PathwayBrowser/#/R-RNO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-9717830 https://reactome.org/PathwayBrowser/#/R-RNO-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-RNO-9717834 https://reactome.org/PathwayBrowser/#/R-RNO-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Rattus norvegicus 128769 R-ALL-191362 IPPP [cytosol] R-SCE-191303 https://reactome.org/PathwayBrowser/#/R-SCE-191303 FDPS dimer transfers IPPP to GPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-191322 https://reactome.org/PathwayBrowser/#/R-SCE-191322 FDPS dimer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-191382 https://reactome.org/PathwayBrowser/#/R-SCE-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-191414 https://reactome.org/PathwayBrowser/#/R-SCE-191414 MVD decarboxylates MVA5PP to IPPP IEA Saccharomyces cerevisiae 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-SCE-2162253 https://reactome.org/PathwayBrowser/#/R-SCE-2162253 PDSS1,2 ligates FPP to IPPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-4419978 https://reactome.org/PathwayBrowser/#/R-SCE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-9717830 https://reactome.org/PathwayBrowser/#/R-SCE-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SCE-9717834 https://reactome.org/PathwayBrowser/#/R-SCE-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Saccharomyces cerevisiae 128769 R-ALL-191362 IPPP [cytosol] R-SPO-191303 https://reactome.org/PathwayBrowser/#/R-SPO-191303 FDPS dimer transfers IPPP to GPP IEA Schizosaccharomyces pombe 128769 R-ALL-191362 IPPP [cytosol] R-SPO-191322 https://reactome.org/PathwayBrowser/#/R-SPO-191322 FDPS dimer transfers IPPP to DMAPP IEA Schizosaccharomyces pombe 128769 R-ALL-191362 IPPP [cytosol] R-SPO-191382 https://reactome.org/PathwayBrowser/#/R-SPO-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Schizosaccharomyces pombe 128769 R-ALL-191362 IPPP [cytosol] R-SPO-191414 https://reactome.org/PathwayBrowser/#/R-SPO-191414 MVD decarboxylates MVA5PP to IPPP IEA Schizosaccharomyces pombe 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-SPO-2162253 https://reactome.org/PathwayBrowser/#/R-SPO-2162253 PDSS1,2 ligates FPP to IPPP IEA Schizosaccharomyces pombe 128769 R-ALL-191362 IPPP [cytosol] R-SPO-4419978 https://reactome.org/PathwayBrowser/#/R-SPO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Schizosaccharomyces pombe 128769 R-ALL-191362 IPPP [cytosol] R-SSC-191303 https://reactome.org/PathwayBrowser/#/R-SSC-191303 FDPS dimer transfers IPPP to GPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-191322 https://reactome.org/PathwayBrowser/#/R-SSC-191322 FDPS dimer transfers IPPP to DMAPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-191382 https://reactome.org/PathwayBrowser/#/R-SSC-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-191414 https://reactome.org/PathwayBrowser/#/R-SSC-191414 MVD decarboxylates MVA5PP to IPPP IEA Sus scrofa 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-SSC-2162253 https://reactome.org/PathwayBrowser/#/R-SSC-2162253 PDSS1,2 ligates FPP to IPPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-4419978 https://reactome.org/PathwayBrowser/#/R-SSC-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-9717830 https://reactome.org/PathwayBrowser/#/R-SSC-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-SSC-9717834 https://reactome.org/PathwayBrowser/#/R-SSC-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Sus scrofa 128769 R-ALL-191362 IPPP [cytosol] R-XTR-191382 https://reactome.org/PathwayBrowser/#/R-XTR-191382 Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate IEA Xenopus tropicalis 128769 R-ALL-191362 IPPP [cytosol] R-XTR-191414 https://reactome.org/PathwayBrowser/#/R-XTR-191414 MVD decarboxylates MVA5PP to IPPP IEA Xenopus tropicalis 128769 R-ALL-2162256 IPPP [mitochondrial matrix] R-XTR-2162253 https://reactome.org/PathwayBrowser/#/R-XTR-2162253 PDSS1,2 ligates FPP to IPPP IEA Xenopus tropicalis 128769 R-ALL-191362 IPPP [cytosol] R-XTR-9717830 https://reactome.org/PathwayBrowser/#/R-XTR-9717830 GGPS1 hexamer transfers IPPP to GPP IEA Xenopus tropicalis 128769 R-ALL-191362 IPPP [cytosol] R-XTR-9717834 https://reactome.org/PathwayBrowser/#/R-XTR-9717834 GGPS1 hexamer transfers IPPP to DMAPP IEA Xenopus tropicalis 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 1294 R-ALL-193086 20a,22b-DHCHOL [mitochondrial inner membrane] R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-BTA-4720432 https://reactome.org/PathwayBrowser/#/R-BTA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Bos taurus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-BTA-4720446 https://reactome.org/PathwayBrowser/#/R-BTA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Bos taurus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-DME-4720432 https://reactome.org/PathwayBrowser/#/R-DME-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Drosophila melanogaster 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-DME-4720446 https://reactome.org/PathwayBrowser/#/R-DME-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Drosophila melanogaster 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-GGA-4720446 https://reactome.org/PathwayBrowser/#/R-GGA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Gallus gallus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-HSA-4720432 https://reactome.org/PathwayBrowser/#/R-HSA-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 TAS Homo sapiens 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-HSA-4720446 https://reactome.org/PathwayBrowser/#/R-HSA-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 TAS Homo sapiens 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-MMU-4720432 https://reactome.org/PathwayBrowser/#/R-MMU-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Mus musculus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-MMU-4720446 https://reactome.org/PathwayBrowser/#/R-MMU-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Mus musculus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-RNO-4720432 https://reactome.org/PathwayBrowser/#/R-RNO-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Rattus norvegicus 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-RNO-4720446 https://reactome.org/PathwayBrowser/#/R-RNO-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Rattus norvegicus 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-SSC-4720432 https://reactome.org/PathwayBrowser/#/R-SSC-4720432 HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 IEA Sus scrofa 1301 R-ALL-4720434 22beta-hydroxycholesterol [nucleoplasm] R-SSC-4720446 https://reactome.org/PathwayBrowser/#/R-SSC-4720446 HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 IEA Sus scrofa 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 1301 R-ALL-193019 22b-HCHOL [mitochondrial inner membrane] R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 13115 R-ALL-5661268 L-gulonate [cytosol] R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 13115 R-ALL-5661268 L-gulonate [cytosol] R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 13115 R-ALL-5661268 L-gulonate [cytosol] R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 13115 R-ALL-5661268 L-gulonate [cytosol] R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 13115 R-ALL-5661268 L-gulonate [cytosol] R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 13115 R-ALL-5661268 L-gulonate [cytosol] R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 13115 R-ALL-5661268 L-gulonate [cytosol] R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 13115 R-ALL-5661268 L-gulonate [cytosol] R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 13115 R-ALL-5661268 L-gulonate [cytosol] R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 13115 R-ALL-5661268 L-gulonate [cytosol] R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 13115 R-ALL-5661268 L-gulonate [cytosol] R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 13115 R-ALL-5661268 L-gulonate [cytosol] R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 13115 R-ALL-5661268 L-gulonate [cytosol] R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 13115 R-ALL-5661268 L-gulonate [cytosol] R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 13115 R-ALL-5661268 L-gulonate [cytosol] R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 13115 R-ALL-5661268 L-gulonate [cytosol] R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 13115 R-ALL-5661268 L-gulonate [cytosol] R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 13115 R-ALL-5661268 L-gulonate [cytosol] R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 13115 R-ALL-5661268 L-gulonate [cytosol] R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 13115 R-ALL-5661268 L-gulonate [cytosol] R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 13115 R-ALL-5661268 L-gulonate [cytosol] R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 13115 R-ALL-5661268 L-gulonate [cytosol] R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 13115 R-ALL-5661268 L-gulonate [cytosol] R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 13115 R-ALL-5661268 L-gulonate [cytosol] R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 13115 R-ALL-5661268 L-gulonate [cytosol] R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 131490 R-ALL-9687680 azakenpaullone [cytosol] R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 131490 R-ALL-9687680 azakenpaullone [cytosol] R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 131490 R-ALL-9687680 azakenpaullone [cytosol] R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 131512 R-ALL-9677972 tranylcypromine [cytosol] R-BTA-9677917 https://reactome.org/PathwayBrowser/#/R-BTA-9677917 MAOA inhibitors bind MAOA:FAD IEA Bos taurus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-CFA-9677917 https://reactome.org/PathwayBrowser/#/R-CFA-9677917 MAOA inhibitors bind MAOA:FAD IEA Canis familiaris 131512 R-ALL-9677972 tranylcypromine [cytosol] R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 131512 R-ALL-9677972 tranylcypromine [cytosol] R-DDI-9677917 https://reactome.org/PathwayBrowser/#/R-DDI-9677917 MAOA inhibitors bind MAOA:FAD IEA Dictyostelium discoideum 131512 R-ALL-9677972 tranylcypromine [cytosol] R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 131512 R-ALL-9677972 tranylcypromine [cytosol] R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 131512 R-ALL-9677972 tranylcypromine [cytosol] R-GGA-9677917 https://reactome.org/PathwayBrowser/#/R-GGA-9677917 MAOA inhibitors bind MAOA:FAD IEA Gallus gallus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-HSA-9677917 https://reactome.org/PathwayBrowser/#/R-HSA-9677917 MAOA inhibitors bind MAOA:FAD TAS Homo sapiens 131512 R-ALL-9677972 tranylcypromine [cytosol] R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 131512 R-ALL-9677972 tranylcypromine [cytosol] R-MMU-9677917 https://reactome.org/PathwayBrowser/#/R-MMU-9677917 MAOA inhibitors bind MAOA:FAD IEA Mus musculus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-RNO-9677917 https://reactome.org/PathwayBrowser/#/R-RNO-9677917 MAOA inhibitors bind MAOA:FAD IEA Rattus norvegicus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 131512 R-ALL-9677972 tranylcypromine [cytosol] R-SSC-9677917 https://reactome.org/PathwayBrowser/#/R-SSC-9677917 MAOA inhibitors bind MAOA:FAD IEA Sus scrofa 131512 R-ALL-9677972 tranylcypromine [cytosol] R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 131512 R-ALL-9677972 tranylcypromine [cytosol] R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 13166 R-HSA-5357708 Sec-tRNA(Sec) [cytosol] R-HSA-2408509 https://reactome.org/PathwayBrowser/#/R-HSA-2408509 Sec-tRNA(Sec) binds to EEFSEC:GTP IEA Homo sapiens 13166 R-HSA-5357708 Sec-tRNA(Sec) [cytosol] R-HSA-2408529 https://reactome.org/PathwayBrowser/#/R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome IEA Homo sapiens 13166 R-HSA-5357708 Sec-tRNA(Sec) [cytosol] R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 13166 R-HSA-5357708 Sec-tRNA(Sec) [cytosol] R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 13166 R-MMU-5603444 Sec-tRNA(Sec) [cytosol] R-MMU-2408515 https://reactome.org/PathwayBrowser/#/R-MMU-2408515 Sec-tRNA(Sec) binds to Eefsec:GTP TAS Mus musculus 13166 R-RNO-5603446 Sec-tRNA(Sec) [cytosol] R-RNO-2408535 https://reactome.org/PathwayBrowser/#/R-RNO-2408535 Sec-tRNA(Sec):Eefsec:GTP binds to Rpl30 TAS Rattus norvegicus 13166 R-RNO-5603446 Sec-tRNA(Sec) [cytosol] R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 13170 R-HSA-5357730 Ser-tRNA(Sec) [cytosol] R-HSA-2408507 https://reactome.org/PathwayBrowser/#/R-HSA-2408507 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK IEA Homo sapiens 13170 R-HSA-5357730 Ser-tRNA(Sec) [cytosol] R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 13170 R-MMU-5603447 Ser-tRNA(Sec) [cytosol] R-MMU-2408505 https://reactome.org/PathwayBrowser/#/R-MMU-2408505 Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk TAS Mus musculus 131727 R-ALL-1222348 Lipid-OH [cytosol] R-HSA-1222526 https://reactome.org/PathwayBrowser/#/R-HSA-1222526 AhpC reduces peroxidated lipids TAS Homo sapiens 131825 R-ALL-6789106 8,5'-cdA [cytoplasm] R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 131825 R-ALL-6789053 8,5'-cdG [cytoplasm] R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 131880 R-ALL-9657547 SB590885 [cytosol] R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 131882 R-ALL-9657547 SB590885 [cytosol] R-HSA-6802938 https://reactome.org/PathwayBrowser/#/R-HSA-6802938 Inhibitors bind and inhibit highly active BRAF mutants TAS Homo sapiens 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 TAS Homo sapiens 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-RNO-9027532 https://reactome.org/PathwayBrowser/#/R-RNO-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Rattus norvegicus 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-SSC-9027532 https://reactome.org/PathwayBrowser/#/R-SSC-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Sus scrofa 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 13193 R-ALL-9915551 hydrogen acceptor [endoplasmic reticulum lumen] R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 13193 R-ALL-9757044 hydrogen acceptor [mitochondrial matrix] R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 13193 R-ALL-1130886 hydrogen acceptor [cytosol] R-XTR-9027532 https://reactome.org/PathwayBrowser/#/R-XTR-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Xenopus tropicalis 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-BTA-9026777 https://reactome.org/PathwayBrowser/#/R-BTA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-BTA-9026780 https://reactome.org/PathwayBrowser/#/R-BTA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-CFA-9026777 https://reactome.org/PathwayBrowser/#/R-CFA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-CFA-9026780 https://reactome.org/PathwayBrowser/#/R-CFA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DDI-9026780 https://reactome.org/PathwayBrowser/#/R-DDI-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Dictyostelium discoideum 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-DRE-9026777 https://reactome.org/PathwayBrowser/#/R-DRE-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Danio rerio 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-GGA-9026780 https://reactome.org/PathwayBrowser/#/R-GGA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9026777 https://reactome.org/PathwayBrowser/#/R-HSA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-HSA-9026780 https://reactome.org/PathwayBrowser/#/R-HSA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-MMU-9026777 https://reactome.org/PathwayBrowser/#/R-MMU-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-MMU-9026780 https://reactome.org/PathwayBrowser/#/R-MMU-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-RNO-9026777 https://reactome.org/PathwayBrowser/#/R-RNO-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-RNO-9026780 https://reactome.org/PathwayBrowser/#/R-RNO-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-SSC-9026777 https://reactome.org/PathwayBrowser/#/R-SSC-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-SSC-9026780 https://reactome.org/PathwayBrowser/#/R-SSC-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-XTR-9026777 https://reactome.org/PathwayBrowser/#/R-XTR-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 131958 R-ALL-9025001 13(S),14(S)-epoxy-DHA [cytosol] R-XTR-9026780 https://reactome.org/PathwayBrowser/#/R-XTR-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 131992 R-ALL-2142739 5,6-EET [cytosol] R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 131992 R-ALL-2142739 5,6-EET [cytosol] R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Bos taurus 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 131992 R-ALL-2142739 5,6-EET [cytosol] R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 131992 R-ALL-2142739 5,6-EET [cytosol] R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 131992 R-ALL-2142739 5,6-EET [cytosol] R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Canis familiaris 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 131992 R-ALL-2142739 5,6-EET [cytosol] R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 131992 R-ALL-2142739 5,6-EET [cytosol] R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Dictyostelium discoideum 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 131992 R-ALL-2142739 5,6-EET [cytosol] R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 131992 R-ALL-2142739 5,6-EET [cytosol] R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 131992 R-ALL-2142739 5,6-EET [cytosol] R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Danio rerio 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 131992 R-ALL-2142739 5,6-EET [cytosol] R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 131992 R-ALL-2142739 5,6-EET [cytosol] R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Gallus gallus 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 131992 R-ALL-2142739 5,6-EET [cytosol] R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 131992 R-ALL-2142739 5,6-EET [cytosol] R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 TAS Homo sapiens 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 131992 R-ALL-2142739 5,6-EET [cytosol] R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 131992 R-ALL-2142739 5,6-EET [cytosol] R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Mus musculus 131992 R-ALL-2142739 5,6-EET [cytosol] R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Plasmodium falciparum 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 131992 R-ALL-2142739 5,6-EET [cytosol] R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 131992 R-ALL-2142739 5,6-EET [cytosol] R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Rattus norvegicus 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 131992 R-ALL-2142739 5,6-EET [cytosol] R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 131992 R-ALL-2142739 5,6-EET [cytosol] R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Sus scrofa 131992 R-ALL-215087 5,6-EET [endoplasmic reticulum lumen] R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 131992 R-ALL-2142739 5,6-EET [cytosol] R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 131992 R-ALL-2142739 5,6-EET [cytosol] R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Xenopus tropicalis 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-RNO-9915992 https://reactome.org/PathwayBrowser/#/R-RNO-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Rattus norvegicus 132016 R-ALL-2142711 17-HETE [endoplasmic reticulum lumen] R-SSC-9915992 https://reactome.org/PathwayBrowser/#/R-SSC-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Sus scrofa 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 132019 R-ALL-2142667 16-HETE [endoplasmic reticulum lumen] R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Sus scrofa 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 132023 R-ALL-6810530 acyl-PPANT [peroxisomal matrix] R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 132041 R-ALL-9614952 perindoprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 132041 R-ALL-9614952 perindoprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 132041 R-ALL-9614952 perindoprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 132041 R-ALL-9614952 perindoprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 132041 R-ALL-9614952 perindoprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 132041 R-ALL-9614952 perindoprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 132041 R-ALL-9614952 perindoprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 132041 R-ALL-9614952 perindoprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 132041 R-ALL-9614952 perindoprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 132041 R-ALL-9614952 perindoprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 132041 R-ALL-9614952 perindoprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 132041 R-ALL-9614952 perindoprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 132041 R-ALL-9614952 perindoprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 132041 R-ALL-9614952 perindoprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 132041 R-ALL-9619044 perindoprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 132070 R-ALL-2142772 EXA4 [cytosol] R-BTA-2161768 https://reactome.org/PathwayBrowser/#/R-BTA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Bos taurus 132070 R-ALL-2142772 EXA4 [cytosol] R-BTA-2162019 https://reactome.org/PathwayBrowser/#/R-BTA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Bos taurus 132070 R-ALL-2142772 EXA4 [cytosol] R-CFA-2161768 https://reactome.org/PathwayBrowser/#/R-CFA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Canis familiaris 132070 R-ALL-2142772 EXA4 [cytosol] R-CFA-2162019 https://reactome.org/PathwayBrowser/#/R-CFA-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Canis familiaris 132070 R-ALL-2142772 EXA4 [cytosol] R-DDI-2161768 https://reactome.org/PathwayBrowser/#/R-DDI-2161768 EXA4 is converted to EXC4 by LTC4S IEA Dictyostelium discoideum 132070 R-ALL-2142772 EXA4 [cytosol] R-DDI-2162019 https://reactome.org/PathwayBrowser/#/R-DDI-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Dictyostelium discoideum 132070 R-ALL-2142772 EXA4 [cytosol] R-DRE-2162019 https://reactome.org/PathwayBrowser/#/R-DRE-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Danio rerio 132070 R-ALL-2142772 EXA4 [cytosol] R-GGA-2161768 https://reactome.org/PathwayBrowser/#/R-GGA-2161768 EXA4 is converted to EXC4 by LTC4S IEA Gallus gallus 132070 R-ALL-2142772 EXA4 [cytosol] R-HSA-2161768 https://reactome.org/PathwayBrowser/#/R-HSA-2161768 EXA4 is converted to EXC4 by LTC4S TAS Homo sapiens 132070 R-ALL-2142772 EXA4 [cytosol] R-HSA-2162019 https://reactome.org/PathwayBrowser/#/R-HSA-2162019 LTA4 is converted to EXA4 by ALOX15 TAS Homo sapiens 132070 R-ALL-2142772 EXA4 [cytosol] R-MMU-2161768 https://reactome.org/PathwayBrowser/#/R-MMU-2161768 EXA4 is converted to EXC4 by LTC4S IEA Mus musculus 132070 R-ALL-2142772 EXA4 [cytosol] R-MMU-2162019 https://reactome.org/PathwayBrowser/#/R-MMU-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Mus musculus 132070 R-ALL-2142772 EXA4 [cytosol] R-RNO-2161768 https://reactome.org/PathwayBrowser/#/R-RNO-2161768 EXA4 is converted to EXC4 by LTC4S IEA Rattus norvegicus 132070 R-ALL-2142772 EXA4 [cytosol] R-RNO-2162019 https://reactome.org/PathwayBrowser/#/R-RNO-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Rattus norvegicus 132070 R-ALL-2142772 EXA4 [cytosol] R-SSC-2161768 https://reactome.org/PathwayBrowser/#/R-SSC-2161768 EXA4 is converted to EXC4 by LTC4S IEA Sus scrofa 132070 R-ALL-2142772 EXA4 [cytosol] R-SSC-2162019 https://reactome.org/PathwayBrowser/#/R-SSC-2162019 LTA4 is converted to EXA4 by ALOX15 IEA Sus scrofa 132070 R-ALL-2142772 EXA4 [cytosol] R-XTR-2161768 https://reactome.org/PathwayBrowser/#/R-XTR-2161768 EXA4 is converted to EXC4 by LTC4S IEA Xenopus tropicalis 132079 R-ALL-9024764 RvD1 [cytosol] R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 132079 R-ALL-9024764 RvD1 [cytosol] R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 132079 R-ALL-9024764 RvD1 [cytosol] R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 132079 R-ALL-9024764 RvD1 [cytosol] R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 132079 R-ALL-9024764 RvD1 [cytosol] R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 132079 R-ALL-9024764 RvD1 [cytosol] R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 132079 R-ALL-9024764 RvD1 [cytosol] R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 132079 R-ALL-9024764 RvD1 [cytosol] R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 132079 R-ALL-9024764 RvD1 [cytosol] R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 132079 R-ALL-9024764 RvD1 [cytosol] R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 132079 R-ALL-9024764 RvD1 [cytosol] R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 132079 R-ALL-9024764 RvD1 [cytosol] R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 132079 R-ALL-9024764 RvD1 [cytosol] R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 132079 R-ALL-9024764 RvD1 [cytosol] R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 132079 R-ALL-9024764 RvD1 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 132079 R-ALL-9024790 RvD1 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 132079 R-ALL-9024764 RvD1 [cytosol] R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 132079 R-ALL-9024764 RvD1 [cytosol] R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 132079 R-ALL-9024764 RvD1 [cytosol] R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 132079 R-ALL-9024764 RvD1 [cytosol] R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 132079 R-ALL-9024764 RvD1 [cytosol] R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 132079 R-ALL-9024764 RvD1 [cytosol] R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 132079 R-ALL-9024764 RvD1 [cytosol] R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 132079 R-ALL-9024764 RvD1 [cytosol] R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 132079 R-ALL-9024764 RvD1 [cytosol] R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 132079 R-ALL-9024764 RvD1 [cytosol] R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 132080 R-ALL-9024804 8-oxo-17(S)-RvD1 [cytosol] R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 132081 R-ALL-9024758 17(S)-oxo-RvD1 [cytosol] R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-RNO-9018858 https://reactome.org/PathwayBrowser/#/R-RNO-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Rattus norvegicus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-RNO-9020610 https://reactome.org/PathwayBrowser/#/R-RNO-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Rattus norvegicus 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-SSC-9018858 https://reactome.org/PathwayBrowser/#/R-SSC-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Sus scrofa 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-SSC-9020610 https://reactome.org/PathwayBrowser/#/R-SSC-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Sus scrofa 132083 R-ALL-9020474 18(S)-HEPE [cytosol] R-XTR-9018858 https://reactome.org/PathwayBrowser/#/R-XTR-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Xenopus tropicalis 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-RNO-9018858 https://reactome.org/PathwayBrowser/#/R-RNO-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Rattus norvegicus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-RNO-9018859 https://reactome.org/PathwayBrowser/#/R-RNO-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Rattus norvegicus 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-SSC-9018858 https://reactome.org/PathwayBrowser/#/R-SSC-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Sus scrofa 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-SSC-9018859 https://reactome.org/PathwayBrowser/#/R-SSC-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Sus scrofa 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-XTR-9018858 https://reactome.org/PathwayBrowser/#/R-XTR-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Xenopus tropicalis 132091 R-ALL-9020602 5(S)-Hp-18(S)-HEPE [cytosol] R-XTR-9018859 https://reactome.org/PathwayBrowser/#/R-XTR-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Xenopus tropicalis 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-BTA-6784224 https://reactome.org/PathwayBrowser/#/R-BTA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Bos taurus 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-CEL-6784224 https://reactome.org/PathwayBrowser/#/R-CEL-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Caenorhabditis elegans 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-CFA-6784224 https://reactome.org/PathwayBrowser/#/R-CFA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Canis familiaris 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-DDI-6784224 https://reactome.org/PathwayBrowser/#/R-DDI-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Dictyostelium discoideum 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-DME-6784224 https://reactome.org/PathwayBrowser/#/R-DME-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Drosophila melanogaster 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-HSA-6784224 https://reactome.org/PathwayBrowser/#/R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate TAS Homo sapiens 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-MMU-6784224 https://reactome.org/PathwayBrowser/#/R-MMU-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Mus musculus 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-RNO-6784224 https://reactome.org/PathwayBrowser/#/R-RNO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Rattus norvegicus 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-SCE-6784224 https://reactome.org/PathwayBrowser/#/R-SCE-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Saccharomyces cerevisiae 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-SPO-6784224 https://reactome.org/PathwayBrowser/#/R-SPO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Schizosaccharomyces pombe 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-SSC-6784224 https://reactome.org/PathwayBrowser/#/R-SSC-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Sus scrofa 132124 R-ALL-9930628 quinone [mitochondrial matrix] R-XTR-6784224 https://reactome.org/PathwayBrowser/#/R-XTR-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Xenopus tropicalis 132127 R-ALL-2142756 HXA3 [cytosol] R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Bos taurus 132127 R-ALL-8942209 HXA3 [cytosol] R-BTA-8942208 https://reactome.org/PathwayBrowser/#/R-BTA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Bos taurus 132127 R-ALL-2142756 HXA3 [cytosol] R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 132127 R-ALL-8942209 HXA3 [cytosol] R-CFA-8942208 https://reactome.org/PathwayBrowser/#/R-CFA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Canis familiaris 132127 R-ALL-2142756 HXA3 [cytosol] R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 132127 R-ALL-8942209 HXA3 [cytosol] R-DDI-8942208 https://reactome.org/PathwayBrowser/#/R-DDI-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Dictyostelium discoideum 132127 R-ALL-2142756 HXA3 [cytosol] R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Danio rerio 132127 R-ALL-8942209 HXA3 [cytosol] R-DRE-8942208 https://reactome.org/PathwayBrowser/#/R-DRE-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Danio rerio 132127 R-ALL-8942209 HXA3 [cytosol] R-GGA-8942208 https://reactome.org/PathwayBrowser/#/R-GGA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Gallus gallus 132127 R-ALL-2142756 HXA3 [cytosol] R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 132127 R-ALL-2142756 HXA3 [cytosol] R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 132127 R-ALL-8942209 HXA3 [cytosol] R-HSA-8942208 https://reactome.org/PathwayBrowser/#/R-HSA-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 TAS Homo sapiens 132127 R-ALL-2142756 HXA3 [cytosol] R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Mus musculus 132127 R-ALL-8942209 HXA3 [cytosol] R-MMU-8942208 https://reactome.org/PathwayBrowser/#/R-MMU-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Mus musculus 132127 R-ALL-2142756 HXA3 [cytosol] R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 132127 R-ALL-8942209 HXA3 [cytosol] R-RNO-8942208 https://reactome.org/PathwayBrowser/#/R-RNO-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Rattus norvegicus 132127 R-ALL-2142756 HXA3 [cytosol] R-SSC-2161794 https://reactome.org/PathwayBrowser/#/R-SSC-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Sus scrofa 132127 R-ALL-8942209 HXA3 [cytosol] R-SSC-8942208 https://reactome.org/PathwayBrowser/#/R-SSC-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Sus scrofa 132127 R-ALL-8942209 HXA3 [cytosol] R-XTR-8942208 https://reactome.org/PathwayBrowser/#/R-XTR-8942208 ALOXE3 isomerises 12R-HpETE to HXA3 IEA Xenopus tropicalis 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-BTA-9018863 https://reactome.org/PathwayBrowser/#/R-BTA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Bos taurus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-CFA-9018863 https://reactome.org/PathwayBrowser/#/R-CFA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Canis familiaris 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-DDI-9018863 https://reactome.org/PathwayBrowser/#/R-DDI-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Dictyostelium discoideum 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-DRE-9018863 https://reactome.org/PathwayBrowser/#/R-DRE-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Danio rerio 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-GGA-9018863 https://reactome.org/PathwayBrowser/#/R-GGA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Gallus gallus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-HSA-9018863 https://reactome.org/PathwayBrowser/#/R-HSA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE TAS Homo sapiens 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 TAS Homo sapiens 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-MMU-9018863 https://reactome.org/PathwayBrowser/#/R-MMU-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Mus musculus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-RNO-9018863 https://reactome.org/PathwayBrowser/#/R-RNO-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Rattus norvegicus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-RNO-9018894 https://reactome.org/PathwayBrowser/#/R-RNO-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Rattus norvegicus 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-SSC-9018863 https://reactome.org/PathwayBrowser/#/R-SSC-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Sus scrofa 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-SSC-9018894 https://reactome.org/PathwayBrowser/#/R-SSC-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Sus scrofa 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-XTR-9018863 https://reactome.org/PathwayBrowser/#/R-XTR-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Xenopus tropicalis 132218 R-ALL-9023702 5(S)-Hp-18(R)-HEPE [cytosol] R-XTR-9018894 https://reactome.org/PathwayBrowser/#/R-XTR-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Xenopus tropicalis 132873 R-ALL-8932801 5-HETEL [extracellular region] R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 132873 R-ALL-8932801 5-HETEL [extracellular region] R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 132873 R-ALL-8932801 5-HETEL [extracellular region] R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 132873 R-ALL-8932801 5-HETEL [extracellular region] R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 132873 R-ALL-8932801 5-HETEL [extracellular region] R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 132873 R-ALL-8932801 5-HETEL [extracellular region] R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 132873 R-ALL-8932801 5-HETEL [extracellular region] R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 132873 R-ALL-8932801 5-HETEL [extracellular region] R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 132873 R-ALL-8932801 5-HETEL [extracellular region] R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 132873 R-ALL-8932801 5-HETEL [extracellular region] R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-BTA-158546 https://reactome.org/PathwayBrowser/#/R-BTA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Bos taurus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CEL-158546 https://reactome.org/PathwayBrowser/#/R-CEL-158546 UGTs glucuronate APAP to APAP-GlcA IEA Caenorhabditis elegans 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CFA-158546 https://reactome.org/PathwayBrowser/#/R-CFA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Canis familiaris 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DDI-158546 https://reactome.org/PathwayBrowser/#/R-DDI-158546 UGTs glucuronate APAP to APAP-GlcA IEA Dictyostelium discoideum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DDI-174931 https://reactome.org/PathwayBrowser/#/R-DDI-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Dictyostelium discoideum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DME-158546 https://reactome.org/PathwayBrowser/#/R-DME-158546 UGTs glucuronate APAP to APAP-GlcA IEA Drosophila melanogaster 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DRE-158546 https://reactome.org/PathwayBrowser/#/R-DRE-158546 UGTs glucuronate APAP to APAP-GlcA IEA Danio rerio 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-GGA-158546 https://reactome.org/PathwayBrowser/#/R-GGA-158546 UGTs glucuronate APAP to APAP-GlcA IEA Gallus gallus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-GGA-174931 https://reactome.org/PathwayBrowser/#/R-GGA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Gallus gallus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-HSA-158546 https://reactome.org/PathwayBrowser/#/R-HSA-158546 UGTs glucuronate APAP to APAP-GlcA TAS Homo sapiens 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-HSA-174931 https://reactome.org/PathwayBrowser/#/R-HSA-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates TAS Homo sapiens 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-MMU-158546 https://reactome.org/PathwayBrowser/#/R-MMU-158546 UGTs glucuronate APAP to APAP-GlcA IEA Mus musculus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-MMU-174931 https://reactome.org/PathwayBrowser/#/R-MMU-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Mus musculus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-RNO-158546 https://reactome.org/PathwayBrowser/#/R-RNO-158546 UGTs glucuronate APAP to APAP-GlcA IEA Rattus norvegicus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-RNO-174931 https://reactome.org/PathwayBrowser/#/R-RNO-174931 UGTs transfer GlcA from UDP-GlcA to O-centre substrates IEA Rattus norvegicus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SSC-158546 https://reactome.org/PathwayBrowser/#/R-SSC-158546 UGTs glucuronate APAP to APAP-GlcA IEA Sus scrofa 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 132962 R-ALL-158604 APAP-GlcA [endoplasmic reticulum lumen] R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 132975 R-ALL-9732936 grazoprevir [cytosol] R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-BTA-1963582 https://reactome.org/PathwayBrowser/#/R-BTA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Bos taurus 132986 R-ALL-9649894 Sapitinib [cytosol] R-BTA-9652264 https://reactome.org/PathwayBrowser/#/R-BTA-9652264 ERBB2 binds TKIs IEA Bos taurus 132986 R-ALL-9649894 Sapitinib [cytosol] R-CEL-1963582 https://reactome.org/PathwayBrowser/#/R-CEL-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Caenorhabditis elegans 132986 R-ALL-9649894 Sapitinib [cytosol] R-CEL-9652264 https://reactome.org/PathwayBrowser/#/R-CEL-9652264 ERBB2 binds TKIs IEA Caenorhabditis elegans 132986 R-ALL-9649894 Sapitinib [cytosol] R-CFA-1963582 https://reactome.org/PathwayBrowser/#/R-CFA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Canis familiaris 132986 R-ALL-9649894 Sapitinib [cytosol] R-CFA-9652264 https://reactome.org/PathwayBrowser/#/R-CFA-9652264 ERBB2 binds TKIs IEA Canis familiaris 132986 R-ALL-9649894 Sapitinib [cytosol] R-DME-1963582 https://reactome.org/PathwayBrowser/#/R-DME-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Drosophila melanogaster 132986 R-ALL-9649894 Sapitinib [cytosol] R-DME-9652264 https://reactome.org/PathwayBrowser/#/R-DME-9652264 ERBB2 binds TKIs IEA Drosophila melanogaster 132986 R-ALL-9649894 Sapitinib [cytosol] R-DRE-1963582 https://reactome.org/PathwayBrowser/#/R-DRE-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Danio rerio 132986 R-ALL-9649894 Sapitinib [cytosol] R-DRE-9652264 https://reactome.org/PathwayBrowser/#/R-DRE-9652264 ERBB2 binds TKIs IEA Danio rerio 132986 R-ALL-9649894 Sapitinib [cytosol] R-GGA-1963582 https://reactome.org/PathwayBrowser/#/R-GGA-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Gallus gallus 132986 R-ALL-9649894 Sapitinib [cytosol] R-GGA-9652264 https://reactome.org/PathwayBrowser/#/R-GGA-9652264 ERBB2 binds TKIs IEA Gallus gallus 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-1248694 https://reactome.org/PathwayBrowser/#/R-HSA-1248694 Trans-autophosphorylation of ERBB2 homodimer TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-1963582 https://reactome.org/PathwayBrowser/#/R-HSA-1963582 Trans-autophosphorylation of ERBB2 heterodimers TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-9652264 https://reactome.org/PathwayBrowser/#/R-HSA-9652264 ERBB2 binds TKIs TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-9664588 https://reactome.org/PathwayBrowser/#/R-HSA-9664588 ERBB2 KD mutants trans-autophosphorylate TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-9665121 https://reactome.org/PathwayBrowser/#/R-HSA-9665121 ERBB2 KD mutants bind TKIs TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-HSA-9665304 https://reactome.org/PathwayBrowser/#/R-HSA-9665304 ERBB2 T862A does not bind sapitinib TAS Homo sapiens 132986 R-ALL-9649894 Sapitinib [cytosol] R-MMU-1963582 https://reactome.org/PathwayBrowser/#/R-MMU-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Mus musculus 132986 R-ALL-9649894 Sapitinib [cytosol] R-MMU-9652264 https://reactome.org/PathwayBrowser/#/R-MMU-9652264 ERBB2 binds TKIs IEA Mus musculus 132986 R-ALL-9649894 Sapitinib [cytosol] R-RNO-1963582 https://reactome.org/PathwayBrowser/#/R-RNO-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Rattus norvegicus 132986 R-ALL-9649894 Sapitinib [cytosol] R-RNO-9652264 https://reactome.org/PathwayBrowser/#/R-RNO-9652264 ERBB2 binds TKIs IEA Rattus norvegicus 132986 R-ALL-9649894 Sapitinib [cytosol] R-SSC-1963582 https://reactome.org/PathwayBrowser/#/R-SSC-1963582 Trans-autophosphorylation of ERBB2 heterodimers IEA Sus scrofa 132986 R-ALL-9649894 Sapitinib [cytosol] R-SSC-9652264 https://reactome.org/PathwayBrowser/#/R-SSC-9652264 ERBB2 binds TKIs IEA Sus scrofa 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-BTA-5617138 https://reactome.org/PathwayBrowser/#/R-BTA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-BTA-9638090 https://reactome.org/PathwayBrowser/#/R-BTA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Bos taurus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-CFA-5617138 https://reactome.org/PathwayBrowser/#/R-CFA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-CFA-9638090 https://reactome.org/PathwayBrowser/#/R-CFA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Canis familiaris 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-DRE-5617138 https://reactome.org/PathwayBrowser/#/R-DRE-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-DRE-9638090 https://reactome.org/PathwayBrowser/#/R-DRE-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Danio rerio 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-HSA-5617138 https://reactome.org/PathwayBrowser/#/R-HSA-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-HSA-9638090 https://reactome.org/PathwayBrowser/#/R-HSA-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA TAS Homo sapiens 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-MMU-5617138 https://reactome.org/PathwayBrowser/#/R-MMU-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-MMU-9638090 https://reactome.org/PathwayBrowser/#/R-MMU-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Mus musculus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-RNO-5617138 https://reactome.org/PathwayBrowser/#/R-RNO-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-RNO-9638090 https://reactome.org/PathwayBrowser/#/R-RNO-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Rattus norvegicus 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-SSC-5617138 https://reactome.org/PathwayBrowser/#/R-SSC-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-SSC-9638090 https://reactome.org/PathwayBrowser/#/R-SSC-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Sus scrofa 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-XTR-5617138 https://reactome.org/PathwayBrowser/#/R-XTR-5617138 B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 133015 R-ALL-8932257 Xyl-GlcA-Xyl-GlcA [Golgi lumen] R-XTR-9638090 https://reactome.org/PathwayBrowser/#/R-XTR-9638090 B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA IEA Xenopus tropicalis 133021 R-ALL-9692345 venetoclax [cytosol] R-BTA-9692376 https://reactome.org/PathwayBrowser/#/R-BTA-9692376 BCL2 binds BCL2 antagonists IEA Bos taurus 133021 R-ALL-9692345 venetoclax [cytosol] R-CEL-9692376 https://reactome.org/PathwayBrowser/#/R-CEL-9692376 BCL2 binds BCL2 antagonists IEA Caenorhabditis elegans 133021 R-ALL-9692345 venetoclax [cytosol] R-CFA-9692376 https://reactome.org/PathwayBrowser/#/R-CFA-9692376 BCL2 binds BCL2 antagonists IEA Canis familiaris 133021 R-ALL-9692345 venetoclax [cytosol] R-DRE-9692376 https://reactome.org/PathwayBrowser/#/R-DRE-9692376 BCL2 binds BCL2 antagonists IEA Danio rerio 133021 R-ALL-9692345 venetoclax [cytosol] R-GGA-9692376 https://reactome.org/PathwayBrowser/#/R-GGA-9692376 BCL2 binds BCL2 antagonists IEA Gallus gallus 133021 R-ALL-9692345 venetoclax [cytosol] R-HSA-9692376 https://reactome.org/PathwayBrowser/#/R-HSA-9692376 BCL2 binds BCL2 antagonists TAS Homo sapiens 133021 R-ALL-9692345 venetoclax [cytosol] R-MMU-9692376 https://reactome.org/PathwayBrowser/#/R-MMU-9692376 BCL2 binds BCL2 antagonists IEA Mus musculus 133021 R-ALL-9692345 venetoclax [cytosol] R-SSC-9692376 https://reactome.org/PathwayBrowser/#/R-SSC-9692376 BCL2 binds BCL2 antagonists IEA Sus scrofa 133021 R-ALL-9692345 venetoclax [cytosol] R-XTR-9692376 https://reactome.org/PathwayBrowser/#/R-XTR-9692376 BCL2 binds BCL2 antagonists IEA Xenopus tropicalis 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133066 R-ALL-9753640 APAP-Cys [extracellular region] R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133067 R-ALL-9753653 APAP-Cys [cytosol] R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133067 R-ALL-9753653 APAP-Cys [cytosol] R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 133067 R-ALL-9753653 APAP-Cys [cytosol] R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133067 R-ALL-9753653 APAP-Cys [cytosol] R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 133067 R-ALL-9753653 APAP-Cys [cytosol] R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 133067 R-ALL-9753653 APAP-Cys [cytosol] R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133067 R-ALL-9753653 APAP-Cys [cytosol] R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 133067 R-ALL-9753653 APAP-Cys [cytosol] R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 133067 R-ALL-9753653 APAP-Cys [cytosol] R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133067 R-ALL-9753653 APAP-Cys [cytosol] R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 133067 R-ALL-9753653 APAP-Cys [cytosol] R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 133067 R-ALL-9753653 APAP-Cys [cytosol] R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133067 R-ALL-9753653 APAP-Cys [cytosol] R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 133134 R-ALL-9028280 PGH3 [cytosol] R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 133134 R-ALL-9028280 PGH3 [cytosol] R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 133134 R-ALL-9028280 PGH3 [cytosol] R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 133134 R-ALL-9028280 PGH3 [cytosol] R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 133134 R-ALL-9028280 PGH3 [cytosol] R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 133134 R-ALL-9028280 PGH3 [cytosol] R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 133134 R-ALL-9028280 PGH3 [cytosol] R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 133134 R-ALL-9028280 PGH3 [cytosol] R-RNO-9028255 https://reactome.org/PathwayBrowser/#/R-RNO-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Rattus norvegicus 133134 R-ALL-9028280 PGH3 [cytosol] R-SSC-9028255 https://reactome.org/PathwayBrowser/#/R-SSC-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Sus scrofa 133134 R-ALL-9028280 PGH3 [cytosol] R-XTR-9028255 https://reactome.org/PathwayBrowser/#/R-XTR-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Xenopus tropicalis 133309 R-ALL-2142810 12-oxoLTB4 [cytosol] R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 133309 R-ALL-2142810 12-oxoLTB4 [cytosol] R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 133334 R-ALL-9833832 snoRNA [cytosol] R-BTA-9833777 https://reactome.org/PathwayBrowser/#/R-BTA-9833777 PKR binds activating host RNA IEA Bos taurus 133334 R-ALL-9833832 snoRNA [cytosol] R-CEL-9833777 https://reactome.org/PathwayBrowser/#/R-CEL-9833777 PKR binds activating host RNA IEA Caenorhabditis elegans 133334 R-ALL-9833832 snoRNA [cytosol] R-CFA-9833777 https://reactome.org/PathwayBrowser/#/R-CFA-9833777 PKR binds activating host RNA IEA Canis familiaris 133334 R-ALL-9833832 snoRNA [cytosol] R-DME-9833777 https://reactome.org/PathwayBrowser/#/R-DME-9833777 PKR binds activating host RNA IEA Drosophila melanogaster 133334 R-ALL-9833832 snoRNA [cytosol] R-DRE-9833777 https://reactome.org/PathwayBrowser/#/R-DRE-9833777 PKR binds activating host RNA IEA Danio rerio 133334 R-ALL-9833832 snoRNA [cytosol] R-GGA-9833777 https://reactome.org/PathwayBrowser/#/R-GGA-9833777 PKR binds activating host RNA IEA Gallus gallus 133334 R-ALL-9833832 snoRNA [cytosol] R-HSA-9833723 https://reactome.org/PathwayBrowser/#/R-HSA-9833723 PKR forms a dimer TAS Homo sapiens 133334 R-ALL-9833832 snoRNA [cytosol] R-HSA-9833777 https://reactome.org/PathwayBrowser/#/R-HSA-9833777 PKR binds activating host RNA TAS Homo sapiens 133334 R-ALL-9833832 snoRNA [cytosol] R-MMU-9833777 https://reactome.org/PathwayBrowser/#/R-MMU-9833777 PKR binds activating host RNA IEA Mus musculus 133334 R-ALL-9833832 snoRNA [cytosol] R-RNO-9833777 https://reactome.org/PathwayBrowser/#/R-RNO-9833777 PKR binds activating host RNA IEA Rattus norvegicus 133334 R-ALL-9833832 snoRNA [cytosol] R-SSC-9833777 https://reactome.org/PathwayBrowser/#/R-SSC-9833777 PKR binds activating host RNA IEA Sus scrofa 133334 R-ALL-9833832 snoRNA [cytosol] R-XTR-9833777 https://reactome.org/PathwayBrowser/#/R-XTR-9833777 PKR binds activating host RNA IEA Xenopus tropicalis 133367 R-ALL-9024760 RvD2 [cytosol] R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 133367 R-ALL-9024760 RvD2 [cytosol] R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 133367 R-ALL-9024760 RvD2 [cytosol] R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 133367 R-ALL-9024760 RvD2 [cytosol] R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 133367 R-ALL-9024760 RvD2 [cytosol] R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 133367 R-ALL-9024760 RvD2 [cytosol] R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 133367 R-ALL-9024760 RvD2 [cytosol] R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 133367 R-ALL-9024760 RvD2 [cytosol] R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 133367 R-ALL-9024760 RvD2 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 133367 R-ALL-9024782 RvD2 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 133367 R-ALL-9024760 RvD2 [cytosol] R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 133367 R-ALL-9024760 RvD2 [cytosol] R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 133367 R-ALL-9024760 RvD2 [cytosol] R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 133367 R-ALL-9024760 RvD2 [cytosol] R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 133367 R-ALL-9024760 RvD2 [cytosol] R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 133367 R-ALL-9024760 RvD2 [cytosol] R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 133368 R-ALL-9023700 18(R)-RvE2 [cytosol] R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 TAS Homo sapiens 133368 R-ALL-9023700 18(R)-RvE2 [cytosol] R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 133368 R-ALL-9023989 18(R)-RvE2 [extracellular region] R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 133370 R-ALL-2299726 PGA2 [cytosol] R-HSA-2161659 https://reactome.org/PathwayBrowser/#/R-HSA-2161659 PGE2 is dehydrated to PGA2 TAS Homo sapiens 133370 R-ALL-2299726 PGA2 [cytosol] R-HSA-2161666 https://reactome.org/PathwayBrowser/#/R-HSA-2161666 PGA2 is isomerised to PGC2 TAS Homo sapiens 133370 R-ALL-2299726 PGA2 [cytosol] R-HSA-2161668 https://reactome.org/PathwayBrowser/#/R-HSA-2161668 PGA2 is dehydrated to 15d-PGA2 IEA Homo sapiens 133370 R-ALL-2142755 PGA2 [endoplasmic reticulum lumen] R-MMU-2161646 https://reactome.org/PathwayBrowser/#/R-MMU-2161646 PGA2 is dehydrated to 15d-PGA2 TAS Mus musculus 133374 R-ALL-2142751 dhk-PGF2a [cytosol] R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 133374 R-ALL-2142751 dhk-PGF2a [cytosol] R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 133391 R-ALL-2299721 PGB2 [cytosol] R-HSA-2161735 https://reactome.org/PathwayBrowser/#/R-HSA-2161735 PGC2 is isomerised to PGB2 TAS Homo sapiens 133392 R-ALL-2299724 PGC2 [cytosol] R-HSA-2161666 https://reactome.org/PathwayBrowser/#/R-HSA-2161666 PGA2 is isomerised to PGC2 TAS Homo sapiens 133392 R-ALL-2299724 PGC2 [cytosol] R-HSA-2161735 https://reactome.org/PathwayBrowser/#/R-HSA-2161735 PGC2 is isomerised to PGB2 TAS Homo sapiens 133396 R-ALL-2142674 PGJ2 [endoplasmic reticulum lumen] R-HSA-2161563 https://reactome.org/PathwayBrowser/#/R-HSA-2161563 PGJ2 is isomerised to delta12-PGJ2 TAS Homo sapiens 133396 R-ALL-2142674 PGJ2 [endoplasmic reticulum lumen] R-HSA-2161733 https://reactome.org/PathwayBrowser/#/R-HSA-2161733 PGD2 is dehydrated to PGJ2 TAS Homo sapiens 133409 R-ALL-2142799 15k-PGF2a [cytosol] R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 133409 R-ALL-2142799 15k-PGF2a [cytosol] R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 133409 R-ALL-2142799 15k-PGF2a [cytosol] R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 133409 R-ALL-2142799 15k-PGF2a [cytosol] R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 133424 R-ALL-2142821 delta12-PGJ2 [endoplasmic reticulum lumen] R-HSA-2161563 https://reactome.org/PathwayBrowser/#/R-HSA-2161563 PGJ2 is isomerised to delta12-PGJ2 TAS Homo sapiens 133424 R-ALL-2142821 delta12-PGJ2 [endoplasmic reticulum lumen] R-HSA-2161588 https://reactome.org/PathwayBrowser/#/R-HSA-2161588 Delta12-PGJ2 is dehydrated to 15d-PGJ2 TAS Homo sapiens 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133435 R-ALL-9753665 APAP-Mer [extracellular region] R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133438 R-ALL-9753642 APAP-Mer [cytosol] R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-BTA-9753676 https://reactome.org/PathwayBrowser/#/R-BTA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Bos taurus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 133438 R-ALL-9753642 APAP-Mer [cytosol] R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 133438 R-ALL-9753642 APAP-Mer [cytosol] R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 133438 R-ALL-9753642 APAP-Mer [cytosol] R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 133438 R-ALL-9753642 APAP-Mer [cytosol] R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 133438 R-ALL-9753642 APAP-Mer [cytosol] R-DRE-9753676 https://reactome.org/PathwayBrowser/#/R-DRE-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Danio rerio 133438 R-ALL-9753642 APAP-Mer [cytosol] R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-GGA-9753676 https://reactome.org/PathwayBrowser/#/R-GGA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Gallus gallus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 133438 R-ALL-9753642 APAP-Mer [cytosol] R-HSA-9753676 https://reactome.org/PathwayBrowser/#/R-HSA-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer TAS Homo sapiens 133438 R-ALL-9753642 APAP-Mer [cytosol] R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-MMU-9753676 https://reactome.org/PathwayBrowser/#/R-MMU-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Mus musculus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 133438 R-ALL-9753642 APAP-Mer [cytosol] R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-RNO-9753676 https://reactome.org/PathwayBrowser/#/R-RNO-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Rattus norvegicus 133438 R-ALL-9753642 APAP-Mer [cytosol] R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 133438 R-ALL-9753642 APAP-Mer [cytosol] R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 133438 R-ALL-9753642 APAP-Mer [cytosol] R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 133438 R-ALL-9753642 APAP-Mer [cytosol] R-SSC-9753676 https://reactome.org/PathwayBrowser/#/R-SSC-9753676 NAT1,2 acetylate APAP-Cys to APAP-Mer IEA Sus scrofa 133438 R-ALL-9753642 APAP-Mer [cytosol] R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 133451 R-ALL-2142786 6k-PGF1a [endoplasmic reticulum lumen] R-HSA-2161619 https://reactome.org/PathwayBrowser/#/R-HSA-2161619 PGI2 is hydrolysed to 6k-PGF1a TAS Homo sapiens 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-CFA-8941701 https://reactome.org/PathwayBrowser/#/R-CFA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Canis familiaris 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-DDI-8941701 https://reactome.org/PathwayBrowser/#/R-DDI-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Dictyostelium discoideum 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-GGA-8941701 https://reactome.org/PathwayBrowser/#/R-GGA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Gallus gallus 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-HSA-8941701 https://reactome.org/PathwayBrowser/#/R-HSA-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN TAS Homo sapiens 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-MMU-8941701 https://reactome.org/PathwayBrowser/#/R-MMU-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Mus musculus 133667 R-ALL-8941725 GCTN4OG [endoplasmic reticulum lumen] R-RNO-8941701 https://reactome.org/PathwayBrowser/#/R-RNO-8941701 UGT1A10 transfers GlcA from UDP-GlcA to GCTN IEA Rattus norvegicus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-BTA-9020275 https://reactome.org/PathwayBrowser/#/R-BTA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Bos taurus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-CFA-9020275 https://reactome.org/PathwayBrowser/#/R-CFA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Canis familiaris 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DDI-9020275 https://reactome.org/PathwayBrowser/#/R-DDI-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Dictyostelium discoideum 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DRE-9020275 https://reactome.org/PathwayBrowser/#/R-DRE-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Danio rerio 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-HSA-9020275 https://reactome.org/PathwayBrowser/#/R-HSA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA TAS Homo sapiens 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-MMU-9020275 https://reactome.org/PathwayBrowser/#/R-MMU-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Mus musculus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-RNO-9020275 https://reactome.org/PathwayBrowser/#/R-RNO-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Rattus norvegicus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-RNO-9024872 https://reactome.org/PathwayBrowser/#/R-RNO-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Rattus norvegicus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-SSC-9020275 https://reactome.org/PathwayBrowser/#/R-SSC-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Sus scrofa 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-SSC-9024872 https://reactome.org/PathwayBrowser/#/R-SSC-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Sus scrofa 133795 R-ALL-9024012 17(S)-Hp-DHA [cytosol] R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-RNO-9027607 https://reactome.org/PathwayBrowser/#/R-RNO-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Rattus norvegicus 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-SSC-9027607 https://reactome.org/PathwayBrowser/#/R-SSC-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Sus scrofa 133797 R-ALL-9027614 17-HDPAn-3 [cytosol] R-XTR-9027607 https://reactome.org/PathwayBrowser/#/R-XTR-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Xenopus tropicalis 133817 R-ALL-8937418 DOXOL [cytosol] R-BTA-8937419 https://reactome.org/PathwayBrowser/#/R-BTA-8937419 CBR3 reduces DOX to DOXOL IEA Bos taurus 133817 R-ALL-8937418 DOXOL [cytosol] R-CFA-8937419 https://reactome.org/PathwayBrowser/#/R-CFA-8937419 CBR3 reduces DOX to DOXOL IEA Canis familiaris 133817 R-ALL-8937418 DOXOL [cytosol] R-DRE-8937419 https://reactome.org/PathwayBrowser/#/R-DRE-8937419 CBR3 reduces DOX to DOXOL IEA Danio rerio 133817 R-ALL-8937418 DOXOL [cytosol] R-GGA-8937419 https://reactome.org/PathwayBrowser/#/R-GGA-8937419 CBR3 reduces DOX to DOXOL IEA Gallus gallus 133817 R-ALL-8937418 DOXOL [cytosol] R-HSA-8937419 https://reactome.org/PathwayBrowser/#/R-HSA-8937419 CBR3 reduces DOX to DOXOL TAS Homo sapiens 133817 R-ALL-8937418 DOXOL [cytosol] R-MMU-8937419 https://reactome.org/PathwayBrowser/#/R-MMU-8937419 CBR3 reduces DOX to DOXOL IEA Mus musculus 133817 R-ALL-8937418 DOXOL [cytosol] R-RNO-8937419 https://reactome.org/PathwayBrowser/#/R-RNO-8937419 CBR3 reduces DOX to DOXOL IEA Rattus norvegicus 133817 R-ALL-8937418 DOXOL [cytosol] R-SSC-8937419 https://reactome.org/PathwayBrowser/#/R-SSC-8937419 CBR3 reduces DOX to DOXOL IEA Sus scrofa 133817 R-ALL-8937418 DOXOL [cytosol] R-XTR-8937419 https://reactome.org/PathwayBrowser/#/R-XTR-8937419 CBR3 reduces DOX to DOXOL IEA Xenopus tropicalis 133907 R-ALL-8855489 OSCN- [extracellular region] R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 133907 R-ALL-8855489 OSCN- [extracellular region] R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 133907 R-ALL-8855489 OSCN- [extracellular region] R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 133907 R-ALL-8855489 OSCN- [extracellular region] R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 133907 R-ALL-8855489 OSCN- [extracellular region] R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 133907 R-ALL-8855489 OSCN- [extracellular region] R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 133907 R-ALL-8855489 OSCN- [extracellular region] R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 133907 R-ALL-8855489 OSCN- [extracellular region] R-HSA-8941411 https://reactome.org/PathwayBrowser/#/R-HSA-8941411 OSCN- reacts with Cys residues TAS Homo sapiens 133907 R-ALL-8855489 OSCN- [extracellular region] R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 133907 R-ALL-8855489 OSCN- [extracellular region] R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 133907 R-ALL-8855489 OSCN- [extracellular region] R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-BTA-176588 https://reactome.org/PathwayBrowser/#/R-BTA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Bos taurus 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-DME-176588 https://reactome.org/PathwayBrowser/#/R-DME-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Drosophila melanogaster 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-DRE-176588 https://reactome.org/PathwayBrowser/#/R-DRE-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Danio rerio 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-GGA-176588 https://reactome.org/PathwayBrowser/#/R-GGA-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Gallus gallus 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-HSA-176588 https://reactome.org/PathwayBrowser/#/R-HSA-176588 lithocholate + PAPS => lithocholate sulfate + PAP TAS Homo sapiens 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-MMU-176588 https://reactome.org/PathwayBrowser/#/R-MMU-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Mus musculus 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-RNO-176588 https://reactome.org/PathwayBrowser/#/R-RNO-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Rattus norvegicus 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-SSC-176588 https://reactome.org/PathwayBrowser/#/R-SSC-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Sus scrofa 133940 R-ALL-176555 lithocholate sulfate [cytosol] R-XTR-176588 https://reactome.org/PathwayBrowser/#/R-XTR-176588 lithocholate + PAPS => lithocholate sulfate + PAP IEA Xenopus tropicalis 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 133969 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 133969 R-COV-9685914 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 133969 R-COV-9685920 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 133969 R-COV-9685916 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 133969 R-COV-9685917 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 133969 R-COV-9685921 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 133969 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 133969 R-COV-9684636 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 133969 R-COV-9685890 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685889 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685888 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685894 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685893 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685887 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685886 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685885 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 133969 R-COV-9684636 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 133969 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9685597 https://reactome.org/PathwayBrowser/#/R-HSA-9685597 RTC binds SARS-CoV-1 genomic RNA complement (minus strand) TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 133969 R-COV-9685921 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685914 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685916 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685920 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685917 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685890 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685889 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685888 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685894 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685893 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685887 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685886 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685885 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685922 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685915 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685918 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 133969 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 133969 R-COV-9694622 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 133969 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 133969 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 133969 R-COV-9694503 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 133969 R-COV-9694619 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 133969 R-COV-9792628 GpppAm-mRNA5 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792630 GpppAm-mRNA4 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792624 GpppAm-mRNA9 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792637 GpppAm-mRNA3 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792638 GpppAm-mRNA6 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792622 GpppAm-mRNA8 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792633 GpppAm-mRNA7 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9792632 GpppAm-mRNA2 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 133969 R-COV-9694352 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694710 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694613 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694757 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694699 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694523 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694266 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694350 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 133969 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 133969 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 133969 R-COV-9694456 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 133969 R-COV-9694619 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 133969 R-COV-9694325 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694352 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694710 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694613 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694757 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694699 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694523 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694266 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694350 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694354 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694496 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694503 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694456 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694622 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694285 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 133969 R-COV-9694325 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 133969 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 133969 R-COV-9694285 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 133969 R-COV-9694496 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 133969 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 133969 R-COV-9694354 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 133969 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 133969 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 133969 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 133969 R-COV-9792628 GpppAm-mRNA5 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792630 GpppAm-mRNA4 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792624 GpppAm-mRNA9 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792637 GpppAm-mRNA3 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792638 GpppAm-mRNA6 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792622 GpppAm-mRNA8 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792633 GpppAm-mRNA7 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133969 R-COV-9792632 GpppAm-mRNA2 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 133975 R-ALL-2142669 6t,12epi-LTB4 [cytosol] R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 133977 R-ALL-176056 DNPSG [cytosol] R-BTA-176054 https://reactome.org/PathwayBrowser/#/R-BTA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Bos taurus 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-BTA-3301943 https://reactome.org/PathwayBrowser/#/R-BTA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Bos taurus 133977 R-ALL-176056 DNPSG [cytosol] R-CEL-176054 https://reactome.org/PathwayBrowser/#/R-CEL-176054 GST dimers conjugate GSH with cytosolic substrates IEA Caenorhabditis elegans 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-CEL-3301943 https://reactome.org/PathwayBrowser/#/R-CEL-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Caenorhabditis elegans 133977 R-ALL-176056 DNPSG [cytosol] R-CFA-176054 https://reactome.org/PathwayBrowser/#/R-CFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Canis familiaris 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-CFA-3301943 https://reactome.org/PathwayBrowser/#/R-CFA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Canis familiaris 133977 R-ALL-176056 DNPSG [cytosol] R-DDI-176054 https://reactome.org/PathwayBrowser/#/R-DDI-176054 GST dimers conjugate GSH with cytosolic substrates IEA Dictyostelium discoideum 133977 R-ALL-176056 DNPSG [cytosol] R-DME-176054 https://reactome.org/PathwayBrowser/#/R-DME-176054 GST dimers conjugate GSH with cytosolic substrates IEA Drosophila melanogaster 133977 R-ALL-176056 DNPSG [cytosol] R-DRE-176054 https://reactome.org/PathwayBrowser/#/R-DRE-176054 GST dimers conjugate GSH with cytosolic substrates IEA Danio rerio 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-DRE-3301943 https://reactome.org/PathwayBrowser/#/R-DRE-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Danio rerio 133977 R-ALL-176056 DNPSG [cytosol] R-GGA-176054 https://reactome.org/PathwayBrowser/#/R-GGA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Gallus gallus 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-GGA-3301943 https://reactome.org/PathwayBrowser/#/R-GGA-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Gallus gallus 133977 R-ALL-176056 DNPSG [cytosol] R-HSA-176054 https://reactome.org/PathwayBrowser/#/R-HSA-176054 GST dimers conjugate GSH with cytosolic substrates TAS Homo sapiens 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-HSA-3301943 https://reactome.org/PathwayBrowser/#/R-HSA-3301943 GSTK1 dimer transfers GS from GSH to CDNB TAS Homo sapiens 133977 R-ALL-176056 DNPSG [cytosol] R-MMU-176054 https://reactome.org/PathwayBrowser/#/R-MMU-176054 GST dimers conjugate GSH with cytosolic substrates IEA Mus musculus 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-MMU-3301943 https://reactome.org/PathwayBrowser/#/R-MMU-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Mus musculus 133977 R-ALL-176056 DNPSG [cytosol] R-PFA-176054 https://reactome.org/PathwayBrowser/#/R-PFA-176054 GST dimers conjugate GSH with cytosolic substrates IEA Plasmodium falciparum 133977 R-ALL-176056 DNPSG [cytosol] R-RNO-176054 https://reactome.org/PathwayBrowser/#/R-RNO-176054 GST dimers conjugate GSH with cytosolic substrates IEA Rattus norvegicus 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-RNO-3301943 https://reactome.org/PathwayBrowser/#/R-RNO-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Rattus norvegicus 133977 R-ALL-176056 DNPSG [cytosol] R-SSC-176054 https://reactome.org/PathwayBrowser/#/R-SSC-176054 GST dimers conjugate GSH with cytosolic substrates IEA Sus scrofa 133977 R-ALL-3301969 DNPSG [mitochondrial matrix] R-SSC-3301943 https://reactome.org/PathwayBrowser/#/R-SSC-3301943 GSTK1 dimer transfers GS from GSH to CDNB IEA Sus scrofa 133977 R-ALL-176056 DNPSG [cytosol] R-XTR-176054 https://reactome.org/PathwayBrowser/#/R-XTR-176054 GST dimers conjugate GSH with cytosolic substrates IEA Xenopus tropicalis 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 134020 R-ALL-9673044 oleoyl-Phe [extracellular region] R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 134117 R-ALL-8952135 presqualene monophosphate [cytosol] R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 134401 R-ALL-8960276 glucanotrehalose [cytosol] R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 134401 R-ALL-8960276 glucanotrehalose [cytosol] R-MTU-868658 https://reactome.org/PathwayBrowser/#/R-MTU-868658 1,4-alpha-glucan is converted to glucanotrehalose TAS Mycobacterium tuberculosis 134656 R-ALL-9026417 RvT1 [cytosol] R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 134656 R-ALL-9026417 RvT1 [cytosol] R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 134656 R-ALL-9026417 RvT1 [cytosol] R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 134656 R-ALL-9026417 RvT1 [cytosol] R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 134656 R-ALL-9026417 RvT1 [cytosol] R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 134656 R-ALL-9026417 RvT1 [cytosol] R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 134656 R-ALL-9026417 RvT1 [cytosol] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134656 R-ALL-9032023 RvT1 [extracellular region] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134656 R-ALL-9026417 RvT1 [cytosol] R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 134656 R-ALL-9026417 RvT1 [cytosol] R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 134656 R-ALL-9026417 RvT1 [cytosol] R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 134656 R-ALL-9026417 RvT1 [cytosol] R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 134657 R-ALL-9026401 RvT2 [cytosol] R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 134657 R-ALL-9026401 RvT2 [cytosol] R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 134657 R-ALL-9026401 RvT2 [cytosol] R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 134657 R-ALL-9026401 RvT2 [cytosol] R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 134657 R-ALL-9026401 RvT2 [cytosol] R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 134657 R-ALL-9026401 RvT2 [cytosol] R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 134657 R-ALL-9026401 RvT2 [cytosol] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134657 R-ALL-9032018 RvT2 [extracellular region] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134657 R-ALL-9026401 RvT2 [cytosol] R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 134657 R-ALL-9026401 RvT2 [cytosol] R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 134657 R-ALL-9026401 RvT2 [cytosol] R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 134657 R-ALL-9026401 RvT2 [cytosol] R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 134658 R-ALL-9026419 RvT3 [cytosol] R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 134658 R-ALL-9026419 RvT3 [cytosol] R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 134658 R-ALL-9026419 RvT3 [cytosol] R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 134658 R-ALL-9026419 RvT3 [cytosol] R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 134658 R-ALL-9026419 RvT3 [cytosol] R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 134658 R-ALL-9026419 RvT3 [cytosol] R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 134658 R-ALL-9026419 RvT3 [cytosol] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134658 R-ALL-9032019 RvT3 [extracellular region] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134658 R-ALL-9026419 RvT3 [cytosol] R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 134658 R-ALL-9026419 RvT3 [cytosol] R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 134658 R-ALL-9026419 RvT3 [cytosol] R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 134658 R-ALL-9026419 RvT3 [cytosol] R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 134659 R-ALL-9026398 RvT4 [cytosol] R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 134659 R-ALL-9026398 RvT4 [cytosol] R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 134659 R-ALL-9026398 RvT4 [cytosol] R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 134659 R-ALL-9026398 RvT4 [cytosol] R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 134659 R-ALL-9026398 RvT4 [cytosol] R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 134659 R-ALL-9026398 RvT4 [cytosol] R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 134659 R-ALL-9026398 RvT4 [cytosol] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134659 R-ALL-9032024 RvT4 [extracellular region] R-HSA-9032021 https://reactome.org/PathwayBrowser/#/R-HSA-9032021 RvT1-4 translocate from cytosol to extracellular region TAS Homo sapiens 134659 R-ALL-9026398 RvT4 [cytosol] R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 134659 R-ALL-9026398 RvT4 [cytosol] R-RNO-9026405 https://reactome.org/PathwayBrowser/#/R-RNO-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Rattus norvegicus 134659 R-ALL-9026398 RvT4 [cytosol] R-SSC-9026405 https://reactome.org/PathwayBrowser/#/R-SSC-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Sus scrofa 134659 R-ALL-9026398 RvT4 [cytosol] R-XTR-9026405 https://reactome.org/PathwayBrowser/#/R-XTR-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Xenopus tropicalis 134677 R-ALL-9708253 crisaborole [cytosol] R-BTA-9708275 https://reactome.org/PathwayBrowser/#/R-BTA-9708275 PDE4A binds PDE4A inhibitors IEA Bos taurus 134677 R-ALL-9708253 crisaborole [cytosol] R-CEL-9708275 https://reactome.org/PathwayBrowser/#/R-CEL-9708275 PDE4A binds PDE4A inhibitors IEA Caenorhabditis elegans 134677 R-ALL-9708253 crisaborole [cytosol] R-CFA-9708275 https://reactome.org/PathwayBrowser/#/R-CFA-9708275 PDE4A binds PDE4A inhibitors IEA Canis familiaris 134677 R-ALL-9708253 crisaborole [cytosol] R-DDI-9708275 https://reactome.org/PathwayBrowser/#/R-DDI-9708275 PDE4A binds PDE4A inhibitors IEA Dictyostelium discoideum 134677 R-ALL-9708253 crisaborole [cytosol] R-DME-9708275 https://reactome.org/PathwayBrowser/#/R-DME-9708275 PDE4A binds PDE4A inhibitors IEA Drosophila melanogaster 134677 R-ALL-9708253 crisaborole [cytosol] R-HSA-9708275 https://reactome.org/PathwayBrowser/#/R-HSA-9708275 PDE4A binds PDE4A inhibitors TAS Homo sapiens 134677 R-ALL-9708253 crisaborole [cytosol] R-MMU-9708275 https://reactome.org/PathwayBrowser/#/R-MMU-9708275 PDE4A binds PDE4A inhibitors IEA Mus musculus 134677 R-ALL-9708253 crisaborole [cytosol] R-PFA-9708275 https://reactome.org/PathwayBrowser/#/R-PFA-9708275 PDE4A binds PDE4A inhibitors IEA Plasmodium falciparum 134677 R-ALL-9708253 crisaborole [cytosol] R-RNO-9708275 https://reactome.org/PathwayBrowser/#/R-RNO-9708275 PDE4A binds PDE4A inhibitors IEA Rattus norvegicus 134677 R-ALL-9708253 crisaborole [cytosol] R-SSC-9708275 https://reactome.org/PathwayBrowser/#/R-SSC-9708275 PDE4A binds PDE4A inhibitors IEA Sus scrofa 134677 R-ALL-9708253 crisaborole [cytosol] R-XTR-9708275 https://reactome.org/PathwayBrowser/#/R-XTR-9708275 PDE4A binds PDE4A inhibitors IEA Xenopus tropicalis 134699 R-ALL-9679750 opicapone [extracellular region] R-BTA-379387 https://reactome.org/PathwayBrowser/#/R-BTA-379387 COMT transfers Met to DA to form 3MT IEA Bos taurus 134699 R-ALL-9679750 opicapone [extracellular region] R-BTA-9679775 https://reactome.org/PathwayBrowser/#/R-BTA-9679775 COMT binds COMT Inhibitors IEA Bos taurus 134699 R-ALL-9679750 opicapone [extracellular region] R-CFA-379387 https://reactome.org/PathwayBrowser/#/R-CFA-379387 COMT transfers Met to DA to form 3MT IEA Canis familiaris 134699 R-ALL-9679750 opicapone [extracellular region] R-CFA-9679775 https://reactome.org/PathwayBrowser/#/R-CFA-9679775 COMT binds COMT Inhibitors IEA Canis familiaris 134699 R-ALL-9679750 opicapone [extracellular region] R-DRE-379387 https://reactome.org/PathwayBrowser/#/R-DRE-379387 COMT transfers Met to DA to form 3MT IEA Danio rerio 134699 R-ALL-9679750 opicapone [extracellular region] R-DRE-9679775 https://reactome.org/PathwayBrowser/#/R-DRE-9679775 COMT binds COMT Inhibitors IEA Danio rerio 134699 R-ALL-9679750 opicapone [extracellular region] R-GGA-379387 https://reactome.org/PathwayBrowser/#/R-GGA-379387 COMT transfers Met to DA to form 3MT IEA Gallus gallus 134699 R-ALL-9679750 opicapone [extracellular region] R-GGA-9679775 https://reactome.org/PathwayBrowser/#/R-GGA-9679775 COMT binds COMT Inhibitors IEA Gallus gallus 134699 R-ALL-9679750 opicapone [extracellular region] R-HSA-379387 https://reactome.org/PathwayBrowser/#/R-HSA-379387 COMT transfers Met to DA to form 3MT TAS Homo sapiens 134699 R-ALL-9679750 opicapone [extracellular region] R-HSA-9679775 https://reactome.org/PathwayBrowser/#/R-HSA-9679775 COMT binds COMT Inhibitors TAS Homo sapiens 134699 R-ALL-9679750 opicapone [extracellular region] R-MMU-379387 https://reactome.org/PathwayBrowser/#/R-MMU-379387 COMT transfers Met to DA to form 3MT IEA Mus musculus 134699 R-ALL-9679750 opicapone [extracellular region] R-MMU-9679775 https://reactome.org/PathwayBrowser/#/R-MMU-9679775 COMT binds COMT Inhibitors IEA Mus musculus 134699 R-ALL-9679750 opicapone [extracellular region] R-RNO-379387 https://reactome.org/PathwayBrowser/#/R-RNO-379387 COMT transfers Met to DA to form 3MT IEA Rattus norvegicus 134699 R-ALL-9679750 opicapone [extracellular region] R-RNO-9679775 https://reactome.org/PathwayBrowser/#/R-RNO-9679775 COMT binds COMT Inhibitors IEA Rattus norvegicus 134699 R-ALL-9679750 opicapone [extracellular region] R-SPO-379387 https://reactome.org/PathwayBrowser/#/R-SPO-379387 COMT transfers Met to DA to form 3MT IEA Schizosaccharomyces pombe 134699 R-ALL-9679750 opicapone [extracellular region] R-SPO-9679775 https://reactome.org/PathwayBrowser/#/R-SPO-9679775 COMT binds COMT Inhibitors IEA Schizosaccharomyces pombe 134699 R-ALL-9679750 opicapone [extracellular region] R-SSC-379387 https://reactome.org/PathwayBrowser/#/R-SSC-379387 COMT transfers Met to DA to form 3MT IEA Sus scrofa 134699 R-ALL-9679750 opicapone [extracellular region] R-SSC-9679775 https://reactome.org/PathwayBrowser/#/R-SSC-9679775 COMT binds COMT Inhibitors IEA Sus scrofa 134699 R-ALL-9679750 opicapone [extracellular region] R-XTR-379387 https://reactome.org/PathwayBrowser/#/R-XTR-379387 COMT transfers Met to DA to form 3MT IEA Xenopus tropicalis 134699 R-ALL-9679750 opicapone [extracellular region] R-XTR-9679775 https://reactome.org/PathwayBrowser/#/R-XTR-9679775 COMT binds COMT Inhibitors IEA Xenopus tropicalis 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-BTA-9703895 https://reactome.org/PathwayBrowser/#/R-BTA-9703895 CASR binds CASR agonists IEA Bos taurus 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-CFA-9703895 https://reactome.org/PathwayBrowser/#/R-CFA-9703895 CASR binds CASR agonists IEA Canis familiaris 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-GGA-9703895 https://reactome.org/PathwayBrowser/#/R-GGA-9703895 CASR binds CASR agonists IEA Gallus gallus 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-HSA-9703895 https://reactome.org/PathwayBrowser/#/R-HSA-9703895 CASR binds CASR agonists TAS Homo sapiens 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-MMU-9703895 https://reactome.org/PathwayBrowser/#/R-MMU-9703895 CASR binds CASR agonists IEA Mus musculus 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-RNO-9703895 https://reactome.org/PathwayBrowser/#/R-RNO-9703895 CASR binds CASR agonists IEA Rattus norvegicus 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-SSC-9703895 https://reactome.org/PathwayBrowser/#/R-SSC-9703895 CASR binds CASR agonists IEA Sus scrofa 134700 R-ALL-9703842 etelcalcetide [extracellular region] R-XTR-9703895 https://reactome.org/PathwayBrowser/#/R-XTR-9703895 CASR binds CASR agonists IEA Xenopus tropicalis 134709 R-ALL-9692536 pitolisant [extracellular region] R-BTA-9692867 https://reactome.org/PathwayBrowser/#/R-BTA-9692867 HRH3 binds pitosilant IEA Bos taurus 134709 R-ALL-9692536 pitolisant [extracellular region] R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 134709 R-ALL-9692536 pitolisant [extracellular region] R-CEL-9692867 https://reactome.org/PathwayBrowser/#/R-CEL-9692867 HRH3 binds pitosilant IEA Caenorhabditis elegans 134709 R-ALL-9692536 pitolisant [extracellular region] R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 134709 R-ALL-9692536 pitolisant [extracellular region] R-CFA-9692867 https://reactome.org/PathwayBrowser/#/R-CFA-9692867 HRH3 binds pitosilant IEA Canis familiaris 134709 R-ALL-9692536 pitolisant [extracellular region] R-DME-9692867 https://reactome.org/PathwayBrowser/#/R-DME-9692867 HRH3 binds pitosilant IEA Drosophila melanogaster 134709 R-ALL-9692536 pitolisant [extracellular region] R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 134709 R-ALL-9692536 pitolisant [extracellular region] R-GGA-9692867 https://reactome.org/PathwayBrowser/#/R-GGA-9692867 HRH3 binds pitosilant IEA Gallus gallus 134709 R-ALL-9692536 pitolisant [extracellular region] R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 134709 R-ALL-9692536 pitolisant [extracellular region] R-HSA-9692867 https://reactome.org/PathwayBrowser/#/R-HSA-9692867 HRH3 binds pitosilant TAS Homo sapiens 134709 R-ALL-9692536 pitolisant [extracellular region] R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 134709 R-ALL-9692536 pitolisant [extracellular region] R-MMU-9692867 https://reactome.org/PathwayBrowser/#/R-MMU-9692867 HRH3 binds pitosilant IEA Mus musculus 134709 R-ALL-9692536 pitolisant [extracellular region] R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 134709 R-ALL-9692536 pitolisant [extracellular region] R-RNO-9692867 https://reactome.org/PathwayBrowser/#/R-RNO-9692867 HRH3 binds pitosilant IEA Rattus norvegicus 134709 R-ALL-9692536 pitolisant [extracellular region] R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 134709 R-ALL-9692536 pitolisant [extracellular region] R-SSC-9692867 https://reactome.org/PathwayBrowser/#/R-SSC-9692867 HRH3 binds pitosilant IEA Sus scrofa 134709 R-ALL-9692536 pitolisant [extracellular region] R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 134714 R-ALL-9727597 sacubitril [cytosol] R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 134714 R-ALL-9727597 sacubitril [cytosol] R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 134714 R-ALL-9727597 sacubitril [cytosol] R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 134714 R-ALL-9727597 sacubitril [cytosol] R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 134714 R-ALL-9727597 sacubitril [cytosol] R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 134714 R-ALL-9727597 sacubitril [cytosol] R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 134714 R-ALL-9727597 sacubitril [cytosol] R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 134714 R-ALL-9727597 sacubitril [cytosol] R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 134714 R-ALL-9727597 sacubitril [cytosol] R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 134714 R-ALL-9727597 sacubitril [cytosol] R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 134714 R-ALL-9727597 sacubitril [cytosol] R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 134714 R-ALL-9727597 sacubitril [cytosol] R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 134718 R-ALL-9677953 safinamide [cytosol] R-BTA-9677929 https://reactome.org/PathwayBrowser/#/R-BTA-9677929 MAOB inhibitors bind MAOB:FAD IEA Bos taurus 134718 R-ALL-9677953 safinamide [cytosol] R-CFA-9677929 https://reactome.org/PathwayBrowser/#/R-CFA-9677929 MAOB inhibitors bind MAOB:FAD IEA Canis familiaris 134718 R-ALL-9677953 safinamide [cytosol] R-DDI-9677929 https://reactome.org/PathwayBrowser/#/R-DDI-9677929 MAOB inhibitors bind MAOB:FAD IEA Dictyostelium discoideum 134718 R-ALL-9677953 safinamide [cytosol] R-DRE-9677929 https://reactome.org/PathwayBrowser/#/R-DRE-9677929 MAOB inhibitors bind MAOB:FAD IEA Danio rerio 134718 R-ALL-9677953 safinamide [cytosol] R-GGA-9677929 https://reactome.org/PathwayBrowser/#/R-GGA-9677929 MAOB inhibitors bind MAOB:FAD IEA Gallus gallus 134718 R-ALL-9677953 safinamide [cytosol] R-HSA-9677929 https://reactome.org/PathwayBrowser/#/R-HSA-9677929 MAOB inhibitors bind MAOB:FAD TAS Homo sapiens 134718 R-ALL-9677953 safinamide [cytosol] R-MMU-9677929 https://reactome.org/PathwayBrowser/#/R-MMU-9677929 MAOB inhibitors bind MAOB:FAD IEA Mus musculus 134718 R-ALL-9677953 safinamide [cytosol] R-RNO-9677929 https://reactome.org/PathwayBrowser/#/R-RNO-9677929 MAOB inhibitors bind MAOB:FAD IEA Rattus norvegicus 134718 R-ALL-9677953 safinamide [cytosol] R-SSC-9677929 https://reactome.org/PathwayBrowser/#/R-SSC-9677929 MAOB inhibitors bind MAOB:FAD IEA Sus scrofa 134718 R-ALL-9677953 safinamide [cytosol] R-XTR-9677929 https://reactome.org/PathwayBrowser/#/R-XTR-9677929 MAOB inhibitors bind MAOB:FAD IEA Xenopus tropicalis 134723 R-ALL-9732261 asunaprevir [cytosol] R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 134724 R-ALL-9728119 ipragliflozin [extracellular region] R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 134735 R-ALL-9709193 omarigliptin [extracellular region] R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 134735 R-ALL-9709193 omarigliptin [extracellular region] R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 134735 R-ALL-9709193 omarigliptin [extracellular region] R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 134735 R-ALL-9709193 omarigliptin [extracellular region] R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 134735 R-ALL-9709193 omarigliptin [extracellular region] R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 134735 R-ALL-9709193 omarigliptin [extracellular region] R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 134735 R-ALL-9709193 omarigliptin [extracellular region] R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 134735 R-ALL-9709193 omarigliptin [extracellular region] R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 134735 R-ALL-9709193 omarigliptin [extracellular region] R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 134735 R-ALL-9709193 omarigliptin [extracellular region] R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 134735 R-ALL-9709193 omarigliptin [extracellular region] R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 134735 R-ALL-9709193 omarigliptin [extracellular region] R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 134743 R-ALL-9732875 simeprevir [double membrane vesicle viral factory outer membrane] R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 134743 R-ALL-9732253 simeprevir [cytosol] R-HSA-9732822 https://reactome.org/PathwayBrowser/#/R-HSA-9732822 nsp3 binds to PLpro inhibitors TAS Homo sapiens 134991 R-ALL-9693485 frovatriptan [extracellular region] R-BTA-9693478 https://reactome.org/PathwayBrowser/#/R-BTA-9693478 HTR1A binds HTR1A agonists IEA Bos taurus 134991 R-ALL-9693485 frovatriptan [extracellular region] R-CEL-9693478 https://reactome.org/PathwayBrowser/#/R-CEL-9693478 HTR1A binds HTR1A agonists IEA Caenorhabditis elegans 134991 R-ALL-9693485 frovatriptan [extracellular region] R-CFA-9693478 https://reactome.org/PathwayBrowser/#/R-CFA-9693478 HTR1A binds HTR1A agonists IEA Canis familiaris 134991 R-ALL-9693485 frovatriptan [extracellular region] R-DME-9693478 https://reactome.org/PathwayBrowser/#/R-DME-9693478 HTR1A binds HTR1A agonists IEA Drosophila melanogaster 134991 R-ALL-9693485 frovatriptan [extracellular region] R-DRE-9693478 https://reactome.org/PathwayBrowser/#/R-DRE-9693478 HTR1A binds HTR1A agonists IEA Danio rerio 134991 R-ALL-9693485 frovatriptan [extracellular region] R-GGA-9693478 https://reactome.org/PathwayBrowser/#/R-GGA-9693478 HTR1A binds HTR1A agonists IEA Gallus gallus 134991 R-ALL-9693485 frovatriptan [extracellular region] R-HSA-9693478 https://reactome.org/PathwayBrowser/#/R-HSA-9693478 HTR1A binds HTR1A agonists TAS Homo sapiens 134991 R-ALL-9693485 frovatriptan [extracellular region] R-MMU-9693478 https://reactome.org/PathwayBrowser/#/R-MMU-9693478 HTR1A binds HTR1A agonists IEA Mus musculus 134991 R-ALL-9693485 frovatriptan [extracellular region] R-RNO-9693478 https://reactome.org/PathwayBrowser/#/R-RNO-9693478 HTR1A binds HTR1A agonists IEA Rattus norvegicus 134991 R-ALL-9693485 frovatriptan [extracellular region] R-XTR-9693478 https://reactome.org/PathwayBrowser/#/R-XTR-9693478 HTR1A binds HTR1A agonists IEA Xenopus tropicalis 135005 R-ALL-9714397 milnacipran [extracellular region] R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 135005 R-ALL-9714397 milnacipran [extracellular region] R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 135005 R-ALL-9714397 milnacipran [extracellular region] R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 135005 R-ALL-9714397 milnacipran [extracellular region] R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 135005 R-ALL-9714397 milnacipran [extracellular region] R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 135005 R-ALL-9714397 milnacipran [extracellular region] R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 135005 R-ALL-9714397 milnacipran [extracellular region] R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 135005 R-ALL-9714397 milnacipran [extracellular region] R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 135005 R-ALL-9714397 milnacipran [extracellular region] R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 135005 R-ALL-9714397 milnacipran [extracellular region] R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 135005 R-ALL-9714397 milnacipran [extracellular region] R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 135005 R-ALL-9714397 milnacipran [extracellular region] R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 135010 R-ALL-9629674 enoximone [cytosol] R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 135010 R-ALL-9629674 enoximone [cytosol] R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 135010 R-ALL-9629674 enoximone [cytosol] R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 135010 R-ALL-9629674 enoximone [cytosol] R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 135010 R-ALL-9629674 enoximone [cytosol] R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 135010 R-ALL-9629674 enoximone [cytosol] R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 135010 R-ALL-9629674 enoximone [cytosol] R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 135010 R-ALL-9629674 enoximone [cytosol] R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 135010 R-ALL-9629674 enoximone [cytosol] R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 135010 R-ALL-9629674 enoximone [cytosol] R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 135123 R-ALL-9611002 bupranolol [extracellular region] R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135123 R-ALL-9611002 bupranolol [extracellular region] R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 135123 R-ALL-9611002 bupranolol [extracellular region] R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 135123 R-ALL-9611002 bupranolol [extracellular region] R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 135123 R-ALL-9611002 bupranolol [extracellular region] R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 135123 R-ALL-9611002 bupranolol [extracellular region] R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 135123 R-ALL-9611002 bupranolol [extracellular region] R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 135123 R-ALL-9611002 bupranolol [extracellular region] R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135123 R-ALL-9611002 bupranolol [extracellular region] R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 135123 R-ALL-9611002 bupranolol [extracellular region] R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 135123 R-ALL-9611002 bupranolol [extracellular region] R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 135123 R-ALL-9611002 bupranolol [extracellular region] R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135123 R-ALL-9611002 bupranolol [extracellular region] R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 135123 R-ALL-9611002 bupranolol [extracellular region] R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 135123 R-ALL-9611002 bupranolol [extracellular region] R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135123 R-ALL-9611002 bupranolol [extracellular region] R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 135123 R-ALL-9611002 bupranolol [extracellular region] R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 135123 R-ALL-9611002 bupranolol [extracellular region] R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 135123 R-ALL-9611002 bupranolol [extracellular region] R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135123 R-ALL-9611002 bupranolol [extracellular region] R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 135123 R-ALL-9611002 bupranolol [extracellular region] R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 135123 R-ALL-9611002 bupranolol [extracellular region] R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 135123 R-ALL-9611002 bupranolol [extracellular region] R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135123 R-ALL-9611002 bupranolol [extracellular region] R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 135123 R-ALL-9611002 bupranolol [extracellular region] R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 135123 R-ALL-9611002 bupranolol [extracellular region] R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 135123 R-ALL-9611002 bupranolol [extracellular region] R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135123 R-ALL-9611002 bupranolol [extracellular region] R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 135123 R-ALL-9611002 bupranolol [extracellular region] R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 135123 R-ALL-9611002 bupranolol [extracellular region] R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 135123 R-ALL-9611002 bupranolol [extracellular region] R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135123 R-ALL-9611002 bupranolol [extracellular region] R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 135123 R-ALL-9611002 bupranolol [extracellular region] R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 135123 R-ALL-9611002 bupranolol [extracellular region] R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 135123 R-ALL-9611002 bupranolol [extracellular region] R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135123 R-ALL-9611002 bupranolol [extracellular region] R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 135123 R-ALL-9611002 bupranolol [extracellular region] R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 135156 R-ALL-9648941 ramosetron [cytosol] R-BTA-9648949 https://reactome.org/PathwayBrowser/#/R-BTA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Bos taurus 135156 R-ALL-9648941 ramosetron [cytosol] R-CEL-9648949 https://reactome.org/PathwayBrowser/#/R-CEL-9648949 HTR3A antagonists bind HTR3A pentamer IEA Caenorhabditis elegans 135156 R-ALL-9648941 ramosetron [cytosol] R-CFA-9648949 https://reactome.org/PathwayBrowser/#/R-CFA-9648949 HTR3A antagonists bind HTR3A pentamer IEA Canis familiaris 135156 R-ALL-9648941 ramosetron [cytosol] R-HSA-9648949 https://reactome.org/PathwayBrowser/#/R-HSA-9648949 HTR3A antagonists bind HTR3A pentamer TAS Homo sapiens 135156 R-ALL-9648941 ramosetron [cytosol] R-MMU-9648949 https://reactome.org/PathwayBrowser/#/R-MMU-9648949 HTR3A antagonists bind HTR3A pentamer IEA Mus musculus 135156 R-ALL-9648941 ramosetron [cytosol] R-RNO-9648949 https://reactome.org/PathwayBrowser/#/R-RNO-9648949 HTR3A antagonists bind HTR3A pentamer IEA Rattus norvegicus 135156 R-ALL-9648941 ramosetron [cytosol] R-SSC-9648949 https://reactome.org/PathwayBrowser/#/R-SSC-9648949 HTR3A antagonists bind HTR3A pentamer IEA Sus scrofa 135285 R-ALL-9709180 vildagliptin [extracellular region] R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 135285 R-ALL-9709180 vildagliptin [extracellular region] R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 135285 R-ALL-9709180 vildagliptin [extracellular region] R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 135285 R-ALL-9709180 vildagliptin [extracellular region] R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 135285 R-ALL-9709180 vildagliptin [extracellular region] R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 135285 R-ALL-9709180 vildagliptin [extracellular region] R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 135285 R-ALL-9709180 vildagliptin [extracellular region] R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 135285 R-ALL-9709180 vildagliptin [extracellular region] R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 135285 R-ALL-9709180 vildagliptin [extracellular region] R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 135285 R-ALL-9709180 vildagliptin [extracellular region] R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 135285 R-ALL-9709180 vildagliptin [extracellular region] R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 135285 R-ALL-9709180 vildagliptin [extracellular region] R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 135349 R-ALL-9652529 mitiglinide [extracellular region] R-BTA-9650858 https://reactome.org/PathwayBrowser/#/R-BTA-9650858 Meglitinides bind ABCC8 IEA Bos taurus 135349 R-ALL-9652529 mitiglinide [extracellular region] R-CFA-9650858 https://reactome.org/PathwayBrowser/#/R-CFA-9650858 Meglitinides bind ABCC8 IEA Canis familiaris 135349 R-ALL-9652529 mitiglinide [extracellular region] R-DME-9650858 https://reactome.org/PathwayBrowser/#/R-DME-9650858 Meglitinides bind ABCC8 IEA Drosophila melanogaster 135349 R-ALL-9652529 mitiglinide [extracellular region] R-GGA-9650858 https://reactome.org/PathwayBrowser/#/R-GGA-9650858 Meglitinides bind ABCC8 IEA Gallus gallus 135349 R-ALL-9652529 mitiglinide [extracellular region] R-HSA-9650858 https://reactome.org/PathwayBrowser/#/R-HSA-9650858 Meglitinides bind ABCC8 TAS Homo sapiens 135349 R-ALL-9652529 mitiglinide [extracellular region] R-MMU-9650858 https://reactome.org/PathwayBrowser/#/R-MMU-9650858 Meglitinides bind ABCC8 IEA Mus musculus 135349 R-ALL-9652529 mitiglinide [extracellular region] R-RNO-9650858 https://reactome.org/PathwayBrowser/#/R-RNO-9650858 Meglitinides bind ABCC8 IEA Rattus norvegicus 135349 R-ALL-9652529 mitiglinide [extracellular region] R-SSC-9650858 https://reactome.org/PathwayBrowser/#/R-SSC-9650858 Meglitinides bind ABCC8 IEA Sus scrofa 135349 R-ALL-9652529 mitiglinide [extracellular region] R-XTR-9650858 https://reactome.org/PathwayBrowser/#/R-XTR-9650858 Meglitinides bind ABCC8 IEA Xenopus tropicalis 135359 R-ALL-9611724 denopamine [extracellular region] R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135359 R-ALL-9611724 denopamine [extracellular region] R-BTA-9611721 https://reactome.org/PathwayBrowser/#/R-BTA-9611721 β1-agonists bind ADRB1 IEA Bos taurus 135359 R-ALL-9611724 denopamine [extracellular region] R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135359 R-ALL-9611724 denopamine [extracellular region] R-DME-9611721 https://reactome.org/PathwayBrowser/#/R-DME-9611721 β1-agonists bind ADRB1 IEA Drosophila melanogaster 135359 R-ALL-9611724 denopamine [extracellular region] R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135359 R-ALL-9611724 denopamine [extracellular region] R-DRE-9611721 https://reactome.org/PathwayBrowser/#/R-DRE-9611721 β1-agonists bind ADRB1 IEA Danio rerio 135359 R-ALL-9611724 denopamine [extracellular region] R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135359 R-ALL-9611724 denopamine [extracellular region] R-GGA-9611721 https://reactome.org/PathwayBrowser/#/R-GGA-9611721 β1-agonists bind ADRB1 IEA Gallus gallus 135359 R-ALL-9611724 denopamine [extracellular region] R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135359 R-ALL-9611724 denopamine [extracellular region] R-HSA-9611721 https://reactome.org/PathwayBrowser/#/R-HSA-9611721 β1-agonists bind ADRB1 TAS Homo sapiens 135359 R-ALL-9611724 denopamine [extracellular region] R-HSA-9695415 https://reactome.org/PathwayBrowser/#/R-HSA-9695415 glycosylated-ACE2 binds ACE2 inhibitors TAS Homo sapiens 135359 R-ALL-9611724 denopamine [extracellular region] R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135359 R-ALL-9611724 denopamine [extracellular region] R-MMU-9611721 https://reactome.org/PathwayBrowser/#/R-MMU-9611721 β1-agonists bind ADRB1 IEA Mus musculus 135359 R-ALL-9611724 denopamine [extracellular region] R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135359 R-ALL-9611724 denopamine [extracellular region] R-RNO-9611721 https://reactome.org/PathwayBrowser/#/R-RNO-9611721 β1-agonists bind ADRB1 IEA Rattus norvegicus 135359 R-ALL-9611724 denopamine [extracellular region] R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135359 R-ALL-9611724 denopamine [extracellular region] R-SSC-9611721 https://reactome.org/PathwayBrowser/#/R-SSC-9611721 β1-agonists bind ADRB1 IEA Sus scrofa 135359 R-ALL-9611724 denopamine [extracellular region] R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135359 R-ALL-9611724 denopamine [extracellular region] R-XTR-9611721 https://reactome.org/PathwayBrowser/#/R-XTR-9611721 β1-agonists bind ADRB1 IEA Xenopus tropicalis 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 135361 R-ALL-9704148 N-methyl scopolamine [extracellular region] R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 135377 R-ALL-9618315 cicloprolol [extracellular region] R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-BTA-9609310 https://reactome.org/PathwayBrowser/#/R-BTA-9609310 β-blockers bind ADRB1,2,3 IEA Bos taurus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-CFA-9609310 https://reactome.org/PathwayBrowser/#/R-CFA-9609310 β-blockers bind ADRB1,2,3 IEA Canis familiaris 135377 R-ALL-9618315 cicloprolol [extracellular region] R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 135377 R-ALL-9618315 cicloprolol [extracellular region] R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DME-9609310 https://reactome.org/PathwayBrowser/#/R-DME-9609310 β-blockers bind ADRB1,2,3 IEA Drosophila melanogaster 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DRE-9609310 https://reactome.org/PathwayBrowser/#/R-DRE-9609310 β-blockers bind ADRB1,2,3 IEA Danio rerio 135377 R-ALL-9618315 cicloprolol [extracellular region] R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 135377 R-ALL-9618315 cicloprolol [extracellular region] R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-GGA-9609310 https://reactome.org/PathwayBrowser/#/R-GGA-9609310 β-blockers bind ADRB1,2,3 IEA Gallus gallus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 135377 R-ALL-9618315 cicloprolol [extracellular region] R-HSA-9609310 https://reactome.org/PathwayBrowser/#/R-HSA-9609310 β-blockers bind ADRB1,2,3 TAS Homo sapiens 135377 R-ALL-9618315 cicloprolol [extracellular region] R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 135377 R-ALL-9618315 cicloprolol [extracellular region] R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 135377 R-ALL-9618315 cicloprolol [extracellular region] R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-MMU-9609310 https://reactome.org/PathwayBrowser/#/R-MMU-9609310 β-blockers bind ADRB1,2,3 IEA Mus musculus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-RNO-9609310 https://reactome.org/PathwayBrowser/#/R-RNO-9609310 β-blockers bind ADRB1,2,3 IEA Rattus norvegicus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 135377 R-ALL-9618315 cicloprolol [extracellular region] R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 135377 R-ALL-9618315 cicloprolol [extracellular region] R-SSC-9609310 https://reactome.org/PathwayBrowser/#/R-SSC-9609310 β-blockers bind ADRB1,2,3 IEA Sus scrofa 135377 R-ALL-9618315 cicloprolol [extracellular region] R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 135377 R-ALL-9618315 cicloprolol [extracellular region] R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 135377 R-ALL-9618315 cicloprolol [extracellular region] R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 135377 R-ALL-9618315 cicloprolol [extracellular region] R-XTR-9609310 https://reactome.org/PathwayBrowser/#/R-XTR-9609310 β-blockers bind ADRB1,2,3 IEA Xenopus tropicalis 135377 R-ALL-9618315 cicloprolol [extracellular region] R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 135466 R-ALL-9649965 nafamostat [extracellular region] R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 135466 R-ALL-9649965 nafamostat [extracellular region] R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 135466 R-ALL-9649965 nafamostat [extracellular region] R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 135466 R-ALL-9649965 nafamostat [extracellular region] R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 135466 R-ALL-9649965 nafamostat [extracellular region] R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 135466 R-ALL-9649965 nafamostat [extracellular region] R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 135466 R-ALL-9649965 nafamostat [extracellular region] R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 135466 R-ALL-9649965 nafamostat [extracellular region] R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 135466 R-ALL-9649965 nafamostat [extracellular region] R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 135466 R-ALL-9649965 nafamostat [extracellular region] R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 135466 R-ALL-9649965 nafamostat [extracellular region] R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 135466 R-ALL-9649965 nafamostat [extracellular region] R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 135466 R-ALL-9649965 nafamostat [extracellular region] R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 135466 R-ALL-9649965 nafamostat [extracellular region] R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 135530 R-ALL-9704140 solifenacin [extracellular region] R-BTA-9704151 https://reactome.org/PathwayBrowser/#/R-BTA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Bos taurus 135530 R-ALL-9704140 solifenacin [extracellular region] R-CEL-9704151 https://reactome.org/PathwayBrowser/#/R-CEL-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Caenorhabditis elegans 135530 R-ALL-9704140 solifenacin [extracellular region] R-CFA-9704151 https://reactome.org/PathwayBrowser/#/R-CFA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Canis familiaris 135530 R-ALL-9704140 solifenacin [extracellular region] R-DME-9704151 https://reactome.org/PathwayBrowser/#/R-DME-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Drosophila melanogaster 135530 R-ALL-9704140 solifenacin [extracellular region] R-DRE-9704151 https://reactome.org/PathwayBrowser/#/R-DRE-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Danio rerio 135530 R-ALL-9704140 solifenacin [extracellular region] R-GGA-9704151 https://reactome.org/PathwayBrowser/#/R-GGA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Gallus gallus 135530 R-ALL-9704140 solifenacin [extracellular region] R-HSA-9704151 https://reactome.org/PathwayBrowser/#/R-HSA-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists TAS Homo sapiens 135530 R-ALL-9704140 solifenacin [extracellular region] R-MMU-9704151 https://reactome.org/PathwayBrowser/#/R-MMU-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Mus musculus 135530 R-ALL-9704140 solifenacin [extracellular region] R-RNO-9704151 https://reactome.org/PathwayBrowser/#/R-RNO-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Rattus norvegicus 135530 R-ALL-9704140 solifenacin [extracellular region] R-SSC-9704151 https://reactome.org/PathwayBrowser/#/R-SSC-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Sus scrofa 135530 R-ALL-9704140 solifenacin [extracellular region] R-XTR-9704151 https://reactome.org/PathwayBrowser/#/R-XTR-9704151 CHRM1,3,5 bind CHRM1,3,5 antagonists IEA Xenopus tropicalis 135544 R-ALL-9727227 ilaprazole [extracellular region] R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 135544 R-ALL-9727227 ilaprazole [extracellular region] R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 135544 R-ALL-9727227 ilaprazole [extracellular region] R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 135544 R-ALL-9727227 ilaprazole [extracellular region] R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 135544 R-ALL-9727227 ilaprazole [extracellular region] R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 135544 R-ALL-9727227 ilaprazole [extracellular region] R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 135544 R-ALL-9727227 ilaprazole [extracellular region] R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 135566 R-ALL-9717024 rimexolone [cytosol] R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 135566 R-ALL-9717024 rimexolone [cytosol] R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 135566 R-ALL-9717024 rimexolone [cytosol] R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 135566 R-ALL-9717024 rimexolone [cytosol] R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 135566 R-ALL-9717024 rimexolone [cytosol] R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 135566 R-ALL-9717024 rimexolone [cytosol] R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 135566 R-ALL-9717024 rimexolone [cytosol] R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 135566 R-ALL-9717024 rimexolone [cytosol] R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 135566 R-ALL-9717024 rimexolone [cytosol] R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 135566 R-ALL-9717024 rimexolone [cytosol] R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 135566 R-ALL-9717024 rimexolone [cytosol] R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 135566 R-ALL-9717024 rimexolone [cytosol] R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 135566 R-ALL-9717024 rimexolone [cytosol] R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 135566 R-ALL-9717024 rimexolone [cytosol] R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 135566 R-ALL-9717024 rimexolone [cytosol] R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 135566 R-ALL-9717024 rimexolone [cytosol] R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 135566 R-ALL-9717024 rimexolone [cytosol] R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 135566 R-ALL-9717024 rimexolone [cytosol] R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 135566 R-ALL-9717024 rimexolone [cytosol] R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 135566 R-ALL-9717024 rimexolone [cytosol] R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 135566 R-ALL-9717024 rimexolone [cytosol] R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 135566 R-ALL-9717024 rimexolone [cytosol] R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 135574 R-ALL-9696496 nabilone [extracellular region] R-BTA-9696323 https://reactome.org/PathwayBrowser/#/R-BTA-9696323 CNRs bind CNR agonists IEA Bos taurus 135574 R-ALL-9696496 nabilone [extracellular region] R-CFA-9696323 https://reactome.org/PathwayBrowser/#/R-CFA-9696323 CNRs bind CNR agonists IEA Canis familiaris 135574 R-ALL-9696496 nabilone [extracellular region] R-DRE-9696323 https://reactome.org/PathwayBrowser/#/R-DRE-9696323 CNRs bind CNR agonists IEA Danio rerio 135574 R-ALL-9696496 nabilone [extracellular region] R-GGA-9696323 https://reactome.org/PathwayBrowser/#/R-GGA-9696323 CNRs bind CNR agonists IEA Gallus gallus 135574 R-ALL-9696496 nabilone [extracellular region] R-HSA-9696323 https://reactome.org/PathwayBrowser/#/R-HSA-9696323 CNRs bind CNR agonists TAS Homo sapiens 135574 R-ALL-9696496 nabilone [extracellular region] R-MMU-9696323 https://reactome.org/PathwayBrowser/#/R-MMU-9696323 CNRs bind CNR agonists IEA Mus musculus 135574 R-ALL-9696496 nabilone [extracellular region] R-RNO-9696323 https://reactome.org/PathwayBrowser/#/R-RNO-9696323 CNRs bind CNR agonists IEA Rattus norvegicus 135574 R-ALL-9696496 nabilone [extracellular region] R-SSC-9696323 https://reactome.org/PathwayBrowser/#/R-SSC-9696323 CNRs bind CNR agonists IEA Sus scrofa 135574 R-ALL-9696496 nabilone [extracellular region] R-XTR-9696323 https://reactome.org/PathwayBrowser/#/R-XTR-9696323 CNRs bind CNR agonists IEA Xenopus tropicalis 135632 R-ALL-9678726 camostat [extracellular region] R-HSA-9681514 https://reactome.org/PathwayBrowser/#/R-HSA-9681514 TMPRSS2 binds TMPRSS2 inhibitors TAS Homo sapiens 135632 R-ALL-9678726 camostat [extracellular region] R-HSA-9686731 https://reactome.org/PathwayBrowser/#/R-HSA-9686731 TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 135632 R-ALL-9678726 camostat [extracellular region] R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 135652 R-ALL-9700680 flunarizine [extracellular region] R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 135652 R-ALL-9700680 flunarizine [extracellular region] R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 135652 R-ALL-9700680 flunarizine [extracellular region] R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 135652 R-ALL-9700680 flunarizine [extracellular region] R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 135652 R-ALL-9700680 flunarizine [extracellular region] R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 135654 R-ALL-9619019 imidapril [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 135673 R-ALL-9692522 rupatadine [extracellular region] R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 135673 R-ALL-9692522 rupatadine [extracellular region] R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 135673 R-ALL-9692522 rupatadine [extracellular region] R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 135673 R-ALL-9692522 rupatadine [extracellular region] R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 135673 R-ALL-9692522 rupatadine [extracellular region] R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 135673 R-ALL-9692522 rupatadine [extracellular region] R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 135673 R-ALL-9692522 rupatadine [extracellular region] R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 135673 R-ALL-9692522 rupatadine [extracellular region] R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 135694 R-ALL-9703962 mozavaptan [extracellular region] R-BTA-9667569 https://reactome.org/PathwayBrowser/#/R-BTA-9667569 AVPR1A,2 bind AVPR antagonists IEA Bos taurus 135694 R-ALL-9703962 mozavaptan [extracellular region] R-CFA-9667569 https://reactome.org/PathwayBrowser/#/R-CFA-9667569 AVPR1A,2 bind AVPR antagonists IEA Canis familiaris 135694 R-ALL-9703962 mozavaptan [extracellular region] R-DRE-9667569 https://reactome.org/PathwayBrowser/#/R-DRE-9667569 AVPR1A,2 bind AVPR antagonists IEA Danio rerio 135694 R-ALL-9703962 mozavaptan [extracellular region] R-GGA-9667569 https://reactome.org/PathwayBrowser/#/R-GGA-9667569 AVPR1A,2 bind AVPR antagonists IEA Gallus gallus 135694 R-ALL-9703962 mozavaptan [extracellular region] R-HSA-9667569 https://reactome.org/PathwayBrowser/#/R-HSA-9667569 AVPR1A,2 bind AVPR antagonists TAS Homo sapiens 135694 R-ALL-9703962 mozavaptan [extracellular region] R-MMU-9667569 https://reactome.org/PathwayBrowser/#/R-MMU-9667569 AVPR1A,2 bind AVPR antagonists IEA Mus musculus 135694 R-ALL-9703962 mozavaptan [extracellular region] R-RNO-9667569 https://reactome.org/PathwayBrowser/#/R-RNO-9667569 AVPR1A,2 bind AVPR antagonists IEA Rattus norvegicus 135694 R-ALL-9703962 mozavaptan [extracellular region] R-SSC-9667569 https://reactome.org/PathwayBrowser/#/R-SSC-9667569 AVPR1A,2 bind AVPR antagonists IEA Sus scrofa 135694 R-ALL-9703962 mozavaptan [extracellular region] R-XTR-9667569 https://reactome.org/PathwayBrowser/#/R-XTR-9667569 AVPR1A,2 bind AVPR antagonists IEA Xenopus tropicalis 135720 R-ALL-9717033 deflazacort [cytosol] R-BTA-9678925 https://reactome.org/PathwayBrowser/#/R-BTA-9678925 NR3C1 binds NR3C1 agonists IEA Bos taurus 135720 R-ALL-9717033 deflazacort [cytosol] R-BTA-9690534 https://reactome.org/PathwayBrowser/#/R-BTA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Bos taurus 135720 R-ALL-9717033 deflazacort [cytosol] R-CFA-9678925 https://reactome.org/PathwayBrowser/#/R-CFA-9678925 NR3C1 binds NR3C1 agonists IEA Canis familiaris 135720 R-ALL-9717033 deflazacort [cytosol] R-CFA-9690534 https://reactome.org/PathwayBrowser/#/R-CFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Canis familiaris 135720 R-ALL-9717033 deflazacort [cytosol] R-DME-9678925 https://reactome.org/PathwayBrowser/#/R-DME-9678925 NR3C1 binds NR3C1 agonists IEA Drosophila melanogaster 135720 R-ALL-9717033 deflazacort [cytosol] R-DME-9690534 https://reactome.org/PathwayBrowser/#/R-DME-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Drosophila melanogaster 135720 R-ALL-9717033 deflazacort [cytosol] R-DRE-9678925 https://reactome.org/PathwayBrowser/#/R-DRE-9678925 NR3C1 binds NR3C1 agonists IEA Danio rerio 135720 R-ALL-9717033 deflazacort [cytosol] R-DRE-9690534 https://reactome.org/PathwayBrowser/#/R-DRE-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Danio rerio 135720 R-ALL-9717033 deflazacort [cytosol] R-GGA-9678925 https://reactome.org/PathwayBrowser/#/R-GGA-9678925 NR3C1 binds NR3C1 agonists IEA Gallus gallus 135720 R-ALL-9717033 deflazacort [cytosol] R-GGA-9690534 https://reactome.org/PathwayBrowser/#/R-GGA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Gallus gallus 135720 R-ALL-9717033 deflazacort [cytosol] R-HSA-9678925 https://reactome.org/PathwayBrowser/#/R-HSA-9678925 NR3C1 binds NR3C1 agonists TAS Homo sapiens 135720 R-ALL-9717033 deflazacort [cytosol] R-HSA-9690534 https://reactome.org/PathwayBrowser/#/R-HSA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) TAS Homo sapiens 135720 R-ALL-9717033 deflazacort [cytosol] R-MMU-9678925 https://reactome.org/PathwayBrowser/#/R-MMU-9678925 NR3C1 binds NR3C1 agonists IEA Mus musculus 135720 R-ALL-9717033 deflazacort [cytosol] R-MMU-9690534 https://reactome.org/PathwayBrowser/#/R-MMU-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Mus musculus 135720 R-ALL-9717033 deflazacort [cytosol] R-PFA-9678925 https://reactome.org/PathwayBrowser/#/R-PFA-9678925 NR3C1 binds NR3C1 agonists IEA Plasmodium falciparum 135720 R-ALL-9717033 deflazacort [cytosol] R-PFA-9690534 https://reactome.org/PathwayBrowser/#/R-PFA-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Plasmodium falciparum 135720 R-ALL-9717033 deflazacort [cytosol] R-RNO-9678925 https://reactome.org/PathwayBrowser/#/R-RNO-9678925 NR3C1 binds NR3C1 agonists IEA Rattus norvegicus 135720 R-ALL-9717033 deflazacort [cytosol] R-RNO-9690534 https://reactome.org/PathwayBrowser/#/R-RNO-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Rattus norvegicus 135720 R-ALL-9717033 deflazacort [cytosol] R-SSC-9678925 https://reactome.org/PathwayBrowser/#/R-SSC-9678925 NR3C1 binds NR3C1 agonists IEA Sus scrofa 135720 R-ALL-9717033 deflazacort [cytosol] R-SSC-9690534 https://reactome.org/PathwayBrowser/#/R-SSC-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Sus scrofa 135720 R-ALL-9717033 deflazacort [cytosol] R-XTR-9678925 https://reactome.org/PathwayBrowser/#/R-XTR-9678925 NR3C1 binds NR3C1 agonists IEA Xenopus tropicalis 135720 R-ALL-9717033 deflazacort [cytosol] R-XTR-9690534 https://reactome.org/PathwayBrowser/#/R-XTR-9690534 NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) IEA Xenopus tropicalis 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-BTA-9731931 https://reactome.org/PathwayBrowser/#/R-BTA-9731931 EDNRA binds selective ERAs IEA Bos taurus 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-CFA-9731931 https://reactome.org/PathwayBrowser/#/R-CFA-9731931 EDNRA binds selective ERAs IEA Canis familiaris 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-DRE-9731931 https://reactome.org/PathwayBrowser/#/R-DRE-9731931 EDNRA binds selective ERAs IEA Danio rerio 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-GGA-9731931 https://reactome.org/PathwayBrowser/#/R-GGA-9731931 EDNRA binds selective ERAs IEA Gallus gallus 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-HSA-9731931 https://reactome.org/PathwayBrowser/#/R-HSA-9731931 EDNRA binds selective ERAs TAS Homo sapiens 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-MMU-9731931 https://reactome.org/PathwayBrowser/#/R-MMU-9731931 EDNRA binds selective ERAs IEA Mus musculus 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-RNO-9731931 https://reactome.org/PathwayBrowser/#/R-RNO-9731931 EDNRA binds selective ERAs IEA Rattus norvegicus 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-SSC-9731931 https://reactome.org/PathwayBrowser/#/R-SSC-9731931 EDNRA binds selective ERAs IEA Sus scrofa 135736 R-ALL-9731345 sitaxsentan [extracellular region] R-XTR-9731931 https://reactome.org/PathwayBrowser/#/R-XTR-9731931 EDNRA binds selective ERAs IEA Xenopus tropicalis 135738 R-ALL-9614105 clevidipine [extracellular region] R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 135738 R-ALL-9614105 clevidipine [extracellular region] R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 135738 R-ALL-9614105 clevidipine [extracellular region] R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 135738 R-ALL-9614105 clevidipine [extracellular region] R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 135738 R-ALL-9614105 clevidipine [extracellular region] R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 135738 R-ALL-9614105 clevidipine [extracellular region] R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 135738 R-ALL-9614105 clevidipine [extracellular region] R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 135738 R-ALL-9614105 clevidipine [extracellular region] R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 135738 R-ALL-9614105 clevidipine [extracellular region] R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 135738 R-ALL-9614105 clevidipine [extracellular region] R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-BTA-9705926 https://reactome.org/PathwayBrowser/#/R-BTA-9705926 AR binds AR agonists IEA Bos taurus 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-CFA-9705926 https://reactome.org/PathwayBrowser/#/R-CFA-9705926 AR binds AR agonists IEA Canis familiaris 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-DME-9705926 https://reactome.org/PathwayBrowser/#/R-DME-9705926 AR binds AR agonists IEA Drosophila melanogaster 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-DRE-9705926 https://reactome.org/PathwayBrowser/#/R-DRE-9705926 AR binds AR agonists IEA Danio rerio 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-GGA-9705926 https://reactome.org/PathwayBrowser/#/R-GGA-9705926 AR binds AR agonists IEA Gallus gallus 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-HSA-9705926 https://reactome.org/PathwayBrowser/#/R-HSA-9705926 AR binds AR agonists TAS Homo sapiens 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-MMU-9705926 https://reactome.org/PathwayBrowser/#/R-MMU-9705926 AR binds AR agonists IEA Mus musculus 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-PFA-9705926 https://reactome.org/PathwayBrowser/#/R-PFA-9705926 AR binds AR agonists IEA Plasmodium falciparum 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-RNO-9705926 https://reactome.org/PathwayBrowser/#/R-RNO-9705926 AR binds AR agonists IEA Rattus norvegicus 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-SSC-9705926 https://reactome.org/PathwayBrowser/#/R-SSC-9705926 AR binds AR agonists IEA Sus scrofa 135741 R-ALL-9705885 testosterone undecanoate [cytosol] R-XTR-9705926 https://reactome.org/PathwayBrowser/#/R-XTR-9705926 AR binds AR agonists IEA Xenopus tropicalis 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 135756 R-ALL-9619016 spirapril [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 135847 R-ALL-9660999 biricodar [cytosol] R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 135847 R-ALL-9660999 biricodar [cytosol] R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 135847 R-ALL-9660999 biricodar [cytosol] R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 135847 R-ALL-9660999 biricodar [cytosol] R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 135847 R-ALL-9660999 biricodar [cytosol] R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 135847 R-ALL-9660999 biricodar [cytosol] R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 135847 R-ALL-9660999 biricodar [cytosol] R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 135847 R-ALL-9660999 biricodar [cytosol] R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 135847 R-ALL-9660999 biricodar [cytosol] R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 135847 R-ALL-9660999 biricodar [cytosol] R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 135849 R-ALL-9700699 manidipine [extracellular region] R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 135849 R-ALL-9700699 manidipine [extracellular region] R-BTA-9700701 https://reactome.org/PathwayBrowser/#/R-BTA-9700701 T-type VDCC bind T-type VDCC blockers IEA Bos taurus 135849 R-ALL-9700699 manidipine [extracellular region] R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 135849 R-ALL-9700699 manidipine [extracellular region] R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 135849 R-ALL-9700699 manidipine [extracellular region] R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 135849 R-ALL-9700699 manidipine [extracellular region] R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 135849 R-ALL-9700699 manidipine [extracellular region] R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 135849 R-ALL-9700699 manidipine [extracellular region] R-HSA-9700701 https://reactome.org/PathwayBrowser/#/R-HSA-9700701 T-type VDCC bind T-type VDCC blockers TAS Homo sapiens 135849 R-ALL-9700699 manidipine [extracellular region] R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 135849 R-ALL-9700699 manidipine [extracellular region] R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 135849 R-ALL-9700699 manidipine [extracellular region] R-SCE-9700701 https://reactome.org/PathwayBrowser/#/R-SCE-9700701 T-type VDCC bind T-type VDCC blockers IEA Saccharomyces cerevisiae 135849 R-ALL-9700699 manidipine [extracellular region] R-SPO-9700701 https://reactome.org/PathwayBrowser/#/R-SPO-9700701 T-type VDCC bind T-type VDCC blockers IEA Schizosaccharomyces pombe 135849 R-ALL-9700699 manidipine [extracellular region] R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 135849 R-ALL-9700699 manidipine [extracellular region] R-SSC-9700701 https://reactome.org/PathwayBrowser/#/R-SSC-9700701 T-type VDCC bind T-type VDCC blockers IEA Sus scrofa 135849 R-ALL-9700699 manidipine [extracellular region] R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 135899 R-ALL-9667607 atosiban [extracellular region] R-BTA-9667619 https://reactome.org/PathwayBrowser/#/R-BTA-9667619 AVPR1A,B,2 bind atosiban IEA Bos taurus 135899 R-ALL-9667607 atosiban [extracellular region] R-CFA-9667619 https://reactome.org/PathwayBrowser/#/R-CFA-9667619 AVPR1A,B,2 bind atosiban IEA Canis familiaris 135899 R-ALL-9667607 atosiban [extracellular region] R-DRE-9667619 https://reactome.org/PathwayBrowser/#/R-DRE-9667619 AVPR1A,B,2 bind atosiban IEA Danio rerio 135899 R-ALL-9667607 atosiban [extracellular region] R-GGA-9667619 https://reactome.org/PathwayBrowser/#/R-GGA-9667619 AVPR1A,B,2 bind atosiban IEA Gallus gallus 135899 R-ALL-9667607 atosiban [extracellular region] R-HSA-9667619 https://reactome.org/PathwayBrowser/#/R-HSA-9667619 AVPR1A,B,2 bind atosiban TAS Homo sapiens 135899 R-ALL-9667607 atosiban [extracellular region] R-MMU-9667619 https://reactome.org/PathwayBrowser/#/R-MMU-9667619 AVPR1A,B,2 bind atosiban IEA Mus musculus 135899 R-ALL-9667607 atosiban [extracellular region] R-RNO-9667619 https://reactome.org/PathwayBrowser/#/R-RNO-9667619 AVPR1A,B,2 bind atosiban IEA Rattus norvegicus 135899 R-ALL-9667607 atosiban [extracellular region] R-SSC-9667619 https://reactome.org/PathwayBrowser/#/R-SSC-9667619 AVPR1A,B,2 bind atosiban IEA Sus scrofa 135899 R-ALL-9667607 atosiban [extracellular region] R-XTR-9667619 https://reactome.org/PathwayBrowser/#/R-XTR-9667619 AVPR1A,B,2 bind atosiban IEA Xenopus tropicalis 135907 R-ALL-9718359 buserelin [extracellular region] R-BTA-9718360 https://reactome.org/PathwayBrowser/#/R-BTA-9718360 GNRHR binds GNRHR peptide agonists IEA Bos taurus 135907 R-ALL-9718359 buserelin [extracellular region] R-CEL-9718360 https://reactome.org/PathwayBrowser/#/R-CEL-9718360 GNRHR binds GNRHR peptide agonists IEA Caenorhabditis elegans 135907 R-ALL-9718359 buserelin [extracellular region] R-CFA-9718360 https://reactome.org/PathwayBrowser/#/R-CFA-9718360 GNRHR binds GNRHR peptide agonists IEA Canis familiaris 135907 R-ALL-9718359 buserelin [extracellular region] R-DME-9718360 https://reactome.org/PathwayBrowser/#/R-DME-9718360 GNRHR binds GNRHR peptide agonists IEA Drosophila melanogaster 135907 R-ALL-9718359 buserelin [extracellular region] R-DRE-9718360 https://reactome.org/PathwayBrowser/#/R-DRE-9718360 GNRHR binds GNRHR peptide agonists IEA Danio rerio 135907 R-ALL-9718359 buserelin [extracellular region] R-GGA-9718360 https://reactome.org/PathwayBrowser/#/R-GGA-9718360 GNRHR binds GNRHR peptide agonists IEA Gallus gallus 135907 R-ALL-9718359 buserelin [extracellular region] R-HSA-9718360 https://reactome.org/PathwayBrowser/#/R-HSA-9718360 GNRHR binds GNRHR peptide agonists TAS Homo sapiens 135907 R-ALL-9718359 buserelin [extracellular region] R-MMU-9718360 https://reactome.org/PathwayBrowser/#/R-MMU-9718360 GNRHR binds GNRHR peptide agonists IEA Mus musculus 135907 R-ALL-9718359 buserelin [extracellular region] R-RNO-9718360 https://reactome.org/PathwayBrowser/#/R-RNO-9718360 GNRHR binds GNRHR peptide agonists IEA Rattus norvegicus 135907 R-ALL-9718359 buserelin [extracellular region] R-SSC-9718360 https://reactome.org/PathwayBrowser/#/R-SSC-9718360 GNRHR binds GNRHR peptide agonists IEA Sus scrofa 135907 R-ALL-9718359 buserelin [extracellular region] R-XTR-9718360 https://reactome.org/PathwayBrowser/#/R-XTR-9718360 GNRHR binds GNRHR peptide agonists IEA Xenopus tropicalis 135926 R-ALL-9708114 udenafil [cytosol] R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 135926 R-ALL-9708114 udenafil [cytosol] R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 135926 R-ALL-9708114 udenafil [cytosol] R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 135926 R-ALL-9708114 udenafil [cytosol] R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 135926 R-ALL-9708114 udenafil [cytosol] R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 135926 R-ALL-9708114 udenafil [cytosol] R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 135926 R-ALL-9708114 udenafil [cytosol] R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 135926 R-ALL-9708114 udenafil [cytosol] R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 135926 R-ALL-9708114 udenafil [cytosol] R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-BTA-9727188 https://reactome.org/PathwayBrowser/#/R-BTA-9727188 ATP4A:ATP4B binds PPIs IEA Bos taurus 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-CFA-9727188 https://reactome.org/PathwayBrowser/#/R-CFA-9727188 ATP4A:ATP4B binds PPIs IEA Canis familiaris 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-HSA-9727188 https://reactome.org/PathwayBrowser/#/R-HSA-9727188 ATP4A:ATP4B binds PPIs TAS Homo sapiens 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-MMU-9727188 https://reactome.org/PathwayBrowser/#/R-MMU-9727188 ATP4A:ATP4B binds PPIs IEA Mus musculus 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-RNO-9727188 https://reactome.org/PathwayBrowser/#/R-RNO-9727188 ATP4A:ATP4B binds PPIs IEA Rattus norvegicus 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-SSC-9727188 https://reactome.org/PathwayBrowser/#/R-SSC-9727188 ATP4A:ATP4B binds PPIs IEA Sus scrofa 135931 R-ALL-9727234 dexlansoprazole [extracellular region] R-XTR-9727188 https://reactome.org/PathwayBrowser/#/R-XTR-9727188 ATP4A:ATP4B binds PPIs IEA Xenopus tropicalis 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-BTA-9716913 https://reactome.org/PathwayBrowser/#/R-BTA-9716913 ESR1 binds ESR1 antagonists IEA Bos taurus 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-DME-9716913 https://reactome.org/PathwayBrowser/#/R-DME-9716913 ESR1 binds ESR1 antagonists IEA Drosophila melanogaster 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-DRE-9716913 https://reactome.org/PathwayBrowser/#/R-DRE-9716913 ESR1 binds ESR1 antagonists IEA Danio rerio 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-GGA-9716913 https://reactome.org/PathwayBrowser/#/R-GGA-9716913 ESR1 binds ESR1 antagonists IEA Gallus gallus 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-HSA-9716913 https://reactome.org/PathwayBrowser/#/R-HSA-9716913 ESR1 binds ESR1 antagonists TAS Homo sapiens 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-MMU-9716913 https://reactome.org/PathwayBrowser/#/R-MMU-9716913 ESR1 binds ESR1 antagonists IEA Mus musculus 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-RNO-9716913 https://reactome.org/PathwayBrowser/#/R-RNO-9716913 ESR1 binds ESR1 antagonists IEA Rattus norvegicus 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-SSC-9716913 https://reactome.org/PathwayBrowser/#/R-SSC-9716913 ESR1 binds ESR1 antagonists IEA Sus scrofa 135947 R-ALL-9716891 bazedoxifene [nucleoplasm] R-XTR-9716913 https://reactome.org/PathwayBrowser/#/R-XTR-9716913 ESR1 binds ESR1 antagonists IEA Xenopus tropicalis 135949 R-ALL-9731344 ambrisentan [extracellular region] R-BTA-9731931 https://reactome.org/PathwayBrowser/#/R-BTA-9731931 EDNRA binds selective ERAs IEA Bos taurus 135949 R-ALL-9731344 ambrisentan [extracellular region] R-CFA-9731931 https://reactome.org/PathwayBrowser/#/R-CFA-9731931 EDNRA binds selective ERAs IEA Canis familiaris 135949 R-ALL-9731344 ambrisentan [extracellular region] R-DRE-9731931 https://reactome.org/PathwayBrowser/#/R-DRE-9731931 EDNRA binds selective ERAs IEA Danio rerio 135949 R-ALL-9731344 ambrisentan [extracellular region] R-GGA-9731931 https://reactome.org/PathwayBrowser/#/R-GGA-9731931 EDNRA binds selective ERAs IEA Gallus gallus 135949 R-ALL-9731344 ambrisentan [extracellular region] R-HSA-9731931 https://reactome.org/PathwayBrowser/#/R-HSA-9731931 EDNRA binds selective ERAs TAS Homo sapiens 135949 R-ALL-9731344 ambrisentan [extracellular region] R-MMU-9731931 https://reactome.org/PathwayBrowser/#/R-MMU-9731931 EDNRA binds selective ERAs IEA Mus musculus 135949 R-ALL-9731344 ambrisentan [extracellular region] R-RNO-9731931 https://reactome.org/PathwayBrowser/#/R-RNO-9731931 EDNRA binds selective ERAs IEA Rattus norvegicus 135949 R-ALL-9731344 ambrisentan [extracellular region] R-SSC-9731931 https://reactome.org/PathwayBrowser/#/R-SSC-9731931 EDNRA binds selective ERAs IEA Sus scrofa 135949 R-ALL-9731344 ambrisentan [extracellular region] R-XTR-9731931 https://reactome.org/PathwayBrowser/#/R-XTR-9731931 EDNRA binds selective ERAs IEA Xenopus tropicalis 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-BTA-9701064 https://reactome.org/PathwayBrowser/#/R-BTA-9701064 TRPV1 binds TRPV1 agonists IEA Bos taurus 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-CEL-9701064 https://reactome.org/PathwayBrowser/#/R-CEL-9701064 TRPV1 binds TRPV1 agonists IEA Caenorhabditis elegans 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-CFA-9701064 https://reactome.org/PathwayBrowser/#/R-CFA-9701064 TRPV1 binds TRPV1 agonists IEA Canis familiaris 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-DME-9701064 https://reactome.org/PathwayBrowser/#/R-DME-9701064 TRPV1 binds TRPV1 agonists IEA Drosophila melanogaster 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-DRE-9701064 https://reactome.org/PathwayBrowser/#/R-DRE-9701064 TRPV1 binds TRPV1 agonists IEA Danio rerio 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-GGA-9701064 https://reactome.org/PathwayBrowser/#/R-GGA-9701064 TRPV1 binds TRPV1 agonists IEA Gallus gallus 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-HSA-9701064 https://reactome.org/PathwayBrowser/#/R-HSA-9701064 TRPV1 binds TRPV1 agonists TAS Homo sapiens 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-MMU-9701064 https://reactome.org/PathwayBrowser/#/R-MMU-9701064 TRPV1 binds TRPV1 agonists IEA Mus musculus 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-RNO-9701064 https://reactome.org/PathwayBrowser/#/R-RNO-9701064 TRPV1 binds TRPV1 agonists IEA Rattus norvegicus 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-SCE-9701064 https://reactome.org/PathwayBrowser/#/R-SCE-9701064 TRPV1 binds TRPV1 agonists IEA Saccharomyces cerevisiae 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-SSC-9701064 https://reactome.org/PathwayBrowser/#/R-SSC-9701064 TRPV1 binds TRPV1 agonists IEA Sus scrofa 135952 R-ALL-9701121 zucapsaicin [extracellular region] R-XTR-9701064 https://reactome.org/PathwayBrowser/#/R-XTR-9701064 TRPV1 binds TRPV1 agonists IEA Xenopus tropicalis 135954 R-ALL-9692684 bilastine [extracellular region] R-CEL-9692539 https://reactome.org/PathwayBrowser/#/R-CEL-9692539 HRH1 binds HRH1 inverse agonists IEA Caenorhabditis elegans 135954 R-ALL-9692684 bilastine [extracellular region] R-CFA-9692539 https://reactome.org/PathwayBrowser/#/R-CFA-9692539 HRH1 binds HRH1 inverse agonists IEA Canis familiaris 135954 R-ALL-9692684 bilastine [extracellular region] R-GGA-9692539 https://reactome.org/PathwayBrowser/#/R-GGA-9692539 HRH1 binds HRH1 inverse agonists IEA Gallus gallus 135954 R-ALL-9692684 bilastine [extracellular region] R-HSA-9692539 https://reactome.org/PathwayBrowser/#/R-HSA-9692539 HRH1 binds HRH1 inverse agonists TAS Homo sapiens 135954 R-ALL-9692684 bilastine [extracellular region] R-MMU-9692539 https://reactome.org/PathwayBrowser/#/R-MMU-9692539 HRH1 binds HRH1 inverse agonists IEA Mus musculus 135954 R-ALL-9692684 bilastine [extracellular region] R-RNO-9692539 https://reactome.org/PathwayBrowser/#/R-RNO-9692539 HRH1 binds HRH1 inverse agonists IEA Rattus norvegicus 135954 R-ALL-9692684 bilastine [extracellular region] R-SSC-9692539 https://reactome.org/PathwayBrowser/#/R-SSC-9692539 HRH1 binds HRH1 inverse agonists IEA Sus scrofa 135954 R-ALL-9692684 bilastine [extracellular region] R-XTR-9692539 https://reactome.org/PathwayBrowser/#/R-XTR-9692539 HRH1 binds HRH1 inverse agonists IEA Xenopus tropicalis 135961 R-ALL-9718373 degarelix [extracellular region] R-BTA-9718394 https://reactome.org/PathwayBrowser/#/R-BTA-9718394 GNRHR binds GNRHR peptide antagonists IEA Bos taurus 135961 R-ALL-9718373 degarelix [extracellular region] R-CEL-9718394 https://reactome.org/PathwayBrowser/#/R-CEL-9718394 GNRHR binds GNRHR peptide antagonists IEA Caenorhabditis elegans 135961 R-ALL-9718373 degarelix [extracellular region] R-CFA-9718394 https://reactome.org/PathwayBrowser/#/R-CFA-9718394 GNRHR binds GNRHR peptide antagonists IEA Canis familiaris 135961 R-ALL-9718373 degarelix [extracellular region] R-DME-9718394 https://reactome.org/PathwayBrowser/#/R-DME-9718394 GNRHR binds GNRHR peptide antagonists IEA Drosophila melanogaster 135961 R-ALL-9718373 degarelix [extracellular region] R-DRE-9718394 https://reactome.org/PathwayBrowser/#/R-DRE-9718394 GNRHR binds GNRHR peptide antagonists IEA Danio rerio 135961 R-ALL-9718373 degarelix [extracellular region] R-GGA-9718394 https://reactome.org/PathwayBrowser/#/R-GGA-9718394 GNRHR binds GNRHR peptide antagonists IEA Gallus gallus 135961 R-ALL-9718373 degarelix [extracellular region] R-HSA-9718394 https://reactome.org/PathwayBrowser/#/R-HSA-9718394 GNRHR binds GNRHR peptide antagonists TAS Homo sapiens 135961 R-ALL-9718373 degarelix [extracellular region] R-MMU-9718394 https://reactome.org/PathwayBrowser/#/R-MMU-9718394 GNRHR binds GNRHR peptide antagonists IEA Mus musculus 135961 R-ALL-9718373 degarelix [extracellular region] R-RNO-9718394 https://reactome.org/PathwayBrowser/#/R-RNO-9718394 GNRHR binds GNRHR peptide antagonists IEA Rattus norvegicus 135961 R-ALL-9718373 degarelix [extracellular region] R-SSC-9718394 https://reactome.org/PathwayBrowser/#/R-SSC-9718394 GNRHR binds GNRHR peptide antagonists IEA Sus scrofa 135961 R-ALL-9718373 degarelix [extracellular region] R-XTR-9718394 https://reactome.org/PathwayBrowser/#/R-XTR-9718394 GNRHR binds GNRHR peptide antagonists IEA Xenopus tropicalis 135962 R-ALL-9714421 dapoxetine [extracellular region] R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 135962 R-ALL-9714421 dapoxetine [extracellular region] R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 135962 R-ALL-9714421 dapoxetine [extracellular region] R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 135962 R-ALL-9714421 dapoxetine [extracellular region] R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 135962 R-ALL-9714421 dapoxetine [extracellular region] R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 135962 R-ALL-9714421 dapoxetine [extracellular region] R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 135962 R-ALL-9714421 dapoxetine [extracellular region] R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 135962 R-ALL-9714421 dapoxetine [extracellular region] R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 135962 R-ALL-9714421 dapoxetine [extracellular region] R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 135962 R-ALL-9714421 dapoxetine [extracellular region] R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 135962 R-ALL-9714421 dapoxetine [extracellular region] R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 135962 R-ALL-9714421 dapoxetine [extracellular region] R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-BTA-9714415 https://reactome.org/PathwayBrowser/#/R-BTA-9714415 SLC6A4 binds TCAs and SSRIs IEA Bos taurus 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-CEL-9714415 https://reactome.org/PathwayBrowser/#/R-CEL-9714415 SLC6A4 binds TCAs and SSRIs IEA Caenorhabditis elegans 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-CFA-9714415 https://reactome.org/PathwayBrowser/#/R-CFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Canis familiaris 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-DME-9714415 https://reactome.org/PathwayBrowser/#/R-DME-9714415 SLC6A4 binds TCAs and SSRIs IEA Drosophila melanogaster 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-DRE-9714415 https://reactome.org/PathwayBrowser/#/R-DRE-9714415 SLC6A4 binds TCAs and SSRIs IEA Danio rerio 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-GGA-9714415 https://reactome.org/PathwayBrowser/#/R-GGA-9714415 SLC6A4 binds TCAs and SSRIs IEA Gallus gallus 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-HSA-9714415 https://reactome.org/PathwayBrowser/#/R-HSA-9714415 SLC6A4 binds TCAs and SSRIs TAS Homo sapiens 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-MMU-9714415 https://reactome.org/PathwayBrowser/#/R-MMU-9714415 SLC6A4 binds TCAs and SSRIs IEA Mus musculus 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-PFA-9714415 https://reactome.org/PathwayBrowser/#/R-PFA-9714415 SLC6A4 binds TCAs and SSRIs IEA Plasmodium falciparum 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-RNO-9714415 https://reactome.org/PathwayBrowser/#/R-RNO-9714415 SLC6A4 binds TCAs and SSRIs IEA Rattus norvegicus 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-SSC-9714415 https://reactome.org/PathwayBrowser/#/R-SSC-9714415 SLC6A4 binds TCAs and SSRIs IEA Sus scrofa 136040 R-ALL-9714403 levomilnacipran [extracellular region] R-XTR-9714415 https://reactome.org/PathwayBrowser/#/R-XTR-9714415 SLC6A4 binds TCAs and SSRIs IEA Xenopus tropicalis 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-BTA-9728150 https://reactome.org/PathwayBrowser/#/R-BTA-9728150 SLC5A2 binds gliflozins IEA Bos taurus 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-CFA-9728150 https://reactome.org/PathwayBrowser/#/R-CFA-9728150 SLC5A2 binds gliflozins IEA Canis familiaris 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-DRE-9728150 https://reactome.org/PathwayBrowser/#/R-DRE-9728150 SLC5A2 binds gliflozins IEA Danio rerio 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-HSA-9728150 https://reactome.org/PathwayBrowser/#/R-HSA-9728150 SLC5A2 binds gliflozins TAS Homo sapiens 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-MMU-9728150 https://reactome.org/PathwayBrowser/#/R-MMU-9728150 SLC5A2 binds gliflozins IEA Mus musculus 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-RNO-9728150 https://reactome.org/PathwayBrowser/#/R-RNO-9728150 SLC5A2 binds gliflozins IEA Rattus norvegicus 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-SSC-9728150 https://reactome.org/PathwayBrowser/#/R-SSC-9728150 SLC5A2 binds gliflozins IEA Sus scrofa 136041 R-ALL-9728190 tofogliflozin [extracellular region] R-XTR-9728150 https://reactome.org/PathwayBrowser/#/R-XTR-9728150 SLC5A2 binds gliflozins IEA Xenopus tropicalis 136042 R-ALL-9709176 teneligliptin [extracellular region] R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 136042 R-ALL-9709176 teneligliptin [extracellular region] R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 136042 R-ALL-9709176 teneligliptin [extracellular region] R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 136042 R-ALL-9709176 teneligliptin [extracellular region] R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 136042 R-ALL-9709176 teneligliptin [extracellular region] R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 136042 R-ALL-9709176 teneligliptin [extracellular region] R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 136042 R-ALL-9709176 teneligliptin [extracellular region] R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 136042 R-ALL-9709176 teneligliptin [extracellular region] R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 136042 R-ALL-9709176 teneligliptin [extracellular region] R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 136042 R-ALL-9709176 teneligliptin [extracellular region] R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 136042 R-ALL-9709176 teneligliptin [extracellular region] R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 136042 R-ALL-9709176 teneligliptin [extracellular region] R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 136043 R-ALL-9709172 anagliptin [extracellular region] R-BTA-9709179 https://reactome.org/PathwayBrowser/#/R-BTA-9709179 DPP4 binds DPP4 inhibitors IEA Bos taurus 136043 R-ALL-9709172 anagliptin [extracellular region] R-CEL-9709179 https://reactome.org/PathwayBrowser/#/R-CEL-9709179 DPP4 binds DPP4 inhibitors IEA Caenorhabditis elegans 136043 R-ALL-9709172 anagliptin [extracellular region] R-CFA-9709179 https://reactome.org/PathwayBrowser/#/R-CFA-9709179 DPP4 binds DPP4 inhibitors IEA Canis familiaris 136043 R-ALL-9709172 anagliptin [extracellular region] R-DME-9709179 https://reactome.org/PathwayBrowser/#/R-DME-9709179 DPP4 binds DPP4 inhibitors IEA Drosophila melanogaster 136043 R-ALL-9709172 anagliptin [extracellular region] R-DRE-9709179 https://reactome.org/PathwayBrowser/#/R-DRE-9709179 DPP4 binds DPP4 inhibitors IEA Danio rerio 136043 R-ALL-9709172 anagliptin [extracellular region] R-GGA-9709179 https://reactome.org/PathwayBrowser/#/R-GGA-9709179 DPP4 binds DPP4 inhibitors IEA Gallus gallus 136043 R-ALL-9709172 anagliptin [extracellular region] R-HSA-9709179 https://reactome.org/PathwayBrowser/#/R-HSA-9709179 DPP4 binds DPP4 inhibitors TAS Homo sapiens 136043 R-ALL-9709172 anagliptin [extracellular region] R-MMU-9709179 https://reactome.org/PathwayBrowser/#/R-MMU-9709179 DPP4 binds DPP4 inhibitors IEA Mus musculus 136043 R-ALL-9709172 anagliptin [extracellular region] R-RNO-9709179 https://reactome.org/PathwayBrowser/#/R-RNO-9709179 DPP4 binds DPP4 inhibitors IEA Rattus norvegicus 136043 R-ALL-9709172 anagliptin [extracellular region] R-SCE-9709179 https://reactome.org/PathwayBrowser/#/R-SCE-9709179 DPP4 binds DPP4 inhibitors IEA Saccharomyces cerevisiae 136043 R-ALL-9709172 anagliptin [extracellular region] R-SPO-9709179 https://reactome.org/PathwayBrowser/#/R-SPO-9709179 DPP4 binds DPP4 inhibitors IEA Schizosaccharomyces pombe 136043 R-ALL-9709172 anagliptin [extracellular region] R-SSC-9709179 https://reactome.org/PathwayBrowser/#/R-SSC-9709179 DPP4 binds DPP4 inhibitors IEA Sus scrofa 136046 R-ALL-9680440 ripasudil [cytosol] R-BTA-419049 https://reactome.org/PathwayBrowser/#/R-BTA-419049 ROCK activation by RHO IEA Bos taurus 136046 R-ALL-9680440 ripasudil [cytosol] R-BTA-9680443 https://reactome.org/PathwayBrowser/#/R-BTA-9680443 ROCK1,2 bind ROCKi IEA Bos taurus 136046 R-ALL-9680440 ripasudil [cytosol] R-CEL-419049 https://reactome.org/PathwayBrowser/#/R-CEL-419049 ROCK activation by RHO IEA Caenorhabditis elegans 136046 R-ALL-9680440 ripasudil [cytosol] R-CEL-9680443 https://reactome.org/PathwayBrowser/#/R-CEL-9680443 ROCK1,2 bind ROCKi IEA Caenorhabditis elegans 136046 R-ALL-9680440 ripasudil [cytosol] R-CFA-419049 https://reactome.org/PathwayBrowser/#/R-CFA-419049 ROCK activation by RHO IEA Canis familiaris 136046 R-ALL-9680440 ripasudil [cytosol] R-CFA-9680443 https://reactome.org/PathwayBrowser/#/R-CFA-9680443 ROCK1,2 bind ROCKi IEA Canis familiaris 136046 R-ALL-9680440 ripasudil [cytosol] R-DME-419049 https://reactome.org/PathwayBrowser/#/R-DME-419049 ROCK activation by RHO IEA Drosophila melanogaster 136046 R-ALL-9680440 ripasudil [cytosol] R-DME-9680443 https://reactome.org/PathwayBrowser/#/R-DME-9680443 ROCK1,2 bind ROCKi IEA Drosophila melanogaster 136046 R-ALL-9680440 ripasudil [cytosol] R-DRE-419049 https://reactome.org/PathwayBrowser/#/R-DRE-419049 ROCK activation by RHO IEA Danio rerio 136046 R-ALL-9680440 ripasudil [cytosol] R-DRE-9680443 https://reactome.org/PathwayBrowser/#/R-DRE-9680443 ROCK1,2 bind ROCKi IEA Danio rerio 136046 R-ALL-9680440 ripasudil [cytosol] R-GGA-419049 https://reactome.org/PathwayBrowser/#/R-GGA-419049 ROCK activation by RHO IEA Gallus gallus 136046 R-ALL-9680440 ripasudil [cytosol] R-GGA-9680443 https://reactome.org/PathwayBrowser/#/R-GGA-9680443 ROCK1,2 bind ROCKi IEA Gallus gallus 136046 R-ALL-9680440 ripasudil [cytosol] R-HSA-419049 https://reactome.org/PathwayBrowser/#/R-HSA-419049 ROCK activation by RHO TAS Homo sapiens 136046 R-ALL-9680440 ripasudil [cytosol] R-HSA-9680443 https://reactome.org/PathwayBrowser/#/R-HSA-9680443 ROCK1,2 bind ROCKi TAS Homo sapiens 136046 R-ALL-9680440 ripasudil [cytosol] R-MMU-419049 https://reactome.org/PathwayBrowser/#/R-MMU-419049 ROCK activation by RHO IEA Mus musculus 136046 R-ALL-9680440 ripasudil [cytosol] R-MMU-9680443 https://reactome.org/PathwayBrowser/#/R-MMU-9680443 ROCK1,2 bind ROCKi IEA Mus musculus 136046 R-ALL-9680440 ripasudil [cytosol] R-RNO-419049 https://reactome.org/PathwayBrowser/#/R-RNO-419049 ROCK activation by RHO IEA Rattus norvegicus 136046 R-ALL-9680440 ripasudil [cytosol] R-RNO-9680443 https://reactome.org/PathwayBrowser/#/R-RNO-9680443 ROCK1,2 bind ROCKi IEA Rattus norvegicus 136046 R-ALL-9680440 ripasudil [cytosol] R-SSC-419049 https://reactome.org/PathwayBrowser/#/R-SSC-419049 ROCK activation by RHO IEA Sus scrofa 136046 R-ALL-9680440 ripasudil [cytosol] R-SSC-9680443 https://reactome.org/PathwayBrowser/#/R-SSC-9680443 ROCK1,2 bind ROCKi IEA Sus scrofa 136046 R-ALL-9680440 ripasudil [cytosol] R-XTR-419049 https://reactome.org/PathwayBrowser/#/R-XTR-419049 ROCK activation by RHO IEA Xenopus tropicalis 136046 R-ALL-9680440 ripasudil [cytosol] R-XTR-9680443 https://reactome.org/PathwayBrowser/#/R-XTR-9680443 ROCK1,2 bind ROCKi IEA Xenopus tropicalis 136049 R-ALL-9708103 mirodenafil [cytosol] R-BTA-9708104 https://reactome.org/PathwayBrowser/#/R-BTA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Bos taurus 136049 R-ALL-9708103 mirodenafil [cytosol] R-CFA-9708104 https://reactome.org/PathwayBrowser/#/R-CFA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Canis familiaris 136049 R-ALL-9708103 mirodenafil [cytosol] R-DME-9708104 https://reactome.org/PathwayBrowser/#/R-DME-9708104 PDE5A dimer binds PDE5A inhibitors IEA Drosophila melanogaster 136049 R-ALL-9708103 mirodenafil [cytosol] R-GGA-9708104 https://reactome.org/PathwayBrowser/#/R-GGA-9708104 PDE5A dimer binds PDE5A inhibitors IEA Gallus gallus 136049 R-ALL-9708103 mirodenafil [cytosol] R-HSA-9708104 https://reactome.org/PathwayBrowser/#/R-HSA-9708104 PDE5A dimer binds PDE5A inhibitors TAS Homo sapiens 136049 R-ALL-9708103 mirodenafil [cytosol] R-MMU-9708104 https://reactome.org/PathwayBrowser/#/R-MMU-9708104 PDE5A dimer binds PDE5A inhibitors IEA Mus musculus 136049 R-ALL-9708103 mirodenafil [cytosol] R-RNO-9708104 https://reactome.org/PathwayBrowser/#/R-RNO-9708104 PDE5A dimer binds PDE5A inhibitors IEA Rattus norvegicus 136049 R-ALL-9708103 mirodenafil [cytosol] R-SSC-9708104 https://reactome.org/PathwayBrowser/#/R-SSC-9708104 PDE5A dimer binds PDE5A inhibitors IEA Sus scrofa 136049 R-ALL-9708103 mirodenafil [cytosol] R-XTR-9708104 https://reactome.org/PathwayBrowser/#/R-XTR-9708104 PDE5A dimer binds PDE5A inhibitors IEA Xenopus tropicalis 136056 R-ALL-9022650 18(S)-RvE2 [cytosol] R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 136056 R-ALL-9022650 18(S)-RvE2 [cytosol] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 136056 R-ALL-9024003 18(S)-RvE2 [extracellular region] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-BTA-8862700 https://reactome.org/PathwayBrowser/#/R-BTA-8862700 CMKLR1 binds Resolvin E1 IEA Bos taurus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-BTA-9023968 https://reactome.org/PathwayBrowser/#/R-BTA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Bos taurus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-CFA-8862700 https://reactome.org/PathwayBrowser/#/R-CFA-8862700 CMKLR1 binds Resolvin E1 IEA Canis familiaris 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-CFA-9023968 https://reactome.org/PathwayBrowser/#/R-CFA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Canis familiaris 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-DME-9023968 https://reactome.org/PathwayBrowser/#/R-DME-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Drosophila melanogaster 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-DRE-9023968 https://reactome.org/PathwayBrowser/#/R-DRE-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Danio rerio 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-GGA-8862700 https://reactome.org/PathwayBrowser/#/R-GGA-8862700 CMKLR1 binds Resolvin E1 IEA Gallus gallus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-GGA-9023968 https://reactome.org/PathwayBrowser/#/R-GGA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Gallus gallus 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-HSA-8862700 https://reactome.org/PathwayBrowser/#/R-HSA-8862700 CMKLR1 binds Resolvin E1 TAS Homo sapiens 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-HSA-9023968 https://reactome.org/PathwayBrowser/#/R-HSA-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 TAS Homo sapiens 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-MMU-8862700 https://reactome.org/PathwayBrowser/#/R-MMU-8862700 CMKLR1 binds Resolvin E1 IEA Mus musculus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-MMU-9023968 https://reactome.org/PathwayBrowser/#/R-MMU-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Mus musculus 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-RNO-8862700 https://reactome.org/PathwayBrowser/#/R-RNO-8862700 CMKLR1 binds Resolvin E1 IEA Rattus norvegicus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-RNO-9023968 https://reactome.org/PathwayBrowser/#/R-RNO-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Rattus norvegicus 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-SSC-8862700 https://reactome.org/PathwayBrowser/#/R-SSC-8862700 CMKLR1 binds Resolvin E1 IEA Sus scrofa 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-SSC-9023968 https://reactome.org/PathwayBrowser/#/R-SSC-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Sus scrofa 136057 R-ALL-9023991 18(S)-RvE1 [extracellular region] R-XTR-8862700 https://reactome.org/PathwayBrowser/#/R-XTR-8862700 CMKLR1 binds Resolvin E1 IEA Xenopus tropicalis 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 136057 R-ALL-9022660 18(S)-RvE1 [cytosol] R-XTR-9023968 https://reactome.org/PathwayBrowser/#/R-XTR-9023968 HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 IEA Xenopus tropicalis 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 136525 R-ALL-9027049 14(R)-HDHA [cytosol] R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 136526 R-ALL-9027029 14(S)-HDHA [cytosol] R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 136529 R-ALL-9027040 MaR-L1 [cytosol] R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 136529 R-ALL-9027040 MaR-L1 [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136529 R-ALL-9031797 MaR-L1 [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136530 R-ALL-9027045 MaR-L2 [cytosol] R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 136530 R-ALL-9027045 MaR-L2 [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136530 R-ALL-9031799 MaR-L2 [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136533 R-ALL-9031810 14(S),21(R)-diHDHA [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 136533 R-ALL-9027303 14(S),21(R)-diHDHA [cytosol] R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136534 R-ALL-9031820 14(S),21(S)-diHDHA [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 136534 R-ALL-9027322 14(S),21(S)-diHDHA [cytosol] R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136535 R-ALL-9031806 14(R),21(R)-diHDHA [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 136535 R-ALL-9027308 14(R),21(R)-diHDHA [cytosol] R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136536 R-ALL-9031805 14(R),21(S)-diHDHA [extracellular region] R-HSA-9031803 https://reactome.org/PathwayBrowser/#/R-HSA-9031803 Maresin-like SPMs translocate from cytosol to extracellular region TAS Homo sapiens 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 136536 R-ALL-9027305 14(R),21(S)-diHDHA [cytosol] R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 136539 R-ALL-2142828 11dh-TXB2 [endoplasmic reticulum lumen] R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-BTA-176609 https://reactome.org/PathwayBrowser/#/R-BTA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Bos taurus 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-CFA-176609 https://reactome.org/PathwayBrowser/#/R-CFA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Canis familiaris 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-DME-176609 https://reactome.org/PathwayBrowser/#/R-DME-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Drosophila melanogaster 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-DRE-176609 https://reactome.org/PathwayBrowser/#/R-DRE-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Danio rerio 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-GGA-176609 https://reactome.org/PathwayBrowser/#/R-GGA-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Gallus gallus 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-HSA-176609 https://reactome.org/PathwayBrowser/#/R-HSA-176609 cholesterol + PAPS => cholesterol sulfate + PAP TAS Homo sapiens 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-MMU-176609 https://reactome.org/PathwayBrowser/#/R-MMU-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Mus musculus 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-RNO-176609 https://reactome.org/PathwayBrowser/#/R-RNO-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Rattus norvegicus 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-SSC-176609 https://reactome.org/PathwayBrowser/#/R-SSC-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Sus scrofa 136579 R-ALL-176618 cholesterol sulfate [cytosol] R-XTR-176609 https://reactome.org/PathwayBrowser/#/R-XTR-176609 cholesterol + PAPS => cholesterol sulfate + PAP IEA Xenopus tropicalis 136721 R-HSA-9670084 TERRA [nucleoplasm] R-HSA-9670149 https://reactome.org/PathwayBrowser/#/R-HSA-9670149 TERRA transcription TAS Homo sapiens 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 136806 R-ALL-9757308 3,5-dihydroxyanisole [extracellular region] R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 136896 R-ALL-9935262 GpppN [nucleoplasm] R-HSA-9935319 https://reactome.org/PathwayBrowser/#/R-HSA-9935319 DXO decaps incompletely capped RNA (GpppN-RNA) IEA Homo sapiens 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-BTA-4419978 https://reactome.org/PathwayBrowser/#/R-BTA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Bos taurus 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-CEL-4419978 https://reactome.org/PathwayBrowser/#/R-CEL-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Caenorhabditis elegans 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-CFA-4419978 https://reactome.org/PathwayBrowser/#/R-CFA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Canis familiaris 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-DDI-4419978 https://reactome.org/PathwayBrowser/#/R-DDI-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Dictyostelium discoideum 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-DME-4419978 https://reactome.org/PathwayBrowser/#/R-DME-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Drosophila melanogaster 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-DRE-4419978 https://reactome.org/PathwayBrowser/#/R-DRE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Danio rerio 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-GGA-4419978 https://reactome.org/PathwayBrowser/#/R-GGA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Gallus gallus 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-HSA-4419978 https://reactome.org/PathwayBrowser/#/R-HSA-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP TAS Homo sapiens 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-MMU-4419978 https://reactome.org/PathwayBrowser/#/R-MMU-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Mus musculus 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-RNO-4419978 https://reactome.org/PathwayBrowser/#/R-RNO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Rattus norvegicus 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-SCE-4419978 https://reactome.org/PathwayBrowser/#/R-SCE-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Saccharomyces cerevisiae 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-SPO-4419978 https://reactome.org/PathwayBrowser/#/R-SPO-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Schizosaccharomyces pombe 136960 R-ALL-4419982 pPPP [cytoplasmic side of endoplasmic reticulum membrane] R-SSC-4419978 https://reactome.org/PathwayBrowser/#/R-SSC-4419978 DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-BTA-5694494 https://reactome.org/PathwayBrowser/#/R-BTA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-BTA-6788597 https://reactome.org/PathwayBrowser/#/R-BTA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13705 R-ALL-29666 ACA [cytosol] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13705 R-ALL-29666 ACA [cytosol] R-CEL-5694494 https://reactome.org/PathwayBrowser/#/R-CEL-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Caenorhabditis elegans 13705 R-ALL-29666 ACA [cytosol] R-CEL-6788597 https://reactome.org/PathwayBrowser/#/R-CEL-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Caenorhabditis elegans 13705 R-ALL-29666 ACA [cytosol] R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 13705 R-ALL-29666 ACA [cytosol] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13705 R-ALL-29666 ACA [cytosol] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13705 R-ALL-29666 ACA [cytosol] R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 13705 R-ALL-29666 ACA [cytosol] R-CFA-6788597 https://reactome.org/PathwayBrowser/#/R-CFA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Canis familiaris 13705 R-ALL-29666 ACA [cytosol] R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 13705 R-ALL-29666 ACA [cytosol] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13705 R-ALL-29666 ACA [cytosol] R-DDI-6788597 https://reactome.org/PathwayBrowser/#/R-DDI-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Dictyostelium discoideum 13705 R-ALL-29666 ACA [cytosol] R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 13705 R-ALL-29666 ACA [cytosol] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13705 R-ALL-29666 ACA [cytosol] R-DME-6788597 https://reactome.org/PathwayBrowser/#/R-DME-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Drosophila melanogaster 13705 R-ALL-29666 ACA [cytosol] R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 13705 R-ALL-29666 ACA [cytosol] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13705 R-ALL-29666 ACA [cytosol] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 13705 R-ALL-29666 ACA [cytosol] R-DRE-5694494 https://reactome.org/PathwayBrowser/#/R-DRE-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Danio rerio 13705 R-ALL-29666 ACA [cytosol] R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 13705 R-ALL-29666 ACA [cytosol] R-DRE-6788597 https://reactome.org/PathwayBrowser/#/R-DRE-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Danio rerio 13705 R-ALL-29666 ACA [cytosol] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-GGA-5694494 https://reactome.org/PathwayBrowser/#/R-GGA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-GGA-6788597 https://reactome.org/PathwayBrowser/#/R-GGA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13705 R-ALL-29666 ACA [cytosol] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-HSA-5694494 https://reactome.org/PathwayBrowser/#/R-HSA-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-HSA-6788597 https://reactome.org/PathwayBrowser/#/R-HSA-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13705 R-ALL-29666 ACA [cytosol] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-MMU-5694494 https://reactome.org/PathwayBrowser/#/R-MMU-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-MMU-6788597 https://reactome.org/PathwayBrowser/#/R-MMU-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13705 R-ALL-29666 ACA [cytosol] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-RNO-5694494 https://reactome.org/PathwayBrowser/#/R-RNO-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-RNO-6788597 https://reactome.org/PathwayBrowser/#/R-RNO-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13705 R-ALL-29666 ACA [cytosol] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-SSC-5694494 https://reactome.org/PathwayBrowser/#/R-SSC-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-SSC-6788597 https://reactome.org/PathwayBrowser/#/R-SSC-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13705 R-ALL-29666 ACA [cytosol] R-XTR-5694494 https://reactome.org/PathwayBrowser/#/R-XTR-5694494 AACS ligates CoA-SH to ACA, forming ACA-CoA IEA Xenopus tropicalis 13705 R-ALL-29666 ACA [cytosol] R-XTR-6788597 https://reactome.org/PathwayBrowser/#/R-XTR-6788597 HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA IEA Xenopus tropicalis 13705 R-ALL-29666 ACA [cytosol] R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 13705 R-ALL-29666 ACA [cytosol] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-9749583 https://reactome.org/PathwayBrowser/#/R-BTA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Bos taurus 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-BTA-9749583 https://reactome.org/PathwayBrowser/#/R-BTA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-9749590 https://reactome.org/PathwayBrowser/#/R-BTA-9749590 ASA- acetylates ALB IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-9749607 https://reactome.org/PathwayBrowser/#/R-BTA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Bos taurus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-BTA-9749607 https://reactome.org/PathwayBrowser/#/R-BTA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 13719 R-ALL-9749598 ASA- [extracellular region] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-ALL-9749598 ASA- [extracellular region] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 13719 R-ALL-9749598 ASA- [extracellular region] R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-CEL-9749583 https://reactome.org/PathwayBrowser/#/R-CEL-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Caenorhabditis elegans 13719 R-ALL-9749598 ASA- [extracellular region] R-CEL-9749607 https://reactome.org/PathwayBrowser/#/R-CEL-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Caenorhabditis elegans 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CEL-9749607 https://reactome.org/PathwayBrowser/#/R-CEL-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Caenorhabditis elegans 13719 R-ALL-9749598 ASA- [extracellular region] R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 13719 R-ALL-9749598 ASA- [extracellular region] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-ALL-9749598 ASA- [extracellular region] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 13719 R-ALL-9749598 ASA- [extracellular region] R-CFA-9749590 https://reactome.org/PathwayBrowser/#/R-CFA-9749590 ASA- acetylates ALB IEA Canis familiaris 13719 R-ALL-9749598 ASA- [extracellular region] R-CFA-9749607 https://reactome.org/PathwayBrowser/#/R-CFA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Canis familiaris 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-CFA-9749607 https://reactome.org/PathwayBrowser/#/R-CFA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Canis familiaris 13719 R-ALL-9749598 ASA- [extracellular region] R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 13719 R-ALL-9749598 ASA- [extracellular region] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-ALL-9749598 ASA- [extracellular region] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 13719 R-ALL-9749598 ASA- [extracellular region] R-DME-9749583 https://reactome.org/PathwayBrowser/#/R-DME-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Drosophila melanogaster 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-DME-9749583 https://reactome.org/PathwayBrowser/#/R-DME-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Drosophila melanogaster 13719 R-ALL-9749598 ASA- [extracellular region] R-DME-9749607 https://reactome.org/PathwayBrowser/#/R-DME-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Drosophila melanogaster 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-DME-9749607 https://reactome.org/PathwayBrowser/#/R-DME-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Drosophila melanogaster 13719 R-ALL-9749598 ASA- [extracellular region] R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 13719 R-ALL-9749598 ASA- [extracellular region] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 13719 R-ALL-9749598 ASA- [extracellular region] R-DRE-9749583 https://reactome.org/PathwayBrowser/#/R-DRE-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Danio rerio 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-DRE-9749583 https://reactome.org/PathwayBrowser/#/R-DRE-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Danio rerio 13719 R-ALL-9749598 ASA- [extracellular region] R-DRE-9749607 https://reactome.org/PathwayBrowser/#/R-DRE-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Danio rerio 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-DRE-9749607 https://reactome.org/PathwayBrowser/#/R-DRE-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Danio rerio 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-9749583 https://reactome.org/PathwayBrowser/#/R-GGA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Gallus gallus 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-GGA-9749583 https://reactome.org/PathwayBrowser/#/R-GGA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-9749590 https://reactome.org/PathwayBrowser/#/R-GGA-9749590 ASA- acetylates ALB IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-9749607 https://reactome.org/PathwayBrowser/#/R-GGA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Gallus gallus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-GGA-9749607 https://reactome.org/PathwayBrowser/#/R-GGA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9749583 https://reactome.org/PathwayBrowser/#/R-HSA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes TAS Homo sapiens 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-HSA-9749583 https://reactome.org/PathwayBrowser/#/R-HSA-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9749590 https://reactome.org/PathwayBrowser/#/R-HSA-9749590 ASA- acetylates ALB TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9749607 https://reactome.org/PathwayBrowser/#/R-HSA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells TAS Homo sapiens 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-HSA-9749607 https://reactome.org/PathwayBrowser/#/R-HSA-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-HSA-9757438 https://reactome.org/PathwayBrowser/#/R-HSA-9757438 ASA- translocates from cytosol to ER lumen of GI cells TAS Homo sapiens 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-HSA-9757438 https://reactome.org/PathwayBrowser/#/R-HSA-9757438 ASA- translocates from cytosol to ER lumen of GI cells TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-HSA-9757441 https://reactome.org/PathwayBrowser/#/R-HSA-9757441 ASA- (GI) translocates from cytosol to extracellular region TAS Homo sapiens 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-HSA-9757441 https://reactome.org/PathwayBrowser/#/R-HSA-9757441 ASA- (GI) translocates from cytosol to extracellular region TAS Homo sapiens 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-HSA-9757451 https://reactome.org/PathwayBrowser/#/R-HSA-9757451 ASA-,ST translocate from cytosol to ER lumen of hepatocytes TAS Homo sapiens 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-HSA-9757451 https://reactome.org/PathwayBrowser/#/R-HSA-9757451 ASA-,ST translocate from cytosol to ER lumen of hepatocytes TAS Homo sapiens 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-9749583 https://reactome.org/PathwayBrowser/#/R-MMU-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Mus musculus 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-MMU-9749583 https://reactome.org/PathwayBrowser/#/R-MMU-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-9749590 https://reactome.org/PathwayBrowser/#/R-MMU-9749590 ASA- acetylates ALB IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-9749607 https://reactome.org/PathwayBrowser/#/R-MMU-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Mus musculus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-MMU-9749607 https://reactome.org/PathwayBrowser/#/R-MMU-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-9749583 https://reactome.org/PathwayBrowser/#/R-RNO-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Rattus norvegicus 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-RNO-9749583 https://reactome.org/PathwayBrowser/#/R-RNO-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-9749590 https://reactome.org/PathwayBrowser/#/R-RNO-9749590 ASA- acetylates ALB IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-9749607 https://reactome.org/PathwayBrowser/#/R-RNO-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Rattus norvegicus 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-RNO-9749607 https://reactome.org/PathwayBrowser/#/R-RNO-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 13719 R-ALL-9749582 ASA- (GI cell) [endoplasmic reticulum lumen] R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 13719 R-ALL-9749598 ASA- [extracellular region] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-ALL-9749598 ASA- [extracellular region] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 13719 R-ALL-9749598 ASA- [extracellular region] R-SSC-9749583 https://reactome.org/PathwayBrowser/#/R-SSC-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Sus scrofa 13719 R-ALL-9749789 ASA- (hepatocyte) [cytosol] R-SSC-9749583 https://reactome.org/PathwayBrowser/#/R-SSC-9749583 SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes IEA Sus scrofa 13719 R-ALL-9749598 ASA- [extracellular region] R-SSC-9749590 https://reactome.org/PathwayBrowser/#/R-SSC-9749590 ASA- acetylates ALB IEA Sus scrofa 13719 R-ALL-9749598 ASA- [extracellular region] R-SSC-9749607 https://reactome.org/PathwayBrowser/#/R-SSC-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Sus scrofa 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-SSC-9749607 https://reactome.org/PathwayBrowser/#/R-SSC-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Sus scrofa 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 13719 R-ALL-9749598 ASA- [extracellular region] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 13719 R-ALL-9749598 ASA- [extracellular region] R-XTR-9749590 https://reactome.org/PathwayBrowser/#/R-XTR-9749590 ASA- acetylates ALB IEA Xenopus tropicalis 13719 R-ALL-9749598 ASA- [extracellular region] R-XTR-9749607 https://reactome.org/PathwayBrowser/#/R-XTR-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Xenopus tropicalis 13719 R-ALL-9749785 ASA- (GI cell) [cytosol] R-XTR-9749607 https://reactome.org/PathwayBrowser/#/R-XTR-9749607 SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells IEA Xenopus tropicalis 13719 R-ALL-9749598 ASA- [extracellular region] R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 13719 R-ALL-9749795 ASA- (hepatocyte) [endoplasmic reticulum lumen] R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 137218 R-HSA-110201 3meA-dsDNA [nucleoplasm] R-HSA-110238 https://reactome.org/PathwayBrowser/#/R-HSA-110238 MPG glycosylase mediated recognition and binding of 3-methyladenine TAS Homo sapiens 137218 R-HSA-110201 3meA-dsDNA [nucleoplasm] R-HSA-110248 https://reactome.org/PathwayBrowser/#/R-HSA-110248 Cleavage of 3-methyladenine by MPG glycosylase TAS Homo sapiens 137218 R-HSA-110201 3meA-dsDNA [nucleoplasm] R-HSA-9730736 https://reactome.org/PathwayBrowser/#/R-HSA-9730736 Monofunctional chemotherapeutic alkylating drugs produce 3-methyladenine in dsDNA IEA Homo sapiens 137376 R-ALL-9635506 LCFA adenylate ester [cytosol] R-MTU-9635428 https://reactome.org/PathwayBrowser/#/R-MTU-9635428 FadD26, FadD28 transfer LCFA adenylate ester to Pks5 TAS Mycobacterium tuberculosis 137376 R-ALL-9635506 LCFA adenylate ester [cytosol] R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 137376 R-ALL-9635506 LCFA adenylate ester [cytosol] R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 137407 R-ALL-9026761 MCTR1 [cytosol] R-BTA-9026777 https://reactome.org/PathwayBrowser/#/R-BTA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 137407 R-ALL-9026761 MCTR1 [cytosol] R-BTA-9026780 https://reactome.org/PathwayBrowser/#/R-BTA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Bos taurus 137407 R-ALL-9026761 MCTR1 [cytosol] R-CFA-9026777 https://reactome.org/PathwayBrowser/#/R-CFA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 137407 R-ALL-9026761 MCTR1 [cytosol] R-CFA-9026780 https://reactome.org/PathwayBrowser/#/R-CFA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Canis familiaris 137407 R-ALL-9026761 MCTR1 [cytosol] R-DDI-9026780 https://reactome.org/PathwayBrowser/#/R-DDI-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Dictyostelium discoideum 137407 R-ALL-9026761 MCTR1 [cytosol] R-DRE-9026777 https://reactome.org/PathwayBrowser/#/R-DRE-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Danio rerio 137407 R-ALL-9026761 MCTR1 [cytosol] R-GGA-9026777 https://reactome.org/PathwayBrowser/#/R-GGA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 137407 R-ALL-9026761 MCTR1 [cytosol] R-GGA-9026780 https://reactome.org/PathwayBrowser/#/R-GGA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Gallus gallus 137407 R-ALL-9026761 MCTR1 [cytosol] R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 137407 R-ALL-9026761 MCTR1 [cytosol] R-HSA-9026777 https://reactome.org/PathwayBrowser/#/R-HSA-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 137407 R-ALL-9026761 MCTR1 [cytosol] R-HSA-9026780 https://reactome.org/PathwayBrowser/#/R-HSA-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 TAS Homo sapiens 137407 R-ALL-9026761 MCTR1 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137407 R-ALL-9031850 MCTR1 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137407 R-ALL-9026761 MCTR1 [cytosol] R-MMU-9026777 https://reactome.org/PathwayBrowser/#/R-MMU-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 137407 R-ALL-9026761 MCTR1 [cytosol] R-MMU-9026780 https://reactome.org/PathwayBrowser/#/R-MMU-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Mus musculus 137407 R-ALL-9026761 MCTR1 [cytosol] R-RNO-9026777 https://reactome.org/PathwayBrowser/#/R-RNO-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 137407 R-ALL-9026761 MCTR1 [cytosol] R-RNO-9026780 https://reactome.org/PathwayBrowser/#/R-RNO-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Rattus norvegicus 137407 R-ALL-9026761 MCTR1 [cytosol] R-SSC-9026777 https://reactome.org/PathwayBrowser/#/R-SSC-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 137407 R-ALL-9026761 MCTR1 [cytosol] R-SSC-9026780 https://reactome.org/PathwayBrowser/#/R-SSC-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Sus scrofa 137407 R-ALL-9026761 MCTR1 [cytosol] R-XTR-9026777 https://reactome.org/PathwayBrowser/#/R-XTR-9026777 GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 137407 R-ALL-9026761 MCTR1 [cytosol] R-XTR-9026780 https://reactome.org/PathwayBrowser/#/R-XTR-9026780 LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 IEA Xenopus tropicalis 137408 R-ALL-9026760 MCTR2 [cytosol] R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 137408 R-ALL-9026760 MCTR2 [cytosol] R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 137408 R-ALL-9026760 MCTR2 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137408 R-ALL-9031846 MCTR2 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137410 R-ALL-9026776 MCTR3 [cytosol] R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 137410 R-ALL-9026776 MCTR3 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137410 R-ALL-9031851 MCTR3 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 137442 R-ALL-9025011 MaR2 [cytosol] R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 137442 R-ALL-9025011 MaR2 [cytosol] R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 137442 R-ALL-9025011 MaR2 [cytosol] R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 137442 R-ALL-9025011 MaR2 [cytosol] R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 137442 R-ALL-9025011 MaR2 [cytosol] R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 137442 R-ALL-9025011 MaR2 [cytosol] R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 137442 R-ALL-9025011 MaR2 [cytosol] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 137442 R-ALL-9031817 MaR2 [extracellular region] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 137442 R-ALL-9025011 MaR2 [cytosol] R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 137442 R-ALL-9025011 MaR2 [cytosol] R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 137442 R-ALL-9025011 MaR2 [cytosol] R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 137442 R-ALL-9025011 MaR2 [cytosol] R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 137442 R-ALL-9025011 MaR2 [cytosol] R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 137981 R-ALL-111370 AIR [cytosol] R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 137981 R-ALL-111370 AIR [cytosol] R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 137981 R-ALL-111370 AIR [cytosol] R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 137981 R-ALL-111370 AIR [cytosol] R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 137981 R-ALL-111370 AIR [cytosol] R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 137981 R-ALL-111370 AIR [cytosol] R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 137981 R-ALL-111370 AIR [cytosol] R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 137981 R-ALL-111370 AIR [cytosol] R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 137981 R-ALL-111370 AIR [cytosol] R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 137981 R-ALL-111370 AIR [cytosol] R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 137981 R-ALL-111370 AIR [cytosol] R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 137981 R-ALL-111370 AIR [cytosol] R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 137981 R-ALL-111370 AIR [cytosol] R-GGA-419214 https://reactome.org/PathwayBrowser/#/R-GGA-419214 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) TAS Gallus gallus 137981 R-ALL-111370 AIR [cytosol] R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 137981 R-ALL-111370 AIR [cytosol] R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 137981 R-ALL-111370 AIR [cytosol] R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 137981 R-ALL-111370 AIR [cytosol] R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 137981 R-ALL-111370 AIR [cytosol] R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 137981 R-ALL-111370 AIR [cytosol] R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 137981 R-ALL-111370 AIR [cytosol] R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 137981 R-ALL-111370 AIR [cytosol] R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 137981 R-ALL-111370 AIR [cytosol] R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 137981 R-ALL-111370 AIR [cytosol] R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 137981 R-ALL-111370 AIR [cytosol] R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 137981 R-ALL-111370 AIR [cytosol] R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 137981 R-ALL-111370 AIR [cytosol] R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 137981 R-ALL-111370 AIR [cytosol] R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 138170 R-ALL-9013543 sulfanegen [mitochondrial matrix] R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138179 R-ALL-9024600 AT-RvD1 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138179 R-ALL-9024603 AT-RvD1 [cytosol] R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138249 R-ALL-9025000 MaR1 [cytosol] R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 138249 R-ALL-9025000 MaR1 [cytosol] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 138249 R-ALL-9031818 MaR1 [extracellular region] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-BTA-390393 https://reactome.org/PathwayBrowser/#/R-BTA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Bos taurus 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-BTA-5696007 https://reactome.org/PathwayBrowser/#/R-BTA-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Bos taurus 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-BTA-9914143 https://reactome.org/PathwayBrowser/#/R-BTA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Bos taurus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-CEL-390393 https://reactome.org/PathwayBrowser/#/R-CEL-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Caenorhabditis elegans 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-CEL-9914143 https://reactome.org/PathwayBrowser/#/R-CEL-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Caenorhabditis elegans 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-CFA-390393 https://reactome.org/PathwayBrowser/#/R-CFA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Canis familiaris 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-CFA-5695957 https://reactome.org/PathwayBrowser/#/R-CFA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Canis familiaris 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-CFA-9914143 https://reactome.org/PathwayBrowser/#/R-CFA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Canis familiaris 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-DDI-390393 https://reactome.org/PathwayBrowser/#/R-DDI-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Dictyostelium discoideum 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-DDI-5695957 https://reactome.org/PathwayBrowser/#/R-DDI-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Dictyostelium discoideum 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-DDI-5696007 https://reactome.org/PathwayBrowser/#/R-DDI-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Dictyostelium discoideum 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-DME-390393 https://reactome.org/PathwayBrowser/#/R-DME-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Drosophila melanogaster 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-DME-5695957 https://reactome.org/PathwayBrowser/#/R-DME-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Drosophila melanogaster 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-DME-5696007 https://reactome.org/PathwayBrowser/#/R-DME-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Drosophila melanogaster 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-DME-9914143 https://reactome.org/PathwayBrowser/#/R-DME-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Drosophila melanogaster 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-GGA-5695957 https://reactome.org/PathwayBrowser/#/R-GGA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Gallus gallus 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-GGA-9914143 https://reactome.org/PathwayBrowser/#/R-GGA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Gallus gallus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-HSA-390393 https://reactome.org/PathwayBrowser/#/R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA TAS Homo sapiens 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-HSA-5695957 https://reactome.org/PathwayBrowser/#/R-HSA-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA TAS Homo sapiens 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-HSA-5696007 https://reactome.org/PathwayBrowser/#/R-HSA-5696007 ACSF3 ligates CoA-SH to VLCFA TAS Homo sapiens 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-HSA-8875077 https://reactome.org/PathwayBrowser/#/R-HSA-8875077 SLC27A3 ligates CoA-SH to VLCFA IEA Homo sapiens 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-HSA-9914143 https://reactome.org/PathwayBrowser/#/R-HSA-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH TAS Homo sapiens 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-MMU-390393 https://reactome.org/PathwayBrowser/#/R-MMU-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Mus musculus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-MMU-5695957 https://reactome.org/PathwayBrowser/#/R-MMU-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Mus musculus 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-MMU-5696007 https://reactome.org/PathwayBrowser/#/R-MMU-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Mus musculus 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-MMU-8875095 https://reactome.org/PathwayBrowser/#/R-MMU-8875095 Slc27a3 ligates CoA to VLCFA TAS Mus musculus 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-MMU-9914143 https://reactome.org/PathwayBrowser/#/R-MMU-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Mus musculus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-RNO-390393 https://reactome.org/PathwayBrowser/#/R-RNO-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Rattus norvegicus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-RNO-5695957 https://reactome.org/PathwayBrowser/#/R-RNO-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Rattus norvegicus 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-RNO-5696007 https://reactome.org/PathwayBrowser/#/R-RNO-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Rattus norvegicus 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-RNO-9914143 https://reactome.org/PathwayBrowser/#/R-RNO-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Rattus norvegicus 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-SCE-390393 https://reactome.org/PathwayBrowser/#/R-SCE-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Saccharomyces cerevisiae 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-SCE-9914143 https://reactome.org/PathwayBrowser/#/R-SCE-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Saccharomyces cerevisiae 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-SSC-390393 https://reactome.org/PathwayBrowser/#/R-SSC-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Sus scrofa 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-SSC-5695957 https://reactome.org/PathwayBrowser/#/R-SSC-5695957 ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA IEA Sus scrofa 138261 R-ALL-5696003 VLCFA-CoA [mitochondrial matrix] R-SSC-5696007 https://reactome.org/PathwayBrowser/#/R-SSC-5696007 ACSF3 ligates CoA-SH to VLCFA IEA Sus scrofa 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-SSC-9914143 https://reactome.org/PathwayBrowser/#/R-SSC-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Sus scrofa 138261 R-ALL-5695971 VLCFA-CoA [cytosol] R-XTR-390393 https://reactome.org/PathwayBrowser/#/R-XTR-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Xenopus tropicalis 138261 R-ALL-9914131 VLCFA-CoA [peroxisomal matrix] R-XTR-9914143 https://reactome.org/PathwayBrowser/#/R-XTR-9914143 SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH IEA Xenopus tropicalis 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 138387 R-ALL-9020583 18(S)-HpEPE [cytosol] R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-BTA-9728748 https://reactome.org/PathwayBrowser/#/R-BTA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Bos taurus 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-CFA-9728748 https://reactome.org/PathwayBrowser/#/R-CFA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Canis familiaris 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-DRE-9728748 https://reactome.org/PathwayBrowser/#/R-DRE-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Danio rerio 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-GGA-9728748 https://reactome.org/PathwayBrowser/#/R-GGA-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Gallus gallus 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-HSA-9728747 https://reactome.org/PathwayBrowser/#/R-HSA-9728747 GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 IEA Homo sapiens 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-HSA-9728748 https://reactome.org/PathwayBrowser/#/R-HSA-9728748 Bitter compound binds bitter taste receptor (TAS2R) TAS Homo sapiens 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-HSA-9728752 https://reactome.org/PathwayBrowser/#/R-HSA-9728752 TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding IEA Homo sapiens 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-MMU-9728748 https://reactome.org/PathwayBrowser/#/R-MMU-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Mus musculus 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-RNO-9728748 https://reactome.org/PathwayBrowser/#/R-RNO-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Rattus norvegicus 138412 R-ALL-9728962 diphenylthiourea [extracellular region] R-SSC-9728748 https://reactome.org/PathwayBrowser/#/R-SSC-9728748 Bitter compound binds bitter taste receptor (TAS2R) IEA Sus scrofa 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138477 R-ALL-9024005 18(S)-RvE3 [extracellular region] R-HSA-9023980 https://reactome.org/PathwayBrowser/#/R-HSA-9023980 18(S)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-RNO-9020610 https://reactome.org/PathwayBrowser/#/R-RNO-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Rattus norvegicus 138477 R-ALL-9022679 18(S)-RvE3 [cytosol] R-SSC-9020610 https://reactome.org/PathwayBrowser/#/R-SSC-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Sus scrofa 138488 R-ALL-9687693 alsterpaullone [cytosol] R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 138488 R-ALL-9687693 alsterpaullone [cytosol] R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 138488 R-ALL-9687693 alsterpaullone [cytosol] R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-RNO-9018859 https://reactome.org/PathwayBrowser/#/R-RNO-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Rattus norvegicus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-SSC-9018859 https://reactome.org/PathwayBrowser/#/R-SSC-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Sus scrofa 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-XTR-9018859 https://reactome.org/PathwayBrowser/#/R-XTR-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Xenopus tropicalis 138490 R-ALL-9022655 5S,6S-epoxy-18(S)-HEPE [cytosol] R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-BTA-9018907 https://reactome.org/PathwayBrowser/#/R-BTA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Bos taurus 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-CFA-9018907 https://reactome.org/PathwayBrowser/#/R-CFA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Canis familiaris 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-DDI-9018907 https://reactome.org/PathwayBrowser/#/R-DDI-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Dictyostelium discoideum 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-DRE-9018907 https://reactome.org/PathwayBrowser/#/R-DRE-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Danio rerio 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-HSA-9018907 https://reactome.org/PathwayBrowser/#/R-HSA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 TAS Homo sapiens 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138542 R-ALL-9023987 (18R)-resolvin E3 [extracellular region] R-HSA-9023983 https://reactome.org/PathwayBrowser/#/R-HSA-9023983 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region TAS Homo sapiens 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-MMU-9018907 https://reactome.org/PathwayBrowser/#/R-MMU-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Mus musculus 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-RNO-9018907 https://reactome.org/PathwayBrowser/#/R-RNO-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Rattus norvegicus 138542 R-ALL-9023644 (18R)-resolvin E3 [cytosol] R-SSC-9018907 https://reactome.org/PathwayBrowser/#/R-SSC-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Sus scrofa 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-RNO-9018894 https://reactome.org/PathwayBrowser/#/R-RNO-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Rattus norvegicus 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-SSC-9018894 https://reactome.org/PathwayBrowser/#/R-SSC-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Sus scrofa 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 138563 R-ALL-9023708 5S,6S-epoxy-18(R)-HEPE [cytosol] R-XTR-9018894 https://reactome.org/PathwayBrowser/#/R-XTR-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Xenopus tropicalis 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-RNO-9018880 https://reactome.org/PathwayBrowser/#/R-RNO-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Rattus norvegicus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-SSC-9018880 https://reactome.org/PathwayBrowser/#/R-SSC-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Sus scrofa 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 138565 R-ALL-9023653 18(R)-HpEPE [cytosol] R-XTR-9018880 https://reactome.org/PathwayBrowser/#/R-XTR-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Xenopus tropicalis 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-RNO-9020261 https://reactome.org/PathwayBrowser/#/R-RNO-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Rattus norvegicus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-SSC-9020261 https://reactome.org/PathwayBrowser/#/R-SSC-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Sus scrofa 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 138590 R-ALL-9024522 17(R)-Hp-DHA [cytosol] R-XTR-9020261 https://reactome.org/PathwayBrowser/#/R-XTR-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Xenopus tropicalis 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-BTA-9020259 https://reactome.org/PathwayBrowser/#/R-BTA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Bos taurus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-CFA-9020259 https://reactome.org/PathwayBrowser/#/R-CFA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Canis familiaris 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-DDI-9020259 https://reactome.org/PathwayBrowser/#/R-DDI-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-DRE-9020259 https://reactome.org/PathwayBrowser/#/R-DRE-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Danio rerio 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-GGA-9020259 https://reactome.org/PathwayBrowser/#/R-GGA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Gallus gallus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9020259 https://reactome.org/PathwayBrowser/#/R-HSA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA TAS Homo sapiens 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-MMU-9020259 https://reactome.org/PathwayBrowser/#/R-MMU-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Mus musculus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-RNO-9020259 https://reactome.org/PathwayBrowser/#/R-RNO-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-SSC-9020259 https://reactome.org/PathwayBrowser/#/R-SSC-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Sus scrofa 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-XTR-9020259 https://reactome.org/PathwayBrowser/#/R-XTR-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 138601 R-ALL-9024576 4(S)-Hp-17(R)-HDHA [cytosol] R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-BTA-9020251 https://reactome.org/PathwayBrowser/#/R-BTA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Bos taurus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-CFA-9020251 https://reactome.org/PathwayBrowser/#/R-CFA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Canis familiaris 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-DDI-9020251 https://reactome.org/PathwayBrowser/#/R-DDI-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-DRE-9020251 https://reactome.org/PathwayBrowser/#/R-DRE-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Danio rerio 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-GGA-9020251 https://reactome.org/PathwayBrowser/#/R-GGA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Gallus gallus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9020251 https://reactome.org/PathwayBrowser/#/R-HSA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA TAS Homo sapiens 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-MMU-9020251 https://reactome.org/PathwayBrowser/#/R-MMU-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Mus musculus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-RNO-9020251 https://reactome.org/PathwayBrowser/#/R-RNO-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Rattus norvegicus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-SSC-9020251 https://reactome.org/PathwayBrowser/#/R-SSC-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Sus scrofa 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-XTR-9020251 https://reactome.org/PathwayBrowser/#/R-XTR-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Xenopus tropicalis 138602 R-ALL-9024479 7(S)-Hp-17(R)-HDHA [cytosol] R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-BTA-9020278 https://reactome.org/PathwayBrowser/#/R-BTA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Bos taurus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-CFA-9020278 https://reactome.org/PathwayBrowser/#/R-CFA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Canis familiaris 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-DDI-9020278 https://reactome.org/PathwayBrowser/#/R-DDI-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Dictyostelium discoideum 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-DRE-9020278 https://reactome.org/PathwayBrowser/#/R-DRE-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Danio rerio 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-GGA-9020278 https://reactome.org/PathwayBrowser/#/R-GGA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Gallus gallus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-HSA-9020278 https://reactome.org/PathwayBrowser/#/R-HSA-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA TAS Homo sapiens 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-MMU-9020278 https://reactome.org/PathwayBrowser/#/R-MMU-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Mus musculus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-RNO-9020278 https://reactome.org/PathwayBrowser/#/R-RNO-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Rattus norvegicus 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-SSC-9020278 https://reactome.org/PathwayBrowser/#/R-SSC-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Sus scrofa 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138612 R-ALL-9024577 4S(5)-epoxy-17(R)-HDHA [cytosol] R-XTR-9020278 https://reactome.org/PathwayBrowser/#/R-XTR-9020278 ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA IEA Xenopus tropicalis 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-BTA-9020256 https://reactome.org/PathwayBrowser/#/R-BTA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Bos taurus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-CFA-9020256 https://reactome.org/PathwayBrowser/#/R-CFA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Canis familiaris 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-DDI-9020256 https://reactome.org/PathwayBrowser/#/R-DDI-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Dictyostelium discoideum 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-DRE-9020256 https://reactome.org/PathwayBrowser/#/R-DRE-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Danio rerio 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-GGA-9020256 https://reactome.org/PathwayBrowser/#/R-GGA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Gallus gallus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-HSA-9020256 https://reactome.org/PathwayBrowser/#/R-HSA-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA TAS Homo sapiens 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-MMU-9020256 https://reactome.org/PathwayBrowser/#/R-MMU-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Mus musculus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-RNO-9020256 https://reactome.org/PathwayBrowser/#/R-RNO-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Rattus norvegicus 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-SSC-9020256 https://reactome.org/PathwayBrowser/#/R-SSC-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Sus scrofa 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138613 R-ALL-9024602 7S(8)-epoxy-17(R)-HDHA [cytosol] R-XTR-9020256 https://reactome.org/PathwayBrowser/#/R-XTR-9020256 ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA IEA Xenopus tropicalis 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138614 R-ALL-9024584 aspirin-triggered resolvin D2 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 138614 R-ALL-9024598 aspirin-triggered resolvin D2 [cytosol] R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138615 R-ALL-9024591 aspirin-triggered resolvin D3 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138615 R-ALL-9024592 aspirin-triggered resolvin D3 [cytosol] R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138616 R-ALL-9024568 aspirin-triggered resolvin D4 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 138616 R-ALL-9024599 aspirin-triggered resolvin D4 [cytosol] R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 138617 R-ALL-9024639 AT-RvD5 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138617 R-ALL-9024641 aspirin-triggered resolvin D5 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138617 R-ALL-9024639 AT-RvD5 [cytosol] R-HSA-9024630 https://reactome.org/PathwayBrowser/#/R-HSA-9024630 Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 TAS Homo sapiens 138618 R-ALL-9024633 AT-RvD6 [cytosol] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138618 R-ALL-9024646 aspirin-triggered resolvin D6 [extracellular region] R-HSA-9024586 https://reactome.org/PathwayBrowser/#/R-HSA-9024586 AT-RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138618 R-ALL-9024633 AT-RvD6 [cytosol] R-HSA-9024624 https://reactome.org/PathwayBrowser/#/R-HSA-9024624 Hydroperoxy reductase reduces 4(S)-Hp-17(R)-HDHA to AT-RvD6 TAS Homo sapiens 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-BTA-9020264 https://reactome.org/PathwayBrowser/#/R-BTA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Bos taurus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-CFA-9020264 https://reactome.org/PathwayBrowser/#/R-CFA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Canis familiaris 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-DDI-9020264 https://reactome.org/PathwayBrowser/#/R-DDI-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-DRE-9020264 https://reactome.org/PathwayBrowser/#/R-DRE-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Danio rerio 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-GGA-9020264 https://reactome.org/PathwayBrowser/#/R-GGA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Gallus gallus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020264 https://reactome.org/PathwayBrowser/#/R-HSA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA TAS Homo sapiens 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-MMU-9020264 https://reactome.org/PathwayBrowser/#/R-MMU-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Mus musculus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-RNO-9020264 https://reactome.org/PathwayBrowser/#/R-RNO-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-SSC-9020264 https://reactome.org/PathwayBrowser/#/R-SSC-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Sus scrofa 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-XTR-9020264 https://reactome.org/PathwayBrowser/#/R-XTR-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138641 R-ALL-9024797 4(S)-Hp-17(S)-HDHA [cytosol] R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-BTA-9020282 https://reactome.org/PathwayBrowser/#/R-BTA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Bos taurus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-CFA-9020282 https://reactome.org/PathwayBrowser/#/R-CFA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Canis familiaris 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-DDI-9020282 https://reactome.org/PathwayBrowser/#/R-DDI-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-DRE-9020282 https://reactome.org/PathwayBrowser/#/R-DRE-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Danio rerio 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-GGA-9020282 https://reactome.org/PathwayBrowser/#/R-GGA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Gallus gallus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reductase reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-HSA-9020282 https://reactome.org/PathwayBrowser/#/R-HSA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA TAS Homo sapiens 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-MMU-9020282 https://reactome.org/PathwayBrowser/#/R-MMU-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Mus musculus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-RNO-9020282 https://reactome.org/PathwayBrowser/#/R-RNO-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Rattus norvegicus 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-SSC-9020282 https://reactome.org/PathwayBrowser/#/R-SSC-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Sus scrofa 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 138642 R-ALL-9024765 7(S)-Hp-17(S)-HDHA [cytosol] R-XTR-9020282 https://reactome.org/PathwayBrowser/#/R-XTR-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Xenopus tropicalis 138643 R-ALL-9024803 resolvin D6 [cytosol] R-HSA-9020249 https://reactome.org/PathwayBrowser/#/R-HSA-9020249 Hydroperoxy reductase reduces 4(S)-Hp-17(S)-HDHA to RvD6 TAS Homo sapiens 138643 R-ALL-9024803 resolvin D6 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138643 R-ALL-9024780 resolvin D6 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-BTA-9020255 https://reactome.org/PathwayBrowser/#/R-BTA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Bos taurus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-BTA-9026911 https://reactome.org/PathwayBrowser/#/R-BTA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Bos taurus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-CFA-9020255 https://reactome.org/PathwayBrowser/#/R-CFA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Canis familiaris 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-CFA-9026911 https://reactome.org/PathwayBrowser/#/R-CFA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Canis familiaris 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DDI-9020255 https://reactome.org/PathwayBrowser/#/R-DDI-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Dictyostelium discoideum 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DDI-9026911 https://reactome.org/PathwayBrowser/#/R-DDI-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Dictyostelium discoideum 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DRE-9020255 https://reactome.org/PathwayBrowser/#/R-DRE-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Danio rerio 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-GGA-9020255 https://reactome.org/PathwayBrowser/#/R-GGA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Gallus gallus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-GGA-9026911 https://reactome.org/PathwayBrowser/#/R-GGA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Gallus gallus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-HSA-9020255 https://reactome.org/PathwayBrowser/#/R-HSA-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA TAS Homo sapiens 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-HSA-9026911 https://reactome.org/PathwayBrowser/#/R-HSA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 TAS Homo sapiens 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-MMU-9020255 https://reactome.org/PathwayBrowser/#/R-MMU-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Mus musculus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-MMU-9026911 https://reactome.org/PathwayBrowser/#/R-MMU-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Mus musculus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-RNO-9020255 https://reactome.org/PathwayBrowser/#/R-RNO-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Rattus norvegicus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-RNO-9026911 https://reactome.org/PathwayBrowser/#/R-RNO-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Rattus norvegicus 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-SSC-9020255 https://reactome.org/PathwayBrowser/#/R-SSC-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Sus scrofa 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-SSC-9026911 https://reactome.org/PathwayBrowser/#/R-SSC-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Sus scrofa 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-XTR-9020255 https://reactome.org/PathwayBrowser/#/R-XTR-9020255 ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA IEA Xenopus tropicalis 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 138646 R-ALL-9024768 7S(8)-epoxy-17(S)-HDHA [cytosol] R-XTR-9026911 https://reactome.org/PathwayBrowser/#/R-XTR-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Xenopus tropicalis 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-BTA-9020277 https://reactome.org/PathwayBrowser/#/R-BTA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Bos taurus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-CFA-9020277 https://reactome.org/PathwayBrowser/#/R-CFA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Canis familiaris 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-DDI-9020277 https://reactome.org/PathwayBrowser/#/R-DDI-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Dictyostelium discoideum 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-DRE-9020277 https://reactome.org/PathwayBrowser/#/R-DRE-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Danio rerio 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-GGA-9020277 https://reactome.org/PathwayBrowser/#/R-GGA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Gallus gallus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-HSA-9020277 https://reactome.org/PathwayBrowser/#/R-HSA-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA TAS Homo sapiens 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-MMU-9020277 https://reactome.org/PathwayBrowser/#/R-MMU-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Mus musculus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-RNO-9020277 https://reactome.org/PathwayBrowser/#/R-RNO-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Rattus norvegicus 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-SSC-9020277 https://reactome.org/PathwayBrowser/#/R-SSC-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Sus scrofa 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138647 R-ALL-9024781 4S(5)-epoxy-17(S)-HDHA [cytosol] R-XTR-9020277 https://reactome.org/PathwayBrowser/#/R-XTR-9020277 ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA IEA Xenopus tropicalis 138648 R-ALL-9024807 resolvin D3 [cytosol] R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138648 R-ALL-9024807 resolvin D3 [cytosol] R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138648 R-ALL-9024807 resolvin D3 [cytosol] R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138648 R-ALL-9024807 resolvin D3 [cytosol] R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138648 R-ALL-9024807 resolvin D3 [cytosol] R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138648 R-ALL-9024807 resolvin D3 [cytosol] R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138648 R-ALL-9024807 resolvin D3 [cytosol] R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138648 R-ALL-9024807 resolvin D3 [cytosol] R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138648 R-ALL-9024807 resolvin D3 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138648 R-ALL-9024819 resolvin D3 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138648 R-ALL-9024807 resolvin D3 [cytosol] R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138648 R-ALL-9024807 resolvin D3 [cytosol] R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138648 R-ALL-9024807 resolvin D3 [cytosol] R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138648 R-ALL-9024807 resolvin D3 [cytosol] R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138648 R-ALL-9024807 resolvin D3 [cytosol] R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138648 R-ALL-9024807 resolvin D3 [cytosol] R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138649 R-ALL-9024794 resolvin D4 [cytosol] R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 138649 R-ALL-9024794 resolvin D4 [cytosol] R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 138649 R-ALL-9024794 resolvin D4 [cytosol] R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 138649 R-ALL-9024794 resolvin D4 [cytosol] R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 138649 R-ALL-9024794 resolvin D4 [cytosol] R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 138649 R-ALL-9024794 resolvin D4 [cytosol] R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 138649 R-ALL-9024794 resolvin D4 [cytosol] R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 138649 R-ALL-9024794 resolvin D4 [cytosol] R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 138649 R-ALL-9024794 resolvin D4 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138649 R-ALL-9024792 resolvin D4 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 138649 R-ALL-9024794 resolvin D4 [cytosol] R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 138649 R-ALL-9024794 resolvin D4 [cytosol] R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 138649 R-ALL-9024794 resolvin D4 [cytosol] R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 138649 R-ALL-9024794 resolvin D4 [cytosol] R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 138649 R-ALL-9024794 resolvin D4 [cytosol] R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 138649 R-ALL-9024794 resolvin D4 [cytosol] R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 138653 R-ALL-9024883 PDX [cytosol] R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 138653 R-ALL-9024883 PDX [cytosol] R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 138653 R-ALL-9024883 PDX [cytosol] R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 138653 R-ALL-9024883 PDX [cytosol] R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 138653 R-ALL-9024883 PDX [cytosol] R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 138653 R-ALL-9024883 PDX [cytosol] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 138653 R-ALL-9031814 PDX [extracellular region] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 138653 R-ALL-9024883 PDX [cytosol] R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 138653 R-ALL-9024883 PDX [cytosol] R-RNO-9024872 https://reactome.org/PathwayBrowser/#/R-RNO-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Rattus norvegicus 138653 R-ALL-9024883 PDX [cytosol] R-SSC-9024872 https://reactome.org/PathwayBrowser/#/R-SSC-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Sus scrofa 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138673 R-ALL-9031895 17(S)-HDPAn-6 [extracellular region] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 138673 R-ALL-9025154 (4Z,7Z,10Z,13Z,15E,17S)-17-hydroxydocosapentaenoic acid [cytosol] R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138674 R-ALL-9031903 10(S),17(S)-diHDPAn-6 [extracellular region] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-RNO-9025152 https://reactome.org/PathwayBrowser/#/R-RNO-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Rattus norvegicus 138674 R-ALL-9025147 10(S),17(S)-dihydroxy-omega 6-docosapentaenoic acid [cytosol] R-SSC-9025152 https://reactome.org/PathwayBrowser/#/R-SSC-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Sus scrofa 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-BTA-70342 https://reactome.org/PathwayBrowser/#/R-BTA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Bos taurus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-CEL-70342 https://reactome.org/PathwayBrowser/#/R-CEL-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Caenorhabditis elegans 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-CFA-70342 https://reactome.org/PathwayBrowser/#/R-CFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Canis familiaris 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-DDI-70342 https://reactome.org/PathwayBrowser/#/R-DDI-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Dictyostelium discoideum 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-DME-70342 https://reactome.org/PathwayBrowser/#/R-DME-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Drosophila melanogaster 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-DRE-70342 https://reactome.org/PathwayBrowser/#/R-DRE-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Danio rerio 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-GGA-70342 https://reactome.org/PathwayBrowser/#/R-GGA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Gallus gallus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-HSA-70342 https://reactome.org/PathwayBrowser/#/R-HSA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP TAS Homo sapiens 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-MMU-70342 https://reactome.org/PathwayBrowser/#/R-MMU-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Mus musculus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-PFA-70342 https://reactome.org/PathwayBrowser/#/R-PFA-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Plasmodium falciparum 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-RNO-70342 https://reactome.org/PathwayBrowser/#/R-RNO-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Rattus norvegicus 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-SSC-70342 https://reactome.org/PathwayBrowser/#/R-SSC-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Sus scrofa 138881 R-ALL-9832976 beta-D-Fru 1-P [cytosol] R-XTR-70342 https://reactome.org/PathwayBrowser/#/R-XTR-70342 ALDOB tetramer cleaves Fru-1-P to GA and DHAP IEA Xenopus tropicalis 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-433592 https://reactome.org/PathwayBrowser/#/R-GGA-433592 sphinganine + stearyl-CoA => dihydroceramide + CoASH IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 139048 R-ALL-428126 DHCE [endoplasmic reticulum membrane] R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 139051 R-ALL-9025544 phytoceramide [endoplasmic reticulum membrane] R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 139150 R-ALL-9840885 BMP [multivesicular body, internal vesicle membrane] R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 139350 R-ALL-9033790 Type 2 chain [Golgi lumen] R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-BTA-9033949 https://reactome.org/PathwayBrowser/#/R-BTA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Bos taurus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-CEL-9033949 https://reactome.org/PathwayBrowser/#/R-CEL-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Caenorhabditis elegans 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-HSA-9033949 https://reactome.org/PathwayBrowser/#/R-HSA-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC TAS Homo sapiens 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-MMU-9033949 https://reactome.org/PathwayBrowser/#/R-MMU-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Mus musculus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-RNO-9033949 https://reactome.org/PathwayBrowser/#/R-RNO-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Rattus norvegicus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-SSC-9033949 https://reactome.org/PathwayBrowser/#/R-SSC-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Sus scrofa 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-XTR-9033949 https://reactome.org/PathwayBrowser/#/R-XTR-9033949 FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC IEA Xenopus tropicalis 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 139351 R-ALL-9033793 H antigen-RBC [Golgi lumen] R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-BTA-9033959 https://reactome.org/PathwayBrowser/#/R-BTA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Bos taurus 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-CFA-9033959 https://reactome.org/PathwayBrowser/#/R-CFA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Canis familiaris 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-DRE-9033959 https://reactome.org/PathwayBrowser/#/R-DRE-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Danio rerio 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-HSA-9033959 https://reactome.org/PathwayBrowser/#/R-HSA-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC TAS Homo sapiens 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-MMU-9033959 https://reactome.org/PathwayBrowser/#/R-MMU-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Mus musculus 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-RNO-9033959 https://reactome.org/PathwayBrowser/#/R-RNO-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Rattus norvegicus 139352 R-ALL-9033802 A antigen-RBC [Golgi lumen] R-XTR-9033959 https://reactome.org/PathwayBrowser/#/R-XTR-9033959 ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC IEA Xenopus tropicalis 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-BTA-9033961 https://reactome.org/PathwayBrowser/#/R-BTA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Bos taurus 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-CFA-9033961 https://reactome.org/PathwayBrowser/#/R-CFA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Canis familiaris 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-DRE-9033961 https://reactome.org/PathwayBrowser/#/R-DRE-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Danio rerio 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-HSA-9033961 https://reactome.org/PathwayBrowser/#/R-HSA-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC TAS Homo sapiens 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-MMU-9033961 https://reactome.org/PathwayBrowser/#/R-MMU-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Mus musculus 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-RNO-9033961 https://reactome.org/PathwayBrowser/#/R-RNO-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Rattus norvegicus 139353 R-ALL-9033798 B antigen-RBC [Golgi lumen] R-XTR-9033961 https://reactome.org/PathwayBrowser/#/R-XTR-9033961 ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC IEA Xenopus tropicalis 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-BTA-9603986 https://reactome.org/PathwayBrowser/#/R-BTA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Bos taurus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CEL-9603986 https://reactome.org/PathwayBrowser/#/R-CEL-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Caenorhabditis elegans 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CFA-9603986 https://reactome.org/PathwayBrowser/#/R-CFA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Canis familiaris 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-DDI-9603986 https://reactome.org/PathwayBrowser/#/R-DDI-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Dictyostelium discoideum 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-DME-9603986 https://reactome.org/PathwayBrowser/#/R-DME-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Drosophila melanogaster 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-HSA-9603986 https://reactome.org/PathwayBrowser/#/R-HSA-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA TAS Homo sapiens 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-SSC-9603986 https://reactome.org/PathwayBrowser/#/R-SSC-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Sus scrofa 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-XTR-9603986 https://reactome.org/PathwayBrowser/#/R-XTR-9603986 FUT3 transfers Fuc to Type 1 chains to form LeA IEA Xenopus tropicalis 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 140162 R-ALL-9036984 Type 1 chain [Golgi lumen] R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-BTA-9036987 https://reactome.org/PathwayBrowser/#/R-BTA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Bos taurus 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-CEL-9036987 https://reactome.org/PathwayBrowser/#/R-CEL-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Caenorhabditis elegans 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-CFA-9036987 https://reactome.org/PathwayBrowser/#/R-CFA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Canis familiaris 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-HSA-9036987 https://reactome.org/PathwayBrowser/#/R-HSA-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec TAS Homo sapiens 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-HSA-9037612 https://reactome.org/PathwayBrowser/#/R-HSA-9037612 H antigen-sec translocates from Golgi lumen to extracellular region TAS Homo sapiens 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-HSA-9037612 https://reactome.org/PathwayBrowser/#/R-HSA-9037612 H antigen-sec translocates from Golgi lumen to extracellular region TAS Homo sapiens 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-MMU-9036987 https://reactome.org/PathwayBrowser/#/R-MMU-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Mus musculus 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-RNO-9036987 https://reactome.org/PathwayBrowser/#/R-RNO-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Rattus norvegicus 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-SSC-9036987 https://reactome.org/PathwayBrowser/#/R-SSC-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Sus scrofa 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 140180 R-ALL-9034101 H antigen-sec [extracellular region] R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 140180 R-ALL-9037036 H antigen-sec [Golgi lumen] R-XTR-9036987 https://reactome.org/PathwayBrowser/#/R-XTR-9036987 FUT2 transfers Fuc to Type 1 chains to form H antigen-sec IEA Xenopus tropicalis 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-BTA-9034042 https://reactome.org/PathwayBrowser/#/R-BTA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Bos taurus 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-CFA-9034042 https://reactome.org/PathwayBrowser/#/R-CFA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Canis familiaris 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-DRE-9034042 https://reactome.org/PathwayBrowser/#/R-DRE-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Danio rerio 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-HSA-9034042 https://reactome.org/PathwayBrowser/#/R-HSA-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec TAS Homo sapiens 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-MMU-9034042 https://reactome.org/PathwayBrowser/#/R-MMU-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Mus musculus 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-RNO-9034042 https://reactome.org/PathwayBrowser/#/R-RNO-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Rattus norvegicus 140186 R-ALL-9037066 A antigen-sec [extracellular region] R-XTR-9034042 https://reactome.org/PathwayBrowser/#/R-XTR-9034042 sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec IEA Xenopus tropicalis 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-BTA-9034053 https://reactome.org/PathwayBrowser/#/R-BTA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Bos taurus 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-CFA-9034053 https://reactome.org/PathwayBrowser/#/R-CFA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Canis familiaris 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-DRE-9034053 https://reactome.org/PathwayBrowser/#/R-DRE-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Danio rerio 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-HSA-9034053 https://reactome.org/PathwayBrowser/#/R-HSA-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen TAS Homo sapiens 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-MMU-9034053 https://reactome.org/PathwayBrowser/#/R-MMU-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Mus musculus 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-RNO-9034053 https://reactome.org/PathwayBrowser/#/R-RNO-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Rattus norvegicus 140187 R-ALL-9037067 B antigen-sec [extracellular region] R-XTR-9034053 https://reactome.org/PathwayBrowser/#/R-XTR-9034053 sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen IEA Xenopus tropicalis 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-RNO-9024997 https://reactome.org/PathwayBrowser/#/R-RNO-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Rattus norvegicus 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-SSC-9024997 https://reactome.org/PathwayBrowser/#/R-SSC-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Sus scrofa 140196 R-ALL-9024989 7(S),14(S)-diHp-DHA [cytosol] R-XTR-9024997 https://reactome.org/PathwayBrowser/#/R-XTR-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Xenopus tropicalis 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140208 R-ALL-9031798 AT-(N)PD1 [extracellular region] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 140208 R-ALL-9024879 AT-(N)PD1 [cytosol] R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 140235 R-ALL-9026307 13,14(S)-epoxy-DPAn-3 [cytosol] R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 140236 R-ALL-9027537 13-oxo-DHA [cytosol] R-HSA-9027531 https://reactome.org/PathwayBrowser/#/R-HSA-9027531 Dehydrogenase dehydrogenates 13-HDHA to 13-oxo-DHA TAS Homo sapiens 140236 R-ALL-9027537 13-oxo-DHA [cytosol] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140236 R-ALL-9032324 13-oxo-DHA [extracellular region] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140237 R-ALL-9027602 13-oxo-DPAn-3 [cytosol] R-HSA-9027598 https://reactome.org/PathwayBrowser/#/R-HSA-9027598 Dehydrogenase dehydrogenates 13(R)-HDPAn-3 to 13-oxo-DPAn-3 TAS Homo sapiens 140237 R-ALL-9027602 13-oxo-DPAn-3 [cytosol] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140237 R-ALL-9032317 13-oxo-DPAn-3 [extracellular region] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 140251 R-ALL-9031883 14(S)-HDPAn-6 [extracellular region] R-HSA-9031884 https://reactome.org/PathwayBrowser/#/R-HSA-9031884 DPAn-6 SPMs translocate from cytosol to extracellular region TAS Homo sapiens 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-RNO-9025957 https://reactome.org/PathwayBrowser/#/R-RNO-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Rattus norvegicus 140251 R-ALL-9025960 14(S)-HDPAn-6 [cytosol] R-SSC-9025957 https://reactome.org/PathwayBrowser/#/R-SSC-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Sus scrofa 140260 R-ALL-9027622 17-HDHA [cytosol] R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 140260 R-ALL-9027622 17-HDHA [cytosol] R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 140260 R-ALL-9027622 17-HDHA [cytosol] R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 140260 R-ALL-9027622 17-HDHA [cytosol] R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 140260 R-ALL-9027622 17-HDHA [cytosol] R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 140260 R-ALL-9027622 17-HDHA [cytosol] R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 140260 R-ALL-9027622 17-HDHA [cytosol] R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 140260 R-ALL-9027622 17-HDHA [cytosol] R-RNO-9027627 https://reactome.org/PathwayBrowser/#/R-RNO-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Rattus norvegicus 140260 R-ALL-9027622 17-HDHA [cytosol] R-SSC-9027627 https://reactome.org/PathwayBrowser/#/R-SSC-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Sus scrofa 140260 R-ALL-9027622 17-HDHA [cytosol] R-XTR-9027627 https://reactome.org/PathwayBrowser/#/R-XTR-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Xenopus tropicalis 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-BTA-9024983 https://reactome.org/PathwayBrowser/#/R-BTA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Bos taurus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-BTA-9026007 https://reactome.org/PathwayBrowser/#/R-BTA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Bos taurus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-CFA-9024983 https://reactome.org/PathwayBrowser/#/R-CFA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Canis familiaris 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-CFA-9026007 https://reactome.org/PathwayBrowser/#/R-CFA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Canis familiaris 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DDI-9024983 https://reactome.org/PathwayBrowser/#/R-DDI-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Dictyostelium discoideum 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DDI-9026007 https://reactome.org/PathwayBrowser/#/R-DDI-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Dictyostelium discoideum 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DRE-9024983 https://reactome.org/PathwayBrowser/#/R-DRE-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Danio rerio 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-DRE-9026007 https://reactome.org/PathwayBrowser/#/R-DRE-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Danio rerio 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-HSA-9024983 https://reactome.org/PathwayBrowser/#/R-HSA-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA TAS Homo sapiens 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-HSA-9026007 https://reactome.org/PathwayBrowser/#/R-HSA-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 TAS Homo sapiens 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-HSA-9027033 https://reactome.org/PathwayBrowser/#/R-HSA-9027033 Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA TAS Homo sapiens 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-MMU-9024983 https://reactome.org/PathwayBrowser/#/R-MMU-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Mus musculus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-MMU-9026007 https://reactome.org/PathwayBrowser/#/R-MMU-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Mus musculus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-RNO-9020274 https://reactome.org/PathwayBrowser/#/R-RNO-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Rattus norvegicus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-RNO-9024983 https://reactome.org/PathwayBrowser/#/R-RNO-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Rattus norvegicus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-RNO-9024997 https://reactome.org/PathwayBrowser/#/R-RNO-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Rattus norvegicus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-RNO-9026007 https://reactome.org/PathwayBrowser/#/R-RNO-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Rattus norvegicus 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-SSC-9020274 https://reactome.org/PathwayBrowser/#/R-SSC-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Sus scrofa 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-SSC-9024983 https://reactome.org/PathwayBrowser/#/R-SSC-9024983 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA IEA Sus scrofa 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-SSC-9024997 https://reactome.org/PathwayBrowser/#/R-SSC-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Sus scrofa 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-SSC-9026007 https://reactome.org/PathwayBrowser/#/R-SSC-9026007 ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 IEA Sus scrofa 140279 R-ALL-9025012 14(S)-Hp-DHA [cytosol] R-XTR-9024997 https://reactome.org/PathwayBrowser/#/R-XTR-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Xenopus tropicalis 140283 R-ALL-9028207 15d-PGJ3 [cytosol] R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 140283 R-ALL-9028207 15d-PGJ3 [cytosol] R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140283 R-ALL-9032313 15d-PGJ3 [extracellular region] R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140285 R-ALL-9028230 PGJ3 [cytosol] R-HSA-9028263 https://reactome.org/PathwayBrowser/#/R-HSA-9028263 PGJ3 isomerises to δ12-PGJ3 TAS Homo sapiens 140285 R-ALL-9028230 PGJ3 [cytosol] R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 140288 R-ALL-9028201 δ12-PGJ3 [cytosol] R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 140288 R-ALL-9028201 δ12-PGJ3 [cytosol] R-HSA-9028263 https://reactome.org/PathwayBrowser/#/R-HSA-9028263 PGJ3 isomerises to δ12-PGJ3 TAS Homo sapiens 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-RNO-9026005 https://reactome.org/PathwayBrowser/#/R-RNO-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Rattus norvegicus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-RNO-9026006 https://reactome.org/PathwayBrowser/#/R-RNO-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Rattus norvegicus 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-SSC-9026005 https://reactome.org/PathwayBrowser/#/R-SSC-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Sus scrofa 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-SSC-9026006 https://reactome.org/PathwayBrowser/#/R-SSC-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Sus scrofa 140289 R-ALL-9026293 14(S)-Hp-DPAn-3 [cytosol] R-XTR-9026005 https://reactome.org/PathwayBrowser/#/R-XTR-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Xenopus tropicalis 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 140290 R-ALL-9026046 16(S),17(S)-epoxy-DPAn-3 [cytosol] R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-BTA-9025999 https://reactome.org/PathwayBrowser/#/R-BTA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Bos taurus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-BTA-9026003 https://reactome.org/PathwayBrowser/#/R-BTA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Bos taurus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-CFA-9025999 https://reactome.org/PathwayBrowser/#/R-CFA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Canis familiaris 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-CFA-9026003 https://reactome.org/PathwayBrowser/#/R-CFA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Canis familiaris 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DDI-9025999 https://reactome.org/PathwayBrowser/#/R-DDI-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Dictyostelium discoideum 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DDI-9026003 https://reactome.org/PathwayBrowser/#/R-DDI-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DRE-9025999 https://reactome.org/PathwayBrowser/#/R-DRE-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Danio rerio 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-DRE-9026003 https://reactome.org/PathwayBrowser/#/R-DRE-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Danio rerio 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-GGA-9025999 https://reactome.org/PathwayBrowser/#/R-GGA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Gallus gallus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-HSA-9025999 https://reactome.org/PathwayBrowser/#/R-HSA-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 TAS Homo sapiens 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-HSA-9026003 https://reactome.org/PathwayBrowser/#/R-HSA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 TAS Homo sapiens 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-MMU-9025999 https://reactome.org/PathwayBrowser/#/R-MMU-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Mus musculus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-MMU-9026003 https://reactome.org/PathwayBrowser/#/R-MMU-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Mus musculus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-RNO-9025996 https://reactome.org/PathwayBrowser/#/R-RNO-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Rattus norvegicus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-RNO-9025999 https://reactome.org/PathwayBrowser/#/R-RNO-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Rattus norvegicus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-RNO-9026003 https://reactome.org/PathwayBrowser/#/R-RNO-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Rattus norvegicus 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-SSC-9025996 https://reactome.org/PathwayBrowser/#/R-SSC-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Sus scrofa 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-SSC-9025999 https://reactome.org/PathwayBrowser/#/R-SSC-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Sus scrofa 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-SSC-9026003 https://reactome.org/PathwayBrowser/#/R-SSC-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Sus scrofa 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-XTR-9025996 https://reactome.org/PathwayBrowser/#/R-XTR-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Xenopus tropicalis 140291 R-ALL-9026047 17(S)-Hp-DPAn-3 [cytosol] R-XTR-9025999 https://reactome.org/PathwayBrowser/#/R-XTR-9025999 ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 IEA Xenopus tropicalis 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 140293 R-ALL-9026050 7,8-epoxy,17-HDPAn-3 [cytosol] R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 140296 R-ALL-9614942 quinaprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 140296 R-ALL-9614942 quinaprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 140296 R-ALL-9614942 quinaprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 140296 R-ALL-9614942 quinaprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 140296 R-ALL-9614942 quinaprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 140296 R-ALL-9614942 quinaprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 140296 R-ALL-9614942 quinaprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 140296 R-ALL-9614942 quinaprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 140296 R-ALL-9614942 quinaprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 140296 R-ALL-9614942 quinaprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 140296 R-ALL-9614942 quinaprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 140296 R-ALL-9614942 quinaprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 140296 R-ALL-9614942 quinaprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 140296 R-ALL-9614942 quinaprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 140296 R-ALL-9619017 quinaprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-BTA-9024881 https://reactome.org/PathwayBrowser/#/R-BTA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Bos taurus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-CFA-9024881 https://reactome.org/PathwayBrowser/#/R-CFA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Canis familiaris 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-DDI-9024881 https://reactome.org/PathwayBrowser/#/R-DDI-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Dictyostelium discoideum 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-DRE-9024881 https://reactome.org/PathwayBrowser/#/R-DRE-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Danio rerio 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-HSA-9024881 https://reactome.org/PathwayBrowser/#/R-HSA-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA TAS Homo sapiens 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-MMU-9024881 https://reactome.org/PathwayBrowser/#/R-MMU-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Mus musculus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-RNO-9024881 https://reactome.org/PathwayBrowser/#/R-RNO-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Rattus norvegicus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-SSC-9024881 https://reactome.org/PathwayBrowser/#/R-SSC-9024881 ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA IEA Sus scrofa 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 140313 R-ALL-9024873 16S,17S-epoxy-DHA [cytosol] R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 140316 R-ALL-9027626 17-oxo-DHA [cytosol] R-HSA-9027562 https://reactome.org/PathwayBrowser/#/R-HSA-9027562 Dehydrogenase dehydrogenates 17-HDHA to 17-oxo-DHA TAS Homo sapiens 140316 R-ALL-9027626 17-oxo-DHA [cytosol] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140316 R-ALL-9032326 17-oxo-DHA [extracellular region] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140333 R-ALL-9027601 17-oxo-DPAn-3 [cytosol] R-HSA-9027600 https://reactome.org/PathwayBrowser/#/R-HSA-9027600 Dehydrogenase dehydrogenates 17-HDPAn-3 to 17-oxo-DPAn-3 TAS Homo sapiens 140333 R-ALL-9027601 17-oxo-DPAn-3 [cytosol] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140333 R-ALL-9032314 17-oxo-DPAn-3 [extracellular region] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140337 R-ALL-9028202 5-oxo-EPA [cytosol] R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 140337 R-ALL-9028202 5-oxo-EPA [cytosol] R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140337 R-ALL-9032328 5-oxo-EPA [extracellular region] R-HSA-9032327 https://reactome.org/PathwayBrowser/#/R-HSA-9032327 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region TAS Homo sapiens 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-BTA-9020262 https://reactome.org/PathwayBrowser/#/R-BTA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Bos taurus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-CFA-9020262 https://reactome.org/PathwayBrowser/#/R-CFA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Canis familiaris 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-DDI-9020262 https://reactome.org/PathwayBrowser/#/R-DDI-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Dictyostelium discoideum 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-DRE-9020262 https://reactome.org/PathwayBrowser/#/R-DRE-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Danio rerio 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-HSA-9020262 https://reactome.org/PathwayBrowser/#/R-HSA-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA TAS Homo sapiens 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-MMU-9020262 https://reactome.org/PathwayBrowser/#/R-MMU-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Mus musculus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-RNO-9020262 https://reactome.org/PathwayBrowser/#/R-RNO-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Rattus norvegicus 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-SSC-9020262 https://reactome.org/PathwayBrowser/#/R-SSC-9020262 ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA IEA Sus scrofa 140346 R-ALL-9024893 17R(16)-epoxy-DHA [cytosol] R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140348 R-ALL-9037773 22-OH-(N)PD1 [extracellular region] R-HSA-9031807 https://reactome.org/PathwayBrowser/#/R-HSA-9031807 Protectins translocate from cytosol to extracellular region TAS Homo sapiens 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 140348 R-ALL-9037755 22-OH-(N)PD1 [cytosol] R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 140349 R-ALL-9026919 7(S),17(S)-diHp-DHA [cytosol] R-HSA-9026917 https://reactome.org/PathwayBrowser/#/R-HSA-9026917 Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA TAS Homo sapiens 140349 R-ALL-9026919 7(S),17(S)-diHp-DHA [cytosol] R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 140350 R-ALL-9025005 7-epi-MaR1 [cytosol] R-HSA-9025007 https://reactome.org/PathwayBrowser/#/R-HSA-9025007 Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 TAS Homo sapiens 140350 R-ALL-9025005 7-epi-MaR1 [cytosol] R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 140350 R-ALL-9025005 7-epi-MaR1 [cytosol] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 140350 R-ALL-9031808 7-epi-MaR1 [extracellular region] R-HSA-9031802 https://reactome.org/PathwayBrowser/#/R-HSA-9031802 Maresins translocate from cytosol to extracellular region TAS Homo sapiens 140352 R-ALL-9024795 resolvin D5 [cytosol] R-HSA-9020260 https://reactome.org/PathwayBrowser/#/R-HSA-9020260 Hydroperoxy reductase reduces 7(S)-Hp-17(S)-HDHA to RvD5 TAS Homo sapiens 140352 R-ALL-9024795 resolvin D5 [cytosol] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 140352 R-ALL-9024805 resolvin D5 [extracellular region] R-HSA-9024785 https://reactome.org/PathwayBrowser/#/R-HSA-9024785 RvD1-6 translocate from cytosol to extracellular region TAS Homo sapiens 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-HSA-1855220 https://reactome.org/PathwayBrowser/#/R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol TAS Homo sapiens 140372 R-ALL-2023951 3,5-(PP)2-IP4 [nucleoplasm] R-HSA-1855220 https://reactome.org/PathwayBrowser/#/R-HSA-1855220 (PP)2-IP4 transports from the nucleus to the cytosol TAS Homo sapiens 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140372 R-ALL-1629766 3,5-(PP)2-IP4 [cytosol] R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140373 R-ALL-9028274 7-HDHA [cytosol] R-BTA-9027624 https://reactome.org/PathwayBrowser/#/R-BTA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Bos taurus 140373 R-ALL-9028274 7-HDHA [cytosol] R-CFA-9027624 https://reactome.org/PathwayBrowser/#/R-CFA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Canis familiaris 140373 R-ALL-9028274 7-HDHA [cytosol] R-DDI-9027624 https://reactome.org/PathwayBrowser/#/R-DDI-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Dictyostelium discoideum 140373 R-ALL-9028274 7-HDHA [cytosol] R-DRE-9027624 https://reactome.org/PathwayBrowser/#/R-DRE-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Danio rerio 140373 R-ALL-9028274 7-HDHA [cytosol] R-GGA-9027624 https://reactome.org/PathwayBrowser/#/R-GGA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Gallus gallus 140373 R-ALL-9028274 7-HDHA [cytosol] R-HSA-9027624 https://reactome.org/PathwayBrowser/#/R-HSA-9027624 ALOX5 oxidises DHA to 7-HDHA TAS Homo sapiens 140373 R-ALL-9028274 7-HDHA [cytosol] R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 140373 R-ALL-9028274 7-HDHA [cytosol] R-MMU-9027624 https://reactome.org/PathwayBrowser/#/R-MMU-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Mus musculus 140373 R-ALL-9028274 7-HDHA [cytosol] R-RNO-9027624 https://reactome.org/PathwayBrowser/#/R-RNO-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Rattus norvegicus 140373 R-ALL-9028274 7-HDHA [cytosol] R-SSC-9027624 https://reactome.org/PathwayBrowser/#/R-SSC-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Sus scrofa 140373 R-ALL-9028274 7-HDHA [cytosol] R-XTR-9027624 https://reactome.org/PathwayBrowser/#/R-XTR-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Xenopus tropicalis 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-HSA-1855212 https://reactome.org/PathwayBrowser/#/R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus TAS Homo sapiens 140374 R-ALL-2023914 3-PP-IP5 [nucleoplasm] R-HSA-1855212 https://reactome.org/PathwayBrowser/#/R-HSA-1855212 1/3-PP-IP5 transports from the cytosol to the nucleus TAS Homo sapiens 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140374 R-ALL-1629761 3-PP-IP5 [cytosol] R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-BTA-9027633 https://reactome.org/PathwayBrowser/#/R-BTA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Bos taurus 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-CFA-9027633 https://reactome.org/PathwayBrowser/#/R-CFA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Canis familiaris 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-DDI-9027633 https://reactome.org/PathwayBrowser/#/R-DDI-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Dictyostelium discoideum 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-DRE-9027633 https://reactome.org/PathwayBrowser/#/R-DRE-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Danio rerio 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-GGA-9027633 https://reactome.org/PathwayBrowser/#/R-GGA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Gallus gallus 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-HSA-9027633 https://reactome.org/PathwayBrowser/#/R-HSA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 TAS Homo sapiens 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-MMU-9027633 https://reactome.org/PathwayBrowser/#/R-MMU-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Mus musculus 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-RNO-9027633 https://reactome.org/PathwayBrowser/#/R-RNO-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Rattus norvegicus 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-SSC-9027633 https://reactome.org/PathwayBrowser/#/R-SSC-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Sus scrofa 140375 R-ALL-9028240 7-HDPAn-3 [cytosol] R-XTR-9027633 https://reactome.org/PathwayBrowser/#/R-XTR-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Xenopus tropicalis 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-BTA-9025995 https://reactome.org/PathwayBrowser/#/R-BTA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Bos taurus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-CFA-9025995 https://reactome.org/PathwayBrowser/#/R-CFA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Canis familiaris 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-DDI-9025995 https://reactome.org/PathwayBrowser/#/R-DDI-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Dictyostelium discoideum 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-DRE-9025995 https://reactome.org/PathwayBrowser/#/R-DRE-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Danio rerio 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-GGA-9025995 https://reactome.org/PathwayBrowser/#/R-GGA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Gallus gallus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-HSA-9025995 https://reactome.org/PathwayBrowser/#/R-HSA-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 TAS Homo sapiens 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-MMU-9025995 https://reactome.org/PathwayBrowser/#/R-MMU-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Mus musculus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-RNO-9025995 https://reactome.org/PathwayBrowser/#/R-RNO-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Rattus norvegicus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-RNO-9025996 https://reactome.org/PathwayBrowser/#/R-RNO-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Rattus norvegicus 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-SSC-9025995 https://reactome.org/PathwayBrowser/#/R-SSC-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Sus scrofa 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-SSC-9025996 https://reactome.org/PathwayBrowser/#/R-SSC-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Sus scrofa 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-XTR-9025995 https://reactome.org/PathwayBrowser/#/R-XTR-9025995 ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 IEA Xenopus tropicalis 140381 R-ALL-9026034 7,17-diHp-DPAn-3 [cytosol] R-XTR-9025996 https://reactome.org/PathwayBrowser/#/R-XTR-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Xenopus tropicalis 140382 R-ALL-9028265 7-oxo-DHA [cytosol] R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 140382 R-ALL-9028265 7-oxo-DHA [cytosol] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140382 R-ALL-9032321 7-oxo-DHA [extracellular region] R-HSA-9032315 https://reactome.org/PathwayBrowser/#/R-HSA-9032315 oxo-DHAs translocate from cytosol to extracellular region TAS Homo sapiens 140386 R-ALL-9028200 7-oxo-DPAn-3 [cytosol] R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 140386 R-ALL-9028200 7-oxo-DPAn-3 [cytosol] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140386 R-ALL-9032316 7-oxo-DPAn-3 [extracellular region] R-HSA-9032323 https://reactome.org/PathwayBrowser/#/R-HSA-9032323 oxo-DPAn-3s translocate from cytosol to extracellular region TAS Homo sapiens 140387 R-ALL-9026322 MaR2n-3 DPA [cytosol] R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140387 R-ALL-9026322 MaR2n-3 DPA [cytosol] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140387 R-ALL-9031882 MaR2n-3 DPA [extracellular region] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140389 R-ALL-9026319 MaR1n-3 DPA [cytosol] R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 140389 R-ALL-9026319 MaR1n-3 DPA [cytosol] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140389 R-ALL-9031898 MaR1n-3 DPA [extracellular region] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140393 R-ALL-9031886 MaR3n-3 DPA [extracellular region] R-HSA-9031894 https://reactome.org/PathwayBrowser/#/R-HSA-9031894 DPAn-3 maresins translocate from cytosol to extracellular region TAS Homo sapiens 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-RNO-9026005 https://reactome.org/PathwayBrowser/#/R-RNO-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Rattus norvegicus 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-SSC-9026005 https://reactome.org/PathwayBrowser/#/R-SSC-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Sus scrofa 140393 R-ALL-9026311 MaR3n-3 DPA [cytosol] R-XTR-9026005 https://reactome.org/PathwayBrowser/#/R-XTR-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Xenopus tropicalis 140394 R-ALL-9026903 PCTR1 [cytosol] R-HSA-9026901 https://reactome.org/PathwayBrowser/#/R-HSA-9026901 GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 TAS Homo sapiens 140394 R-ALL-9026903 PCTR1 [cytosol] R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 140394 R-ALL-9026903 PCTR1 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140394 R-ALL-9031848 PCTR1 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140397 R-ALL-9026921 PCTR2 [cytosol] R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 140397 R-ALL-9026921 PCTR2 [cytosol] R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 140397 R-ALL-9026921 PCTR2 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140397 R-ALL-9031849 PCTR2 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140401 R-ALL-9026906 PCTR3 [cytosol] R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 140401 R-ALL-9026906 PCTR3 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140401 R-ALL-9031857 PCTR3 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140405 R-ALL-9026024 PD1n-3DPA [cytosol] R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140405 R-ALL-9026024 PD1n-3DPA [cytosol] R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140405 R-ALL-9031893 PD1n-3DPA [extracellular region] R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140406 R-ALL-9026055 PD2n-3DPA [cytosol] R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 140406 R-ALL-9026055 PD2n-3DPA [cytosol] R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140406 R-ALL-9031901 PD2n-3DPA [extracellular region] R-HSA-9031896 https://reactome.org/PathwayBrowser/#/R-HSA-9031896 PD1n-3, PD2n-3 translocate from cytosol to extracellular region TAS Homo sapiens 140409 R-ALL-9026915 RCTR1 [cytosol] R-BTA-9026911 https://reactome.org/PathwayBrowser/#/R-BTA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Bos taurus 140409 R-ALL-9026915 RCTR1 [cytosol] R-CFA-9026911 https://reactome.org/PathwayBrowser/#/R-CFA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Canis familiaris 140409 R-ALL-9026915 RCTR1 [cytosol] R-DDI-9026911 https://reactome.org/PathwayBrowser/#/R-DDI-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Dictyostelium discoideum 140409 R-ALL-9026915 RCTR1 [cytosol] R-GGA-9026911 https://reactome.org/PathwayBrowser/#/R-GGA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Gallus gallus 140409 R-ALL-9026915 RCTR1 [cytosol] R-HSA-9026911 https://reactome.org/PathwayBrowser/#/R-HSA-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 TAS Homo sapiens 140409 R-ALL-9026915 RCTR1 [cytosol] R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 140409 R-ALL-9026915 RCTR1 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140409 R-ALL-9031858 RCTR1 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140409 R-ALL-9026915 RCTR1 [cytosol] R-MMU-9026911 https://reactome.org/PathwayBrowser/#/R-MMU-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Mus musculus 140409 R-ALL-9026915 RCTR1 [cytosol] R-RNO-9026911 https://reactome.org/PathwayBrowser/#/R-RNO-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Rattus norvegicus 140409 R-ALL-9026915 RCTR1 [cytosol] R-SSC-9026911 https://reactome.org/PathwayBrowser/#/R-SSC-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Sus scrofa 140409 R-ALL-9026915 RCTR1 [cytosol] R-XTR-9026911 https://reactome.org/PathwayBrowser/#/R-XTR-9026911 LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 IEA Xenopus tropicalis 140412 R-ALL-9026922 RCTR2 [cytosol] R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 140412 R-ALL-9026922 RCTR2 [cytosol] R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 140412 R-ALL-9026922 RCTR2 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140412 R-ALL-9031852 RCTR2 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140413 R-ALL-9026914 RCTR3 [cytosol] R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 140413 R-ALL-9026914 RCTR3 [cytosol] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140413 R-ALL-9031847 RCTR3 [extracellular region] R-HSA-9031856 https://reactome.org/PathwayBrowser/#/R-HSA-9031856 Sulfido conjugates translocate from cytosol to extracellular region TAS Homo sapiens 140415 R-ALL-9026288 RvD1n-3DPA [cytosol] R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140415 R-ALL-9026288 RvD1n-3DPA [cytosol] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140415 R-ALL-9031902 RvD1n-3DPA [extracellular region] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140416 R-ALL-9026289 RvD2n-3DPA [cytosol] R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 140416 R-ALL-9026289 RvD2n-3DPA [cytosol] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140416 R-ALL-9031891 RvD2n-3DPA [extracellular region] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140419 R-ALL-9026036 RvD5n-3DPA [cytosol] R-HSA-9026001 https://reactome.org/PathwayBrowser/#/R-HSA-9026001 Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA TAS Homo sapiens 140419 R-ALL-9026036 RvD5n-3DPA [cytosol] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140419 R-ALL-9031888 RvD5n-3DPA [extracellular region] R-HSA-9031881 https://reactome.org/PathwayBrowser/#/R-HSA-9031881 DPAn-3 resolvins translocate from cytosol to extracellular region TAS Homo sapiens 140420 R-ALL-9603671 eribaxaban [extracellular region] R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 140420 R-ALL-9603671 eribaxaban [extracellular region] R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 140420 R-ALL-9603671 eribaxaban [extracellular region] R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 140420 R-ALL-9603671 eribaxaban [extracellular region] R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 140420 R-ALL-9603671 eribaxaban [extracellular region] R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 140420 R-ALL-9603671 eribaxaban [extracellular region] R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 140420 R-ALL-9603671 eribaxaban [extracellular region] R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 140420 R-ALL-9603671 eribaxaban [extracellular region] R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 140420 R-ALL-9603671 eribaxaban [extracellular region] R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 140420 R-ALL-9603671 eribaxaban [extracellular region] R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 140420 R-ALL-9603671 eribaxaban [extracellular region] R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 140420 R-ALL-9603671 eribaxaban [extracellular region] R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 140420 R-ALL-9603671 eribaxaban [extracellular region] R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 140420 R-ALL-9603671 eribaxaban [extracellular region] R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 140420 R-ALL-9603671 eribaxaban [extracellular region] R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 140420 R-ALL-9603671 eribaxaban [extracellular region] R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 140420 R-ALL-9603671 eribaxaban [extracellular region] R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 140421 R-ALL-9038746 betrixaban [extracellular region] R-BTA-140664 https://reactome.org/PathwayBrowser/#/R-BTA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Bos taurus 140421 R-ALL-9038746 betrixaban [extracellular region] R-BTA-140700 https://reactome.org/PathwayBrowser/#/R-BTA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Bos taurus 140421 R-ALL-9038746 betrixaban [extracellular region] R-BTA-9015111 https://reactome.org/PathwayBrowser/#/R-BTA-9015111 Factor Xa inhibitors binds Xa IEA Bos taurus 140421 R-ALL-9038746 betrixaban [extracellular region] R-BTA-9015122 https://reactome.org/PathwayBrowser/#/R-BTA-9015122 Factor Xa inhibitors bind Va:Xa IEA Bos taurus 140421 R-ALL-9038746 betrixaban [extracellular region] R-CFA-140664 https://reactome.org/PathwayBrowser/#/R-CFA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Canis familiaris 140421 R-ALL-9038746 betrixaban [extracellular region] R-CFA-140700 https://reactome.org/PathwayBrowser/#/R-CFA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Canis familiaris 140421 R-ALL-9038746 betrixaban [extracellular region] R-CFA-9015111 https://reactome.org/PathwayBrowser/#/R-CFA-9015111 Factor Xa inhibitors binds Xa IEA Canis familiaris 140421 R-ALL-9038746 betrixaban [extracellular region] R-CFA-9015122 https://reactome.org/PathwayBrowser/#/R-CFA-9015122 Factor Xa inhibitors bind Va:Xa IEA Canis familiaris 140421 R-ALL-9038746 betrixaban [extracellular region] R-DRE-9015111 https://reactome.org/PathwayBrowser/#/R-DRE-9015111 Factor Xa inhibitors binds Xa IEA Danio rerio 140421 R-ALL-9038746 betrixaban [extracellular region] R-DRE-9015122 https://reactome.org/PathwayBrowser/#/R-DRE-9015122 Factor Xa inhibitors bind Va:Xa IEA Danio rerio 140421 R-ALL-9038746 betrixaban [extracellular region] R-GGA-140664 https://reactome.org/PathwayBrowser/#/R-GGA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Gallus gallus 140421 R-ALL-9038746 betrixaban [extracellular region] R-GGA-140700 https://reactome.org/PathwayBrowser/#/R-GGA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Gallus gallus 140421 R-ALL-9038746 betrixaban [extracellular region] R-GGA-9015111 https://reactome.org/PathwayBrowser/#/R-GGA-9015111 Factor Xa inhibitors binds Xa IEA Gallus gallus 140421 R-ALL-9038746 betrixaban [extracellular region] R-GGA-9015122 https://reactome.org/PathwayBrowser/#/R-GGA-9015122 Factor Xa inhibitors bind Va:Xa IEA Gallus gallus 140421 R-ALL-9038746 betrixaban [extracellular region] R-HSA-140664 https://reactome.org/PathwayBrowser/#/R-HSA-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) TAS Homo sapiens 140421 R-ALL-9038746 betrixaban [extracellular region] R-HSA-140700 https://reactome.org/PathwayBrowser/#/R-HSA-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) TAS Homo sapiens 140421 R-ALL-9038746 betrixaban [extracellular region] R-HSA-9015111 https://reactome.org/PathwayBrowser/#/R-HSA-9015111 Factor Xa inhibitors binds Xa TAS Homo sapiens 140421 R-ALL-9038746 betrixaban [extracellular region] R-HSA-9015122 https://reactome.org/PathwayBrowser/#/R-HSA-9015122 Factor Xa inhibitors bind Va:Xa TAS Homo sapiens 140421 R-ALL-9038746 betrixaban [extracellular region] R-MMU-140664 https://reactome.org/PathwayBrowser/#/R-MMU-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Mus musculus 140421 R-ALL-9038746 betrixaban [extracellular region] R-MMU-140700 https://reactome.org/PathwayBrowser/#/R-MMU-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Mus musculus 140421 R-ALL-9038746 betrixaban [extracellular region] R-MMU-9015111 https://reactome.org/PathwayBrowser/#/R-MMU-9015111 Factor Xa inhibitors binds Xa IEA Mus musculus 140421 R-ALL-9038746 betrixaban [extracellular region] R-MMU-9015122 https://reactome.org/PathwayBrowser/#/R-MMU-9015122 Factor Xa inhibitors bind Va:Xa IEA Mus musculus 140421 R-ALL-9038746 betrixaban [extracellular region] R-RNO-140700 https://reactome.org/PathwayBrowser/#/R-RNO-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Rattus norvegicus 140421 R-ALL-9038746 betrixaban [extracellular region] R-RNO-9015111 https://reactome.org/PathwayBrowser/#/R-RNO-9015111 Factor Xa inhibitors binds Xa IEA Rattus norvegicus 140421 R-ALL-9038746 betrixaban [extracellular region] R-SSC-140664 https://reactome.org/PathwayBrowser/#/R-SSC-140664 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) IEA Sus scrofa 140421 R-ALL-9038746 betrixaban [extracellular region] R-SSC-140700 https://reactome.org/PathwayBrowser/#/R-SSC-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Sus scrofa 140421 R-ALL-9038746 betrixaban [extracellular region] R-SSC-9015111 https://reactome.org/PathwayBrowser/#/R-SSC-9015111 Factor Xa inhibitors binds Xa IEA Sus scrofa 140421 R-ALL-9038746 betrixaban [extracellular region] R-SSC-9015122 https://reactome.org/PathwayBrowser/#/R-SSC-9015122 Factor Xa inhibitors bind Va:Xa IEA Sus scrofa 140421 R-ALL-9038746 betrixaban [extracellular region] R-XTR-140700 https://reactome.org/PathwayBrowser/#/R-XTR-140700 prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) IEA Xenopus tropicalis 140421 R-ALL-9038746 betrixaban [extracellular region] R-XTR-9015111 https://reactome.org/PathwayBrowser/#/R-XTR-9015111 Factor Xa inhibitors binds Xa IEA Xenopus tropicalis 140427 R-ALL-9603260 desirudin [extracellular region] R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 140427 R-ALL-9603260 desirudin [extracellular region] R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 140427 R-ALL-9603260 desirudin [extracellular region] R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 140427 R-ALL-9603260 desirudin [extracellular region] R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Bos taurus 140427 R-ALL-9603260 desirudin [extracellular region] R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 140427 R-ALL-9603260 desirudin [extracellular region] R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Canis familiaris 140427 R-ALL-9603260 desirudin [extracellular region] R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 140427 R-ALL-9603260 desirudin [extracellular region] R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 140427 R-ALL-9603260 desirudin [extracellular region] R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 140427 R-ALL-9603260 desirudin [extracellular region] R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 140427 R-ALL-9603260 desirudin [extracellular region] R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Gallus gallus 140427 R-ALL-9603260 desirudin [extracellular region] R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 140427 R-ALL-9603260 desirudin [extracellular region] R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 140427 R-ALL-9603260 desirudin [extracellular region] R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 140427 R-ALL-9603260 desirudin [extracellular region] R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 140427 R-ALL-9603260 desirudin [extracellular region] R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) bind IIa TAS Homo sapiens 140427 R-ALL-9603260 desirudin [extracellular region] R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 140427 R-ALL-9603260 desirudin [extracellular region] R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 140427 R-ALL-9603260 desirudin [extracellular region] R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 140427 R-ALL-9603260 desirudin [extracellular region] R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 140427 R-ALL-9603260 desirudin [extracellular region] R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Mus musculus 140427 R-ALL-9603260 desirudin [extracellular region] R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 140427 R-ALL-9603260 desirudin [extracellular region] R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 140427 R-ALL-9603260 desirudin [extracellular region] R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 140427 R-ALL-9603260 desirudin [extracellular region] R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Rattus norvegicus 140427 R-ALL-9603260 desirudin [extracellular region] R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 140427 R-ALL-9603260 desirudin [extracellular region] R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 140427 R-ALL-9603260 desirudin [extracellular region] R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 140427 R-ALL-9603260 desirudin [extracellular region] R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Sus scrofa 140427 R-ALL-9603260 desirudin [extracellular region] R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 140427 R-ALL-9603260 desirudin [extracellular region] R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 140427 R-ALL-9603260 desirudin [extracellular region] R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Xenopus tropicalis 140472 R-ALL-9603697 DUP-714 [extracellular region] R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-BTA-9015379 https://reactome.org/PathwayBrowser/#/R-BTA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Bos taurus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 140472 R-ALL-9603697 DUP-714 [extracellular region] R-CFA-9015379 https://reactome.org/PathwayBrowser/#/R-CFA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Canis familiaris 140472 R-ALL-9603697 DUP-714 [extracellular region] R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-GGA-9015379 https://reactome.org/PathwayBrowser/#/R-GGA-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Gallus gallus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 140472 R-ALL-9603697 DUP-714 [extracellular region] R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 140472 R-ALL-9603697 DUP-714 [extracellular region] R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 140472 R-ALL-9603697 DUP-714 [extracellular region] R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 140472 R-ALL-9603697 DUP-714 [extracellular region] R-HSA-9015379 https://reactome.org/PathwayBrowser/#/R-HSA-9015379 Factor IIa inhibitors (compounds) binds IIa TAS Homo sapiens 140472 R-ALL-9603697 DUP-714 [extracellular region] R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-MMU-9015379 https://reactome.org/PathwayBrowser/#/R-MMU-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Mus musculus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-RNO-9015379 https://reactome.org/PathwayBrowser/#/R-RNO-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Rattus norvegicus 140472 R-ALL-9603697 DUP-714 [extracellular region] R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 140472 R-ALL-9603697 DUP-714 [extracellular region] R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 140472 R-ALL-9603697 DUP-714 [extracellular region] R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 140472 R-ALL-9603697 DUP-714 [extracellular region] R-SSC-9015379 https://reactome.org/PathwayBrowser/#/R-SSC-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Sus scrofa 140472 R-ALL-9603697 DUP-714 [extracellular region] R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 140472 R-ALL-9603697 DUP-714 [extracellular region] R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 140472 R-ALL-9603697 DUP-714 [extracellular region] R-XTR-9015379 https://reactome.org/PathwayBrowser/#/R-XTR-9015379 Factor IIa inhibitors (compounds) binds IIa IEA Xenopus tropicalis 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000074 https://reactome.org/PathwayBrowser/#/R-BTA-3000074 TCN2 binds RCbl in the circulation IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000103 https://reactome.org/PathwayBrowser/#/R-BTA-3000103 CUBN:AMN binds CBLIF:RCbl IEA Bos taurus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-BTA-3000112 https://reactome.org/PathwayBrowser/#/R-BTA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000112 https://reactome.org/PathwayBrowser/#/R-BTA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000120 https://reactome.org/PathwayBrowser/#/R-BTA-3000120 CBLIF binds RCbl IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000122 https://reactome.org/PathwayBrowser/#/R-BTA-3000122 CD320 binds extracellular TCN2:RCbl IEA Bos taurus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-BTA-3000137 https://reactome.org/PathwayBrowser/#/R-BTA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3000137 https://reactome.org/PathwayBrowser/#/R-BTA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759394 RCbl [cytosol] R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 140785 R-ALL-9759394 RCbl [cytosol] R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3132753 https://reactome.org/PathwayBrowser/#/R-BTA-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-3132759 https://reactome.org/PathwayBrowser/#/R-BTA-3132759 TCN1 binds RCbl IEA Bos taurus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 140785 R-ALL-9759394 RCbl [cytosol] R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-BTA-9759202 https://reactome.org/PathwayBrowser/#/R-BTA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-9759202 https://reactome.org/PathwayBrowser/#/R-BTA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Bos taurus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 140785 R-ALL-9759394 RCbl [cytosol] R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 140785 R-ALL-9759382 RCbl [extracellular region] R-BTA-9759209 https://reactome.org/PathwayBrowser/#/R-BTA-9759209 LRP2 binds extracellular TCN2:RCbl IEA Bos taurus 140785 R-ALL-9759394 RCbl [cytosol] R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 140785 R-ALL-9759394 RCbl [cytosol] R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 140785 R-ALL-9759382 RCbl [extracellular region] R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3000074 https://reactome.org/PathwayBrowser/#/R-CFA-3000074 TCN2 binds RCbl in the circulation IEA Canis familiaris 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-CFA-3000112 https://reactome.org/PathwayBrowser/#/R-CFA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3000112 https://reactome.org/PathwayBrowser/#/R-CFA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3000120 https://reactome.org/PathwayBrowser/#/R-CFA-3000120 CBLIF binds RCbl IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3000122 https://reactome.org/PathwayBrowser/#/R-CFA-3000122 CD320 binds extracellular TCN2:RCbl IEA Canis familiaris 140785 R-ALL-9759394 RCbl [cytosol] R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 140785 R-ALL-9759394 RCbl [cytosol] R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3132753 https://reactome.org/PathwayBrowser/#/R-CFA-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-3132759 https://reactome.org/PathwayBrowser/#/R-CFA-3132759 TCN1 binds RCbl IEA Canis familiaris 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 140785 R-ALL-9759394 RCbl [cytosol] R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-CFA-9759202 https://reactome.org/PathwayBrowser/#/R-CFA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-9759202 https://reactome.org/PathwayBrowser/#/R-CFA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Canis familiaris 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 140785 R-ALL-9759394 RCbl [cytosol] R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 140785 R-ALL-9759382 RCbl [extracellular region] R-CFA-9759209 https://reactome.org/PathwayBrowser/#/R-CFA-9759209 LRP2 binds extracellular TCN2:RCbl IEA Canis familiaris 140785 R-ALL-9759394 RCbl [cytosol] R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 140785 R-ALL-9759394 RCbl [cytosol] R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 140785 R-ALL-9759382 RCbl [extracellular region] R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 140785 R-ALL-9759394 RCbl [cytosol] R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 140785 R-ALL-9759394 RCbl [cytosol] R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000074 https://reactome.org/PathwayBrowser/#/R-DME-3000074 TCN2 binds RCbl in the circulation IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000103 https://reactome.org/PathwayBrowser/#/R-DME-3000103 CUBN:AMN binds CBLIF:RCbl IEA Drosophila melanogaster 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-DME-3000112 https://reactome.org/PathwayBrowser/#/R-DME-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000112 https://reactome.org/PathwayBrowser/#/R-DME-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000120 https://reactome.org/PathwayBrowser/#/R-DME-3000120 CBLIF binds RCbl IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000122 https://reactome.org/PathwayBrowser/#/R-DME-3000122 CD320 binds extracellular TCN2:RCbl IEA Drosophila melanogaster 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-DME-3000137 https://reactome.org/PathwayBrowser/#/R-DME-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3000137 https://reactome.org/PathwayBrowser/#/R-DME-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Drosophila melanogaster 140785 R-ALL-9759394 RCbl [cytosol] R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 140785 R-ALL-9759382 RCbl [extracellular region] R-DME-3132759 https://reactome.org/PathwayBrowser/#/R-DME-3132759 TCN1 binds RCbl IEA Drosophila melanogaster 140785 R-ALL-9759394 RCbl [cytosol] R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 140785 R-ALL-9759382 RCbl [extracellular region] R-GGA-3000074 https://reactome.org/PathwayBrowser/#/R-GGA-3000074 TCN2 binds RCbl in the circulation IEA Gallus gallus 140785 R-ALL-9759394 RCbl [cytosol] R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 140785 R-ALL-9759394 RCbl [cytosol] R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 140785 R-ALL-9759382 RCbl [extracellular region] R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 140785 R-ALL-9759394 RCbl [cytosol] R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 140785 R-ALL-9759394 RCbl [cytosol] R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000074 https://reactome.org/PathwayBrowser/#/R-HSA-3000074 TCN2 binds RCbl in the circulation TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000103 https://reactome.org/PathwayBrowser/#/R-HSA-3000103 CUBN:AMN binds CBLIF:RCbl TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-3000112 https://reactome.org/PathwayBrowser/#/R-HSA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000112 https://reactome.org/PathwayBrowser/#/R-HSA-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000120 https://reactome.org/PathwayBrowser/#/R-HSA-3000120 CBLIF binds RCbl TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000122 https://reactome.org/PathwayBrowser/#/R-HSA-3000122 CD320 binds extracellular TCN2:RCbl TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-3000137 https://reactome.org/PathwayBrowser/#/R-HSA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3000137 https://reactome.org/PathwayBrowser/#/R-HSA-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-3000243 https://reactome.org/PathwayBrowser/#/R-HSA-3000243 Unknown lysosomal protease degrades CBLIF:RCbl to release Cbl TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-3000263 https://reactome.org/PathwayBrowser/#/R-HSA-3000263 TCN2:RCbl is degraded to release RCbl TAS Homo sapiens 140785 R-ALL-9759394 RCbl [cytosol] R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 140785 R-ALL-9759394 RCbl [cytosol] R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3132753 https://reactome.org/PathwayBrowser/#/R-HSA-3132753 Pancreatic proteases degrade TCN1:RCbl TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3132759 https://reactome.org/PathwayBrowser/#/R-HSA-3132759 TCN1 binds RCbl TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3296462 https://reactome.org/PathwayBrowser/#/R-HSA-3296462 Defective CUBN does not transport GIF:Cbl TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-3296477 https://reactome.org/PathwayBrowser/#/R-HSA-3296477 Defective AMN does not transport GIF:Cbl TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 140785 R-ALL-9759394 RCbl [cytosol] R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-9759202 https://reactome.org/PathwayBrowser/#/R-HSA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-9759202 https://reactome.org/PathwayBrowser/#/R-HSA-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome TAS Homo sapiens 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 140785 R-ALL-9759394 RCbl [cytosol] R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-HSA-9759209 https://reactome.org/PathwayBrowser/#/R-HSA-9759209 LRP2 binds extracellular TCN2:RCbl TAS Homo sapiens 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-3000074 https://reactome.org/PathwayBrowser/#/R-MMU-3000074 TCN2 binds RCbl in the circulation IEA Mus musculus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-MMU-3000112 https://reactome.org/PathwayBrowser/#/R-MMU-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-3000112 https://reactome.org/PathwayBrowser/#/R-MMU-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-3000120 https://reactome.org/PathwayBrowser/#/R-MMU-3000120 CBLIF binds RCbl IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-3000122 https://reactome.org/PathwayBrowser/#/R-MMU-3000122 CD320 binds extracellular TCN2:RCbl IEA Mus musculus 140785 R-ALL-9759394 RCbl [cytosol] R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 140785 R-ALL-9759394 RCbl [cytosol] R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 140785 R-ALL-9759394 RCbl [cytosol] R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-MMU-9759202 https://reactome.org/PathwayBrowser/#/R-MMU-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-9759202 https://reactome.org/PathwayBrowser/#/R-MMU-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Mus musculus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 140785 R-ALL-9759394 RCbl [cytosol] R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-MMU-9759209 https://reactome.org/PathwayBrowser/#/R-MMU-9759209 LRP2 binds extracellular TCN2:RCbl IEA Mus musculus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000074 https://reactome.org/PathwayBrowser/#/R-RNO-3000074 TCN2 binds RCbl in the circulation IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000103 https://reactome.org/PathwayBrowser/#/R-RNO-3000103 CUBN:AMN binds CBLIF:RCbl IEA Rattus norvegicus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-RNO-3000112 https://reactome.org/PathwayBrowser/#/R-RNO-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000112 https://reactome.org/PathwayBrowser/#/R-RNO-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000120 https://reactome.org/PathwayBrowser/#/R-RNO-3000120 CBLIF binds RCbl IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000122 https://reactome.org/PathwayBrowser/#/R-RNO-3000122 CD320 binds extracellular TCN2:RCbl IEA Rattus norvegicus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-RNO-3000137 https://reactome.org/PathwayBrowser/#/R-RNO-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3000137 https://reactome.org/PathwayBrowser/#/R-RNO-3000137 CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759394 RCbl [cytosol] R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 140785 R-ALL-9759394 RCbl [cytosol] R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-RNO-9759202 https://reactome.org/PathwayBrowser/#/R-RNO-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-9759202 https://reactome.org/PathwayBrowser/#/R-RNO-9759202 LRP2-mediated TCN2:RCbl uptake and delivery to lysosome IEA Rattus norvegicus 140785 R-ALL-9759382 RCbl [extracellular region] R-RNO-9759209 https://reactome.org/PathwayBrowser/#/R-RNO-9759209 LRP2 binds extracellular TCN2:RCbl IEA Rattus norvegicus 140785 R-ALL-9759394 RCbl [cytosol] R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 140785 R-ALL-9759382 RCbl [extracellular region] R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 140785 R-ALL-9759394 RCbl [cytosol] R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 140785 R-ALL-9759382 RCbl [extracellular region] R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3000074 https://reactome.org/PathwayBrowser/#/R-SSC-3000074 TCN2 binds RCbl in the circulation IEA Sus scrofa 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-SSC-3000112 https://reactome.org/PathwayBrowser/#/R-SSC-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3000112 https://reactome.org/PathwayBrowser/#/R-SSC-3000112 CD320-mediated TCN2:RCbl uptake and delivery to lysosome IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3000120 https://reactome.org/PathwayBrowser/#/R-SSC-3000120 CBLIF binds RCbl IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3000122 https://reactome.org/PathwayBrowser/#/R-SSC-3000122 CD320 binds extracellular TCN2:RCbl IEA Sus scrofa 140785 R-ALL-9759394 RCbl [cytosol] R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 140785 R-ALL-9759394 RCbl [cytosol] R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3132753 https://reactome.org/PathwayBrowser/#/R-SSC-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-SSC-3132759 https://reactome.org/PathwayBrowser/#/R-SSC-3132759 TCN1 binds RCbl IEA Sus scrofa 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 140785 R-ALL-9759394 RCbl [cytosol] R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 140785 R-ALL-9759390 RCbl [lysosomal lumen] R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 140785 R-ALL-9759394 RCbl [cytosol] R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 140785 R-ALL-9759382 RCbl [extracellular region] R-XTR-3000074 https://reactome.org/PathwayBrowser/#/R-XTR-3000074 TCN2 binds RCbl in the circulation IEA Xenopus tropicalis 140785 R-ALL-9759382 RCbl [extracellular region] R-XTR-3000120 https://reactome.org/PathwayBrowser/#/R-XTR-3000120 CBLIF binds RCbl IEA Xenopus tropicalis 140785 R-ALL-9759394 RCbl [cytosol] R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 140785 R-ALL-9759394 RCbl [cytosol] R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 140785 R-ALL-9759382 RCbl [extracellular region] R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 140785 R-ALL-9759382 RCbl [extracellular region] R-XTR-3132753 https://reactome.org/PathwayBrowser/#/R-XTR-3132753 Pancreatic proteases degrade TCN1:RCbl IEA Xenopus tropicalis 140785 R-ALL-9759382 RCbl [extracellular region] R-XTR-3132759 https://reactome.org/PathwayBrowser/#/R-XTR-3132759 TCN1 binds RCbl IEA Xenopus tropicalis 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-BTA-9603989 https://reactome.org/PathwayBrowser/#/R-BTA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Bos taurus 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-CEL-9603989 https://reactome.org/PathwayBrowser/#/R-CEL-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Caenorhabditis elegans 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-CFA-9603989 https://reactome.org/PathwayBrowser/#/R-CFA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Canis familiaris 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-DME-9603989 https://reactome.org/PathwayBrowser/#/R-DME-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Drosophila melanogaster 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-DRE-9603989 https://reactome.org/PathwayBrowser/#/R-DRE-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Danio rerio 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-GGA-9603989 https://reactome.org/PathwayBrowser/#/R-GGA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Gallus gallus 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-HSA-9603989 https://reactome.org/PathwayBrowser/#/R-HSA-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain TAS Homo sapiens 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-MMU-9603989 https://reactome.org/PathwayBrowser/#/R-MMU-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Mus musculus 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-RNO-9603989 https://reactome.org/PathwayBrowser/#/R-RNO-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Rattus norvegicus 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-SSC-9603989 https://reactome.org/PathwayBrowser/#/R-SSC-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Sus scrofa 140876 R-ALL-9604808 GlcNAc-β1,3-Gal-R [Golgi lumen] R-XTR-9603989 https://reactome.org/PathwayBrowser/#/R-XTR-9603989 B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain IEA Xenopus tropicalis 140911 R-ALL-9605593 LeX [Golgi lumen] R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 140911 R-ALL-9605593 LeX [Golgi lumen] R-BTA-9603984 https://reactome.org/PathwayBrowser/#/R-BTA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Bos taurus 140911 R-ALL-9605593 LeX [Golgi lumen] R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 140911 R-ALL-9605593 LeX [Golgi lumen] R-CEL-9603984 https://reactome.org/PathwayBrowser/#/R-CEL-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Caenorhabditis elegans 140911 R-ALL-9605593 LeX [Golgi lumen] R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 140911 R-ALL-9605593 LeX [Golgi lumen] R-CFA-9603984 https://reactome.org/PathwayBrowser/#/R-CFA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Canis familiaris 140911 R-ALL-9605593 LeX [Golgi lumen] R-DDI-9603984 https://reactome.org/PathwayBrowser/#/R-DDI-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Dictyostelium discoideum 140911 R-ALL-9605593 LeX [Golgi lumen] R-DME-9603984 https://reactome.org/PathwayBrowser/#/R-DME-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Drosophila melanogaster 140911 R-ALL-9605593 LeX [Golgi lumen] R-DRE-9603984 https://reactome.org/PathwayBrowser/#/R-DRE-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Danio rerio 140911 R-ALL-9605593 LeX [Golgi lumen] R-GGA-9603984 https://reactome.org/PathwayBrowser/#/R-GGA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Gallus gallus 140911 R-ALL-9605593 LeX [Golgi lumen] R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 140911 R-ALL-9605593 LeX [Golgi lumen] R-HSA-9603984 https://reactome.org/PathwayBrowser/#/R-HSA-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX TAS Homo sapiens 140911 R-ALL-9605593 LeX [Golgi lumen] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140911 R-ALL-9606399 LeX [extracellular region] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140911 R-ALL-9605593 LeX [Golgi lumen] R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 140911 R-ALL-9605593 LeX [Golgi lumen] R-MMU-9603984 https://reactome.org/PathwayBrowser/#/R-MMU-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Mus musculus 140911 R-ALL-9605593 LeX [Golgi lumen] R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 140911 R-ALL-9605593 LeX [Golgi lumen] R-RNO-9603984 https://reactome.org/PathwayBrowser/#/R-RNO-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Rattus norvegicus 140911 R-ALL-9605593 LeX [Golgi lumen] R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 140911 R-ALL-9605593 LeX [Golgi lumen] R-SSC-9603984 https://reactome.org/PathwayBrowser/#/R-SSC-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Sus scrofa 140911 R-ALL-9605593 LeX [Golgi lumen] R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 140911 R-ALL-9605593 LeX [Golgi lumen] R-XTR-9603984 https://reactome.org/PathwayBrowser/#/R-XTR-9603984 FUT4,5,9 transfer Fuc to Type 2 chains to form LeX IEA Xenopus tropicalis 140912 R-ALL-9605586 LeY [Golgi lumen] R-BTA-9603983 https://reactome.org/PathwayBrowser/#/R-BTA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Bos taurus 140912 R-ALL-9605586 LeY [Golgi lumen] R-CEL-9603983 https://reactome.org/PathwayBrowser/#/R-CEL-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Caenorhabditis elegans 140912 R-ALL-9605586 LeY [Golgi lumen] R-CFA-9603983 https://reactome.org/PathwayBrowser/#/R-CFA-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Canis familiaris 140912 R-ALL-9605586 LeY [Golgi lumen] R-HSA-9603983 https://reactome.org/PathwayBrowser/#/R-HSA-9603983 FUT2 transfers Fuc to LeX to form LeY TAS Homo sapiens 140912 R-ALL-9605586 LeY [Golgi lumen] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140912 R-ALL-9606398 LeY [extracellular region] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140912 R-ALL-9605586 LeY [Golgi lumen] R-MMU-9603983 https://reactome.org/PathwayBrowser/#/R-MMU-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Mus musculus 140912 R-ALL-9605586 LeY [Golgi lumen] R-RNO-9603983 https://reactome.org/PathwayBrowser/#/R-RNO-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Rattus norvegicus 140912 R-ALL-9605586 LeY [Golgi lumen] R-SSC-9603983 https://reactome.org/PathwayBrowser/#/R-SSC-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Sus scrofa 140912 R-ALL-9605586 LeY [Golgi lumen] R-XTR-9603983 https://reactome.org/PathwayBrowser/#/R-XTR-9603983 FUT2 transfers Fuc to LeX to form LeY IEA Xenopus tropicalis 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140915 R-ALL-9606391 dsLeA [extracellular region] R-HSA-9606392 https://reactome.org/PathwayBrowser/#/R-HSA-9606392 Lewis antigens translocate from Golgi lumen to extracellular region TAS Homo sapiens 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 140915 R-ALL-9605651 dsLeA [Golgi lumen] R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-BTA-9603987 https://reactome.org/PathwayBrowser/#/R-BTA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Bos taurus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-BTA-9605609 https://reactome.org/PathwayBrowser/#/R-BTA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Bos taurus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-CEL-9605609 https://reactome.org/PathwayBrowser/#/R-CEL-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Caenorhabditis elegans 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-CFA-9603987 https://reactome.org/PathwayBrowser/#/R-CFA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Canis familiaris 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-CFA-9605609 https://reactome.org/PathwayBrowser/#/R-CFA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Canis familiaris 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-DDI-9605609 https://reactome.org/PathwayBrowser/#/R-DDI-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Dictyostelium discoideum 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-DME-9605609 https://reactome.org/PathwayBrowser/#/R-DME-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Drosophila melanogaster 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-GGA-9603987 https://reactome.org/PathwayBrowser/#/R-GGA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Gallus gallus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-HSA-9603987 https://reactome.org/PathwayBrowser/#/R-HSA-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG TAS Homo sapiens 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-HSA-9605609 https://reactome.org/PathwayBrowser/#/R-HSA-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA TAS Homo sapiens 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-MMU-9603987 https://reactome.org/PathwayBrowser/#/R-MMU-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Mus musculus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-RNO-9603987 https://reactome.org/PathwayBrowser/#/R-RNO-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Rattus norvegicus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-SSC-9603987 https://reactome.org/PathwayBrowser/#/R-SSC-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Sus scrofa 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-SSC-9605609 https://reactome.org/PathwayBrowser/#/R-SSC-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Sus scrofa 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-XTR-9603987 https://reactome.org/PathwayBrowser/#/R-XTR-9603987 ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG IEA Xenopus tropicalis 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 140917 R-ALL-9605595 Type 1 MSGG [Golgi lumen] R-XTR-9605609 https://reactome.org/PathwayBrowser/#/R-XTR-9605609 FUT3 transfers Fuc to Type 1 MSGG to form sLeA IEA Xenopus tropicalis 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-BTA-9605600 https://reactome.org/PathwayBrowser/#/R-BTA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Bos taurus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-BTA-9605682 https://reactome.org/PathwayBrowser/#/R-BTA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Bos taurus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-BTA-9605700 https://reactome.org/PathwayBrowser/#/R-BTA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Bos taurus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-CEL-9605682 https://reactome.org/PathwayBrowser/#/R-CEL-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Caenorhabditis elegans 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-CFA-9605600 https://reactome.org/PathwayBrowser/#/R-CFA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Canis familiaris 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-CFA-9605682 https://reactome.org/PathwayBrowser/#/R-CFA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Canis familiaris 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-CFA-9605700 https://reactome.org/PathwayBrowser/#/R-CFA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Canis familiaris 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-DDI-9605682 https://reactome.org/PathwayBrowser/#/R-DDI-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Dictyostelium discoideum 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-DME-9605682 https://reactome.org/PathwayBrowser/#/R-DME-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Drosophila melanogaster 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-DRE-9605600 https://reactome.org/PathwayBrowser/#/R-DRE-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Danio rerio 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-DRE-9605682 https://reactome.org/PathwayBrowser/#/R-DRE-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Danio rerio 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-GGA-9605600 https://reactome.org/PathwayBrowser/#/R-GGA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Gallus gallus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-GGA-9605682 https://reactome.org/PathwayBrowser/#/R-GGA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Gallus gallus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-HSA-9605600 https://reactome.org/PathwayBrowser/#/R-HSA-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG TAS Homo sapiens 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-HSA-9605682 https://reactome.org/PathwayBrowser/#/R-HSA-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX TAS Homo sapiens 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-HSA-9605700 https://reactome.org/PathwayBrowser/#/R-HSA-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda TAS Homo sapiens 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-MMU-9605600 https://reactome.org/PathwayBrowser/#/R-MMU-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Mus musculus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-MMU-9605682 https://reactome.org/PathwayBrowser/#/R-MMU-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Mus musculus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-MMU-9605700 https://reactome.org/PathwayBrowser/#/R-MMU-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Mus musculus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-RNO-9605600 https://reactome.org/PathwayBrowser/#/R-RNO-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Rattus norvegicus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-RNO-9605682 https://reactome.org/PathwayBrowser/#/R-RNO-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Rattus norvegicus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-RNO-9605700 https://reactome.org/PathwayBrowser/#/R-RNO-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Rattus norvegicus 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-SSC-9605600 https://reactome.org/PathwayBrowser/#/R-SSC-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Sus scrofa 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-SSC-9605682 https://reactome.org/PathwayBrowser/#/R-SSC-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Sus scrofa 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-SSC-9605700 https://reactome.org/PathwayBrowser/#/R-SSC-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Sus scrofa 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-XTR-9605600 https://reactome.org/PathwayBrowser/#/R-XTR-9605600 ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG IEA Xenopus tropicalis 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-XTR-9605682 https://reactome.org/PathwayBrowser/#/R-XTR-9605682 FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX IEA Xenopus tropicalis 140918 R-ALL-9605685 Type 2 MSGG [Golgi lumen] R-XTR-9605700 https://reactome.org/PathwayBrowser/#/R-XTR-9605700 B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda IEA Xenopus tropicalis 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-BTA-9603991 https://reactome.org/PathwayBrowser/#/R-BTA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Bos taurus 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-BTA-9605644 https://reactome.org/PathwayBrowser/#/R-BTA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Bos taurus 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-CEL-9605644 https://reactome.org/PathwayBrowser/#/R-CEL-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Caenorhabditis elegans 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-CFA-9603991 https://reactome.org/PathwayBrowser/#/R-CFA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Canis familiaris 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-CFA-9605644 https://reactome.org/PathwayBrowser/#/R-CFA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Canis familiaris 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-DDI-9605644 https://reactome.org/PathwayBrowser/#/R-DDI-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Dictyostelium discoideum 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-DME-9605644 https://reactome.org/PathwayBrowser/#/R-DME-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Drosophila melanogaster 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-GGA-9603991 https://reactome.org/PathwayBrowser/#/R-GGA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Gallus gallus 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-HSA-9603991 https://reactome.org/PathwayBrowser/#/R-HSA-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG TAS Homo sapiens 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-HSA-9605644 https://reactome.org/PathwayBrowser/#/R-HSA-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA TAS Homo sapiens 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-MMU-9603991 https://reactome.org/PathwayBrowser/#/R-MMU-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Mus musculus 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-RNO-9603991 https://reactome.org/PathwayBrowser/#/R-RNO-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Rattus norvegicus 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-SSC-9603991 https://reactome.org/PathwayBrowser/#/R-SSC-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Sus scrofa 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-SSC-9605644 https://reactome.org/PathwayBrowser/#/R-SSC-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Sus scrofa 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-XTR-9603991 https://reactome.org/PathwayBrowser/#/R-XTR-9603991 ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG IEA Xenopus tropicalis 140919 R-ALL-9605649 Type 1 DSGG [Golgi lumen] R-XTR-9605644 https://reactome.org/PathwayBrowser/#/R-XTR-9605644 FUT3 transfers Fuc to Type 1 DSGG to form dsLeA IEA Xenopus tropicalis 141346 R-ALL-9611841 solabegron [extracellular region] R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 141346 R-ALL-9611841 solabegron [extracellular region] R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 141346 R-ALL-9611841 solabegron [extracellular region] R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 141346 R-ALL-9611841 solabegron [extracellular region] R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 141346 R-ALL-9611841 solabegron [extracellular region] R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 141346 R-ALL-9611841 solabegron [extracellular region] R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 141346 R-ALL-9611841 solabegron [extracellular region] R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 141346 R-ALL-9611841 solabegron [extracellular region] R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 141346 R-ALL-9611841 solabegron [extracellular region] R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 141346 R-ALL-9611841 solabegron [extracellular region] R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 141346 R-ALL-9611841 solabegron [extracellular region] R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 141346 R-ALL-9611841 solabegron [extracellular region] R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 141346 R-ALL-9611841 solabegron [extracellular region] R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 141346 R-ALL-9611841 solabegron [extracellular region] R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 141346 R-ALL-9611841 solabegron [extracellular region] R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 141346 R-ALL-9611841 solabegron [extracellular region] R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 141499 R-ALL-31503 HTMLYS [cytosol] R-BTA-71249 https://reactome.org/PathwayBrowser/#/R-BTA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Bos taurus 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 141499 R-ALL-31503 HTMLYS [cytosol] R-CEL-71249 https://reactome.org/PathwayBrowser/#/R-CEL-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Caenorhabditis elegans 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 141499 R-ALL-31503 HTMLYS [cytosol] R-CFA-71249 https://reactome.org/PathwayBrowser/#/R-CFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Canis familiaris 141499 R-ALL-31503 HTMLYS [cytosol] R-DDI-71249 https://reactome.org/PathwayBrowser/#/R-DDI-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Dictyostelium discoideum 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 141499 R-ALL-31503 HTMLYS [cytosol] R-DME-71249 https://reactome.org/PathwayBrowser/#/R-DME-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Drosophila melanogaster 141499 R-ALL-31503 HTMLYS [cytosol] R-DRE-71249 https://reactome.org/PathwayBrowser/#/R-DRE-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Danio rerio 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 141499 R-ALL-31503 HTMLYS [cytosol] R-GGA-71249 https://reactome.org/PathwayBrowser/#/R-GGA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Gallus gallus 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 141499 R-ALL-31503 HTMLYS [cytosol] R-HSA-71249 https://reactome.org/PathwayBrowser/#/R-HSA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly TAS Homo sapiens 141499 R-ALL-31503 HTMLYS [cytosol] R-HSA-8949413 https://reactome.org/PathwayBrowser/#/R-HSA-8949413 HTMLYS translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-HSA-8949413 https://reactome.org/PathwayBrowser/#/R-HSA-8949413 HTMLYS translocates from the mitochondrial matrix to the cytosol TAS Homo sapiens 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 141499 R-ALL-31503 HTMLYS [cytosol] R-MMU-71249 https://reactome.org/PathwayBrowser/#/R-MMU-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Mus musculus 141499 R-ALL-31503 HTMLYS [cytosol] R-PFA-71249 https://reactome.org/PathwayBrowser/#/R-PFA-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Plasmodium falciparum 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus norvegicus 141499 R-ALL-31503 HTMLYS [cytosol] R-RNO-71249 https://reactome.org/PathwayBrowser/#/R-RNO-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Rattus norvegicus 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-SSC-71241 https://reactome.org/PathwayBrowser/#/R-SSC-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Sus scrofa 141499 R-ALL-31503 HTMLYS [cytosol] R-SSC-71249 https://reactome.org/PathwayBrowser/#/R-SSC-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Sus scrofa 141499 R-ALL-113546 HTMLYS [mitochondrial matrix] R-XTR-71241 https://reactome.org/PathwayBrowser/#/R-XTR-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Xenopus tropicalis 141499 R-ALL-31503 HTMLYS [cytosol] R-XTR-71249 https://reactome.org/PathwayBrowser/#/R-XTR-71249 SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly IEA Xenopus tropicalis 141520 R-ALL-9614914 imidaprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141520 R-ALL-9614914 imidaprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141520 R-ALL-9614914 imidaprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141520 R-ALL-9614914 imidaprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141520 R-ALL-9614914 imidaprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141520 R-ALL-9614914 imidaprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141520 R-ALL-9614914 imidaprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141520 R-ALL-9614914 imidaprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141520 R-ALL-9614914 imidaprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141520 R-ALL-9614914 imidaprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141520 R-ALL-9614914 imidaprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141520 R-ALL-9614914 imidaprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141520 R-ALL-9614914 imidaprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141520 R-ALL-9614914 imidaprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141520 R-ALL-9619026 imidaprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141521 R-ALL-9614937 trandolaprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141521 R-ALL-9619041 trandolaprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141522 R-ALL-9614961 spiraprilat [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-BTA-9614933 https://reactome.org/PathwayBrowser/#/R-BTA-9614933 ACEIs bind ACE IEA Bos taurus 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 141522 R-ALL-9614961 spiraprilat [extracellular region] R-CEL-9614933 https://reactome.org/PathwayBrowser/#/R-CEL-9614933 ACEIs bind ACE IEA Caenorhabditis elegans 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 141522 R-ALL-9614961 spiraprilat [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 141522 R-ALL-9614961 spiraprilat [extracellular region] R-CFA-9614933 https://reactome.org/PathwayBrowser/#/R-CFA-9614933 ACEIs bind ACE IEA Canis familiaris 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 141522 R-ALL-9614961 spiraprilat [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 141522 R-ALL-9614961 spiraprilat [extracellular region] R-DME-9614933 https://reactome.org/PathwayBrowser/#/R-DME-9614933 ACEIs bind ACE IEA Drosophila melanogaster 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 141522 R-ALL-9614961 spiraprilat [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-GGA-9614933 https://reactome.org/PathwayBrowser/#/R-GGA-9614933 ACEIs bind ACE IEA Gallus gallus 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 141522 R-ALL-9614961 spiraprilat [extracellular region] R-HSA-9614933 https://reactome.org/PathwayBrowser/#/R-HSA-9614933 ACEIs bind ACE TAS Homo sapiens 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 141522 R-ALL-9614961 spiraprilat [extracellular region] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-HSA-9619034 https://reactome.org/PathwayBrowser/#/R-HSA-9619034 ACEIs translocate from ER lumen to extracellular region TAS Homo sapiens 141522 R-ALL-9614961 spiraprilat [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-MMU-9614933 https://reactome.org/PathwayBrowser/#/R-MMU-9614933 ACEIs bind ACE IEA Mus musculus 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-RNO-9614933 https://reactome.org/PathwayBrowser/#/R-RNO-9614933 ACEIs bind ACE IEA Rattus norvegicus 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 141522 R-ALL-9614961 spiraprilat [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 141522 R-ALL-9614961 spiraprilat [extracellular region] R-SSC-9614933 https://reactome.org/PathwayBrowser/#/R-SSC-9614933 ACEIs bind ACE IEA Sus scrofa 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 141522 R-ALL-9614961 spiraprilat [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 141522 R-ALL-9614961 spiraprilat [extracellular region] R-XTR-9614933 https://reactome.org/PathwayBrowser/#/R-XTR-9614933 ACEIs bind ACE IEA Xenopus tropicalis 141522 R-ALL-9619049 spiraprilat [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 141552 R-ALL-9615735 forasartan [extracellular region] R-BTA-374173 https://reactome.org/PathwayBrowser/#/R-BTA-374173 AGT(34-41) binds to AGTR1 IEA Bos taurus 141552 R-ALL-9615735 forasartan [extracellular region] R-BTA-9615249 https://reactome.org/PathwayBrowser/#/R-BTA-9615249 ARBs bind AGRT1 IEA Bos taurus 141552 R-ALL-9615735 forasartan [extracellular region] R-CEL-374173 https://reactome.org/PathwayBrowser/#/R-CEL-374173 AGT(34-41) binds to AGTR1 IEA Caenorhabditis elegans 141552 R-ALL-9615735 forasartan [extracellular region] R-CEL-9615249 https://reactome.org/PathwayBrowser/#/R-CEL-9615249 ARBs bind AGRT1 IEA Caenorhabditis elegans 141552 R-ALL-9615735 forasartan [extracellular region] R-CFA-374173 https://reactome.org/PathwayBrowser/#/R-CFA-374173 AGT(34-41) binds to AGTR1 IEA Canis familiaris 141552 R-ALL-9615735 forasartan [extracellular region] R-CFA-9615249 https://reactome.org/PathwayBrowser/#/R-CFA-9615249 ARBs bind AGRT1 IEA Canis familiaris 141552 R-ALL-9615735 forasartan [extracellular region] R-DME-374173 https://reactome.org/PathwayBrowser/#/R-DME-374173 AGT(34-41) binds to AGTR1 IEA Drosophila melanogaster 141552 R-ALL-9615735 forasartan [extracellular region] R-DME-9615249 https://reactome.org/PathwayBrowser/#/R-DME-9615249 ARBs bind AGRT1 IEA Drosophila melanogaster 141552 R-ALL-9615735 forasartan [extracellular region] R-DRE-374173 https://reactome.org/PathwayBrowser/#/R-DRE-374173 AGT(34-41) binds to AGTR1 IEA Danio rerio 141552 R-ALL-9615735 forasartan [extracellular region] R-DRE-9615249 https://reactome.org/PathwayBrowser/#/R-DRE-9615249 ARBs bind AGRT1 IEA Danio rerio 141552 R-ALL-9615735 forasartan [extracellular region] R-GGA-374173 https://reactome.org/PathwayBrowser/#/R-GGA-374173 AGT(34-41) binds to AGTR1 IEA Gallus gallus 141552 R-ALL-9615735 forasartan [extracellular region] R-GGA-9615249 https://reactome.org/PathwayBrowser/#/R-GGA-9615249 ARBs bind AGRT1 IEA Gallus gallus 141552 R-ALL-9615735 forasartan [extracellular region] R-HSA-374173 https://reactome.org/PathwayBrowser/#/R-HSA-374173 AGT(34-41) binds to AGTR1 TAS Homo sapiens 141552 R-ALL-9615735 forasartan [extracellular region] R-HSA-9615249 https://reactome.org/PathwayBrowser/#/R-HSA-9615249 ARBs bind AGRT1 TAS Homo sapiens 141552 R-ALL-9615735 forasartan [extracellular region] R-MMU-374173 https://reactome.org/PathwayBrowser/#/R-MMU-374173 AGT(34-41) binds to AGTR1 IEA Mus musculus 141552 R-ALL-9615735 forasartan [extracellular region] R-MMU-9615249 https://reactome.org/PathwayBrowser/#/R-MMU-9615249 ARBs bind AGRT1 IEA Mus musculus 141552 R-ALL-9615735 forasartan [extracellular region] R-RNO-374173 https://reactome.org/PathwayBrowser/#/R-RNO-374173 AGT(34-41) binds to AGTR1 IEA Rattus norvegicus 141552 R-ALL-9615735 forasartan [extracellular region] R-RNO-9615249 https://reactome.org/PathwayBrowser/#/R-RNO-9615249 ARBs bind AGRT1 IEA Rattus norvegicus 141552 R-ALL-9615735 forasartan [extracellular region] R-SSC-374173 https://reactome.org/PathwayBrowser/#/R-SSC-374173 AGT(34-41) binds to AGTR1 IEA Sus scrofa 141552 R-ALL-9615735 forasartan [extracellular region] R-SSC-9615249 https://reactome.org/PathwayBrowser/#/R-SSC-9615249 ARBs bind AGRT1 IEA Sus scrofa 141634 R-ALL-9617032 F420(ox.) [cytoplasm] R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 141634 R-ALL-9617032 F420(ox.) [cytoplasm] R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 141635 R-ALL-9617033 F420(red.) [cytoplasm] R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 141635 R-ALL-9617033 F420(red.) [cytoplasm] R-HSA-1500781 https://reactome.org/PathwayBrowser/#/R-HSA-1500781 Fgd1 reactivates F420 TAS Homo sapiens 141969 R-ALL-9647938 tipifarnib [cytosol] R-BTA-9647978 https://reactome.org/PathwayBrowser/#/R-BTA-9647978 pro-RAS proteins are farnesylated IEA Bos taurus 141969 R-ALL-9647938 tipifarnib [cytosol] R-BTA-9647987 https://reactome.org/PathwayBrowser/#/R-BTA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Bos taurus 141969 R-ALL-9647938 tipifarnib [cytosol] R-CEL-9647978 https://reactome.org/PathwayBrowser/#/R-CEL-9647978 pro-RAS proteins are farnesylated IEA Caenorhabditis elegans 141969 R-ALL-9647938 tipifarnib [cytosol] R-CEL-9647987 https://reactome.org/PathwayBrowser/#/R-CEL-9647987 FNTB inhibitors bind FNTA:FNTB IEA Caenorhabditis elegans 141969 R-ALL-9647938 tipifarnib [cytosol] R-DDI-9647987 https://reactome.org/PathwayBrowser/#/R-DDI-9647987 FNTB inhibitors bind FNTA:FNTB IEA Dictyostelium discoideum 141969 R-ALL-9647938 tipifarnib [cytosol] R-DME-9647978 https://reactome.org/PathwayBrowser/#/R-DME-9647978 pro-RAS proteins are farnesylated IEA Drosophila melanogaster 141969 R-ALL-9647938 tipifarnib [cytosol] R-DME-9647987 https://reactome.org/PathwayBrowser/#/R-DME-9647987 FNTB inhibitors bind FNTA:FNTB IEA Drosophila melanogaster 141969 R-ALL-9647938 tipifarnib [cytosol] R-DRE-9647978 https://reactome.org/PathwayBrowser/#/R-DRE-9647978 pro-RAS proteins are farnesylated IEA Danio rerio 141969 R-ALL-9647938 tipifarnib [cytosol] R-DRE-9647987 https://reactome.org/PathwayBrowser/#/R-DRE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Danio rerio 141969 R-ALL-9647938 tipifarnib [cytosol] R-GGA-9647978 https://reactome.org/PathwayBrowser/#/R-GGA-9647978 pro-RAS proteins are farnesylated IEA Gallus gallus 141969 R-ALL-9647938 tipifarnib [cytosol] R-GGA-9647987 https://reactome.org/PathwayBrowser/#/R-GGA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Gallus gallus 141969 R-ALL-9647938 tipifarnib [cytosol] R-HSA-9647978 https://reactome.org/PathwayBrowser/#/R-HSA-9647978 pro-RAS proteins are farnesylated TAS Homo sapiens 141969 R-ALL-9647938 tipifarnib [cytosol] R-HSA-9647987 https://reactome.org/PathwayBrowser/#/R-HSA-9647987 FNTB inhibitors bind FNTA:FNTB TAS Homo sapiens 141969 R-ALL-9647938 tipifarnib [cytosol] R-MMU-9647978 https://reactome.org/PathwayBrowser/#/R-MMU-9647978 pro-RAS proteins are farnesylated IEA Mus musculus 141969 R-ALL-9647938 tipifarnib [cytosol] R-MMU-9647987 https://reactome.org/PathwayBrowser/#/R-MMU-9647987 FNTB inhibitors bind FNTA:FNTB IEA Mus musculus 141969 R-ALL-9647938 tipifarnib [cytosol] R-PFA-9647987 https://reactome.org/PathwayBrowser/#/R-PFA-9647987 FNTB inhibitors bind FNTA:FNTB IEA Plasmodium falciparum 141969 R-ALL-9647938 tipifarnib [cytosol] R-RNO-9647978 https://reactome.org/PathwayBrowser/#/R-RNO-9647978 pro-RAS proteins are farnesylated IEA Rattus norvegicus 141969 R-ALL-9647938 tipifarnib [cytosol] R-RNO-9647987 https://reactome.org/PathwayBrowser/#/R-RNO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Rattus norvegicus 141969 R-ALL-9647938 tipifarnib [cytosol] R-SCE-9647987 https://reactome.org/PathwayBrowser/#/R-SCE-9647987 FNTB inhibitors bind FNTA:FNTB IEA Saccharomyces cerevisiae 141969 R-ALL-9647938 tipifarnib [cytosol] R-SPO-9647987 https://reactome.org/PathwayBrowser/#/R-SPO-9647987 FNTB inhibitors bind FNTA:FNTB IEA Schizosaccharomyces pombe 141969 R-ALL-9647938 tipifarnib [cytosol] R-XTR-9647987 https://reactome.org/PathwayBrowser/#/R-XTR-9647987 FNTB inhibitors bind FNTA:FNTB IEA Xenopus tropicalis 142077 R-ALL-9618328 abediterol [extracellular region] R-BTA-390674 https://reactome.org/PathwayBrowser/#/R-BTA-390674 ADRB1 bind ADR,NAd IEA Bos taurus 142077 R-ALL-9618328 abediterol [extracellular region] R-BTA-9611751 https://reactome.org/PathwayBrowser/#/R-BTA-9611751 β1,2-agonists bind ADRB1,2 IEA Bos taurus 142077 R-ALL-9618328 abediterol [extracellular region] R-BTA-9611851 https://reactome.org/PathwayBrowser/#/R-BTA-9611851 ADRB2 bind ADR,NAd IEA Bos taurus 142077 R-ALL-9618328 abediterol [extracellular region] R-CFA-9611751 https://reactome.org/PathwayBrowser/#/R-CFA-9611751 β1,2-agonists bind ADRB1,2 IEA Canis familiaris 142077 R-ALL-9618328 abediterol [extracellular region] R-CFA-9611851 https://reactome.org/PathwayBrowser/#/R-CFA-9611851 ADRB2 bind ADR,NAd IEA Canis familiaris 142077 R-ALL-9618328 abediterol [extracellular region] R-DME-390674 https://reactome.org/PathwayBrowser/#/R-DME-390674 ADRB1 bind ADR,NAd IEA Drosophila melanogaster 142077 R-ALL-9618328 abediterol [extracellular region] R-DME-9611751 https://reactome.org/PathwayBrowser/#/R-DME-9611751 β1,2-agonists bind ADRB1,2 IEA Drosophila melanogaster 142077 R-ALL-9618328 abediterol [extracellular region] R-DME-9611851 https://reactome.org/PathwayBrowser/#/R-DME-9611851 ADRB2 bind ADR,NAd IEA Drosophila melanogaster 142077 R-ALL-9618328 abediterol [extracellular region] R-DRE-390674 https://reactome.org/PathwayBrowser/#/R-DRE-390674 ADRB1 bind ADR,NAd IEA Danio rerio 142077 R-ALL-9618328 abediterol [extracellular region] R-DRE-9611751 https://reactome.org/PathwayBrowser/#/R-DRE-9611751 β1,2-agonists bind ADRB1,2 IEA Danio rerio 142077 R-ALL-9618328 abediterol [extracellular region] R-DRE-9611851 https://reactome.org/PathwayBrowser/#/R-DRE-9611851 ADRB2 bind ADR,NAd IEA Danio rerio 142077 R-ALL-9618328 abediterol [extracellular region] R-GGA-390674 https://reactome.org/PathwayBrowser/#/R-GGA-390674 ADRB1 bind ADR,NAd IEA Gallus gallus 142077 R-ALL-9618328 abediterol [extracellular region] R-GGA-9611751 https://reactome.org/PathwayBrowser/#/R-GGA-9611751 β1,2-agonists bind ADRB1,2 IEA Gallus gallus 142077 R-ALL-9618328 abediterol [extracellular region] R-GGA-9611851 https://reactome.org/PathwayBrowser/#/R-GGA-9611851 ADRB2 bind ADR,NAd IEA Gallus gallus 142077 R-ALL-9618328 abediterol [extracellular region] R-HSA-390674 https://reactome.org/PathwayBrowser/#/R-HSA-390674 ADRB1 bind ADR,NAd TAS Homo sapiens 142077 R-ALL-9618328 abediterol [extracellular region] R-HSA-9611751 https://reactome.org/PathwayBrowser/#/R-HSA-9611751 β1,2-agonists bind ADRB1,2 TAS Homo sapiens 142077 R-ALL-9618328 abediterol [extracellular region] R-HSA-9611851 https://reactome.org/PathwayBrowser/#/R-HSA-9611851 ADRB2 bind ADR,NAd TAS Homo sapiens 142077 R-ALL-9618328 abediterol [extracellular region] R-MMU-390674 https://reactome.org/PathwayBrowser/#/R-MMU-390674 ADRB1 bind ADR,NAd IEA Mus musculus 142077 R-ALL-9618328 abediterol [extracellular region] R-MMU-9611751 https://reactome.org/PathwayBrowser/#/R-MMU-9611751 β1,2-agonists bind ADRB1,2 IEA Mus musculus 142077 R-ALL-9618328 abediterol [extracellular region] R-MMU-9611851 https://reactome.org/PathwayBrowser/#/R-MMU-9611851 ADRB2 bind ADR,NAd IEA Mus musculus 142077 R-ALL-9618328 abediterol [extracellular region] R-RNO-390674 https://reactome.org/PathwayBrowser/#/R-RNO-390674 ADRB1 bind ADR,NAd IEA Rattus norvegicus 142077 R-ALL-9618328 abediterol [extracellular region] R-RNO-9611751 https://reactome.org/PathwayBrowser/#/R-RNO-9611751 β1,2-agonists bind ADRB1,2 IEA Rattus norvegicus 142077 R-ALL-9618328 abediterol [extracellular region] R-RNO-9611851 https://reactome.org/PathwayBrowser/#/R-RNO-9611851 ADRB2 bind ADR,NAd IEA Rattus norvegicus 142077 R-ALL-9618328 abediterol [extracellular region] R-SSC-390674 https://reactome.org/PathwayBrowser/#/R-SSC-390674 ADRB1 bind ADR,NAd IEA Sus scrofa 142077 R-ALL-9618328 abediterol [extracellular region] R-SSC-9611751 https://reactome.org/PathwayBrowser/#/R-SSC-9611751 β1,2-agonists bind ADRB1,2 IEA Sus scrofa 142077 R-ALL-9618328 abediterol [extracellular region] R-SSC-9611851 https://reactome.org/PathwayBrowser/#/R-SSC-9611851 ADRB2 bind ADR,NAd IEA Sus scrofa 142077 R-ALL-9618328 abediterol [extracellular region] R-XTR-390674 https://reactome.org/PathwayBrowser/#/R-XTR-390674 ADRB1 bind ADR,NAd IEA Xenopus tropicalis 142077 R-ALL-9618328 abediterol [extracellular region] R-XTR-9611751 https://reactome.org/PathwayBrowser/#/R-XTR-9611751 β1,2-agonists bind ADRB1,2 IEA Xenopus tropicalis 142077 R-ALL-9618328 abediterol [extracellular region] R-XTR-9611851 https://reactome.org/PathwayBrowser/#/R-XTR-9611851 ADRB2 bind ADR,NAd IEA Xenopus tropicalis 142290 R-ALL-9705522 anagrelide [cytosol] R-BTA-9629679 https://reactome.org/PathwayBrowser/#/R-BTA-9629679 PDE3A inhibitors bind PDE3A IEA Bos taurus 142290 R-ALL-9705522 anagrelide [cytosol] R-CEL-9629679 https://reactome.org/PathwayBrowser/#/R-CEL-9629679 PDE3A inhibitors bind PDE3A IEA Caenorhabditis elegans 142290 R-ALL-9705522 anagrelide [cytosol] R-CFA-9629679 https://reactome.org/PathwayBrowser/#/R-CFA-9629679 PDE3A inhibitors bind PDE3A IEA Canis familiaris 142290 R-ALL-9705522 anagrelide [cytosol] R-DDI-9629679 https://reactome.org/PathwayBrowser/#/R-DDI-9629679 PDE3A inhibitors bind PDE3A IEA Dictyostelium discoideum 142290 R-ALL-9705522 anagrelide [cytosol] R-GGA-9629679 https://reactome.org/PathwayBrowser/#/R-GGA-9629679 PDE3A inhibitors bind PDE3A IEA Gallus gallus 142290 R-ALL-9705522 anagrelide [cytosol] R-HSA-9629679 https://reactome.org/PathwayBrowser/#/R-HSA-9629679 PDE3A inhibitors bind PDE3A TAS Homo sapiens 142290 R-ALL-9705522 anagrelide [cytosol] R-MMU-9629679 https://reactome.org/PathwayBrowser/#/R-MMU-9629679 PDE3A inhibitors bind PDE3A IEA Mus musculus 142290 R-ALL-9705522 anagrelide [cytosol] R-PFA-9629679 https://reactome.org/PathwayBrowser/#/R-PFA-9629679 PDE3A inhibitors bind PDE3A IEA Plasmodium falciparum 142290 R-ALL-9705522 anagrelide [cytosol] R-RNO-9629679 https://reactome.org/PathwayBrowser/#/R-RNO-9629679 PDE3A inhibitors bind PDE3A IEA Rattus norvegicus 142290 R-ALL-9705522 anagrelide [cytosol] R-SSC-9629679 https://reactome.org/PathwayBrowser/#/R-SSC-9629679 PDE3A inhibitors bind PDE3A IEA Sus scrofa 142418 R-ALL-9624761 vibegron [extracellular region] R-BTA-9611839 https://reactome.org/PathwayBrowser/#/R-BTA-9611839 β3-agonists bind ADRB3 IEA Bos taurus 142418 R-ALL-9624761 vibegron [extracellular region] R-BTA-9611852 https://reactome.org/PathwayBrowser/#/R-BTA-9611852 ADRB3 bind ADR,NAd IEA Bos taurus 142418 R-ALL-9624761 vibegron [extracellular region] R-CFA-9611839 https://reactome.org/PathwayBrowser/#/R-CFA-9611839 β3-agonists bind ADRB3 IEA Canis familiaris 142418 R-ALL-9624761 vibegron [extracellular region] R-CFA-9611852 https://reactome.org/PathwayBrowser/#/R-CFA-9611852 ADRB3 bind ADR,NAd IEA Canis familiaris 142418 R-ALL-9624761 vibegron [extracellular region] R-DME-9611839 https://reactome.org/PathwayBrowser/#/R-DME-9611839 β3-agonists bind ADRB3 IEA Drosophila melanogaster 142418 R-ALL-9624761 vibegron [extracellular region] R-DME-9611852 https://reactome.org/PathwayBrowser/#/R-DME-9611852 ADRB3 bind ADR,NAd IEA Drosophila melanogaster 142418 R-ALL-9624761 vibegron [extracellular region] R-GGA-9611839 https://reactome.org/PathwayBrowser/#/R-GGA-9611839 β3-agonists bind ADRB3 IEA Gallus gallus 142418 R-ALL-9624761 vibegron [extracellular region] R-GGA-9611852 https://reactome.org/PathwayBrowser/#/R-GGA-9611852 ADRB3 bind ADR,NAd IEA Gallus gallus 142418 R-ALL-9624761 vibegron [extracellular region] R-HSA-9611839 https://reactome.org/PathwayBrowser/#/R-HSA-9611839 β3-agonists bind ADRB3 TAS Homo sapiens 142418 R-ALL-9624761 vibegron [extracellular region] R-HSA-9611852 https://reactome.org/PathwayBrowser/#/R-HSA-9611852 ADRB3 bind ADR,NAd TAS Homo sapiens 142418 R-ALL-9624761 vibegron [extracellular region] R-MMU-9611839 https://reactome.org/PathwayBrowser/#/R-MMU-9611839 β3-agonists bind ADRB3 IEA Mus musculus 142418 R-ALL-9624761 vibegron [extracellular region] R-MMU-9611852 https://reactome.org/PathwayBrowser/#/R-MMU-9611852 ADRB3 bind ADR,NAd IEA Mus musculus 142418 R-ALL-9624761 vibegron [extracellular region] R-RNO-9611839 https://reactome.org/PathwayBrowser/#/R-RNO-9611839 β3-agonists bind ADRB3 IEA Rattus norvegicus 142418 R-ALL-9624761 vibegron [extracellular region] R-RNO-9611852 https://reactome.org/PathwayBrowser/#/R-RNO-9611852 ADRB3 bind ADR,NAd IEA Rattus norvegicus 142418 R-ALL-9624761 vibegron [extracellular region] R-SSC-9611839 https://reactome.org/PathwayBrowser/#/R-SSC-9611839 β3-agonists bind ADRB3 IEA Sus scrofa 142418 R-ALL-9624761 vibegron [extracellular region] R-SSC-9611852 https://reactome.org/PathwayBrowser/#/R-SSC-9611852 ADRB3 bind ADR,NAd IEA Sus scrofa 142430 R-ALL-9620457 lificiguat [cytosol] R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142430 R-ALL-9620457 lificiguat [cytosol] R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142430 R-ALL-9620457 lificiguat [cytosol] R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142430 R-ALL-9620457 lificiguat [cytosol] R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142430 R-ALL-9620457 lificiguat [cytosol] R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142430 R-ALL-9620457 lificiguat [cytosol] R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142430 R-ALL-9620457 lificiguat [cytosol] R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142430 R-ALL-9620457 lificiguat [cytosol] R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142430 R-ALL-9620457 lificiguat [cytosol] R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142430 R-ALL-9620457 lificiguat [cytosol] R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142431 R-ALL-9620458 praliciguat [cytosol] R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142431 R-ALL-9620458 praliciguat [cytosol] R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142431 R-ALL-9620458 praliciguat [cytosol] R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142431 R-ALL-9620458 praliciguat [cytosol] R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142431 R-ALL-9620458 praliciguat [cytosol] R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142431 R-ALL-9620458 praliciguat [cytosol] R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142431 R-ALL-9620458 praliciguat [cytosol] R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142431 R-ALL-9620458 praliciguat [cytosol] R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142431 R-ALL-9620458 praliciguat [cytosol] R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142431 R-ALL-9620458 praliciguat [cytosol] R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142432 R-ALL-9620463 vericiguat [cytosol] R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142432 R-ALL-9620463 vericiguat [cytosol] R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142432 R-ALL-9620463 vericiguat [cytosol] R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142432 R-ALL-9620463 vericiguat [cytosol] R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142432 R-ALL-9620463 vericiguat [cytosol] R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142432 R-ALL-9620463 vericiguat [cytosol] R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142432 R-ALL-9620463 vericiguat [cytosol] R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142432 R-ALL-9620463 vericiguat [cytosol] R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142432 R-ALL-9620463 vericiguat [cytosol] R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142432 R-ALL-9620463 vericiguat [cytosol] R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142433 R-ALL-9621121 cinaciguat [cytosol] R-BTA-9621179 https://reactome.org/PathwayBrowser/#/R-BTA-9621179 Cinaciguat binds sGC:NO IEA Bos taurus 142433 R-ALL-9621121 cinaciguat [cytosol] R-CFA-9621179 https://reactome.org/PathwayBrowser/#/R-CFA-9621179 Cinaciguat binds sGC:NO IEA Canis familiaris 142433 R-ALL-9621121 cinaciguat [cytosol] R-DME-9621179 https://reactome.org/PathwayBrowser/#/R-DME-9621179 Cinaciguat binds sGC:NO IEA Drosophila melanogaster 142433 R-ALL-9621121 cinaciguat [cytosol] R-DRE-9621179 https://reactome.org/PathwayBrowser/#/R-DRE-9621179 Cinaciguat binds sGC:NO IEA Danio rerio 142433 R-ALL-9621121 cinaciguat [cytosol] R-GGA-9621179 https://reactome.org/PathwayBrowser/#/R-GGA-9621179 Cinaciguat binds sGC:NO IEA Gallus gallus 142433 R-ALL-9621121 cinaciguat [cytosol] R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142433 R-ALL-9621121 cinaciguat [cytosol] R-HSA-9621179 https://reactome.org/PathwayBrowser/#/R-HSA-9621179 Cinaciguat binds sGC:NO TAS Homo sapiens 142433 R-ALL-9621121 cinaciguat [cytosol] R-MMU-9621179 https://reactome.org/PathwayBrowser/#/R-MMU-9621179 Cinaciguat binds sGC:NO IEA Mus musculus 142433 R-ALL-9621121 cinaciguat [cytosol] R-RNO-9621179 https://reactome.org/PathwayBrowser/#/R-RNO-9621179 Cinaciguat binds sGC:NO IEA Rattus norvegicus 142433 R-ALL-9621121 cinaciguat [cytosol] R-SSC-9621179 https://reactome.org/PathwayBrowser/#/R-SSC-9621179 Cinaciguat binds sGC:NO IEA Sus scrofa 142435 R-ALL-9620460 BAY412272 [cytosol] R-BTA-9620456 https://reactome.org/PathwayBrowser/#/R-BTA-9620456 sGC stimulators bind sGC:NO IEA Bos taurus 142435 R-ALL-9620460 BAY412272 [cytosol] R-CFA-9620456 https://reactome.org/PathwayBrowser/#/R-CFA-9620456 sGC stimulators bind sGC:NO IEA Canis familiaris 142435 R-ALL-9620460 BAY412272 [cytosol] R-DME-9620456 https://reactome.org/PathwayBrowser/#/R-DME-9620456 sGC stimulators bind sGC:NO IEA Drosophila melanogaster 142435 R-ALL-9620460 BAY412272 [cytosol] R-DRE-9620456 https://reactome.org/PathwayBrowser/#/R-DRE-9620456 sGC stimulators bind sGC:NO IEA Danio rerio 142435 R-ALL-9620460 BAY412272 [cytosol] R-GGA-9620456 https://reactome.org/PathwayBrowser/#/R-GGA-9620456 sGC stimulators bind sGC:NO IEA Gallus gallus 142435 R-ALL-9620460 BAY412272 [cytosol] R-HSA-392152 https://reactome.org/PathwayBrowser/#/R-HSA-392152 Soluble guanylate cyclase converts GTP to cGMP IEA Homo sapiens 142435 R-ALL-9620460 BAY412272 [cytosol] R-HSA-9620456 https://reactome.org/PathwayBrowser/#/R-HSA-9620456 sGC stimulators bind sGC:NO TAS Homo sapiens 142435 R-ALL-9620460 BAY412272 [cytosol] R-MMU-9620456 https://reactome.org/PathwayBrowser/#/R-MMU-9620456 sGC stimulators bind sGC:NO IEA Mus musculus 142435 R-ALL-9620460 BAY412272 [cytosol] R-RNO-9620456 https://reactome.org/PathwayBrowser/#/R-RNO-9620456 sGC stimulators bind sGC:NO IEA Rattus norvegicus 142435 R-ALL-9620460 BAY412272 [cytosol] R-SSC-9620456 https://reactome.org/PathwayBrowser/#/R-SSC-9620456 sGC stimulators bind sGC:NO IEA Sus scrofa 142437 R-ALL-9603268 lepirudin [extracellular region] R-BTA-140599 https://reactome.org/PathwayBrowser/#/R-BTA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Bos taurus 142437 R-ALL-9603268 lepirudin [extracellular region] R-BTA-158137 https://reactome.org/PathwayBrowser/#/R-BTA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Bos taurus 142437 R-ALL-9603268 lepirudin [extracellular region] R-BTA-158419 https://reactome.org/PathwayBrowser/#/R-BTA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Bos taurus 142437 R-ALL-9603268 lepirudin [extracellular region] R-BTA-9603302 https://reactome.org/PathwayBrowser/#/R-BTA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Bos taurus 142437 R-ALL-9603268 lepirudin [extracellular region] R-CFA-140599 https://reactome.org/PathwayBrowser/#/R-CFA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Canis familiaris 142437 R-ALL-9603268 lepirudin [extracellular region] R-CFA-9603302 https://reactome.org/PathwayBrowser/#/R-CFA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Canis familiaris 142437 R-ALL-9603268 lepirudin [extracellular region] R-GGA-140599 https://reactome.org/PathwayBrowser/#/R-GGA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Gallus gallus 142437 R-ALL-9603268 lepirudin [extracellular region] R-GGA-140840 https://reactome.org/PathwayBrowser/#/R-GGA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Gallus gallus 142437 R-ALL-9603268 lepirudin [extracellular region] R-GGA-158137 https://reactome.org/PathwayBrowser/#/R-GGA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Gallus gallus 142437 R-ALL-9603268 lepirudin [extracellular region] R-GGA-158419 https://reactome.org/PathwayBrowser/#/R-GGA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Gallus gallus 142437 R-ALL-9603268 lepirudin [extracellular region] R-GGA-9603302 https://reactome.org/PathwayBrowser/#/R-GGA-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Gallus gallus 142437 R-ALL-9603268 lepirudin [extracellular region] R-HSA-140599 https://reactome.org/PathwayBrowser/#/R-HSA-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides TAS Homo sapiens 142437 R-ALL-9603268 lepirudin [extracellular region] R-HSA-140840 https://reactome.org/PathwayBrowser/#/R-HSA-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B TAS Homo sapiens 142437 R-ALL-9603268 lepirudin [extracellular region] R-HSA-158137 https://reactome.org/PathwayBrowser/#/R-HSA-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer TAS Homo sapiens 142437 R-ALL-9603268 lepirudin [extracellular region] R-HSA-158419 https://reactome.org/PathwayBrowser/#/R-HSA-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) TAS Homo sapiens 142437 R-ALL-9603268 lepirudin [extracellular region] R-HSA-9603302 https://reactome.org/PathwayBrowser/#/R-HSA-9603302 Factor IIa inhibitors (peptide) bind IIa TAS Homo sapiens 142437 R-ALL-9603268 lepirudin [extracellular region] R-MMU-140599 https://reactome.org/PathwayBrowser/#/R-MMU-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Mus musculus 142437 R-ALL-9603268 lepirudin [extracellular region] R-MMU-140840 https://reactome.org/PathwayBrowser/#/R-MMU-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Mus musculus 142437 R-ALL-9603268 lepirudin [extracellular region] R-MMU-158137 https://reactome.org/PathwayBrowser/#/R-MMU-158137 factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer IEA Mus musculus 142437 R-ALL-9603268 lepirudin [extracellular region] R-MMU-158419 https://reactome.org/PathwayBrowser/#/R-MMU-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Mus musculus 142437 R-ALL-9603268 lepirudin [extracellular region] R-MMU-9603302 https://reactome.org/PathwayBrowser/#/R-MMU-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Mus musculus 142437 R-ALL-9603268 lepirudin [extracellular region] R-RNO-140599 https://reactome.org/PathwayBrowser/#/R-RNO-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Rattus norvegicus 142437 R-ALL-9603268 lepirudin [extracellular region] R-RNO-140840 https://reactome.org/PathwayBrowser/#/R-RNO-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Rattus norvegicus 142437 R-ALL-9603268 lepirudin [extracellular region] R-RNO-158419 https://reactome.org/PathwayBrowser/#/R-RNO-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Rattus norvegicus 142437 R-ALL-9603268 lepirudin [extracellular region] R-RNO-9603302 https://reactome.org/PathwayBrowser/#/R-RNO-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Rattus norvegicus 142437 R-ALL-9603268 lepirudin [extracellular region] R-SSC-140599 https://reactome.org/PathwayBrowser/#/R-SSC-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Sus scrofa 142437 R-ALL-9603268 lepirudin [extracellular region] R-SSC-140840 https://reactome.org/PathwayBrowser/#/R-SSC-140840 fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B IEA Sus scrofa 142437 R-ALL-9603268 lepirudin [extracellular region] R-SSC-158419 https://reactome.org/PathwayBrowser/#/R-SSC-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Sus scrofa 142437 R-ALL-9603268 lepirudin [extracellular region] R-SSC-9603302 https://reactome.org/PathwayBrowser/#/R-SSC-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Sus scrofa 142437 R-ALL-9603268 lepirudin [extracellular region] R-XTR-140599 https://reactome.org/PathwayBrowser/#/R-XTR-140599 factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides IEA Xenopus tropicalis 142437 R-ALL-9603268 lepirudin [extracellular region] R-XTR-158419 https://reactome.org/PathwayBrowser/#/R-XTR-158419 factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) IEA Xenopus tropicalis 142437 R-ALL-9603268 lepirudin [extracellular region] R-XTR-9603302 https://reactome.org/PathwayBrowser/#/R-XTR-9603302 Factor IIa inhibitors (peptide) bind IIa IEA Xenopus tropicalis 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-BTA-390641 https://reactome.org/PathwayBrowser/#/R-BTA-390641 ADRA1A,B,D bind ADR,NAd IEA Bos taurus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-BTA-9623384 https://reactome.org/PathwayBrowser/#/R-BTA-9623384 α1-agonists bind ADRA1A,B,D IEA Bos taurus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-CEL-390641 https://reactome.org/PathwayBrowser/#/R-CEL-390641 ADRA1A,B,D bind ADR,NAd IEA Caenorhabditis elegans 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-CEL-9623384 https://reactome.org/PathwayBrowser/#/R-CEL-9623384 α1-agonists bind ADRA1A,B,D IEA Caenorhabditis elegans 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-CFA-390641 https://reactome.org/PathwayBrowser/#/R-CFA-390641 ADRA1A,B,D bind ADR,NAd IEA Canis familiaris 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-CFA-9623384 https://reactome.org/PathwayBrowser/#/R-CFA-9623384 α1-agonists bind ADRA1A,B,D IEA Canis familiaris 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-DME-390641 https://reactome.org/PathwayBrowser/#/R-DME-390641 ADRA1A,B,D bind ADR,NAd IEA Drosophila melanogaster 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-DME-9623384 https://reactome.org/PathwayBrowser/#/R-DME-9623384 α1-agonists bind ADRA1A,B,D IEA Drosophila melanogaster 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-DRE-390641 https://reactome.org/PathwayBrowser/#/R-DRE-390641 ADRA1A,B,D bind ADR,NAd IEA Danio rerio 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-DRE-9623384 https://reactome.org/PathwayBrowser/#/R-DRE-9623384 α1-agonists bind ADRA1A,B,D IEA Danio rerio 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-GGA-390641 https://reactome.org/PathwayBrowser/#/R-GGA-390641 ADRA1A,B,D bind ADR,NAd IEA Gallus gallus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-GGA-9623384 https://reactome.org/PathwayBrowser/#/R-GGA-9623384 α1-agonists bind ADRA1A,B,D IEA Gallus gallus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-HSA-390641 https://reactome.org/PathwayBrowser/#/R-HSA-390641 ADRA1A,B,D bind ADR,NAd TAS Homo sapiens 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-HSA-9623384 https://reactome.org/PathwayBrowser/#/R-HSA-9623384 α1-agonists bind ADRA1A,B,D TAS Homo sapiens 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-MMU-390641 https://reactome.org/PathwayBrowser/#/R-MMU-390641 ADRA1A,B,D bind ADR,NAd IEA Mus musculus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-MMU-9623384 https://reactome.org/PathwayBrowser/#/R-MMU-9623384 α1-agonists bind ADRA1A,B,D IEA Mus musculus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-RNO-390641 https://reactome.org/PathwayBrowser/#/R-RNO-390641 ADRA1A,B,D bind ADR,NAd IEA Rattus norvegicus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-RNO-9623384 https://reactome.org/PathwayBrowser/#/R-RNO-9623384 α1-agonists bind ADRA1A,B,D IEA Rattus norvegicus 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-SSC-390641 https://reactome.org/PathwayBrowser/#/R-SSC-390641 ADRA1A,B,D bind ADR,NAd IEA Sus scrofa 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-SSC-9623384 https://reactome.org/PathwayBrowser/#/R-SSC-9623384 α1-agonists bind ADRA1A,B,D IEA Sus scrofa 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-XTR-390641 https://reactome.org/PathwayBrowser/#/R-XTR-390641 ADRA1A,B,D bind ADR,NAd IEA Xenopus tropicalis 142452 R-ALL-9626123 dabuzalgron [extracellular region] R-XTR-9623384 https://reactome.org/PathwayBrowser/#/R-XTR-9623384 α1-agonists bind ADRA1A,B,D IEA Xenopus tropicalis 142614 R-ALL-9629218 Gh [nucleoplasm] R-BTA-9629216 https://reactome.org/PathwayBrowser/#/R-BTA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Bos taurus 142614 R-ALL-9629218 Gh [nucleoplasm] R-BTA-9629470 https://reactome.org/PathwayBrowser/#/R-BTA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Bos taurus 142614 R-ALL-9629218 Gh [nucleoplasm] R-CFA-9629216 https://reactome.org/PathwayBrowser/#/R-CFA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Canis familiaris 142614 R-ALL-9629218 Gh [nucleoplasm] R-CFA-9629470 https://reactome.org/PathwayBrowser/#/R-CFA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Canis familiaris 142614 R-ALL-9629218 Gh [nucleoplasm] R-GGA-9629470 https://reactome.org/PathwayBrowser/#/R-GGA-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Gallus gallus 142614 R-ALL-9629218 Gh [nucleoplasm] R-HSA-9629216 https://reactome.org/PathwayBrowser/#/R-HSA-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA TAS Homo sapiens 142614 R-ALL-9629218 Gh [nucleoplasm] R-HSA-9629470 https://reactome.org/PathwayBrowser/#/R-HSA-9629470 NEIL3 cleaves 5-guanidinohydantoin TAS Homo sapiens 142614 R-ALL-9629218 Gh [nucleoplasm] R-MMU-9629216 https://reactome.org/PathwayBrowser/#/R-MMU-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Mus musculus 142614 R-ALL-9629218 Gh [nucleoplasm] R-MMU-9629470 https://reactome.org/PathwayBrowser/#/R-MMU-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Mus musculus 142614 R-ALL-9629218 Gh [nucleoplasm] R-RNO-9629216 https://reactome.org/PathwayBrowser/#/R-RNO-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Rattus norvegicus 142614 R-ALL-9629218 Gh [nucleoplasm] R-RNO-9629470 https://reactome.org/PathwayBrowser/#/R-RNO-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Rattus norvegicus 142614 R-ALL-9629218 Gh [nucleoplasm] R-SSC-9629216 https://reactome.org/PathwayBrowser/#/R-SSC-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Sus scrofa 142614 R-ALL-9629218 Gh [nucleoplasm] R-SSC-9629470 https://reactome.org/PathwayBrowser/#/R-SSC-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Sus scrofa 142614 R-ALL-9629218 Gh [nucleoplasm] R-XTR-9629216 https://reactome.org/PathwayBrowser/#/R-XTR-9629216 NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA IEA Xenopus tropicalis 142614 R-ALL-9629218 Gh [nucleoplasm] R-XTR-9629470 https://reactome.org/PathwayBrowser/#/R-XTR-9629470 NEIL3 cleaves 5-guanidinohydantoin IEA Xenopus tropicalis 142623 R-ALL-9629439 Sp [nucleoplasm] R-BTA-9629492 https://reactome.org/PathwayBrowser/#/R-BTA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Bos taurus 142623 R-ALL-9629439 Sp [nucleoplasm] R-CFA-9629492 https://reactome.org/PathwayBrowser/#/R-CFA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Canis familiaris 142623 R-ALL-9629439 Sp [nucleoplasm] R-GGA-9629492 https://reactome.org/PathwayBrowser/#/R-GGA-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Gallus gallus 142623 R-ALL-9629439 Sp [nucleoplasm] R-HSA-9629483 https://reactome.org/PathwayBrowser/#/R-HSA-9629483 NEIL3 cleaves spiroiminodihydantoin from damaged telomeric DNA IEA Homo sapiens 142623 R-ALL-9629439 Sp [nucleoplasm] R-HSA-9629492 https://reactome.org/PathwayBrowser/#/R-HSA-9629492 NEIL3 cleaves spiroiminodihydantoin TAS Homo sapiens 142623 R-ALL-9629439 Sp [nucleoplasm] R-MMU-9629485 https://reactome.org/PathwayBrowser/#/R-MMU-9629485 Neil3 cleaves spirominodihydantoin from telomeric DNA oligomer TAS Mus musculus 142623 R-ALL-9629439 Sp [nucleoplasm] R-MMU-9629492 https://reactome.org/PathwayBrowser/#/R-MMU-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Mus musculus 142623 R-ALL-9629439 Sp [nucleoplasm] R-RNO-9629492 https://reactome.org/PathwayBrowser/#/R-RNO-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Rattus norvegicus 142623 R-ALL-9629439 Sp [nucleoplasm] R-SSC-9629492 https://reactome.org/PathwayBrowser/#/R-SSC-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Sus scrofa 142623 R-ALL-9629439 Sp [nucleoplasm] R-XTR-9629492 https://reactome.org/PathwayBrowser/#/R-XTR-9629492 NEIL3 cleaves spiroiminodihydantoin IEA Xenopus tropicalis 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9008258 https://reactome.org/PathwayBrowser/#/R-BTA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9008270 https://reactome.org/PathwayBrowser/#/R-BTA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9008271 https://reactome.org/PathwayBrowser/#/R-BTA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9008285 https://reactome.org/PathwayBrowser/#/R-BTA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9009526 https://reactome.org/PathwayBrowser/#/R-BTA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9009533 https://reactome.org/PathwayBrowser/#/R-BTA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9009536 https://reactome.org/PathwayBrowser/#/R-BTA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9009541 https://reactome.org/PathwayBrowser/#/R-BTA-9009541 ESR1 binds to TFF1 gene promoter IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9023860 https://reactome.org/PathwayBrowser/#/R-BTA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9023861 https://reactome.org/PathwayBrowser/#/R-BTA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-BTA-9023884 https://reactome.org/PathwayBrowser/#/R-BTA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Bos taurus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9008258 https://reactome.org/PathwayBrowser/#/R-CFA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9008270 https://reactome.org/PathwayBrowser/#/R-CFA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9008271 https://reactome.org/PathwayBrowser/#/R-CFA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9008285 https://reactome.org/PathwayBrowser/#/R-CFA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9009526 https://reactome.org/PathwayBrowser/#/R-CFA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9009533 https://reactome.org/PathwayBrowser/#/R-CFA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9009536 https://reactome.org/PathwayBrowser/#/R-CFA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9009541 https://reactome.org/PathwayBrowser/#/R-CFA-9009541 ESR1 binds to TFF1 gene promoter IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9023860 https://reactome.org/PathwayBrowser/#/R-CFA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9023861 https://reactome.org/PathwayBrowser/#/R-CFA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-CFA-9023884 https://reactome.org/PathwayBrowser/#/R-CFA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Canis familiaris 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DDI-9023860 https://reactome.org/PathwayBrowser/#/R-DDI-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Dictyostelium discoideum 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9008258 https://reactome.org/PathwayBrowser/#/R-DME-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9008270 https://reactome.org/PathwayBrowser/#/R-DME-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9008285 https://reactome.org/PathwayBrowser/#/R-DME-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9009526 https://reactome.org/PathwayBrowser/#/R-DME-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9009533 https://reactome.org/PathwayBrowser/#/R-DME-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9009536 https://reactome.org/PathwayBrowser/#/R-DME-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9009541 https://reactome.org/PathwayBrowser/#/R-DME-9009541 ESR1 binds to TFF1 gene promoter IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9023860 https://reactome.org/PathwayBrowser/#/R-DME-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9023861 https://reactome.org/PathwayBrowser/#/R-DME-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DME-9023884 https://reactome.org/PathwayBrowser/#/R-DME-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Drosophila melanogaster 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DRE-9009526 https://reactome.org/PathwayBrowser/#/R-DRE-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Danio rerio 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DRE-9009533 https://reactome.org/PathwayBrowser/#/R-DRE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Danio rerio 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DRE-9009541 https://reactome.org/PathwayBrowser/#/R-DRE-9009541 ESR1 binds to TFF1 gene promoter IEA Danio rerio 142773 R-ALL-9008281 estetrol [nucleoplasm] R-DRE-9023860 https://reactome.org/PathwayBrowser/#/R-DRE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Danio rerio 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9008258 https://reactome.org/PathwayBrowser/#/R-GGA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9008270 https://reactome.org/PathwayBrowser/#/R-GGA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9008285 https://reactome.org/PathwayBrowser/#/R-GGA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9009533 https://reactome.org/PathwayBrowser/#/R-GGA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9009536 https://reactome.org/PathwayBrowser/#/R-GGA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9009541 https://reactome.org/PathwayBrowser/#/R-GGA-9009541 ESR1 binds to TFF1 gene promoter IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9023860 https://reactome.org/PathwayBrowser/#/R-GGA-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-GGA-9023884 https://reactome.org/PathwayBrowser/#/R-GGA-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Gallus gallus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008258 https://reactome.org/PathwayBrowser/#/R-HSA-9008258 NCOA3 binds ESR1:estrogen:TFGA gene TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008267 https://reactome.org/PathwayBrowser/#/R-HSA-9008267 ESR1 binds to TGFA gene promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008270 https://reactome.org/PathwayBrowser/#/R-HSA-9008270 NCOA1 binds ESR1:estrogen:TGFA gene TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008271 https://reactome.org/PathwayBrowser/#/R-HSA-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008285 https://reactome.org/PathwayBrowser/#/R-HSA-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9008315 https://reactome.org/PathwayBrowser/#/R-HSA-9008315 TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9009526 https://reactome.org/PathwayBrowser/#/R-HSA-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9009533 https://reactome.org/PathwayBrowser/#/R-HSA-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9009536 https://reactome.org/PathwayBrowser/#/R-HSA-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9009541 https://reactome.org/PathwayBrowser/#/R-HSA-9009541 ESR1 binds to TFF1 gene promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9023859 https://reactome.org/PathwayBrowser/#/R-HSA-9023859 Estrogen-responsive TFF1 gene expression TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9023860 https://reactome.org/PathwayBrowser/#/R-HSA-9023860 Histone acetyltransferases are recruited to the TFF1 gene TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9023861 https://reactome.org/PathwayBrowser/#/R-HSA-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-HSA-9023884 https://reactome.org/PathwayBrowser/#/R-HSA-9023884 NCOA1 recruits EP300 to TGFA promoter TAS Homo sapiens 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9008258 https://reactome.org/PathwayBrowser/#/R-MMU-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9008270 https://reactome.org/PathwayBrowser/#/R-MMU-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9008271 https://reactome.org/PathwayBrowser/#/R-MMU-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9008285 https://reactome.org/PathwayBrowser/#/R-MMU-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9009526 https://reactome.org/PathwayBrowser/#/R-MMU-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9009533 https://reactome.org/PathwayBrowser/#/R-MMU-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9009536 https://reactome.org/PathwayBrowser/#/R-MMU-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9009541 https://reactome.org/PathwayBrowser/#/R-MMU-9009541 ESR1 binds to TFF1 gene promoter IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9023860 https://reactome.org/PathwayBrowser/#/R-MMU-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9023861 https://reactome.org/PathwayBrowser/#/R-MMU-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-MMU-9023884 https://reactome.org/PathwayBrowser/#/R-MMU-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Mus musculus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9008258 https://reactome.org/PathwayBrowser/#/R-RNO-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9008270 https://reactome.org/PathwayBrowser/#/R-RNO-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9008271 https://reactome.org/PathwayBrowser/#/R-RNO-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9008285 https://reactome.org/PathwayBrowser/#/R-RNO-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9009526 https://reactome.org/PathwayBrowser/#/R-RNO-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9009533 https://reactome.org/PathwayBrowser/#/R-RNO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9009536 https://reactome.org/PathwayBrowser/#/R-RNO-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9009541 https://reactome.org/PathwayBrowser/#/R-RNO-9009541 ESR1 binds to TFF1 gene promoter IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9023860 https://reactome.org/PathwayBrowser/#/R-RNO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9023861 https://reactome.org/PathwayBrowser/#/R-RNO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-RNO-9023884 https://reactome.org/PathwayBrowser/#/R-RNO-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Rattus norvegicus 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SCE-9009533 https://reactome.org/PathwayBrowser/#/R-SCE-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Saccharomyces cerevisiae 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SCE-9023860 https://reactome.org/PathwayBrowser/#/R-SCE-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Saccharomyces cerevisiae 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SCE-9023861 https://reactome.org/PathwayBrowser/#/R-SCE-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Saccharomyces cerevisiae 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SPO-9009533 https://reactome.org/PathwayBrowser/#/R-SPO-9009533 TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter IEA Schizosaccharomyces pombe 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SPO-9023860 https://reactome.org/PathwayBrowser/#/R-SPO-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Schizosaccharomyces pombe 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SPO-9023861 https://reactome.org/PathwayBrowser/#/R-SPO-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Schizosaccharomyces pombe 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9008258 https://reactome.org/PathwayBrowser/#/R-SSC-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9008270 https://reactome.org/PathwayBrowser/#/R-SSC-9008270 NCOA1 binds ESR1:estrogen:TGFA gene IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9008271 https://reactome.org/PathwayBrowser/#/R-SSC-9008271 CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9008285 https://reactome.org/PathwayBrowser/#/R-SSC-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9009526 https://reactome.org/PathwayBrowser/#/R-SSC-9009526 CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9009536 https://reactome.org/PathwayBrowser/#/R-SSC-9009536 DDX5 binds ESR1:estrogen:TFF1 gene promoter IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9009541 https://reactome.org/PathwayBrowser/#/R-SSC-9009541 ESR1 binds to TFF1 gene promoter IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9023860 https://reactome.org/PathwayBrowser/#/R-SSC-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9023861 https://reactome.org/PathwayBrowser/#/R-SSC-9023861 PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-SSC-9023884 https://reactome.org/PathwayBrowser/#/R-SSC-9023884 NCOA1 recruits EP300 to TGFA promoter IEA Sus scrofa 142773 R-ALL-9008281 estetrol [nucleoplasm] R-XTR-9008258 https://reactome.org/PathwayBrowser/#/R-XTR-9008258 NCOA3 binds ESR1:estrogen:TFGA gene IEA Xenopus tropicalis 142773 R-ALL-9008281 estetrol [nucleoplasm] R-XTR-9008285 https://reactome.org/PathwayBrowser/#/R-XTR-9008285 NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 IEA Xenopus tropicalis 142773 R-ALL-9008281 estetrol [nucleoplasm] R-XTR-9023860 https://reactome.org/PathwayBrowser/#/R-XTR-9023860 Histone acetyltransferases are recruited to the TFF1 gene IEA Xenopus tropicalis 142774 R-ALL-6788977 nitryl chloride [phagocytic vesicle lumen] R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 142774 R-ALL-6788977 nitryl chloride [phagocytic vesicle lumen] R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 142774 R-ALL-6788977 nitryl chloride [phagocytic vesicle lumen] R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 142968 R-ALL-9636495 LM [cytosol] R-HSA-9697064 https://reactome.org/PathwayBrowser/#/R-HSA-9697064 LprG binds to LAM,LM TAS Homo sapiens 142968 R-ALL-9636434 LM [peptidoglycan-based cell wall] R-HSA-9697070 https://reactome.org/PathwayBrowser/#/R-HSA-9697070 LprG dissociates from LAM,LM TAS Homo sapiens 142968 R-ALL-9636495 LM [cytosol] R-HSA-9697077 https://reactome.org/PathwayBrowser/#/R-HSA-9697077 Rv1410c transports LprG:LM,LAM from cytosol to the cell wall TAS Homo sapiens 142968 R-ALL-9636434 LM [peptidoglycan-based cell wall] R-HSA-9697077 https://reactome.org/PathwayBrowser/#/R-HSA-9697077 Rv1410c transports LprG:LM,LAM from cytosol to the cell wall TAS Homo sapiens 143082 R-ALL-9635420 mycocerosyl [cytosol] R-MTU-9635440 https://reactome.org/PathwayBrowser/#/R-MTU-9635440 PapA5 transforms mycocerosyl to PDIM TAS Mycobacterium tuberculosis 143082 R-ALL-9635420 mycocerosyl [cytosol] R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 143085 R-ALL-9635426 PDIM [cytosol] R-MTU-9635440 https://reactome.org/PathwayBrowser/#/R-MTU-9635440 PapA5 transforms mycocerosyl to PDIM TAS Mycobacterium tuberculosis 143085 R-ALL-9635426 PDIM [cytosol] R-MTU-9637589 https://reactome.org/PathwayBrowser/#/R-MTU-9637589 MmpL7 transports PDIM from the cytosol to the cell wall TAS Mycobacterium tuberculosis 143085 R-ALL-9637592 PDIM [peptidoglycan-based cell wall] R-MTU-9637589 https://reactome.org/PathwayBrowser/#/R-MTU-9637589 MmpL7 transports PDIM from the cytosol to the cell wall TAS Mycobacterium tuberculosis 143117 R-ALL-9702126 lorlatinib [cytosol] R-BTA-201521 https://reactome.org/PathwayBrowser/#/R-BTA-201521 ALK autophosphorylation IEA Bos taurus 143117 R-ALL-9702126 lorlatinib [cytosol] R-BTA-9700662 https://reactome.org/PathwayBrowser/#/R-BTA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Bos taurus 143117 R-ALL-9702126 lorlatinib [cytosol] R-CFA-201521 https://reactome.org/PathwayBrowser/#/R-CFA-201521 ALK autophosphorylation IEA Canis familiaris 143117 R-ALL-9702126 lorlatinib [cytosol] R-CFA-9700662 https://reactome.org/PathwayBrowser/#/R-CFA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Canis familiaris 143117 R-ALL-9702126 lorlatinib [cytosol] R-DRE-201521 https://reactome.org/PathwayBrowser/#/R-DRE-201521 ALK autophosphorylation IEA Danio rerio 143117 R-ALL-9702126 lorlatinib [cytosol] R-DRE-9700662 https://reactome.org/PathwayBrowser/#/R-DRE-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Danio rerio 143117 R-ALL-9702126 lorlatinib [cytosol] R-GGA-201521 https://reactome.org/PathwayBrowser/#/R-GGA-201521 ALK autophosphorylation IEA Gallus gallus 143117 R-ALL-9702126 lorlatinib [cytosol] R-GGA-9700662 https://reactome.org/PathwayBrowser/#/R-GGA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Gallus gallus 143117 R-ALL-9702126 lorlatinib [cytosol] R-HSA-201521 https://reactome.org/PathwayBrowser/#/R-HSA-201521 ALK autophosphorylation TAS Homo sapiens 143117 R-ALL-9702126 lorlatinib [cytosol] R-HSA-9700131 https://reactome.org/PathwayBrowser/#/R-HSA-9700131 ALK mutants bind type I TKIs TAS Homo sapiens 143117 R-ALL-9702126 lorlatinib [cytosol] R-HSA-9700662 https://reactome.org/PathwayBrowser/#/R-HSA-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs TAS Homo sapiens 143117 R-ALL-9702126 lorlatinib [cytosol] R-HSA-9715355 https://reactome.org/PathwayBrowser/#/R-HSA-9715355 lorlatinib-resistant ALK mutants don't bind lorlatinib TAS Homo sapiens 143117 R-ALL-9702126 lorlatinib [cytosol] R-MMU-201521 https://reactome.org/PathwayBrowser/#/R-MMU-201521 ALK autophosphorylation IEA Mus musculus 143117 R-ALL-9702126 lorlatinib [cytosol] R-MMU-9700662 https://reactome.org/PathwayBrowser/#/R-MMU-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Mus musculus 143117 R-ALL-9702126 lorlatinib [cytosol] R-RNO-201521 https://reactome.org/PathwayBrowser/#/R-RNO-201521 ALK autophosphorylation IEA Rattus norvegicus 143117 R-ALL-9702126 lorlatinib [cytosol] R-RNO-9700662 https://reactome.org/PathwayBrowser/#/R-RNO-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Rattus norvegicus 143117 R-ALL-9702126 lorlatinib [cytosol] R-SSC-201521 https://reactome.org/PathwayBrowser/#/R-SSC-201521 ALK autophosphorylation IEA Sus scrofa 143117 R-ALL-9702126 lorlatinib [cytosol] R-SSC-9700662 https://reactome.org/PathwayBrowser/#/R-SSC-9700662 Liganded-ALK dimer binds type I ALK-binding TKIs IEA Sus scrofa 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 143554 R-ALL-9731304 8-oxo-GDP(3-) [cytosol] R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-BTA-9840470 https://reactome.org/PathwayBrowser/#/R-BTA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Bos taurus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-CEL-9840470 https://reactome.org/PathwayBrowser/#/R-CEL-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Caenorhabditis elegans 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-CFA-9840470 https://reactome.org/PathwayBrowser/#/R-CFA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Canis familiaris 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-DDI-9840470 https://reactome.org/PathwayBrowser/#/R-DDI-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Dictyostelium discoideum 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-DME-9840470 https://reactome.org/PathwayBrowser/#/R-DME-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Drosophila melanogaster 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-GGA-9840470 https://reactome.org/PathwayBrowser/#/R-GGA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Gallus gallus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-HSA-9840470 https://reactome.org/PathwayBrowser/#/R-HSA-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands TAS Homo sapiens 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-MMU-9840470 https://reactome.org/PathwayBrowser/#/R-MMU-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Mus musculus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-RNO-9840470 https://reactome.org/PathwayBrowser/#/R-RNO-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Rattus norvegicus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 143594 R-ALL-9840484 Gal2Cer [multivesicular body, internal vesicle membrane] R-SSC-9840470 https://reactome.org/PathwayBrowser/#/R-SSC-9840470 PSAP(195-273) dimer:PE binds and mobilizes ligands IEA Sus scrofa 143594 R-ALL-9840487 Gal2Cer [lysosomal lumen] R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 143788 R-ALL-111338 PRGA [cytosol] R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 143788 R-ALL-111338 PRGA [cytosol] R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 143788 R-ALL-111338 PRGA [cytosol] R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 143788 R-ALL-111338 PRGA [cytosol] R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 143788 R-ALL-111338 PRGA [cytosol] R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 143788 R-ALL-111338 PRGA [cytosol] R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 143788 R-ALL-111338 PRGA [cytosol] R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 143788 R-ALL-111338 PRGA [cytosol] R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 143788 R-ALL-111338 PRGA [cytosol] R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 143788 R-ALL-111338 PRGA [cytosol] R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 143788 R-ALL-111338 PRGA [cytosol] R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 143788 R-ALL-111338 PRGA [cytosol] R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 143788 R-ALL-111338 PRGA [cytosol] R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 143788 R-ALL-111338 PRGA [cytosol] R-GGA-419153 https://reactome.org/PathwayBrowser/#/R-GGA-419153 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate TAS Gallus gallus 143788 R-ALL-111338 PRGA [cytosol] R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 143788 R-ALL-111338 PRGA [cytosol] R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 143788 R-ALL-111338 PRGA [cytosol] R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 143788 R-ALL-111338 PRGA [cytosol] R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 143788 R-ALL-111338 PRGA [cytosol] R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 143788 R-ALL-111338 PRGA [cytosol] R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 143788 R-ALL-111338 PRGA [cytosol] R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 143788 R-ALL-111338 PRGA [cytosol] R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 143788 R-ALL-111338 PRGA [cytosol] R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 143788 R-ALL-111338 PRGA [cytosol] R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 143788 R-ALL-111338 PRGA [cytosol] R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 143788 R-ALL-111338 PRGA [cytosol] R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 143788 R-ALL-111338 PRGA [cytosol] R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 143788 R-ALL-111338 PRGA [cytosol] R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 143788 R-ALL-111338 PRGA [cytosol] R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 143788 R-ALL-111338 PRGA [cytosol] R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681314 https://reactome.org/PathwayBrowser/#/R-HSA-9681314 Replication transcription complex binds SARS-CoV-1 genomic RNA TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681651 https://reactome.org/PathwayBrowser/#/R-HSA-9681651 nsp8 generates RNA primers TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 143976 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9682695 https://reactome.org/PathwayBrowser/#/R-HSA-9682695 nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template TAS Homo sapiens 143976 R-COV-9685914 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9683618 https://reactome.org/PathwayBrowser/#/R-HSA-9683618 mRNA3 is translated to protein 3a TAS Homo sapiens 143976 R-COV-9685920 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9683622 https://reactome.org/PathwayBrowser/#/R-HSA-9683622 mRNA5 is translated to protein M TAS Homo sapiens 143976 R-COV-9685916 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9683624 https://reactome.org/PathwayBrowser/#/R-HSA-9683624 mRNA2 is translated to Spike TAS Homo sapiens 143976 R-COV-9685917 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9683656 https://reactome.org/PathwayBrowser/#/R-HSA-9683656 mRNA4 is translated to protein E TAS Homo sapiens 143976 R-COV-9685921 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9683735 https://reactome.org/PathwayBrowser/#/R-HSA-9683735 mRNA9 is translated to Nucleoprotein TAS Homo sapiens 143976 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9684030 https://reactome.org/PathwayBrowser/#/R-HSA-9684030 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 143976 R-COV-9684636 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684032 https://reactome.org/PathwayBrowser/#/R-HSA-9684032 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 143976 R-COV-9685890 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685889 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685888 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685894 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685893 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685887 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685886 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685885 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9684033 https://reactome.org/PathwayBrowser/#/R-HSA-9684033 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684229 https://reactome.org/PathwayBrowser/#/R-HSA-9684229 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684234 https://reactome.org/PathwayBrowser/#/R-HSA-9684234 Encapsidation of SARS coronavirus genomic RNA TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684238 https://reactome.org/PathwayBrowser/#/R-HSA-9684238 E and N are recruited to the M lattice TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684241 https://reactome.org/PathwayBrowser/#/R-HSA-9684241 Recruitment of Spike trimer to assembling virion TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684277 https://reactome.org/PathwayBrowser/#/R-HSA-9684277 mRNA1 is translated to pp1ab TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9684301 https://reactome.org/PathwayBrowser/#/R-HSA-9684301 mRNA1 is translated to pp1a TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 143976 R-COV-9684636 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685519 https://reactome.org/PathwayBrowser/#/R-HSA-9685519 Polyadenylation of SARS-CoV-1 genomic RNA (plus strand) TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685531 https://reactome.org/PathwayBrowser/#/R-HSA-9685531 SARS virus buds into ERGIC lumen TAS Homo sapiens 143976 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9685597 https://reactome.org/PathwayBrowser/#/R-HSA-9685597 RTC binds SARS-CoV-1 genomic RNA complement (minus strand) TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9685639 https://reactome.org/PathwayBrowser/#/R-HSA-9685639 Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching TAS Homo sapiens 143976 R-COV-9685921 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685914 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685916 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685920 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685917 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685890 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685889 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685888 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685894 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685893 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685887 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685886 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685885 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685922 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685915 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685918 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9685906 https://reactome.org/PathwayBrowser/#/R-HSA-9685906 Polyadenylation of SARS-CoV-1 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9686174 https://reactome.org/PathwayBrowser/#/R-HSA-9686174 Accessory proteins are recruited to the maturing virion TAS Homo sapiens 143976 R-COV-9685513 m7G(5')pppAm-capped SARS-CoV-1 genomic RNA complement (minus strand) [cytosol] R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9693589 https://reactome.org/PathwayBrowser/#/R-HSA-9693589 SARS-CoV-1 dsRNA intermediates bind DDX58 TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9693590 https://reactome.org/PathwayBrowser/#/R-HSA-9693590 SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694265 https://reactome.org/PathwayBrowser/#/R-HSA-9694265 nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694274 https://reactome.org/PathwayBrowser/#/R-HSA-9694274 mRNA1 is translated to pp1ab IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694277 https://reactome.org/PathwayBrowser/#/R-HSA-9694277 nsp8 generates RNA primers IEA Homo sapiens 143976 R-COV-9694622 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9694280 https://reactome.org/PathwayBrowser/#/R-HSA-9694280 mRNA4 is translated to protein E TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694281 https://reactome.org/PathwayBrowser/#/R-HSA-9694281 Encapsidation of SARS coronavirus genomic RNA IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694287 https://reactome.org/PathwayBrowser/#/R-HSA-9694287 Cleavage of S protein into S1:S2 TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694334 https://reactome.org/PathwayBrowser/#/R-HSA-9694334 mRNA1 is translated to pp1a IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694344 https://reactome.org/PathwayBrowser/#/R-HSA-9694344 Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching IEA Homo sapiens 143976 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9694370 https://reactome.org/PathwayBrowser/#/R-HSA-9694370 mRNA9a is translated to Nucleoprotein TAS Homo sapiens 143976 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694444 https://reactome.org/PathwayBrowser/#/R-HSA-9694444 E and N are recruited to the M lattice IEA Homo sapiens 143976 R-COV-9694503 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9694447 https://reactome.org/PathwayBrowser/#/R-HSA-9694447 mRNA2 is translated to Spike TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694454 https://reactome.org/PathwayBrowser/#/R-HSA-9694454 Replication transcription complex binds SARS-CoV-2 genomic RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694455 https://reactome.org/PathwayBrowser/#/R-HSA-9694455 SUMO-p-N protein dimer binds genomic RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 143976 R-COV-9694619 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694471 https://reactome.org/PathwayBrowser/#/R-HSA-9694471 Polyadenylation of SARS-CoV-2 genomic RNA (plus strand) TAS Homo sapiens 143976 R-COV-9792628 GpppAm-mRNA5 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792630 GpppAm-mRNA4 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792624 GpppAm-mRNA9 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792637 GpppAm-mRNA3 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792638 GpppAm-mRNA6 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792622 GpppAm-mRNA8 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792633 GpppAm-mRNA7 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9792632 GpppAm-mRNA2 [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694495 https://reactome.org/PathwayBrowser/#/R-HSA-9694495 RTC binds SARS-CoV-2 genomic RNA complement (minus strand) IEA Homo sapiens 143976 R-COV-9694352 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694710 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694613 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694757 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694699 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694523 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694266 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694350 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9694499 https://reactome.org/PathwayBrowser/#/R-HSA-9694499 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 143976 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694521 https://reactome.org/PathwayBrowser/#/R-HSA-9694521 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694528 https://reactome.org/PathwayBrowser/#/R-HSA-9694528 Accessory proteins are recruited to the maturing virion IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694553 https://reactome.org/PathwayBrowser/#/R-HSA-9694553 Recruitment of Spike trimer to assembling virion IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694579 https://reactome.org/PathwayBrowser/#/R-HSA-9694579 Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell TAS Homo sapiens 143976 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694633 https://reactome.org/PathwayBrowser/#/R-HSA-9694633 SARS virus buds into ERGIC lumen IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694641 https://reactome.org/PathwayBrowser/#/R-HSA-9694641 Viral release IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694661 https://reactome.org/PathwayBrowser/#/R-HSA-9694661 TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694677 https://reactome.org/PathwayBrowser/#/R-HSA-9694677 ZCRB1 binds 5'UTR of SARS-CoV-2 genomic RNA IEA Homo sapiens 143976 R-COV-9694456 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9694681 https://reactome.org/PathwayBrowser/#/R-HSA-9694681 mRNA5 is translated to protein M TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9694689 https://reactome.org/PathwayBrowser/#/R-HSA-9694689 Fusion and Release of SARS-CoV-2 Nucleocapsid IEA Homo sapiens 143976 R-COV-9694619 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694721 https://reactome.org/PathwayBrowser/#/R-HSA-9694721 nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694723 https://reactome.org/PathwayBrowser/#/R-HSA-9694723 Uncoating of SARS-CoV-2 Genome IEA Homo sapiens 143976 R-COV-9694325 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694352 m7G(5')pppAm-mRNA5 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694710 m7G(5')pppAm-mRNA7 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694613 m7G(5')pppAm-mRNA2 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694757 m7G(5')pppAm-mRNA6 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694699 m7G(5')pppAm-mRNA4 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694523 m7G(5')pppAm-mRNA9 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694266 m7G(5')pppAm-mRNA3 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694350 m7G(5')pppAm-mRNA8 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694354 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694496 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694503 m7G(5')pppAm-capped,polyadenylated mRNA2 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694456 m7G(5')pppAm-capped,polyadenylated mRNA5 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694622 m7G(5')pppAm-capped,polyadenylated mRNA4 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694285 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9694733 https://reactome.org/PathwayBrowser/#/R-HSA-9694733 Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 143976 R-COV-9694325 m7G(5')pppAm-capped,polyadenylated mRNA3 [cytosol] R-HSA-9694794 https://reactome.org/PathwayBrowser/#/R-HSA-9694794 mRNA3 is translated to protein 3a TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9697423 https://reactome.org/PathwayBrowser/#/R-HSA-9697423 Endocytosis of SARS-CoV-2 Virion IEA Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9698988 https://reactome.org/PathwayBrowser/#/R-HSA-9698988 Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9699007 https://reactome.org/PathwayBrowser/#/R-HSA-9699007 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis TAS Homo sapiens 143976 R-COV-9685518 m7G(5')pppAm-capped, polyadenylated SARS-CoV-1 genomic RNA (plus strand) [cytosol] R-HSA-9705961 https://reactome.org/PathwayBrowser/#/R-HSA-9705961 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9707827 https://reactome.org/PathwayBrowser/#/R-HSA-9707827 Spike binds Spike inhibitors TAS Homo sapiens 143976 R-COV-9694285 m7G(5')pppAm-capped,polyadenylated mRNA6 [cytosol] R-HSA-9727292 https://reactome.org/PathwayBrowser/#/R-HSA-9727292 mRNA6 is translated to protein 6 TAS Homo sapiens 143976 R-COV-9694496 m7G(5')pppAm-capped,polyadenylated mRNA7 [cytosol] R-HSA-9727297 https://reactome.org/PathwayBrowser/#/R-HSA-9727297 mRNA7 is translated to protein 7a TAS Homo sapiens 143976 R-COV-9694513 m7G(5')pppAm-capped,polyadenylated-mRNA9 [cytosol] R-HSA-9727303 https://reactome.org/PathwayBrowser/#/R-HSA-9727303 mRNA9 is translated to protein 9b TAS Homo sapiens 143976 R-COV-9694354 m7G(5')pppAm-capped,polyadenylated mRNA8 [cytosol] R-HSA-9727305 https://reactome.org/PathwayBrowser/#/R-HSA-9727305 mRNA8 is translated to protein 8 TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9754745 https://reactome.org/PathwayBrowser/#/R-HSA-9754745 IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9755252 https://reactome.org/PathwayBrowser/#/R-HSA-9755252 nsp15 cleaves viral poly(U)-RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9755258 https://reactome.org/PathwayBrowser/#/R-HSA-9755258 DDX58 binds SARS-CoV-2 dsRNA intermediates TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9755368 https://reactome.org/PathwayBrowser/#/R-HSA-9755368 TLR2:TLR1 binds SARS-CoV-2 E pentamer TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9756574 https://reactome.org/PathwayBrowser/#/R-HSA-9756574 SARS-CoV-2 S binds SFTPD 12mer TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 143976 R-COV-9694603 m7G(5')pppAm-capped SARS-CoV-2 genomic RNA complement (minus strand) [cytosol] R-HSA-9759709 https://reactome.org/PathwayBrowser/#/R-HSA-9759709 CNBP binds SARS-CoV-2 G-rich RNA TAS Homo sapiens 143976 R-COV-9694393 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [cytosol] R-HSA-9760510 https://reactome.org/PathwayBrowser/#/R-HSA-9760510 LARP1 binds SARS-CoV-2 RNA TAS Homo sapiens 143976 R-COV-9697431 m7G(5')pppAm-capped, polyadenylated SARS-CoV-2 genomic RNA (plus strand) [viral capsid] R-HSA-9769949 https://reactome.org/PathwayBrowser/#/R-HSA-9769949 FURIN Mediated SARS-CoV-2 Spike Protein Cleavage TAS Homo sapiens 143976 R-COV-9792628 GpppAm-mRNA5 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792630 GpppAm-mRNA4 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792624 GpppAm-mRNA9 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792637 GpppAm-mRNA3 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792638 GpppAm-mRNA6 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792622 GpppAm-mRNA8 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792633 GpppAm-mRNA7 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 143976 R-COV-9792632 GpppAm-mRNA2 [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-BTA-9693324 https://reactome.org/PathwayBrowser/#/R-BTA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Bos taurus 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-CFA-9693324 https://reactome.org/PathwayBrowser/#/R-CFA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Canis familiaris 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-GGA-9693324 https://reactome.org/PathwayBrowser/#/R-GGA-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Gallus gallus 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-HSA-9693324 https://reactome.org/PathwayBrowser/#/R-HSA-9693324 Disulfiram covalently modifies Cys191 in GSDMD TAS Homo sapiens 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-MMU-9693324 https://reactome.org/PathwayBrowser/#/R-MMU-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Mus musculus 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-RNO-9693324 https://reactome.org/PathwayBrowser/#/R-RNO-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Rattus norvegicus 144353 R-ALL-9693333 diethyldithiocarbamic acid [cytosol] R-SSC-9693324 https://reactome.org/PathwayBrowser/#/R-SSC-9693324 Disulfiram covalently modifies Cys191 in GSDMD IEA Sus scrofa 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 144842 R-ALL-9731626 N(6)-methyl-AMP(2-) [cytosol] R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 145365 R-ALL-9674072 crenolanib [cytosol] R-BTA-389083 https://reactome.org/PathwayBrowser/#/R-BTA-389083 Autophosphorylation of PDGF alpha receptors IEA Bos taurus 145365 R-ALL-9674072 crenolanib [cytosol] R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 145365 R-ALL-9674072 crenolanib [cytosol] R-BTA-9674093 https://reactome.org/PathwayBrowser/#/R-BTA-9674093 PDGFRs bind type I TKI IEA Bos taurus 145365 R-ALL-9674072 crenolanib [cytosol] R-CEL-389083 https://reactome.org/PathwayBrowser/#/R-CEL-389083 Autophosphorylation of PDGF alpha receptors IEA Caenorhabditis elegans 145365 R-ALL-9674072 crenolanib [cytosol] R-CEL-9674093 https://reactome.org/PathwayBrowser/#/R-CEL-9674093 PDGFRs bind type I TKI IEA Caenorhabditis elegans 145365 R-ALL-9674072 crenolanib [cytosol] R-CFA-389083 https://reactome.org/PathwayBrowser/#/R-CFA-389083 Autophosphorylation of PDGF alpha receptors IEA Canis familiaris 145365 R-ALL-9674072 crenolanib [cytosol] R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 145365 R-ALL-9674072 crenolanib [cytosol] R-CFA-9674093 https://reactome.org/PathwayBrowser/#/R-CFA-9674093 PDGFRs bind type I TKI IEA Canis familiaris 145365 R-ALL-9674072 crenolanib [cytosol] R-DME-389083 https://reactome.org/PathwayBrowser/#/R-DME-389083 Autophosphorylation of PDGF alpha receptors IEA Drosophila melanogaster 145365 R-ALL-9674072 crenolanib [cytosol] R-DME-9674093 https://reactome.org/PathwayBrowser/#/R-DME-9674093 PDGFRs bind type I TKI IEA Drosophila melanogaster 145365 R-ALL-9674072 crenolanib [cytosol] R-DRE-389083 https://reactome.org/PathwayBrowser/#/R-DRE-389083 Autophosphorylation of PDGF alpha receptors IEA Danio rerio 145365 R-ALL-9674072 crenolanib [cytosol] R-DRE-9674093 https://reactome.org/PathwayBrowser/#/R-DRE-9674093 PDGFRs bind type I TKI IEA Danio rerio 145365 R-ALL-9674072 crenolanib [cytosol] R-GGA-389083 https://reactome.org/PathwayBrowser/#/R-GGA-389083 Autophosphorylation of PDGF alpha receptors IEA Gallus gallus 145365 R-ALL-9674072 crenolanib [cytosol] R-GGA-9674093 https://reactome.org/PathwayBrowser/#/R-GGA-9674093 PDGFRs bind type I TKI IEA Gallus gallus 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-389083 https://reactome.org/PathwayBrowser/#/R-HSA-389083 Autophosphorylation of PDGF alpha receptors TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9674093 https://reactome.org/PathwayBrowser/#/R-HSA-9674093 PDGFRs bind type I TKI TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9674427 https://reactome.org/PathwayBrowser/#/R-HSA-9674427 PDGFR mutants bind type I TKIs TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-HSA-9702583 https://reactome.org/PathwayBrowser/#/R-HSA-9702583 crenolanib-resistant FLT3 mutants don't bind crenolanib TAS Homo sapiens 145365 R-ALL-9674072 crenolanib [cytosol] R-MMU-389083 https://reactome.org/PathwayBrowser/#/R-MMU-389083 Autophosphorylation of PDGF alpha receptors IEA Mus musculus 145365 R-ALL-9674072 crenolanib [cytosol] R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 145365 R-ALL-9674072 crenolanib [cytosol] R-MMU-9674093 https://reactome.org/PathwayBrowser/#/R-MMU-9674093 PDGFRs bind type I TKI IEA Mus musculus 145365 R-ALL-9674072 crenolanib [cytosol] R-RNO-389083 https://reactome.org/PathwayBrowser/#/R-RNO-389083 Autophosphorylation of PDGF alpha receptors IEA Rattus norvegicus 145365 R-ALL-9674072 crenolanib [cytosol] R-RNO-9674093 https://reactome.org/PathwayBrowser/#/R-RNO-9674093 PDGFRs bind type I TKI IEA Rattus norvegicus 145365 R-ALL-9674072 crenolanib [cytosol] R-SSC-389083 https://reactome.org/PathwayBrowser/#/R-SSC-389083 Autophosphorylation of PDGF alpha receptors IEA Sus scrofa 145365 R-ALL-9674072 crenolanib [cytosol] R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 145365 R-ALL-9674072 crenolanib [cytosol] R-SSC-9674093 https://reactome.org/PathwayBrowser/#/R-SSC-9674093 PDGFRs bind type I TKI IEA Sus scrofa 145371 R-ALL-9657530 binimetinib [cytosol] R-BTA-5672973 https://reactome.org/PathwayBrowser/#/R-BTA-5672973 MAP2Ks phosphorylate MAPKs IEA Bos taurus 145371 R-ALL-9657530 binimetinib [cytosol] R-BTA-9657606 https://reactome.org/PathwayBrowser/#/R-BTA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Bos taurus 145371 R-ALL-9657530 binimetinib [cytosol] R-CEL-5672973 https://reactome.org/PathwayBrowser/#/R-CEL-5672973 MAP2Ks phosphorylate MAPKs IEA Caenorhabditis elegans 145371 R-ALL-9657530 binimetinib [cytosol] R-CEL-9657606 https://reactome.org/PathwayBrowser/#/R-CEL-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Caenorhabditis elegans 145371 R-ALL-9657530 binimetinib [cytosol] R-CFA-5672973 https://reactome.org/PathwayBrowser/#/R-CFA-5672973 MAP2Ks phosphorylate MAPKs IEA Canis familiaris 145371 R-ALL-9657530 binimetinib [cytosol] R-CFA-9657606 https://reactome.org/PathwayBrowser/#/R-CFA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Canis familiaris 145371 R-ALL-9657530 binimetinib [cytosol] R-DME-5672973 https://reactome.org/PathwayBrowser/#/R-DME-5672973 MAP2Ks phosphorylate MAPKs IEA Drosophila melanogaster 145371 R-ALL-9657530 binimetinib [cytosol] R-DME-9657606 https://reactome.org/PathwayBrowser/#/R-DME-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Drosophila melanogaster 145371 R-ALL-9657530 binimetinib [cytosol] R-GGA-5672973 https://reactome.org/PathwayBrowser/#/R-GGA-5672973 MAP2Ks phosphorylate MAPKs IEA Gallus gallus 145371 R-ALL-9657530 binimetinib [cytosol] R-GGA-9657606 https://reactome.org/PathwayBrowser/#/R-GGA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Gallus gallus 145371 R-ALL-9657530 binimetinib [cytosol] R-HSA-5672973 https://reactome.org/PathwayBrowser/#/R-HSA-5672973 MAP2Ks phosphorylate MAPKs TAS Homo sapiens 145371 R-ALL-9657530 binimetinib [cytosol] R-HSA-9657606 https://reactome.org/PathwayBrowser/#/R-HSA-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks TAS Homo sapiens 145371 R-ALL-9657530 binimetinib [cytosol] R-MMU-5672973 https://reactome.org/PathwayBrowser/#/R-MMU-5672973 MAP2Ks phosphorylate MAPKs IEA Mus musculus 145371 R-ALL-9657530 binimetinib [cytosol] R-MMU-9657606 https://reactome.org/PathwayBrowser/#/R-MMU-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Mus musculus 145371 R-ALL-9657530 binimetinib [cytosol] R-RNO-5672973 https://reactome.org/PathwayBrowser/#/R-RNO-5672973 MAP2Ks phosphorylate MAPKs IEA Rattus norvegicus 145371 R-ALL-9657530 binimetinib [cytosol] R-RNO-9657606 https://reactome.org/PathwayBrowser/#/R-RNO-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Rattus norvegicus 145371 R-ALL-9657530 binimetinib [cytosol] R-SSC-5672973 https://reactome.org/PathwayBrowser/#/R-SSC-5672973 MAP2Ks phosphorylate MAPKs IEA Sus scrofa 145371 R-ALL-9657530 binimetinib [cytosol] R-SSC-9657606 https://reactome.org/PathwayBrowser/#/R-SSC-9657606 Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks IEA Sus scrofa 145372 R-ALL-9695700 gilteritinib [cytosol] R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 145372 R-ALL-9695700 gilteritinib [cytosol] R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 145372 R-ALL-9695700 gilteritinib [cytosol] R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 145372 R-ALL-9695700 gilteritinib [cytosol] R-HSA-9695828 https://reactome.org/PathwayBrowser/#/R-HSA-9695828 FLT3 binds type I TKI TAS Homo sapiens 145372 R-ALL-9695700 gilteritinib [cytosol] R-HSA-9702508 https://reactome.org/PathwayBrowser/#/R-HSA-9702508 FLT mutants bind type I TKIs TAS Homo sapiens 145372 R-ALL-9695700 gilteritinib [cytosol] R-HSA-9702589 https://reactome.org/PathwayBrowser/#/R-HSA-9702589 gilteritinib-resistant FLT3 mutants don't bind gilteritinib TAS Homo sapiens 145372 R-ALL-9695700 gilteritinib [cytosol] R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 145372 R-ALL-9695700 gilteritinib [cytosol] R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 145373 R-ALL-9677649 pexidartinib [cytosol] R-BTA-9604767 https://reactome.org/PathwayBrowser/#/R-BTA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Bos taurus 145373 R-ALL-9677649 pexidartinib [cytosol] R-CFA-9604767 https://reactome.org/PathwayBrowser/#/R-CFA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Canis familiaris 145373 R-ALL-9677649 pexidartinib [cytosol] R-HSA-9604767 https://reactome.org/PathwayBrowser/#/R-HSA-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates TAS Homo sapiens 145373 R-ALL-9677649 pexidartinib [cytosol] R-HSA-9695831 https://reactome.org/PathwayBrowser/#/R-HSA-9695831 FLT3 binds type II TKI TAS Homo sapiens 145373 R-ALL-9677649 pexidartinib [cytosol] R-HSA-9702510 https://reactome.org/PathwayBrowser/#/R-HSA-9702510 FLT mutants bind type II TKIs TAS Homo sapiens 145373 R-ALL-9677649 pexidartinib [cytosol] R-HSA-9702607 https://reactome.org/PathwayBrowser/#/R-HSA-9702607 pexidartinib-resistant FLT3 mutants don't bind pexidartinib TAS Homo sapiens 145373 R-ALL-9677649 pexidartinib [cytosol] R-MMU-9604767 https://reactome.org/PathwayBrowser/#/R-MMU-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Mus musculus 145373 R-ALL-9677649 pexidartinib [cytosol] R-SSC-9604767 https://reactome.org/PathwayBrowser/#/R-SSC-9604767 FLT3LG dimer:FLT3 dimer autophosphorylates IEA Sus scrofa 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 145694 R-ALL-9731298 8-oxo-GMP(2-) [cytosol] R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 14597 R-ALL-5696224 methylarsonite [cytosol] R-BTA-5696213 https://reactome.org/PathwayBrowser/#/R-BTA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Bos taurus 14597 R-ALL-5696224 methylarsonite [cytosol] R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 14597 R-ALL-5696224 methylarsonite [cytosol] R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 14597 R-ALL-5696224 methylarsonite [cytosol] R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 14597 R-ALL-5696224 methylarsonite [cytosol] R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 14597 R-ALL-5696224 methylarsonite [cytosol] R-DRE-5696213 https://reactome.org/PathwayBrowser/#/R-DRE-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Danio rerio 14597 R-ALL-5696224 methylarsonite [cytosol] R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 14597 R-ALL-5696224 methylarsonite [cytosol] R-GGA-5696213 https://reactome.org/PathwayBrowser/#/R-GGA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Gallus gallus 14597 R-ALL-5696224 methylarsonite [cytosol] R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 14597 R-ALL-5696224 methylarsonite [cytosol] R-HSA-5696213 https://reactome.org/PathwayBrowser/#/R-HSA-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite TAS Homo sapiens 14597 R-ALL-5696224 methylarsonite [cytosol] R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 14597 R-ALL-5696224 methylarsonite [cytosol] R-MMU-5696213 https://reactome.org/PathwayBrowser/#/R-MMU-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Mus musculus 14597 R-ALL-5696224 methylarsonite [cytosol] R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 14597 R-ALL-5696224 methylarsonite [cytosol] R-RNO-5696213 https://reactome.org/PathwayBrowser/#/R-RNO-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Rattus norvegicus 14597 R-ALL-5696224 methylarsonite [cytosol] R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 14597 R-ALL-5696224 methylarsonite [cytosol] R-SSC-5696213 https://reactome.org/PathwayBrowser/#/R-SSC-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Sus scrofa 14597 R-ALL-5696224 methylarsonite [cytosol] R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 14597 R-ALL-5696224 methylarsonite [cytosol] R-XTR-5696213 https://reactome.org/PathwayBrowser/#/R-XTR-5696213 AS3MT transfers CH3 from AdoMet to methylarsonite IEA Xenopus tropicalis 14597 R-ALL-5696224 methylarsonite [cytosol] R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9680262 https://reactome.org/PathwayBrowser/#/R-HSA-9680262 SARS coronavirus gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9681674 https://reactome.org/PathwayBrowser/#/R-HSA-9681674 nsp12 synthesizes minus strand SARS-CoV-1 genomic RNA complement TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9681840 https://reactome.org/PathwayBrowser/#/R-HSA-9681840 RTC synthesizes SARS-CoV-1 plus strand genomic RNA TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9682465 https://reactome.org/PathwayBrowser/#/R-HSA-9682465 RTC completes synthesis of the minus strand genomic RNA complement TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9682563 https://reactome.org/PathwayBrowser/#/R-HSA-9682563 nsp12 misincorporates a nucleotide in nascent RNA minus strand TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9687384 https://reactome.org/PathwayBrowser/#/R-HSA-9687384 SARS-CoV-1 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9687388 https://reactome.org/PathwayBrowser/#/R-HSA-9687388 SARS-CoV-1 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694419 https://reactome.org/PathwayBrowser/#/R-HSA-9694419 SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694541 https://reactome.org/PathwayBrowser/#/R-HSA-9694541 SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694549 https://reactome.org/PathwayBrowser/#/R-HSA-9694549 RTC completes synthesis of the minus strand genomic RNA complement IEA Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694581 https://reactome.org/PathwayBrowser/#/R-HSA-9694581 RTC synthesizes SARS-CoV-2 plus strand genomic RNA TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694605 https://reactome.org/PathwayBrowser/#/R-HSA-9694605 nsp12 synthesizes minus strand SARS-CoV-2 genomic RNA complement TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694665 https://reactome.org/PathwayBrowser/#/R-HSA-9694665 SARS-CoV-2 gRNA:RTC:nascent RNA minus strand binds RTC inhibitors TAS Homo sapiens 145994 R-ALL-9680278 remdesivir [double membrane vesicle viral factory outer membrane] R-HSA-9694792 https://reactome.org/PathwayBrowser/#/R-HSA-9694792 nsp12 misincorporates a nucleotide in nascent RNA minus strand IEA Homo sapiens 146219 R-ALL-9700775 efonidipine [extracellular region] R-BTA-9614031 https://reactome.org/PathwayBrowser/#/R-BTA-9614031 Class IV antihypertensives bind LTCC multimer IEA Bos taurus 146219 R-ALL-9700775 efonidipine [extracellular region] R-CEL-9614031 https://reactome.org/PathwayBrowser/#/R-CEL-9614031 Class IV antihypertensives bind LTCC multimer IEA Caenorhabditis elegans 146219 R-ALL-9700775 efonidipine [extracellular region] R-CFA-9614031 https://reactome.org/PathwayBrowser/#/R-CFA-9614031 Class IV antihypertensives bind LTCC multimer IEA Canis familiaris 146219 R-ALL-9700775 efonidipine [extracellular region] R-DME-9614031 https://reactome.org/PathwayBrowser/#/R-DME-9614031 Class IV antihypertensives bind LTCC multimer IEA Drosophila melanogaster 146219 R-ALL-9700775 efonidipine [extracellular region] R-GGA-9614031 https://reactome.org/PathwayBrowser/#/R-GGA-9614031 Class IV antihypertensives bind LTCC multimer IEA Gallus gallus 146219 R-ALL-9700775 efonidipine [extracellular region] R-HSA-9614031 https://reactome.org/PathwayBrowser/#/R-HSA-9614031 Class IV antihypertensives bind LTCC multimer TAS Homo sapiens 146219 R-ALL-9700775 efonidipine [extracellular region] R-MMU-9614031 https://reactome.org/PathwayBrowser/#/R-MMU-9614031 Class IV antihypertensives bind LTCC multimer IEA Mus musculus 146219 R-ALL-9700775 efonidipine [extracellular region] R-RNO-9614031 https://reactome.org/PathwayBrowser/#/R-RNO-9614031 Class IV antihypertensives bind LTCC multimer IEA Rattus norvegicus 146219 R-ALL-9700775 efonidipine [extracellular region] R-SSC-9614031 https://reactome.org/PathwayBrowser/#/R-SSC-9614031 Class IV antihypertensives bind LTCC multimer IEA Sus scrofa 146219 R-ALL-9700775 efonidipine [extracellular region] R-XTR-9614031 https://reactome.org/PathwayBrowser/#/R-XTR-9614031 Class IV antihypertensives bind LTCC multimer IEA Xenopus tropicalis 14649 R-ALL-8869353 NMN [cytosol] R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 14649 R-ALL-8869353 NMN [cytosol] R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 14649 R-ALL-8869353 NMN [cytosol] R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 14649 R-ALL-8940067 NMN [extracellular region] R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 14649 R-ALL-8940067 NMN [extracellular region] R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 14649 R-ALL-8869353 NMN [cytosol] R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 14649 R-ALL-8869353 NMN [cytosol] R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 14649 R-ALL-8869353 NMN [cytosol] R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 14649 R-ALL-8940067 NMN [extracellular region] R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 14649 R-ALL-8940067 NMN [extracellular region] R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 14649 R-ALL-8869353 NMN [cytosol] R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 14649 R-ALL-8869353 NMN [cytosol] R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 14649 R-ALL-8869353 NMN [cytosol] R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 14649 R-ALL-8869353 NMN [cytosol] R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 14649 R-ALL-8869353 NMN [cytosol] R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 14649 R-ALL-8869353 NMN [cytosol] R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 14649 R-ALL-8940067 NMN [extracellular region] R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 14649 R-ALL-8940067 NMN [extracellular region] R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 14649 R-ALL-8869353 NMN [cytosol] R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 14649 R-ALL-8869353 NMN [cytosol] R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 14649 R-ALL-8940067 NMN [extracellular region] R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 14649 R-ALL-8940067 NMN [extracellular region] R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 14649 R-ALL-8869353 NMN [cytosol] R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 14649 R-ALL-8869353 NMN [cytosol] R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 14649 R-ALL-8869353 NMN [cytosol] R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 14649 R-ALL-8940067 NMN [extracellular region] R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 14649 R-ALL-8940067 NMN [extracellular region] R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 14649 R-ALL-8869353 NMN [cytosol] R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 14649 R-ALL-8869353 NMN [cytosol] R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 14649 R-ALL-8869353 NMN [cytosol] R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 14649 R-ALL-8940067 NMN [extracellular region] R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 14649 R-ALL-8940067 NMN [extracellular region] R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 14649 R-ALL-8869353 NMN [cytosol] R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 14649 R-ALL-8869353 NMN [cytosol] R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 14649 R-ALL-8869353 NMN [cytosol] R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 14649 R-ALL-8940067 NMN [extracellular region] R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 14649 R-ALL-8940067 NMN [extracellular region] R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 14649 R-ALL-8869353 NMN [cytosol] R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 14649 R-ALL-8869353 NMN [cytosol] R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 14649 R-ALL-8940067 NMN [extracellular region] R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 14649 R-ALL-8940067 NMN [extracellular region] R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 14649 R-ALL-8869353 NMN [cytosol] R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 14649 R-ALL-8869353 NMN [cytosol] R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 14649 R-ALL-8869353 NMN [cytosol] R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 14649 R-ALL-8869353 NMN [cytosol] R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 14649 R-ALL-8869353 NMN [cytosol] R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 14649 R-ALL-8940067 NMN [extracellular region] R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 14649 R-ALL-8940067 NMN [extracellular region] R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 14649 R-ALL-8940067 NMN [extracellular region] R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 14649 R-ALL-8940067 NMN [extracellular region] R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-GGA-419145 https://reactome.org/PathwayBrowser/#/R-GGA-419145 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate TAS Gallus gallus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 147286 R-ALL-111354 N-Formyl-GAR [cytosol] R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 147287 R-ALL-111369 FGAM [cytosol] R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 147287 R-ALL-111369 FGAM [cytosol] R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 147287 R-ALL-111369 FGAM [cytosol] R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 147287 R-ALL-111369 FGAM [cytosol] R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 147287 R-ALL-111369 FGAM [cytosol] R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 147287 R-ALL-111369 FGAM [cytosol] R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 147287 R-ALL-111369 FGAM [cytosol] R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 147287 R-ALL-111369 FGAM [cytosol] R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 147287 R-ALL-111369 FGAM [cytosol] R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 147287 R-ALL-111369 FGAM [cytosol] R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 147287 R-ALL-111369 FGAM [cytosol] R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 147287 R-ALL-111369 FGAM [cytosol] R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 147287 R-ALL-111369 FGAM [cytosol] R-GGA-419157 https://reactome.org/PathwayBrowser/#/R-GGA-419157 5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate TAS Gallus gallus 147287 R-ALL-111369 FGAM [cytosol] R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 147287 R-ALL-111369 FGAM [cytosol] R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 147287 R-ALL-111369 FGAM [cytosol] R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 147287 R-ALL-111369 FGAM [cytosol] R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 147287 R-ALL-111369 FGAM [cytosol] R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 147287 R-ALL-111369 FGAM [cytosol] R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 147287 R-ALL-111369 FGAM [cytosol] R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 147287 R-ALL-111369 FGAM [cytosol] R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 147287 R-ALL-111369 FGAM [cytosol] R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 147287 R-ALL-111369 FGAM [cytosol] R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 147287 R-ALL-111369 FGAM [cytosol] R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 147287 R-ALL-111369 FGAM [cytosol] R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 147287 R-ALL-111369 FGAM [cytosol] R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 147287 R-ALL-111369 FGAM [cytosol] R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9681596 https://reactome.org/PathwayBrowser/#/R-HSA-9681596 3CLp dimer binds α-Ketoamides TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9694592 https://reactome.org/PathwayBrowser/#/R-HSA-9694592 3CLp dimer binds 3CLp inhibitors TAS Homo sapiens 147409 R-ALL-9682024 compound 13b [cytosol] R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 147411 R-ALL-9687653 GSK-3beta inhibitor I [cytosol] R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 147411 R-ALL-9687653 GSK-3beta inhibitor I [cytosol] R-HSA-9687724 https://reactome.org/PathwayBrowser/#/R-HSA-9687724 GSK3B binds GSKi TAS Homo sapiens 147411 R-ALL-9687653 GSK-3beta inhibitor I [cytosol] R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 149484 R-ALL-9683466 CQ2+ [endocytic vesicle lumen] R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-BTA-5693967 https://reactome.org/PathwayBrowser/#/R-BTA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Bos taurus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-BTA-5693977 https://reactome.org/PathwayBrowser/#/R-BTA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Bos taurus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-CEL-5693967 https://reactome.org/PathwayBrowser/#/R-CEL-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Caenorhabditis elegans 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-CEL-5693977 https://reactome.org/PathwayBrowser/#/R-CEL-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Caenorhabditis elegans 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-CFA-5693967 https://reactome.org/PathwayBrowser/#/R-CFA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Canis familiaris 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-CFA-5693977 https://reactome.org/PathwayBrowser/#/R-CFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Canis familiaris 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DDI-5693967 https://reactome.org/PathwayBrowser/#/R-DDI-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Dictyostelium discoideum 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DDI-5693977 https://reactome.org/PathwayBrowser/#/R-DDI-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Dictyostelium discoideum 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DME-5693967 https://reactome.org/PathwayBrowser/#/R-DME-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Drosophila melanogaster 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DME-5693977 https://reactome.org/PathwayBrowser/#/R-DME-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Drosophila melanogaster 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DRE-5693967 https://reactome.org/PathwayBrowser/#/R-DRE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Danio rerio 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-DRE-5693977 https://reactome.org/PathwayBrowser/#/R-DRE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Danio rerio 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-GGA-5693967 https://reactome.org/PathwayBrowser/#/R-GGA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Gallus gallus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-HSA-5693967 https://reactome.org/PathwayBrowser/#/R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly TAS Homo sapiens 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-HSA-5693977 https://reactome.org/PathwayBrowser/#/R-HSA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF TAS Homo sapiens 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-MMU-5693967 https://reactome.org/PathwayBrowser/#/R-MMU-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Mus musculus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-MMU-5693977 https://reactome.org/PathwayBrowser/#/R-MMU-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Mus musculus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-PFA-5693977 https://reactome.org/PathwayBrowser/#/R-PFA-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Plasmodium falciparum 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-RNO-5693977 https://reactome.org/PathwayBrowser/#/R-RNO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Rattus norvegicus 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SCE-5693967 https://reactome.org/PathwayBrowser/#/R-SCE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Saccharomyces cerevisiae 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SCE-5693977 https://reactome.org/PathwayBrowser/#/R-SCE-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Saccharomyces cerevisiae 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SPO-5693967 https://reactome.org/PathwayBrowser/#/R-SPO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Schizosaccharomyces pombe 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SPO-5693977 https://reactome.org/PathwayBrowser/#/R-SPO-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Schizosaccharomyces pombe 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SSC-5693967 https://reactome.org/PathwayBrowser/#/R-SSC-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Sus scrofa 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-SSC-5693977 https://reactome.org/PathwayBrowser/#/R-SSC-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Sus scrofa 14949 R-ALL-5693962 SAMDLL [mitochondrial matrix] R-XTR-5693977 https://reactome.org/PathwayBrowser/#/R-XTR-5693977 AMT transfers NH2CH2 from GCSH:SAMDLL to THF IEA Xenopus tropicalis 149564 R-ALL-9685630 HCQ2+ [endocytic vesicle lumen] R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 149601 R-ALL-9734538 bempedoic acid [cytosol] R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-BTA-9734535 https://reactome.org/PathwayBrowser/#/R-BTA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Bos taurus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-BTA-9734540 https://reactome.org/PathwayBrowser/#/R-BTA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Bos taurus 149601 R-ALL-9734538 bempedoic acid [cytosol] R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-CEL-9734535 https://reactome.org/PathwayBrowser/#/R-CEL-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Caenorhabditis elegans 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-CEL-9734540 https://reactome.org/PathwayBrowser/#/R-CEL-9734540 ACLY tetramer binds ETC-1002-CoA IEA Caenorhabditis elegans 149601 R-ALL-9734538 bempedoic acid [cytosol] R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-CFA-9734535 https://reactome.org/PathwayBrowser/#/R-CFA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Canis familiaris 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-CFA-9734540 https://reactome.org/PathwayBrowser/#/R-CFA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Canis familiaris 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-DDI-9734540 https://reactome.org/PathwayBrowser/#/R-DDI-9734540 ACLY tetramer binds ETC-1002-CoA IEA Dictyostelium discoideum 149601 R-ALL-9734538 bempedoic acid [cytosol] R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-DME-9734535 https://reactome.org/PathwayBrowser/#/R-DME-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Drosophila melanogaster 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-DME-9734540 https://reactome.org/PathwayBrowser/#/R-DME-9734540 ACLY tetramer binds ETC-1002-CoA IEA Drosophila melanogaster 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-DRE-9734540 https://reactome.org/PathwayBrowser/#/R-DRE-9734540 ACLY tetramer binds ETC-1002-CoA IEA Danio rerio 149601 R-ALL-9734538 bempedoic acid [cytosol] R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-GGA-9734535 https://reactome.org/PathwayBrowser/#/R-GGA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Gallus gallus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-GGA-9734540 https://reactome.org/PathwayBrowser/#/R-GGA-9734540 ACLY tetramer binds ETC-1002-CoA IEA Gallus gallus 149601 R-ALL-9734538 bempedoic acid [cytosol] R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-HSA-9734535 https://reactome.org/PathwayBrowser/#/R-HSA-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA TAS Homo sapiens 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-HSA-9734540 https://reactome.org/PathwayBrowser/#/R-HSA-9734540 ACLY tetramer binds ETC-1002-CoA TAS Homo sapiens 149601 R-ALL-9734538 bempedoic acid [cytosol] R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-MMU-9734535 https://reactome.org/PathwayBrowser/#/R-MMU-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Mus musculus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-MMU-9734540 https://reactome.org/PathwayBrowser/#/R-MMU-9734540 ACLY tetramer binds ETC-1002-CoA IEA Mus musculus 149601 R-ALL-9734538 bempedoic acid [cytosol] R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-RNO-9734535 https://reactome.org/PathwayBrowser/#/R-RNO-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Rattus norvegicus 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-RNO-9734540 https://reactome.org/PathwayBrowser/#/R-RNO-9734540 ACLY tetramer binds ETC-1002-CoA IEA Rattus norvegicus 149601 R-ALL-9734538 bempedoic acid [cytosol] R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-SCE-9734535 https://reactome.org/PathwayBrowser/#/R-SCE-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Saccharomyces cerevisiae 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-SPO-9734540 https://reactome.org/PathwayBrowser/#/R-SPO-9734540 ACLY tetramer binds ETC-1002-CoA IEA Schizosaccharomyces pombe 149601 R-ALL-9734538 bempedoic acid [cytosol] R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-SSC-9734535 https://reactome.org/PathwayBrowser/#/R-SSC-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Sus scrofa 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-SSC-9734540 https://reactome.org/PathwayBrowser/#/R-SSC-9734540 ACLY tetramer binds ETC-1002-CoA IEA Sus scrofa 149601 R-ALL-9734538 bempedoic acid [cytosol] R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-XTR-9734535 https://reactome.org/PathwayBrowser/#/R-XTR-9734535 SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA IEA Xenopus tropicalis 149601 R-ALL-9734541 ETC-1002-CoA [cytosol] R-XTR-9734540 https://reactome.org/PathwayBrowser/#/R-XTR-9734540 ACLY tetramer binds ETC-1002-CoA IEA Xenopus tropicalis 15075 R-ALL-5357662 selenate [cytosol] R-HSA-2408525 https://reactome.org/PathwayBrowser/#/R-HSA-2408525 H2SeO4 is converted to APSe by PAPSS1,2 IEA Homo sapiens 15075 R-ALL-5357662 selenate [cytosol] R-RNO-2408504 https://reactome.org/PathwayBrowser/#/R-RNO-2408504 H2SeO4 is converted to APSe by PAPSS1,2 TAS Rattus norvegicus 15138 R-ALL-936697 S(2-) [cytosol] R-MTU-936590 https://reactome.org/PathwayBrowser/#/R-MTU-936590 sulfur transfer to carrier protein TAS Mycobacterium tuberculosis 15138 R-ALL-936697 S(2-) [cytosol] R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 15138 R-ALL-936697 S(2-) [cytosol] R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15138 R-ALL-936697 S(2-) [cytosol] R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 15266 R-ALL-1475054 PPP [cytosol] R-BTA-1474184 https://reactome.org/PathwayBrowser/#/R-BTA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Bos taurus 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 15266 R-ALL-1475054 PPP [cytosol] R-CEL-1474184 https://reactome.org/PathwayBrowser/#/R-CEL-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Caenorhabditis elegans 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 15266 R-ALL-1475054 PPP [cytosol] R-DDI-1474184 https://reactome.org/PathwayBrowser/#/R-DDI-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Dictyostelium discoideum 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 15266 R-ALL-1475054 PPP [cytosol] R-DME-1474184 https://reactome.org/PathwayBrowser/#/R-DME-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Drosophila melanogaster 15266 R-ALL-1475054 PPP [cytosol] R-DRE-1474184 https://reactome.org/PathwayBrowser/#/R-DRE-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Danio rerio 15266 R-ALL-1475054 PPP [cytosol] R-GGA-1474184 https://reactome.org/PathwayBrowser/#/R-GGA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Gallus gallus 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 15266 R-ALL-1475054 PPP [cytosol] R-HSA-1474184 https://reactome.org/PathwayBrowser/#/R-HSA-1474184 DHNTP is dephosphorylated by PTPS to PTHP TAS Homo sapiens 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 15266 R-ALL-1475054 PPP [cytosol] R-MMU-1474184 https://reactome.org/PathwayBrowser/#/R-MMU-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Mus musculus 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 15266 R-ALL-1475054 PPP [cytosol] R-PFA-1474184 https://reactome.org/PathwayBrowser/#/R-PFA-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Plasmodium falciparum 15266 R-ALL-1475054 PPP [cytosol] R-RNO-1474184 https://reactome.org/PathwayBrowser/#/R-RNO-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Rattus norvegicus 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 15266 R-ALL-1475054 PPP [cytosol] R-SSC-1474184 https://reactome.org/PathwayBrowser/#/R-SSC-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Sus scrofa 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 15266 R-ALL-1475054 PPP [cytosol] R-XTR-1474184 https://reactome.org/PathwayBrowser/#/R-XTR-1474184 DHNTP is dephosphorylated by PTPS to PTHP IEA Xenopus tropicalis 15266 R-ALL-3159274 PPP [mitochondrial matrix] R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15343 R-ALL-29510 CH3CHO [cytosol] R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15343 R-ALL-29510 CH3CHO [cytosol] R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 15343 R-ALL-29510 CH3CHO [cytosol] R-BTA-6787321 https://reactome.org/PathwayBrowser/#/R-BTA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Bos taurus 15343 R-ALL-29510 CH3CHO [cytosol] R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15343 R-ALL-29510 CH3CHO [cytosol] R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 15343 R-ALL-29510 CH3CHO [cytosol] R-CEL-6787321 https://reactome.org/PathwayBrowser/#/R-CEL-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Caenorhabditis elegans 15343 R-ALL-29510 CH3CHO [cytosol] R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15343 R-ALL-29510 CH3CHO [cytosol] R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15343 R-ALL-29510 CH3CHO [cytosol] R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15343 R-ALL-29510 CH3CHO [cytosol] R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 15343 R-ALL-29510 CH3CHO [cytosol] R-CFA-6787321 https://reactome.org/PathwayBrowser/#/R-CFA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Canis familiaris 15343 R-ALL-29510 CH3CHO [cytosol] R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15343 R-ALL-29510 CH3CHO [cytosol] R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15343 R-ALL-29510 CH3CHO [cytosol] R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15343 R-ALL-29510 CH3CHO [cytosol] R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 15343 R-ALL-29510 CH3CHO [cytosol] R-DME-6787321 https://reactome.org/PathwayBrowser/#/R-DME-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Drosophila melanogaster 15343 R-ALL-29510 CH3CHO [cytosol] R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15343 R-ALL-29510 CH3CHO [cytosol] R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15343 R-ALL-29510 CH3CHO [cytosol] R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15343 R-ALL-29510 CH3CHO [cytosol] R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 15343 R-ALL-29510 CH3CHO [cytosol] R-DRE-6787321 https://reactome.org/PathwayBrowser/#/R-DRE-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Danio rerio 15343 R-ALL-29510 CH3CHO [cytosol] R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15343 R-ALL-29510 CH3CHO [cytosol] R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15343 R-ALL-29510 CH3CHO [cytosol] R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15343 R-ALL-113681 CH3CHO [nucleoplasm] R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 15343 R-ALL-29510 CH3CHO [cytosol] R-GGA-6787321 https://reactome.org/PathwayBrowser/#/R-GGA-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Gallus gallus 15343 R-ALL-29510 CH3CHO [cytosol] R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15343 R-ALL-29510 CH3CHO [cytosol] R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15343 R-ALL-113681 CH3CHO [nucleoplasm] R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 15343 R-ALL-113681 CH3CHO [nucleoplasm] R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-449872 https://reactome.org/PathwayBrowser/#/R-HSA-449872 acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] TAS Homo sapiens 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-HSA-449872 https://reactome.org/PathwayBrowser/#/R-HSA-449872 acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] TAS Homo sapiens 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-6787321 https://reactome.org/PathwayBrowser/#/R-HSA-6787321 DERA cleaves dR5P to GA3P and CH3CHO TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15343 R-ALL-29510 CH3CHO [cytosol] R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15343 R-ALL-29510 CH3CHO [cytosol] R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15343 R-ALL-29510 CH3CHO [cytosol] R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 15343 R-ALL-29510 CH3CHO [cytosol] R-MMU-6787321 https://reactome.org/PathwayBrowser/#/R-MMU-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Mus musculus 15343 R-ALL-29510 CH3CHO [cytosol] R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15343 R-ALL-29510 CH3CHO [cytosol] R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15343 R-ALL-29510 CH3CHO [cytosol] R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15343 R-ALL-29510 CH3CHO [cytosol] R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 15343 R-ALL-29510 CH3CHO [cytosol] R-RNO-6787321 https://reactome.org/PathwayBrowser/#/R-RNO-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Rattus norvegicus 15343 R-ALL-29510 CH3CHO [cytosol] R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15343 R-ALL-29510 CH3CHO [cytosol] R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15343 R-ALL-29510 CH3CHO [cytosol] R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15343 R-ALL-29510 CH3CHO [cytosol] R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15343 R-ALL-29510 CH3CHO [cytosol] R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15343 R-ALL-29510 CH3CHO [cytosol] R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15343 R-ALL-29510 CH3CHO [cytosol] R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15343 R-ALL-29510 CH3CHO [cytosol] R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 15343 R-ALL-29510 CH3CHO [cytosol] R-SSC-6787321 https://reactome.org/PathwayBrowser/#/R-SSC-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Sus scrofa 15343 R-ALL-29510 CH3CHO [cytosol] R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15343 R-ALL-29510 CH3CHO [cytosol] R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15343 R-ALL-113745 CH3CHO [endoplasmic reticulum lumen] R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15343 R-ALL-29510 CH3CHO [cytosol] R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15343 R-ALL-29510 CH3CHO [cytosol] R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 15343 R-ALL-29510 CH3CHO [cytosol] R-XTR-6787321 https://reactome.org/PathwayBrowser/#/R-XTR-6787321 DERA cleaves dR5P to GA3P and CH3CHO IEA Xenopus tropicalis 15343 R-ALL-29510 CH3CHO [cytosol] R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15343 R-ALL-29510 CH3CHO [cytosol] R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 15343 R-ALL-113532 CH3CHO [mitochondrial matrix] R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15344 R-ALL-433680 ACA [extracellular region] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-BTA-74177 https://reactome.org/PathwayBrowser/#/R-BTA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Bos taurus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-BTA-74180 https://reactome.org/PathwayBrowser/#/R-BTA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Bos taurus 15344 R-ALL-433680 ACA [extracellular region] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15344 R-ALL-433680 ACA [extracellular region] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CEL-74177 https://reactome.org/PathwayBrowser/#/R-CEL-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Caenorhabditis elegans 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CEL-74180 https://reactome.org/PathwayBrowser/#/R-CEL-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Caenorhabditis elegans 15344 R-ALL-433680 ACA [extracellular region] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15344 R-ALL-433680 ACA [extracellular region] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CFA-74177 https://reactome.org/PathwayBrowser/#/R-CFA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Canis familiaris 15344 R-ALL-73909 ACA [mitochondrial matrix] R-CFA-74180 https://reactome.org/PathwayBrowser/#/R-CFA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Canis familiaris 15344 R-ALL-433680 ACA [extracellular region] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DDI-74177 https://reactome.org/PathwayBrowser/#/R-DDI-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Dictyostelium discoideum 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DDI-74180 https://reactome.org/PathwayBrowser/#/R-DDI-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Dictyostelium discoideum 15344 R-ALL-433680 ACA [extracellular region] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DME-74177 https://reactome.org/PathwayBrowser/#/R-DME-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Drosophila melanogaster 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DME-74180 https://reactome.org/PathwayBrowser/#/R-DME-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Drosophila melanogaster 15344 R-ALL-433680 ACA [extracellular region] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15344 R-ALL-433680 ACA [extracellular region] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DRE-74177 https://reactome.org/PathwayBrowser/#/R-DRE-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Danio rerio 15344 R-ALL-73909 ACA [mitochondrial matrix] R-DRE-74180 https://reactome.org/PathwayBrowser/#/R-DRE-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Danio rerio 15344 R-ALL-433680 ACA [extracellular region] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-GGA-74177 https://reactome.org/PathwayBrowser/#/R-GGA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Gallus gallus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-GGA-74180 https://reactome.org/PathwayBrowser/#/R-GGA-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Gallus gallus 15344 R-ALL-433680 ACA [extracellular region] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15344 R-ALL-433680 ACA [extracellular region] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-ALL-433680 ACA [extracellular region] R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-ALL-73909 ACA [mitochondrial matrix] R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 15344 R-ALL-73909 ACA [mitochondrial matrix] R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 15344 R-ALL-73909 ACA [mitochondrial matrix] R-HSA-74177 https://reactome.org/PathwayBrowser/#/R-HSA-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA TAS Homo sapiens 15344 R-ALL-73909 ACA [mitochondrial matrix] R-HSA-74180 https://reactome.org/PathwayBrowser/#/R-HSA-74180 HMG CoA => acetoacetic acid + acetyl CoA TAS Homo sapiens 15344 R-ALL-433680 ACA [extracellular region] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15344 R-ALL-433680 ACA [extracellular region] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-MMU-74177 https://reactome.org/PathwayBrowser/#/R-MMU-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Mus musculus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-MMU-74180 https://reactome.org/PathwayBrowser/#/R-MMU-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Mus musculus 15344 R-ALL-433680 ACA [extracellular region] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15344 R-ALL-433680 ACA [extracellular region] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-RNO-74177 https://reactome.org/PathwayBrowser/#/R-RNO-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Rattus norvegicus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-RNO-74180 https://reactome.org/PathwayBrowser/#/R-RNO-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Rattus norvegicus 15344 R-ALL-433680 ACA [extracellular region] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 15344 R-ALL-433680 ACA [extracellular region] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SSC-74177 https://reactome.org/PathwayBrowser/#/R-SSC-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Sus scrofa 15344 R-ALL-73909 ACA [mitochondrial matrix] R-SSC-74180 https://reactome.org/PathwayBrowser/#/R-SSC-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Sus scrofa 15344 R-ALL-433680 ACA [extracellular region] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15344 R-ALL-73909 ACA [mitochondrial matrix] R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 15344 R-ALL-73909 ACA [mitochondrial matrix] R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 15344 R-ALL-73909 ACA [mitochondrial matrix] R-XTR-74177 https://reactome.org/PathwayBrowser/#/R-XTR-74177 OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA IEA Xenopus tropicalis 15344 R-ALL-73909 ACA [mitochondrial matrix] R-XTR-74180 https://reactome.org/PathwayBrowser/#/R-XTR-74180 HMG CoA => acetoacetic acid + acetyl CoA IEA Xenopus tropicalis 15344 R-ALL-433680 ACA [extracellular region] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-BTA-1483004 https://reactome.org/PathwayBrowser/#/R-BTA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-1483186 https://reactome.org/PathwayBrowser/#/R-BTA-1483186 PC is converted to PS by PTDSS1 IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-429594 https://reactome.org/PathwayBrowser/#/R-BTA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-444433 https://reactome.org/PathwayBrowser/#/R-BTA-444433 Cho transports from the extracellular space to the cytosol IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-444433 https://reactome.org/PathwayBrowser/#/R-BTA-444433 Cho transports from the extracellular space to the cytosol IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-549129 https://reactome.org/PathwayBrowser/#/R-BTA-549129 OCT1 transports organic cations into hepatic cells IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-549279 https://reactome.org/PathwayBrowser/#/R-BTA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-549322 https://reactome.org/PathwayBrowser/#/R-BTA-549322 OCT1 transports organic cations out of hepatic cells IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 15354 R-ALL-264638 Cho [extracellular region] R-BTA-561054 https://reactome.org/PathwayBrowser/#/R-BTA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-BTA-6797956 https://reactome.org/PathwayBrowser/#/R-BTA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Bos taurus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-BTA-6797956 https://reactome.org/PathwayBrowser/#/R-BTA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Bos taurus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-BTA-6797961 https://reactome.org/PathwayBrowser/#/R-BTA-6797961 CHDH oxidises Cho to BETALD IEA Bos taurus 15354 R-ALL-264618 Cho [cytosol] R-CEL-1483004 https://reactome.org/PathwayBrowser/#/R-CEL-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-1483186 https://reactome.org/PathwayBrowser/#/R-CEL-1483186 PC is converted to PS by PTDSS1 IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-429594 https://reactome.org/PathwayBrowser/#/R-CEL-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-444433 https://reactome.org/PathwayBrowser/#/R-CEL-444433 Cho transports from the extracellular space to the cytosol IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-444433 https://reactome.org/PathwayBrowser/#/R-CEL-444433 Cho transports from the extracellular space to the cytosol IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-549129 https://reactome.org/PathwayBrowser/#/R-CEL-549129 OCT1 transports organic cations into hepatic cells IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-549279 https://reactome.org/PathwayBrowser/#/R-CEL-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-549322 https://reactome.org/PathwayBrowser/#/R-CEL-549322 OCT1 transports organic cations out of hepatic cells IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-ALL-264638 Cho [extracellular region] R-CEL-561054 https://reactome.org/PathwayBrowser/#/R-CEL-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Caenorhabditis elegans 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-CEL-6797961 https://reactome.org/PathwayBrowser/#/R-CEL-6797961 CHDH oxidises Cho to BETALD IEA Caenorhabditis elegans 15354 R-ALL-264618 Cho [cytosol] R-CFA-1483004 https://reactome.org/PathwayBrowser/#/R-CFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-1483186 https://reactome.org/PathwayBrowser/#/R-CFA-1483186 PC is converted to PS by PTDSS1 IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-429594 https://reactome.org/PathwayBrowser/#/R-CFA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-444433 https://reactome.org/PathwayBrowser/#/R-CFA-444433 Cho transports from the extracellular space to the cytosol IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-444433 https://reactome.org/PathwayBrowser/#/R-CFA-444433 Cho transports from the extracellular space to the cytosol IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-549129 https://reactome.org/PathwayBrowser/#/R-CFA-549129 OCT1 transports organic cations into hepatic cells IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-549279 https://reactome.org/PathwayBrowser/#/R-CFA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-549322 https://reactome.org/PathwayBrowser/#/R-CFA-549322 OCT1 transports organic cations out of hepatic cells IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 15354 R-ALL-264638 Cho [extracellular region] R-CFA-561054 https://reactome.org/PathwayBrowser/#/R-CFA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-CFA-6797956 https://reactome.org/PathwayBrowser/#/R-CFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Canis familiaris 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-CFA-6797956 https://reactome.org/PathwayBrowser/#/R-CFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Canis familiaris 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-CFA-6797961 https://reactome.org/PathwayBrowser/#/R-CFA-6797961 CHDH oxidises Cho to BETALD IEA Canis familiaris 15354 R-ALL-264618 Cho [cytosol] R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 15354 R-ALL-264618 Cho [cytosol] R-DDI-1483186 https://reactome.org/PathwayBrowser/#/R-DDI-1483186 PC is converted to PS by PTDSS1 IEA Dictyostelium discoideum 15354 R-ALL-264618 Cho [cytosol] R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 15354 R-ALL-264638 Cho [extracellular region] R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15354 R-ALL-264618 Cho [cytosol] R-DDI-444433 https://reactome.org/PathwayBrowser/#/R-DDI-444433 Cho transports from the extracellular space to the cytosol IEA Dictyostelium discoideum 15354 R-ALL-264638 Cho [extracellular region] R-DDI-444433 https://reactome.org/PathwayBrowser/#/R-DDI-444433 Cho transports from the extracellular space to the cytosol IEA Dictyostelium discoideum 15354 R-ALL-264618 Cho [cytosol] R-DDI-6797956 https://reactome.org/PathwayBrowser/#/R-DDI-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-DDI-6797956 https://reactome.org/PathwayBrowser/#/R-DDI-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Dictyostelium discoideum 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-DDI-6797961 https://reactome.org/PathwayBrowser/#/R-DDI-6797961 CHDH oxidises Cho to BETALD IEA Dictyostelium discoideum 15354 R-ALL-264618 Cho [cytosol] R-DME-1483004 https://reactome.org/PathwayBrowser/#/R-DME-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-1483186 https://reactome.org/PathwayBrowser/#/R-DME-1483186 PC is converted to PS by PTDSS1 IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-429594 https://reactome.org/PathwayBrowser/#/R-DME-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-444433 https://reactome.org/PathwayBrowser/#/R-DME-444433 Cho transports from the extracellular space to the cytosol IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-444433 https://reactome.org/PathwayBrowser/#/R-DME-444433 Cho transports from the extracellular space to the cytosol IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-549129 https://reactome.org/PathwayBrowser/#/R-DME-549129 OCT1 transports organic cations into hepatic cells IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-549279 https://reactome.org/PathwayBrowser/#/R-DME-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-549322 https://reactome.org/PathwayBrowser/#/R-DME-549322 OCT1 transports organic cations out of hepatic cells IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 15354 R-ALL-264638 Cho [extracellular region] R-DME-561054 https://reactome.org/PathwayBrowser/#/R-DME-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DME-6797956 https://reactome.org/PathwayBrowser/#/R-DME-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Drosophila melanogaster 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-DME-6797956 https://reactome.org/PathwayBrowser/#/R-DME-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Drosophila melanogaster 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-DME-6797961 https://reactome.org/PathwayBrowser/#/R-DME-6797961 CHDH oxidises Cho to BETALD IEA Drosophila melanogaster 15354 R-ALL-264618 Cho [cytosol] R-DRE-1483004 https://reactome.org/PathwayBrowser/#/R-DRE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-1483186 https://reactome.org/PathwayBrowser/#/R-DRE-1483186 PC is converted to PS by PTDSS1 IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-444433 https://reactome.org/PathwayBrowser/#/R-DRE-444433 Cho transports from the extracellular space to the cytosol IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-444433 https://reactome.org/PathwayBrowser/#/R-DRE-444433 Cho transports from the extracellular space to the cytosol IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-549129 https://reactome.org/PathwayBrowser/#/R-DRE-549129 OCT1 transports organic cations into hepatic cells IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-549279 https://reactome.org/PathwayBrowser/#/R-DRE-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-549322 https://reactome.org/PathwayBrowser/#/R-DRE-549322 OCT1 transports organic cations out of hepatic cells IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 15354 R-ALL-264638 Cho [extracellular region] R-DRE-561054 https://reactome.org/PathwayBrowser/#/R-DRE-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Danio rerio 15354 R-ALL-264618 Cho [cytosol] R-GGA-1483004 https://reactome.org/PathwayBrowser/#/R-GGA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-1483186 https://reactome.org/PathwayBrowser/#/R-GGA-1483186 PC is converted to PS by PTDSS1 IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-429594 https://reactome.org/PathwayBrowser/#/R-GGA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-444433 https://reactome.org/PathwayBrowser/#/R-GGA-444433 Cho transports from the extracellular space to the cytosol IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-444433 https://reactome.org/PathwayBrowser/#/R-GGA-444433 Cho transports from the extracellular space to the cytosol IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-549129 https://reactome.org/PathwayBrowser/#/R-GGA-549129 OCT1 transports organic cations into hepatic cells IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-549279 https://reactome.org/PathwayBrowser/#/R-GGA-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-549322 https://reactome.org/PathwayBrowser/#/R-GGA-549322 OCT1 transports organic cations out of hepatic cells IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 15354 R-ALL-264638 Cho [extracellular region] R-GGA-561054 https://reactome.org/PathwayBrowser/#/R-GGA-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-GGA-6797956 https://reactome.org/PathwayBrowser/#/R-GGA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Gallus gallus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-GGA-6797956 https://reactome.org/PathwayBrowser/#/R-GGA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Gallus gallus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-GGA-6797961 https://reactome.org/PathwayBrowser/#/R-GGA-6797961 CHDH oxidises Cho to BETALD IEA Gallus gallus 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483004 https://reactome.org/PathwayBrowser/#/R-HSA-1483004 Cho is phosphorylated to PCho by CHK dimer TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483142 https://reactome.org/PathwayBrowser/#/R-HSA-1483142 PC is transphosphatidylated to PG by PLD1-4/6 IEA Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-1483186 https://reactome.org/PathwayBrowser/#/R-HSA-1483186 PC is converted to PS by PTDSS1 TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-429594 https://reactome.org/PathwayBrowser/#/R-HSA-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-444433 https://reactome.org/PathwayBrowser/#/R-HSA-444433 Cho transports from the extracellular space to the cytosol TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-444433 https://reactome.org/PathwayBrowser/#/R-HSA-444433 Cho transports from the extracellular space to the cytosol TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-549129 https://reactome.org/PathwayBrowser/#/R-HSA-549129 OCT1 transports organic cations into hepatic cells TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-549279 https://reactome.org/PathwayBrowser/#/R-HSA-549279 OCT2 mediates tubular uptake of organic cations in the kidney TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-549322 https://reactome.org/PathwayBrowser/#/R-HSA-549322 OCT1 transports organic cations out of hepatic cells TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-561054 https://reactome.org/PathwayBrowser/#/R-HSA-561054 OCT2 mediates tubular secretion of organic cations in the kidney TAS Homo sapiens 15354 R-ALL-264638 Cho [extracellular region] R-HSA-5658483 https://reactome.org/PathwayBrowser/#/R-HSA-5658483 Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-6797956 https://reactome.org/PathwayBrowser/#/R-HSA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix TAS Homo sapiens 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-HSA-6797956 https://reactome.org/PathwayBrowser/#/R-HSA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix TAS Homo sapiens 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-HSA-6797961 https://reactome.org/PathwayBrowser/#/R-HSA-6797961 CHDH oxidises Cho to BETALD TAS Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483004 https://reactome.org/PathwayBrowser/#/R-MMU-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483172 https://reactome.org/PathwayBrowser/#/R-MMU-1483172 PC is transphosphatidylated to PG by Pld1-4/6 TAS Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-1483186 https://reactome.org/PathwayBrowser/#/R-MMU-1483186 PC is converted to PS by PTDSS1 IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-429594 https://reactome.org/PathwayBrowser/#/R-MMU-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-444433 https://reactome.org/PathwayBrowser/#/R-MMU-444433 Cho transports from the extracellular space to the cytosol IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-444433 https://reactome.org/PathwayBrowser/#/R-MMU-444433 Cho transports from the extracellular space to the cytosol IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-549129 https://reactome.org/PathwayBrowser/#/R-MMU-549129 OCT1 transports organic cations into hepatic cells IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-549279 https://reactome.org/PathwayBrowser/#/R-MMU-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-549322 https://reactome.org/PathwayBrowser/#/R-MMU-549322 OCT1 transports organic cations out of hepatic cells IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 15354 R-ALL-264638 Cho [extracellular region] R-MMU-561054 https://reactome.org/PathwayBrowser/#/R-MMU-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-6797956 https://reactome.org/PathwayBrowser/#/R-MMU-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Mus musculus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-MMU-6797956 https://reactome.org/PathwayBrowser/#/R-MMU-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Mus musculus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-MMU-6797961 https://reactome.org/PathwayBrowser/#/R-MMU-6797961 CHDH oxidises Cho to BETALD IEA Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 15354 R-ALL-264618 Cho [cytosol] R-PFA-1483004 https://reactome.org/PathwayBrowser/#/R-PFA-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Plasmodium falciparum 15354 R-ALL-264618 Cho [cytosol] R-PFA-1483186 https://reactome.org/PathwayBrowser/#/R-PFA-1483186 PC is converted to PS by PTDSS1 IEA Plasmodium falciparum 15354 R-ALL-264618 Cho [cytosol] R-PFA-444433 https://reactome.org/PathwayBrowser/#/R-PFA-444433 Cho transports from the extracellular space to the cytosol IEA Plasmodium falciparum 15354 R-ALL-264638 Cho [extracellular region] R-PFA-444433 https://reactome.org/PathwayBrowser/#/R-PFA-444433 Cho transports from the extracellular space to the cytosol IEA Plasmodium falciparum 15354 R-ALL-264618 Cho [cytosol] R-PFA-6797956 https://reactome.org/PathwayBrowser/#/R-PFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Plasmodium falciparum 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-PFA-6797956 https://reactome.org/PathwayBrowser/#/R-PFA-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Plasmodium falciparum 15354 R-ALL-264618 Cho [cytosol] R-RNO-1483004 https://reactome.org/PathwayBrowser/#/R-RNO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-1483186 https://reactome.org/PathwayBrowser/#/R-RNO-1483186 PC is converted to PS by PTDSS1 IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-429594 https://reactome.org/PathwayBrowser/#/R-RNO-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-444433 https://reactome.org/PathwayBrowser/#/R-RNO-444433 Cho transports from the extracellular space to the cytosol IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-444433 https://reactome.org/PathwayBrowser/#/R-RNO-444433 Cho transports from the extracellular space to the cytosol IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-549129 https://reactome.org/PathwayBrowser/#/R-RNO-549129 OCT1 transports organic cations into hepatic cells IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-549279 https://reactome.org/PathwayBrowser/#/R-RNO-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-549322 https://reactome.org/PathwayBrowser/#/R-RNO-549322 OCT1 transports organic cations out of hepatic cells IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 15354 R-ALL-264638 Cho [extracellular region] R-RNO-561054 https://reactome.org/PathwayBrowser/#/R-RNO-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-RNO-6797956 https://reactome.org/PathwayBrowser/#/R-RNO-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Rattus norvegicus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-RNO-6797956 https://reactome.org/PathwayBrowser/#/R-RNO-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Rattus norvegicus 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-RNO-6797961 https://reactome.org/PathwayBrowser/#/R-RNO-6797961 CHDH oxidises Cho to BETALD IEA Rattus norvegicus 15354 R-ALL-264618 Cho [cytosol] R-SCE-1483004 https://reactome.org/PathwayBrowser/#/R-SCE-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Saccharomyces cerevisiae 15354 R-ALL-264618 Cho [cytosol] R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 15354 R-ALL-264618 Cho [cytosol] R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 15354 R-ALL-264618 Cho [cytosol] R-SPO-1483004 https://reactome.org/PathwayBrowser/#/R-SPO-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Schizosaccharomyces pombe 15354 R-ALL-264618 Cho [cytosol] R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 15354 R-ALL-264618 Cho [cytosol] R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 15354 R-ALL-264618 Cho [cytosol] R-SSC-1483004 https://reactome.org/PathwayBrowser/#/R-SSC-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-1483186 https://reactome.org/PathwayBrowser/#/R-SSC-1483186 PC is converted to PS by PTDSS1 IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-429594 https://reactome.org/PathwayBrowser/#/R-SSC-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-444433 https://reactome.org/PathwayBrowser/#/R-SSC-444433 Cho transports from the extracellular space to the cytosol IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-444433 https://reactome.org/PathwayBrowser/#/R-SSC-444433 Cho transports from the extracellular space to the cytosol IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-549129 https://reactome.org/PathwayBrowser/#/R-SSC-549129 OCT1 transports organic cations into hepatic cells IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-549279 https://reactome.org/PathwayBrowser/#/R-SSC-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-549322 https://reactome.org/PathwayBrowser/#/R-SSC-549322 OCT1 transports organic cations out of hepatic cells IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 15354 R-ALL-264638 Cho [extracellular region] R-SSC-561054 https://reactome.org/PathwayBrowser/#/R-SSC-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-SSC-6797956 https://reactome.org/PathwayBrowser/#/R-SSC-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Sus scrofa 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-SSC-6797956 https://reactome.org/PathwayBrowser/#/R-SSC-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Sus scrofa 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-SSC-6797961 https://reactome.org/PathwayBrowser/#/R-SSC-6797961 CHDH oxidises Cho to BETALD IEA Sus scrofa 15354 R-ALL-264618 Cho [cytosol] R-XTR-1483004 https://reactome.org/PathwayBrowser/#/R-XTR-1483004 Cho is phosphorylated to PCho by CHK dimer IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-1483186 https://reactome.org/PathwayBrowser/#/R-XTR-1483186 PC is converted to PS by PTDSS1 IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-429594 https://reactome.org/PathwayBrowser/#/R-XTR-429594 SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-444433 https://reactome.org/PathwayBrowser/#/R-XTR-444433 Cho transports from the extracellular space to the cytosol IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-444433 https://reactome.org/PathwayBrowser/#/R-XTR-444433 Cho transports from the extracellular space to the cytosol IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-549129 https://reactome.org/PathwayBrowser/#/R-XTR-549129 OCT1 transports organic cations into hepatic cells IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-549279 https://reactome.org/PathwayBrowser/#/R-XTR-549279 OCT2 mediates tubular uptake of organic cations in the kidney IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-549322 https://reactome.org/PathwayBrowser/#/R-XTR-549322 OCT1 transports organic cations out of hepatic cells IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 15354 R-ALL-264638 Cho [extracellular region] R-XTR-561054 https://reactome.org/PathwayBrowser/#/R-XTR-561054 OCT2 mediates tubular secretion of organic cations in the kidney IEA Xenopus tropicalis 15354 R-ALL-264618 Cho [cytosol] R-XTR-6797956 https://reactome.org/PathwayBrowser/#/R-XTR-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Xenopus tropicalis 15354 R-ALL-6798162 Cho [mitochondrial matrix] R-XTR-6797956 https://reactome.org/PathwayBrowser/#/R-XTR-6797956 SLC44A1 transports Cho from cytosol to mitochondrial matrix IEA Xenopus tropicalis 15355 R-ALL-264643 AcCho [cytosol] R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15355 R-ALL-264643 AcCho [cytosol] R-BTA-264622 https://reactome.org/PathwayBrowser/#/R-BTA-264622 Cho is acetylated to AcCho by CHAT IEA Bos taurus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-BTA-372505 https://reactome.org/PathwayBrowser/#/R-BTA-372505 Acetylcholine synaptic vesicle docking and priming IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-372529 https://reactome.org/PathwayBrowser/#/R-BTA-372529 Release of acetylcholine at the synapse IEA Bos taurus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-BTA-372529 https://reactome.org/PathwayBrowser/#/R-BTA-372529 Release of acetylcholine at the synapse IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-380073 https://reactome.org/PathwayBrowser/#/R-BTA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-383313 https://reactome.org/PathwayBrowser/#/R-BTA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-390649 https://reactome.org/PathwayBrowser/#/R-BTA-390649 CHRM1,3,5 bind acetylcholine IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-390673 https://reactome.org/PathwayBrowser/#/R-BTA-390673 CHRM2,4 bind acetylcholine IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-622325 https://reactome.org/PathwayBrowser/#/R-BTA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-622326 https://reactome.org/PathwayBrowser/#/R-BTA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-629588 https://reactome.org/PathwayBrowser/#/R-BTA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Bos taurus 15355 R-ALL-399976 AcCho [plasma membrane] R-BTA-629595 https://reactome.org/PathwayBrowser/#/R-BTA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-629596 https://reactome.org/PathwayBrowser/#/R-BTA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-ALL-399976 AcCho [plasma membrane] R-BTA-629596 https://reactome.org/PathwayBrowser/#/R-BTA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-629599 https://reactome.org/PathwayBrowser/#/R-BTA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-749454 https://reactome.org/PathwayBrowser/#/R-BTA-749454 The Ligand:GPCR:Gi complex dissociates IEA Bos taurus 15355 R-ALL-372533 AcCho [extracellular region] R-BTA-749456 https://reactome.org/PathwayBrowser/#/R-BTA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Bos taurus 15355 R-ALL-264643 AcCho [cytosol] R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15355 R-ALL-264643 AcCho [cytosol] R-CEL-264622 https://reactome.org/PathwayBrowser/#/R-CEL-264622 Cho is acetylated to AcCho by CHAT IEA Caenorhabditis elegans 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CEL-372505 https://reactome.org/PathwayBrowser/#/R-CEL-372505 Acetylcholine synaptic vesicle docking and priming IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-372529 https://reactome.org/PathwayBrowser/#/R-CEL-372529 Release of acetylcholine at the synapse IEA Caenorhabditis elegans 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CEL-372529 https://reactome.org/PathwayBrowser/#/R-CEL-372529 Release of acetylcholine at the synapse IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-380073 https://reactome.org/PathwayBrowser/#/R-CEL-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-390649 https://reactome.org/PathwayBrowser/#/R-CEL-390649 CHRM1,3,5 bind acetylcholine IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-390673 https://reactome.org/PathwayBrowser/#/R-CEL-390673 CHRM2,4 bind acetylcholine IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-622325 https://reactome.org/PathwayBrowser/#/R-CEL-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-622326 https://reactome.org/PathwayBrowser/#/R-CEL-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-629588 https://reactome.org/PathwayBrowser/#/R-CEL-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-399976 AcCho [plasma membrane] R-CEL-629595 https://reactome.org/PathwayBrowser/#/R-CEL-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-629596 https://reactome.org/PathwayBrowser/#/R-CEL-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-399976 AcCho [plasma membrane] R-CEL-629596 https://reactome.org/PathwayBrowser/#/R-CEL-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-629599 https://reactome.org/PathwayBrowser/#/R-CEL-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-749454 https://reactome.org/PathwayBrowser/#/R-CEL-749454 The Ligand:GPCR:Gi complex dissociates IEA Caenorhabditis elegans 15355 R-ALL-372533 AcCho [extracellular region] R-CEL-749456 https://reactome.org/PathwayBrowser/#/R-CEL-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Caenorhabditis elegans 15355 R-ALL-264643 AcCho [cytosol] R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15355 R-ALL-264643 AcCho [cytosol] R-CFA-264622 https://reactome.org/PathwayBrowser/#/R-CFA-264622 Cho is acetylated to AcCho by CHAT IEA Canis familiaris 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CFA-372505 https://reactome.org/PathwayBrowser/#/R-CFA-372505 Acetylcholine synaptic vesicle docking and priming IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-372529 https://reactome.org/PathwayBrowser/#/R-CFA-372529 Release of acetylcholine at the synapse IEA Canis familiaris 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-CFA-372529 https://reactome.org/PathwayBrowser/#/R-CFA-372529 Release of acetylcholine at the synapse IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-380073 https://reactome.org/PathwayBrowser/#/R-CFA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-383313 https://reactome.org/PathwayBrowser/#/R-CFA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-390649 https://reactome.org/PathwayBrowser/#/R-CFA-390649 CHRM1,3,5 bind acetylcholine IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-390673 https://reactome.org/PathwayBrowser/#/R-CFA-390673 CHRM2,4 bind acetylcholine IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-622325 https://reactome.org/PathwayBrowser/#/R-CFA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-622326 https://reactome.org/PathwayBrowser/#/R-CFA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-629588 https://reactome.org/PathwayBrowser/#/R-CFA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-399976 AcCho [plasma membrane] R-CFA-629595 https://reactome.org/PathwayBrowser/#/R-CFA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-629596 https://reactome.org/PathwayBrowser/#/R-CFA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-399976 AcCho [plasma membrane] R-CFA-629596 https://reactome.org/PathwayBrowser/#/R-CFA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-629599 https://reactome.org/PathwayBrowser/#/R-CFA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-749454 https://reactome.org/PathwayBrowser/#/R-CFA-749454 The Ligand:GPCR:Gi complex dissociates IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-CFA-749456 https://reactome.org/PathwayBrowser/#/R-CFA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Canis familiaris 15355 R-ALL-372533 AcCho [extracellular region] R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15355 R-ALL-264643 AcCho [cytosol] R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15355 R-ALL-264643 AcCho [cytosol] R-DME-264622 https://reactome.org/PathwayBrowser/#/R-DME-264622 Cho is acetylated to AcCho by CHAT IEA Drosophila melanogaster 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-DME-372505 https://reactome.org/PathwayBrowser/#/R-DME-372505 Acetylcholine synaptic vesicle docking and priming IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-DME-372529 https://reactome.org/PathwayBrowser/#/R-DME-372529 Release of acetylcholine at the synapse IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-379048 https://reactome.org/PathwayBrowser/#/R-DME-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-380073 https://reactome.org/PathwayBrowser/#/R-DME-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-390649 https://reactome.org/PathwayBrowser/#/R-DME-390649 CHRM1,3,5 bind acetylcholine IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-390673 https://reactome.org/PathwayBrowser/#/R-DME-390673 CHRM2,4 bind acetylcholine IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-622325 https://reactome.org/PathwayBrowser/#/R-DME-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-622326 https://reactome.org/PathwayBrowser/#/R-DME-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-629588 https://reactome.org/PathwayBrowser/#/R-DME-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-399976 AcCho [plasma membrane] R-DME-629595 https://reactome.org/PathwayBrowser/#/R-DME-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-629596 https://reactome.org/PathwayBrowser/#/R-DME-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-399976 AcCho [plasma membrane] R-DME-629596 https://reactome.org/PathwayBrowser/#/R-DME-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-629599 https://reactome.org/PathwayBrowser/#/R-DME-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-749448 https://reactome.org/PathwayBrowser/#/R-DME-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-749454 https://reactome.org/PathwayBrowser/#/R-DME-749454 The Ligand:GPCR:Gi complex dissociates IEA Drosophila melanogaster 15355 R-ALL-372533 AcCho [extracellular region] R-DME-749456 https://reactome.org/PathwayBrowser/#/R-DME-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Drosophila melanogaster 15355 R-ALL-264643 AcCho [cytosol] R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15355 R-ALL-264643 AcCho [cytosol] R-DRE-264622 https://reactome.org/PathwayBrowser/#/R-DRE-264622 Cho is acetylated to AcCho by CHAT IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-380073 https://reactome.org/PathwayBrowser/#/R-DRE-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-390649 https://reactome.org/PathwayBrowser/#/R-DRE-390649 CHRM1,3,5 bind acetylcholine IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-390673 https://reactome.org/PathwayBrowser/#/R-DRE-390673 CHRM2,4 bind acetylcholine IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-622326 https://reactome.org/PathwayBrowser/#/R-DRE-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Danio rerio 15355 R-ALL-399976 AcCho [plasma membrane] R-DRE-629595 https://reactome.org/PathwayBrowser/#/R-DRE-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-629596 https://reactome.org/PathwayBrowser/#/R-DRE-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 15355 R-ALL-399976 AcCho [plasma membrane] R-DRE-629596 https://reactome.org/PathwayBrowser/#/R-DRE-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Danio rerio 15355 R-ALL-372533 AcCho [extracellular region] R-DRE-629599 https://reactome.org/PathwayBrowser/#/R-DRE-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Danio rerio 15355 R-ALL-264643 AcCho [cytosol] R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15355 R-ALL-264643 AcCho [cytosol] R-GGA-264622 https://reactome.org/PathwayBrowser/#/R-GGA-264622 Cho is acetylated to AcCho by CHAT IEA Gallus gallus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-GGA-372505 https://reactome.org/PathwayBrowser/#/R-GGA-372505 Acetylcholine synaptic vesicle docking and priming IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-380073 https://reactome.org/PathwayBrowser/#/R-GGA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-383313 https://reactome.org/PathwayBrowser/#/R-GGA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-390649 https://reactome.org/PathwayBrowser/#/R-GGA-390649 CHRM1,3,5 bind acetylcholine IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-390673 https://reactome.org/PathwayBrowser/#/R-GGA-390673 CHRM2,4 bind acetylcholine IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-622325 https://reactome.org/PathwayBrowser/#/R-GGA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-622326 https://reactome.org/PathwayBrowser/#/R-GGA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-629588 https://reactome.org/PathwayBrowser/#/R-GGA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-399976 AcCho [plasma membrane] R-GGA-629595 https://reactome.org/PathwayBrowser/#/R-GGA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-629596 https://reactome.org/PathwayBrowser/#/R-GGA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-399976 AcCho [plasma membrane] R-GGA-629596 https://reactome.org/PathwayBrowser/#/R-GGA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-629599 https://reactome.org/PathwayBrowser/#/R-GGA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-749454 https://reactome.org/PathwayBrowser/#/R-GGA-749454 The Ligand:GPCR:Gi complex dissociates IEA Gallus gallus 15355 R-ALL-372533 AcCho [extracellular region] R-GGA-749456 https://reactome.org/PathwayBrowser/#/R-GGA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Gallus gallus 15355 R-ALL-264643 AcCho [cytosol] R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15355 R-ALL-264643 AcCho [cytosol] R-HSA-264622 https://reactome.org/PathwayBrowser/#/R-HSA-264622 Cho is acetylated to AcCho by CHAT TAS Homo sapiens 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-HSA-372505 https://reactome.org/PathwayBrowser/#/R-HSA-372505 Acetylcholine synaptic vesicle docking and priming TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-372529 https://reactome.org/PathwayBrowser/#/R-HSA-372529 Release of acetylcholine at the synapse TAS Homo sapiens 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-HSA-372529 https://reactome.org/PathwayBrowser/#/R-HSA-372529 Release of acetylcholine at the synapse TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-380073 https://reactome.org/PathwayBrowser/#/R-HSA-380073 Liganded Gi-activating GPCR acts as a GEF for Gi TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-383313 https://reactome.org/PathwayBrowser/#/R-HSA-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-390649 https://reactome.org/PathwayBrowser/#/R-HSA-390649 CHRM1,3,5 bind acetylcholine TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-390673 https://reactome.org/PathwayBrowser/#/R-HSA-390673 CHRM2,4 bind acetylcholine TAS Homo sapiens 15355 R-ALL-399976 AcCho [plasma membrane] R-HSA-399995 https://reactome.org/PathwayBrowser/#/R-HSA-399995 Muscarinic Acetylcholine Receptor M3 activates Gq IEA Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-400012 https://reactome.org/PathwayBrowser/#/R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 IEA Homo sapiens 15355 R-ALL-399976 AcCho [plasma membrane] R-HSA-400012 https://reactome.org/PathwayBrowser/#/R-HSA-400012 Acetylcholine binds Muscarinic Acetylcholine Receptor M3 IEA Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-622325 https://reactome.org/PathwayBrowser/#/R-HSA-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-622326 https://reactome.org/PathwayBrowser/#/R-HSA-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-629588 https://reactome.org/PathwayBrowser/#/R-HSA-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-399976 AcCho [plasma membrane] R-HSA-629595 https://reactome.org/PathwayBrowser/#/R-HSA-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-629596 https://reactome.org/PathwayBrowser/#/R-HSA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-399976 AcCho [plasma membrane] R-HSA-629596 https://reactome.org/PathwayBrowser/#/R-HSA-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-629599 https://reactome.org/PathwayBrowser/#/R-HSA-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-749454 https://reactome.org/PathwayBrowser/#/R-HSA-749454 The Ligand:GPCR:Gi complex dissociates TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-749456 https://reactome.org/PathwayBrowser/#/R-HSA-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi TAS Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-9663736 https://reactome.org/PathwayBrowser/#/R-HSA-9663736 CHRNA9:CHRNA10 binds acetylcholine IEA Homo sapiens 15355 R-ALL-372533 AcCho [extracellular region] R-HSA-9663785 https://reactome.org/PathwayBrowser/#/R-HSA-9663785 CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol IEA Homo sapiens 15355 R-ALL-264643 AcCho [cytosol] R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15355 R-ALL-264643 AcCho [cytosol] R-MMU-264622 https://reactome.org/PathwayBrowser/#/R-MMU-264622 Cho is acetylated to AcCho by CHAT IEA Mus musculus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-MMU-372505 https://reactome.org/PathwayBrowser/#/R-MMU-372505 Acetylcholine synaptic vesicle docking and priming IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-372529 https://reactome.org/PathwayBrowser/#/R-MMU-372529 Release of acetylcholine at the synapse IEA Mus musculus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-MMU-372529 https://reactome.org/PathwayBrowser/#/R-MMU-372529 Release of acetylcholine at the synapse IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-380073 https://reactome.org/PathwayBrowser/#/R-MMU-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-383313 https://reactome.org/PathwayBrowser/#/R-MMU-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-390649 https://reactome.org/PathwayBrowser/#/R-MMU-390649 CHRM1,3,5 bind acetylcholine IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-390673 https://reactome.org/PathwayBrowser/#/R-MMU-390673 CHRM2,4 bind acetylcholine IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-426547 https://reactome.org/PathwayBrowser/#/R-MMU-426547 Activation of Gq by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-426560 https://reactome.org/PathwayBrowser/#/R-MMU-426560 Binding of Acetylcholine by Muscarinic Acetylcholine Receptor M3 TAS Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-622325 https://reactome.org/PathwayBrowser/#/R-MMU-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-622326 https://reactome.org/PathwayBrowser/#/R-MMU-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-629588 https://reactome.org/PathwayBrowser/#/R-MMU-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Mus musculus 15355 R-ALL-399976 AcCho [plasma membrane] R-MMU-629595 https://reactome.org/PathwayBrowser/#/R-MMU-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-629596 https://reactome.org/PathwayBrowser/#/R-MMU-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-ALL-399976 AcCho [plasma membrane] R-MMU-629596 https://reactome.org/PathwayBrowser/#/R-MMU-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-629599 https://reactome.org/PathwayBrowser/#/R-MMU-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-749454 https://reactome.org/PathwayBrowser/#/R-MMU-749454 The Ligand:GPCR:Gi complex dissociates IEA Mus musculus 15355 R-ALL-372533 AcCho [extracellular region] R-MMU-749456 https://reactome.org/PathwayBrowser/#/R-MMU-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Mus musculus 15355 R-ALL-264643 AcCho [cytosol] R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15355 R-ALL-264643 AcCho [cytosol] R-RNO-264622 https://reactome.org/PathwayBrowser/#/R-RNO-264622 Cho is acetylated to AcCho by CHAT IEA Rattus norvegicus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-RNO-372505 https://reactome.org/PathwayBrowser/#/R-RNO-372505 Acetylcholine synaptic vesicle docking and priming IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-372529 https://reactome.org/PathwayBrowser/#/R-RNO-372529 Release of acetylcholine at the synapse IEA Rattus norvegicus 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-RNO-372529 https://reactome.org/PathwayBrowser/#/R-RNO-372529 Release of acetylcholine at the synapse IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-380073 https://reactome.org/PathwayBrowser/#/R-RNO-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-383313 https://reactome.org/PathwayBrowser/#/R-RNO-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-390649 https://reactome.org/PathwayBrowser/#/R-RNO-390649 CHRM1,3,5 bind acetylcholine IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-390673 https://reactome.org/PathwayBrowser/#/R-RNO-390673 CHRM2,4 bind acetylcholine IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-622325 https://reactome.org/PathwayBrowser/#/R-RNO-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-622326 https://reactome.org/PathwayBrowser/#/R-RNO-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-629588 https://reactome.org/PathwayBrowser/#/R-RNO-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-399976 AcCho [plasma membrane] R-RNO-629595 https://reactome.org/PathwayBrowser/#/R-RNO-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-629596 https://reactome.org/PathwayBrowser/#/R-RNO-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-399976 AcCho [plasma membrane] R-RNO-629596 https://reactome.org/PathwayBrowser/#/R-RNO-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-629599 https://reactome.org/PathwayBrowser/#/R-RNO-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-9667850 https://reactome.org/PathwayBrowser/#/R-RNO-9667850 Chrna9:Chrna10:AcCho transports calcium ions from the extracellular region to the cytosol TAS Rattus norvegicus 15355 R-ALL-372533 AcCho [extracellular region] R-RNO-9667857 https://reactome.org/PathwayBrowser/#/R-RNO-9667857 Chrna9:Chrna10 binds acetylcholine (AcCho) TAS Rattus norvegicus 15355 R-ALL-264643 AcCho [cytosol] R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15355 R-ALL-264643 AcCho [cytosol] R-SSC-264622 https://reactome.org/PathwayBrowser/#/R-SSC-264622 Cho is acetylated to AcCho by CHAT IEA Sus scrofa 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-SSC-372505 https://reactome.org/PathwayBrowser/#/R-SSC-372505 Acetylcholine synaptic vesicle docking and priming IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-SSC-372529 https://reactome.org/PathwayBrowser/#/R-SSC-372529 Release of acetylcholine at the synapse IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-380073 https://reactome.org/PathwayBrowser/#/R-SSC-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-383313 https://reactome.org/PathwayBrowser/#/R-SSC-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-390649 https://reactome.org/PathwayBrowser/#/R-SSC-390649 CHRM1,3,5 bind acetylcholine IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-390673 https://reactome.org/PathwayBrowser/#/R-SSC-390673 CHRM2,4 bind acetylcholine IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-622326 https://reactome.org/PathwayBrowser/#/R-SSC-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-ALL-399976 AcCho [plasma membrane] R-SSC-629595 https://reactome.org/PathwayBrowser/#/R-SSC-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-ALL-399976 AcCho [plasma membrane] R-SSC-629596 https://reactome.org/PathwayBrowser/#/R-SSC-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-629599 https://reactome.org/PathwayBrowser/#/R-SSC-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-749454 https://reactome.org/PathwayBrowser/#/R-SSC-749454 The Ligand:GPCR:Gi complex dissociates IEA Sus scrofa 15355 R-ALL-372533 AcCho [extracellular region] R-SSC-749456 https://reactome.org/PathwayBrowser/#/R-SSC-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Sus scrofa 15355 R-ALL-264643 AcCho [cytosol] R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15355 R-ALL-264788 O-acetylcholine [clathrin-sculpted acetylcholine transport vesicle lumen] R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-380073 https://reactome.org/PathwayBrowser/#/R-XTR-380073 Liganded Gi-activating GPCR acts as a GEF for Gi IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-383313 https://reactome.org/PathwayBrowser/#/R-XTR-383313 Glucagon-like Peptide 1 is secreted from intestinal L cells IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-390649 https://reactome.org/PathwayBrowser/#/R-XTR-390649 CHRM1,3,5 bind acetylcholine IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-390673 https://reactome.org/PathwayBrowser/#/R-XTR-390673 CHRM2,4 bind acetylcholine IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-622325 https://reactome.org/PathwayBrowser/#/R-XTR-622325 Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-622326 https://reactome.org/PathwayBrowser/#/R-XTR-622326 Activation of highly calcium permeable nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-629588 https://reactome.org/PathwayBrowser/#/R-XTR-629588 Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-399976 AcCho [plasma membrane] R-XTR-629595 https://reactome.org/PathwayBrowser/#/R-XTR-629595 Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-629596 https://reactome.org/PathwayBrowser/#/R-XTR-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-399976 AcCho [plasma membrane] R-XTR-629596 https://reactome.org/PathwayBrowser/#/R-XTR-629596 Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-629599 https://reactome.org/PathwayBrowser/#/R-XTR-629599 Binding of acetylcholine to highly calcium permeable acetylcholine receptors IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-749454 https://reactome.org/PathwayBrowser/#/R-XTR-749454 The Ligand:GPCR:Gi complex dissociates IEA Xenopus tropicalis 15355 R-ALL-372533 AcCho [extracellular region] R-XTR-749456 https://reactome.org/PathwayBrowser/#/R-XTR-749456 Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to pyruvate and H2S IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 15361 R-ALL-389680 PYR [peroxisomal matrix] R-BTA-389684 https://reactome.org/PathwayBrowser/#/R-BTA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-4085217 https://reactome.org/PathwayBrowser/#/R-BTA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-429750 PYR [extracellular region] R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-429750 PYR [extracellular region] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-507749 https://reactome.org/PathwayBrowser/#/R-BTA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-507775 https://reactome.org/PathwayBrowser/#/R-BTA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-6784423 https://reactome.org/PathwayBrowser/#/R-BTA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-70523 https://reactome.org/PathwayBrowser/#/R-BTA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-70524 https://reactome.org/PathwayBrowser/#/R-BTA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-429750 PYR [extracellular region] R-BTA-8876312 https://reactome.org/PathwayBrowser/#/R-BTA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-893593 https://reactome.org/PathwayBrowser/#/R-BTA-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-893616 https://reactome.org/PathwayBrowser/#/R-BTA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9012268 https://reactome.org/PathwayBrowser/#/R-BTA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9012349 https://reactome.org/PathwayBrowser/#/R-BTA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9012374 https://reactome.org/PathwayBrowser/#/R-BTA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Bos taurus 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-BTA-9012374 https://reactome.org/PathwayBrowser/#/R-BTA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9012721 https://reactome.org/PathwayBrowser/#/R-BTA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9013471 https://reactome.org/PathwayBrowser/#/R-BTA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9013533 https://reactome.org/PathwayBrowser/#/R-BTA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9014741 https://reactome.org/PathwayBrowser/#/R-BTA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9034539 https://reactome.org/PathwayBrowser/#/R-BTA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9034756 https://reactome.org/PathwayBrowser/#/R-BTA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-904864 https://reactome.org/PathwayBrowser/#/R-BTA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-429750 PYR [extracellular region] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-BTA-9929460 https://reactome.org/PathwayBrowser/#/R-BTA-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Bos taurus 15361 R-ALL-29398 PYR [cytosol] R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to pyruvate and H2S IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 15361 R-ALL-389680 PYR [peroxisomal matrix] R-CEL-389684 https://reactome.org/PathwayBrowser/#/R-CEL-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-429750 PYR [extracellular region] R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-429750 PYR [extracellular region] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-507749 https://reactome.org/PathwayBrowser/#/R-CEL-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-507775 https://reactome.org/PathwayBrowser/#/R-CEL-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-70523 https://reactome.org/PathwayBrowser/#/R-CEL-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-70524 https://reactome.org/PathwayBrowser/#/R-CEL-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-429750 PYR [extracellular region] R-CEL-8876312 https://reactome.org/PathwayBrowser/#/R-CEL-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-893593 https://reactome.org/PathwayBrowser/#/R-CEL-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-893616 https://reactome.org/PathwayBrowser/#/R-CEL-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9012268 https://reactome.org/PathwayBrowser/#/R-CEL-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9012349 https://reactome.org/PathwayBrowser/#/R-CEL-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9012374 https://reactome.org/PathwayBrowser/#/R-CEL-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Caenorhabditis elegans 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-CEL-9012374 https://reactome.org/PathwayBrowser/#/R-CEL-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9012721 https://reactome.org/PathwayBrowser/#/R-CEL-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9013471 https://reactome.org/PathwayBrowser/#/R-CEL-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9013533 https://reactome.org/PathwayBrowser/#/R-CEL-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9014741 https://reactome.org/PathwayBrowser/#/R-CEL-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9034539 https://reactome.org/PathwayBrowser/#/R-CEL-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9034756 https://reactome.org/PathwayBrowser/#/R-CEL-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-904864 https://reactome.org/PathwayBrowser/#/R-CEL-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-429750 PYR [extracellular region] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 15361 R-ALL-29398 PYR [cytosol] R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to pyruvate and H2S IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 15361 R-ALL-389680 PYR [peroxisomal matrix] R-CFA-389684 https://reactome.org/PathwayBrowser/#/R-CFA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-4085217 https://reactome.org/PathwayBrowser/#/R-CFA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-429750 PYR [extracellular region] R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-429750 PYR [extracellular region] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-507749 https://reactome.org/PathwayBrowser/#/R-CFA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-507775 https://reactome.org/PathwayBrowser/#/R-CFA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-6784423 https://reactome.org/PathwayBrowser/#/R-CFA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-70523 https://reactome.org/PathwayBrowser/#/R-CFA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-70524 https://reactome.org/PathwayBrowser/#/R-CFA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-429750 PYR [extracellular region] R-CFA-8876312 https://reactome.org/PathwayBrowser/#/R-CFA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-893593 https://reactome.org/PathwayBrowser/#/R-CFA-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-893616 https://reactome.org/PathwayBrowser/#/R-CFA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9012268 https://reactome.org/PathwayBrowser/#/R-CFA-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9012349 https://reactome.org/PathwayBrowser/#/R-CFA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9012374 https://reactome.org/PathwayBrowser/#/R-CFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Canis familiaris 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-CFA-9012374 https://reactome.org/PathwayBrowser/#/R-CFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9012721 https://reactome.org/PathwayBrowser/#/R-CFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9013471 https://reactome.org/PathwayBrowser/#/R-CFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9013533 https://reactome.org/PathwayBrowser/#/R-CFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9014741 https://reactome.org/PathwayBrowser/#/R-CFA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9034539 https://reactome.org/PathwayBrowser/#/R-CFA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9034756 https://reactome.org/PathwayBrowser/#/R-CFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-904864 https://reactome.org/PathwayBrowser/#/R-CFA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-429750 PYR [extracellular region] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 15361 R-ALL-113557 PYR [mitochondrial matrix] R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-CFA-9929460 https://reactome.org/PathwayBrowser/#/R-CFA-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Canis familiaris 15361 R-ALL-29398 PYR [cytosol] R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to pyruvate and H2S IEA Dictyostelium discoideum 15361 R-ALL-389680 PYR [peroxisomal matrix] R-DDI-389684 https://reactome.org/PathwayBrowser/#/R-DDI-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-507749 https://reactome.org/PathwayBrowser/#/R-DDI-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-507775 https://reactome.org/PathwayBrowser/#/R-DDI-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-70523 https://reactome.org/PathwayBrowser/#/R-DDI-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-70524 https://reactome.org/PathwayBrowser/#/R-DDI-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-893593 https://reactome.org/PathwayBrowser/#/R-DDI-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-893616 https://reactome.org/PathwayBrowser/#/R-DDI-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-9012374 https://reactome.org/PathwayBrowser/#/R-DDI-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Dictyostelium discoideum 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-DDI-9012374 https://reactome.org/PathwayBrowser/#/R-DDI-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9012721 https://reactome.org/PathwayBrowser/#/R-DDI-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9013471 https://reactome.org/PathwayBrowser/#/R-DDI-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9013533 https://reactome.org/PathwayBrowser/#/R-DDI-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-9014741 https://reactome.org/PathwayBrowser/#/R-DDI-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-9034539 https://reactome.org/PathwayBrowser/#/R-DDI-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9034756 https://reactome.org/PathwayBrowser/#/R-DDI-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Dictyostelium discoideum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DDI-9929460 https://reactome.org/PathwayBrowser/#/R-DDI-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Dictyostelium discoideum 15361 R-ALL-29398 PYR [cytosol] R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to pyruvate and H2S IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 15361 R-ALL-389680 PYR [peroxisomal matrix] R-DME-389684 https://reactome.org/PathwayBrowser/#/R-DME-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-429750 PYR [extracellular region] R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-429750 PYR [extracellular region] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-507749 https://reactome.org/PathwayBrowser/#/R-DME-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-507775 https://reactome.org/PathwayBrowser/#/R-DME-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-70523 https://reactome.org/PathwayBrowser/#/R-DME-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-70524 https://reactome.org/PathwayBrowser/#/R-DME-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-429750 PYR [extracellular region] R-DME-8876312 https://reactome.org/PathwayBrowser/#/R-DME-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-893593 https://reactome.org/PathwayBrowser/#/R-DME-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-893616 https://reactome.org/PathwayBrowser/#/R-DME-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-9012268 https://reactome.org/PathwayBrowser/#/R-DME-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-9012349 https://reactome.org/PathwayBrowser/#/R-DME-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-9012374 https://reactome.org/PathwayBrowser/#/R-DME-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Drosophila melanogaster 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-DME-9012374 https://reactome.org/PathwayBrowser/#/R-DME-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-904864 https://reactome.org/PathwayBrowser/#/R-DME-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-429750 PYR [extracellular region] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 15361 R-ALL-29398 PYR [cytosol] R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to pyruvate and H2S IEA Danio rerio 15361 R-ALL-389680 PYR [peroxisomal matrix] R-DRE-389684 https://reactome.org/PathwayBrowser/#/R-DRE-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-4085217 https://reactome.org/PathwayBrowser/#/R-DRE-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-429750 PYR [extracellular region] R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-429750 PYR [extracellular region] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-6784423 https://reactome.org/PathwayBrowser/#/R-DRE-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-70523 https://reactome.org/PathwayBrowser/#/R-DRE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-70524 https://reactome.org/PathwayBrowser/#/R-DRE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-429750 PYR [extracellular region] R-DRE-8876312 https://reactome.org/PathwayBrowser/#/R-DRE-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-893593 https://reactome.org/PathwayBrowser/#/R-DRE-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-893616 https://reactome.org/PathwayBrowser/#/R-DRE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9012268 https://reactome.org/PathwayBrowser/#/R-DRE-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9012349 https://reactome.org/PathwayBrowser/#/R-DRE-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-9012374 https://reactome.org/PathwayBrowser/#/R-DRE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Danio rerio 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-DRE-9012374 https://reactome.org/PathwayBrowser/#/R-DRE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9012721 https://reactome.org/PathwayBrowser/#/R-DRE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9013471 https://reactome.org/PathwayBrowser/#/R-DRE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9013533 https://reactome.org/PathwayBrowser/#/R-DRE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-9034756 https://reactome.org/PathwayBrowser/#/R-DRE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Danio rerio 15361 R-ALL-113557 PYR [mitochondrial matrix] R-DRE-904864 https://reactome.org/PathwayBrowser/#/R-DRE-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 15361 R-ALL-29398 PYR [cytosol] R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to pyruvate and H2S IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-353056 https://reactome.org/PathwayBrowser/#/R-GGA-353056 phosphoenolpyruvate + ADP => pyruvate + ATP TAS Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-353154 https://reactome.org/PathwayBrowser/#/R-GGA-353154 pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate TAS Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 15361 R-ALL-389680 PYR [peroxisomal matrix] R-GGA-389684 https://reactome.org/PathwayBrowser/#/R-GGA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-4085217 https://reactome.org/PathwayBrowser/#/R-GGA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-429750 PYR [extracellular region] R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-429750 PYR [extracellular region] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-507749 https://reactome.org/PathwayBrowser/#/R-GGA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-507775 https://reactome.org/PathwayBrowser/#/R-GGA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-6784423 https://reactome.org/PathwayBrowser/#/R-GGA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-429750 PYR [extracellular region] R-GGA-8876312 https://reactome.org/PathwayBrowser/#/R-GGA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-893593 https://reactome.org/PathwayBrowser/#/R-GGA-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-893616 https://reactome.org/PathwayBrowser/#/R-GGA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9012349 https://reactome.org/PathwayBrowser/#/R-GGA-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-GGA-9012374 https://reactome.org/PathwayBrowser/#/R-GGA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9012721 https://reactome.org/PathwayBrowser/#/R-GGA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9013471 https://reactome.org/PathwayBrowser/#/R-GGA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9013533 https://reactome.org/PathwayBrowser/#/R-GGA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9014741 https://reactome.org/PathwayBrowser/#/R-GGA-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9034539 https://reactome.org/PathwayBrowser/#/R-GGA-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9034756 https://reactome.org/PathwayBrowser/#/R-GGA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-904864 https://reactome.org/PathwayBrowser/#/R-GGA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-429750 PYR [extracellular region] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-GGA-9929460 https://reactome.org/PathwayBrowser/#/R-GGA-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Gallus gallus 15361 R-ALL-29398 PYR [cytosol] R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to pyruvate and H2S TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15361 R-ALL-389680 PYR [peroxisomal matrix] R-HSA-389684 https://reactome.org/PathwayBrowser/#/R-HSA-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-4085217 https://reactome.org/PathwayBrowser/#/R-HSA-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-429750 PYR [extracellular region] R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-429750 PYR [extracellular region] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-507749 https://reactome.org/PathwayBrowser/#/R-HSA-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-507775 https://reactome.org/PathwayBrowser/#/R-HSA-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR TAS Homo sapiens 15361 R-ALL-429750 PYR [extracellular region] R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-1130930 PYR [cytoplasm] R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-6784423 https://reactome.org/PathwayBrowser/#/R-HSA-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-70523 https://reactome.org/PathwayBrowser/#/R-HSA-70523 PXLP-K314-GPT transaminates L-Ala to form PYR TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-70524 https://reactome.org/PathwayBrowser/#/R-HSA-70524 PXLP-K314-GPT transaminates PYR to form L-Ala TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-429750 PYR [extracellular region] R-HSA-8876312 https://reactome.org/PathwayBrowser/#/R-HSA-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-893593 https://reactome.org/PathwayBrowser/#/R-HSA-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-893616 https://reactome.org/PathwayBrowser/#/R-HSA-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9012268 https://reactome.org/PathwayBrowser/#/R-HSA-9012268 ME2 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9012349 https://reactome.org/PathwayBrowser/#/R-HSA-9012349 ME3 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9012374 https://reactome.org/PathwayBrowser/#/R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space TAS Homo sapiens 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-HSA-9012374 https://reactome.org/PathwayBrowser/#/R-HSA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9012721 https://reactome.org/PathwayBrowser/#/R-HSA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9013471 https://reactome.org/PathwayBrowser/#/R-HSA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9013533 https://reactome.org/PathwayBrowser/#/R-HSA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9014741 https://reactome.org/PathwayBrowser/#/R-HSA-9014741 PXLP-K56-SRR dimer deaminates D-Ser TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9034539 https://reactome.org/PathwayBrowser/#/R-HSA-9034539 PXLP-K56-SRR dimer deaminates L-Ser TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9034756 https://reactome.org/PathwayBrowser/#/R-HSA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-904864 https://reactome.org/PathwayBrowser/#/R-HSA-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-909776 https://reactome.org/PathwayBrowser/#/R-HSA-909776 beta-alanine + pyruvate => 3-oxopropanoate + alanine IEA Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-909780 https://reactome.org/PathwayBrowser/#/R-HSA-909780 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine IEA Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-429750 PYR [extracellular region] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 15361 R-ALL-113557 PYR [mitochondrial matrix] R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-HSA-9929460 https://reactome.org/PathwayBrowser/#/R-HSA-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ TAS Homo sapiens 15361 R-ALL-29398 PYR [cytosol] R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to pyruvate and H2S IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 15361 R-ALL-389680 PYR [peroxisomal matrix] R-MMU-389684 https://reactome.org/PathwayBrowser/#/R-MMU-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-4085217 https://reactome.org/PathwayBrowser/#/R-MMU-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-429750 PYR [extracellular region] R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-429750 PYR [extracellular region] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-507749 https://reactome.org/PathwayBrowser/#/R-MMU-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-507775 https://reactome.org/PathwayBrowser/#/R-MMU-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-6784423 https://reactome.org/PathwayBrowser/#/R-MMU-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-70523 https://reactome.org/PathwayBrowser/#/R-MMU-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-70524 https://reactome.org/PathwayBrowser/#/R-MMU-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-429750 PYR [extracellular region] R-MMU-8876312 https://reactome.org/PathwayBrowser/#/R-MMU-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-893593 https://reactome.org/PathwayBrowser/#/R-MMU-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-893616 https://reactome.org/PathwayBrowser/#/R-MMU-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9012268 https://reactome.org/PathwayBrowser/#/R-MMU-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9012349 https://reactome.org/PathwayBrowser/#/R-MMU-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9012374 https://reactome.org/PathwayBrowser/#/R-MMU-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Mus musculus 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-MMU-9012374 https://reactome.org/PathwayBrowser/#/R-MMU-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9012721 https://reactome.org/PathwayBrowser/#/R-MMU-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9013471 https://reactome.org/PathwayBrowser/#/R-MMU-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9013533 https://reactome.org/PathwayBrowser/#/R-MMU-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9014741 https://reactome.org/PathwayBrowser/#/R-MMU-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9034539 https://reactome.org/PathwayBrowser/#/R-MMU-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9034756 https://reactome.org/PathwayBrowser/#/R-MMU-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-904864 https://reactome.org/PathwayBrowser/#/R-MMU-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-429750 PYR [extracellular region] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-MMU-9929460 https://reactome.org/PathwayBrowser/#/R-MMU-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Mus musculus 15361 R-ALL-29398 PYR [cytosol] R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 15361 R-ALL-29398 PYR [cytosol] R-PFA-9012374 https://reactome.org/PathwayBrowser/#/R-PFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Plasmodium falciparum 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-PFA-9012374 https://reactome.org/PathwayBrowser/#/R-PFA-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Plasmodium falciparum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-PFA-9012721 https://reactome.org/PathwayBrowser/#/R-PFA-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Plasmodium falciparum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-PFA-9013471 https://reactome.org/PathwayBrowser/#/R-PFA-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Plasmodium falciparum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-PFA-9013533 https://reactome.org/PathwayBrowser/#/R-PFA-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Plasmodium falciparum 15361 R-ALL-113557 PYR [mitochondrial matrix] R-PFA-9034756 https://reactome.org/PathwayBrowser/#/R-PFA-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Plasmodium falciparum 15361 R-ALL-29398 PYR [cytosol] R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to pyruvate and H2S IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15361 R-ALL-389680 PYR [peroxisomal matrix] R-RNO-389684 https://reactome.org/PathwayBrowser/#/R-RNO-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-4085217 https://reactome.org/PathwayBrowser/#/R-RNO-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-429750 PYR [extracellular region] R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-429750 PYR [extracellular region] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-507749 https://reactome.org/PathwayBrowser/#/R-RNO-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-507775 https://reactome.org/PathwayBrowser/#/R-RNO-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-6784423 https://reactome.org/PathwayBrowser/#/R-RNO-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-70523 https://reactome.org/PathwayBrowser/#/R-RNO-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-70524 https://reactome.org/PathwayBrowser/#/R-RNO-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-429750 PYR [extracellular region] R-RNO-8876312 https://reactome.org/PathwayBrowser/#/R-RNO-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-893593 https://reactome.org/PathwayBrowser/#/R-RNO-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-893616 https://reactome.org/PathwayBrowser/#/R-RNO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9012268 https://reactome.org/PathwayBrowser/#/R-RNO-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9012349 https://reactome.org/PathwayBrowser/#/R-RNO-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9012374 https://reactome.org/PathwayBrowser/#/R-RNO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-RNO-9012374 https://reactome.org/PathwayBrowser/#/R-RNO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9012721 https://reactome.org/PathwayBrowser/#/R-RNO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9013471 https://reactome.org/PathwayBrowser/#/R-RNO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9013533 https://reactome.org/PathwayBrowser/#/R-RNO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9014741 https://reactome.org/PathwayBrowser/#/R-RNO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9034539 https://reactome.org/PathwayBrowser/#/R-RNO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9034756 https://reactome.org/PathwayBrowser/#/R-RNO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-904864 https://reactome.org/PathwayBrowser/#/R-RNO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-909762 https://reactome.org/PathwayBrowser/#/R-RNO-909762 beta-alanine + pyruvate => 3-oxopropanoate + alanine TAS Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-909775 https://reactome.org/PathwayBrowser/#/R-RNO-909775 (R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine TAS Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-429750 PYR [extracellular region] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 15361 R-ALL-113557 PYR [mitochondrial matrix] R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-RNO-9929460 https://reactome.org/PathwayBrowser/#/R-RNO-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Rattus norvegicus 15361 R-ALL-29398 PYR [cytosol] R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to pyruvate and H2S IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-507749 https://reactome.org/PathwayBrowser/#/R-SCE-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-507775 https://reactome.org/PathwayBrowser/#/R-SCE-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 15361 R-ALL-1130930 PYR [cytoplasm] R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-70523 https://reactome.org/PathwayBrowser/#/R-SCE-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-70524 https://reactome.org/PathwayBrowser/#/R-SCE-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-893593 https://reactome.org/PathwayBrowser/#/R-SCE-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-893616 https://reactome.org/PathwayBrowser/#/R-SCE-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-9012374 https://reactome.org/PathwayBrowser/#/R-SCE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Saccharomyces cerevisiae 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-SCE-9012374 https://reactome.org/PathwayBrowser/#/R-SCE-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9012721 https://reactome.org/PathwayBrowser/#/R-SCE-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9013471 https://reactome.org/PathwayBrowser/#/R-SCE-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9013533 https://reactome.org/PathwayBrowser/#/R-SCE-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-9014741 https://reactome.org/PathwayBrowser/#/R-SCE-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-9034539 https://reactome.org/PathwayBrowser/#/R-SCE-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9034756 https://reactome.org/PathwayBrowser/#/R-SCE-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Saccharomyces cerevisiae 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SCE-9929460 https://reactome.org/PathwayBrowser/#/R-SCE-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Saccharomyces cerevisiae 15361 R-ALL-29398 PYR [cytosol] R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to pyruvate and H2S IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-893593 https://reactome.org/PathwayBrowser/#/R-SPO-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-893616 https://reactome.org/PathwayBrowser/#/R-SPO-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-9012374 https://reactome.org/PathwayBrowser/#/R-SPO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Schizosaccharomyces pombe 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-SPO-9012374 https://reactome.org/PathwayBrowser/#/R-SPO-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9012721 https://reactome.org/PathwayBrowser/#/R-SPO-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9013471 https://reactome.org/PathwayBrowser/#/R-SPO-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9013533 https://reactome.org/PathwayBrowser/#/R-SPO-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-9014741 https://reactome.org/PathwayBrowser/#/R-SPO-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SPO-9034539 https://reactome.org/PathwayBrowser/#/R-SPO-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9034756 https://reactome.org/PathwayBrowser/#/R-SPO-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-904864 https://reactome.org/PathwayBrowser/#/R-SPO-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Schizosaccharomyces pombe 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 15361 R-ALL-29398 PYR [cytosol] R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to pyruvate and H2S IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 15361 R-ALL-389680 PYR [peroxisomal matrix] R-SSC-389684 https://reactome.org/PathwayBrowser/#/R-SSC-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-4085217 https://reactome.org/PathwayBrowser/#/R-SSC-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-429750 PYR [extracellular region] R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-429750 PYR [extracellular region] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-507749 https://reactome.org/PathwayBrowser/#/R-SSC-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-507775 https://reactome.org/PathwayBrowser/#/R-SSC-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-6784423 https://reactome.org/PathwayBrowser/#/R-SSC-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-70523 https://reactome.org/PathwayBrowser/#/R-SSC-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-70524 https://reactome.org/PathwayBrowser/#/R-SSC-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-429750 PYR [extracellular region] R-SSC-8876312 https://reactome.org/PathwayBrowser/#/R-SSC-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-893593 https://reactome.org/PathwayBrowser/#/R-SSC-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-893616 https://reactome.org/PathwayBrowser/#/R-SSC-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9012268 https://reactome.org/PathwayBrowser/#/R-SSC-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9012349 https://reactome.org/PathwayBrowser/#/R-SSC-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9012374 https://reactome.org/PathwayBrowser/#/R-SSC-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Sus scrofa 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-SSC-9012374 https://reactome.org/PathwayBrowser/#/R-SSC-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9012721 https://reactome.org/PathwayBrowser/#/R-SSC-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9013471 https://reactome.org/PathwayBrowser/#/R-SSC-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9013533 https://reactome.org/PathwayBrowser/#/R-SSC-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9014741 https://reactome.org/PathwayBrowser/#/R-SSC-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9034539 https://reactome.org/PathwayBrowser/#/R-SSC-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9034756 https://reactome.org/PathwayBrowser/#/R-SSC-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-904864 https://reactome.org/PathwayBrowser/#/R-SSC-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-429750 PYR [extracellular region] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 15361 R-ALL-113557 PYR [mitochondrial matrix] R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-SSC-9929460 https://reactome.org/PathwayBrowser/#/R-SSC-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Sus scrofa 15361 R-ALL-29398 PYR [cytosol] R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to pyruvate and H2S IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 15361 R-ALL-389680 PYR [peroxisomal matrix] R-XTR-389684 https://reactome.org/PathwayBrowser/#/R-XTR-389684 glyoxylate + alanine => glycine + pyruvate [peroxisome] IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-4085217 https://reactome.org/PathwayBrowser/#/R-XTR-4085217 NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-429750 PYR [extracellular region] R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-507749 https://reactome.org/PathwayBrowser/#/R-XTR-507749 PXLP-K341-GPT2 transaminates PYR to form L-Ala IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-507775 https://reactome.org/PathwayBrowser/#/R-XTR-507775 PXLP-K341-GPT2 transaminates L-Ala to form PYR IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-6784423 https://reactome.org/PathwayBrowser/#/R-XTR-6784423 HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-70523 https://reactome.org/PathwayBrowser/#/R-XTR-70523 PXLP-K314-GPT transaminates L-Ala to form PYR IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-70524 https://reactome.org/PathwayBrowser/#/R-XTR-70524 PXLP-K314-GPT transaminates PYR to form L-Ala IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-429750 PYR [extracellular region] R-XTR-8876312 https://reactome.org/PathwayBrowser/#/R-XTR-8876312 SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-893593 https://reactome.org/PathwayBrowser/#/R-XTR-893593 phenylalanine + pyruvate => keto-phenylpyruvate + alanine IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-893616 https://reactome.org/PathwayBrowser/#/R-XTR-893616 glutamine + pyruvate => 2-oxoglutaramate + alanine IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9012268 https://reactome.org/PathwayBrowser/#/R-XTR-9012268 ME2 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9012349 https://reactome.org/PathwayBrowser/#/R-XTR-9012349 ME3 tetramer decarboxylates MAL to PYR IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-9012374 https://reactome.org/PathwayBrowser/#/R-XTR-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 15361 R-ALL-9012375 PYR [mitochondrial intermembrane space] R-XTR-9012374 https://reactome.org/PathwayBrowser/#/R-XTR-9012374 VDAC1 transports PYR from cytosol to mitochondrial intermembrane space IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9012721 https://reactome.org/PathwayBrowser/#/R-XTR-9012721 MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9013471 https://reactome.org/PathwayBrowser/#/R-XTR-9013471 MPST transfers sulfur from 3MPYR to HCN to form HSCN IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9013533 https://reactome.org/PathwayBrowser/#/R-XTR-9013533 MPST transfers sulfur from sulfanegen to HCN to form HSCN IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-9014741 https://reactome.org/PathwayBrowser/#/R-XTR-9014741 PXLP-K56-SRR dimer deaminates D-Ser IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-9034539 https://reactome.org/PathwayBrowser/#/R-XTR-9034539 PXLP-K56-SRR dimer deaminates L-Ser IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9034756 https://reactome.org/PathwayBrowser/#/R-XTR-9034756 MPST transfers sulfur atom from 3MPYR to form CysS248-MPST IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-904864 https://reactome.org/PathwayBrowser/#/R-XTR-904864 Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-429750 PYR [extracellular region] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15361 R-ALL-113557 PYR [mitochondrial matrix] R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 15361 R-ALL-29398 PYR [cytosol] R-XTR-9929460 https://reactome.org/PathwayBrowser/#/R-XTR-9929460 SDS dimers:PXLP convert L-Ser to PYR and NH4+ IEA Xenopus tropicalis 15365 R-ALL-2314693 ASA- [cytosol] R-BTA-2314678 https://reactome.org/PathwayBrowser/#/R-BTA-2314678 ASA- acetylates PTGS1 IEA Bos taurus 15365 R-ALL-2314693 ASA- [cytosol] R-BTA-2314686 https://reactome.org/PathwayBrowser/#/R-BTA-2314686 ASA- acetylates PTGS2 IEA Bos taurus 15365 R-ALL-9649959 aspirin [extracellular region] R-BTA-9649963 https://reactome.org/PathwayBrowser/#/R-BTA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Bos taurus 15365 R-ALL-9649959 aspirin [extracellular region] R-CEL-9649963 https://reactome.org/PathwayBrowser/#/R-CEL-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Caenorhabditis elegans 15365 R-ALL-2314693 ASA- [cytosol] R-CFA-2314678 https://reactome.org/PathwayBrowser/#/R-CFA-2314678 ASA- acetylates PTGS1 IEA Canis familiaris 15365 R-ALL-2314693 ASA- [cytosol] R-CFA-2314686 https://reactome.org/PathwayBrowser/#/R-CFA-2314686 ASA- acetylates PTGS2 IEA Canis familiaris 15365 R-ALL-9649959 aspirin [extracellular region] R-CFA-9649963 https://reactome.org/PathwayBrowser/#/R-CFA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Canis familiaris 15365 R-ALL-9649959 aspirin [extracellular region] R-DME-9649963 https://reactome.org/PathwayBrowser/#/R-DME-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Drosophila melanogaster 15365 R-ALL-2314693 ASA- [cytosol] R-DRE-2314678 https://reactome.org/PathwayBrowser/#/R-DRE-2314678 ASA- acetylates PTGS1 IEA Danio rerio 15365 R-ALL-2314693 ASA- [cytosol] R-DRE-2314686 https://reactome.org/PathwayBrowser/#/R-DRE-2314686 ASA- acetylates PTGS2 IEA Danio rerio 15365 R-ALL-9649959 aspirin [extracellular region] R-DRE-9649963 https://reactome.org/PathwayBrowser/#/R-DRE-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Danio rerio 15365 R-ALL-2314693 ASA- [cytosol] R-GGA-2314678 https://reactome.org/PathwayBrowser/#/R-GGA-2314678 ASA- acetylates PTGS1 IEA Gallus gallus 15365 R-ALL-2314693 ASA- [cytosol] R-GGA-2314686 https://reactome.org/PathwayBrowser/#/R-GGA-2314686 ASA- acetylates PTGS2 IEA Gallus gallus 15365 R-ALL-9649959 aspirin [extracellular region] R-GGA-9649963 https://reactome.org/PathwayBrowser/#/R-GGA-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Gallus gallus 15365 R-ALL-2314693 ASA- [cytosol] R-HSA-2314678 https://reactome.org/PathwayBrowser/#/R-HSA-2314678 ASA- acetylates PTGS1 TAS Homo sapiens 15365 R-ALL-2314693 ASA- [cytosol] R-HSA-2314686 https://reactome.org/PathwayBrowser/#/R-HSA-2314686 ASA- acetylates PTGS2 TAS Homo sapiens 15365 R-ALL-9649959 aspirin [extracellular region] R-HSA-9649963 https://reactome.org/PathwayBrowser/#/R-HSA-9649963 ASIC3 channel blockers bind ASIC3 trimer TAS Homo sapiens 15365 R-ALL-9749584 ASA [extracellular region] R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15365 R-ALL-2314693 ASA- [cytosol] R-MMU-2314678 https://reactome.org/PathwayBrowser/#/R-MMU-2314678 ASA- acetylates PTGS1 IEA Mus musculus 15365 R-ALL-2314693 ASA- [cytosol] R-MMU-2314686 https://reactome.org/PathwayBrowser/#/R-MMU-2314686 ASA- acetylates PTGS2 IEA Mus musculus 15365 R-ALL-9649959 aspirin [extracellular region] R-MMU-9649963 https://reactome.org/PathwayBrowser/#/R-MMU-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Mus musculus 15365 R-ALL-2314693 ASA- [cytosol] R-RNO-2314678 https://reactome.org/PathwayBrowser/#/R-RNO-2314678 ASA- acetylates PTGS1 IEA Rattus norvegicus 15365 R-ALL-2314693 ASA- [cytosol] R-RNO-2314686 https://reactome.org/PathwayBrowser/#/R-RNO-2314686 ASA- acetylates PTGS2 IEA Rattus norvegicus 15365 R-ALL-9649959 aspirin [extracellular region] R-RNO-9649963 https://reactome.org/PathwayBrowser/#/R-RNO-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Rattus norvegicus 15365 R-ALL-2314693 ASA- [cytosol] R-SSC-2314678 https://reactome.org/PathwayBrowser/#/R-SSC-2314678 ASA- acetylates PTGS1 IEA Sus scrofa 15365 R-ALL-2314693 ASA- [cytosol] R-SSC-2314686 https://reactome.org/PathwayBrowser/#/R-SSC-2314686 ASA- acetylates PTGS2 IEA Sus scrofa 15365 R-ALL-9649959 aspirin [extracellular region] R-SSC-9649963 https://reactome.org/PathwayBrowser/#/R-SSC-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Sus scrofa 15365 R-ALL-2314693 ASA- [cytosol] R-XTR-2314678 https://reactome.org/PathwayBrowser/#/R-XTR-2314678 ASA- acetylates PTGS1 IEA Xenopus tropicalis 15365 R-ALL-2314693 ASA- [cytosol] R-XTR-2314686 https://reactome.org/PathwayBrowser/#/R-XTR-2314686 ASA- acetylates PTGS2 IEA Xenopus tropicalis 15365 R-ALL-9649959 aspirin [extracellular region] R-XTR-9649963 https://reactome.org/PathwayBrowser/#/R-XTR-9649963 ASIC3 channel blockers bind ASIC3 trimer IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-BTA-2022887 https://reactome.org/PathwayBrowser/#/R-BTA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-429749 https://reactome.org/PathwayBrowser/#/R-BTA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-444047 https://reactome.org/PathwayBrowser/#/R-BTA-444047 Receptor FFAR3 binds carboxylates IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-444171 https://reactome.org/PathwayBrowser/#/R-BTA-444171 Receptor FFAR2 binds carboxylates IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-71735 https://reactome.org/PathwayBrowser/#/R-BTA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-BTA-9701565 https://reactome.org/PathwayBrowser/#/R-BTA-9701565 HDACs deacetylate p-STAT3 dimers IEA Bos taurus 15366 R-ALL-372540 CH3COO- [extracellular region] R-BTA-9712210 https://reactome.org/PathwayBrowser/#/R-BTA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Bos taurus 15366 R-ALL-29416 CH3COO- [cytosol] R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-CEL-2022887 https://reactome.org/PathwayBrowser/#/R-CEL-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Caenorhabditis elegans 15366 R-ALL-29416 CH3COO- [cytosol] R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15366 R-ALL-372540 CH3COO- [extracellular region] R-CEL-429749 https://reactome.org/PathwayBrowser/#/R-CEL-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15366 R-ALL-29416 CH3COO- [cytosol] R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15366 R-ALL-29416 CH3COO- [cytosol] R-CEL-71735 https://reactome.org/PathwayBrowser/#/R-CEL-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Caenorhabditis elegans 15366 R-ALL-372540 CH3COO- [extracellular region] R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15366 R-ALL-29416 CH3COO- [cytosol] R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-CEL-9701565 https://reactome.org/PathwayBrowser/#/R-CEL-9701565 HDACs deacetylate p-STAT3 dimers IEA Caenorhabditis elegans 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-CFA-2022887 https://reactome.org/PathwayBrowser/#/R-CFA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-429749 https://reactome.org/PathwayBrowser/#/R-CFA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-444047 https://reactome.org/PathwayBrowser/#/R-CFA-444047 Receptor FFAR3 binds carboxylates IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-444171 https://reactome.org/PathwayBrowser/#/R-CFA-444171 Receptor FFAR2 binds carboxylates IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-71735 https://reactome.org/PathwayBrowser/#/R-CFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-CFA-9701565 https://reactome.org/PathwayBrowser/#/R-CFA-9701565 HDACs deacetylate p-STAT3 dimers IEA Canis familiaris 15366 R-ALL-372540 CH3COO- [extracellular region] R-CFA-9712210 https://reactome.org/PathwayBrowser/#/R-CFA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Canis familiaris 15366 R-ALL-29416 CH3COO- [cytosol] R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 15366 R-ALL-29416 CH3COO- [cytosol] R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15366 R-ALL-29416 CH3COO- [cytosol] R-DDI-71735 https://reactome.org/PathwayBrowser/#/R-DDI-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Dictyostelium discoideum 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-DDI-9701565 https://reactome.org/PathwayBrowser/#/R-DDI-9701565 HDACs deacetylate p-STAT3 dimers IEA Dictyostelium discoideum 15366 R-ALL-29416 CH3COO- [cytosol] R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-DME-2022887 https://reactome.org/PathwayBrowser/#/R-DME-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Drosophila melanogaster 15366 R-ALL-29416 CH3COO- [cytosol] R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15366 R-ALL-372540 CH3COO- [extracellular region] R-DME-429749 https://reactome.org/PathwayBrowser/#/R-DME-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15366 R-ALL-29416 CH3COO- [cytosol] R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15366 R-ALL-29416 CH3COO- [cytosol] R-DME-71735 https://reactome.org/PathwayBrowser/#/R-DME-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Drosophila melanogaster 15366 R-ALL-372540 CH3COO- [extracellular region] R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-DME-8952069 https://reactome.org/PathwayBrowser/#/R-DME-8952069 HDAC4 deacetylates RUNX3 IEA Drosophila melanogaster 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-DME-9701565 https://reactome.org/PathwayBrowser/#/R-DME-9701565 HDACs deacetylate p-STAT3 dimers IEA Drosophila melanogaster 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-DRE-2022887 https://reactome.org/PathwayBrowser/#/R-DRE-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Danio rerio 15366 R-ALL-372540 CH3COO- [extracellular region] R-DRE-379048 https://reactome.org/PathwayBrowser/#/R-DRE-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Danio rerio 15366 R-ALL-29416 CH3COO- [cytosol] R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 15366 R-ALL-372540 CH3COO- [extracellular region] R-DRE-429749 https://reactome.org/PathwayBrowser/#/R-DRE-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Danio rerio 15366 R-ALL-372540 CH3COO- [extracellular region] R-DRE-444047 https://reactome.org/PathwayBrowser/#/R-DRE-444047 Receptor FFAR3 binds carboxylates IEA Danio rerio 15366 R-ALL-372540 CH3COO- [extracellular region] R-DRE-444171 https://reactome.org/PathwayBrowser/#/R-DRE-444171 Receptor FFAR2 binds carboxylates IEA Danio rerio 15366 R-ALL-29416 CH3COO- [cytosol] R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Danio rerio 15366 R-ALL-372540 CH3COO- [extracellular region] R-DRE-9712210 https://reactome.org/PathwayBrowser/#/R-DRE-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Danio rerio 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-429749 https://reactome.org/PathwayBrowser/#/R-GGA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-444171 https://reactome.org/PathwayBrowser/#/R-GGA-444171 Receptor FFAR2 binds carboxylates IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-71735 https://reactome.org/PathwayBrowser/#/R-GGA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus 15366 R-ALL-372540 CH3COO- [extracellular region] R-GGA-9712210 https://reactome.org/PathwayBrowser/#/R-GGA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Gallus gallus 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-HSA-2022887 https://reactome.org/PathwayBrowser/#/R-HSA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-429749 https://reactome.org/PathwayBrowser/#/R-HSA-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol TAS Homo sapiens 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-HSA-433672 https://reactome.org/PathwayBrowser/#/R-HSA-433672 NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 IEA Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-444047 https://reactome.org/PathwayBrowser/#/R-HSA-444047 Receptor FFAR3 binds carboxylates TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-444171 https://reactome.org/PathwayBrowser/#/R-HSA-444171 Receptor FFAR2 binds carboxylates TAS Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate TAS Homo sapiens 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-HSA-5693092 https://reactome.org/PathwayBrowser/#/R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) TAS Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-71735 https://reactome.org/PathwayBrowser/#/R-HSA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-HSA-8952069 https://reactome.org/PathwayBrowser/#/R-HSA-8952069 HDAC4 deacetylates RUNX3 TAS Homo sapiens 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-HSA-9701565 https://reactome.org/PathwayBrowser/#/R-HSA-9701565 HDACs deacetylate p-STAT3 dimers TAS Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-9712201 https://reactome.org/PathwayBrowser/#/R-HSA-9712201 GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 IEA Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-9712208 https://reactome.org/PathwayBrowser/#/R-HSA-9712208 odorant:Olfactory Receptor:GNAL:GTP:GNB1:GNG13 dissociates yielding GNAL:GTP (G alpha-olf:GTP), odorant:OlfactoryReceptor, and GNB1:GNG13 IEA Homo sapiens 15366 R-ALL-372540 CH3COO- [extracellular region] R-HSA-9712210 https://reactome.org/PathwayBrowser/#/R-HSA-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 TAS Homo sapiens 15366 R-ALL-9737107 CH3COOH [extracellular region] R-HSA-9737111 https://reactome.org/PathwayBrowser/#/R-HSA-9737111 Protonated weak acid translocates across the plasma membrane IEA Homo sapiens 15366 R-ALL-9737119 CH3COOH [cytosol] R-HSA-9737111 https://reactome.org/PathwayBrowser/#/R-HSA-9737111 Protonated weak acid translocates across the plasma membrane IEA Homo sapiens 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-MMU-2022887 https://reactome.org/PathwayBrowser/#/R-MMU-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-429749 https://reactome.org/PathwayBrowser/#/R-MMU-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-444047 https://reactome.org/PathwayBrowser/#/R-MMU-444047 Receptor FFAR3 binds carboxylates IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-444171 https://reactome.org/PathwayBrowser/#/R-MMU-444171 Receptor FFAR2 binds carboxylates IEA Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Mus musculus 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-MMU-573376 https://reactome.org/PathwayBrowser/#/R-MMU-573376 NoRC:intergenic spacer:Hdac:Dnmt complex deacetylates histone H4 and dimethylates lysine-9 of histone H3 in main promoter of the rRNA gene TAS Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-71735 https://reactome.org/PathwayBrowser/#/R-MMU-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-MMU-9701565 https://reactome.org/PathwayBrowser/#/R-MMU-9701565 HDACs deacetylate p-STAT3 dimers IEA Mus musculus 15366 R-ALL-372540 CH3COO- [extracellular region] R-MMU-9712210 https://reactome.org/PathwayBrowser/#/R-MMU-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Mus musculus 15366 R-ALL-9737107 CH3COOH [extracellular region] R-MMU-9750040 https://reactome.org/PathwayBrowser/#/R-MMU-9750040 Protonated weak acid translocates across the plasma membrane TAS Mus musculus 15366 R-ALL-9737119 CH3COOH [cytosol] R-MMU-9750040 https://reactome.org/PathwayBrowser/#/R-MMU-9750040 Protonated weak acid translocates across the plasma membrane TAS Mus musculus 15366 R-ALL-29416 CH3COO- [cytosol] R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 15366 R-ALL-29416 CH3COO- [cytosol] R-MTU-936642 https://reactome.org/PathwayBrowser/#/R-MTU-936642 deacetylation of O-acetylserine and sulfhydrylation using CysK1 TAS Mycobacterium tuberculosis 15366 R-ALL-29416 CH3COO- [cytosol] R-MTU-936745 https://reactome.org/PathwayBrowser/#/R-MTU-936745 deacetylation of O-acetylserine and sulfhydrylation using CysK2 TAS Mycobacterium tuberculosis 15366 R-ALL-29416 CH3COO- [cytosol] R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 15366 R-ALL-29416 CH3COO- [cytosol] R-PFA-71735 https://reactome.org/PathwayBrowser/#/R-PFA-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Plasmodium falciparum 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-RNO-2022887 https://reactome.org/PathwayBrowser/#/R-RNO-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Rattus norvegicus 15366 R-ALL-372540 CH3COO- [extracellular region] R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 15366 R-ALL-372540 CH3COO- [extracellular region] R-RNO-429749 https://reactome.org/PathwayBrowser/#/R-RNO-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Rattus norvegicus 15366 R-ALL-372540 CH3COO- [extracellular region] R-RNO-444047 https://reactome.org/PathwayBrowser/#/R-RNO-444047 Receptor FFAR3 binds carboxylates IEA Rattus norvegicus 15366 R-ALL-372540 CH3COO- [extracellular region] R-RNO-444171 https://reactome.org/PathwayBrowser/#/R-RNO-444171 Receptor FFAR2 binds carboxylates IEA Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-71735 https://reactome.org/PathwayBrowser/#/R-RNO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-RNO-9701565 https://reactome.org/PathwayBrowser/#/R-RNO-9701565 HDACs deacetylate p-STAT3 dimers IEA Rattus norvegicus 15366 R-ALL-9737107 CH3COOH [extracellular region] R-RNO-9749957 https://reactome.org/PathwayBrowser/#/R-RNO-9749957 Protonated weak acid translocates across the plasma membrane TAS Rattus norvegicus 15366 R-ALL-9737119 CH3COOH [cytosol] R-RNO-9749957 https://reactome.org/PathwayBrowser/#/R-RNO-9749957 Protonated weak acid translocates across the plasma membrane TAS Rattus norvegicus 15366 R-ALL-29416 CH3COO- [cytosol] R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 15366 R-ALL-29416 CH3COO- [cytosol] R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15366 R-ALL-29416 CH3COO- [cytosol] R-SCE-71735 https://reactome.org/PathwayBrowser/#/R-SCE-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Saccharomyces cerevisiae 15366 R-ALL-29416 CH3COO- [cytosol] R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 15366 R-ALL-29416 CH3COO- [cytosol] R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15366 R-ALL-29416 CH3COO- [cytosol] R-SPO-71735 https://reactome.org/PathwayBrowser/#/R-SPO-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Schizosaccharomyces pombe 15366 R-ALL-29416 CH3COO- [cytosol] R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-429749 https://reactome.org/PathwayBrowser/#/R-SSC-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-444047 https://reactome.org/PathwayBrowser/#/R-SSC-444047 Receptor FFAR3 binds carboxylates IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-444171 https://reactome.org/PathwayBrowser/#/R-SSC-444171 Receptor FFAR2 binds carboxylates IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-71735 https://reactome.org/PathwayBrowser/#/R-SSC-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-SSC-9701565 https://reactome.org/PathwayBrowser/#/R-SSC-9701565 HDACs deacetylate p-STAT3 dimers IEA Sus scrofa 15366 R-ALL-372540 CH3COO- [extracellular region] R-SSC-9712210 https://reactome.org/PathwayBrowser/#/R-SSC-9712210 odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 IEA Sus scrofa 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 15366 R-ALL-2022890 CH3COO- [Golgi lumen] R-XTR-2022887 https://reactome.org/PathwayBrowser/#/R-XTR-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15366 R-ALL-372540 CH3COO- [extracellular region] R-XTR-429749 https://reactome.org/PathwayBrowser/#/R-XTR-429749 SLC5A8 (SMCT) co-transports monocarboxylates and Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15366 R-ALL-372540 CH3COO- [extracellular region] R-XTR-444171 https://reactome.org/PathwayBrowser/#/R-XTR-444171 Receptor FFAR2 binds carboxylates IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-71735 https://reactome.org/PathwayBrowser/#/R-XTR-71735 acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] IEA Xenopus tropicalis 15366 R-ALL-372540 CH3COO- [extracellular region] R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15366 R-ALL-372540 CH3COO- [extracellular region] R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15366 R-ALL-29416 CH3COO- [cytosol] R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 15366 R-ALL-427486 CH3COO- [nucleoplasm] R-XTR-9701565 https://reactome.org/PathwayBrowser/#/R-XTR-9701565 HDACs deacetylate p-STAT3 dimers IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-200406 https://reactome.org/PathwayBrowser/#/R-BTA-200406 CPT1A transfers PALM to CAR IEA Bos taurus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15367 R-ALL-5246462 atRA [extracellular region] R-BTA-5246478 https://reactome.org/PathwayBrowser/#/R-BTA-5246478 APOM binds retinoids IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5334827 https://reactome.org/PathwayBrowser/#/R-BTA-5334827 SUMO-CRABP2 binds atRA IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5334854 https://reactome.org/PathwayBrowser/#/R-BTA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5422942 https://reactome.org/PathwayBrowser/#/R-BTA-5422942 RXRA:PPARD binds FABP5:atRA IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5622129 https://reactome.org/PathwayBrowser/#/R-BTA-5622129 FABP5 binds atRA IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5622134 https://reactome.org/PathwayBrowser/#/R-BTA-5622134 CRABP1 binds atRA IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5633256 https://reactome.org/PathwayBrowser/#/R-BTA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5633256 https://reactome.org/PathwayBrowser/#/R-BTA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5634100 https://reactome.org/PathwayBrowser/#/R-BTA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5634103 https://reactome.org/PathwayBrowser/#/R-BTA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-5634104 https://reactome.org/PathwayBrowser/#/R-BTA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Bos taurus 15367 R-ALL-5334816 atRA [cytosol] R-BTA-5634104 https://reactome.org/PathwayBrowser/#/R-BTA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-8869568 https://reactome.org/PathwayBrowser/#/R-BTA-8869568 NPM1 binds TFAP2A homodimer IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-BTA-9617067 https://reactome.org/PathwayBrowser/#/R-BTA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Bos taurus 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-200406 https://reactome.org/PathwayBrowser/#/R-CEL-200406 CPT1A transfers PALM to CAR IEA Caenorhabditis elegans 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5334827 https://reactome.org/PathwayBrowser/#/R-CEL-5334827 SUMO-CRABP2 binds atRA IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5334854 https://reactome.org/PathwayBrowser/#/R-CEL-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5422942 https://reactome.org/PathwayBrowser/#/R-CEL-5422942 RXRA:PPARD binds FABP5:atRA IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5622129 https://reactome.org/PathwayBrowser/#/R-CEL-5622129 FABP5 binds atRA IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5622134 https://reactome.org/PathwayBrowser/#/R-CEL-5622134 CRABP1 binds atRA IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5633256 https://reactome.org/PathwayBrowser/#/R-CEL-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5633256 https://reactome.org/PathwayBrowser/#/R-CEL-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5634100 https://reactome.org/PathwayBrowser/#/R-CEL-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5634103 https://reactome.org/PathwayBrowser/#/R-CEL-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-5634104 https://reactome.org/PathwayBrowser/#/R-CEL-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Caenorhabditis elegans 15367 R-ALL-5334816 atRA [cytosol] R-CEL-5634104 https://reactome.org/PathwayBrowser/#/R-CEL-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CEL-9617067 https://reactome.org/PathwayBrowser/#/R-CEL-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Caenorhabditis elegans 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-200406 https://reactome.org/PathwayBrowser/#/R-CFA-200406 CPT1A transfers PALM to CAR IEA Canis familiaris 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15367 R-ALL-5246462 atRA [extracellular region] R-CFA-5246478 https://reactome.org/PathwayBrowser/#/R-CFA-5246478 APOM binds retinoids IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5334827 https://reactome.org/PathwayBrowser/#/R-CFA-5334827 SUMO-CRABP2 binds atRA IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5334854 https://reactome.org/PathwayBrowser/#/R-CFA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5422942 https://reactome.org/PathwayBrowser/#/R-CFA-5422942 RXRA:PPARD binds FABP5:atRA IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5622129 https://reactome.org/PathwayBrowser/#/R-CFA-5622129 FABP5 binds atRA IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5622134 https://reactome.org/PathwayBrowser/#/R-CFA-5622134 CRABP1 binds atRA IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5633256 https://reactome.org/PathwayBrowser/#/R-CFA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5633256 https://reactome.org/PathwayBrowser/#/R-CFA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5634100 https://reactome.org/PathwayBrowser/#/R-CFA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5634103 https://reactome.org/PathwayBrowser/#/R-CFA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-5634104 https://reactome.org/PathwayBrowser/#/R-CFA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Canis familiaris 15367 R-ALL-5334816 atRA [cytosol] R-CFA-5634104 https://reactome.org/PathwayBrowser/#/R-CFA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-8869568 https://reactome.org/PathwayBrowser/#/R-CFA-8869568 NPM1 binds TFAP2A homodimer IEA Canis familiaris 15367 R-ALL-5334804 atRA [nucleoplasm] R-CFA-9617067 https://reactome.org/PathwayBrowser/#/R-CFA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Canis familiaris 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15367 R-ALL-5334816 atRA [cytosol] R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-200406 https://reactome.org/PathwayBrowser/#/R-DME-200406 CPT1A transfers PALM to CAR IEA Drosophila melanogaster 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15367 R-ALL-5334816 atRA [cytosol] R-DME-5334827 https://reactome.org/PathwayBrowser/#/R-DME-5334827 SUMO-CRABP2 binds atRA IEA Drosophila melanogaster 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-5334854 https://reactome.org/PathwayBrowser/#/R-DME-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Drosophila melanogaster 15367 R-ALL-5334816 atRA [cytosol] R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15367 R-ALL-5334816 atRA [cytosol] R-DME-5622134 https://reactome.org/PathwayBrowser/#/R-DME-5622134 CRABP1 binds atRA IEA Drosophila melanogaster 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-5634103 https://reactome.org/PathwayBrowser/#/R-DME-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Drosophila melanogaster 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-5634104 https://reactome.org/PathwayBrowser/#/R-DME-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Drosophila melanogaster 15367 R-ALL-5334816 atRA [cytosol] R-DME-5634104 https://reactome.org/PathwayBrowser/#/R-DME-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Drosophila melanogaster 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-8869568 https://reactome.org/PathwayBrowser/#/R-DME-8869568 NPM1 binds TFAP2A homodimer IEA Drosophila melanogaster 15367 R-ALL-5334804 atRA [nucleoplasm] R-DME-9617067 https://reactome.org/PathwayBrowser/#/R-DME-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Drosophila melanogaster 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15367 R-ALL-5334816 atRA [cytosol] R-DRE-5334827 https://reactome.org/PathwayBrowser/#/R-DRE-5334827 SUMO-CRABP2 binds atRA IEA Danio rerio 15367 R-ALL-5334804 atRA [nucleoplasm] R-DRE-5334854 https://reactome.org/PathwayBrowser/#/R-DRE-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Danio rerio 15367 R-ALL-5334816 atRA [cytosol] R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15367 R-ALL-5334816 atRA [cytosol] R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15367 R-ALL-5334816 atRA [cytosol] R-DRE-5622134 https://reactome.org/PathwayBrowser/#/R-DRE-5622134 CRABP1 binds atRA IEA Danio rerio 15367 R-ALL-5334804 atRA [nucleoplasm] R-DRE-5634103 https://reactome.org/PathwayBrowser/#/R-DRE-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Danio rerio 15367 R-ALL-5334804 atRA [nucleoplasm] R-DRE-5634104 https://reactome.org/PathwayBrowser/#/R-DRE-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Danio rerio 15367 R-ALL-5334816 atRA [cytosol] R-DRE-5634104 https://reactome.org/PathwayBrowser/#/R-DRE-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Danio rerio 15367 R-ALL-5334804 atRA [nucleoplasm] R-DRE-9617067 https://reactome.org/PathwayBrowser/#/R-DRE-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Danio rerio 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-200406 https://reactome.org/PathwayBrowser/#/R-GGA-200406 CPT1A transfers PALM to CAR IEA Gallus gallus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5334827 https://reactome.org/PathwayBrowser/#/R-GGA-5334827 SUMO-CRABP2 binds atRA IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5334854 https://reactome.org/PathwayBrowser/#/R-GGA-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5422942 https://reactome.org/PathwayBrowser/#/R-GGA-5422942 RXRA:PPARD binds FABP5:atRA IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5622129 https://reactome.org/PathwayBrowser/#/R-GGA-5622129 FABP5 binds atRA IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5622134 https://reactome.org/PathwayBrowser/#/R-GGA-5622134 CRABP1 binds atRA IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5633256 https://reactome.org/PathwayBrowser/#/R-GGA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5633256 https://reactome.org/PathwayBrowser/#/R-GGA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5634100 https://reactome.org/PathwayBrowser/#/R-GGA-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5634103 https://reactome.org/PathwayBrowser/#/R-GGA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-5634104 https://reactome.org/PathwayBrowser/#/R-GGA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Gallus gallus 15367 R-ALL-5334816 atRA [cytosol] R-GGA-5634104 https://reactome.org/PathwayBrowser/#/R-GGA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-8869568 https://reactome.org/PathwayBrowser/#/R-GGA-8869568 NPM1 binds TFAP2A homodimer IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-GGA-9617067 https://reactome.org/PathwayBrowser/#/R-GGA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Gallus gallus 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-200406 https://reactome.org/PathwayBrowser/#/R-HSA-200406 CPT1A transfers PALM to CAR TAS Homo sapiens 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-5246478 https://reactome.org/PathwayBrowser/#/R-HSA-5246478 APOM binds retinoids TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5334827 https://reactome.org/PathwayBrowser/#/R-HSA-5334827 SUMO-CRABP2 binds atRA TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5334854 https://reactome.org/PathwayBrowser/#/R-HSA-5334854 RAR:RXR binds SUMO-CRABP2:atRA TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5422942 https://reactome.org/PathwayBrowser/#/R-HSA-5422942 RXRA:PPARD binds FABP5:atRA TAS Homo sapiens 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617431 https://reactome.org/PathwayBrowser/#/R-HSA-5617431 Retinoic acid activates HOXA1 chromatin IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617445 https://reactome.org/PathwayBrowser/#/R-HSA-5617445 HOXD1 chromatin is activated IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617452 https://reactome.org/PathwayBrowser/#/R-HSA-5617452 Retinoic acid activates HOXB1 chromatin IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617454 https://reactome.org/PathwayBrowser/#/R-HSA-5617454 HOXB1 gene is transcribed IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617471 https://reactome.org/PathwayBrowser/#/R-HSA-5617471 HOXA1 gene is transcribed IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617650 https://reactome.org/PathwayBrowser/#/R-HSA-5617650 HOXD3 chromatin is activated IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617859 https://reactome.org/PathwayBrowser/#/R-HSA-5617859 Retinoic acid activates HOXB4 chromatin IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617862 https://reactome.org/PathwayBrowser/#/R-HSA-5617862 Retinoic acid activates HOXA4 chromatin IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617867 https://reactome.org/PathwayBrowser/#/R-HSA-5617867 HOXB4 gene is transcribed IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617874 https://reactome.org/PathwayBrowser/#/R-HSA-5617874 HOXD4 gene is transcribed IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617877 https://reactome.org/PathwayBrowser/#/R-HSA-5617877 HOXA4 gene is transcribed IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5617896 https://reactome.org/PathwayBrowser/#/R-HSA-5617896 Retinoic acid activates HOXD4 chromatin IEA Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5622129 https://reactome.org/PathwayBrowser/#/R-HSA-5622129 FABP5 binds atRA TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5622134 https://reactome.org/PathwayBrowser/#/R-HSA-5622134 CRABP1 binds atRA TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5633256 https://reactome.org/PathwayBrowser/#/R-HSA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5633256 https://reactome.org/PathwayBrowser/#/R-HSA-5633256 FABP5:atRA translocates from cytosol to nucleoplasm TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5634100 https://reactome.org/PathwayBrowser/#/R-HSA-5634100 FABP5 dissociates from RXRA:PPARD:atRA TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5634103 https://reactome.org/PathwayBrowser/#/R-HSA-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5634104 https://reactome.org/PathwayBrowser/#/R-HSA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus TAS Homo sapiens 15367 R-ALL-5334816 atRA [cytosol] R-HSA-5634104 https://reactome.org/PathwayBrowser/#/R-HSA-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-5693644 https://reactome.org/PathwayBrowser/#/R-HSA-5693644 HOXB1 maintains activation of HOXB1 chromatin IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-6810139 https://reactome.org/PathwayBrowser/#/R-HSA-6810139 HOXA2 chromatin is activated IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-6810159 https://reactome.org/PathwayBrowser/#/R-HSA-6810159 HOXB2 chromatin is activated IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-8869568 https://reactome.org/PathwayBrowser/#/R-HSA-8869568 NPM1 binds TFAP2A homodimer TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-9617067 https://reactome.org/PathwayBrowser/#/R-HSA-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-9634433 https://reactome.org/PathwayBrowser/#/R-HSA-9634433 CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid IEA Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9761166 https://reactome.org/PathwayBrowser/#/R-HSA-9761166 Expression of LHX1 in intermediate mesoderm IEA Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9761170 https://reactome.org/PathwayBrowser/#/R-HSA-9761170 Expression of PAX2 in intermediate mesoderm IEA Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9761173 https://reactome.org/PathwayBrowser/#/R-HSA-9761173 Expression of PAX8 in intermediate mesoderm IEA Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9761186 https://reactome.org/PathwayBrowser/#/R-HSA-9761186 Expression of OSR1 in intermediate mesoderm IEA Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9830480 https://reactome.org/PathwayBrowser/#/R-HSA-9830480 Expression of RET in the nephric duct IEA Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-9839371 https://reactome.org/PathwayBrowser/#/R-HSA-9839371 TGFBR3 transcription TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-HSA-9860125 https://reactome.org/PathwayBrowser/#/R-HSA-9860125 Binding of ATRA to TGFBR3 gene promoter TAS Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9909325 https://reactome.org/PathwayBrowser/#/R-HSA-9909325 Dorsal foregut endoderm cell produces duodeno-pancreatic endoderm cell TAS Homo sapiens 15367 R-ALL-5246462 atRA [extracellular region] R-HSA-9911210 https://reactome.org/PathwayBrowser/#/R-HSA-9911210 Definitive endoderm cell produces dorsal foregut endoderm cell TAS Homo sapiens 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-200406 https://reactome.org/PathwayBrowser/#/R-MMU-200406 CPT1A transfers PALM to CAR IEA Mus musculus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15367 R-ALL-5246462 atRA [extracellular region] R-MMU-5246478 https://reactome.org/PathwayBrowser/#/R-MMU-5246478 APOM binds retinoids IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5334827 https://reactome.org/PathwayBrowser/#/R-MMU-5334827 SUMO-CRABP2 binds atRA IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5334854 https://reactome.org/PathwayBrowser/#/R-MMU-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5422942 https://reactome.org/PathwayBrowser/#/R-MMU-5422942 RXRA:PPARD binds FABP5:atRA IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5617960 https://reactome.org/PathwayBrowser/#/R-MMU-5617960 Retinoic acid activates Hoxb1 chromatin TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5617972 https://reactome.org/PathwayBrowser/#/R-MMU-5617972 Hoxb1 gene is transcribed TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5617990 https://reactome.org/PathwayBrowser/#/R-MMU-5617990 Retinoic acid activates Hoxa1 chromatin TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5617999 https://reactome.org/PathwayBrowser/#/R-MMU-5617999 Hoxa1 gene is transcribed TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619411 https://reactome.org/PathwayBrowser/#/R-MMU-5619411 Retinoic acid activates Hoxb4 chromatin TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619414 https://reactome.org/PathwayBrowser/#/R-MMU-5619414 Hoxa4 gene is transcribed TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619417 https://reactome.org/PathwayBrowser/#/R-MMU-5619417 Hoxb4 gene is transcribed TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619421 https://reactome.org/PathwayBrowser/#/R-MMU-5619421 Hoxd4 gene is transcribed TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619434 https://reactome.org/PathwayBrowser/#/R-MMU-5619434 Retinoic acid activates Hoxa4 chromatin TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5619441 https://reactome.org/PathwayBrowser/#/R-MMU-5619441 Retinoic acid activates Hoxd4 chromatin TAS Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5622129 https://reactome.org/PathwayBrowser/#/R-MMU-5622129 FABP5 binds atRA IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5622134 https://reactome.org/PathwayBrowser/#/R-MMU-5622134 CRABP1 binds atRA IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5633256 https://reactome.org/PathwayBrowser/#/R-MMU-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5633256 https://reactome.org/PathwayBrowser/#/R-MMU-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5634100 https://reactome.org/PathwayBrowser/#/R-MMU-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5634103 https://reactome.org/PathwayBrowser/#/R-MMU-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5634104 https://reactome.org/PathwayBrowser/#/R-MMU-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Mus musculus 15367 R-ALL-5334816 atRA [cytosol] R-MMU-5634104 https://reactome.org/PathwayBrowser/#/R-MMU-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-5693628 https://reactome.org/PathwayBrowser/#/R-MMU-5693628 Hoxb1 maintains activation of Hoxb1 chromatin TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-8869568 https://reactome.org/PathwayBrowser/#/R-MMU-8869568 NPM1 binds TFAP2A homodimer IEA Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-MMU-9617067 https://reactome.org/PathwayBrowser/#/R-MMU-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Mus musculus 15367 R-ALL-5246462 atRA [extracellular region] R-MMU-9761177 https://reactome.org/PathwayBrowser/#/R-MMU-9761177 Expression of Pax2 in intermediate mesoderm TAS Mus musculus 15367 R-ALL-5246462 atRA [extracellular region] R-MMU-9761192 https://reactome.org/PathwayBrowser/#/R-MMU-9761192 Expression of Pax8 in intermediate mesoderm TAS Mus musculus 15367 R-ALL-5246462 atRA [extracellular region] R-MMU-9766551 https://reactome.org/PathwayBrowser/#/R-MMU-9766551 Expression of Osr1 in intermediate mesoderm TAS Mus musculus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-200406 https://reactome.org/PathwayBrowser/#/R-RNO-200406 CPT1A transfers PALM to CAR IEA Rattus norvegicus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15367 R-ALL-5246462 atRA [extracellular region] R-RNO-5246478 https://reactome.org/PathwayBrowser/#/R-RNO-5246478 APOM binds retinoids IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5334827 https://reactome.org/PathwayBrowser/#/R-RNO-5334827 SUMO-CRABP2 binds atRA IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5334854 https://reactome.org/PathwayBrowser/#/R-RNO-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5422942 https://reactome.org/PathwayBrowser/#/R-RNO-5422942 RXRA:PPARD binds FABP5:atRA IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5622129 https://reactome.org/PathwayBrowser/#/R-RNO-5622129 FABP5 binds atRA IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5622134 https://reactome.org/PathwayBrowser/#/R-RNO-5622134 CRABP1 binds atRA IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5633256 https://reactome.org/PathwayBrowser/#/R-RNO-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5633256 https://reactome.org/PathwayBrowser/#/R-RNO-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5634100 https://reactome.org/PathwayBrowser/#/R-RNO-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5634103 https://reactome.org/PathwayBrowser/#/R-RNO-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-5634104 https://reactome.org/PathwayBrowser/#/R-RNO-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-RNO-5634104 https://reactome.org/PathwayBrowser/#/R-RNO-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-8869568 https://reactome.org/PathwayBrowser/#/R-RNO-8869568 NPM1 binds TFAP2A homodimer IEA Rattus norvegicus 15367 R-ALL-5334804 atRA [nucleoplasm] R-RNO-9617067 https://reactome.org/PathwayBrowser/#/R-RNO-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Rattus norvegicus 15367 R-ALL-5334816 atRA [cytosol] R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15367 R-ALL-5334816 atRA [cytosol] R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-200406 https://reactome.org/PathwayBrowser/#/R-SSC-200406 CPT1A transfers PALM to CAR IEA Sus scrofa 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15367 R-ALL-5246462 atRA [extracellular region] R-SSC-5246478 https://reactome.org/PathwayBrowser/#/R-SSC-5246478 APOM binds retinoids IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5334827 https://reactome.org/PathwayBrowser/#/R-SSC-5334827 SUMO-CRABP2 binds atRA IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5334854 https://reactome.org/PathwayBrowser/#/R-SSC-5334854 RAR:RXR binds SUMO-CRABP2:atRA IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5422942 https://reactome.org/PathwayBrowser/#/R-SSC-5422942 RXRA:PPARD binds FABP5:atRA IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5622129 https://reactome.org/PathwayBrowser/#/R-SSC-5622129 FABP5 binds atRA IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5622134 https://reactome.org/PathwayBrowser/#/R-SSC-5622134 CRABP1 binds atRA IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5633256 https://reactome.org/PathwayBrowser/#/R-SSC-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5633256 https://reactome.org/PathwayBrowser/#/R-SSC-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5634100 https://reactome.org/PathwayBrowser/#/R-SSC-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5634103 https://reactome.org/PathwayBrowser/#/R-SSC-5634103 SUMO-CRABP2 dissociates from atRA:RAR:RXR IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-5634104 https://reactome.org/PathwayBrowser/#/R-SSC-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Sus scrofa 15367 R-ALL-5334816 atRA [cytosol] R-SSC-5634104 https://reactome.org/PathwayBrowser/#/R-SSC-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-8869568 https://reactome.org/PathwayBrowser/#/R-SSC-8869568 NPM1 binds TFAP2A homodimer IEA Sus scrofa 15367 R-ALL-5334804 atRA [nucleoplasm] R-SSC-9617067 https://reactome.org/PathwayBrowser/#/R-SSC-9617067 All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene IEA Sus scrofa 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15367 R-ALL-215573 atRA [endoplasmic reticulum lumen] R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15367 R-ALL-5246462 atRA [extracellular region] R-XTR-5246478 https://reactome.org/PathwayBrowser/#/R-XTR-5246478 APOM binds retinoids IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5334827 https://reactome.org/PathwayBrowser/#/R-XTR-5334827 SUMO-CRABP2 binds atRA IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-XTR-5422942 https://reactome.org/PathwayBrowser/#/R-XTR-5422942 RXRA:PPARD binds FABP5:atRA IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5622129 https://reactome.org/PathwayBrowser/#/R-XTR-5622129 FABP5 binds atRA IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5622134 https://reactome.org/PathwayBrowser/#/R-XTR-5622134 CRABP1 binds atRA IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-XTR-5633256 https://reactome.org/PathwayBrowser/#/R-XTR-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5633256 https://reactome.org/PathwayBrowser/#/R-XTR-5633256 FABP5:atRA translocates from cytosol to nucleoplasm IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-XTR-5634100 https://reactome.org/PathwayBrowser/#/R-XTR-5634100 FABP5 dissociates from RXRA:PPARD:atRA IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-XTR-5634104 https://reactome.org/PathwayBrowser/#/R-XTR-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Xenopus tropicalis 15367 R-ALL-5334816 atRA [cytosol] R-XTR-5634104 https://reactome.org/PathwayBrowser/#/R-XTR-5634104 SUMO-CRABP2:atRA translocates from cytosol to nucleus IEA Xenopus tropicalis 15367 R-ALL-5334804 atRA [nucleoplasm] R-XTR-8869568 https://reactome.org/PathwayBrowser/#/R-XTR-8869568 NPM1 binds TFAP2A homodimer IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-BTA-109278 https://reactome.org/PathwayBrowser/#/R-BTA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-109291 https://reactome.org/PathwayBrowser/#/R-BTA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109380 https://reactome.org/PathwayBrowser/#/R-BTA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109387 https://reactome.org/PathwayBrowser/#/R-BTA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109415 https://reactome.org/PathwayBrowser/#/R-BTA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109449 https://reactome.org/PathwayBrowser/#/R-BTA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109470 https://reactome.org/PathwayBrowser/#/R-BTA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-109480 https://reactome.org/PathwayBrowser/#/R-BTA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-109514 https://reactome.org/PathwayBrowser/#/R-BTA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111742 https://reactome.org/PathwayBrowser/#/R-BTA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111751 https://reactome.org/PathwayBrowser/#/R-BTA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111804 https://reactome.org/PathwayBrowser/#/R-BTA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111879 https://reactome.org/PathwayBrowser/#/R-BTA-111879 PIP2 hydrolysis IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111955 https://reactome.org/PathwayBrowser/#/R-BTA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-111962 https://reactome.org/PathwayBrowser/#/R-BTA-111962 PDE4A,C,D hydrolyse cAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-112037 https://reactome.org/PathwayBrowser/#/R-BTA-112037 Inactivation of PLC beta IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-113503 https://reactome.org/PathwayBrowser/#/R-BTA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1169192 https://reactome.org/PathwayBrowser/#/R-BTA-1169192 PTP1B dephosphorylates GHR IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1183128 https://reactome.org/PathwayBrowser/#/R-BTA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1237129 https://reactome.org/PathwayBrowser/#/R-BTA-1237129 Acireductone is created IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1247910 https://reactome.org/PathwayBrowser/#/R-BTA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1247935 https://reactome.org/PathwayBrowser/#/R-BTA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-1363274 https://reactome.org/PathwayBrowser/#/R-BTA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-1363276 https://reactome.org/PathwayBrowser/#/R-BTA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1369065 https://reactome.org/PathwayBrowser/#/R-BTA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-139906 https://reactome.org/PathwayBrowser/#/R-BTA-139906 Activation of BAD by calcineurin IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-140359 https://reactome.org/PathwayBrowser/#/R-BTA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1454916 https://reactome.org/PathwayBrowser/#/R-BTA-1454916 The ABCC family mediates organic anion transport IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1454928 https://reactome.org/PathwayBrowser/#/R-BTA-1454928 ABCG4 may mediate cholesterol efflux IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1467457 https://reactome.org/PathwayBrowser/#/R-BTA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1467466 https://reactome.org/PathwayBrowser/#/R-BTA-1467466 ABCA4 mediates atRAL transport IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1474146 https://reactome.org/PathwayBrowser/#/R-BTA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482543 https://reactome.org/PathwayBrowser/#/R-BTA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482604 https://reactome.org/PathwayBrowser/#/R-BTA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482612 https://reactome.org/PathwayBrowser/#/R-BTA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482656 https://reactome.org/PathwayBrowser/#/R-BTA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482679 https://reactome.org/PathwayBrowser/#/R-BTA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482685 https://reactome.org/PathwayBrowser/#/R-BTA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1482745 https://reactome.org/PathwayBrowser/#/R-BTA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1482759 https://reactome.org/PathwayBrowser/#/R-BTA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482771 https://reactome.org/PathwayBrowser/#/R-BTA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482776 https://reactome.org/PathwayBrowser/#/R-BTA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482777 https://reactome.org/PathwayBrowser/#/R-BTA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482811 https://reactome.org/PathwayBrowser/#/R-BTA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482816 https://reactome.org/PathwayBrowser/#/R-BTA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482825 https://reactome.org/PathwayBrowser/#/R-BTA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482828 https://reactome.org/PathwayBrowser/#/R-BTA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1482847 https://reactome.org/PathwayBrowser/#/R-BTA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482856 https://reactome.org/PathwayBrowser/#/R-BTA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482862 https://reactome.org/PathwayBrowser/#/R-BTA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482868 https://reactome.org/PathwayBrowser/#/R-BTA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482884 https://reactome.org/PathwayBrowser/#/R-BTA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482887 https://reactome.org/PathwayBrowser/#/R-BTA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482897 https://reactome.org/PathwayBrowser/#/R-BTA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482900 https://reactome.org/PathwayBrowser/#/R-BTA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482907 https://reactome.org/PathwayBrowser/#/R-BTA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482920 https://reactome.org/PathwayBrowser/#/R-BTA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1482932 https://reactome.org/PathwayBrowser/#/R-BTA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1483096 https://reactome.org/PathwayBrowser/#/R-BTA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1483159 https://reactome.org/PathwayBrowser/#/R-BTA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1483182 https://reactome.org/PathwayBrowser/#/R-BTA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1483203 https://reactome.org/PathwayBrowser/#/R-BTA-1483203 PA is dephosphorylated to DAG by LPIN IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-159425 https://reactome.org/PathwayBrowser/#/R-BTA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602368 https://reactome.org/PathwayBrowser/#/R-BTA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602374 https://reactome.org/PathwayBrowser/#/R-BTA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602377 https://reactome.org/PathwayBrowser/#/R-BTA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602398 https://reactome.org/PathwayBrowser/#/R-BTA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602399 https://reactome.org/PathwayBrowser/#/R-BTA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602417 https://reactome.org/PathwayBrowser/#/R-BTA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-1602446 https://reactome.org/PathwayBrowser/#/R-BTA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605591 https://reactome.org/PathwayBrowser/#/R-BTA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605595 https://reactome.org/PathwayBrowser/#/R-BTA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605624 https://reactome.org/PathwayBrowser/#/R-BTA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605632 https://reactome.org/PathwayBrowser/#/R-BTA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1605723 https://reactome.org/PathwayBrowser/#/R-BTA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605724 https://reactome.org/PathwayBrowser/#/R-BTA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605736 https://reactome.org/PathwayBrowser/#/R-BTA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1605768 https://reactome.org/PathwayBrowser/#/R-BTA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1606312 https://reactome.org/PathwayBrowser/#/R-BTA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1606564 https://reactome.org/PathwayBrowser/#/R-BTA-1606564 GALC hydrolyzes GalCer IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1606583 https://reactome.org/PathwayBrowser/#/R-BTA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1606602 https://reactome.org/PathwayBrowser/#/R-BTA-1606602 ASAH1 hydrolyzes ceramide IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1606789 https://reactome.org/PathwayBrowser/#/R-BTA-1606789 ARSB hydrolyses DS IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-1606839 https://reactome.org/PathwayBrowser/#/R-BTA-1606839 ARSC hydrolyzes steroid sulfates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1614524 https://reactome.org/PathwayBrowser/#/R-BTA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1614583 https://reactome.org/PathwayBrowser/#/R-BTA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to pyruvate and H2S IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-162425 https://reactome.org/PathwayBrowser/#/R-BTA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-162729 https://reactome.org/PathwayBrowser/#/R-BTA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-162857 https://reactome.org/PathwayBrowser/#/R-BTA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1630304 https://reactome.org/PathwayBrowser/#/R-BTA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1630306 https://reactome.org/PathwayBrowser/#/R-BTA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1638032 https://reactome.org/PathwayBrowser/#/R-BTA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1638053 https://reactome.org/PathwayBrowser/#/R-BTA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1638821 https://reactome.org/PathwayBrowser/#/R-BTA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-164832 https://reactome.org/PathwayBrowser/#/R-BTA-164832 ATPase synthesizes ATP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1667005 https://reactome.org/PathwayBrowser/#/R-BTA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675795 https://reactome.org/PathwayBrowser/#/R-BTA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675824 https://reactome.org/PathwayBrowser/#/R-BTA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675836 https://reactome.org/PathwayBrowser/#/R-BTA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675949 https://reactome.org/PathwayBrowser/#/R-BTA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675988 https://reactome.org/PathwayBrowser/#/R-BTA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1675994 https://reactome.org/PathwayBrowser/#/R-BTA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676005 https://reactome.org/PathwayBrowser/#/R-BTA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676020 https://reactome.org/PathwayBrowser/#/R-BTA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676065 https://reactome.org/PathwayBrowser/#/R-BTA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676105 https://reactome.org/PathwayBrowser/#/R-BTA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676114 https://reactome.org/PathwayBrowser/#/R-BTA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676124 https://reactome.org/PathwayBrowser/#/R-BTA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676141 https://reactome.org/PathwayBrowser/#/R-BTA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676149 https://reactome.org/PathwayBrowser/#/R-BTA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676162 https://reactome.org/PathwayBrowser/#/R-BTA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676164 https://reactome.org/PathwayBrowser/#/R-BTA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676174 https://reactome.org/PathwayBrowser/#/R-BTA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676177 https://reactome.org/PathwayBrowser/#/R-BTA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676203 https://reactome.org/PathwayBrowser/#/R-BTA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1676204 https://reactome.org/PathwayBrowser/#/R-BTA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1678650 https://reactome.org/PathwayBrowser/#/R-BTA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1678708 https://reactome.org/PathwayBrowser/#/R-BTA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1678716 https://reactome.org/PathwayBrowser/#/R-BTA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1678742 https://reactome.org/PathwayBrowser/#/R-BTA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1678854 https://reactome.org/PathwayBrowser/#/R-BTA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-170153 https://reactome.org/PathwayBrowser/#/R-BTA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-170158 https://reactome.org/PathwayBrowser/#/R-BTA-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-170161 https://reactome.org/PathwayBrowser/#/R-BTA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-173739 https://reactome.org/PathwayBrowser/#/R-BTA-173739 Spontaneous hydrolysis of C3 thioester IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-174110 https://reactome.org/PathwayBrowser/#/R-BTA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-174124 https://reactome.org/PathwayBrowser/#/R-BTA-174124 Dephosphorylation of phospho-Cdh1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-174391 https://reactome.org/PathwayBrowser/#/R-BTA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-174401 https://reactome.org/PathwayBrowser/#/R-BTA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-174439 https://reactome.org/PathwayBrowser/#/R-BTA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-176606 https://reactome.org/PathwayBrowser/#/R-BTA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-177923 https://reactome.org/PathwayBrowser/#/R-BTA-177923 Sustained activation of SRC kinase by SHP2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-177924 https://reactome.org/PathwayBrowser/#/R-BTA-177924 Dephosphorylation of Gab1 by SHP2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-177926 https://reactome.org/PathwayBrowser/#/R-BTA-177926 Dephosphorylation of PAG by SHP2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-177935 https://reactome.org/PathwayBrowser/#/R-BTA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1793182 https://reactome.org/PathwayBrowser/#/R-BTA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1793186 https://reactome.org/PathwayBrowser/#/R-BTA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1793207 https://reactome.org/PathwayBrowser/#/R-BTA-1793207 ARSB hydrolyses C4S/C6S chains IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-1793209 https://reactome.org/PathwayBrowser/#/R-BTA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855154 https://reactome.org/PathwayBrowser/#/R-BTA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855159 https://reactome.org/PathwayBrowser/#/R-BTA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-1855163 https://reactome.org/PathwayBrowser/#/R-BTA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855165 https://reactome.org/PathwayBrowser/#/R-BTA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855166 https://reactome.org/PathwayBrowser/#/R-BTA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855171 https://reactome.org/PathwayBrowser/#/R-BTA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855174 https://reactome.org/PathwayBrowser/#/R-BTA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855177 https://reactome.org/PathwayBrowser/#/R-BTA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855180 https://reactome.org/PathwayBrowser/#/R-BTA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855198 https://reactome.org/PathwayBrowser/#/R-BTA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-1855200 https://reactome.org/PathwayBrowser/#/R-BTA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855202 https://reactome.org/PathwayBrowser/#/R-BTA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855205 https://reactome.org/PathwayBrowser/#/R-BTA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855208 https://reactome.org/PathwayBrowser/#/R-BTA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855210 https://reactome.org/PathwayBrowser/#/R-BTA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855211 https://reactome.org/PathwayBrowser/#/R-BTA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855213 https://reactome.org/PathwayBrowser/#/R-BTA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855214 https://reactome.org/PathwayBrowser/#/R-BTA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855218 https://reactome.org/PathwayBrowser/#/R-BTA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855219 https://reactome.org/PathwayBrowser/#/R-BTA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855221 https://reactome.org/PathwayBrowser/#/R-BTA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855222 https://reactome.org/PathwayBrowser/#/R-BTA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-1855225 https://reactome.org/PathwayBrowser/#/R-BTA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1855232 https://reactome.org/PathwayBrowser/#/R-BTA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1861788 https://reactome.org/PathwayBrowser/#/R-BTA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-1861789 https://reactome.org/PathwayBrowser/#/R-BTA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-188979 https://reactome.org/PathwayBrowser/#/R-BTA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-189053 https://reactome.org/PathwayBrowser/#/R-BTA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-189062 https://reactome.org/PathwayBrowser/#/R-BTA-189062 lactose + H2O => D-glucose + D-galactose IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-189069 https://reactome.org/PathwayBrowser/#/R-BTA-189069 sucrose + H2O => glucose + fructose IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-189102 https://reactome.org/PathwayBrowser/#/R-BTA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-189406 https://reactome.org/PathwayBrowser/#/R-BTA-189406 4 PBGs bind to form HMB IEA Bos taurus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-189488 https://reactome.org/PathwayBrowser/#/R-BTA-189488 UROS transforms HMB to URO3 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-191101 https://reactome.org/PathwayBrowser/#/R-BTA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-191108 https://reactome.org/PathwayBrowser/#/R-BTA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-191114 https://reactome.org/PathwayBrowser/#/R-BTA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-191116 https://reactome.org/PathwayBrowser/#/R-BTA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-192331 https://reactome.org/PathwayBrowser/#/R-BTA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192417 https://reactome.org/PathwayBrowser/#/R-BTA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192422 https://reactome.org/PathwayBrowser/#/R-BTA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192425 https://reactome.org/PathwayBrowser/#/R-BTA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192430 https://reactome.org/PathwayBrowser/#/R-BTA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192434 https://reactome.org/PathwayBrowser/#/R-BTA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-192475 https://reactome.org/PathwayBrowser/#/R-BTA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193362 https://reactome.org/PathwayBrowser/#/R-BTA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-193385 https://reactome.org/PathwayBrowser/#/R-BTA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-193535 https://reactome.org/PathwayBrowser/#/R-BTA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193711 https://reactome.org/PathwayBrowser/#/R-BTA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193727 https://reactome.org/PathwayBrowser/#/R-BTA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193743 https://reactome.org/PathwayBrowser/#/R-BTA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193766 https://reactome.org/PathwayBrowser/#/R-BTA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-196950 https://reactome.org/PathwayBrowser/#/R-BTA-196950 2xTRAP hydrolyzes FMN to RIB IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-197186 https://reactome.org/PathwayBrowser/#/R-BTA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-199456 https://reactome.org/PathwayBrowser/#/R-BTA-199456 PTEN dephosphorylates PIP3 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-199959 https://reactome.org/PathwayBrowser/#/R-BTA-199959 ERKs are inactivated by protein phosphatase 2A IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-200661 https://reactome.org/PathwayBrowser/#/R-BTA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-200740 https://reactome.org/PathwayBrowser/#/R-BTA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-201035 https://reactome.org/PathwayBrowser/#/R-BTA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-201790 https://reactome.org/PathwayBrowser/#/R-BTA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-202214 https://reactome.org/PathwayBrowser/#/R-BTA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022368 https://reactome.org/PathwayBrowser/#/R-BTA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-202237 https://reactome.org/PathwayBrowser/#/R-BTA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022378 https://reactome.org/PathwayBrowser/#/R-BTA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022379 https://reactome.org/PathwayBrowser/#/R-BTA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022381 https://reactome.org/PathwayBrowser/#/R-BTA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022383 https://reactome.org/PathwayBrowser/#/R-BTA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022396 https://reactome.org/PathwayBrowser/#/R-BTA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022398 https://reactome.org/PathwayBrowser/#/R-BTA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022399 https://reactome.org/PathwayBrowser/#/R-BTA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022403 https://reactome.org/PathwayBrowser/#/R-BTA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022405 https://reactome.org/PathwayBrowser/#/R-BTA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022411 https://reactome.org/PathwayBrowser/#/R-BTA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2022412 https://reactome.org/PathwayBrowser/#/R-BTA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-ALL-2022884 H2O [Golgi lumen] R-BTA-2022887 https://reactome.org/PathwayBrowser/#/R-BTA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2023971 https://reactome.org/PathwayBrowser/#/R-BTA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2023973 https://reactome.org/PathwayBrowser/#/R-BTA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-202407 https://reactome.org/PathwayBrowser/#/R-BTA-202407 PLC-gamma1 hydrolyses PIP2 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2028294 https://reactome.org/PathwayBrowser/#/R-BTA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2029468 https://reactome.org/PathwayBrowser/#/R-BTA-2029468 Conversion of PA into DAG by PAP-1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2029471 https://reactome.org/PathwayBrowser/#/R-BTA-2029471 Hydrolysis of PC to PA by PLD IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2029475 https://reactome.org/PathwayBrowser/#/R-BTA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 Depalmitoylation of eNOS IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-203797 https://reactome.org/PathwayBrowser/#/R-BTA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-204169 https://reactome.org/PathwayBrowser/#/R-BTA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046083 https://reactome.org/PathwayBrowser/#/R-BTA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046088 https://reactome.org/PathwayBrowser/#/R-BTA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046090 https://reactome.org/PathwayBrowser/#/R-BTA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046094 https://reactome.org/PathwayBrowser/#/R-BTA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046095 https://reactome.org/PathwayBrowser/#/R-BTA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2046100 https://reactome.org/PathwayBrowser/#/R-BTA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2065355 https://reactome.org/PathwayBrowser/#/R-BTA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2065357 https://reactome.org/PathwayBrowser/#/R-BTA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-2066778 https://reactome.org/PathwayBrowser/#/R-BTA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-2066779 https://reactome.org/PathwayBrowser/#/R-BTA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2090037 https://reactome.org/PathwayBrowser/#/R-BTA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2090038 https://reactome.org/PathwayBrowser/#/R-BTA-2090038 NAGLU hydrolyses heparan chain(2) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2090043 https://reactome.org/PathwayBrowser/#/R-BTA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2090079 https://reactome.org/PathwayBrowser/#/R-BTA-2090079 GLB1 hydrolyses linker chain(2) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-209055 https://reactome.org/PathwayBrowser/#/R-BTA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15377 R-ALL-351603 H2O [secretory granule lumen] R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2105001 https://reactome.org/PathwayBrowser/#/R-BTA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2130725 https://reactome.org/PathwayBrowser/#/R-BTA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2160874 https://reactome.org/PathwayBrowser/#/R-BTA-2160874 HYAL1 hydrolyses (HA)50 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161195 https://reactome.org/PathwayBrowser/#/R-BTA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161959 https://reactome.org/PathwayBrowser/#/R-BTA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161961 https://reactome.org/PathwayBrowser/#/R-BTA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2161999 https://reactome.org/PathwayBrowser/#/R-BTA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-2162187 https://reactome.org/PathwayBrowser/#/R-BTA-2162187 COQ6 hydroxylates DHB IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2162225 https://reactome.org/PathwayBrowser/#/R-BTA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2162226 https://reactome.org/PathwayBrowser/#/R-BTA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-2162227 https://reactome.org/PathwayBrowser/#/R-BTA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-216723 https://reactome.org/PathwayBrowser/#/R-BTA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-216757 https://reactome.org/PathwayBrowser/#/R-BTA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2187401 https://reactome.org/PathwayBrowser/#/R-BTA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-2309773 https://reactome.org/PathwayBrowser/#/R-BTA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2393939 https://reactome.org/PathwayBrowser/#/R-BTA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-2393954 https://reactome.org/PathwayBrowser/#/R-BTA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2408551 https://reactome.org/PathwayBrowser/#/R-BTA-2408551 SeMet is converted to AdoSeMet by MAT IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2454118 https://reactome.org/PathwayBrowser/#/R-BTA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2465924 https://reactome.org/PathwayBrowser/#/R-BTA-2465924 OPN1LW binds 11cRAL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2466085 https://reactome.org/PathwayBrowser/#/R-BTA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2466767 https://reactome.org/PathwayBrowser/#/R-BTA-2466767 NRPE is a substrate for Abca4 TAS Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2529015 https://reactome.org/PathwayBrowser/#/R-BTA-2529015 Dephosphorylation of CK2-modified condensin I IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2584246 https://reactome.org/PathwayBrowser/#/R-BTA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2632521 https://reactome.org/PathwayBrowser/#/R-BTA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-265783 https://reactome.org/PathwayBrowser/#/R-BTA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-266012 https://reactome.org/PathwayBrowser/#/R-BTA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-266046 https://reactome.org/PathwayBrowser/#/R-BTA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-266051 https://reactome.org/PathwayBrowser/#/R-BTA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-266070 https://reactome.org/PathwayBrowser/#/R-BTA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-266072 https://reactome.org/PathwayBrowser/#/R-BTA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-266082 https://reactome.org/PathwayBrowser/#/R-BTA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2730847 https://reactome.org/PathwayBrowser/#/R-BTA-2730847 Hydrolysis of PIP2 by PLCG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2730849 https://reactome.org/PathwayBrowser/#/R-BTA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-2855047 https://reactome.org/PathwayBrowser/#/R-BTA-2855047 Hydrolysis of internal thioester in C4b IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-2995330 https://reactome.org/PathwayBrowser/#/R-BTA-2995330 COX10 transforms heme to heme O IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-2995334 https://reactome.org/PathwayBrowser/#/R-BTA-2995334 COX15 transforms heme O to heme A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-2995388 https://reactome.org/PathwayBrowser/#/R-BTA-2995388 PP2A dephosphorylates BANF1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3002811 https://reactome.org/PathwayBrowser/#/R-BTA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3095901 https://reactome.org/PathwayBrowser/#/R-BTA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3215295 https://reactome.org/PathwayBrowser/#/R-BTA-3215295 USP7 deubiquitinates MDM2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3215310 https://reactome.org/PathwayBrowser/#/R-BTA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3247569 https://reactome.org/PathwayBrowser/#/R-BTA-3247569 PADI4 deiminates Histones IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-3262512 https://reactome.org/PathwayBrowser/#/R-BTA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-3266566 https://reactome.org/PathwayBrowser/#/R-BTA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-3322995 https://reactome.org/PathwayBrowser/#/R-BTA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-3323013 https://reactome.org/PathwayBrowser/#/R-BTA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-3341296 https://reactome.org/PathwayBrowser/#/R-BTA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3341343 https://reactome.org/PathwayBrowser/#/R-BTA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-3341397 https://reactome.org/PathwayBrowser/#/R-BTA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3343700 https://reactome.org/PathwayBrowser/#/R-BTA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3371467 https://reactome.org/PathwayBrowser/#/R-BTA-3371467 SIRT1 deacetylates HSF1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-350604 https://reactome.org/PathwayBrowser/#/R-BTA-350604 Agmatine + H2O <=> putrescine + urea IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3640872 https://reactome.org/PathwayBrowser/#/R-BTA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3697882 https://reactome.org/PathwayBrowser/#/R-BTA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-3697894 https://reactome.org/PathwayBrowser/#/R-BTA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3769447 https://reactome.org/PathwayBrowser/#/R-BTA-3769447 HDAC1:2-containing complex deacetylate histones IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-377643 https://reactome.org/PathwayBrowser/#/R-BTA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3777129 https://reactome.org/PathwayBrowser/#/R-BTA-3777129 HDAC3 containing complexes deacetylate histone IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3781011 https://reactome.org/PathwayBrowser/#/R-BTA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-3781018 https://reactome.org/PathwayBrowser/#/R-BTA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3782637 https://reactome.org/PathwayBrowser/#/R-BTA-3782637 HDAC8 deacetylates histones IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-3782655 https://reactome.org/PathwayBrowser/#/R-BTA-3782655 HDAC10 deacetylates histone IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-380949 https://reactome.org/PathwayBrowser/#/R-BTA-380949 AMPK is dephosphorylated IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-382560 https://reactome.org/PathwayBrowser/#/R-BTA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-382575 https://reactome.org/PathwayBrowser/#/R-BTA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-383190 https://reactome.org/PathwayBrowser/#/R-BTA-383190 HCO3- transport through ion channel IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-389986 https://reactome.org/PathwayBrowser/#/R-BTA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-390252 https://reactome.org/PathwayBrowser/#/R-BTA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-390393 https://reactome.org/PathwayBrowser/#/R-BTA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-399998 https://reactome.org/PathwayBrowser/#/R-BTA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4084976 https://reactome.org/PathwayBrowser/#/R-BTA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4084989 https://reactome.org/PathwayBrowser/#/R-BTA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4084994 https://reactome.org/PathwayBrowser/#/R-BTA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-4084999 https://reactome.org/PathwayBrowser/#/R-BTA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4085021 https://reactome.org/PathwayBrowser/#/R-BTA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4085029 https://reactome.org/PathwayBrowser/#/R-BTA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4086392 https://reactome.org/PathwayBrowser/#/R-BTA-4086392 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-4088141 https://reactome.org/PathwayBrowser/#/R-BTA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4093339 https://reactome.org/PathwayBrowser/#/R-BTA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-416559 https://reactome.org/PathwayBrowser/#/R-BTA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-418553 https://reactome.org/PathwayBrowser/#/R-BTA-418553 cAMP degradation by Phosphodiesterases IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428205 https://reactome.org/PathwayBrowser/#/R-BTA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428231 https://reactome.org/PathwayBrowser/#/R-BTA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428262 https://reactome.org/PathwayBrowser/#/R-BTA-428262 ACER3 hydrolyzes phytoceramide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428664 https://reactome.org/PathwayBrowser/#/R-BTA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-428690 https://reactome.org/PathwayBrowser/#/R-BTA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-428696 https://reactome.org/PathwayBrowser/#/R-BTA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429730 https://reactome.org/PathwayBrowser/#/R-BTA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429860 https://reactome.org/PathwayBrowser/#/R-BTA-429860 DCP1-DCP2 complex decaps mRNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429955 https://reactome.org/PathwayBrowser/#/R-BTA-429955 CCR4-NOT complex deadenylates mRNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429961 https://reactome.org/PathwayBrowser/#/R-BTA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-429992 https://reactome.org/PathwayBrowser/#/R-BTA-429992 PARN deadenylates mRNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-430021 https://reactome.org/PathwayBrowser/#/R-BTA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-430028 https://reactome.org/PathwayBrowser/#/R-BTA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-432010 https://reactome.org/PathwayBrowser/#/R-BTA-432010 Aquaporin-1 passively transports water into cell IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-432010 https://reactome.org/PathwayBrowser/#/R-BTA-432010 Aquaporin-1 passively transports water into cell IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-432054 https://reactome.org/PathwayBrowser/#/R-BTA-432054 Aquaporin-1 passively transports water out of cell IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-432054 https://reactome.org/PathwayBrowser/#/R-BTA-432054 Aquaporin-1 passively transports water out of cell IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-432065 https://reactome.org/PathwayBrowser/#/R-BTA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-432065 https://reactome.org/PathwayBrowser/#/R-BTA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-432067 https://reactome.org/PathwayBrowser/#/R-BTA-432067 Aquaporin-4 passively transports water out of cell IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-432067 https://reactome.org/PathwayBrowser/#/R-BTA-432067 Aquaporin-4 passively transports water out of cell IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-4419948 https://reactome.org/PathwayBrowser/#/R-BTA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-445714 https://reactome.org/PathwayBrowser/#/R-BTA-445714 Aquaporin-3 passively transports water out of cell IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-445714 https://reactome.org/PathwayBrowser/#/R-BTA-445714 Aquaporin-3 passively transports water out of cell IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-449937 https://reactome.org/PathwayBrowser/#/R-BTA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-452036 https://reactome.org/PathwayBrowser/#/R-BTA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4551451 https://reactome.org/PathwayBrowser/#/R-BTA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-4641236 https://reactome.org/PathwayBrowser/#/R-BTA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-507868 https://reactome.org/PathwayBrowser/#/R-BTA-507868 Aquaporins passively transport water into cells IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-507868 https://reactome.org/PathwayBrowser/#/R-BTA-507868 Aquaporins passively transport water into cells IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-507870 https://reactome.org/PathwayBrowser/#/R-BTA-507870 Aquaporins passively transport water out of cells IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-507870 https://reactome.org/PathwayBrowser/#/R-BTA-507870 Aquaporins passively transport water out of cells IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5221130 https://reactome.org/PathwayBrowser/#/R-BTA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5223313 https://reactome.org/PathwayBrowser/#/R-BTA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5223317 https://reactome.org/PathwayBrowser/#/R-BTA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5251955 https://reactome.org/PathwayBrowser/#/R-BTA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5251959 https://reactome.org/PathwayBrowser/#/R-BTA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5251989 https://reactome.org/PathwayBrowser/#/R-BTA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5362459 https://reactome.org/PathwayBrowser/#/R-BTA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5433072 https://reactome.org/PathwayBrowser/#/R-BTA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5433074 https://reactome.org/PathwayBrowser/#/R-BTA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-548843 https://reactome.org/PathwayBrowser/#/R-BTA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5603114 https://reactome.org/PathwayBrowser/#/R-BTA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5607735 https://reactome.org/PathwayBrowser/#/R-BTA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5618093 https://reactome.org/PathwayBrowser/#/R-BTA-5618093 ATP hydrolysis by HSP90 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5623513 https://reactome.org/PathwayBrowser/#/R-BTA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5628905 https://reactome.org/PathwayBrowser/#/R-BTA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5631885 https://reactome.org/PathwayBrowser/#/R-BTA-5631885 PRDX1 overoxidizes IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5649705 https://reactome.org/PathwayBrowser/#/R-BTA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5651828 https://reactome.org/PathwayBrowser/#/R-BTA-5651828 PARG dePARylates PARP1,PARP2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5653786 https://reactome.org/PathwayBrowser/#/R-BTA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5659861 https://reactome.org/PathwayBrowser/#/R-BTA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Bos taurus 15377 R-ALL-5668574 H2O [melanosome lumen] R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5665809 https://reactome.org/PathwayBrowser/#/R-BTA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5672957 https://reactome.org/PathwayBrowser/#/R-BTA-5672957 PP2A dephosphorylates KSR1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5672961 https://reactome.org/PathwayBrowser/#/R-BTA-5672961 PP2A dephosphorylates inactive RAFs IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5675373 https://reactome.org/PathwayBrowser/#/R-BTA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5675376 https://reactome.org/PathwayBrowser/#/R-BTA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5675431 https://reactome.org/PathwayBrowser/#/R-BTA-5675431 PP2A dephosphorylates RAF1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5675433 https://reactome.org/PathwayBrowser/#/R-BTA-5675433 PP5 dephosphorylates RAF1 S338 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5676637 https://reactome.org/PathwayBrowser/#/R-BTA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5678706 https://reactome.org/PathwayBrowser/#/R-BTA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5678863 https://reactome.org/PathwayBrowser/#/R-BTA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5679041 https://reactome.org/PathwayBrowser/#/R-BTA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5682285 https://reactome.org/PathwayBrowser/#/R-BTA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5683405 https://reactome.org/PathwayBrowser/#/R-BTA-5683405 PPP5C dephosphorylates TP53BP1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5683714 https://reactome.org/PathwayBrowser/#/R-BTA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5683967 https://reactome.org/PathwayBrowser/#/R-BTA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Bos taurus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-BTA-5684864 https://reactome.org/PathwayBrowser/#/R-BTA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Bos taurus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-BTA-5685902 https://reactome.org/PathwayBrowser/#/R-BTA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5685994 https://reactome.org/PathwayBrowser/#/R-BTA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5687464 https://reactome.org/PathwayBrowser/#/R-BTA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5687664 https://reactome.org/PathwayBrowser/#/R-BTA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5687758 https://reactome.org/PathwayBrowser/#/R-BTA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5688797 https://reactome.org/PathwayBrowser/#/R-BTA-5688797 ATXN3 family cleave Ub chains IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5688837 https://reactome.org/PathwayBrowser/#/R-BTA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5689000 https://reactome.org/PathwayBrowser/#/R-BTA-5689000 AADAC deacetylates PHEN IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5689950 https://reactome.org/PathwayBrowser/#/R-BTA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5689973 https://reactome.org/PathwayBrowser/#/R-BTA-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690043 https://reactome.org/PathwayBrowser/#/R-BTA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5690066 https://reactome.org/PathwayBrowser/#/R-BTA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5690080 https://reactome.org/PathwayBrowser/#/R-BTA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690152 https://reactome.org/PathwayBrowser/#/R-BTA-5690152 USP5 cleaves polyubiquitin IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5690157 https://reactome.org/PathwayBrowser/#/R-BTA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690159 https://reactome.org/PathwayBrowser/#/R-BTA-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690196 https://reactome.org/PathwayBrowser/#/R-BTA-5690196 USP8 deubiquitinates RNF128 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690319 https://reactome.org/PathwayBrowser/#/R-BTA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-5690517 https://reactome.org/PathwayBrowser/#/R-BTA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5690759 https://reactome.org/PathwayBrowser/#/R-BTA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5690790 https://reactome.org/PathwayBrowser/#/R-BTA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690808 https://reactome.org/PathwayBrowser/#/R-BTA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690856 https://reactome.org/PathwayBrowser/#/R-BTA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5690870 https://reactome.org/PathwayBrowser/#/R-BTA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5691381 https://reactome.org/PathwayBrowser/#/R-BTA-5691381 MYSM1 deubiquitinates Histone H2A IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5691411 https://reactome.org/PathwayBrowser/#/R-BTA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5691439 https://reactome.org/PathwayBrowser/#/R-BTA-5691439 BRISC complex deubiquitinates NLRP3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5691507 https://reactome.org/PathwayBrowser/#/R-BTA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5691512 https://reactome.org/PathwayBrowser/#/R-BTA-5691512 APEH hydrolyses NAc-Ser-protein IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5692462 https://reactome.org/PathwayBrowser/#/R-BTA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5692480 https://reactome.org/PathwayBrowser/#/R-BTA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5692754 https://reactome.org/PathwayBrowser/#/R-BTA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5693153 https://reactome.org/PathwayBrowser/#/R-BTA-5693153 PPM1K dephosphorylates p-BCKDH IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5693346 https://reactome.org/PathwayBrowser/#/R-BTA-5693346 CECRI deaminates Ade-Rib to Ino IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5693373 https://reactome.org/PathwayBrowser/#/R-BTA-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5693608 https://reactome.org/PathwayBrowser/#/R-BTA-5693608 Initial resection of double-strand break ends IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-5693724 https://reactome.org/PathwayBrowser/#/R-BTA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5693742 https://reactome.org/PathwayBrowser/#/R-BTA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5693783 https://reactome.org/PathwayBrowser/#/R-BTA-5693783 NAALADases hydrolyse NAAG IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-5693807 https://reactome.org/PathwayBrowser/#/R-BTA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694077 https://reactome.org/PathwayBrowser/#/R-BTA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5694109 https://reactome.org/PathwayBrowser/#/R-BTA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694126 https://reactome.org/PathwayBrowser/#/R-BTA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5694137 https://reactome.org/PathwayBrowser/#/R-BTA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694421 https://reactome.org/PathwayBrowser/#/R-BTA-5694421 PP6 dephosphorylates SEC24 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694485 https://reactome.org/PathwayBrowser/#/R-BTA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5694563 https://reactome.org/PathwayBrowser/#/R-BTA-5694563 ABHD10 hydrolyses MPAG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5694583 https://reactome.org/PathwayBrowser/#/R-BTA-5694583 ABHD4 hydrolyses NAPE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5695964 https://reactome.org/PathwayBrowser/#/R-BTA-5695964 ABHD14B hydrolyses PNPB IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696049 https://reactome.org/PathwayBrowser/#/R-BTA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5696197 https://reactome.org/PathwayBrowser/#/R-BTA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696230 https://reactome.org/PathwayBrowser/#/R-BTA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696365 https://reactome.org/PathwayBrowser/#/R-BTA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5696408 https://reactome.org/PathwayBrowser/#/R-BTA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-5696415 https://reactome.org/PathwayBrowser/#/R-BTA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696465 https://reactome.org/PathwayBrowser/#/R-BTA-5696465 USP45 deubiquitinates ERCC1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696534 https://reactome.org/PathwayBrowser/#/R-BTA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696564 https://reactome.org/PathwayBrowser/#/R-BTA-5696564 USP25 deubiquitinates DDX58 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696600 https://reactome.org/PathwayBrowser/#/R-BTA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696605 https://reactome.org/PathwayBrowser/#/R-BTA-5696605 USP12, USP26 deubiquitinate AR IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696627 https://reactome.org/PathwayBrowser/#/R-BTA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696872 https://reactome.org/PathwayBrowser/#/R-BTA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696914 https://reactome.org/PathwayBrowser/#/R-BTA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696945 https://reactome.org/PathwayBrowser/#/R-BTA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696947 https://reactome.org/PathwayBrowser/#/R-BTA-5696947 USP47 deubiquitinates POLB IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696958 https://reactome.org/PathwayBrowser/#/R-BTA-5696958 USP44 deubiquitinates CDC20 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696960 https://reactome.org/PathwayBrowser/#/R-BTA-5696960 USP49 deubiquitinates H2B IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-5696968 https://reactome.org/PathwayBrowser/#/R-BTA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5696997 https://reactome.org/PathwayBrowser/#/R-BTA-5696997 USP24 deubiquitinates DDB2 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-5697009 https://reactome.org/PathwayBrowser/#/R-BTA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6781764 https://reactome.org/PathwayBrowser/#/R-BTA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6781779 https://reactome.org/PathwayBrowser/#/R-BTA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6781814 https://reactome.org/PathwayBrowser/#/R-BTA-6781814 USP19 deubiquitinates RNF123 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6781897 https://reactome.org/PathwayBrowser/#/R-BTA-6781897 USP11 deubiquitinates NFKBIA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6782069 https://reactome.org/PathwayBrowser/#/R-BTA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6782628 https://reactome.org/PathwayBrowser/#/R-BTA-6782628 USP8 deubiquitinates STAM2:HGS IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6782820 https://reactome.org/PathwayBrowser/#/R-BTA-6782820 USP17 deubiquitinates SUDS3 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6783177 https://reactome.org/PathwayBrowser/#/R-BTA-6783177 USP21 deubiquitinates GATA3,IL33 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6784402 https://reactome.org/PathwayBrowser/#/R-BTA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6784959 https://reactome.org/PathwayBrowser/#/R-BTA-6784959 BPHL hydrolyses VACV to ACV IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6786190 https://reactome.org/PathwayBrowser/#/R-BTA-6786190 CMBL hydrolyses OM to OLMS IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6786421 https://reactome.org/PathwayBrowser/#/R-BTA-6786421 CHIA hydrolyses chitin IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6786650 https://reactome.org/PathwayBrowser/#/R-BTA-6786650 DDHD1,2 hydrolyse PA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6787632 https://reactome.org/PathwayBrowser/#/R-BTA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6788295 https://reactome.org/PathwayBrowser/#/R-BTA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6788912 https://reactome.org/PathwayBrowser/#/R-BTA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Bos taurus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6789310 https://reactome.org/PathwayBrowser/#/R-BTA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6792445 https://reactome.org/PathwayBrowser/#/R-BTA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6792863 https://reactome.org/PathwayBrowser/#/R-BTA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6797627 https://reactome.org/PathwayBrowser/#/R-BTA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6797630 https://reactome.org/PathwayBrowser/#/R-BTA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6797653 https://reactome.org/PathwayBrowser/#/R-BTA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6797913 https://reactome.org/PathwayBrowser/#/R-BTA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6797955 https://reactome.org/PathwayBrowser/#/R-BTA-6797955 ALDH7A1 oxidises BETALD to BET IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6799545 https://reactome.org/PathwayBrowser/#/R-BTA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-6799581 https://reactome.org/PathwayBrowser/#/R-BTA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6799604 https://reactome.org/PathwayBrowser/#/R-BTA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6799695 https://reactome.org/PathwayBrowser/#/R-BTA-6799695 GPX5,6 reduce H2O2 to H2O IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6799977 https://reactome.org/PathwayBrowser/#/R-BTA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6800198 https://reactome.org/PathwayBrowser/#/R-BTA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6800200 https://reactome.org/PathwayBrowser/#/R-BTA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6800299 https://reactome.org/PathwayBrowser/#/R-BTA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6801462 https://reactome.org/PathwayBrowser/#/R-BTA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-6803753 https://reactome.org/PathwayBrowser/#/R-BTA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6803789 https://reactome.org/PathwayBrowser/#/R-BTA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6805650 https://reactome.org/PathwayBrowser/#/R-BTA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6807008 https://reactome.org/PathwayBrowser/#/R-BTA-6807008 PTPRJ dephosphorylates MET IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6807027 https://reactome.org/PathwayBrowser/#/R-BTA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6807118 https://reactome.org/PathwayBrowser/#/R-BTA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6807206 https://reactome.org/PathwayBrowser/#/R-BTA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-6809263 https://reactome.org/PathwayBrowser/#/R-BTA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6809320 https://reactome.org/PathwayBrowser/#/R-BTA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6809325 https://reactome.org/PathwayBrowser/#/R-BTA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6809720 https://reactome.org/PathwayBrowser/#/R-BTA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6809777 https://reactome.org/PathwayBrowser/#/R-BTA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6809778 https://reactome.org/PathwayBrowser/#/R-BTA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-6810410 https://reactome.org/PathwayBrowser/#/R-BTA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6810464 https://reactome.org/PathwayBrowser/#/R-BTA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-6810472 https://reactome.org/PathwayBrowser/#/R-BTA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6813720 https://reactome.org/PathwayBrowser/#/R-BTA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6813740 https://reactome.org/PathwayBrowser/#/R-BTA-6813740 GDE1 hydrolyzes GroPIns IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-6814254 https://reactome.org/PathwayBrowser/#/R-BTA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-6814797 https://reactome.org/PathwayBrowser/#/R-BTA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-69199 https://reactome.org/PathwayBrowser/#/R-BTA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70262 https://reactome.org/PathwayBrowser/#/R-BTA-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70479 https://reactome.org/PathwayBrowser/#/R-BTA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70494 https://reactome.org/PathwayBrowser/#/R-BTA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70569 https://reactome.org/PathwayBrowser/#/R-BTA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70609 https://reactome.org/PathwayBrowser/#/R-BTA-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70785 https://reactome.org/PathwayBrowser/#/R-BTA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70870 https://reactome.org/PathwayBrowser/#/R-BTA-70870 ECHS1 hydrates methacrylyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70903 https://reactome.org/PathwayBrowser/#/R-BTA-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-70906 https://reactome.org/PathwayBrowser/#/R-BTA-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-70982 https://reactome.org/PathwayBrowser/#/R-BTA-70982 FH tetramer hydrates fumarate to L-malate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71146 https://reactome.org/PathwayBrowser/#/R-BTA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71296 https://reactome.org/PathwayBrowser/#/R-BTA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71660 https://reactome.org/PathwayBrowser/#/R-BTA-71660 Enolase dimers dehydrates 2PG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71676 https://reactome.org/PathwayBrowser/#/R-BTA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-71732 https://reactome.org/PathwayBrowser/#/R-BTA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-71825 https://reactome.org/PathwayBrowser/#/R-BTA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73608 https://reactome.org/PathwayBrowser/#/R-BTA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73797 https://reactome.org/PathwayBrowser/#/R-BTA-73797 FAICAR => IMP + H2O IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-73815 https://reactome.org/PathwayBrowser/#/R-BTA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74059 https://reactome.org/PathwayBrowser/#/R-BTA-74059 PDE6 hydrolyses cGMP to GMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74241 https://reactome.org/PathwayBrowser/#/R-BTA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74248 https://reactome.org/PathwayBrowser/#/R-BTA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74733 https://reactome.org/PathwayBrowser/#/R-BTA-74733 Insulin receptor de-phosphorylation IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-74948 https://reactome.org/PathwayBrowser/#/R-BTA-74948 PP2A dephosphorylates p-RHO to RHO IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-75899 https://reactome.org/PathwayBrowser/#/R-BTA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-76590 https://reactome.org/PathwayBrowser/#/R-BTA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77256 https://reactome.org/PathwayBrowser/#/R-BTA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77277 https://reactome.org/PathwayBrowser/#/R-BTA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77301 https://reactome.org/PathwayBrowser/#/R-BTA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77314 https://reactome.org/PathwayBrowser/#/R-BTA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77325 https://reactome.org/PathwayBrowser/#/R-BTA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77333 https://reactome.org/PathwayBrowser/#/R-BTA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-77344 https://reactome.org/PathwayBrowser/#/R-BTA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-77614 https://reactome.org/PathwayBrowser/#/R-BTA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-77615 https://reactome.org/PathwayBrowser/#/R-BTA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-83677 https://reactome.org/PathwayBrowser/#/R-BTA-83677 C4 deamination of cytidine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-870437 https://reactome.org/PathwayBrowser/#/R-BTA-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8848053 https://reactome.org/PathwayBrowser/#/R-BTA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8848215 https://reactome.org/PathwayBrowser/#/R-BTA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8848338 https://reactome.org/PathwayBrowser/#/R-BTA-8848338 PNPLA4 hydrolyzes TAG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8848355 https://reactome.org/PathwayBrowser/#/R-BTA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8848484 https://reactome.org/PathwayBrowser/#/R-BTA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8849435 https://reactome.org/PathwayBrowser/#/R-BTA-8849435 PTPN1 dephosphorylates PTK6 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8849857 https://reactome.org/PathwayBrowser/#/R-BTA-8849857 KLK5 cleaves and activates CELA2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8849969 https://reactome.org/PathwayBrowser/#/R-BTA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8850594 https://reactome.org/PathwayBrowser/#/R-BTA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8850831 https://reactome.org/PathwayBrowser/#/R-BTA-8850831 KLK5 cleaves and activates KLK8 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-2022884 H2O [Golgi lumen] R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-2022884 H2O [Golgi lumen] R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8852200 https://reactome.org/PathwayBrowser/#/R-BTA-8852200 Inactivation of LCK by PTPN22 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8853379 https://reactome.org/PathwayBrowser/#/R-BTA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-8853686 https://reactome.org/PathwayBrowser/#/R-BTA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8854173 https://reactome.org/PathwayBrowser/#/R-BTA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8854255 https://reactome.org/PathwayBrowser/#/R-BTA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8854329 https://reactome.org/PathwayBrowser/#/R-BTA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8854604 https://reactome.org/PathwayBrowser/#/R-BTA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8854612 https://reactome.org/PathwayBrowser/#/R-BTA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8855381 https://reactome.org/PathwayBrowser/#/R-BTA-8855381 PTPN22 dephosphorylates ZAP70 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8855490 https://reactome.org/PathwayBrowser/#/R-BTA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8855825 https://reactome.org/PathwayBrowser/#/R-BTA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-8856951 https://reactome.org/PathwayBrowser/#/R-BTA-8856951 PP2A demethylation by PPME1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-8862184 https://reactome.org/PathwayBrowser/#/R-BTA-8862184 USP48 cleaves polyubiquitin IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8862320 https://reactome.org/PathwayBrowser/#/R-BTA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8863804 https://reactome.org/PathwayBrowser/#/R-BTA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8864036 https://reactome.org/PathwayBrowser/#/R-BTA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8864125 https://reactome.org/PathwayBrowser/#/R-BTA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-8865667 https://reactome.org/PathwayBrowser/#/R-BTA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8866405 https://reactome.org/PathwayBrowser/#/R-BTA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8866542 https://reactome.org/PathwayBrowser/#/R-BTA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8867047 https://reactome.org/PathwayBrowser/#/R-BTA-8867047 PTPN3 dephosphorylates EPS15 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-8867344 https://reactome.org/PathwayBrowser/#/R-BTA-8867344 OMA1 hydrolyses OPA1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8867658 https://reactome.org/PathwayBrowser/#/R-BTA-8867658 PTPN3 dephosphorylates MAPK12 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8868648 https://reactome.org/PathwayBrowser/#/R-BTA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8868658 https://reactome.org/PathwayBrowser/#/R-BTA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8868661 https://reactome.org/PathwayBrowser/#/R-BTA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8869206 https://reactome.org/PathwayBrowser/#/R-BTA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8869456 https://reactome.org/PathwayBrowser/#/R-BTA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8869506 https://reactome.org/PathwayBrowser/#/R-BTA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8874435 https://reactome.org/PathwayBrowser/#/R-BTA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8875443 https://reactome.org/PathwayBrowser/#/R-BTA-8875443 USP8 deubiquitinates LRIG1 IEA Bos taurus 15377 R-ALL-5668574 H2O [melanosome lumen] R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-8878654 https://reactome.org/PathwayBrowser/#/R-BTA-8878654 ACP6 hydrolyses MYS-LPA IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8878787 https://reactome.org/PathwayBrowser/#/R-BTA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8932633 https://reactome.org/PathwayBrowser/#/R-BTA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8933328 https://reactome.org/PathwayBrowser/#/R-BTA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Bos taurus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-893596 https://reactome.org/PathwayBrowser/#/R-BTA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8937442 https://reactome.org/PathwayBrowser/#/R-BTA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-8937767 https://reactome.org/PathwayBrowser/#/R-BTA-8937767 PTPN11 dephosphorylates RUNX1 IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8940074 https://reactome.org/PathwayBrowser/#/R-BTA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8940388 https://reactome.org/PathwayBrowser/#/R-BTA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8943279 https://reactome.org/PathwayBrowser/#/R-BTA-8943279 GGT dimers hydrolyse GSH IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8952137 https://reactome.org/PathwayBrowser/#/R-BTA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8952251 https://reactome.org/PathwayBrowser/#/R-BTA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-8952903 https://reactome.org/PathwayBrowser/#/R-BTA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8953339 https://reactome.org/PathwayBrowser/#/R-BTA-8953339 DNPH1 hydrolyses dGMP IEA Bos taurus 15377 R-ALL-2022884 H2O [Golgi lumen] R-BTA-8953499 https://reactome.org/PathwayBrowser/#/R-BTA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Bos taurus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-BTA-8954398 https://reactome.org/PathwayBrowser/#/R-BTA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8955794 https://reactome.org/PathwayBrowser/#/R-BTA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-8955817 https://reactome.org/PathwayBrowser/#/R-BTA-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8979996 https://reactome.org/PathwayBrowser/#/R-BTA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-8980228 https://reactome.org/PathwayBrowser/#/R-BTA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8981637 https://reactome.org/PathwayBrowser/#/R-BTA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8985594 https://reactome.org/PathwayBrowser/#/R-BTA-8985594 MYO9B inactivates RHOA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-8986083 https://reactome.org/PathwayBrowser/#/R-BTA-8986083 USP33 deubiquitinates ROBO1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-9008822 https://reactome.org/PathwayBrowser/#/R-BTA-9008822 PPM1D dephosphorylates RUNX2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9013111 https://reactome.org/PathwayBrowser/#/R-BTA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9013144 https://reactome.org/PathwayBrowser/#/R-BTA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9013161 https://reactome.org/PathwayBrowser/#/R-BTA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9013437 https://reactome.org/PathwayBrowser/#/R-BTA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9014295 https://reactome.org/PathwayBrowser/#/R-BTA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9014434 https://reactome.org/PathwayBrowser/#/R-BTA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9014641 https://reactome.org/PathwayBrowser/#/R-BTA-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9017488 https://reactome.org/PathwayBrowser/#/R-BTA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018745 https://reactome.org/PathwayBrowser/#/R-BTA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018806 https://reactome.org/PathwayBrowser/#/R-BTA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018814 https://reactome.org/PathwayBrowser/#/R-BTA-9018814 RHOT1 hydrolyzes GTP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018826 https://reactome.org/PathwayBrowser/#/R-BTA-9018826 RHOT2 hydrolyzes GTP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018862 https://reactome.org/PathwayBrowser/#/R-BTA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018868 https://reactome.org/PathwayBrowser/#/R-BTA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018877 https://reactome.org/PathwayBrowser/#/R-BTA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9018895 https://reactome.org/PathwayBrowser/#/R-BTA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020252 https://reactome.org/PathwayBrowser/#/R-BTA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020253 https://reactome.org/PathwayBrowser/#/R-BTA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020257 https://reactome.org/PathwayBrowser/#/R-BTA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020258 https://reactome.org/PathwayBrowser/#/R-BTA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020270 https://reactome.org/PathwayBrowser/#/R-BTA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020271 https://reactome.org/PathwayBrowser/#/R-BTA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9020273 https://reactome.org/PathwayBrowser/#/R-BTA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9024890 https://reactome.org/PathwayBrowser/#/R-BTA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9024993 https://reactome.org/PathwayBrowser/#/R-BTA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9033491 https://reactome.org/PathwayBrowser/#/R-BTA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Bos taurus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-BTA-9033520 https://reactome.org/PathwayBrowser/#/R-BTA-9033520 TYSND1 cleaves TYSND1 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9036727 https://reactome.org/PathwayBrowser/#/R-BTA-9036727 GAA hydrolyzes lysosomal glycogen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-936883 https://reactome.org/PathwayBrowser/#/R-BTA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-936897 https://reactome.org/PathwayBrowser/#/R-BTA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-939763 https://reactome.org/PathwayBrowser/#/R-BTA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-947531 https://reactome.org/PathwayBrowser/#/R-BTA-947531 Molybdenum ion transfer onto molybdopterin IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-947535 https://reactome.org/PathwayBrowser/#/R-BTA-947535 Cyclisation of GTP to precursor Z IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-947591 https://reactome.org/PathwayBrowser/#/R-BTA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9624893 https://reactome.org/PathwayBrowser/#/R-BTA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9629675 https://reactome.org/PathwayBrowser/#/R-BTA-9629675 PDE3A hydrolyses cAMP to AMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9635739 https://reactome.org/PathwayBrowser/#/R-BTA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9638075 https://reactome.org/PathwayBrowser/#/R-BTA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9638076 https://reactome.org/PathwayBrowser/#/R-BTA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9638078 https://reactome.org/PathwayBrowser/#/R-BTA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9638120 https://reactome.org/PathwayBrowser/#/R-BTA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9644869 https://reactome.org/PathwayBrowser/#/R-BTA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9647994 https://reactome.org/PathwayBrowser/#/R-BTA-9647994 RAS proteins are depalmitoylated IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-965067 https://reactome.org/PathwayBrowser/#/R-BTA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9653514 https://reactome.org/PathwayBrowser/#/R-BTA-9653514 USP17L2 deubiquitinates RCE1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9656891 https://reactome.org/PathwayBrowser/#/R-BTA-9656891 OPN1SW binds 11cRAL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9656893 https://reactome.org/PathwayBrowser/#/R-BTA-9656893 OPN1MW binds 11cRAL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9658445 https://reactome.org/PathwayBrowser/#/R-BTA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9659680 https://reactome.org/PathwayBrowser/#/R-BTA-9659680 ABCB1 transports xenobiotics out of the cell IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9661417 https://reactome.org/PathwayBrowser/#/R-BTA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9667952 https://reactome.org/PathwayBrowser/#/R-BTA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9668419 https://reactome.org/PathwayBrowser/#/R-BTA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-9673053 https://reactome.org/PathwayBrowser/#/R-BTA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-9673054 https://reactome.org/PathwayBrowser/#/R-BTA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9674127 https://reactome.org/PathwayBrowser/#/R-BTA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-9686524 https://reactome.org/PathwayBrowser/#/R-BTA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9693282 https://reactome.org/PathwayBrowser/#/R-BTA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9698408 https://reactome.org/PathwayBrowser/#/R-BTA-9698408 PTPRJ dephosphorylates active FLT3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9700200 https://reactome.org/PathwayBrowser/#/R-BTA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9701507 https://reactome.org/PathwayBrowser/#/R-BTA-9701507 PTPN6 dephosphorylates JAK3 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-9701565 https://reactome.org/PathwayBrowser/#/R-BTA-9701565 HDACs deacetylate p-STAT3 dimers IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9705507 https://reactome.org/PathwayBrowser/#/R-BTA-9705507 PDE3B hydrolyses cAMP to AMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9706399 https://reactome.org/PathwayBrowser/#/R-BTA-9706399 RHOBTB3 hydrolyzes ATP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9708261 https://reactome.org/PathwayBrowser/#/R-BTA-9708261 PDE4A hydrolyses cAMP to AMP IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9727567 https://reactome.org/PathwayBrowser/#/R-BTA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9750546 https://reactome.org/PathwayBrowser/#/R-BTA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9750555 https://reactome.org/PathwayBrowser/#/R-BTA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9750617 https://reactome.org/PathwayBrowser/#/R-BTA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9750656 https://reactome.org/PathwayBrowser/#/R-BTA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9750942 https://reactome.org/PathwayBrowser/#/R-BTA-9750942 USP14 deubiquitinates NLRC5 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753278 https://reactome.org/PathwayBrowser/#/R-BTA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753280 https://reactome.org/PathwayBrowser/#/R-BTA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753283 https://reactome.org/PathwayBrowser/#/R-BTA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753284 https://reactome.org/PathwayBrowser/#/R-BTA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753632 https://reactome.org/PathwayBrowser/#/R-BTA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753634 https://reactome.org/PathwayBrowser/#/R-BTA-9753634 GGT dimers hydrolyse APAP-SG IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9753944 https://reactome.org/PathwayBrowser/#/R-BTA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9754964 https://reactome.org/PathwayBrowser/#/R-BTA-9754964 ADA deamidates RBV IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9755030 https://reactome.org/PathwayBrowser/#/R-BTA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9755078 https://reactome.org/PathwayBrowser/#/R-BTA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-975593 https://reactome.org/PathwayBrowser/#/R-BTA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-BTA-975594 https://reactome.org/PathwayBrowser/#/R-BTA-975594 PLB1 hydrolyses RPALM to atROL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9759206 https://reactome.org/PathwayBrowser/#/R-BTA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9759454 https://reactome.org/PathwayBrowser/#/R-BTA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9759461 https://reactome.org/PathwayBrowser/#/R-BTA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-977324 https://reactome.org/PathwayBrowser/#/R-BTA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9794120 https://reactome.org/PathwayBrowser/#/R-BTA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9794572 https://reactome.org/PathwayBrowser/#/R-BTA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-9825772 https://reactome.org/PathwayBrowser/#/R-BTA-9825772 SIRT1 deacetylates HINT1 dimer IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-983144 https://reactome.org/PathwayBrowser/#/R-BTA-983144 Transport of Antigen peptide in to ER IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-983422 https://reactome.org/PathwayBrowser/#/R-BTA-983422 Disassembly of COPII coated vesicle IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9837419 https://reactome.org/PathwayBrowser/#/R-BTA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9838004 https://reactome.org/PathwayBrowser/#/R-BTA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9838081 https://reactome.org/PathwayBrowser/#/R-BTA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9838289 https://reactome.org/PathwayBrowser/#/R-BTA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9839059 https://reactome.org/PathwayBrowser/#/R-BTA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Bos taurus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-BTA-9839072 https://reactome.org/PathwayBrowser/#/R-BTA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9839105 https://reactome.org/PathwayBrowser/#/R-BTA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Bos taurus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-BTA-9839110 https://reactome.org/PathwayBrowser/#/R-BTA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9839113 https://reactome.org/PathwayBrowser/#/R-BTA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Bos taurus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-BTA-9840408 https://reactome.org/PathwayBrowser/#/R-BTA-9840408 OMA1 cleaves DELE1 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9840795 https://reactome.org/PathwayBrowser/#/R-BTA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9840833 https://reactome.org/PathwayBrowser/#/R-BTA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9840884 https://reactome.org/PathwayBrowser/#/R-BTA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9840949 https://reactome.org/PathwayBrowser/#/R-BTA-9840949 ARSA removes sulfate from SM3 IEA Bos taurus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-BTA-9841189 https://reactome.org/PathwayBrowser/#/R-BTA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9841847 https://reactome.org/PathwayBrowser/#/R-BTA-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9853385 https://reactome.org/PathwayBrowser/#/R-BTA-9853385 PPP1CC dephosphorylates PLK1 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9861626 https://reactome.org/PathwayBrowser/#/R-BTA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9861725 https://reactome.org/PathwayBrowser/#/R-BTA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9865167 https://reactome.org/PathwayBrowser/#/R-BTA-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9865216 https://reactome.org/PathwayBrowser/#/R-BTA-9865216 PP2A dephosphorylates p-S585-PDE4D in p-S585-PDE4D:integrin alpha5:beta1:fibronectin TAS Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9865226 https://reactome.org/PathwayBrowser/#/R-BTA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9865751 https://reactome.org/PathwayBrowser/#/R-BTA-9865751 PDE4D in PDE4D:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP TAS Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9912636 https://reactome.org/PathwayBrowser/#/R-BTA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9912655 https://reactome.org/PathwayBrowser/#/R-BTA-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9912747 https://reactome.org/PathwayBrowser/#/R-BTA-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9912751 https://reactome.org/PathwayBrowser/#/R-BTA-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9915968 https://reactome.org/PathwayBrowser/#/R-BTA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9915971 https://reactome.org/PathwayBrowser/#/R-BTA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9915986 https://reactome.org/PathwayBrowser/#/R-BTA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-BTA-9915993 https://reactome.org/PathwayBrowser/#/R-BTA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9915994 https://reactome.org/PathwayBrowser/#/R-BTA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9915997 https://reactome.org/PathwayBrowser/#/R-BTA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-9916401 https://reactome.org/PathwayBrowser/#/R-BTA-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Bos taurus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-BTA-9929439 https://reactome.org/PathwayBrowser/#/R-BTA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-997309 https://reactome.org/PathwayBrowser/#/R-BTA-997309 Dephosphorylation of STAT1 by SHP2 IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-997311 https://reactome.org/PathwayBrowser/#/R-BTA-997311 Dephosphorylation of TYK2 by PTP1B IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-BTA-997314 https://reactome.org/PathwayBrowser/#/R-BTA-997314 Dephosphorylation of JAK1 by SHP1 IEA Bos taurus 15377 R-ALL-113518 H2O [nucleoplasm] R-BTA-997326 https://reactome.org/PathwayBrowser/#/R-BTA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Bos taurus 15377 R-ALL-29356 H2O [cytosol] R-CEL-109449 https://reactome.org/PathwayBrowser/#/R-CEL-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111742 https://reactome.org/PathwayBrowser/#/R-CEL-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111751 https://reactome.org/PathwayBrowser/#/R-CEL-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111804 https://reactome.org/PathwayBrowser/#/R-CEL-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111879 https://reactome.org/PathwayBrowser/#/R-CEL-111879 PIP2 hydrolysis IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111955 https://reactome.org/PathwayBrowser/#/R-CEL-111955 cAMP hydrolysis by Cam-PDE 1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-111962 https://reactome.org/PathwayBrowser/#/R-CEL-111962 PDE4A,C,D hydrolyse cAMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-112037 https://reactome.org/PathwayBrowser/#/R-CEL-112037 Inactivation of PLC beta IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1237129 https://reactome.org/PathwayBrowser/#/R-CEL-1237129 Acireductone is created IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1247910 https://reactome.org/PathwayBrowser/#/R-CEL-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1247935 https://reactome.org/PathwayBrowser/#/R-CEL-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-1363274 https://reactome.org/PathwayBrowser/#/R-CEL-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-1363276 https://reactome.org/PathwayBrowser/#/R-CEL-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1369065 https://reactome.org/PathwayBrowser/#/R-CEL-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1454916 https://reactome.org/PathwayBrowser/#/R-CEL-1454916 The ABCC family mediates organic anion transport IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1467466 https://reactome.org/PathwayBrowser/#/R-CEL-1467466 ABCA4 mediates atRAL transport IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1474146 https://reactome.org/PathwayBrowser/#/R-CEL-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482604 https://reactome.org/PathwayBrowser/#/R-CEL-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482656 https://reactome.org/PathwayBrowser/#/R-CEL-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482679 https://reactome.org/PathwayBrowser/#/R-CEL-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482776 https://reactome.org/PathwayBrowser/#/R-CEL-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482777 https://reactome.org/PathwayBrowser/#/R-CEL-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482811 https://reactome.org/PathwayBrowser/#/R-CEL-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482816 https://reactome.org/PathwayBrowser/#/R-CEL-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482856 https://reactome.org/PathwayBrowser/#/R-CEL-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482868 https://reactome.org/PathwayBrowser/#/R-CEL-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482884 https://reactome.org/PathwayBrowser/#/R-CEL-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482887 https://reactome.org/PathwayBrowser/#/R-CEL-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482900 https://reactome.org/PathwayBrowser/#/R-CEL-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1482907 https://reactome.org/PathwayBrowser/#/R-CEL-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1483182 https://reactome.org/PathwayBrowser/#/R-CEL-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1483203 https://reactome.org/PathwayBrowser/#/R-CEL-1483203 PA is dephosphorylated to DAG by LPIN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-159425 https://reactome.org/PathwayBrowser/#/R-CEL-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602368 https://reactome.org/PathwayBrowser/#/R-CEL-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602374 https://reactome.org/PathwayBrowser/#/R-CEL-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602377 https://reactome.org/PathwayBrowser/#/R-CEL-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602398 https://reactome.org/PathwayBrowser/#/R-CEL-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602399 https://reactome.org/PathwayBrowser/#/R-CEL-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602417 https://reactome.org/PathwayBrowser/#/R-CEL-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-1602446 https://reactome.org/PathwayBrowser/#/R-CEL-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605591 https://reactome.org/PathwayBrowser/#/R-CEL-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605595 https://reactome.org/PathwayBrowser/#/R-CEL-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605624 https://reactome.org/PathwayBrowser/#/R-CEL-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605632 https://reactome.org/PathwayBrowser/#/R-CEL-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605736 https://reactome.org/PathwayBrowser/#/R-CEL-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1606312 https://reactome.org/PathwayBrowser/#/R-CEL-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1606564 https://reactome.org/PathwayBrowser/#/R-CEL-1606564 GALC hydrolyzes GalCer IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1606602 https://reactome.org/PathwayBrowser/#/R-CEL-1606602 ASAH1 hydrolyzes ceramide IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1606789 https://reactome.org/PathwayBrowser/#/R-CEL-1606789 ARSB hydrolyses DS IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1614524 https://reactome.org/PathwayBrowser/#/R-CEL-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1614583 https://reactome.org/PathwayBrowser/#/R-CEL-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to pyruvate and H2S IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-162425 https://reactome.org/PathwayBrowser/#/R-CEL-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-162857 https://reactome.org/PathwayBrowser/#/R-CEL-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1630306 https://reactome.org/PathwayBrowser/#/R-CEL-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1638053 https://reactome.org/PathwayBrowser/#/R-CEL-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-164832 https://reactome.org/PathwayBrowser/#/R-CEL-164832 ATPase synthesizes ATP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675795 https://reactome.org/PathwayBrowser/#/R-CEL-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675824 https://reactome.org/PathwayBrowser/#/R-CEL-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675836 https://reactome.org/PathwayBrowser/#/R-CEL-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675949 https://reactome.org/PathwayBrowser/#/R-CEL-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675988 https://reactome.org/PathwayBrowser/#/R-CEL-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1675994 https://reactome.org/PathwayBrowser/#/R-CEL-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676065 https://reactome.org/PathwayBrowser/#/R-CEL-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676105 https://reactome.org/PathwayBrowser/#/R-CEL-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676114 https://reactome.org/PathwayBrowser/#/R-CEL-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676124 https://reactome.org/PathwayBrowser/#/R-CEL-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676141 https://reactome.org/PathwayBrowser/#/R-CEL-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676149 https://reactome.org/PathwayBrowser/#/R-CEL-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676162 https://reactome.org/PathwayBrowser/#/R-CEL-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676164 https://reactome.org/PathwayBrowser/#/R-CEL-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676177 https://reactome.org/PathwayBrowser/#/R-CEL-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1676203 https://reactome.org/PathwayBrowser/#/R-CEL-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1678742 https://reactome.org/PathwayBrowser/#/R-CEL-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1678854 https://reactome.org/PathwayBrowser/#/R-CEL-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-170153 https://reactome.org/PathwayBrowser/#/R-CEL-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-170158 https://reactome.org/PathwayBrowser/#/R-CEL-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-170161 https://reactome.org/PathwayBrowser/#/R-CEL-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-174110 https://reactome.org/PathwayBrowser/#/R-CEL-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-174401 https://reactome.org/PathwayBrowser/#/R-CEL-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-176606 https://reactome.org/PathwayBrowser/#/R-CEL-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1793207 https://reactome.org/PathwayBrowser/#/R-CEL-1793207 ARSB hydrolyses C4S/C6S chains IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-1793209 https://reactome.org/PathwayBrowser/#/R-CEL-1793209 HYAL1 hydrolyses Chondroitin chains IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855154 https://reactome.org/PathwayBrowser/#/R-CEL-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855165 https://reactome.org/PathwayBrowser/#/R-CEL-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855166 https://reactome.org/PathwayBrowser/#/R-CEL-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855174 https://reactome.org/PathwayBrowser/#/R-CEL-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855177 https://reactome.org/PathwayBrowser/#/R-CEL-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855180 https://reactome.org/PathwayBrowser/#/R-CEL-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855198 https://reactome.org/PathwayBrowser/#/R-CEL-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855202 https://reactome.org/PathwayBrowser/#/R-CEL-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855205 https://reactome.org/PathwayBrowser/#/R-CEL-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855210 https://reactome.org/PathwayBrowser/#/R-CEL-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855211 https://reactome.org/PathwayBrowser/#/R-CEL-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855213 https://reactome.org/PathwayBrowser/#/R-CEL-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855214 https://reactome.org/PathwayBrowser/#/R-CEL-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855218 https://reactome.org/PathwayBrowser/#/R-CEL-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855221 https://reactome.org/PathwayBrowser/#/R-CEL-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1855222 https://reactome.org/PathwayBrowser/#/R-CEL-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1861788 https://reactome.org/PathwayBrowser/#/R-CEL-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-1861789 https://reactome.org/PathwayBrowser/#/R-CEL-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-188979 https://reactome.org/PathwayBrowser/#/R-CEL-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-189053 https://reactome.org/PathwayBrowser/#/R-CEL-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-189062 https://reactome.org/PathwayBrowser/#/R-CEL-189062 lactose + H2O => D-glucose + D-galactose IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-189069 https://reactome.org/PathwayBrowser/#/R-CEL-189069 sucrose + H2O => glucose + fructose IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-189102 https://reactome.org/PathwayBrowser/#/R-CEL-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-191101 https://reactome.org/PathwayBrowser/#/R-CEL-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-191108 https://reactome.org/PathwayBrowser/#/R-CEL-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-191114 https://reactome.org/PathwayBrowser/#/R-CEL-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-191116 https://reactome.org/PathwayBrowser/#/R-CEL-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-192331 https://reactome.org/PathwayBrowser/#/R-CEL-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-192417 https://reactome.org/PathwayBrowser/#/R-CEL-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-192425 https://reactome.org/PathwayBrowser/#/R-CEL-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-192430 https://reactome.org/PathwayBrowser/#/R-CEL-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-193385 https://reactome.org/PathwayBrowser/#/R-CEL-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-193535 https://reactome.org/PathwayBrowser/#/R-CEL-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193711 https://reactome.org/PathwayBrowser/#/R-CEL-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193727 https://reactome.org/PathwayBrowser/#/R-CEL-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193743 https://reactome.org/PathwayBrowser/#/R-CEL-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-193766 https://reactome.org/PathwayBrowser/#/R-CEL-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-196950 https://reactome.org/PathwayBrowser/#/R-CEL-196950 2xTRAP hydrolyzes FMN to RIB IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-197186 https://reactome.org/PathwayBrowser/#/R-CEL-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-199456 https://reactome.org/PathwayBrowser/#/R-CEL-199456 PTEN dephosphorylates PIP3 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-199959 https://reactome.org/PathwayBrowser/#/R-CEL-199959 ERKs are inactivated by protein phosphatase 2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-200661 https://reactome.org/PathwayBrowser/#/R-CEL-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-200740 https://reactome.org/PathwayBrowser/#/R-CEL-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-201035 https://reactome.org/PathwayBrowser/#/R-CEL-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022368 https://reactome.org/PathwayBrowser/#/R-CEL-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022381 https://reactome.org/PathwayBrowser/#/R-CEL-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022396 https://reactome.org/PathwayBrowser/#/R-CEL-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022398 https://reactome.org/PathwayBrowser/#/R-CEL-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022399 https://reactome.org/PathwayBrowser/#/R-CEL-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022403 https://reactome.org/PathwayBrowser/#/R-CEL-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022405 https://reactome.org/PathwayBrowser/#/R-CEL-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2022412 https://reactome.org/PathwayBrowser/#/R-CEL-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-ALL-2022884 H2O [Golgi lumen] R-CEL-2022887 https://reactome.org/PathwayBrowser/#/R-CEL-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2023971 https://reactome.org/PathwayBrowser/#/R-CEL-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2023973 https://reactome.org/PathwayBrowser/#/R-CEL-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2028294 https://reactome.org/PathwayBrowser/#/R-CEL-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2029471 https://reactome.org/PathwayBrowser/#/R-CEL-2029471 Hydrolysis of PC to PA by PLD IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2029475 https://reactome.org/PathwayBrowser/#/R-CEL-2029475 Production of AA by iPLA2 upon FCGR activation IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-203797 https://reactome.org/PathwayBrowser/#/R-CEL-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-204169 https://reactome.org/PathwayBrowser/#/R-CEL-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046088 https://reactome.org/PathwayBrowser/#/R-CEL-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046094 https://reactome.org/PathwayBrowser/#/R-CEL-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2065355 https://reactome.org/PathwayBrowser/#/R-CEL-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-2065357 https://reactome.org/PathwayBrowser/#/R-CEL-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-2066778 https://reactome.org/PathwayBrowser/#/R-CEL-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-2066779 https://reactome.org/PathwayBrowser/#/R-CEL-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2090038 https://reactome.org/PathwayBrowser/#/R-CEL-2090038 NAGLU hydrolyses heparan chain(2) IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2090079 https://reactome.org/PathwayBrowser/#/R-CEL-2090079 GLB1 hydrolyses linker chain(2) IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-209055 https://reactome.org/PathwayBrowser/#/R-CEL-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2105001 https://reactome.org/PathwayBrowser/#/R-CEL-2105001 HEXA cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2160874 https://reactome.org/PathwayBrowser/#/R-CEL-2160874 HYAL1 hydrolyses (HA)50 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161195 https://reactome.org/PathwayBrowser/#/R-CEL-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161959 https://reactome.org/PathwayBrowser/#/R-CEL-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2161999 https://reactome.org/PathwayBrowser/#/R-CEL-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-2162187 https://reactome.org/PathwayBrowser/#/R-CEL-2162187 COQ6 hydroxylates DHB IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2162225 https://reactome.org/PathwayBrowser/#/R-CEL-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2162226 https://reactome.org/PathwayBrowser/#/R-CEL-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-2162227 https://reactome.org/PathwayBrowser/#/R-CEL-2162227 GUSB tetramer hydrolyses (HA)2 IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2393939 https://reactome.org/PathwayBrowser/#/R-CEL-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-2393954 https://reactome.org/PathwayBrowser/#/R-CEL-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2454118 https://reactome.org/PathwayBrowser/#/R-CEL-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2465924 https://reactome.org/PathwayBrowser/#/R-CEL-2465924 OPN1LW binds 11cRAL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2466085 https://reactome.org/PathwayBrowser/#/R-CEL-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2632521 https://reactome.org/PathwayBrowser/#/R-CEL-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-265783 https://reactome.org/PathwayBrowser/#/R-CEL-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-266046 https://reactome.org/PathwayBrowser/#/R-CEL-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-266070 https://reactome.org/PathwayBrowser/#/R-CEL-266070 LTC4 is exported from the cytosol by ABCC1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-266072 https://reactome.org/PathwayBrowser/#/R-CEL-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-2995330 https://reactome.org/PathwayBrowser/#/R-CEL-2995330 COX10 transforms heme to heme O IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-2995334 https://reactome.org/PathwayBrowser/#/R-CEL-2995334 COX15 transforms heme O to heme A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-2995388 https://reactome.org/PathwayBrowser/#/R-CEL-2995388 PP2A dephosphorylates BANF1 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-3002811 https://reactome.org/PathwayBrowser/#/R-CEL-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3095901 https://reactome.org/PathwayBrowser/#/R-CEL-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-3322995 https://reactome.org/PathwayBrowser/#/R-CEL-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3341343 https://reactome.org/PathwayBrowser/#/R-CEL-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-3341397 https://reactome.org/PathwayBrowser/#/R-CEL-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3343700 https://reactome.org/PathwayBrowser/#/R-CEL-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-372519 https://reactome.org/PathwayBrowser/#/R-CEL-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3781011 https://reactome.org/PathwayBrowser/#/R-CEL-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-3781018 https://reactome.org/PathwayBrowser/#/R-CEL-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-380949 https://reactome.org/PathwayBrowser/#/R-CEL-380949 AMPK is dephosphorylated IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-382560 https://reactome.org/PathwayBrowser/#/R-CEL-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-382575 https://reactome.org/PathwayBrowser/#/R-CEL-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-383190 https://reactome.org/PathwayBrowser/#/R-CEL-383190 HCO3- transport through ion channel IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-389986 https://reactome.org/PathwayBrowser/#/R-CEL-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-390252 https://reactome.org/PathwayBrowser/#/R-CEL-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-390329 https://reactome.org/PathwayBrowser/#/R-CEL-390329 Dephosphorylation of AKT by PP2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-390393 https://reactome.org/PathwayBrowser/#/R-CEL-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-4093339 https://reactome.org/PathwayBrowser/#/R-CEL-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-416559 https://reactome.org/PathwayBrowser/#/R-CEL-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-418553 https://reactome.org/PathwayBrowser/#/R-CEL-418553 cAMP degradation by Phosphodiesterases IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-428205 https://reactome.org/PathwayBrowser/#/R-CEL-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-428231 https://reactome.org/PathwayBrowser/#/R-CEL-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-428690 https://reactome.org/PathwayBrowser/#/R-CEL-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-428696 https://reactome.org/PathwayBrowser/#/R-CEL-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-429860 https://reactome.org/PathwayBrowser/#/R-CEL-429860 DCP1-DCP2 complex decaps mRNA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-429961 https://reactome.org/PathwayBrowser/#/R-CEL-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-430028 https://reactome.org/PathwayBrowser/#/R-CEL-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-4419948 https://reactome.org/PathwayBrowser/#/R-CEL-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-445714 https://reactome.org/PathwayBrowser/#/R-CEL-445714 Aquaporin-3 passively transports water out of cell IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-445714 https://reactome.org/PathwayBrowser/#/R-CEL-445714 Aquaporin-3 passively transports water out of cell IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-449937 https://reactome.org/PathwayBrowser/#/R-CEL-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-452036 https://reactome.org/PathwayBrowser/#/R-CEL-452036 arginine + H2O => ornithine + urea [ARG2] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-507868 https://reactome.org/PathwayBrowser/#/R-CEL-507868 Aquaporins passively transport water into cells IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-507868 https://reactome.org/PathwayBrowser/#/R-CEL-507868 Aquaporins passively transport water into cells IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-507870 https://reactome.org/PathwayBrowser/#/R-CEL-507870 Aquaporins passively transport water out of cells IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-507870 https://reactome.org/PathwayBrowser/#/R-CEL-507870 Aquaporins passively transport water out of cells IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5221130 https://reactome.org/PathwayBrowser/#/R-CEL-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5223317 https://reactome.org/PathwayBrowser/#/R-CEL-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5251955 https://reactome.org/PathwayBrowser/#/R-CEL-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5251959 https://reactome.org/PathwayBrowser/#/R-CEL-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5251989 https://reactome.org/PathwayBrowser/#/R-CEL-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-5433072 https://reactome.org/PathwayBrowser/#/R-CEL-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5433074 https://reactome.org/PathwayBrowser/#/R-CEL-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-548843 https://reactome.org/PathwayBrowser/#/R-CEL-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5631885 https://reactome.org/PathwayBrowser/#/R-CEL-5631885 PRDX1 overoxidizes IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-5659861 https://reactome.org/PathwayBrowser/#/R-CEL-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Caenorhabditis elegans 15377 R-ALL-5668574 H2O [melanosome lumen] R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5672957 https://reactome.org/PathwayBrowser/#/R-CEL-5672957 PP2A dephosphorylates KSR1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5672961 https://reactome.org/PathwayBrowser/#/R-CEL-5672961 PP2A dephosphorylates inactive RAFs IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5675376 https://reactome.org/PathwayBrowser/#/R-CEL-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5675431 https://reactome.org/PathwayBrowser/#/R-CEL-5675431 PP2A dephosphorylates RAF1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5675433 https://reactome.org/PathwayBrowser/#/R-CEL-5675433 PP5 dephosphorylates RAF1 S338 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5676637 https://reactome.org/PathwayBrowser/#/R-CEL-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5678863 https://reactome.org/PathwayBrowser/#/R-CEL-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5679041 https://reactome.org/PathwayBrowser/#/R-CEL-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5682285 https://reactome.org/PathwayBrowser/#/R-CEL-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5683714 https://reactome.org/PathwayBrowser/#/R-CEL-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Caenorhabditis elegans 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-CEL-5684864 https://reactome.org/PathwayBrowser/#/R-CEL-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5687464 https://reactome.org/PathwayBrowser/#/R-CEL-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5687664 https://reactome.org/PathwayBrowser/#/R-CEL-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5688797 https://reactome.org/PathwayBrowser/#/R-CEL-5688797 ATXN3 family cleave Ub chains IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5689000 https://reactome.org/PathwayBrowser/#/R-CEL-5689000 AADAC deacetylates PHEN IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5689950 https://reactome.org/PathwayBrowser/#/R-CEL-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5690043 https://reactome.org/PathwayBrowser/#/R-CEL-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-5690066 https://reactome.org/PathwayBrowser/#/R-CEL-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5690157 https://reactome.org/PathwayBrowser/#/R-CEL-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5690159 https://reactome.org/PathwayBrowser/#/R-CEL-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5690319 https://reactome.org/PathwayBrowser/#/R-CEL-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-5690517 https://reactome.org/PathwayBrowser/#/R-CEL-5690517 PPT1 hydrolyses palmitoylated proteins IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5690808 https://reactome.org/PathwayBrowser/#/R-CEL-5690808 UCHL3, SENP8 cleave NEDD8 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5691381 https://reactome.org/PathwayBrowser/#/R-CEL-5691381 MYSM1 deubiquitinates Histone H2A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5691512 https://reactome.org/PathwayBrowser/#/R-CEL-5691512 APEH hydrolyses NAc-Ser-protein IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5692462 https://reactome.org/PathwayBrowser/#/R-CEL-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5692754 https://reactome.org/PathwayBrowser/#/R-CEL-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-5693724 https://reactome.org/PathwayBrowser/#/R-CEL-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5693742 https://reactome.org/PathwayBrowser/#/R-CEL-5693742 FAAH hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 15377 R-ALL-5693747 H2O [lipid droplet] R-CEL-5693751 https://reactome.org/PathwayBrowser/#/R-CEL-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5693783 https://reactome.org/PathwayBrowser/#/R-CEL-5693783 NAALADases hydrolyse NAAG IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-5693807 https://reactome.org/PathwayBrowser/#/R-CEL-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5694077 https://reactome.org/PathwayBrowser/#/R-CEL-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5694126 https://reactome.org/PathwayBrowser/#/R-CEL-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5694485 https://reactome.org/PathwayBrowser/#/R-CEL-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5694583 https://reactome.org/PathwayBrowser/#/R-CEL-5694583 ABHD4 hydrolyses NAPE IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5695964 https://reactome.org/PathwayBrowser/#/R-CEL-5695964 ABHD14B hydrolyses PNPB IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-5696197 https://reactome.org/PathwayBrowser/#/R-CEL-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696230 https://reactome.org/PathwayBrowser/#/R-CEL-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-5696408 https://reactome.org/PathwayBrowser/#/R-CEL-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-5696415 https://reactome.org/PathwayBrowser/#/R-CEL-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696564 https://reactome.org/PathwayBrowser/#/R-CEL-5696564 USP25 deubiquitinates DDX58 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696600 https://reactome.org/PathwayBrowser/#/R-CEL-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5696605 https://reactome.org/PathwayBrowser/#/R-CEL-5696605 USP12, USP26 deubiquitinate AR IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696627 https://reactome.org/PathwayBrowser/#/R-CEL-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-5696872 https://reactome.org/PathwayBrowser/#/R-CEL-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5696958 https://reactome.org/PathwayBrowser/#/R-CEL-5696958 USP44 deubiquitinates CDC20 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-5697009 https://reactome.org/PathwayBrowser/#/R-CEL-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6781764 https://reactome.org/PathwayBrowser/#/R-CEL-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-6782069 https://reactome.org/PathwayBrowser/#/R-CEL-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6784959 https://reactome.org/PathwayBrowser/#/R-CEL-6784959 BPHL hydrolyses VACV to ACV IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-6786652 https://reactome.org/PathwayBrowser/#/R-CEL-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6787632 https://reactome.org/PathwayBrowser/#/R-CEL-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6788295 https://reactome.org/PathwayBrowser/#/R-CEL-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6788912 https://reactome.org/PathwayBrowser/#/R-CEL-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Caenorhabditis elegans 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6797627 https://reactome.org/PathwayBrowser/#/R-CEL-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-6797630 https://reactome.org/PathwayBrowser/#/R-CEL-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-6797653 https://reactome.org/PathwayBrowser/#/R-CEL-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-6797955 https://reactome.org/PathwayBrowser/#/R-CEL-6797955 ALDH7A1 oxidises BETALD to BET IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-6799581 https://reactome.org/PathwayBrowser/#/R-CEL-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6799604 https://reactome.org/PathwayBrowser/#/R-CEL-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-6799695 https://reactome.org/PathwayBrowser/#/R-CEL-6799695 GPX5,6 reduce H2O2 to H2O IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-6803753 https://reactome.org/PathwayBrowser/#/R-CEL-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6803789 https://reactome.org/PathwayBrowser/#/R-CEL-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-6805650 https://reactome.org/PathwayBrowser/#/R-CEL-6805650 MTA2-NuRD complex deacetylates TP53 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6807008 https://reactome.org/PathwayBrowser/#/R-CEL-6807008 PTPRJ dephosphorylates MET IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-6807118 https://reactome.org/PathwayBrowser/#/R-CEL-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6807206 https://reactome.org/PathwayBrowser/#/R-CEL-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-6809263 https://reactome.org/PathwayBrowser/#/R-CEL-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6809320 https://reactome.org/PathwayBrowser/#/R-CEL-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6809325 https://reactome.org/PathwayBrowser/#/R-CEL-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6809720 https://reactome.org/PathwayBrowser/#/R-CEL-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6809777 https://reactome.org/PathwayBrowser/#/R-CEL-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6809778 https://reactome.org/PathwayBrowser/#/R-CEL-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-6810410 https://reactome.org/PathwayBrowser/#/R-CEL-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6810464 https://reactome.org/PathwayBrowser/#/R-CEL-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6811504 https://reactome.org/PathwayBrowser/#/R-CEL-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6813720 https://reactome.org/PathwayBrowser/#/R-CEL-6813720 NCEH1 hydrolyzes cholesterol esters IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6813740 https://reactome.org/PathwayBrowser/#/R-CEL-6813740 GDE1 hydrolyzes GroPIns IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-6814254 https://reactome.org/PathwayBrowser/#/R-CEL-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-6814797 https://reactome.org/PathwayBrowser/#/R-CEL-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-69199 https://reactome.org/PathwayBrowser/#/R-CEL-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70262 https://reactome.org/PathwayBrowser/#/R-CEL-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70479 https://reactome.org/PathwayBrowser/#/R-CEL-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70494 https://reactome.org/PathwayBrowser/#/R-CEL-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70569 https://reactome.org/PathwayBrowser/#/R-CEL-70569 arginine + H2O => ornithine + urea [ARG1] IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70609 https://reactome.org/PathwayBrowser/#/R-CEL-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70785 https://reactome.org/PathwayBrowser/#/R-CEL-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70870 https://reactome.org/PathwayBrowser/#/R-CEL-70870 ECHS1 hydrates methacrylyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70903 https://reactome.org/PathwayBrowser/#/R-CEL-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-70906 https://reactome.org/PathwayBrowser/#/R-CEL-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-70982 https://reactome.org/PathwayBrowser/#/R-CEL-70982 FH tetramer hydrates fumarate to L-malate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71146 https://reactome.org/PathwayBrowser/#/R-CEL-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71296 https://reactome.org/PathwayBrowser/#/R-CEL-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71660 https://reactome.org/PathwayBrowser/#/R-CEL-71660 Enolase dimers dehydrates 2PG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-71732 https://reactome.org/PathwayBrowser/#/R-CEL-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73608 https://reactome.org/PathwayBrowser/#/R-CEL-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73797 https://reactome.org/PathwayBrowser/#/R-CEL-73797 FAICAR => IMP + H2O IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-73815 https://reactome.org/PathwayBrowser/#/R-CEL-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-74241 https://reactome.org/PathwayBrowser/#/R-CEL-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-74248 https://reactome.org/PathwayBrowser/#/R-CEL-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-74948 https://reactome.org/PathwayBrowser/#/R-CEL-74948 PP2A dephosphorylates p-RHO to RHO IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-75899 https://reactome.org/PathwayBrowser/#/R-CEL-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Caenorhabditis elegans 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-76590 https://reactome.org/PathwayBrowser/#/R-CEL-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77256 https://reactome.org/PathwayBrowser/#/R-CEL-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77277 https://reactome.org/PathwayBrowser/#/R-CEL-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77301 https://reactome.org/PathwayBrowser/#/R-CEL-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77314 https://reactome.org/PathwayBrowser/#/R-CEL-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77325 https://reactome.org/PathwayBrowser/#/R-CEL-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77333 https://reactome.org/PathwayBrowser/#/R-CEL-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-77344 https://reactome.org/PathwayBrowser/#/R-CEL-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-77615 https://reactome.org/PathwayBrowser/#/R-CEL-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-870437 https://reactome.org/PathwayBrowser/#/R-CEL-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8848339 https://reactome.org/PathwayBrowser/#/R-CEL-8848339 PNPLA5 hydrolyzes TAG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8848484 https://reactome.org/PathwayBrowser/#/R-CEL-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8849969 https://reactome.org/PathwayBrowser/#/R-CEL-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8850594 https://reactome.org/PathwayBrowser/#/R-CEL-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Caenorhabditis elegans 15377 R-ALL-2022884 H2O [Golgi lumen] R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-ALL-2022884 H2O [Golgi lumen] R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-8853686 https://reactome.org/PathwayBrowser/#/R-CEL-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8854173 https://reactome.org/PathwayBrowser/#/R-CEL-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8854255 https://reactome.org/PathwayBrowser/#/R-CEL-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8854329 https://reactome.org/PathwayBrowser/#/R-CEL-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8854612 https://reactome.org/PathwayBrowser/#/R-CEL-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8855490 https://reactome.org/PathwayBrowser/#/R-CEL-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-8856951 https://reactome.org/PathwayBrowser/#/R-CEL-8856951 PP2A demethylation by PPME1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8864125 https://reactome.org/PathwayBrowser/#/R-CEL-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8866405 https://reactome.org/PathwayBrowser/#/R-CEL-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8866542 https://reactome.org/PathwayBrowser/#/R-CEL-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8867047 https://reactome.org/PathwayBrowser/#/R-CEL-8867047 PTPN3 dephosphorylates EPS15 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8867658 https://reactome.org/PathwayBrowser/#/R-CEL-8867658 PTPN3 dephosphorylates MAPK12 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8868648 https://reactome.org/PathwayBrowser/#/R-CEL-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8868658 https://reactome.org/PathwayBrowser/#/R-CEL-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8868661 https://reactome.org/PathwayBrowser/#/R-CEL-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8869206 https://reactome.org/PathwayBrowser/#/R-CEL-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8874435 https://reactome.org/PathwayBrowser/#/R-CEL-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Caenorhabditis elegans 15377 R-ALL-5668574 H2O [melanosome lumen] R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-8878654 https://reactome.org/PathwayBrowser/#/R-CEL-8878654 ACP6 hydrolyses MYS-LPA IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8932633 https://reactome.org/PathwayBrowser/#/R-CEL-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Caenorhabditis elegans 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-893596 https://reactome.org/PathwayBrowser/#/R-CEL-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8937442 https://reactome.org/PathwayBrowser/#/R-CEL-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8943279 https://reactome.org/PathwayBrowser/#/R-CEL-8943279 GGT dimers hydrolyse GSH IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8952137 https://reactome.org/PathwayBrowser/#/R-CEL-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-8952251 https://reactome.org/PathwayBrowser/#/R-CEL-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Caenorhabditis elegans 15377 R-ALL-2022884 H2O [Golgi lumen] R-CEL-8953499 https://reactome.org/PathwayBrowser/#/R-CEL-8953499 IMPAD1 hydrolyses PAP to AMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8955794 https://reactome.org/PathwayBrowser/#/R-CEL-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-8955817 https://reactome.org/PathwayBrowser/#/R-CEL-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8981637 https://reactome.org/PathwayBrowser/#/R-CEL-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-8985594 https://reactome.org/PathwayBrowser/#/R-CEL-8985594 MYO9B inactivates RHOA IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-9008822 https://reactome.org/PathwayBrowser/#/R-CEL-9008822 PPM1D dephosphorylates RUNX2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9013022 https://reactome.org/PathwayBrowser/#/R-CEL-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9013144 https://reactome.org/PathwayBrowser/#/R-CEL-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9013161 https://reactome.org/PathwayBrowser/#/R-CEL-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9013437 https://reactome.org/PathwayBrowser/#/R-CEL-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9014295 https://reactome.org/PathwayBrowser/#/R-CEL-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9014434 https://reactome.org/PathwayBrowser/#/R-CEL-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9014641 https://reactome.org/PathwayBrowser/#/R-CEL-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9017488 https://reactome.org/PathwayBrowser/#/R-CEL-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018745 https://reactome.org/PathwayBrowser/#/R-CEL-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018806 https://reactome.org/PathwayBrowser/#/R-CEL-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018814 https://reactome.org/PathwayBrowser/#/R-CEL-9018814 RHOT1 hydrolyzes GTP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018826 https://reactome.org/PathwayBrowser/#/R-CEL-9018826 RHOT2 hydrolyzes GTP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018862 https://reactome.org/PathwayBrowser/#/R-CEL-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018868 https://reactome.org/PathwayBrowser/#/R-CEL-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018877 https://reactome.org/PathwayBrowser/#/R-CEL-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9018895 https://reactome.org/PathwayBrowser/#/R-CEL-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020252 https://reactome.org/PathwayBrowser/#/R-CEL-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020253 https://reactome.org/PathwayBrowser/#/R-CEL-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020257 https://reactome.org/PathwayBrowser/#/R-CEL-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020258 https://reactome.org/PathwayBrowser/#/R-CEL-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020270 https://reactome.org/PathwayBrowser/#/R-CEL-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020271 https://reactome.org/PathwayBrowser/#/R-CEL-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9020273 https://reactome.org/PathwayBrowser/#/R-CEL-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9024890 https://reactome.org/PathwayBrowser/#/R-CEL-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9033491 https://reactome.org/PathwayBrowser/#/R-CEL-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-936883 https://reactome.org/PathwayBrowser/#/R-CEL-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-936895 https://reactome.org/PathwayBrowser/#/R-CEL-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-939763 https://reactome.org/PathwayBrowser/#/R-CEL-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-947531 https://reactome.org/PathwayBrowser/#/R-CEL-947531 Molybdenum ion transfer onto molybdopterin IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-947535 https://reactome.org/PathwayBrowser/#/R-CEL-947535 Cyclisation of GTP to precursor Z IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-947591 https://reactome.org/PathwayBrowser/#/R-CEL-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9624893 https://reactome.org/PathwayBrowser/#/R-CEL-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9629675 https://reactome.org/PathwayBrowser/#/R-CEL-9629675 PDE3A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9638075 https://reactome.org/PathwayBrowser/#/R-CEL-9638075 HEXB cleaves the terminal GalNAc from DS IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9638076 https://reactome.org/PathwayBrowser/#/R-CEL-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9638078 https://reactome.org/PathwayBrowser/#/R-CEL-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9644869 https://reactome.org/PathwayBrowser/#/R-CEL-9644869 p-S54-PDE4B hydrolyses cAMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9647994 https://reactome.org/PathwayBrowser/#/R-CEL-9647994 RAS proteins are depalmitoylated IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9653514 https://reactome.org/PathwayBrowser/#/R-CEL-9653514 USP17L2 deubiquitinates RCE1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9656891 https://reactome.org/PathwayBrowser/#/R-CEL-9656891 OPN1SW binds 11cRAL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9656893 https://reactome.org/PathwayBrowser/#/R-CEL-9656893 OPN1MW binds 11cRAL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9658445 https://reactome.org/PathwayBrowser/#/R-CEL-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9661417 https://reactome.org/PathwayBrowser/#/R-CEL-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9693282 https://reactome.org/PathwayBrowser/#/R-CEL-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-9701565 https://reactome.org/PathwayBrowser/#/R-CEL-9701565 HDACs deacetylate p-STAT3 dimers IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9705507 https://reactome.org/PathwayBrowser/#/R-CEL-9705507 PDE3B hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9706399 https://reactome.org/PathwayBrowser/#/R-CEL-9706399 RHOBTB3 hydrolyzes ATP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9708261 https://reactome.org/PathwayBrowser/#/R-CEL-9708261 PDE4A hydrolyses cAMP to AMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9727567 https://reactome.org/PathwayBrowser/#/R-CEL-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9750546 https://reactome.org/PathwayBrowser/#/R-CEL-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9750617 https://reactome.org/PathwayBrowser/#/R-CEL-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9750656 https://reactome.org/PathwayBrowser/#/R-CEL-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753278 https://reactome.org/PathwayBrowser/#/R-CEL-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753280 https://reactome.org/PathwayBrowser/#/R-CEL-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753283 https://reactome.org/PathwayBrowser/#/R-CEL-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753284 https://reactome.org/PathwayBrowser/#/R-CEL-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753632 https://reactome.org/PathwayBrowser/#/R-CEL-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753634 https://reactome.org/PathwayBrowser/#/R-CEL-9753634 GGT dimers hydrolyse APAP-SG IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9753944 https://reactome.org/PathwayBrowser/#/R-CEL-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9754964 https://reactome.org/PathwayBrowser/#/R-CEL-9754964 ADA deamidates RBV IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9755030 https://reactome.org/PathwayBrowser/#/R-CEL-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9755078 https://reactome.org/PathwayBrowser/#/R-CEL-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CEL-975594 https://reactome.org/PathwayBrowser/#/R-CEL-975594 PLB1 hydrolyses RPALM to atROL IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-977324 https://reactome.org/PathwayBrowser/#/R-CEL-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9794120 https://reactome.org/PathwayBrowser/#/R-CEL-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9794572 https://reactome.org/PathwayBrowser/#/R-CEL-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Caenorhabditis elegans 15377 R-ALL-113518 H2O [nucleoplasm] R-CEL-9825772 https://reactome.org/PathwayBrowser/#/R-CEL-9825772 SIRT1 deacetylates HINT1 dimer IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-983144 https://reactome.org/PathwayBrowser/#/R-CEL-983144 Transport of Antigen peptide in to ER IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9837419 https://reactome.org/PathwayBrowser/#/R-CEL-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9838004 https://reactome.org/PathwayBrowser/#/R-CEL-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9838081 https://reactome.org/PathwayBrowser/#/R-CEL-9838081 LONP1 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9838289 https://reactome.org/PathwayBrowser/#/R-CEL-9838289 CLPXP degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9839059 https://reactome.org/PathwayBrowser/#/R-CEL-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9839105 https://reactome.org/PathwayBrowser/#/R-CEL-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9839113 https://reactome.org/PathwayBrowser/#/R-CEL-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9840795 https://reactome.org/PathwayBrowser/#/R-CEL-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9840833 https://reactome.org/PathwayBrowser/#/R-CEL-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9840884 https://reactome.org/PathwayBrowser/#/R-CEL-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Caenorhabditis elegans 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CEL-9841189 https://reactome.org/PathwayBrowser/#/R-CEL-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9853385 https://reactome.org/PathwayBrowser/#/R-CEL-9853385 PPP1CC dephosphorylates PLK1 IEA Caenorhabditis elegans 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CEL-9861626 https://reactome.org/PathwayBrowser/#/R-CEL-9861626 SIRT4 cleaves lipoyl from DLAT IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9861725 https://reactome.org/PathwayBrowser/#/R-CEL-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9865226 https://reactome.org/PathwayBrowser/#/R-CEL-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9912636 https://reactome.org/PathwayBrowser/#/R-CEL-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9912655 https://reactome.org/PathwayBrowser/#/R-CEL-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9912747 https://reactome.org/PathwayBrowser/#/R-CEL-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9912751 https://reactome.org/PathwayBrowser/#/R-CEL-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9915971 https://reactome.org/PathwayBrowser/#/R-CEL-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Caenorhabditis elegans 15377 R-ALL-29356 H2O [cytosol] R-CEL-9915997 https://reactome.org/PathwayBrowser/#/R-CEL-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Caenorhabditis elegans 15377 R-ALL-109276 H2O [extracellular region] R-CFA-109278 https://reactome.org/PathwayBrowser/#/R-CFA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-109291 https://reactome.org/PathwayBrowser/#/R-CFA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109380 https://reactome.org/PathwayBrowser/#/R-CFA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109387 https://reactome.org/PathwayBrowser/#/R-CFA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109415 https://reactome.org/PathwayBrowser/#/R-CFA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109449 https://reactome.org/PathwayBrowser/#/R-CFA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109470 https://reactome.org/PathwayBrowser/#/R-CFA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-109480 https://reactome.org/PathwayBrowser/#/R-CFA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-109514 https://reactome.org/PathwayBrowser/#/R-CFA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111742 https://reactome.org/PathwayBrowser/#/R-CFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111751 https://reactome.org/PathwayBrowser/#/R-CFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111804 https://reactome.org/PathwayBrowser/#/R-CFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111879 https://reactome.org/PathwayBrowser/#/R-CFA-111879 PIP2 hydrolysis IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111955 https://reactome.org/PathwayBrowser/#/R-CFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-111962 https://reactome.org/PathwayBrowser/#/R-CFA-111962 PDE4A,C,D hydrolyse cAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-112037 https://reactome.org/PathwayBrowser/#/R-CFA-112037 Inactivation of PLC beta IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-113503 https://reactome.org/PathwayBrowser/#/R-CFA-113503 PP2A mediated localization of RB1 protein in chromatin IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1169192 https://reactome.org/PathwayBrowser/#/R-CFA-1169192 PTP1B dephosphorylates GHR IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1183128 https://reactome.org/PathwayBrowser/#/R-CFA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1237129 https://reactome.org/PathwayBrowser/#/R-CFA-1237129 Acireductone is created IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1247910 https://reactome.org/PathwayBrowser/#/R-CFA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1247935 https://reactome.org/PathwayBrowser/#/R-CFA-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-1363274 https://reactome.org/PathwayBrowser/#/R-CFA-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-1363276 https://reactome.org/PathwayBrowser/#/R-CFA-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1369065 https://reactome.org/PathwayBrowser/#/R-CFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-139906 https://reactome.org/PathwayBrowser/#/R-CFA-139906 Activation of BAD by calcineurin IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-140359 https://reactome.org/PathwayBrowser/#/R-CFA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1454916 https://reactome.org/PathwayBrowser/#/R-CFA-1454916 The ABCC family mediates organic anion transport IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1454928 https://reactome.org/PathwayBrowser/#/R-CFA-1454928 ABCG4 may mediate cholesterol efflux IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1467457 https://reactome.org/PathwayBrowser/#/R-CFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1467466 https://reactome.org/PathwayBrowser/#/R-CFA-1467466 ABCA4 mediates atRAL transport IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1474146 https://reactome.org/PathwayBrowser/#/R-CFA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482543 https://reactome.org/PathwayBrowser/#/R-CFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482604 https://reactome.org/PathwayBrowser/#/R-CFA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482612 https://reactome.org/PathwayBrowser/#/R-CFA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482656 https://reactome.org/PathwayBrowser/#/R-CFA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482685 https://reactome.org/PathwayBrowser/#/R-CFA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1482745 https://reactome.org/PathwayBrowser/#/R-CFA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1482759 https://reactome.org/PathwayBrowser/#/R-CFA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482771 https://reactome.org/PathwayBrowser/#/R-CFA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482777 https://reactome.org/PathwayBrowser/#/R-CFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482811 https://reactome.org/PathwayBrowser/#/R-CFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482816 https://reactome.org/PathwayBrowser/#/R-CFA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482825 https://reactome.org/PathwayBrowser/#/R-CFA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482828 https://reactome.org/PathwayBrowser/#/R-CFA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1482847 https://reactome.org/PathwayBrowser/#/R-CFA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482856 https://reactome.org/PathwayBrowser/#/R-CFA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482862 https://reactome.org/PathwayBrowser/#/R-CFA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482884 https://reactome.org/PathwayBrowser/#/R-CFA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482887 https://reactome.org/PathwayBrowser/#/R-CFA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482897 https://reactome.org/PathwayBrowser/#/R-CFA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482900 https://reactome.org/PathwayBrowser/#/R-CFA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482920 https://reactome.org/PathwayBrowser/#/R-CFA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1482932 https://reactome.org/PathwayBrowser/#/R-CFA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1483096 https://reactome.org/PathwayBrowser/#/R-CFA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1483159 https://reactome.org/PathwayBrowser/#/R-CFA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1483182 https://reactome.org/PathwayBrowser/#/R-CFA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1483203 https://reactome.org/PathwayBrowser/#/R-CFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-159425 https://reactome.org/PathwayBrowser/#/R-CFA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602368 https://reactome.org/PathwayBrowser/#/R-CFA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602374 https://reactome.org/PathwayBrowser/#/R-CFA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602377 https://reactome.org/PathwayBrowser/#/R-CFA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602398 https://reactome.org/PathwayBrowser/#/R-CFA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602399 https://reactome.org/PathwayBrowser/#/R-CFA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602417 https://reactome.org/PathwayBrowser/#/R-CFA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-1602446 https://reactome.org/PathwayBrowser/#/R-CFA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605591 https://reactome.org/PathwayBrowser/#/R-CFA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605595 https://reactome.org/PathwayBrowser/#/R-CFA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605624 https://reactome.org/PathwayBrowser/#/R-CFA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605632 https://reactome.org/PathwayBrowser/#/R-CFA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1605723 https://reactome.org/PathwayBrowser/#/R-CFA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605724 https://reactome.org/PathwayBrowser/#/R-CFA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605736 https://reactome.org/PathwayBrowser/#/R-CFA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1605768 https://reactome.org/PathwayBrowser/#/R-CFA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1606312 https://reactome.org/PathwayBrowser/#/R-CFA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1606564 https://reactome.org/PathwayBrowser/#/R-CFA-1606564 GALC hydrolyzes GalCer IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1606583 https://reactome.org/PathwayBrowser/#/R-CFA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1606602 https://reactome.org/PathwayBrowser/#/R-CFA-1606602 ASAH1 hydrolyzes ceramide IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1606789 https://reactome.org/PathwayBrowser/#/R-CFA-1606789 ARSB hydrolyses DS IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-1606839 https://reactome.org/PathwayBrowser/#/R-CFA-1606839 ARSC hydrolyzes steroid sulfates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1614524 https://reactome.org/PathwayBrowser/#/R-CFA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1614583 https://reactome.org/PathwayBrowser/#/R-CFA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to pyruvate and H2S IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-162425 https://reactome.org/PathwayBrowser/#/R-CFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-162729 https://reactome.org/PathwayBrowser/#/R-CFA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-162857 https://reactome.org/PathwayBrowser/#/R-CFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1630304 https://reactome.org/PathwayBrowser/#/R-CFA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1630306 https://reactome.org/PathwayBrowser/#/R-CFA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1638032 https://reactome.org/PathwayBrowser/#/R-CFA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1638053 https://reactome.org/PathwayBrowser/#/R-CFA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1638821 https://reactome.org/PathwayBrowser/#/R-CFA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-164832 https://reactome.org/PathwayBrowser/#/R-CFA-164832 ATPase synthesizes ATP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1667005 https://reactome.org/PathwayBrowser/#/R-CFA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675795 https://reactome.org/PathwayBrowser/#/R-CFA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675824 https://reactome.org/PathwayBrowser/#/R-CFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675836 https://reactome.org/PathwayBrowser/#/R-CFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675949 https://reactome.org/PathwayBrowser/#/R-CFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675988 https://reactome.org/PathwayBrowser/#/R-CFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1675994 https://reactome.org/PathwayBrowser/#/R-CFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676005 https://reactome.org/PathwayBrowser/#/R-CFA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676020 https://reactome.org/PathwayBrowser/#/R-CFA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676065 https://reactome.org/PathwayBrowser/#/R-CFA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676105 https://reactome.org/PathwayBrowser/#/R-CFA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676114 https://reactome.org/PathwayBrowser/#/R-CFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676124 https://reactome.org/PathwayBrowser/#/R-CFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676141 https://reactome.org/PathwayBrowser/#/R-CFA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676149 https://reactome.org/PathwayBrowser/#/R-CFA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676162 https://reactome.org/PathwayBrowser/#/R-CFA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676164 https://reactome.org/PathwayBrowser/#/R-CFA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676174 https://reactome.org/PathwayBrowser/#/R-CFA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676177 https://reactome.org/PathwayBrowser/#/R-CFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676203 https://reactome.org/PathwayBrowser/#/R-CFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1676204 https://reactome.org/PathwayBrowser/#/R-CFA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1678650 https://reactome.org/PathwayBrowser/#/R-CFA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1678708 https://reactome.org/PathwayBrowser/#/R-CFA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1678716 https://reactome.org/PathwayBrowser/#/R-CFA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1678742 https://reactome.org/PathwayBrowser/#/R-CFA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1678854 https://reactome.org/PathwayBrowser/#/R-CFA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-170153 https://reactome.org/PathwayBrowser/#/R-CFA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-170158 https://reactome.org/PathwayBrowser/#/R-CFA-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-170161 https://reactome.org/PathwayBrowser/#/R-CFA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-173739 https://reactome.org/PathwayBrowser/#/R-CFA-173739 Spontaneous hydrolysis of C3 thioester IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-174110 https://reactome.org/PathwayBrowser/#/R-CFA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-174124 https://reactome.org/PathwayBrowser/#/R-CFA-174124 Dephosphorylation of phospho-Cdh1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-174391 https://reactome.org/PathwayBrowser/#/R-CFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-174401 https://reactome.org/PathwayBrowser/#/R-CFA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-174439 https://reactome.org/PathwayBrowser/#/R-CFA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-176606 https://reactome.org/PathwayBrowser/#/R-CFA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-177923 https://reactome.org/PathwayBrowser/#/R-CFA-177923 Sustained activation of SRC kinase by SHP2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-177924 https://reactome.org/PathwayBrowser/#/R-CFA-177924 Dephosphorylation of Gab1 by SHP2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-177926 https://reactome.org/PathwayBrowser/#/R-CFA-177926 Dephosphorylation of PAG by SHP2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-177935 https://reactome.org/PathwayBrowser/#/R-CFA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1793182 https://reactome.org/PathwayBrowser/#/R-CFA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1793186 https://reactome.org/PathwayBrowser/#/R-CFA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1793207 https://reactome.org/PathwayBrowser/#/R-CFA-1793207 ARSB hydrolyses C4S/C6S chains IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-1793209 https://reactome.org/PathwayBrowser/#/R-CFA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855154 https://reactome.org/PathwayBrowser/#/R-CFA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855159 https://reactome.org/PathwayBrowser/#/R-CFA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-1855163 https://reactome.org/PathwayBrowser/#/R-CFA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855165 https://reactome.org/PathwayBrowser/#/R-CFA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855166 https://reactome.org/PathwayBrowser/#/R-CFA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855171 https://reactome.org/PathwayBrowser/#/R-CFA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855174 https://reactome.org/PathwayBrowser/#/R-CFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855177 https://reactome.org/PathwayBrowser/#/R-CFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855180 https://reactome.org/PathwayBrowser/#/R-CFA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855198 https://reactome.org/PathwayBrowser/#/R-CFA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-1855200 https://reactome.org/PathwayBrowser/#/R-CFA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855202 https://reactome.org/PathwayBrowser/#/R-CFA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855205 https://reactome.org/PathwayBrowser/#/R-CFA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855208 https://reactome.org/PathwayBrowser/#/R-CFA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855210 https://reactome.org/PathwayBrowser/#/R-CFA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855211 https://reactome.org/PathwayBrowser/#/R-CFA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855213 https://reactome.org/PathwayBrowser/#/R-CFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855214 https://reactome.org/PathwayBrowser/#/R-CFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855218 https://reactome.org/PathwayBrowser/#/R-CFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855219 https://reactome.org/PathwayBrowser/#/R-CFA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855221 https://reactome.org/PathwayBrowser/#/R-CFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855222 https://reactome.org/PathwayBrowser/#/R-CFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-1855225 https://reactome.org/PathwayBrowser/#/R-CFA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1855232 https://reactome.org/PathwayBrowser/#/R-CFA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1861788 https://reactome.org/PathwayBrowser/#/R-CFA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-1861789 https://reactome.org/PathwayBrowser/#/R-CFA-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-188979 https://reactome.org/PathwayBrowser/#/R-CFA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-189053 https://reactome.org/PathwayBrowser/#/R-CFA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-189062 https://reactome.org/PathwayBrowser/#/R-CFA-189062 lactose + H2O => D-glucose + D-galactose IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-189069 https://reactome.org/PathwayBrowser/#/R-CFA-189069 sucrose + H2O => glucose + fructose IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-189102 https://reactome.org/PathwayBrowser/#/R-CFA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-189406 https://reactome.org/PathwayBrowser/#/R-CFA-189406 4 PBGs bind to form HMB IEA Canis familiaris 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-189488 https://reactome.org/PathwayBrowser/#/R-CFA-189488 UROS transforms HMB to URO3 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-191101 https://reactome.org/PathwayBrowser/#/R-CFA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-191108 https://reactome.org/PathwayBrowser/#/R-CFA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-191114 https://reactome.org/PathwayBrowser/#/R-CFA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-191116 https://reactome.org/PathwayBrowser/#/R-CFA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-192331 https://reactome.org/PathwayBrowser/#/R-CFA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193362 https://reactome.org/PathwayBrowser/#/R-CFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-193385 https://reactome.org/PathwayBrowser/#/R-CFA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-193535 https://reactome.org/PathwayBrowser/#/R-CFA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193711 https://reactome.org/PathwayBrowser/#/R-CFA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193727 https://reactome.org/PathwayBrowser/#/R-CFA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193743 https://reactome.org/PathwayBrowser/#/R-CFA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193766 https://reactome.org/PathwayBrowser/#/R-CFA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-196950 https://reactome.org/PathwayBrowser/#/R-CFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-197186 https://reactome.org/PathwayBrowser/#/R-CFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-199456 https://reactome.org/PathwayBrowser/#/R-CFA-199456 PTEN dephosphorylates PIP3 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-199959 https://reactome.org/PathwayBrowser/#/R-CFA-199959 ERKs are inactivated by protein phosphatase 2A IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-200661 https://reactome.org/PathwayBrowser/#/R-CFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-200740 https://reactome.org/PathwayBrowser/#/R-CFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-201035 https://reactome.org/PathwayBrowser/#/R-CFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-201790 https://reactome.org/PathwayBrowser/#/R-CFA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-202214 https://reactome.org/PathwayBrowser/#/R-CFA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022368 https://reactome.org/PathwayBrowser/#/R-CFA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-202237 https://reactome.org/PathwayBrowser/#/R-CFA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022378 https://reactome.org/PathwayBrowser/#/R-CFA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022379 https://reactome.org/PathwayBrowser/#/R-CFA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022381 https://reactome.org/PathwayBrowser/#/R-CFA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022383 https://reactome.org/PathwayBrowser/#/R-CFA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022396 https://reactome.org/PathwayBrowser/#/R-CFA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022398 https://reactome.org/PathwayBrowser/#/R-CFA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022399 https://reactome.org/PathwayBrowser/#/R-CFA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022403 https://reactome.org/PathwayBrowser/#/R-CFA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022405 https://reactome.org/PathwayBrowser/#/R-CFA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022411 https://reactome.org/PathwayBrowser/#/R-CFA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2022412 https://reactome.org/PathwayBrowser/#/R-CFA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-ALL-2022884 H2O [Golgi lumen] R-CFA-2022887 https://reactome.org/PathwayBrowser/#/R-CFA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2023971 https://reactome.org/PathwayBrowser/#/R-CFA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2023973 https://reactome.org/PathwayBrowser/#/R-CFA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-202407 https://reactome.org/PathwayBrowser/#/R-CFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2028294 https://reactome.org/PathwayBrowser/#/R-CFA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2029468 https://reactome.org/PathwayBrowser/#/R-CFA-2029468 Conversion of PA into DAG by PAP-1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2029471 https://reactome.org/PathwayBrowser/#/R-CFA-2029471 Hydrolysis of PC to PA by PLD IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2029475 https://reactome.org/PathwayBrowser/#/R-CFA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-203797 https://reactome.org/PathwayBrowser/#/R-CFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-204169 https://reactome.org/PathwayBrowser/#/R-CFA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046083 https://reactome.org/PathwayBrowser/#/R-CFA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046088 https://reactome.org/PathwayBrowser/#/R-CFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046090 https://reactome.org/PathwayBrowser/#/R-CFA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046094 https://reactome.org/PathwayBrowser/#/R-CFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046095 https://reactome.org/PathwayBrowser/#/R-CFA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2046100 https://reactome.org/PathwayBrowser/#/R-CFA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2065355 https://reactome.org/PathwayBrowser/#/R-CFA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2065357 https://reactome.org/PathwayBrowser/#/R-CFA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-2066778 https://reactome.org/PathwayBrowser/#/R-CFA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-2066779 https://reactome.org/PathwayBrowser/#/R-CFA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2090037 https://reactome.org/PathwayBrowser/#/R-CFA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2090038 https://reactome.org/PathwayBrowser/#/R-CFA-2090038 NAGLU hydrolyses heparan chain(2) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2090043 https://reactome.org/PathwayBrowser/#/R-CFA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2090079 https://reactome.org/PathwayBrowser/#/R-CFA-2090079 GLB1 hydrolyses linker chain(2) IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-209055 https://reactome.org/PathwayBrowser/#/R-CFA-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15377 R-ALL-351603 H2O [secretory granule lumen] R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2105001 https://reactome.org/PathwayBrowser/#/R-CFA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2130725 https://reactome.org/PathwayBrowser/#/R-CFA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2160874 https://reactome.org/PathwayBrowser/#/R-CFA-2160874 HYAL1 hydrolyses (HA)50 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161195 https://reactome.org/PathwayBrowser/#/R-CFA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161791 https://reactome.org/PathwayBrowser/#/R-CFA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161959 https://reactome.org/PathwayBrowser/#/R-CFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161961 https://reactome.org/PathwayBrowser/#/R-CFA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2161999 https://reactome.org/PathwayBrowser/#/R-CFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-2162187 https://reactome.org/PathwayBrowser/#/R-CFA-2162187 COQ6 hydroxylates DHB IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2162225 https://reactome.org/PathwayBrowser/#/R-CFA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2162226 https://reactome.org/PathwayBrowser/#/R-CFA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-2162227 https://reactome.org/PathwayBrowser/#/R-CFA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-216723 https://reactome.org/PathwayBrowser/#/R-CFA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-216757 https://reactome.org/PathwayBrowser/#/R-CFA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2187401 https://reactome.org/PathwayBrowser/#/R-CFA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-2309773 https://reactome.org/PathwayBrowser/#/R-CFA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2393939 https://reactome.org/PathwayBrowser/#/R-CFA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-2393954 https://reactome.org/PathwayBrowser/#/R-CFA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2408551 https://reactome.org/PathwayBrowser/#/R-CFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2454118 https://reactome.org/PathwayBrowser/#/R-CFA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2465924 https://reactome.org/PathwayBrowser/#/R-CFA-2465924 OPN1LW binds 11cRAL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2466085 https://reactome.org/PathwayBrowser/#/R-CFA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2529015 https://reactome.org/PathwayBrowser/#/R-CFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2584246 https://reactome.org/PathwayBrowser/#/R-CFA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2632521 https://reactome.org/PathwayBrowser/#/R-CFA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-265783 https://reactome.org/PathwayBrowser/#/R-CFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-266012 https://reactome.org/PathwayBrowser/#/R-CFA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-266046 https://reactome.org/PathwayBrowser/#/R-CFA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-266051 https://reactome.org/PathwayBrowser/#/R-CFA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-266070 https://reactome.org/PathwayBrowser/#/R-CFA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-266072 https://reactome.org/PathwayBrowser/#/R-CFA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-266082 https://reactome.org/PathwayBrowser/#/R-CFA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2730847 https://reactome.org/PathwayBrowser/#/R-CFA-2730847 Hydrolysis of PIP2 by PLCG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2730849 https://reactome.org/PathwayBrowser/#/R-CFA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-2855047 https://reactome.org/PathwayBrowser/#/R-CFA-2855047 Hydrolysis of internal thioester in C4b IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-2995330 https://reactome.org/PathwayBrowser/#/R-CFA-2995330 COX10 transforms heme to heme O IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-2995334 https://reactome.org/PathwayBrowser/#/R-CFA-2995334 COX15 transforms heme O to heme A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-2995388 https://reactome.org/PathwayBrowser/#/R-CFA-2995388 PP2A dephosphorylates BANF1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3002811 https://reactome.org/PathwayBrowser/#/R-CFA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3095901 https://reactome.org/PathwayBrowser/#/R-CFA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3215295 https://reactome.org/PathwayBrowser/#/R-CFA-3215295 USP7 deubiquitinates MDM2 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3215310 https://reactome.org/PathwayBrowser/#/R-CFA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3247569 https://reactome.org/PathwayBrowser/#/R-CFA-3247569 PADI4 deiminates Histones IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-3262512 https://reactome.org/PathwayBrowser/#/R-CFA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-3266566 https://reactome.org/PathwayBrowser/#/R-CFA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-3323013 https://reactome.org/PathwayBrowser/#/R-CFA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3341277 https://reactome.org/PathwayBrowser/#/R-CFA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-3341296 https://reactome.org/PathwayBrowser/#/R-CFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3341343 https://reactome.org/PathwayBrowser/#/R-CFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3343700 https://reactome.org/PathwayBrowser/#/R-CFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3371467 https://reactome.org/PathwayBrowser/#/R-CFA-3371467 SIRT1 deacetylates HSF1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-350604 https://reactome.org/PathwayBrowser/#/R-CFA-350604 Agmatine + H2O <=> putrescine + urea IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3640872 https://reactome.org/PathwayBrowser/#/R-CFA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3697882 https://reactome.org/PathwayBrowser/#/R-CFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3769447 https://reactome.org/PathwayBrowser/#/R-CFA-3769447 HDAC1:2-containing complex deacetylate histones IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-377643 https://reactome.org/PathwayBrowser/#/R-CFA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3777129 https://reactome.org/PathwayBrowser/#/R-CFA-3777129 HDAC3 containing complexes deacetylate histone IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3781011 https://reactome.org/PathwayBrowser/#/R-CFA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-3781018 https://reactome.org/PathwayBrowser/#/R-CFA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3782637 https://reactome.org/PathwayBrowser/#/R-CFA-3782637 HDAC8 deacetylates histones IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-3782655 https://reactome.org/PathwayBrowser/#/R-CFA-3782655 HDAC10 deacetylates histone IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-380949 https://reactome.org/PathwayBrowser/#/R-CFA-380949 AMPK is dephosphorylated IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-382553 https://reactome.org/PathwayBrowser/#/R-CFA-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-382560 https://reactome.org/PathwayBrowser/#/R-CFA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-382575 https://reactome.org/PathwayBrowser/#/R-CFA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-383190 https://reactome.org/PathwayBrowser/#/R-CFA-383190 HCO3- transport through ion channel IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-389986 https://reactome.org/PathwayBrowser/#/R-CFA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-390252 https://reactome.org/PathwayBrowser/#/R-CFA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-390393 https://reactome.org/PathwayBrowser/#/R-CFA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-399998 https://reactome.org/PathwayBrowser/#/R-CFA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4084976 https://reactome.org/PathwayBrowser/#/R-CFA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4084989 https://reactome.org/PathwayBrowser/#/R-CFA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4084994 https://reactome.org/PathwayBrowser/#/R-CFA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-4084999 https://reactome.org/PathwayBrowser/#/R-CFA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4085021 https://reactome.org/PathwayBrowser/#/R-CFA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4085029 https://reactome.org/PathwayBrowser/#/R-CFA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4086392 https://reactome.org/PathwayBrowser/#/R-CFA-4086392 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-4088141 https://reactome.org/PathwayBrowser/#/R-CFA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4093339 https://reactome.org/PathwayBrowser/#/R-CFA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-416559 https://reactome.org/PathwayBrowser/#/R-CFA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-418553 https://reactome.org/PathwayBrowser/#/R-CFA-418553 cAMP degradation by Phosphodiesterases IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428205 https://reactome.org/PathwayBrowser/#/R-CFA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428231 https://reactome.org/PathwayBrowser/#/R-CFA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428262 https://reactome.org/PathwayBrowser/#/R-CFA-428262 ACER3 hydrolyzes phytoceramide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428664 https://reactome.org/PathwayBrowser/#/R-CFA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-428690 https://reactome.org/PathwayBrowser/#/R-CFA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-428696 https://reactome.org/PathwayBrowser/#/R-CFA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-429860 https://reactome.org/PathwayBrowser/#/R-CFA-429860 DCP1-DCP2 complex decaps mRNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-429955 https://reactome.org/PathwayBrowser/#/R-CFA-429955 CCR4-NOT complex deadenylates mRNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-429961 https://reactome.org/PathwayBrowser/#/R-CFA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-429992 https://reactome.org/PathwayBrowser/#/R-CFA-429992 PARN deadenylates mRNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-430021 https://reactome.org/PathwayBrowser/#/R-CFA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-430028 https://reactome.org/PathwayBrowser/#/R-CFA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-432010 https://reactome.org/PathwayBrowser/#/R-CFA-432010 Aquaporin-1 passively transports water into cell IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-432010 https://reactome.org/PathwayBrowser/#/R-CFA-432010 Aquaporin-1 passively transports water into cell IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-432054 https://reactome.org/PathwayBrowser/#/R-CFA-432054 Aquaporin-1 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-432054 https://reactome.org/PathwayBrowser/#/R-CFA-432054 Aquaporin-1 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-432065 https://reactome.org/PathwayBrowser/#/R-CFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-432065 https://reactome.org/PathwayBrowser/#/R-CFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-432067 https://reactome.org/PathwayBrowser/#/R-CFA-432067 Aquaporin-4 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-432067 https://reactome.org/PathwayBrowser/#/R-CFA-432067 Aquaporin-4 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-4419948 https://reactome.org/PathwayBrowser/#/R-CFA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-445714 https://reactome.org/PathwayBrowser/#/R-CFA-445714 Aquaporin-3 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-445714 https://reactome.org/PathwayBrowser/#/R-CFA-445714 Aquaporin-3 passively transports water out of cell IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-449937 https://reactome.org/PathwayBrowser/#/R-CFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-452036 https://reactome.org/PathwayBrowser/#/R-CFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-4551451 https://reactome.org/PathwayBrowser/#/R-CFA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-507868 https://reactome.org/PathwayBrowser/#/R-CFA-507868 Aquaporins passively transport water into cells IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-507868 https://reactome.org/PathwayBrowser/#/R-CFA-507868 Aquaporins passively transport water into cells IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-507870 https://reactome.org/PathwayBrowser/#/R-CFA-507870 Aquaporins passively transport water out of cells IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-507870 https://reactome.org/PathwayBrowser/#/R-CFA-507870 Aquaporins passively transport water out of cells IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5221130 https://reactome.org/PathwayBrowser/#/R-CFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5223313 https://reactome.org/PathwayBrowser/#/R-CFA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5223317 https://reactome.org/PathwayBrowser/#/R-CFA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5251955 https://reactome.org/PathwayBrowser/#/R-CFA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5251959 https://reactome.org/PathwayBrowser/#/R-CFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5251989 https://reactome.org/PathwayBrowser/#/R-CFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5362459 https://reactome.org/PathwayBrowser/#/R-CFA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-5433072 https://reactome.org/PathwayBrowser/#/R-CFA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5433074 https://reactome.org/PathwayBrowser/#/R-CFA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-548843 https://reactome.org/PathwayBrowser/#/R-CFA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5603114 https://reactome.org/PathwayBrowser/#/R-CFA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5607735 https://reactome.org/PathwayBrowser/#/R-CFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5623513 https://reactome.org/PathwayBrowser/#/R-CFA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5628905 https://reactome.org/PathwayBrowser/#/R-CFA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5631885 https://reactome.org/PathwayBrowser/#/R-CFA-5631885 PRDX1 overoxidizes IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5649705 https://reactome.org/PathwayBrowser/#/R-CFA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5653770 https://reactome.org/PathwayBrowser/#/R-CFA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5653786 https://reactome.org/PathwayBrowser/#/R-CFA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-5659861 https://reactome.org/PathwayBrowser/#/R-CFA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Canis familiaris 15377 R-ALL-5668574 H2O [melanosome lumen] R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5665809 https://reactome.org/PathwayBrowser/#/R-CFA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5675373 https://reactome.org/PathwayBrowser/#/R-CFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5675376 https://reactome.org/PathwayBrowser/#/R-CFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5675431 https://reactome.org/PathwayBrowser/#/R-CFA-5675431 PP2A dephosphorylates RAF1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5675433 https://reactome.org/PathwayBrowser/#/R-CFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5676637 https://reactome.org/PathwayBrowser/#/R-CFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5678706 https://reactome.org/PathwayBrowser/#/R-CFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5678863 https://reactome.org/PathwayBrowser/#/R-CFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5679041 https://reactome.org/PathwayBrowser/#/R-CFA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5682285 https://reactome.org/PathwayBrowser/#/R-CFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5683405 https://reactome.org/PathwayBrowser/#/R-CFA-5683405 PPP5C dephosphorylates TP53BP1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5683714 https://reactome.org/PathwayBrowser/#/R-CFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5683967 https://reactome.org/PathwayBrowser/#/R-CFA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Canis familiaris 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-CFA-5684864 https://reactome.org/PathwayBrowser/#/R-CFA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Canis familiaris 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-CFA-5685902 https://reactome.org/PathwayBrowser/#/R-CFA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5685994 https://reactome.org/PathwayBrowser/#/R-CFA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5687464 https://reactome.org/PathwayBrowser/#/R-CFA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5687664 https://reactome.org/PathwayBrowser/#/R-CFA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5687758 https://reactome.org/PathwayBrowser/#/R-CFA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5688797 https://reactome.org/PathwayBrowser/#/R-CFA-5688797 ATXN3 family cleave Ub chains IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5688837 https://reactome.org/PathwayBrowser/#/R-CFA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5689000 https://reactome.org/PathwayBrowser/#/R-CFA-5689000 AADAC deacetylates PHEN IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5689950 https://reactome.org/PathwayBrowser/#/R-CFA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5689972 https://reactome.org/PathwayBrowser/#/R-CFA-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5689973 https://reactome.org/PathwayBrowser/#/R-CFA-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690043 https://reactome.org/PathwayBrowser/#/R-CFA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5690066 https://reactome.org/PathwayBrowser/#/R-CFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5690080 https://reactome.org/PathwayBrowser/#/R-CFA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690152 https://reactome.org/PathwayBrowser/#/R-CFA-5690152 USP5 cleaves polyubiquitin IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5690157 https://reactome.org/PathwayBrowser/#/R-CFA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690159 https://reactome.org/PathwayBrowser/#/R-CFA-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690196 https://reactome.org/PathwayBrowser/#/R-CFA-5690196 USP8 deubiquitinates RNF128 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690319 https://reactome.org/PathwayBrowser/#/R-CFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-5690517 https://reactome.org/PathwayBrowser/#/R-CFA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5690759 https://reactome.org/PathwayBrowser/#/R-CFA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5690790 https://reactome.org/PathwayBrowser/#/R-CFA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690808 https://reactome.org/PathwayBrowser/#/R-CFA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690856 https://reactome.org/PathwayBrowser/#/R-CFA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5690870 https://reactome.org/PathwayBrowser/#/R-CFA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5691381 https://reactome.org/PathwayBrowser/#/R-CFA-5691381 MYSM1 deubiquitinates Histone H2A IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5691411 https://reactome.org/PathwayBrowser/#/R-CFA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5691439 https://reactome.org/PathwayBrowser/#/R-CFA-5691439 BRISC complex deubiquitinates NLRP3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5691507 https://reactome.org/PathwayBrowser/#/R-CFA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5691512 https://reactome.org/PathwayBrowser/#/R-CFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5692462 https://reactome.org/PathwayBrowser/#/R-CFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5692480 https://reactome.org/PathwayBrowser/#/R-CFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5692754 https://reactome.org/PathwayBrowser/#/R-CFA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5693153 https://reactome.org/PathwayBrowser/#/R-CFA-5693153 PPM1K dephosphorylates p-BCKDH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5693373 https://reactome.org/PathwayBrowser/#/R-CFA-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5693608 https://reactome.org/PathwayBrowser/#/R-CFA-5693608 Initial resection of double-strand break ends IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-5693724 https://reactome.org/PathwayBrowser/#/R-CFA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5693742 https://reactome.org/PathwayBrowser/#/R-CFA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5693783 https://reactome.org/PathwayBrowser/#/R-CFA-5693783 NAALADases hydrolyse NAAG IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-5693807 https://reactome.org/PathwayBrowser/#/R-CFA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694077 https://reactome.org/PathwayBrowser/#/R-CFA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-5694109 https://reactome.org/PathwayBrowser/#/R-CFA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694126 https://reactome.org/PathwayBrowser/#/R-CFA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5694137 https://reactome.org/PathwayBrowser/#/R-CFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694421 https://reactome.org/PathwayBrowser/#/R-CFA-5694421 PP6 dephosphorylates SEC24 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694485 https://reactome.org/PathwayBrowser/#/R-CFA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5694563 https://reactome.org/PathwayBrowser/#/R-CFA-5694563 ABHD10 hydrolyses MPAG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5694583 https://reactome.org/PathwayBrowser/#/R-CFA-5694583 ABHD4 hydrolyses NAPE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5695964 https://reactome.org/PathwayBrowser/#/R-CFA-5695964 ABHD14B hydrolyses PNPB IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696049 https://reactome.org/PathwayBrowser/#/R-CFA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5696197 https://reactome.org/PathwayBrowser/#/R-CFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696230 https://reactome.org/PathwayBrowser/#/R-CFA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696365 https://reactome.org/PathwayBrowser/#/R-CFA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5696408 https://reactome.org/PathwayBrowser/#/R-CFA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-5696415 https://reactome.org/PathwayBrowser/#/R-CFA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696534 https://reactome.org/PathwayBrowser/#/R-CFA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696600 https://reactome.org/PathwayBrowser/#/R-CFA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5696605 https://reactome.org/PathwayBrowser/#/R-CFA-5696605 USP12, USP26 deubiquitinate AR IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696627 https://reactome.org/PathwayBrowser/#/R-CFA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696872 https://reactome.org/PathwayBrowser/#/R-CFA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5696914 https://reactome.org/PathwayBrowser/#/R-CFA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696945 https://reactome.org/PathwayBrowser/#/R-CFA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5696947 https://reactome.org/PathwayBrowser/#/R-CFA-5696947 USP47 deubiquitinates POLB IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5696958 https://reactome.org/PathwayBrowser/#/R-CFA-5696958 USP44 deubiquitinates CDC20 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5696960 https://reactome.org/PathwayBrowser/#/R-CFA-5696960 USP49 deubiquitinates H2B IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-5696968 https://reactome.org/PathwayBrowser/#/R-CFA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-5697009 https://reactome.org/PathwayBrowser/#/R-CFA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6781764 https://reactome.org/PathwayBrowser/#/R-CFA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6781779 https://reactome.org/PathwayBrowser/#/R-CFA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6781814 https://reactome.org/PathwayBrowser/#/R-CFA-6781814 USP19 deubiquitinates RNF123 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6781897 https://reactome.org/PathwayBrowser/#/R-CFA-6781897 USP11 deubiquitinates NFKBIA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6782069 https://reactome.org/PathwayBrowser/#/R-CFA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6782106 https://reactome.org/PathwayBrowser/#/R-CFA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6782628 https://reactome.org/PathwayBrowser/#/R-CFA-6782628 USP8 deubiquitinates STAM2:HGS IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6782820 https://reactome.org/PathwayBrowser/#/R-CFA-6782820 USP17 deubiquitinates SUDS3 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6783177 https://reactome.org/PathwayBrowser/#/R-CFA-6783177 USP21 deubiquitinates GATA3,IL33 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6784402 https://reactome.org/PathwayBrowser/#/R-CFA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6784959 https://reactome.org/PathwayBrowser/#/R-CFA-6784959 BPHL hydrolyses VACV to ACV IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6786190 https://reactome.org/PathwayBrowser/#/R-CFA-6786190 CMBL hydrolyses OM to OLMS IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6786421 https://reactome.org/PathwayBrowser/#/R-CFA-6786421 CHIA hydrolyses chitin IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6786650 https://reactome.org/PathwayBrowser/#/R-CFA-6786650 DDHD1,2 hydrolyse PA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6787632 https://reactome.org/PathwayBrowser/#/R-CFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6788295 https://reactome.org/PathwayBrowser/#/R-CFA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6788912 https://reactome.org/PathwayBrowser/#/R-CFA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Canis familiaris 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6789310 https://reactome.org/PathwayBrowser/#/R-CFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6792445 https://reactome.org/PathwayBrowser/#/R-CFA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6792863 https://reactome.org/PathwayBrowser/#/R-CFA-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6797627 https://reactome.org/PathwayBrowser/#/R-CFA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6797630 https://reactome.org/PathwayBrowser/#/R-CFA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6797653 https://reactome.org/PathwayBrowser/#/R-CFA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6797913 https://reactome.org/PathwayBrowser/#/R-CFA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6797955 https://reactome.org/PathwayBrowser/#/R-CFA-6797955 ALDH7A1 oxidises BETALD to BET IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6799545 https://reactome.org/PathwayBrowser/#/R-CFA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6799604 https://reactome.org/PathwayBrowser/#/R-CFA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6799695 https://reactome.org/PathwayBrowser/#/R-CFA-6799695 GPX5,6 reduce H2O2 to H2O IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6799977 https://reactome.org/PathwayBrowser/#/R-CFA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6800198 https://reactome.org/PathwayBrowser/#/R-CFA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6800200 https://reactome.org/PathwayBrowser/#/R-CFA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6800299 https://reactome.org/PathwayBrowser/#/R-CFA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6801462 https://reactome.org/PathwayBrowser/#/R-CFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6803545 https://reactome.org/PathwayBrowser/#/R-CFA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6803789 https://reactome.org/PathwayBrowser/#/R-CFA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6805650 https://reactome.org/PathwayBrowser/#/R-CFA-6805650 MTA2-NuRD complex deacetylates TP53 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6807008 https://reactome.org/PathwayBrowser/#/R-CFA-6807008 PTPRJ dephosphorylates MET IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6807027 https://reactome.org/PathwayBrowser/#/R-CFA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6807118 https://reactome.org/PathwayBrowser/#/R-CFA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6807206 https://reactome.org/PathwayBrowser/#/R-CFA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-6809263 https://reactome.org/PathwayBrowser/#/R-CFA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6809320 https://reactome.org/PathwayBrowser/#/R-CFA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6809325 https://reactome.org/PathwayBrowser/#/R-CFA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6809720 https://reactome.org/PathwayBrowser/#/R-CFA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6809777 https://reactome.org/PathwayBrowser/#/R-CFA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6809778 https://reactome.org/PathwayBrowser/#/R-CFA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-6810410 https://reactome.org/PathwayBrowser/#/R-CFA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-6810472 https://reactome.org/PathwayBrowser/#/R-CFA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6813720 https://reactome.org/PathwayBrowser/#/R-CFA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6813740 https://reactome.org/PathwayBrowser/#/R-CFA-6813740 GDE1 hydrolyzes GroPIns IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-6814254 https://reactome.org/PathwayBrowser/#/R-CFA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-6814797 https://reactome.org/PathwayBrowser/#/R-CFA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-69199 https://reactome.org/PathwayBrowser/#/R-CFA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70262 https://reactome.org/PathwayBrowser/#/R-CFA-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70479 https://reactome.org/PathwayBrowser/#/R-CFA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70494 https://reactome.org/PathwayBrowser/#/R-CFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70569 https://reactome.org/PathwayBrowser/#/R-CFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70609 https://reactome.org/PathwayBrowser/#/R-CFA-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70785 https://reactome.org/PathwayBrowser/#/R-CFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70870 https://reactome.org/PathwayBrowser/#/R-CFA-70870 ECHS1 hydrates methacrylyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70903 https://reactome.org/PathwayBrowser/#/R-CFA-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-70906 https://reactome.org/PathwayBrowser/#/R-CFA-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-70982 https://reactome.org/PathwayBrowser/#/R-CFA-70982 FH tetramer hydrates fumarate to L-malate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71146 https://reactome.org/PathwayBrowser/#/R-CFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71296 https://reactome.org/PathwayBrowser/#/R-CFA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71660 https://reactome.org/PathwayBrowser/#/R-CFA-71660 Enolase dimers dehydrates 2PG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71676 https://reactome.org/PathwayBrowser/#/R-CFA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-71732 https://reactome.org/PathwayBrowser/#/R-CFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-71825 https://reactome.org/PathwayBrowser/#/R-CFA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73608 https://reactome.org/PathwayBrowser/#/R-CFA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73797 https://reactome.org/PathwayBrowser/#/R-CFA-73797 FAICAR => IMP + H2O IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-73815 https://reactome.org/PathwayBrowser/#/R-CFA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74059 https://reactome.org/PathwayBrowser/#/R-CFA-74059 PDE6 hydrolyses cGMP to GMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74241 https://reactome.org/PathwayBrowser/#/R-CFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74248 https://reactome.org/PathwayBrowser/#/R-CFA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74733 https://reactome.org/PathwayBrowser/#/R-CFA-74733 Insulin receptor de-phosphorylation IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-74948 https://reactome.org/PathwayBrowser/#/R-CFA-74948 PP2A dephosphorylates p-RHO to RHO IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-75899 https://reactome.org/PathwayBrowser/#/R-CFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-76590 https://reactome.org/PathwayBrowser/#/R-CFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77256 https://reactome.org/PathwayBrowser/#/R-CFA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77277 https://reactome.org/PathwayBrowser/#/R-CFA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77301 https://reactome.org/PathwayBrowser/#/R-CFA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77314 https://reactome.org/PathwayBrowser/#/R-CFA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77325 https://reactome.org/PathwayBrowser/#/R-CFA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77333 https://reactome.org/PathwayBrowser/#/R-CFA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-77344 https://reactome.org/PathwayBrowser/#/R-CFA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-77614 https://reactome.org/PathwayBrowser/#/R-CFA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-77615 https://reactome.org/PathwayBrowser/#/R-CFA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-83677 https://reactome.org/PathwayBrowser/#/R-CFA-83677 C4 deamination of cytidine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848053 https://reactome.org/PathwayBrowser/#/R-CFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848215 https://reactome.org/PathwayBrowser/#/R-CFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848338 https://reactome.org/PathwayBrowser/#/R-CFA-8848338 PNPLA4 hydrolyzes TAG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848339 https://reactome.org/PathwayBrowser/#/R-CFA-8848339 PNPLA5 hydrolyzes TAG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848355 https://reactome.org/PathwayBrowser/#/R-CFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8848484 https://reactome.org/PathwayBrowser/#/R-CFA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8849969 https://reactome.org/PathwayBrowser/#/R-CFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8850594 https://reactome.org/PathwayBrowser/#/R-CFA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-2022884 H2O [Golgi lumen] R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-2022884 H2O [Golgi lumen] R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8852200 https://reactome.org/PathwayBrowser/#/R-CFA-8852200 Inactivation of LCK by PTPN22 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8853379 https://reactome.org/PathwayBrowser/#/R-CFA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-8853686 https://reactome.org/PathwayBrowser/#/R-CFA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8854173 https://reactome.org/PathwayBrowser/#/R-CFA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8854255 https://reactome.org/PathwayBrowser/#/R-CFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8854329 https://reactome.org/PathwayBrowser/#/R-CFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8854604 https://reactome.org/PathwayBrowser/#/R-CFA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8854612 https://reactome.org/PathwayBrowser/#/R-CFA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8855381 https://reactome.org/PathwayBrowser/#/R-CFA-8855381 PTPN22 dephosphorylates ZAP70 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8855490 https://reactome.org/PathwayBrowser/#/R-CFA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8855825 https://reactome.org/PathwayBrowser/#/R-CFA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-8856951 https://reactome.org/PathwayBrowser/#/R-CFA-8856951 PP2A demethylation by PPME1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-8862184 https://reactome.org/PathwayBrowser/#/R-CFA-8862184 USP48 cleaves polyubiquitin IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8862320 https://reactome.org/PathwayBrowser/#/R-CFA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8863804 https://reactome.org/PathwayBrowser/#/R-CFA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8864029 https://reactome.org/PathwayBrowser/#/R-CFA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8864036 https://reactome.org/PathwayBrowser/#/R-CFA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8864125 https://reactome.org/PathwayBrowser/#/R-CFA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-8865667 https://reactome.org/PathwayBrowser/#/R-CFA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8866405 https://reactome.org/PathwayBrowser/#/R-CFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8866542 https://reactome.org/PathwayBrowser/#/R-CFA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8867047 https://reactome.org/PathwayBrowser/#/R-CFA-8867047 PTPN3 dephosphorylates EPS15 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-8867344 https://reactome.org/PathwayBrowser/#/R-CFA-8867344 OMA1 hydrolyses OPA1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8867658 https://reactome.org/PathwayBrowser/#/R-CFA-8867658 PTPN3 dephosphorylates MAPK12 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8868648 https://reactome.org/PathwayBrowser/#/R-CFA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8868658 https://reactome.org/PathwayBrowser/#/R-CFA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8868661 https://reactome.org/PathwayBrowser/#/R-CFA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8869206 https://reactome.org/PathwayBrowser/#/R-CFA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8869425 https://reactome.org/PathwayBrowser/#/R-CFA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8869456 https://reactome.org/PathwayBrowser/#/R-CFA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8869506 https://reactome.org/PathwayBrowser/#/R-CFA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8874435 https://reactome.org/PathwayBrowser/#/R-CFA-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8875443 https://reactome.org/PathwayBrowser/#/R-CFA-8875443 USP8 deubiquitinates LRIG1 IEA Canis familiaris 15377 R-ALL-5668574 H2O [melanosome lumen] R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-8878654 https://reactome.org/PathwayBrowser/#/R-CFA-8878654 ACP6 hydrolyses MYS-LPA IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8878787 https://reactome.org/PathwayBrowser/#/R-CFA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8932633 https://reactome.org/PathwayBrowser/#/R-CFA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8933328 https://reactome.org/PathwayBrowser/#/R-CFA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Canis familiaris 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-893596 https://reactome.org/PathwayBrowser/#/R-CFA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-8937767 https://reactome.org/PathwayBrowser/#/R-CFA-8937767 PTPN11 dephosphorylates RUNX1 IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8940074 https://reactome.org/PathwayBrowser/#/R-CFA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8940388 https://reactome.org/PathwayBrowser/#/R-CFA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8943279 https://reactome.org/PathwayBrowser/#/R-CFA-8943279 GGT dimers hydrolyse GSH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8952137 https://reactome.org/PathwayBrowser/#/R-CFA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8952251 https://reactome.org/PathwayBrowser/#/R-CFA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8953339 https://reactome.org/PathwayBrowser/#/R-CFA-8953339 DNPH1 hydrolyses dGMP IEA Canis familiaris 15377 R-ALL-2022884 H2O [Golgi lumen] R-CFA-8953499 https://reactome.org/PathwayBrowser/#/R-CFA-8953499 IMPAD1 hydrolyses PAP to AMP IEA Canis familiaris 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-CFA-8954398 https://reactome.org/PathwayBrowser/#/R-CFA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8955794 https://reactome.org/PathwayBrowser/#/R-CFA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-8955817 https://reactome.org/PathwayBrowser/#/R-CFA-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-8957389 https://reactome.org/PathwayBrowser/#/R-CFA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8979996 https://reactome.org/PathwayBrowser/#/R-CFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-8980228 https://reactome.org/PathwayBrowser/#/R-CFA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8981637 https://reactome.org/PathwayBrowser/#/R-CFA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-8985594 https://reactome.org/PathwayBrowser/#/R-CFA-8985594 MYO9B inactivates RHOA IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-9008822 https://reactome.org/PathwayBrowser/#/R-CFA-9008822 PPM1D dephosphorylates RUNX2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9013022 https://reactome.org/PathwayBrowser/#/R-CFA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9013111 https://reactome.org/PathwayBrowser/#/R-CFA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9013144 https://reactome.org/PathwayBrowser/#/R-CFA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9013161 https://reactome.org/PathwayBrowser/#/R-CFA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9013437 https://reactome.org/PathwayBrowser/#/R-CFA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9014295 https://reactome.org/PathwayBrowser/#/R-CFA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9014434 https://reactome.org/PathwayBrowser/#/R-CFA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9014641 https://reactome.org/PathwayBrowser/#/R-CFA-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9017488 https://reactome.org/PathwayBrowser/#/R-CFA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018745 https://reactome.org/PathwayBrowser/#/R-CFA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018806 https://reactome.org/PathwayBrowser/#/R-CFA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018814 https://reactome.org/PathwayBrowser/#/R-CFA-9018814 RHOT1 hydrolyzes GTP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018862 https://reactome.org/PathwayBrowser/#/R-CFA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018868 https://reactome.org/PathwayBrowser/#/R-CFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018877 https://reactome.org/PathwayBrowser/#/R-CFA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9018895 https://reactome.org/PathwayBrowser/#/R-CFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020252 https://reactome.org/PathwayBrowser/#/R-CFA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020253 https://reactome.org/PathwayBrowser/#/R-CFA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020257 https://reactome.org/PathwayBrowser/#/R-CFA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020258 https://reactome.org/PathwayBrowser/#/R-CFA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020270 https://reactome.org/PathwayBrowser/#/R-CFA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020271 https://reactome.org/PathwayBrowser/#/R-CFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9020273 https://reactome.org/PathwayBrowser/#/R-CFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9024890 https://reactome.org/PathwayBrowser/#/R-CFA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9024993 https://reactome.org/PathwayBrowser/#/R-CFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15377 R-ALL-141343 H2O [peroxisomal matrix] R-CFA-9033520 https://reactome.org/PathwayBrowser/#/R-CFA-9033520 TYSND1 cleaves TYSND1 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9036727 https://reactome.org/PathwayBrowser/#/R-CFA-9036727 GAA hydrolyzes lysosomal glycogen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-936802 https://reactome.org/PathwayBrowser/#/R-CFA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-936883 https://reactome.org/PathwayBrowser/#/R-CFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-936895 https://reactome.org/PathwayBrowser/#/R-CFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-936897 https://reactome.org/PathwayBrowser/#/R-CFA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-939763 https://reactome.org/PathwayBrowser/#/R-CFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-947531 https://reactome.org/PathwayBrowser/#/R-CFA-947531 Molybdenum ion transfer onto molybdopterin IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-947535 https://reactome.org/PathwayBrowser/#/R-CFA-947535 Cyclisation of GTP to precursor Z IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-947591 https://reactome.org/PathwayBrowser/#/R-CFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9624893 https://reactome.org/PathwayBrowser/#/R-CFA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9629675 https://reactome.org/PathwayBrowser/#/R-CFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9638075 https://reactome.org/PathwayBrowser/#/R-CFA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9638076 https://reactome.org/PathwayBrowser/#/R-CFA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9638078 https://reactome.org/PathwayBrowser/#/R-CFA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9638120 https://reactome.org/PathwayBrowser/#/R-CFA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9644869 https://reactome.org/PathwayBrowser/#/R-CFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9647994 https://reactome.org/PathwayBrowser/#/R-CFA-9647994 RAS proteins are depalmitoylated IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-965067 https://reactome.org/PathwayBrowser/#/R-CFA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9653514 https://reactome.org/PathwayBrowser/#/R-CFA-9653514 USP17L2 deubiquitinates RCE1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9656891 https://reactome.org/PathwayBrowser/#/R-CFA-9656891 OPN1SW binds 11cRAL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9656893 https://reactome.org/PathwayBrowser/#/R-CFA-9656893 OPN1MW binds 11cRAL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9659680 https://reactome.org/PathwayBrowser/#/R-CFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9661417 https://reactome.org/PathwayBrowser/#/R-CFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9667952 https://reactome.org/PathwayBrowser/#/R-CFA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9668419 https://reactome.org/PathwayBrowser/#/R-CFA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-9673053 https://reactome.org/PathwayBrowser/#/R-CFA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-9673054 https://reactome.org/PathwayBrowser/#/R-CFA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9674127 https://reactome.org/PathwayBrowser/#/R-CFA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-9686524 https://reactome.org/PathwayBrowser/#/R-CFA-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9693282 https://reactome.org/PathwayBrowser/#/R-CFA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9698408 https://reactome.org/PathwayBrowser/#/R-CFA-9698408 PTPRJ dephosphorylates active FLT3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9700200 https://reactome.org/PathwayBrowser/#/R-CFA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9701507 https://reactome.org/PathwayBrowser/#/R-CFA-9701507 PTPN6 dephosphorylates JAK3 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-9701565 https://reactome.org/PathwayBrowser/#/R-CFA-9701565 HDACs deacetylate p-STAT3 dimers IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9705507 https://reactome.org/PathwayBrowser/#/R-CFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9706399 https://reactome.org/PathwayBrowser/#/R-CFA-9706399 RHOBTB3 hydrolyzes ATP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9708261 https://reactome.org/PathwayBrowser/#/R-CFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9727567 https://reactome.org/PathwayBrowser/#/R-CFA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9750546 https://reactome.org/PathwayBrowser/#/R-CFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9750555 https://reactome.org/PathwayBrowser/#/R-CFA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9750617 https://reactome.org/PathwayBrowser/#/R-CFA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9750656 https://reactome.org/PathwayBrowser/#/R-CFA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9750942 https://reactome.org/PathwayBrowser/#/R-CFA-9750942 USP14 deubiquitinates NLRC5 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753278 https://reactome.org/PathwayBrowser/#/R-CFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753280 https://reactome.org/PathwayBrowser/#/R-CFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753283 https://reactome.org/PathwayBrowser/#/R-CFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753284 https://reactome.org/PathwayBrowser/#/R-CFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753632 https://reactome.org/PathwayBrowser/#/R-CFA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753634 https://reactome.org/PathwayBrowser/#/R-CFA-9753634 GGT dimers hydrolyse APAP-SG IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9753944 https://reactome.org/PathwayBrowser/#/R-CFA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9754964 https://reactome.org/PathwayBrowser/#/R-CFA-9754964 ADA deamidates RBV IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9755030 https://reactome.org/PathwayBrowser/#/R-CFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9755078 https://reactome.org/PathwayBrowser/#/R-CFA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Canis familiaris 15377 R-ALL-109276 H2O [extracellular region] R-CFA-975594 https://reactome.org/PathwayBrowser/#/R-CFA-975594 PLB1 hydrolyses RPALM to atROL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9759206 https://reactome.org/PathwayBrowser/#/R-CFA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9759454 https://reactome.org/PathwayBrowser/#/R-CFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9759461 https://reactome.org/PathwayBrowser/#/R-CFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-977324 https://reactome.org/PathwayBrowser/#/R-CFA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9794120 https://reactome.org/PathwayBrowser/#/R-CFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9794572 https://reactome.org/PathwayBrowser/#/R-CFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-9825772 https://reactome.org/PathwayBrowser/#/R-CFA-9825772 SIRT1 deacetylates HINT1 dimer IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-983422 https://reactome.org/PathwayBrowser/#/R-CFA-983422 Disassembly of COPII coated vesicle IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9837419 https://reactome.org/PathwayBrowser/#/R-CFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9838004 https://reactome.org/PathwayBrowser/#/R-CFA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9838081 https://reactome.org/PathwayBrowser/#/R-CFA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9838289 https://reactome.org/PathwayBrowser/#/R-CFA-9838289 CLPXP degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9839059 https://reactome.org/PathwayBrowser/#/R-CFA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Canis familiaris 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-CFA-9839072 https://reactome.org/PathwayBrowser/#/R-CFA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9839105 https://reactome.org/PathwayBrowser/#/R-CFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Canis familiaris 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-CFA-9839110 https://reactome.org/PathwayBrowser/#/R-CFA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9839113 https://reactome.org/PathwayBrowser/#/R-CFA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Canis familiaris 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-CFA-9840408 https://reactome.org/PathwayBrowser/#/R-CFA-9840408 OMA1 cleaves DELE1 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9840795 https://reactome.org/PathwayBrowser/#/R-CFA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9840833 https://reactome.org/PathwayBrowser/#/R-CFA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9840884 https://reactome.org/PathwayBrowser/#/R-CFA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9840949 https://reactome.org/PathwayBrowser/#/R-CFA-9840949 ARSA removes sulfate from SM3 IEA Canis familiaris 15377 R-ALL-1605715 H2O [lysosomal lumen] R-CFA-9841189 https://reactome.org/PathwayBrowser/#/R-CFA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9841847 https://reactome.org/PathwayBrowser/#/R-CFA-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9853385 https://reactome.org/PathwayBrowser/#/R-CFA-9853385 PPP1CC dephosphorylates PLK1 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9861626 https://reactome.org/PathwayBrowser/#/R-CFA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9861725 https://reactome.org/PathwayBrowser/#/R-CFA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9865167 https://reactome.org/PathwayBrowser/#/R-CFA-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9865226 https://reactome.org/PathwayBrowser/#/R-CFA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9912636 https://reactome.org/PathwayBrowser/#/R-CFA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9912655 https://reactome.org/PathwayBrowser/#/R-CFA-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9912747 https://reactome.org/PathwayBrowser/#/R-CFA-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9912751 https://reactome.org/PathwayBrowser/#/R-CFA-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9915968 https://reactome.org/PathwayBrowser/#/R-CFA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9915971 https://reactome.org/PathwayBrowser/#/R-CFA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9915986 https://reactome.org/PathwayBrowser/#/R-CFA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-CFA-9915993 https://reactome.org/PathwayBrowser/#/R-CFA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9915994 https://reactome.org/PathwayBrowser/#/R-CFA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9915997 https://reactome.org/PathwayBrowser/#/R-CFA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-9916401 https://reactome.org/PathwayBrowser/#/R-CFA-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Canis familiaris 15377 R-ALL-113521 H2O [mitochondrial matrix] R-CFA-9929439 https://reactome.org/PathwayBrowser/#/R-CFA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-997309 https://reactome.org/PathwayBrowser/#/R-CFA-997309 Dephosphorylation of STAT1 by SHP2 IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-997311 https://reactome.org/PathwayBrowser/#/R-CFA-997311 Dephosphorylation of TYK2 by PTP1B IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-CFA-997314 https://reactome.org/PathwayBrowser/#/R-CFA-997314 Dephosphorylation of JAK1 by SHP1 IEA Canis familiaris 15377 R-ALL-113518 H2O [nucleoplasm] R-CFA-997326 https://reactome.org/PathwayBrowser/#/R-CFA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Canis familiaris 15377 R-ALL-29356 H2O [cytosol] R-DDI-111751 https://reactome.org/PathwayBrowser/#/R-DDI-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-111804 https://reactome.org/PathwayBrowser/#/R-DDI-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-111879 https://reactome.org/PathwayBrowser/#/R-DDI-111879 PIP2 hydrolysis IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-111955 https://reactome.org/PathwayBrowser/#/R-DDI-111955 cAMP hydrolysis by Cam-PDE 1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-111962 https://reactome.org/PathwayBrowser/#/R-DDI-111962 PDE4A,C,D hydrolyse cAMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-112037 https://reactome.org/PathwayBrowser/#/R-DDI-112037 Inactivation of PLC beta IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-113503 https://reactome.org/PathwayBrowser/#/R-DDI-113503 PP2A mediated localization of RB1 protein in chromatin IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1237129 https://reactome.org/PathwayBrowser/#/R-DDI-1237129 Acireductone is created IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1247910 https://reactome.org/PathwayBrowser/#/R-DDI-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1247935 https://reactome.org/PathwayBrowser/#/R-DDI-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-1363274 https://reactome.org/PathwayBrowser/#/R-DDI-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-1363276 https://reactome.org/PathwayBrowser/#/R-DDI-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1369028 https://reactome.org/PathwayBrowser/#/R-DDI-1369028 ABCAs mediate lipid efflux IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1369052 https://reactome.org/PathwayBrowser/#/R-DDI-1369052 ABCAs mediate lipid influx IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1454916 https://reactome.org/PathwayBrowser/#/R-DDI-1454916 The ABCC family mediates organic anion transport IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1454928 https://reactome.org/PathwayBrowser/#/R-DDI-1454928 ABCG4 may mediate cholesterol efflux IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1467457 https://reactome.org/PathwayBrowser/#/R-DDI-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1467466 https://reactome.org/PathwayBrowser/#/R-DDI-1467466 ABCA4 mediates atRAL transport IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1474146 https://reactome.org/PathwayBrowser/#/R-DDI-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482543 https://reactome.org/PathwayBrowser/#/R-DDI-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482612 https://reactome.org/PathwayBrowser/#/R-DDI-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482685 https://reactome.org/PathwayBrowser/#/R-DDI-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482816 https://reactome.org/PathwayBrowser/#/R-DDI-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482825 https://reactome.org/PathwayBrowser/#/R-DDI-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482856 https://reactome.org/PathwayBrowser/#/R-DDI-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482884 https://reactome.org/PathwayBrowser/#/R-DDI-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1482887 https://reactome.org/PathwayBrowser/#/R-DDI-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1483182 https://reactome.org/PathwayBrowser/#/R-DDI-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1483203 https://reactome.org/PathwayBrowser/#/R-DDI-1483203 PA is dephosphorylated to DAG by LPIN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1605624 https://reactome.org/PathwayBrowser/#/R-DDI-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1605632 https://reactome.org/PathwayBrowser/#/R-DDI-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1605736 https://reactome.org/PathwayBrowser/#/R-DDI-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1606312 https://reactome.org/PathwayBrowser/#/R-DDI-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1606583 https://reactome.org/PathwayBrowser/#/R-DDI-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1614524 https://reactome.org/PathwayBrowser/#/R-DDI-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1614583 https://reactome.org/PathwayBrowser/#/R-DDI-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to pyruvate and H2S IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-162425 https://reactome.org/PathwayBrowser/#/R-DDI-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-162857 https://reactome.org/PathwayBrowser/#/R-DDI-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1630306 https://reactome.org/PathwayBrowser/#/R-DDI-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1638053 https://reactome.org/PathwayBrowser/#/R-DDI-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675795 https://reactome.org/PathwayBrowser/#/R-DDI-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675824 https://reactome.org/PathwayBrowser/#/R-DDI-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675836 https://reactome.org/PathwayBrowser/#/R-DDI-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675949 https://reactome.org/PathwayBrowser/#/R-DDI-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675988 https://reactome.org/PathwayBrowser/#/R-DDI-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1675994 https://reactome.org/PathwayBrowser/#/R-DDI-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676065 https://reactome.org/PathwayBrowser/#/R-DDI-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676105 https://reactome.org/PathwayBrowser/#/R-DDI-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676114 https://reactome.org/PathwayBrowser/#/R-DDI-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676124 https://reactome.org/PathwayBrowser/#/R-DDI-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676141 https://reactome.org/PathwayBrowser/#/R-DDI-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676149 https://reactome.org/PathwayBrowser/#/R-DDI-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676177 https://reactome.org/PathwayBrowser/#/R-DDI-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676203 https://reactome.org/PathwayBrowser/#/R-DDI-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1676204 https://reactome.org/PathwayBrowser/#/R-DDI-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1678716 https://reactome.org/PathwayBrowser/#/R-DDI-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1678742 https://reactome.org/PathwayBrowser/#/R-DDI-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-174391 https://reactome.org/PathwayBrowser/#/R-DDI-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-174401 https://reactome.org/PathwayBrowser/#/R-DDI-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-176606 https://reactome.org/PathwayBrowser/#/R-DDI-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-1793186 https://reactome.org/PathwayBrowser/#/R-DDI-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855154 https://reactome.org/PathwayBrowser/#/R-DDI-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855159 https://reactome.org/PathwayBrowser/#/R-DDI-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-1855163 https://reactome.org/PathwayBrowser/#/R-DDI-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855165 https://reactome.org/PathwayBrowser/#/R-DDI-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855166 https://reactome.org/PathwayBrowser/#/R-DDI-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855171 https://reactome.org/PathwayBrowser/#/R-DDI-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855174 https://reactome.org/PathwayBrowser/#/R-DDI-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855177 https://reactome.org/PathwayBrowser/#/R-DDI-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855198 https://reactome.org/PathwayBrowser/#/R-DDI-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-1855200 https://reactome.org/PathwayBrowser/#/R-DDI-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855205 https://reactome.org/PathwayBrowser/#/R-DDI-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855208 https://reactome.org/PathwayBrowser/#/R-DDI-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855210 https://reactome.org/PathwayBrowser/#/R-DDI-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855211 https://reactome.org/PathwayBrowser/#/R-DDI-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855213 https://reactome.org/PathwayBrowser/#/R-DDI-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855214 https://reactome.org/PathwayBrowser/#/R-DDI-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855218 https://reactome.org/PathwayBrowser/#/R-DDI-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855219 https://reactome.org/PathwayBrowser/#/R-DDI-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855221 https://reactome.org/PathwayBrowser/#/R-DDI-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855222 https://reactome.org/PathwayBrowser/#/R-DDI-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-1855225 https://reactome.org/PathwayBrowser/#/R-DDI-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1855232 https://reactome.org/PathwayBrowser/#/R-DDI-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-1861788 https://reactome.org/PathwayBrowser/#/R-DDI-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-189053 https://reactome.org/PathwayBrowser/#/R-DDI-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-189069 https://reactome.org/PathwayBrowser/#/R-DDI-189069 sucrose + H2O => glucose + fructose IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-189102 https://reactome.org/PathwayBrowser/#/R-DDI-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-189488 https://reactome.org/PathwayBrowser/#/R-DDI-189488 UROS transforms HMB to URO3 IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-191101 https://reactome.org/PathwayBrowser/#/R-DDI-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-191108 https://reactome.org/PathwayBrowser/#/R-DDI-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-191116 https://reactome.org/PathwayBrowser/#/R-DDI-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-192331 https://reactome.org/PathwayBrowser/#/R-DDI-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-193362 https://reactome.org/PathwayBrowser/#/R-DDI-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-193535 https://reactome.org/PathwayBrowser/#/R-DDI-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-197186 https://reactome.org/PathwayBrowser/#/R-DDI-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-199456 https://reactome.org/PathwayBrowser/#/R-DDI-199456 PTEN dephosphorylates PIP3 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-199959 https://reactome.org/PathwayBrowser/#/R-DDI-199959 ERKs are inactivated by protein phosphatase 2A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-200661 https://reactome.org/PathwayBrowser/#/R-DDI-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-200740 https://reactome.org/PathwayBrowser/#/R-DDI-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-201035 https://reactome.org/PathwayBrowser/#/R-DDI-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2023971 https://reactome.org/PathwayBrowser/#/R-DDI-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2023973 https://reactome.org/PathwayBrowser/#/R-DDI-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-202407 https://reactome.org/PathwayBrowser/#/R-DDI-202407 PLC-gamma1 hydrolyses PIP2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2029468 https://reactome.org/PathwayBrowser/#/R-DDI-2029468 Conversion of PA into DAG by PAP-1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2029471 https://reactome.org/PathwayBrowser/#/R-DDI-2029471 Hydrolysis of PC to PA by PLD IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 Depalmitoylation of eNOS IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-203797 https://reactome.org/PathwayBrowser/#/R-DDI-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046083 https://reactome.org/PathwayBrowser/#/R-DDI-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046088 https://reactome.org/PathwayBrowser/#/R-DDI-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046090 https://reactome.org/PathwayBrowser/#/R-DDI-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046094 https://reactome.org/PathwayBrowser/#/R-DDI-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046095 https://reactome.org/PathwayBrowser/#/R-DDI-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2046100 https://reactome.org/PathwayBrowser/#/R-DDI-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-2066778 https://reactome.org/PathwayBrowser/#/R-DDI-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-2090037 https://reactome.org/PathwayBrowser/#/R-DDI-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-2090038 https://reactome.org/PathwayBrowser/#/R-DDI-2090038 NAGLU hydrolyses heparan chain(2) IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-2090079 https://reactome.org/PathwayBrowser/#/R-DDI-2090079 GLB1 hydrolyses linker chain(2) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-2105001 https://reactome.org/PathwayBrowser/#/R-DDI-2105001 HEXA cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2161961 https://reactome.org/PathwayBrowser/#/R-DDI-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-2162187 https://reactome.org/PathwayBrowser/#/R-DDI-2162187 COQ6 hydroxylates DHB IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-2162225 https://reactome.org/PathwayBrowser/#/R-DDI-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2393939 https://reactome.org/PathwayBrowser/#/R-DDI-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2408551 https://reactome.org/PathwayBrowser/#/R-DDI-2408551 SeMet is converted to AdoSeMet by MAT IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-2529015 https://reactome.org/PathwayBrowser/#/R-DDI-2529015 Dephosphorylation of CK2-modified condensin I IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-265783 https://reactome.org/PathwayBrowser/#/R-DDI-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-266051 https://reactome.org/PathwayBrowser/#/R-DDI-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-266070 https://reactome.org/PathwayBrowser/#/R-DDI-266070 LTC4 is exported from the cytosol by ABCC1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-266072 https://reactome.org/PathwayBrowser/#/R-DDI-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-266082 https://reactome.org/PathwayBrowser/#/R-DDI-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-2995330 https://reactome.org/PathwayBrowser/#/R-DDI-2995330 COX10 transforms heme to heme O IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-2995334 https://reactome.org/PathwayBrowser/#/R-DDI-2995334 COX15 transforms heme O to heme A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-3095901 https://reactome.org/PathwayBrowser/#/R-DDI-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-3322995 https://reactome.org/PathwayBrowser/#/R-DDI-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-3341343 https://reactome.org/PathwayBrowser/#/R-DDI-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-3343700 https://reactome.org/PathwayBrowser/#/R-DDI-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-3697882 https://reactome.org/PathwayBrowser/#/R-DDI-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-3697894 https://reactome.org/PathwayBrowser/#/R-DDI-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-372519 https://reactome.org/PathwayBrowser/#/R-DDI-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-3769447 https://reactome.org/PathwayBrowser/#/R-DDI-3769447 HDAC1:2-containing complex deacetylate histones IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-3782637 https://reactome.org/PathwayBrowser/#/R-DDI-3782637 HDAC8 deacetylates histones IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-3782655 https://reactome.org/PathwayBrowser/#/R-DDI-3782655 HDAC10 deacetylates histone IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-382560 https://reactome.org/PathwayBrowser/#/R-DDI-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-382575 https://reactome.org/PathwayBrowser/#/R-DDI-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-383190 https://reactome.org/PathwayBrowser/#/R-DDI-383190 HCO3- transport through ion channel IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-389986 https://reactome.org/PathwayBrowser/#/R-DDI-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-390252 https://reactome.org/PathwayBrowser/#/R-DDI-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-390329 https://reactome.org/PathwayBrowser/#/R-DDI-390329 Dephosphorylation of AKT by PP2A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-390393 https://reactome.org/PathwayBrowser/#/R-DDI-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-399998 https://reactome.org/PathwayBrowser/#/R-DDI-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-418553 https://reactome.org/PathwayBrowser/#/R-DDI-418553 cAMP degradation by Phosphodiesterases IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-428262 https://reactome.org/PathwayBrowser/#/R-DDI-428262 ACER3 hydrolyzes phytoceramide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-428664 https://reactome.org/PathwayBrowser/#/R-DDI-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-428690 https://reactome.org/PathwayBrowser/#/R-DDI-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-428696 https://reactome.org/PathwayBrowser/#/R-DDI-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-429860 https://reactome.org/PathwayBrowser/#/R-DDI-429860 DCP1-DCP2 complex decaps mRNA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-430028 https://reactome.org/PathwayBrowser/#/R-DDI-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-432010 https://reactome.org/PathwayBrowser/#/R-DDI-432010 Aquaporin-1 passively transports water into cell IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-432010 https://reactome.org/PathwayBrowser/#/R-DDI-432010 Aquaporin-1 passively transports water into cell IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-432054 https://reactome.org/PathwayBrowser/#/R-DDI-432054 Aquaporin-1 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-432054 https://reactome.org/PathwayBrowser/#/R-DDI-432054 Aquaporin-1 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-432065 https://reactome.org/PathwayBrowser/#/R-DDI-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-432065 https://reactome.org/PathwayBrowser/#/R-DDI-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-432067 https://reactome.org/PathwayBrowser/#/R-DDI-432067 Aquaporin-4 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-432067 https://reactome.org/PathwayBrowser/#/R-DDI-432067 Aquaporin-4 passively transports water out of cell IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-449937 https://reactome.org/PathwayBrowser/#/R-DDI-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-452036 https://reactome.org/PathwayBrowser/#/R-DDI-452036 arginine + H2O => ornithine + urea [ARG2] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-507868 https://reactome.org/PathwayBrowser/#/R-DDI-507868 Aquaporins passively transport water into cells IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-507868 https://reactome.org/PathwayBrowser/#/R-DDI-507868 Aquaporins passively transport water into cells IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-507870 https://reactome.org/PathwayBrowser/#/R-DDI-507870 Aquaporins passively transport water out of cells IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-507870 https://reactome.org/PathwayBrowser/#/R-DDI-507870 Aquaporins passively transport water out of cells IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5221130 https://reactome.org/PathwayBrowser/#/R-DDI-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5223313 https://reactome.org/PathwayBrowser/#/R-DDI-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5251955 https://reactome.org/PathwayBrowser/#/R-DDI-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5251959 https://reactome.org/PathwayBrowser/#/R-DDI-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5251989 https://reactome.org/PathwayBrowser/#/R-DDI-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5433074 https://reactome.org/PathwayBrowser/#/R-DDI-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5603114 https://reactome.org/PathwayBrowser/#/R-DDI-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5607735 https://reactome.org/PathwayBrowser/#/R-DDI-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5631885 https://reactome.org/PathwayBrowser/#/R-DDI-5631885 PRDX1 overoxidizes IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5649705 https://reactome.org/PathwayBrowser/#/R-DDI-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5651828 https://reactome.org/PathwayBrowser/#/R-DDI-5651828 PARG dePARylates PARP1,PARP2 IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-5659861 https://reactome.org/PathwayBrowser/#/R-DDI-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Dictyostelium discoideum 15377 R-ALL-5668574 H2O [melanosome lumen] R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5675373 https://reactome.org/PathwayBrowser/#/R-DDI-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5675376 https://reactome.org/PathwayBrowser/#/R-DDI-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5676637 https://reactome.org/PathwayBrowser/#/R-DDI-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5678706 https://reactome.org/PathwayBrowser/#/R-DDI-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5678863 https://reactome.org/PathwayBrowser/#/R-DDI-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5679041 https://reactome.org/PathwayBrowser/#/R-DDI-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5682285 https://reactome.org/PathwayBrowser/#/R-DDI-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5683405 https://reactome.org/PathwayBrowser/#/R-DDI-5683405 PPP5C dephosphorylates TP53BP1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5683714 https://reactome.org/PathwayBrowser/#/R-DDI-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Dictyostelium discoideum 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-DDI-5684864 https://reactome.org/PathwayBrowser/#/R-DDI-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5688797 https://reactome.org/PathwayBrowser/#/R-DDI-5688797 ATXN3 family cleave Ub chains IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5689000 https://reactome.org/PathwayBrowser/#/R-DDI-5689000 AADAC deacetylates PHEN IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5689950 https://reactome.org/PathwayBrowser/#/R-DDI-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690043 https://reactome.org/PathwayBrowser/#/R-DDI-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-5690066 https://reactome.org/PathwayBrowser/#/R-DDI-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5690080 https://reactome.org/PathwayBrowser/#/R-DDI-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690152 https://reactome.org/PathwayBrowser/#/R-DDI-5690152 USP5 cleaves polyubiquitin IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5690157 https://reactome.org/PathwayBrowser/#/R-DDI-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690159 https://reactome.org/PathwayBrowser/#/R-DDI-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690319 https://reactome.org/PathwayBrowser/#/R-DDI-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-5690517 https://reactome.org/PathwayBrowser/#/R-DDI-5690517 PPT1 hydrolyses palmitoylated proteins IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5690808 https://reactome.org/PathwayBrowser/#/R-DDI-5690808 UCHL3, SENP8 cleave NEDD8 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5691381 https://reactome.org/PathwayBrowser/#/R-DDI-5691381 MYSM1 deubiquitinates Histone H2A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5691512 https://reactome.org/PathwayBrowser/#/R-DDI-5691512 APEH hydrolyses NAc-Ser-protein IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5692462 https://reactome.org/PathwayBrowser/#/R-DDI-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5692480 https://reactome.org/PathwayBrowser/#/R-DDI-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-5693346 https://reactome.org/PathwayBrowser/#/R-DDI-5693346 CECRI deaminates Ade-Rib to Ino IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-5693724 https://reactome.org/PathwayBrowser/#/R-DDI-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-5693807 https://reactome.org/PathwayBrowser/#/R-DDI-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-5694137 https://reactome.org/PathwayBrowser/#/R-DDI-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5694421 https://reactome.org/PathwayBrowser/#/R-DDI-5694421 PP6 dephosphorylates SEC24 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5694485 https://reactome.org/PathwayBrowser/#/R-DDI-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5696564 https://reactome.org/PathwayBrowser/#/R-DDI-5696564 USP25 deubiquitinates DDX58 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-5696600 https://reactome.org/PathwayBrowser/#/R-DDI-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5696605 https://reactome.org/PathwayBrowser/#/R-DDI-5696605 USP12, USP26 deubiquitinate AR IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5696958 https://reactome.org/PathwayBrowser/#/R-DDI-5696958 USP44 deubiquitinates CDC20 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-5696960 https://reactome.org/PathwayBrowser/#/R-DDI-5696960 USP49 deubiquitinates H2B IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6781779 https://reactome.org/PathwayBrowser/#/R-DDI-6781779 USP13 deubiquitinates BECN1,USP10 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6781814 https://reactome.org/PathwayBrowser/#/R-DDI-6781814 USP19 deubiquitinates RNF123 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-6782069 https://reactome.org/PathwayBrowser/#/R-DDI-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-6782820 https://reactome.org/PathwayBrowser/#/R-DDI-6782820 USP17 deubiquitinates SUDS3 IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-6783177 https://reactome.org/PathwayBrowser/#/R-DDI-6783177 USP21 deubiquitinates GATA3,IL33 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6786650 https://reactome.org/PathwayBrowser/#/R-DDI-6786650 DDHD1,2 hydrolyse PA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6787632 https://reactome.org/PathwayBrowser/#/R-DDI-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Dictyostelium discoideum 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-6789310 https://reactome.org/PathwayBrowser/#/R-DDI-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6797627 https://reactome.org/PathwayBrowser/#/R-DDI-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-6797630 https://reactome.org/PathwayBrowser/#/R-DDI-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-6797955 https://reactome.org/PathwayBrowser/#/R-DDI-6797955 ALDH7A1 oxidises BETALD to BET IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6799545 https://reactome.org/PathwayBrowser/#/R-DDI-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-6799581 https://reactome.org/PathwayBrowser/#/R-DDI-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6799604 https://reactome.org/PathwayBrowser/#/R-DDI-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-6801462 https://reactome.org/PathwayBrowser/#/R-DDI-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-6807118 https://reactome.org/PathwayBrowser/#/R-DDI-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6807206 https://reactome.org/PathwayBrowser/#/R-DDI-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6809320 https://reactome.org/PathwayBrowser/#/R-DDI-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6809325 https://reactome.org/PathwayBrowser/#/R-DDI-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6809720 https://reactome.org/PathwayBrowser/#/R-DDI-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6809777 https://reactome.org/PathwayBrowser/#/R-DDI-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6809778 https://reactome.org/PathwayBrowser/#/R-DDI-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6811504 https://reactome.org/PathwayBrowser/#/R-DDI-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6813720 https://reactome.org/PathwayBrowser/#/R-DDI-6813720 NCEH1 hydrolyzes cholesterol esters IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-6814797 https://reactome.org/PathwayBrowser/#/R-DDI-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70262 https://reactome.org/PathwayBrowser/#/R-DDI-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70479 https://reactome.org/PathwayBrowser/#/R-DDI-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70494 https://reactome.org/PathwayBrowser/#/R-DDI-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70569 https://reactome.org/PathwayBrowser/#/R-DDI-70569 arginine + H2O => ornithine + urea [ARG1] IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70785 https://reactome.org/PathwayBrowser/#/R-DDI-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70870 https://reactome.org/PathwayBrowser/#/R-DDI-70870 ECHS1 hydrates methacrylyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70903 https://reactome.org/PathwayBrowser/#/R-DDI-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-70906 https://reactome.org/PathwayBrowser/#/R-DDI-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-70982 https://reactome.org/PathwayBrowser/#/R-DDI-70982 FH tetramer hydrates fumarate to L-malate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71146 https://reactome.org/PathwayBrowser/#/R-DDI-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71296 https://reactome.org/PathwayBrowser/#/R-DDI-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71660 https://reactome.org/PathwayBrowser/#/R-DDI-71660 Enolase dimers dehydrates 2PG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-71732 https://reactome.org/PathwayBrowser/#/R-DDI-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73608 https://reactome.org/PathwayBrowser/#/R-DDI-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73797 https://reactome.org/PathwayBrowser/#/R-DDI-73797 FAICAR => IMP + H2O IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-74241 https://reactome.org/PathwayBrowser/#/R-DDI-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-74248 https://reactome.org/PathwayBrowser/#/R-DDI-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-75899 https://reactome.org/PathwayBrowser/#/R-DDI-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-76590 https://reactome.org/PathwayBrowser/#/R-DDI-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-77256 https://reactome.org/PathwayBrowser/#/R-DDI-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-77314 https://reactome.org/PathwayBrowser/#/R-DDI-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-77325 https://reactome.org/PathwayBrowser/#/R-DDI-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-77333 https://reactome.org/PathwayBrowser/#/R-DDI-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-77344 https://reactome.org/PathwayBrowser/#/R-DDI-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8848053 https://reactome.org/PathwayBrowser/#/R-DDI-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8848215 https://reactome.org/PathwayBrowser/#/R-DDI-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8849969 https://reactome.org/PathwayBrowser/#/R-DDI-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8853379 https://reactome.org/PathwayBrowser/#/R-DDI-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-8853686 https://reactome.org/PathwayBrowser/#/R-DDI-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8854173 https://reactome.org/PathwayBrowser/#/R-DDI-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8854255 https://reactome.org/PathwayBrowser/#/R-DDI-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8854329 https://reactome.org/PathwayBrowser/#/R-DDI-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8854604 https://reactome.org/PathwayBrowser/#/R-DDI-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8854612 https://reactome.org/PathwayBrowser/#/R-DDI-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-8855490 https://reactome.org/PathwayBrowser/#/R-DDI-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-8856951 https://reactome.org/PathwayBrowser/#/R-DDI-8856951 PP2A demethylation by PPME1 IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-8862320 https://reactome.org/PathwayBrowser/#/R-DDI-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-8867344 https://reactome.org/PathwayBrowser/#/R-DDI-8867344 OMA1 hydrolyses OPA1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8874435 https://reactome.org/PathwayBrowser/#/R-DDI-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Dictyostelium discoideum 15377 R-ALL-5668574 H2O [melanosome lumen] R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-8878654 https://reactome.org/PathwayBrowser/#/R-DDI-8878654 ACP6 hydrolyses MYS-LPA IEA Dictyostelium discoideum 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-893596 https://reactome.org/PathwayBrowser/#/R-DDI-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8937442 https://reactome.org/PathwayBrowser/#/R-DDI-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-8940388 https://reactome.org/PathwayBrowser/#/R-DDI-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8952137 https://reactome.org/PathwayBrowser/#/R-DDI-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Dictyostelium discoideum 15377 R-ALL-2022884 H2O [Golgi lumen] R-DDI-8953499 https://reactome.org/PathwayBrowser/#/R-DDI-8953499 IMPAD1 hydrolyses PAP to AMP IEA Dictyostelium discoideum 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DDI-8954398 https://reactome.org/PathwayBrowser/#/R-DDI-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-8955817 https://reactome.org/PathwayBrowser/#/R-DDI-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-8957389 https://reactome.org/PathwayBrowser/#/R-DDI-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-8979996 https://reactome.org/PathwayBrowser/#/R-DDI-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9013144 https://reactome.org/PathwayBrowser/#/R-DDI-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9013161 https://reactome.org/PathwayBrowser/#/R-DDI-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9014295 https://reactome.org/PathwayBrowser/#/R-DDI-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9014641 https://reactome.org/PathwayBrowser/#/R-DDI-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9017488 https://reactome.org/PathwayBrowser/#/R-DDI-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018745 https://reactome.org/PathwayBrowser/#/R-DDI-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018806 https://reactome.org/PathwayBrowser/#/R-DDI-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018814 https://reactome.org/PathwayBrowser/#/R-DDI-9018814 RHOT1 hydrolyzes GTP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018826 https://reactome.org/PathwayBrowser/#/R-DDI-9018826 RHOT2 hydrolyzes GTP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018862 https://reactome.org/PathwayBrowser/#/R-DDI-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9018877 https://reactome.org/PathwayBrowser/#/R-DDI-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9020252 https://reactome.org/PathwayBrowser/#/R-DDI-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9020253 https://reactome.org/PathwayBrowser/#/R-DDI-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9020257 https://reactome.org/PathwayBrowser/#/R-DDI-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9020258 https://reactome.org/PathwayBrowser/#/R-DDI-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9020270 https://reactome.org/PathwayBrowser/#/R-DDI-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9024890 https://reactome.org/PathwayBrowser/#/R-DDI-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9024993 https://reactome.org/PathwayBrowser/#/R-DDI-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9033491 https://reactome.org/PathwayBrowser/#/R-DDI-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Dictyostelium discoideum 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DDI-9033520 https://reactome.org/PathwayBrowser/#/R-DDI-9033520 TYSND1 cleaves TYSND1 IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-9036727 https://reactome.org/PathwayBrowser/#/R-DDI-9036727 GAA hydrolyzes lysosomal glycogen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-936895 https://reactome.org/PathwayBrowser/#/R-DDI-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-939763 https://reactome.org/PathwayBrowser/#/R-DDI-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-947531 https://reactome.org/PathwayBrowser/#/R-DDI-947531 Molybdenum ion transfer onto molybdopterin IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-947535 https://reactome.org/PathwayBrowser/#/R-DDI-947535 Cyclisation of GTP to precursor Z IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-947591 https://reactome.org/PathwayBrowser/#/R-DDI-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9629675 https://reactome.org/PathwayBrowser/#/R-DDI-9629675 PDE3A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9635739 https://reactome.org/PathwayBrowser/#/R-DDI-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-9638075 https://reactome.org/PathwayBrowser/#/R-DDI-9638075 HEXB cleaves the terminal GalNAc from DS IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-9638076 https://reactome.org/PathwayBrowser/#/R-DDI-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-9638078 https://reactome.org/PathwayBrowser/#/R-DDI-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9644869 https://reactome.org/PathwayBrowser/#/R-DDI-9644869 p-S54-PDE4B hydrolyses cAMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9659680 https://reactome.org/PathwayBrowser/#/R-DDI-9659680 ABCB1 transports xenobiotics out of the cell IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9661417 https://reactome.org/PathwayBrowser/#/R-DDI-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9668419 https://reactome.org/PathwayBrowser/#/R-DDI-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-9673053 https://reactome.org/PathwayBrowser/#/R-DDI-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DDI-9673054 https://reactome.org/PathwayBrowser/#/R-DDI-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-9701565 https://reactome.org/PathwayBrowser/#/R-DDI-9701565 HDACs deacetylate p-STAT3 dimers IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9705507 https://reactome.org/PathwayBrowser/#/R-DDI-9705507 PDE3B hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9706399 https://reactome.org/PathwayBrowser/#/R-DDI-9706399 RHOBTB3 hydrolyzes ATP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9708261 https://reactome.org/PathwayBrowser/#/R-DDI-9708261 PDE4A hydrolyses cAMP to AMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9727567 https://reactome.org/PathwayBrowser/#/R-DDI-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9750546 https://reactome.org/PathwayBrowser/#/R-DDI-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9750656 https://reactome.org/PathwayBrowser/#/R-DDI-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9750942 https://reactome.org/PathwayBrowser/#/R-DDI-9750942 USP14 deubiquitinates NLRC5 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753278 https://reactome.org/PathwayBrowser/#/R-DDI-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753280 https://reactome.org/PathwayBrowser/#/R-DDI-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753283 https://reactome.org/PathwayBrowser/#/R-DDI-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753284 https://reactome.org/PathwayBrowser/#/R-DDI-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753632 https://reactome.org/PathwayBrowser/#/R-DDI-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9753944 https://reactome.org/PathwayBrowser/#/R-DDI-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9754964 https://reactome.org/PathwayBrowser/#/R-DDI-9754964 ADA deamidates RBV IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9755030 https://reactome.org/PathwayBrowser/#/R-DDI-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9755078 https://reactome.org/PathwayBrowser/#/R-DDI-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9759206 https://reactome.org/PathwayBrowser/#/R-DDI-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9759454 https://reactome.org/PathwayBrowser/#/R-DDI-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9759461 https://reactome.org/PathwayBrowser/#/R-DDI-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-977324 https://reactome.org/PathwayBrowser/#/R-DDI-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9794120 https://reactome.org/PathwayBrowser/#/R-DDI-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9794572 https://reactome.org/PathwayBrowser/#/R-DDI-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Dictyostelium discoideum 15377 R-ALL-113518 H2O [nucleoplasm] R-DDI-9825772 https://reactome.org/PathwayBrowser/#/R-DDI-9825772 SIRT1 deacetylates HINT1 dimer IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9837419 https://reactome.org/PathwayBrowser/#/R-DDI-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-9838004 https://reactome.org/PathwayBrowser/#/R-DDI-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-9838081 https://reactome.org/PathwayBrowser/#/R-DDI-9838081 LONP1 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-9839105 https://reactome.org/PathwayBrowser/#/R-DDI-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Dictyostelium discoideum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DDI-9839113 https://reactome.org/PathwayBrowser/#/R-DDI-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Dictyostelium discoideum 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DDI-9841189 https://reactome.org/PathwayBrowser/#/R-DDI-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9853385 https://reactome.org/PathwayBrowser/#/R-DDI-9853385 PPP1CC dephosphorylates PLK1 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9912636 https://reactome.org/PathwayBrowser/#/R-DDI-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9912655 https://reactome.org/PathwayBrowser/#/R-DDI-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9912747 https://reactome.org/PathwayBrowser/#/R-DDI-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9912751 https://reactome.org/PathwayBrowser/#/R-DDI-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9915968 https://reactome.org/PathwayBrowser/#/R-DDI-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9915971 https://reactome.org/PathwayBrowser/#/R-DDI-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9915986 https://reactome.org/PathwayBrowser/#/R-DDI-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9915994 https://reactome.org/PathwayBrowser/#/R-DDI-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9915997 https://reactome.org/PathwayBrowser/#/R-DDI-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Dictyostelium discoideum 15377 R-ALL-29356 H2O [cytosol] R-DDI-9916401 https://reactome.org/PathwayBrowser/#/R-DDI-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Dictyostelium discoideum 15377 R-ALL-109276 H2O [extracellular region] R-DME-109278 https://reactome.org/PathwayBrowser/#/R-DME-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-109291 https://reactome.org/PathwayBrowser/#/R-DME-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-109449 https://reactome.org/PathwayBrowser/#/R-DME-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-111751 https://reactome.org/PathwayBrowser/#/R-DME-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-111804 https://reactome.org/PathwayBrowser/#/R-DME-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-111879 https://reactome.org/PathwayBrowser/#/R-DME-111879 PIP2 hydrolysis IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-111955 https://reactome.org/PathwayBrowser/#/R-DME-111955 cAMP hydrolysis by Cam-PDE 1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-111962 https://reactome.org/PathwayBrowser/#/R-DME-111962 PDE4A,C,D hydrolyse cAMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-112037 https://reactome.org/PathwayBrowser/#/R-DME-112037 Inactivation of PLC beta IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1237129 https://reactome.org/PathwayBrowser/#/R-DME-1237129 Acireductone is created IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1247910 https://reactome.org/PathwayBrowser/#/R-DME-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1247935 https://reactome.org/PathwayBrowser/#/R-DME-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-1363274 https://reactome.org/PathwayBrowser/#/R-DME-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-1363276 https://reactome.org/PathwayBrowser/#/R-DME-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1369065 https://reactome.org/PathwayBrowser/#/R-DME-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1454916 https://reactome.org/PathwayBrowser/#/R-DME-1454916 The ABCC family mediates organic anion transport IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1454928 https://reactome.org/PathwayBrowser/#/R-DME-1454928 ABCG4 may mediate cholesterol efflux IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1467466 https://reactome.org/PathwayBrowser/#/R-DME-1467466 ABCA4 mediates atRAL transport IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1474146 https://reactome.org/PathwayBrowser/#/R-DME-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482604 https://reactome.org/PathwayBrowser/#/R-DME-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482656 https://reactome.org/PathwayBrowser/#/R-DME-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482679 https://reactome.org/PathwayBrowser/#/R-DME-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482776 https://reactome.org/PathwayBrowser/#/R-DME-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482777 https://reactome.org/PathwayBrowser/#/R-DME-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482811 https://reactome.org/PathwayBrowser/#/R-DME-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482816 https://reactome.org/PathwayBrowser/#/R-DME-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482856 https://reactome.org/PathwayBrowser/#/R-DME-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482868 https://reactome.org/PathwayBrowser/#/R-DME-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482884 https://reactome.org/PathwayBrowser/#/R-DME-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482887 https://reactome.org/PathwayBrowser/#/R-DME-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482900 https://reactome.org/PathwayBrowser/#/R-DME-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1482907 https://reactome.org/PathwayBrowser/#/R-DME-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1483096 https://reactome.org/PathwayBrowser/#/R-DME-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1483159 https://reactome.org/PathwayBrowser/#/R-DME-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1483182 https://reactome.org/PathwayBrowser/#/R-DME-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1483203 https://reactome.org/PathwayBrowser/#/R-DME-1483203 PA is dephosphorylated to DAG by LPIN IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-159425 https://reactome.org/PathwayBrowser/#/R-DME-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602368 https://reactome.org/PathwayBrowser/#/R-DME-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602374 https://reactome.org/PathwayBrowser/#/R-DME-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602377 https://reactome.org/PathwayBrowser/#/R-DME-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602398 https://reactome.org/PathwayBrowser/#/R-DME-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602399 https://reactome.org/PathwayBrowser/#/R-DME-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602417 https://reactome.org/PathwayBrowser/#/R-DME-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-1602446 https://reactome.org/PathwayBrowser/#/R-DME-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1605591 https://reactome.org/PathwayBrowser/#/R-DME-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1605624 https://reactome.org/PathwayBrowser/#/R-DME-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1605632 https://reactome.org/PathwayBrowser/#/R-DME-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1606312 https://reactome.org/PathwayBrowser/#/R-DME-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1606583 https://reactome.org/PathwayBrowser/#/R-DME-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1614524 https://reactome.org/PathwayBrowser/#/R-DME-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1614583 https://reactome.org/PathwayBrowser/#/R-DME-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to pyruvate and H2S IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-162857 https://reactome.org/PathwayBrowser/#/R-DME-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1630306 https://reactome.org/PathwayBrowser/#/R-DME-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1638032 https://reactome.org/PathwayBrowser/#/R-DME-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1638053 https://reactome.org/PathwayBrowser/#/R-DME-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-164832 https://reactome.org/PathwayBrowser/#/R-DME-164832 ATPase synthesizes ATP IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1667005 https://reactome.org/PathwayBrowser/#/R-DME-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675795 https://reactome.org/PathwayBrowser/#/R-DME-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675824 https://reactome.org/PathwayBrowser/#/R-DME-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675836 https://reactome.org/PathwayBrowser/#/R-DME-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675949 https://reactome.org/PathwayBrowser/#/R-DME-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675988 https://reactome.org/PathwayBrowser/#/R-DME-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1675994 https://reactome.org/PathwayBrowser/#/R-DME-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676065 https://reactome.org/PathwayBrowser/#/R-DME-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676105 https://reactome.org/PathwayBrowser/#/R-DME-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676114 https://reactome.org/PathwayBrowser/#/R-DME-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676124 https://reactome.org/PathwayBrowser/#/R-DME-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676141 https://reactome.org/PathwayBrowser/#/R-DME-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676149 https://reactome.org/PathwayBrowser/#/R-DME-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676162 https://reactome.org/PathwayBrowser/#/R-DME-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676164 https://reactome.org/PathwayBrowser/#/R-DME-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676177 https://reactome.org/PathwayBrowser/#/R-DME-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1676203 https://reactome.org/PathwayBrowser/#/R-DME-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1678650 https://reactome.org/PathwayBrowser/#/R-DME-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1678708 https://reactome.org/PathwayBrowser/#/R-DME-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1678716 https://reactome.org/PathwayBrowser/#/R-DME-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1678742 https://reactome.org/PathwayBrowser/#/R-DME-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1678854 https://reactome.org/PathwayBrowser/#/R-DME-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-170153 https://reactome.org/PathwayBrowser/#/R-DME-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-170158 https://reactome.org/PathwayBrowser/#/R-DME-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-170161 https://reactome.org/PathwayBrowser/#/R-DME-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-174110 https://reactome.org/PathwayBrowser/#/R-DME-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-174124 https://reactome.org/PathwayBrowser/#/R-DME-174124 Dephosphorylation of phospho-Cdh1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-174401 https://reactome.org/PathwayBrowser/#/R-DME-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-176606 https://reactome.org/PathwayBrowser/#/R-DME-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-177923 https://reactome.org/PathwayBrowser/#/R-DME-177923 Sustained activation of SRC kinase by SHP2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-177924 https://reactome.org/PathwayBrowser/#/R-DME-177924 Dephosphorylation of Gab1 by SHP2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-177935 https://reactome.org/PathwayBrowser/#/R-DME-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1793182 https://reactome.org/PathwayBrowser/#/R-DME-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-1793186 https://reactome.org/PathwayBrowser/#/R-DME-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855154 https://reactome.org/PathwayBrowser/#/R-DME-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855165 https://reactome.org/PathwayBrowser/#/R-DME-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855166 https://reactome.org/PathwayBrowser/#/R-DME-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855174 https://reactome.org/PathwayBrowser/#/R-DME-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855177 https://reactome.org/PathwayBrowser/#/R-DME-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855180 https://reactome.org/PathwayBrowser/#/R-DME-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855198 https://reactome.org/PathwayBrowser/#/R-DME-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855202 https://reactome.org/PathwayBrowser/#/R-DME-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855205 https://reactome.org/PathwayBrowser/#/R-DME-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855208 https://reactome.org/PathwayBrowser/#/R-DME-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855210 https://reactome.org/PathwayBrowser/#/R-DME-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855211 https://reactome.org/PathwayBrowser/#/R-DME-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855213 https://reactome.org/PathwayBrowser/#/R-DME-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855214 https://reactome.org/PathwayBrowser/#/R-DME-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855218 https://reactome.org/PathwayBrowser/#/R-DME-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855221 https://reactome.org/PathwayBrowser/#/R-DME-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855222 https://reactome.org/PathwayBrowser/#/R-DME-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1855232 https://reactome.org/PathwayBrowser/#/R-DME-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1861788 https://reactome.org/PathwayBrowser/#/R-DME-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-1861789 https://reactome.org/PathwayBrowser/#/R-DME-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-188979 https://reactome.org/PathwayBrowser/#/R-DME-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-189062 https://reactome.org/PathwayBrowser/#/R-DME-189062 lactose + H2O => D-glucose + D-galactose IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-189406 https://reactome.org/PathwayBrowser/#/R-DME-189406 4 PBGs bind to form HMB IEA Drosophila melanogaster 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-189488 https://reactome.org/PathwayBrowser/#/R-DME-189488 UROS transforms HMB to URO3 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-191114 https://reactome.org/PathwayBrowser/#/R-DME-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-192331 https://reactome.org/PathwayBrowser/#/R-DME-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-192417 https://reactome.org/PathwayBrowser/#/R-DME-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-192425 https://reactome.org/PathwayBrowser/#/R-DME-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-192430 https://reactome.org/PathwayBrowser/#/R-DME-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-192475 https://reactome.org/PathwayBrowser/#/R-DME-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-193535 https://reactome.org/PathwayBrowser/#/R-DME-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193711 https://reactome.org/PathwayBrowser/#/R-DME-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193727 https://reactome.org/PathwayBrowser/#/R-DME-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193743 https://reactome.org/PathwayBrowser/#/R-DME-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-193766 https://reactome.org/PathwayBrowser/#/R-DME-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-197186 https://reactome.org/PathwayBrowser/#/R-DME-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-199425 https://reactome.org/PathwayBrowser/#/R-DME-199425 PHLPP dephosphorylates S473 in AKT IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-199456 https://reactome.org/PathwayBrowser/#/R-DME-199456 PTEN dephosphorylates PIP3 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-199959 https://reactome.org/PathwayBrowser/#/R-DME-199959 ERKs are inactivated by protein phosphatase 2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-200661 https://reactome.org/PathwayBrowser/#/R-DME-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-200740 https://reactome.org/PathwayBrowser/#/R-DME-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-201035 https://reactome.org/PathwayBrowser/#/R-DME-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022368 https://reactome.org/PathwayBrowser/#/R-DME-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022396 https://reactome.org/PathwayBrowser/#/R-DME-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022398 https://reactome.org/PathwayBrowser/#/R-DME-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022399 https://reactome.org/PathwayBrowser/#/R-DME-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022403 https://reactome.org/PathwayBrowser/#/R-DME-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022405 https://reactome.org/PathwayBrowser/#/R-DME-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2022412 https://reactome.org/PathwayBrowser/#/R-DME-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-ALL-2022884 H2O [Golgi lumen] R-DME-2022887 https://reactome.org/PathwayBrowser/#/R-DME-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2023971 https://reactome.org/PathwayBrowser/#/R-DME-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2023973 https://reactome.org/PathwayBrowser/#/R-DME-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-202407 https://reactome.org/PathwayBrowser/#/R-DME-202407 PLC-gamma1 hydrolyses PIP2 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2028294 https://reactome.org/PathwayBrowser/#/R-DME-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2029468 https://reactome.org/PathwayBrowser/#/R-DME-2029468 Conversion of PA into DAG by PAP-1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2029471 https://reactome.org/PathwayBrowser/#/R-DME-2029471 Hydrolysis of PC to PA by PLD IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2029475 https://reactome.org/PathwayBrowser/#/R-DME-2029475 Production of AA by iPLA2 upon FCGR activation IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 Depalmitoylation of eNOS IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-203797 https://reactome.org/PathwayBrowser/#/R-DME-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-204169 https://reactome.org/PathwayBrowser/#/R-DME-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046083 https://reactome.org/PathwayBrowser/#/R-DME-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046088 https://reactome.org/PathwayBrowser/#/R-DME-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046090 https://reactome.org/PathwayBrowser/#/R-DME-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046094 https://reactome.org/PathwayBrowser/#/R-DME-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046095 https://reactome.org/PathwayBrowser/#/R-DME-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2046100 https://reactome.org/PathwayBrowser/#/R-DME-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2065355 https://reactome.org/PathwayBrowser/#/R-DME-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-2065357 https://reactome.org/PathwayBrowser/#/R-DME-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-2066778 https://reactome.org/PathwayBrowser/#/R-DME-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2090037 https://reactome.org/PathwayBrowser/#/R-DME-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2090038 https://reactome.org/PathwayBrowser/#/R-DME-2090038 NAGLU hydrolyses heparan chain(2) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2090043 https://reactome.org/PathwayBrowser/#/R-DME-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2090079 https://reactome.org/PathwayBrowser/#/R-DME-2090079 GLB1 hydrolyses linker chain(2) IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-209055 https://reactome.org/PathwayBrowser/#/R-DME-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15377 R-ALL-351603 H2O [secretory granule lumen] R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2105001 https://reactome.org/PathwayBrowser/#/R-DME-2105001 HEXA cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2161195 https://reactome.org/PathwayBrowser/#/R-DME-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-2162187 https://reactome.org/PathwayBrowser/#/R-DME-2162187 COQ6 hydroxylates DHB IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2162225 https://reactome.org/PathwayBrowser/#/R-DME-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2162226 https://reactome.org/PathwayBrowser/#/R-DME-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-2162227 https://reactome.org/PathwayBrowser/#/R-DME-2162227 GUSB tetramer hydrolyses (HA)2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2187401 https://reactome.org/PathwayBrowser/#/R-DME-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-2393954 https://reactome.org/PathwayBrowser/#/R-DME-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2529015 https://reactome.org/PathwayBrowser/#/R-DME-2529015 Dephosphorylation of CK2-modified condensin I IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-265783 https://reactome.org/PathwayBrowser/#/R-DME-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-266012 https://reactome.org/PathwayBrowser/#/R-DME-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-266046 https://reactome.org/PathwayBrowser/#/R-DME-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-266070 https://reactome.org/PathwayBrowser/#/R-DME-266070 LTC4 is exported from the cytosol by ABCC1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-266072 https://reactome.org/PathwayBrowser/#/R-DME-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-266082 https://reactome.org/PathwayBrowser/#/R-DME-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2730847 https://reactome.org/PathwayBrowser/#/R-DME-2730847 Hydrolysis of PIP2 by PLCG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2730849 https://reactome.org/PathwayBrowser/#/R-DME-2730849 Calcineurin binds and dephosphorylates NFAT IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-2995330 https://reactome.org/PathwayBrowser/#/R-DME-2995330 COX10 transforms heme to heme O IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-2995334 https://reactome.org/PathwayBrowser/#/R-DME-2995334 COX15 transforms heme O to heme A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-2995388 https://reactome.org/PathwayBrowser/#/R-DME-2995388 PP2A dephosphorylates BANF1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-3002811 https://reactome.org/PathwayBrowser/#/R-DME-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3095901 https://reactome.org/PathwayBrowser/#/R-DME-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-3215310 https://reactome.org/PathwayBrowser/#/R-DME-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-3262512 https://reactome.org/PathwayBrowser/#/R-DME-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-3266566 https://reactome.org/PathwayBrowser/#/R-DME-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-3322995 https://reactome.org/PathwayBrowser/#/R-DME-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3341343 https://reactome.org/PathwayBrowser/#/R-DME-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3697882 https://reactome.org/PathwayBrowser/#/R-DME-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-3697894 https://reactome.org/PathwayBrowser/#/R-DME-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-372519 https://reactome.org/PathwayBrowser/#/R-DME-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-3769447 https://reactome.org/PathwayBrowser/#/R-DME-3769447 HDAC1:2-containing complex deacetylate histones IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-377643 https://reactome.org/PathwayBrowser/#/R-DME-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-3777129 https://reactome.org/PathwayBrowser/#/R-DME-3777129 HDAC3 containing complexes deacetylate histone IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3781011 https://reactome.org/PathwayBrowser/#/R-DME-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-3781018 https://reactome.org/PathwayBrowser/#/R-DME-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-3782655 https://reactome.org/PathwayBrowser/#/R-DME-3782655 HDAC10 deacetylates histone IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-380949 https://reactome.org/PathwayBrowser/#/R-DME-380949 AMPK is dephosphorylated IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-382560 https://reactome.org/PathwayBrowser/#/R-DME-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-382575 https://reactome.org/PathwayBrowser/#/R-DME-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-383190 https://reactome.org/PathwayBrowser/#/R-DME-383190 HCO3- transport through ion channel IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-389986 https://reactome.org/PathwayBrowser/#/R-DME-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-390252 https://reactome.org/PathwayBrowser/#/R-DME-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-390329 https://reactome.org/PathwayBrowser/#/R-DME-390329 Dephosphorylation of AKT by PP2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-390393 https://reactome.org/PathwayBrowser/#/R-DME-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-399998 https://reactome.org/PathwayBrowser/#/R-DME-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-4084976 https://reactome.org/PathwayBrowser/#/R-DME-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-4084989 https://reactome.org/PathwayBrowser/#/R-DME-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-4093339 https://reactome.org/PathwayBrowser/#/R-DME-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-418553 https://reactome.org/PathwayBrowser/#/R-DME-418553 cAMP degradation by Phosphodiesterases IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-428205 https://reactome.org/PathwayBrowser/#/R-DME-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-428231 https://reactome.org/PathwayBrowser/#/R-DME-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-428690 https://reactome.org/PathwayBrowser/#/R-DME-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-428696 https://reactome.org/PathwayBrowser/#/R-DME-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-429730 https://reactome.org/PathwayBrowser/#/R-DME-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-429860 https://reactome.org/PathwayBrowser/#/R-DME-429860 DCP1-DCP2 complex decaps mRNA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-429961 https://reactome.org/PathwayBrowser/#/R-DME-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-430028 https://reactome.org/PathwayBrowser/#/R-DME-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-432010 https://reactome.org/PathwayBrowser/#/R-DME-432010 Aquaporin-1 passively transports water into cell IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-432010 https://reactome.org/PathwayBrowser/#/R-DME-432010 Aquaporin-1 passively transports water into cell IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-432054 https://reactome.org/PathwayBrowser/#/R-DME-432054 Aquaporin-1 passively transports water out of cell IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-432054 https://reactome.org/PathwayBrowser/#/R-DME-432054 Aquaporin-1 passively transports water out of cell IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-432065 https://reactome.org/PathwayBrowser/#/R-DME-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-432065 https://reactome.org/PathwayBrowser/#/R-DME-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-432067 https://reactome.org/PathwayBrowser/#/R-DME-432067 Aquaporin-4 passively transports water out of cell IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-432067 https://reactome.org/PathwayBrowser/#/R-DME-432067 Aquaporin-4 passively transports water out of cell IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-4419948 https://reactome.org/PathwayBrowser/#/R-DME-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-449937 https://reactome.org/PathwayBrowser/#/R-DME-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-452036 https://reactome.org/PathwayBrowser/#/R-DME-452036 arginine + H2O => ornithine + urea [ARG2] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-4551451 https://reactome.org/PathwayBrowser/#/R-DME-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-507868 https://reactome.org/PathwayBrowser/#/R-DME-507868 Aquaporins passively transport water into cells IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-507868 https://reactome.org/PathwayBrowser/#/R-DME-507868 Aquaporins passively transport water into cells IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-507870 https://reactome.org/PathwayBrowser/#/R-DME-507870 Aquaporins passively transport water out of cells IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-507870 https://reactome.org/PathwayBrowser/#/R-DME-507870 Aquaporins passively transport water out of cells IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5221130 https://reactome.org/PathwayBrowser/#/R-DME-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5251989 https://reactome.org/PathwayBrowser/#/R-DME-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5362459 https://reactome.org/PathwayBrowser/#/R-DME-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-5433072 https://reactome.org/PathwayBrowser/#/R-DME-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5433074 https://reactome.org/PathwayBrowser/#/R-DME-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-548843 https://reactome.org/PathwayBrowser/#/R-DME-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5607735 https://reactome.org/PathwayBrowser/#/R-DME-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5618093 https://reactome.org/PathwayBrowser/#/R-DME-5618093 ATP hydrolysis by HSP90 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5623513 https://reactome.org/PathwayBrowser/#/R-DME-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5631885 https://reactome.org/PathwayBrowser/#/R-DME-5631885 PRDX1 overoxidizes IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5651828 https://reactome.org/PathwayBrowser/#/R-DME-5651828 PARG dePARylates PARP1,PARP2 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5653786 https://reactome.org/PathwayBrowser/#/R-DME-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5672957 https://reactome.org/PathwayBrowser/#/R-DME-5672957 PP2A dephosphorylates KSR1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5672961 https://reactome.org/PathwayBrowser/#/R-DME-5672961 PP2A dephosphorylates inactive RAFs IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5675376 https://reactome.org/PathwayBrowser/#/R-DME-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5675431 https://reactome.org/PathwayBrowser/#/R-DME-5675431 PP2A dephosphorylates RAF1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5675433 https://reactome.org/PathwayBrowser/#/R-DME-5675433 PP5 dephosphorylates RAF1 S338 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5676637 https://reactome.org/PathwayBrowser/#/R-DME-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5678863 https://reactome.org/PathwayBrowser/#/R-DME-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5679041 https://reactome.org/PathwayBrowser/#/R-DME-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5682285 https://reactome.org/PathwayBrowser/#/R-DME-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5683714 https://reactome.org/PathwayBrowser/#/R-DME-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5683967 https://reactome.org/PathwayBrowser/#/R-DME-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Drosophila melanogaster 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-DME-5684864 https://reactome.org/PathwayBrowser/#/R-DME-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5687464 https://reactome.org/PathwayBrowser/#/R-DME-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5687664 https://reactome.org/PathwayBrowser/#/R-DME-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5687758 https://reactome.org/PathwayBrowser/#/R-DME-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5688797 https://reactome.org/PathwayBrowser/#/R-DME-5688797 ATXN3 family cleave Ub chains IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5689950 https://reactome.org/PathwayBrowser/#/R-DME-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5689973 https://reactome.org/PathwayBrowser/#/R-DME-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690043 https://reactome.org/PathwayBrowser/#/R-DME-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-5690066 https://reactome.org/PathwayBrowser/#/R-DME-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5690080 https://reactome.org/PathwayBrowser/#/R-DME-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690152 https://reactome.org/PathwayBrowser/#/R-DME-5690152 USP5 cleaves polyubiquitin IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5690157 https://reactome.org/PathwayBrowser/#/R-DME-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690159 https://reactome.org/PathwayBrowser/#/R-DME-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690196 https://reactome.org/PathwayBrowser/#/R-DME-5690196 USP8 deubiquitinates RNF128 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690319 https://reactome.org/PathwayBrowser/#/R-DME-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-5690517 https://reactome.org/PathwayBrowser/#/R-DME-5690517 PPT1 hydrolyses palmitoylated proteins IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5690759 https://reactome.org/PathwayBrowser/#/R-DME-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5690790 https://reactome.org/PathwayBrowser/#/R-DME-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690808 https://reactome.org/PathwayBrowser/#/R-DME-5690808 UCHL3, SENP8 cleave NEDD8 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690856 https://reactome.org/PathwayBrowser/#/R-DME-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5690870 https://reactome.org/PathwayBrowser/#/R-DME-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5691381 https://reactome.org/PathwayBrowser/#/R-DME-5691381 MYSM1 deubiquitinates Histone H2A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5692462 https://reactome.org/PathwayBrowser/#/R-DME-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-5693346 https://reactome.org/PathwayBrowser/#/R-DME-5693346 CECRI deaminates Ade-Rib to Ino IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5693373 https://reactome.org/PathwayBrowser/#/R-DME-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-5693724 https://reactome.org/PathwayBrowser/#/R-DME-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Drosophila melanogaster 15377 R-ALL-5693747 H2O [lipid droplet] R-DME-5693751 https://reactome.org/PathwayBrowser/#/R-DME-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-5693807 https://reactome.org/PathwayBrowser/#/R-DME-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5694077 https://reactome.org/PathwayBrowser/#/R-DME-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-5694109 https://reactome.org/PathwayBrowser/#/R-DME-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5694126 https://reactome.org/PathwayBrowser/#/R-DME-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5694485 https://reactome.org/PathwayBrowser/#/R-DME-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5694583 https://reactome.org/PathwayBrowser/#/R-DME-5694583 ABHD4 hydrolyses NAPE IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-5696197 https://reactome.org/PathwayBrowser/#/R-DME-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696230 https://reactome.org/PathwayBrowser/#/R-DME-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696365 https://reactome.org/PathwayBrowser/#/R-DME-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-5696408 https://reactome.org/PathwayBrowser/#/R-DME-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-5696415 https://reactome.org/PathwayBrowser/#/R-DME-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696600 https://reactome.org/PathwayBrowser/#/R-DME-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5696605 https://reactome.org/PathwayBrowser/#/R-DME-5696605 USP12, USP26 deubiquitinate AR IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696627 https://reactome.org/PathwayBrowser/#/R-DME-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696872 https://reactome.org/PathwayBrowser/#/R-DME-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696945 https://reactome.org/PathwayBrowser/#/R-DME-5696945 USP33 deubiquitinates CCP110,ARRB IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-5696968 https://reactome.org/PathwayBrowser/#/R-DME-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-5697009 https://reactome.org/PathwayBrowser/#/R-DME-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6781764 https://reactome.org/PathwayBrowser/#/R-DME-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6781779 https://reactome.org/PathwayBrowser/#/R-DME-6781779 USP13 deubiquitinates BECN1,USP10 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6782069 https://reactome.org/PathwayBrowser/#/R-DME-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6782628 https://reactome.org/PathwayBrowser/#/R-DME-6782628 USP8 deubiquitinates STAM2:HGS IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6782820 https://reactome.org/PathwayBrowser/#/R-DME-6782820 USP17 deubiquitinates SUDS3 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6783177 https://reactome.org/PathwayBrowser/#/R-DME-6783177 USP21 deubiquitinates GATA3,IL33 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6784959 https://reactome.org/PathwayBrowser/#/R-DME-6784959 BPHL hydrolyses VACV to ACV IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-6786421 https://reactome.org/PathwayBrowser/#/R-DME-6786421 CHIA hydrolyses chitin IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-6786652 https://reactome.org/PathwayBrowser/#/R-DME-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6787632 https://reactome.org/PathwayBrowser/#/R-DME-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6788295 https://reactome.org/PathwayBrowser/#/R-DME-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Drosophila melanogaster 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-6792445 https://reactome.org/PathwayBrowser/#/R-DME-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6797627 https://reactome.org/PathwayBrowser/#/R-DME-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-6797913 https://reactome.org/PathwayBrowser/#/R-DME-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-6797955 https://reactome.org/PathwayBrowser/#/R-DME-6797955 ALDH7A1 oxidises BETALD to BET IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-6799581 https://reactome.org/PathwayBrowser/#/R-DME-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6799604 https://reactome.org/PathwayBrowser/#/R-DME-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-6799977 https://reactome.org/PathwayBrowser/#/R-DME-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-6801462 https://reactome.org/PathwayBrowser/#/R-DME-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6803789 https://reactome.org/PathwayBrowser/#/R-DME-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6805650 https://reactome.org/PathwayBrowser/#/R-DME-6805650 MTA2-NuRD complex deacetylates TP53 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6807118 https://reactome.org/PathwayBrowser/#/R-DME-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6807206 https://reactome.org/PathwayBrowser/#/R-DME-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6809320 https://reactome.org/PathwayBrowser/#/R-DME-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6809325 https://reactome.org/PathwayBrowser/#/R-DME-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6809720 https://reactome.org/PathwayBrowser/#/R-DME-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6809777 https://reactome.org/PathwayBrowser/#/R-DME-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6809778 https://reactome.org/PathwayBrowser/#/R-DME-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-6810410 https://reactome.org/PathwayBrowser/#/R-DME-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6810464 https://reactome.org/PathwayBrowser/#/R-DME-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6811504 https://reactome.org/PathwayBrowser/#/R-DME-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6813740 https://reactome.org/PathwayBrowser/#/R-DME-6813740 GDE1 hydrolyzes GroPIns IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-6814254 https://reactome.org/PathwayBrowser/#/R-DME-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-69199 https://reactome.org/PathwayBrowser/#/R-DME-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-70262 https://reactome.org/PathwayBrowser/#/R-DME-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-70479 https://reactome.org/PathwayBrowser/#/R-DME-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-70494 https://reactome.org/PathwayBrowser/#/R-DME-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-70569 https://reactome.org/PathwayBrowser/#/R-DME-70569 arginine + H2O => ornithine + urea [ARG1] IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70609 https://reactome.org/PathwayBrowser/#/R-DME-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70785 https://reactome.org/PathwayBrowser/#/R-DME-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70870 https://reactome.org/PathwayBrowser/#/R-DME-70870 ECHS1 hydrates methacrylyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-70982 https://reactome.org/PathwayBrowser/#/R-DME-70982 FH tetramer hydrates fumarate to L-malate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71146 https://reactome.org/PathwayBrowser/#/R-DME-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71296 https://reactome.org/PathwayBrowser/#/R-DME-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71660 https://reactome.org/PathwayBrowser/#/R-DME-71660 Enolase dimers dehydrates 2PG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-71732 https://reactome.org/PathwayBrowser/#/R-DME-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-71825 https://reactome.org/PathwayBrowser/#/R-DME-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73608 https://reactome.org/PathwayBrowser/#/R-DME-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73797 https://reactome.org/PathwayBrowser/#/R-DME-73797 FAICAR => IMP + H2O IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-73815 https://reactome.org/PathwayBrowser/#/R-DME-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-74248 https://reactome.org/PathwayBrowser/#/R-DME-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-74733 https://reactome.org/PathwayBrowser/#/R-DME-74733 Insulin receptor de-phosphorylation IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-75899 https://reactome.org/PathwayBrowser/#/R-DME-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-76590 https://reactome.org/PathwayBrowser/#/R-DME-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77256 https://reactome.org/PathwayBrowser/#/R-DME-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77277 https://reactome.org/PathwayBrowser/#/R-DME-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77301 https://reactome.org/PathwayBrowser/#/R-DME-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77314 https://reactome.org/PathwayBrowser/#/R-DME-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77325 https://reactome.org/PathwayBrowser/#/R-DME-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77333 https://reactome.org/PathwayBrowser/#/R-DME-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-77344 https://reactome.org/PathwayBrowser/#/R-DME-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-77615 https://reactome.org/PathwayBrowser/#/R-DME-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-870437 https://reactome.org/PathwayBrowser/#/R-DME-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8848215 https://reactome.org/PathwayBrowser/#/R-DME-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8848339 https://reactome.org/PathwayBrowser/#/R-DME-8848339 PNPLA5 hydrolyzes TAG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8848484 https://reactome.org/PathwayBrowser/#/R-DME-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8849969 https://reactome.org/PathwayBrowser/#/R-DME-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8850594 https://reactome.org/PathwayBrowser/#/R-DME-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8853379 https://reactome.org/PathwayBrowser/#/R-DME-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-8853686 https://reactome.org/PathwayBrowser/#/R-DME-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8854173 https://reactome.org/PathwayBrowser/#/R-DME-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8854255 https://reactome.org/PathwayBrowser/#/R-DME-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8854329 https://reactome.org/PathwayBrowser/#/R-DME-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8854604 https://reactome.org/PathwayBrowser/#/R-DME-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8855490 https://reactome.org/PathwayBrowser/#/R-DME-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-8856951 https://reactome.org/PathwayBrowser/#/R-DME-8856951 PP2A demethylation by PPME1 IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8862320 https://reactome.org/PathwayBrowser/#/R-DME-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8864125 https://reactome.org/PathwayBrowser/#/R-DME-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8867047 https://reactome.org/PathwayBrowser/#/R-DME-8867047 PTPN3 dephosphorylates EPS15 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8867658 https://reactome.org/PathwayBrowser/#/R-DME-8867658 PTPN3 dephosphorylates MAPK12 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8868648 https://reactome.org/PathwayBrowser/#/R-DME-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8868658 https://reactome.org/PathwayBrowser/#/R-DME-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8868661 https://reactome.org/PathwayBrowser/#/R-DME-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8869425 https://reactome.org/PathwayBrowser/#/R-DME-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8869506 https://reactome.org/PathwayBrowser/#/R-DME-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8874435 https://reactome.org/PathwayBrowser/#/R-DME-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8878787 https://reactome.org/PathwayBrowser/#/R-DME-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-893596 https://reactome.org/PathwayBrowser/#/R-DME-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8937442 https://reactome.org/PathwayBrowser/#/R-DME-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8940074 https://reactome.org/PathwayBrowser/#/R-DME-8940074 NT5E:Zn2+ hydrolyses NMN IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8943279 https://reactome.org/PathwayBrowser/#/R-DME-8943279 GGT dimers hydrolyse GSH IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-8952069 https://reactome.org/PathwayBrowser/#/R-DME-8952069 HDAC4 deacetylates RUNX3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8952137 https://reactome.org/PathwayBrowser/#/R-DME-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8952251 https://reactome.org/PathwayBrowser/#/R-DME-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Drosophila melanogaster 15377 R-ALL-2022884 H2O [Golgi lumen] R-DME-8953499 https://reactome.org/PathwayBrowser/#/R-DME-8953499 IMPAD1 hydrolyses PAP to AMP IEA Drosophila melanogaster 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DME-8954398 https://reactome.org/PathwayBrowser/#/R-DME-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8955794 https://reactome.org/PathwayBrowser/#/R-DME-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-8955817 https://reactome.org/PathwayBrowser/#/R-DME-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-8957389 https://reactome.org/PathwayBrowser/#/R-DME-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-8980228 https://reactome.org/PathwayBrowser/#/R-DME-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8981637 https://reactome.org/PathwayBrowser/#/R-DME-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-8986083 https://reactome.org/PathwayBrowser/#/R-DME-8986083 USP33 deubiquitinates ROBO1 IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-9008822 https://reactome.org/PathwayBrowser/#/R-DME-9008822 PPM1D dephosphorylates RUNX2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9013022 https://reactome.org/PathwayBrowser/#/R-DME-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9013144 https://reactome.org/PathwayBrowser/#/R-DME-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9013161 https://reactome.org/PathwayBrowser/#/R-DME-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9013437 https://reactome.org/PathwayBrowser/#/R-DME-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9014295 https://reactome.org/PathwayBrowser/#/R-DME-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9014434 https://reactome.org/PathwayBrowser/#/R-DME-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9014641 https://reactome.org/PathwayBrowser/#/R-DME-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9017488 https://reactome.org/PathwayBrowser/#/R-DME-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018745 https://reactome.org/PathwayBrowser/#/R-DME-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018806 https://reactome.org/PathwayBrowser/#/R-DME-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018814 https://reactome.org/PathwayBrowser/#/R-DME-9018814 RHOT1 hydrolyzes GTP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018826 https://reactome.org/PathwayBrowser/#/R-DME-9018826 RHOT2 hydrolyzes GTP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018862 https://reactome.org/PathwayBrowser/#/R-DME-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9018877 https://reactome.org/PathwayBrowser/#/R-DME-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9020252 https://reactome.org/PathwayBrowser/#/R-DME-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9020253 https://reactome.org/PathwayBrowser/#/R-DME-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9020257 https://reactome.org/PathwayBrowser/#/R-DME-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9020258 https://reactome.org/PathwayBrowser/#/R-DME-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9020270 https://reactome.org/PathwayBrowser/#/R-DME-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9024890 https://reactome.org/PathwayBrowser/#/R-DME-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9033491 https://reactome.org/PathwayBrowser/#/R-DME-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Drosophila melanogaster 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DME-9033520 https://reactome.org/PathwayBrowser/#/R-DME-9033520 TYSND1 cleaves TYSND1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-936883 https://reactome.org/PathwayBrowser/#/R-DME-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-936895 https://reactome.org/PathwayBrowser/#/R-DME-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-939763 https://reactome.org/PathwayBrowser/#/R-DME-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-947531 https://reactome.org/PathwayBrowser/#/R-DME-947531 Molybdenum ion transfer onto molybdopterin IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-947535 https://reactome.org/PathwayBrowser/#/R-DME-947535 Cyclisation of GTP to precursor Z IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-947591 https://reactome.org/PathwayBrowser/#/R-DME-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9624893 https://reactome.org/PathwayBrowser/#/R-DME-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9635739 https://reactome.org/PathwayBrowser/#/R-DME-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-9638075 https://reactome.org/PathwayBrowser/#/R-DME-9638075 HEXB cleaves the terminal GalNAc from DS IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-9638076 https://reactome.org/PathwayBrowser/#/R-DME-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Drosophila melanogaster 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DME-9638078 https://reactome.org/PathwayBrowser/#/R-DME-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9644869 https://reactome.org/PathwayBrowser/#/R-DME-9644869 p-S54-PDE4B hydrolyses cAMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9647994 https://reactome.org/PathwayBrowser/#/R-DME-9647994 RAS proteins are depalmitoylated IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9653514 https://reactome.org/PathwayBrowser/#/R-DME-9653514 USP17L2 deubiquitinates RCE1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9661417 https://reactome.org/PathwayBrowser/#/R-DME-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9667952 https://reactome.org/PathwayBrowser/#/R-DME-9667952 ANKLE2 is deacetylated by SIRT2 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9674127 https://reactome.org/PathwayBrowser/#/R-DME-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9693282 https://reactome.org/PathwayBrowser/#/R-DME-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-9701565 https://reactome.org/PathwayBrowser/#/R-DME-9701565 HDACs deacetylate p-STAT3 dimers IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9706399 https://reactome.org/PathwayBrowser/#/R-DME-9706399 RHOBTB3 hydrolyzes ATP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9708261 https://reactome.org/PathwayBrowser/#/R-DME-9708261 PDE4A hydrolyses cAMP to AMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9727567 https://reactome.org/PathwayBrowser/#/R-DME-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9750546 https://reactome.org/PathwayBrowser/#/R-DME-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9750656 https://reactome.org/PathwayBrowser/#/R-DME-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753278 https://reactome.org/PathwayBrowser/#/R-DME-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753280 https://reactome.org/PathwayBrowser/#/R-DME-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753283 https://reactome.org/PathwayBrowser/#/R-DME-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753284 https://reactome.org/PathwayBrowser/#/R-DME-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753632 https://reactome.org/PathwayBrowser/#/R-DME-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753634 https://reactome.org/PathwayBrowser/#/R-DME-9753634 GGT dimers hydrolyse APAP-SG IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9753944 https://reactome.org/PathwayBrowser/#/R-DME-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9755030 https://reactome.org/PathwayBrowser/#/R-DME-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9755078 https://reactome.org/PathwayBrowser/#/R-DME-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DME-975594 https://reactome.org/PathwayBrowser/#/R-DME-975594 PLB1 hydrolyses RPALM to atROL IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-977324 https://reactome.org/PathwayBrowser/#/R-DME-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9794120 https://reactome.org/PathwayBrowser/#/R-DME-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9794572 https://reactome.org/PathwayBrowser/#/R-DME-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-9825772 https://reactome.org/PathwayBrowser/#/R-DME-9825772 SIRT1 deacetylates HINT1 dimer IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9838004 https://reactome.org/PathwayBrowser/#/R-DME-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9838081 https://reactome.org/PathwayBrowser/#/R-DME-9838081 LONP1 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9838289 https://reactome.org/PathwayBrowser/#/R-DME-9838289 CLPXP degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9839059 https://reactome.org/PathwayBrowser/#/R-DME-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Drosophila melanogaster 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DME-9839072 https://reactome.org/PathwayBrowser/#/R-DME-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9839105 https://reactome.org/PathwayBrowser/#/R-DME-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Drosophila melanogaster 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DME-9839110 https://reactome.org/PathwayBrowser/#/R-DME-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9839113 https://reactome.org/PathwayBrowser/#/R-DME-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9853385 https://reactome.org/PathwayBrowser/#/R-DME-9853385 PPP1CC dephosphorylates PLK1 IEA Drosophila melanogaster 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DME-9861626 https://reactome.org/PathwayBrowser/#/R-DME-9861626 SIRT4 cleaves lipoyl from DLAT IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9861725 https://reactome.org/PathwayBrowser/#/R-DME-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9865167 https://reactome.org/PathwayBrowser/#/R-DME-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9912636 https://reactome.org/PathwayBrowser/#/R-DME-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9912655 https://reactome.org/PathwayBrowser/#/R-DME-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9912747 https://reactome.org/PathwayBrowser/#/R-DME-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9912751 https://reactome.org/PathwayBrowser/#/R-DME-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9915971 https://reactome.org/PathwayBrowser/#/R-DME-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Drosophila melanogaster 15377 R-ALL-29356 H2O [cytosol] R-DME-9915997 https://reactome.org/PathwayBrowser/#/R-DME-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Drosophila melanogaster 15377 R-ALL-113518 H2O [nucleoplasm] R-DME-997326 https://reactome.org/PathwayBrowser/#/R-DME-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Drosophila melanogaster 15377 R-ALL-109276 H2O [extracellular region] R-DRE-109278 https://reactome.org/PathwayBrowser/#/R-DRE-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-109291 https://reactome.org/PathwayBrowser/#/R-DRE-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-109380 https://reactome.org/PathwayBrowser/#/R-DRE-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-109387 https://reactome.org/PathwayBrowser/#/R-DRE-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-109415 https://reactome.org/PathwayBrowser/#/R-DRE-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-109449 https://reactome.org/PathwayBrowser/#/R-DRE-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-111742 https://reactome.org/PathwayBrowser/#/R-DRE-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-111751 https://reactome.org/PathwayBrowser/#/R-DRE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-111804 https://reactome.org/PathwayBrowser/#/R-DRE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-113503 https://reactome.org/PathwayBrowser/#/R-DRE-113503 PP2A mediated localization of RB1 protein in chromatin IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1169192 https://reactome.org/PathwayBrowser/#/R-DRE-1169192 PTP1B dephosphorylates GHR IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1237129 https://reactome.org/PathwayBrowser/#/R-DRE-1237129 Acireductone is created IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1247910 https://reactome.org/PathwayBrowser/#/R-DRE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1247935 https://reactome.org/PathwayBrowser/#/R-DRE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-1363274 https://reactome.org/PathwayBrowser/#/R-DRE-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-140359 https://reactome.org/PathwayBrowser/#/R-DRE-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1454916 https://reactome.org/PathwayBrowser/#/R-DRE-1454916 The ABCC family mediates organic anion transport IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1454928 https://reactome.org/PathwayBrowser/#/R-DRE-1454928 ABCG4 may mediate cholesterol efflux IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482543 https://reactome.org/PathwayBrowser/#/R-DRE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482545 https://reactome.org/PathwayBrowser/#/R-DRE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482571 https://reactome.org/PathwayBrowser/#/R-DRE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482604 https://reactome.org/PathwayBrowser/#/R-DRE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482612 https://reactome.org/PathwayBrowser/#/R-DRE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482629 https://reactome.org/PathwayBrowser/#/R-DRE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482656 https://reactome.org/PathwayBrowser/#/R-DRE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482685 https://reactome.org/PathwayBrowser/#/R-DRE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482696 https://reactome.org/PathwayBrowser/#/R-DRE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-1482759 https://reactome.org/PathwayBrowser/#/R-DRE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482771 https://reactome.org/PathwayBrowser/#/R-DRE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482777 https://reactome.org/PathwayBrowser/#/R-DRE-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482811 https://reactome.org/PathwayBrowser/#/R-DRE-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482816 https://reactome.org/PathwayBrowser/#/R-DRE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482825 https://reactome.org/PathwayBrowser/#/R-DRE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482827 https://reactome.org/PathwayBrowser/#/R-DRE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482828 https://reactome.org/PathwayBrowser/#/R-DRE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482856 https://reactome.org/PathwayBrowser/#/R-DRE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482862 https://reactome.org/PathwayBrowser/#/R-DRE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482868 https://reactome.org/PathwayBrowser/#/R-DRE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482884 https://reactome.org/PathwayBrowser/#/R-DRE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482892 https://reactome.org/PathwayBrowser/#/R-DRE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482897 https://reactome.org/PathwayBrowser/#/R-DRE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1482900 https://reactome.org/PathwayBrowser/#/R-DRE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1483096 https://reactome.org/PathwayBrowser/#/R-DRE-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1483159 https://reactome.org/PathwayBrowser/#/R-DRE-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1483203 https://reactome.org/PathwayBrowser/#/R-DRE-1483203 PA is dephosphorylated to DAG by LPIN IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-159425 https://reactome.org/PathwayBrowser/#/R-DRE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602368 https://reactome.org/PathwayBrowser/#/R-DRE-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602374 https://reactome.org/PathwayBrowser/#/R-DRE-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602377 https://reactome.org/PathwayBrowser/#/R-DRE-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602398 https://reactome.org/PathwayBrowser/#/R-DRE-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602417 https://reactome.org/PathwayBrowser/#/R-DRE-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-1602446 https://reactome.org/PathwayBrowser/#/R-DRE-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1605723 https://reactome.org/PathwayBrowser/#/R-DRE-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1605768 https://reactome.org/PathwayBrowser/#/R-DRE-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1606583 https://reactome.org/PathwayBrowser/#/R-DRE-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1614524 https://reactome.org/PathwayBrowser/#/R-DRE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1614583 https://reactome.org/PathwayBrowser/#/R-DRE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to pyruvate and H2S IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-1638032 https://reactome.org/PathwayBrowser/#/R-DRE-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-164832 https://reactome.org/PathwayBrowser/#/R-DRE-164832 ATPase synthesizes ATP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-1667005 https://reactome.org/PathwayBrowser/#/R-DRE-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1675795 https://reactome.org/PathwayBrowser/#/R-DRE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1675949 https://reactome.org/PathwayBrowser/#/R-DRE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1675994 https://reactome.org/PathwayBrowser/#/R-DRE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676065 https://reactome.org/PathwayBrowser/#/R-DRE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676105 https://reactome.org/PathwayBrowser/#/R-DRE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676114 https://reactome.org/PathwayBrowser/#/R-DRE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676124 https://reactome.org/PathwayBrowser/#/R-DRE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676141 https://reactome.org/PathwayBrowser/#/R-DRE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676149 https://reactome.org/PathwayBrowser/#/R-DRE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676162 https://reactome.org/PathwayBrowser/#/R-DRE-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676164 https://reactome.org/PathwayBrowser/#/R-DRE-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676203 https://reactome.org/PathwayBrowser/#/R-DRE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1676204 https://reactome.org/PathwayBrowser/#/R-DRE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-1678650 https://reactome.org/PathwayBrowser/#/R-DRE-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-173739 https://reactome.org/PathwayBrowser/#/R-DRE-173739 Spontaneous hydrolysis of C3 thioester IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-174124 https://reactome.org/PathwayBrowser/#/R-DRE-174124 Dephosphorylation of phospho-Cdh1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-174391 https://reactome.org/PathwayBrowser/#/R-DRE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-174401 https://reactome.org/PathwayBrowser/#/R-DRE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-1793182 https://reactome.org/PathwayBrowser/#/R-DRE-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-1793209 https://reactome.org/PathwayBrowser/#/R-DRE-1793209 HYAL1 hydrolyses Chondroitin chains IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855154 https://reactome.org/PathwayBrowser/#/R-DRE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855159 https://reactome.org/PathwayBrowser/#/R-DRE-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-1855163 https://reactome.org/PathwayBrowser/#/R-DRE-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855165 https://reactome.org/PathwayBrowser/#/R-DRE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855166 https://reactome.org/PathwayBrowser/#/R-DRE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855171 https://reactome.org/PathwayBrowser/#/R-DRE-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855180 https://reactome.org/PathwayBrowser/#/R-DRE-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855198 https://reactome.org/PathwayBrowser/#/R-DRE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-1855200 https://reactome.org/PathwayBrowser/#/R-DRE-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855202 https://reactome.org/PathwayBrowser/#/R-DRE-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855205 https://reactome.org/PathwayBrowser/#/R-DRE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855210 https://reactome.org/PathwayBrowser/#/R-DRE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855211 https://reactome.org/PathwayBrowser/#/R-DRE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855218 https://reactome.org/PathwayBrowser/#/R-DRE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855219 https://reactome.org/PathwayBrowser/#/R-DRE-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855221 https://reactome.org/PathwayBrowser/#/R-DRE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1855222 https://reactome.org/PathwayBrowser/#/R-DRE-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-1855225 https://reactome.org/PathwayBrowser/#/R-DRE-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1861788 https://reactome.org/PathwayBrowser/#/R-DRE-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-1861789 https://reactome.org/PathwayBrowser/#/R-DRE-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-188979 https://reactome.org/PathwayBrowser/#/R-DRE-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-189488 https://reactome.org/PathwayBrowser/#/R-DRE-189488 UROS transforms HMB to URO3 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-191114 https://reactome.org/PathwayBrowser/#/R-DRE-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-192417 https://reactome.org/PathwayBrowser/#/R-DRE-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-192425 https://reactome.org/PathwayBrowser/#/R-DRE-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-192430 https://reactome.org/PathwayBrowser/#/R-DRE-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-193385 https://reactome.org/PathwayBrowser/#/R-DRE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193711 https://reactome.org/PathwayBrowser/#/R-DRE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193766 https://reactome.org/PathwayBrowser/#/R-DRE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-196950 https://reactome.org/PathwayBrowser/#/R-DRE-196950 2xTRAP hydrolyzes FMN to RIB IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-197186 https://reactome.org/PathwayBrowser/#/R-DRE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-199456 https://reactome.org/PathwayBrowser/#/R-DRE-199456 PTEN dephosphorylates PIP3 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-199959 https://reactome.org/PathwayBrowser/#/R-DRE-199959 ERKs are inactivated by protein phosphatase 2A IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-200661 https://reactome.org/PathwayBrowser/#/R-DRE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-200740 https://reactome.org/PathwayBrowser/#/R-DRE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-201035 https://reactome.org/PathwayBrowser/#/R-DRE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-2022381 https://reactome.org/PathwayBrowser/#/R-DRE-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-2022412 https://reactome.org/PathwayBrowser/#/R-DRE-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Danio rerio 15377 R-ALL-2022884 H2O [Golgi lumen] R-DRE-2022887 https://reactome.org/PathwayBrowser/#/R-DRE-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2023971 https://reactome.org/PathwayBrowser/#/R-DRE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2023973 https://reactome.org/PathwayBrowser/#/R-DRE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-202407 https://reactome.org/PathwayBrowser/#/R-DRE-202407 PLC-gamma1 hydrolyses PIP2 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-2028294 https://reactome.org/PathwayBrowser/#/R-DRE-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-203797 https://reactome.org/PathwayBrowser/#/R-DRE-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046083 https://reactome.org/PathwayBrowser/#/R-DRE-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046088 https://reactome.org/PathwayBrowser/#/R-DRE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046090 https://reactome.org/PathwayBrowser/#/R-DRE-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046094 https://reactome.org/PathwayBrowser/#/R-DRE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046095 https://reactome.org/PathwayBrowser/#/R-DRE-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2046100 https://reactome.org/PathwayBrowser/#/R-DRE-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-2066779 https://reactome.org/PathwayBrowser/#/R-DRE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15377 R-ALL-351603 H2O [secretory granule lumen] R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-2160874 https://reactome.org/PathwayBrowser/#/R-DRE-2160874 HYAL1 hydrolyses (HA)50 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161195 https://reactome.org/PathwayBrowser/#/R-DRE-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2161961 https://reactome.org/PathwayBrowser/#/R-DRE-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-2162187 https://reactome.org/PathwayBrowser/#/R-DRE-2162187 COQ6 hydroxylates DHB IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-216723 https://reactome.org/PathwayBrowser/#/R-DRE-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-216757 https://reactome.org/PathwayBrowser/#/R-DRE-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-2309773 https://reactome.org/PathwayBrowser/#/R-DRE-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2393939 https://reactome.org/PathwayBrowser/#/R-DRE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2408551 https://reactome.org/PathwayBrowser/#/R-DRE-2408551 SeMet is converted to AdoSeMet by MAT IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2454118 https://reactome.org/PathwayBrowser/#/R-DRE-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2465924 https://reactome.org/PathwayBrowser/#/R-DRE-2465924 OPN1LW binds 11cRAL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2466085 https://reactome.org/PathwayBrowser/#/R-DRE-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2632521 https://reactome.org/PathwayBrowser/#/R-DRE-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-266072 https://reactome.org/PathwayBrowser/#/R-DRE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-266082 https://reactome.org/PathwayBrowser/#/R-DRE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-2995388 https://reactome.org/PathwayBrowser/#/R-DRE-2995388 PP2A dephosphorylates BANF1 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-3002811 https://reactome.org/PathwayBrowser/#/R-DRE-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-3262512 https://reactome.org/PathwayBrowser/#/R-DRE-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-3322995 https://reactome.org/PathwayBrowser/#/R-DRE-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-3341296 https://reactome.org/PathwayBrowser/#/R-DRE-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-3341343 https://reactome.org/PathwayBrowser/#/R-DRE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-3343700 https://reactome.org/PathwayBrowser/#/R-DRE-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-350604 https://reactome.org/PathwayBrowser/#/R-DRE-350604 Agmatine + H2O <=> putrescine + urea IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-3697882 https://reactome.org/PathwayBrowser/#/R-DRE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-3697894 https://reactome.org/PathwayBrowser/#/R-DRE-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-372519 https://reactome.org/PathwayBrowser/#/R-DRE-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-3781018 https://reactome.org/PathwayBrowser/#/R-DRE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-3782637 https://reactome.org/PathwayBrowser/#/R-DRE-3782637 HDAC8 deacetylates histones IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-3782655 https://reactome.org/PathwayBrowser/#/R-DRE-3782655 HDAC10 deacetylates histone IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-382560 https://reactome.org/PathwayBrowser/#/R-DRE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-382575 https://reactome.org/PathwayBrowser/#/R-DRE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-383190 https://reactome.org/PathwayBrowser/#/R-DRE-383190 HCO3- transport through ion channel IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4084976 https://reactome.org/PathwayBrowser/#/R-DRE-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4084989 https://reactome.org/PathwayBrowser/#/R-DRE-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4084994 https://reactome.org/PathwayBrowser/#/R-DRE-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4085021 https://reactome.org/PathwayBrowser/#/R-DRE-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4085029 https://reactome.org/PathwayBrowser/#/R-DRE-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-4088141 https://reactome.org/PathwayBrowser/#/R-DRE-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-4093339 https://reactome.org/PathwayBrowser/#/R-DRE-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-416559 https://reactome.org/PathwayBrowser/#/R-DRE-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-418553 https://reactome.org/PathwayBrowser/#/R-DRE-418553 cAMP degradation by Phosphodiesterases IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-428231 https://reactome.org/PathwayBrowser/#/R-DRE-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-428696 https://reactome.org/PathwayBrowser/#/R-DRE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-429730 https://reactome.org/PathwayBrowser/#/R-DRE-429730 PPM1L dephosphorylates multiphospho-CERT1-2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-429860 https://reactome.org/PathwayBrowser/#/R-DRE-429860 DCP1-DCP2 complex decaps mRNA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-432010 https://reactome.org/PathwayBrowser/#/R-DRE-432010 Aquaporin-1 passively transports water into cell IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-432010 https://reactome.org/PathwayBrowser/#/R-DRE-432010 Aquaporin-1 passively transports water into cell IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-432054 https://reactome.org/PathwayBrowser/#/R-DRE-432054 Aquaporin-1 passively transports water out of cell IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-432054 https://reactome.org/PathwayBrowser/#/R-DRE-432054 Aquaporin-1 passively transports water out of cell IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-432065 https://reactome.org/PathwayBrowser/#/R-DRE-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-432065 https://reactome.org/PathwayBrowser/#/R-DRE-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-445714 https://reactome.org/PathwayBrowser/#/R-DRE-445714 Aquaporin-3 passively transports water out of cell IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-445714 https://reactome.org/PathwayBrowser/#/R-DRE-445714 Aquaporin-3 passively transports water out of cell IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-449937 https://reactome.org/PathwayBrowser/#/R-DRE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-452036 https://reactome.org/PathwayBrowser/#/R-DRE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-507868 https://reactome.org/PathwayBrowser/#/R-DRE-507868 Aquaporins passively transport water into cells IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-507868 https://reactome.org/PathwayBrowser/#/R-DRE-507868 Aquaporins passively transport water into cells IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-507870 https://reactome.org/PathwayBrowser/#/R-DRE-507870 Aquaporins passively transport water out of cells IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-507870 https://reactome.org/PathwayBrowser/#/R-DRE-507870 Aquaporins passively transport water out of cells IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5223317 https://reactome.org/PathwayBrowser/#/R-DRE-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5251955 https://reactome.org/PathwayBrowser/#/R-DRE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5251959 https://reactome.org/PathwayBrowser/#/R-DRE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5362459 https://reactome.org/PathwayBrowser/#/R-DRE-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-548843 https://reactome.org/PathwayBrowser/#/R-DRE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5603114 https://reactome.org/PathwayBrowser/#/R-DRE-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5623513 https://reactome.org/PathwayBrowser/#/R-DRE-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5628905 https://reactome.org/PathwayBrowser/#/R-DRE-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5631885 https://reactome.org/PathwayBrowser/#/R-DRE-5631885 PRDX1 overoxidizes IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5649705 https://reactome.org/PathwayBrowser/#/R-DRE-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5665809 https://reactome.org/PathwayBrowser/#/R-DRE-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5675373 https://reactome.org/PathwayBrowser/#/R-DRE-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5675376 https://reactome.org/PathwayBrowser/#/R-DRE-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5676637 https://reactome.org/PathwayBrowser/#/R-DRE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5678863 https://reactome.org/PathwayBrowser/#/R-DRE-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5679041 https://reactome.org/PathwayBrowser/#/R-DRE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5687758 https://reactome.org/PathwayBrowser/#/R-DRE-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5688797 https://reactome.org/PathwayBrowser/#/R-DRE-5688797 ATXN3 family cleave Ub chains IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5689973 https://reactome.org/PathwayBrowser/#/R-DRE-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5690066 https://reactome.org/PathwayBrowser/#/R-DRE-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5690080 https://reactome.org/PathwayBrowser/#/R-DRE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5690152 https://reactome.org/PathwayBrowser/#/R-DRE-5690152 USP5 cleaves polyubiquitin IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5690157 https://reactome.org/PathwayBrowser/#/R-DRE-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5690319 https://reactome.org/PathwayBrowser/#/R-DRE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-5690517 https://reactome.org/PathwayBrowser/#/R-DRE-5690517 PPT1 hydrolyses palmitoylated proteins IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5690808 https://reactome.org/PathwayBrowser/#/R-DRE-5690808 UCHL3, SENP8 cleave NEDD8 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5690870 https://reactome.org/PathwayBrowser/#/R-DRE-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5691381 https://reactome.org/PathwayBrowser/#/R-DRE-5691381 MYSM1 deubiquitinates Histone H2A IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5691507 https://reactome.org/PathwayBrowser/#/R-DRE-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5692480 https://reactome.org/PathwayBrowser/#/R-DRE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5692754 https://reactome.org/PathwayBrowser/#/R-DRE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-5693346 https://reactome.org/PathwayBrowser/#/R-DRE-5693346 CECRI deaminates Ade-Rib to Ino IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-5693724 https://reactome.org/PathwayBrowser/#/R-DRE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Danio rerio 15377 R-ALL-5693747 H2O [lipid droplet] R-DRE-5693751 https://reactome.org/PathwayBrowser/#/R-DRE-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5693783 https://reactome.org/PathwayBrowser/#/R-DRE-5693783 NAALADases hydrolyse NAAG IEA Danio rerio 15377 R-ALL-1605715 H2O [lysosomal lumen] R-DRE-5693807 https://reactome.org/PathwayBrowser/#/R-DRE-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-5694109 https://reactome.org/PathwayBrowser/#/R-DRE-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5694137 https://reactome.org/PathwayBrowser/#/R-DRE-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5694485 https://reactome.org/PathwayBrowser/#/R-DRE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5695964 https://reactome.org/PathwayBrowser/#/R-DRE-5695964 ABHD14B hydrolyses PNPB IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696049 https://reactome.org/PathwayBrowser/#/R-DRE-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5696197 https://reactome.org/PathwayBrowser/#/R-DRE-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696230 https://reactome.org/PathwayBrowser/#/R-DRE-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696365 https://reactome.org/PathwayBrowser/#/R-DRE-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5696408 https://reactome.org/PathwayBrowser/#/R-DRE-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-5696415 https://reactome.org/PathwayBrowser/#/R-DRE-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5696465 https://reactome.org/PathwayBrowser/#/R-DRE-5696465 USP45 deubiquitinates ERCC1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696600 https://reactome.org/PathwayBrowser/#/R-DRE-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5696605 https://reactome.org/PathwayBrowser/#/R-DRE-5696605 USP12, USP26 deubiquitinate AR IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696627 https://reactome.org/PathwayBrowser/#/R-DRE-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696872 https://reactome.org/PathwayBrowser/#/R-DRE-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5696958 https://reactome.org/PathwayBrowser/#/R-DRE-5696958 USP44 deubiquitinates CDC20 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5696960 https://reactome.org/PathwayBrowser/#/R-DRE-5696960 USP49 deubiquitinates H2B IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-5696968 https://reactome.org/PathwayBrowser/#/R-DRE-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-5697009 https://reactome.org/PathwayBrowser/#/R-DRE-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6781764 https://reactome.org/PathwayBrowser/#/R-DRE-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6781779 https://reactome.org/PathwayBrowser/#/R-DRE-6781779 USP13 deubiquitinates BECN1,USP10 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-6782069 https://reactome.org/PathwayBrowser/#/R-DRE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-6782820 https://reactome.org/PathwayBrowser/#/R-DRE-6782820 USP17 deubiquitinates SUDS3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-6784402 https://reactome.org/PathwayBrowser/#/R-DRE-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6786190 https://reactome.org/PathwayBrowser/#/R-DRE-6786190 CMBL hydrolyses OM to OLMS IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6786652 https://reactome.org/PathwayBrowser/#/R-DRE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6788295 https://reactome.org/PathwayBrowser/#/R-DRE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6788912 https://reactome.org/PathwayBrowser/#/R-DRE-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6789310 https://reactome.org/PathwayBrowser/#/R-DRE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6792445 https://reactome.org/PathwayBrowser/#/R-DRE-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-6797913 https://reactome.org/PathwayBrowser/#/R-DRE-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-6797955 https://reactome.org/PathwayBrowser/#/R-DRE-6797955 ALDH7A1 oxidises BETALD to BET IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6799604 https://reactome.org/PathwayBrowser/#/R-DRE-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6799695 https://reactome.org/PathwayBrowser/#/R-DRE-6799695 GPX5,6 reduce H2O2 to H2O IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6799977 https://reactome.org/PathwayBrowser/#/R-DRE-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6800198 https://reactome.org/PathwayBrowser/#/R-DRE-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-6801462 https://reactome.org/PathwayBrowser/#/R-DRE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6803545 https://reactome.org/PathwayBrowser/#/R-DRE-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6803789 https://reactome.org/PathwayBrowser/#/R-DRE-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6807206 https://reactome.org/PathwayBrowser/#/R-DRE-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-6809263 https://reactome.org/PathwayBrowser/#/R-DRE-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6809320 https://reactome.org/PathwayBrowser/#/R-DRE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6809325 https://reactome.org/PathwayBrowser/#/R-DRE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6809720 https://reactome.org/PathwayBrowser/#/R-DRE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-6810410 https://reactome.org/PathwayBrowser/#/R-DRE-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6810464 https://reactome.org/PathwayBrowser/#/R-DRE-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6811504 https://reactome.org/PathwayBrowser/#/R-DRE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6813720 https://reactome.org/PathwayBrowser/#/R-DRE-6813720 NCEH1 hydrolyzes cholesterol esters IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-6813740 https://reactome.org/PathwayBrowser/#/R-DRE-6813740 GDE1 hydrolyzes GroPIns IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-6814797 https://reactome.org/PathwayBrowser/#/R-DRE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-70479 https://reactome.org/PathwayBrowser/#/R-DRE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-70494 https://reactome.org/PathwayBrowser/#/R-DRE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70609 https://reactome.org/PathwayBrowser/#/R-DRE-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-70903 https://reactome.org/PathwayBrowser/#/R-DRE-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-70906 https://reactome.org/PathwayBrowser/#/R-DRE-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-70982 https://reactome.org/PathwayBrowser/#/R-DRE-70982 FH tetramer hydrates fumarate to L-malate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-71146 https://reactome.org/PathwayBrowser/#/R-DRE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-71660 https://reactome.org/PathwayBrowser/#/R-DRE-71660 Enolase dimers dehydrates 2PG IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-71732 https://reactome.org/PathwayBrowser/#/R-DRE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73608 https://reactome.org/PathwayBrowser/#/R-DRE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73797 https://reactome.org/PathwayBrowser/#/R-DRE-73797 FAICAR => IMP + H2O IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-73815 https://reactome.org/PathwayBrowser/#/R-DRE-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-74241 https://reactome.org/PathwayBrowser/#/R-DRE-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-76590 https://reactome.org/PathwayBrowser/#/R-DRE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-77277 https://reactome.org/PathwayBrowser/#/R-DRE-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-77301 https://reactome.org/PathwayBrowser/#/R-DRE-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8848215 https://reactome.org/PathwayBrowser/#/R-DRE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8848339 https://reactome.org/PathwayBrowser/#/R-DRE-8848339 PNPLA5 hydrolyzes TAG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8848484 https://reactome.org/PathwayBrowser/#/R-DRE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8849969 https://reactome.org/PathwayBrowser/#/R-DRE-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8850594 https://reactome.org/PathwayBrowser/#/R-DRE-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8853379 https://reactome.org/PathwayBrowser/#/R-DRE-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8854173 https://reactome.org/PathwayBrowser/#/R-DRE-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8854255 https://reactome.org/PathwayBrowser/#/R-DRE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8854329 https://reactome.org/PathwayBrowser/#/R-DRE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8854604 https://reactome.org/PathwayBrowser/#/R-DRE-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8854612 https://reactome.org/PathwayBrowser/#/R-DRE-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-8856951 https://reactome.org/PathwayBrowser/#/R-DRE-8856951 PP2A demethylation by PPME1 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8862320 https://reactome.org/PathwayBrowser/#/R-DRE-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8863804 https://reactome.org/PathwayBrowser/#/R-DRE-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8864036 https://reactome.org/PathwayBrowser/#/R-DRE-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8864125 https://reactome.org/PathwayBrowser/#/R-DRE-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8866405 https://reactome.org/PathwayBrowser/#/R-DRE-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-8867344 https://reactome.org/PathwayBrowser/#/R-DRE-8867344 OMA1 hydrolyses OPA1 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8869425 https://reactome.org/PathwayBrowser/#/R-DRE-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8869506 https://reactome.org/PathwayBrowser/#/R-DRE-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8874435 https://reactome.org/PathwayBrowser/#/R-DRE-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Danio rerio 15377 R-ALL-5668574 H2O [melanosome lumen] R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-8878654 https://reactome.org/PathwayBrowser/#/R-DRE-8878654 ACP6 hydrolyses MYS-LPA IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8878787 https://reactome.org/PathwayBrowser/#/R-DRE-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8932633 https://reactome.org/PathwayBrowser/#/R-DRE-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8933328 https://reactome.org/PathwayBrowser/#/R-DRE-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-893596 https://reactome.org/PathwayBrowser/#/R-DRE-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8937442 https://reactome.org/PathwayBrowser/#/R-DRE-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8940074 https://reactome.org/PathwayBrowser/#/R-DRE-8940074 NT5E:Zn2+ hydrolyses NMN IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8952137 https://reactome.org/PathwayBrowser/#/R-DRE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-8952903 https://reactome.org/PathwayBrowser/#/R-DRE-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8953339 https://reactome.org/PathwayBrowser/#/R-DRE-8953339 DNPH1 hydrolyses dGMP IEA Danio rerio 15377 R-ALL-2022884 H2O [Golgi lumen] R-DRE-8953499 https://reactome.org/PathwayBrowser/#/R-DRE-8953499 IMPAD1 hydrolyses PAP to AMP IEA Danio rerio 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DRE-8954398 https://reactome.org/PathwayBrowser/#/R-DRE-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8955794 https://reactome.org/PathwayBrowser/#/R-DRE-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-8980228 https://reactome.org/PathwayBrowser/#/R-DRE-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-8981637 https://reactome.org/PathwayBrowser/#/R-DRE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9013144 https://reactome.org/PathwayBrowser/#/R-DRE-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9013161 https://reactome.org/PathwayBrowser/#/R-DRE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9013437 https://reactome.org/PathwayBrowser/#/R-DRE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9014295 https://reactome.org/PathwayBrowser/#/R-DRE-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9014434 https://reactome.org/PathwayBrowser/#/R-DRE-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9014641 https://reactome.org/PathwayBrowser/#/R-DRE-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018745 https://reactome.org/PathwayBrowser/#/R-DRE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018806 https://reactome.org/PathwayBrowser/#/R-DRE-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018814 https://reactome.org/PathwayBrowser/#/R-DRE-9018814 RHOT1 hydrolyzes GTP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018826 https://reactome.org/PathwayBrowser/#/R-DRE-9018826 RHOT2 hydrolyzes GTP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018862 https://reactome.org/PathwayBrowser/#/R-DRE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9018877 https://reactome.org/PathwayBrowser/#/R-DRE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9020252 https://reactome.org/PathwayBrowser/#/R-DRE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9020253 https://reactome.org/PathwayBrowser/#/R-DRE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9020257 https://reactome.org/PathwayBrowser/#/R-DRE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9020258 https://reactome.org/PathwayBrowser/#/R-DRE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9020270 https://reactome.org/PathwayBrowser/#/R-DRE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9024890 https://reactome.org/PathwayBrowser/#/R-DRE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9024993 https://reactome.org/PathwayBrowser/#/R-DRE-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15377 R-ALL-141343 H2O [peroxisomal matrix] R-DRE-9033520 https://reactome.org/PathwayBrowser/#/R-DRE-9033520 TYSND1 cleaves TYSND1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-936802 https://reactome.org/PathwayBrowser/#/R-DRE-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-936897 https://reactome.org/PathwayBrowser/#/R-DRE-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-939763 https://reactome.org/PathwayBrowser/#/R-DRE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-947591 https://reactome.org/PathwayBrowser/#/R-DRE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9624893 https://reactome.org/PathwayBrowser/#/R-DRE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9638046 https://reactome.org/PathwayBrowser/#/R-DRE-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9647994 https://reactome.org/PathwayBrowser/#/R-DRE-9647994 RAS proteins are depalmitoylated IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9656891 https://reactome.org/PathwayBrowser/#/R-DRE-9656891 OPN1SW binds 11cRAL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9656893 https://reactome.org/PathwayBrowser/#/R-DRE-9656893 OPN1MW binds 11cRAL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9658445 https://reactome.org/PathwayBrowser/#/R-DRE-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9667952 https://reactome.org/PathwayBrowser/#/R-DRE-9667952 ANKLE2 is deacetylated by SIRT2 IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-9673053 https://reactome.org/PathwayBrowser/#/R-DRE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-9673054 https://reactome.org/PathwayBrowser/#/R-DRE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9693282 https://reactome.org/PathwayBrowser/#/R-DRE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Danio rerio 15377 R-ALL-109276 H2O [extracellular region] R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9727567 https://reactome.org/PathwayBrowser/#/R-DRE-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9750546 https://reactome.org/PathwayBrowser/#/R-DRE-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9750617 https://reactome.org/PathwayBrowser/#/R-DRE-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9750656 https://reactome.org/PathwayBrowser/#/R-DRE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753278 https://reactome.org/PathwayBrowser/#/R-DRE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753280 https://reactome.org/PathwayBrowser/#/R-DRE-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753283 https://reactome.org/PathwayBrowser/#/R-DRE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753284 https://reactome.org/PathwayBrowser/#/R-DRE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9753632 https://reactome.org/PathwayBrowser/#/R-DRE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9754964 https://reactome.org/PathwayBrowser/#/R-DRE-9754964 ADA deamidates RBV IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9755030 https://reactome.org/PathwayBrowser/#/R-DRE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-977324 https://reactome.org/PathwayBrowser/#/R-DRE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-9839105 https://reactome.org/PathwayBrowser/#/R-DRE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-9839113 https://reactome.org/PathwayBrowser/#/R-DRE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Danio rerio 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-DRE-9840408 https://reactome.org/PathwayBrowser/#/R-DRE-9840408 OMA1 cleaves DELE1 IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-9861626 https://reactome.org/PathwayBrowser/#/R-DRE-9861626 SIRT4 cleaves lipoyl from DLAT IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9861725 https://reactome.org/PathwayBrowser/#/R-DRE-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9865226 https://reactome.org/PathwayBrowser/#/R-DRE-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9912636 https://reactome.org/PathwayBrowser/#/R-DRE-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9912655 https://reactome.org/PathwayBrowser/#/R-DRE-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9912747 https://reactome.org/PathwayBrowser/#/R-DRE-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9912751 https://reactome.org/PathwayBrowser/#/R-DRE-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9915968 https://reactome.org/PathwayBrowser/#/R-DRE-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9915971 https://reactome.org/PathwayBrowser/#/R-DRE-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9915986 https://reactome.org/PathwayBrowser/#/R-DRE-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-DRE-9915993 https://reactome.org/PathwayBrowser/#/R-DRE-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9915994 https://reactome.org/PathwayBrowser/#/R-DRE-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9915997 https://reactome.org/PathwayBrowser/#/R-DRE-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-DRE-9916401 https://reactome.org/PathwayBrowser/#/R-DRE-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Danio rerio 15377 R-ALL-113521 H2O [mitochondrial matrix] R-DRE-9929439 https://reactome.org/PathwayBrowser/#/R-DRE-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Danio rerio 15377 R-ALL-113518 H2O [nucleoplasm] R-DRE-997326 https://reactome.org/PathwayBrowser/#/R-DRE-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Danio rerio 15377 R-ALL-29356 H2O [cytosol] R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-109278 https://reactome.org/PathwayBrowser/#/R-GGA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-109291 https://reactome.org/PathwayBrowser/#/R-GGA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-109380 https://reactome.org/PathwayBrowser/#/R-GGA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-109387 https://reactome.org/PathwayBrowser/#/R-GGA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-109415 https://reactome.org/PathwayBrowser/#/R-GGA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-109449 https://reactome.org/PathwayBrowser/#/R-GGA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-109514 https://reactome.org/PathwayBrowser/#/R-GGA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-111879 https://reactome.org/PathwayBrowser/#/R-GGA-111879 PIP2 hydrolysis IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-111955 https://reactome.org/PathwayBrowser/#/R-GGA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-111962 https://reactome.org/PathwayBrowser/#/R-GGA-111962 PDE4A,C,D hydrolyse cAMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-112037 https://reactome.org/PathwayBrowser/#/R-GGA-112037 Inactivation of PLC beta IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1169192 https://reactome.org/PathwayBrowser/#/R-GGA-1169192 PTP1B dephosphorylates GHR IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1183128 https://reactome.org/PathwayBrowser/#/R-GGA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1237129 https://reactome.org/PathwayBrowser/#/R-GGA-1237129 Acireductone is created IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1247910 https://reactome.org/PathwayBrowser/#/R-GGA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1369028 https://reactome.org/PathwayBrowser/#/R-GGA-1369028 ABCAs mediate lipid efflux IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1369052 https://reactome.org/PathwayBrowser/#/R-GGA-1369052 ABCAs mediate lipid influx IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1369065 https://reactome.org/PathwayBrowser/#/R-GGA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-140359 https://reactome.org/PathwayBrowser/#/R-GGA-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1454916 https://reactome.org/PathwayBrowser/#/R-GGA-1454916 The ABCC family mediates organic anion transport IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1454928 https://reactome.org/PathwayBrowser/#/R-GGA-1454928 ABCG4 may mediate cholesterol efflux IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1467457 https://reactome.org/PathwayBrowser/#/R-GGA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1467466 https://reactome.org/PathwayBrowser/#/R-GGA-1467466 ABCA4 mediates atRAL transport IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1474146 https://reactome.org/PathwayBrowser/#/R-GGA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482543 https://reactome.org/PathwayBrowser/#/R-GGA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482604 https://reactome.org/PathwayBrowser/#/R-GGA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482612 https://reactome.org/PathwayBrowser/#/R-GGA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482656 https://reactome.org/PathwayBrowser/#/R-GGA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482679 https://reactome.org/PathwayBrowser/#/R-GGA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482685 https://reactome.org/PathwayBrowser/#/R-GGA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1482745 https://reactome.org/PathwayBrowser/#/R-GGA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1482759 https://reactome.org/PathwayBrowser/#/R-GGA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482771 https://reactome.org/PathwayBrowser/#/R-GGA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482776 https://reactome.org/PathwayBrowser/#/R-GGA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482777 https://reactome.org/PathwayBrowser/#/R-GGA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482811 https://reactome.org/PathwayBrowser/#/R-GGA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482816 https://reactome.org/PathwayBrowser/#/R-GGA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482825 https://reactome.org/PathwayBrowser/#/R-GGA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482828 https://reactome.org/PathwayBrowser/#/R-GGA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1482847 https://reactome.org/PathwayBrowser/#/R-GGA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482856 https://reactome.org/PathwayBrowser/#/R-GGA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482862 https://reactome.org/PathwayBrowser/#/R-GGA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482868 https://reactome.org/PathwayBrowser/#/R-GGA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482884 https://reactome.org/PathwayBrowser/#/R-GGA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482887 https://reactome.org/PathwayBrowser/#/R-GGA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482897 https://reactome.org/PathwayBrowser/#/R-GGA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482900 https://reactome.org/PathwayBrowser/#/R-GGA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482907 https://reactome.org/PathwayBrowser/#/R-GGA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482920 https://reactome.org/PathwayBrowser/#/R-GGA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1482932 https://reactome.org/PathwayBrowser/#/R-GGA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1483096 https://reactome.org/PathwayBrowser/#/R-GGA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1483159 https://reactome.org/PathwayBrowser/#/R-GGA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1483182 https://reactome.org/PathwayBrowser/#/R-GGA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1483203 https://reactome.org/PathwayBrowser/#/R-GGA-1483203 PA is dephosphorylated to DAG by LPIN IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-159425 https://reactome.org/PathwayBrowser/#/R-GGA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602368 https://reactome.org/PathwayBrowser/#/R-GGA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602374 https://reactome.org/PathwayBrowser/#/R-GGA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602377 https://reactome.org/PathwayBrowser/#/R-GGA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602398 https://reactome.org/PathwayBrowser/#/R-GGA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602399 https://reactome.org/PathwayBrowser/#/R-GGA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602417 https://reactome.org/PathwayBrowser/#/R-GGA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-1602446 https://reactome.org/PathwayBrowser/#/R-GGA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605591 https://reactome.org/PathwayBrowser/#/R-GGA-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605624 https://reactome.org/PathwayBrowser/#/R-GGA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605632 https://reactome.org/PathwayBrowser/#/R-GGA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1605723 https://reactome.org/PathwayBrowser/#/R-GGA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605724 https://reactome.org/PathwayBrowser/#/R-GGA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605736 https://reactome.org/PathwayBrowser/#/R-GGA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1605768 https://reactome.org/PathwayBrowser/#/R-GGA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1606312 https://reactome.org/PathwayBrowser/#/R-GGA-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1606564 https://reactome.org/PathwayBrowser/#/R-GGA-1606564 GALC hydrolyzes GalCer IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1606583 https://reactome.org/PathwayBrowser/#/R-GGA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1606602 https://reactome.org/PathwayBrowser/#/R-GGA-1606602 ASAH1 hydrolyzes ceramide IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1606789 https://reactome.org/PathwayBrowser/#/R-GGA-1606789 ARSB hydrolyses DS IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-1606839 https://reactome.org/PathwayBrowser/#/R-GGA-1606839 ARSC hydrolyzes steroid sulfates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1614524 https://reactome.org/PathwayBrowser/#/R-GGA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1614583 https://reactome.org/PathwayBrowser/#/R-GGA-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to pyruvate and H2S IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-162425 https://reactome.org/PathwayBrowser/#/R-GGA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-162857 https://reactome.org/PathwayBrowser/#/R-GGA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1630304 https://reactome.org/PathwayBrowser/#/R-GGA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1630306 https://reactome.org/PathwayBrowser/#/R-GGA-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1638032 https://reactome.org/PathwayBrowser/#/R-GGA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1638053 https://reactome.org/PathwayBrowser/#/R-GGA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1638821 https://reactome.org/PathwayBrowser/#/R-GGA-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-164832 https://reactome.org/PathwayBrowser/#/R-GGA-164832 ATPase synthesizes ATP IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1667005 https://reactome.org/PathwayBrowser/#/R-GGA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675795 https://reactome.org/PathwayBrowser/#/R-GGA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675824 https://reactome.org/PathwayBrowser/#/R-GGA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675836 https://reactome.org/PathwayBrowser/#/R-GGA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675949 https://reactome.org/PathwayBrowser/#/R-GGA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675988 https://reactome.org/PathwayBrowser/#/R-GGA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1675994 https://reactome.org/PathwayBrowser/#/R-GGA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676005 https://reactome.org/PathwayBrowser/#/R-GGA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676020 https://reactome.org/PathwayBrowser/#/R-GGA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676065 https://reactome.org/PathwayBrowser/#/R-GGA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676105 https://reactome.org/PathwayBrowser/#/R-GGA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676114 https://reactome.org/PathwayBrowser/#/R-GGA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676124 https://reactome.org/PathwayBrowser/#/R-GGA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676141 https://reactome.org/PathwayBrowser/#/R-GGA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676149 https://reactome.org/PathwayBrowser/#/R-GGA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676162 https://reactome.org/PathwayBrowser/#/R-GGA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676164 https://reactome.org/PathwayBrowser/#/R-GGA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676174 https://reactome.org/PathwayBrowser/#/R-GGA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676177 https://reactome.org/PathwayBrowser/#/R-GGA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676203 https://reactome.org/PathwayBrowser/#/R-GGA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1676204 https://reactome.org/PathwayBrowser/#/R-GGA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1678650 https://reactome.org/PathwayBrowser/#/R-GGA-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1678708 https://reactome.org/PathwayBrowser/#/R-GGA-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1678716 https://reactome.org/PathwayBrowser/#/R-GGA-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1678742 https://reactome.org/PathwayBrowser/#/R-GGA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1678854 https://reactome.org/PathwayBrowser/#/R-GGA-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-170158 https://reactome.org/PathwayBrowser/#/R-GGA-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-170161 https://reactome.org/PathwayBrowser/#/R-GGA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-173739 https://reactome.org/PathwayBrowser/#/R-GGA-173739 Spontaneous hydrolysis of C3 thioester IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-174110 https://reactome.org/PathwayBrowser/#/R-GGA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-174124 https://reactome.org/PathwayBrowser/#/R-GGA-174124 Dephosphorylation of phospho-Cdh1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-174391 https://reactome.org/PathwayBrowser/#/R-GGA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-174401 https://reactome.org/PathwayBrowser/#/R-GGA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-174439 https://reactome.org/PathwayBrowser/#/R-GGA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-176606 https://reactome.org/PathwayBrowser/#/R-GGA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-177923 https://reactome.org/PathwayBrowser/#/R-GGA-177923 Sustained activation of SRC kinase by SHP2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-177924 https://reactome.org/PathwayBrowser/#/R-GGA-177924 Dephosphorylation of Gab1 by SHP2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-177926 https://reactome.org/PathwayBrowser/#/R-GGA-177926 Dephosphorylation of PAG by SHP2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-177935 https://reactome.org/PathwayBrowser/#/R-GGA-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1793182 https://reactome.org/PathwayBrowser/#/R-GGA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1793186 https://reactome.org/PathwayBrowser/#/R-GGA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1793207 https://reactome.org/PathwayBrowser/#/R-GGA-1793207 ARSB hydrolyses C4S/C6S chains IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-1793209 https://reactome.org/PathwayBrowser/#/R-GGA-1793209 HYAL1 hydrolyses Chondroitin chains IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855154 https://reactome.org/PathwayBrowser/#/R-GGA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855159 https://reactome.org/PathwayBrowser/#/R-GGA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-1855163 https://reactome.org/PathwayBrowser/#/R-GGA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855165 https://reactome.org/PathwayBrowser/#/R-GGA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855166 https://reactome.org/PathwayBrowser/#/R-GGA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855171 https://reactome.org/PathwayBrowser/#/R-GGA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855174 https://reactome.org/PathwayBrowser/#/R-GGA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855177 https://reactome.org/PathwayBrowser/#/R-GGA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855180 https://reactome.org/PathwayBrowser/#/R-GGA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855198 https://reactome.org/PathwayBrowser/#/R-GGA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-1855200 https://reactome.org/PathwayBrowser/#/R-GGA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855202 https://reactome.org/PathwayBrowser/#/R-GGA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855205 https://reactome.org/PathwayBrowser/#/R-GGA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855208 https://reactome.org/PathwayBrowser/#/R-GGA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855210 https://reactome.org/PathwayBrowser/#/R-GGA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855211 https://reactome.org/PathwayBrowser/#/R-GGA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855213 https://reactome.org/PathwayBrowser/#/R-GGA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855214 https://reactome.org/PathwayBrowser/#/R-GGA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855218 https://reactome.org/PathwayBrowser/#/R-GGA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855219 https://reactome.org/PathwayBrowser/#/R-GGA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855221 https://reactome.org/PathwayBrowser/#/R-GGA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855222 https://reactome.org/PathwayBrowser/#/R-GGA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-1855225 https://reactome.org/PathwayBrowser/#/R-GGA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1855232 https://reactome.org/PathwayBrowser/#/R-GGA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-1861788 https://reactome.org/PathwayBrowser/#/R-GGA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-187632 https://reactome.org/PathwayBrowser/#/R-GGA-187632 arginine + H2O => ornithine + urea TAS Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-188979 https://reactome.org/PathwayBrowser/#/R-GGA-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-189053 https://reactome.org/PathwayBrowser/#/R-GGA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-189062 https://reactome.org/PathwayBrowser/#/R-GGA-189062 lactose + H2O => D-glucose + D-galactose IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-189069 https://reactome.org/PathwayBrowser/#/R-GGA-189069 sucrose + H2O => glucose + fructose IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-189102 https://reactome.org/PathwayBrowser/#/R-GGA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-189406 https://reactome.org/PathwayBrowser/#/R-GGA-189406 4 PBGs bind to form HMB IEA Gallus gallus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-189488 https://reactome.org/PathwayBrowser/#/R-GGA-189488 UROS transforms HMB to URO3 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-191101 https://reactome.org/PathwayBrowser/#/R-GGA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-191108 https://reactome.org/PathwayBrowser/#/R-GGA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-191114 https://reactome.org/PathwayBrowser/#/R-GGA-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-191116 https://reactome.org/PathwayBrowser/#/R-GGA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-192331 https://reactome.org/PathwayBrowser/#/R-GGA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-192417 https://reactome.org/PathwayBrowser/#/R-GGA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-192422 https://reactome.org/PathwayBrowser/#/R-GGA-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-192425 https://reactome.org/PathwayBrowser/#/R-GGA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-192430 https://reactome.org/PathwayBrowser/#/R-GGA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-192434 https://reactome.org/PathwayBrowser/#/R-GGA-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193362 https://reactome.org/PathwayBrowser/#/R-GGA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-193385 https://reactome.org/PathwayBrowser/#/R-GGA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-193535 https://reactome.org/PathwayBrowser/#/R-GGA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193711 https://reactome.org/PathwayBrowser/#/R-GGA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193727 https://reactome.org/PathwayBrowser/#/R-GGA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193743 https://reactome.org/PathwayBrowser/#/R-GGA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193766 https://reactome.org/PathwayBrowser/#/R-GGA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-196950 https://reactome.org/PathwayBrowser/#/R-GGA-196950 2xTRAP hydrolyzes FMN to RIB IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-197186 https://reactome.org/PathwayBrowser/#/R-GGA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-199425 https://reactome.org/PathwayBrowser/#/R-GGA-199425 PHLPP dephosphorylates S473 in AKT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-199456 https://reactome.org/PathwayBrowser/#/R-GGA-199456 PTEN dephosphorylates PIP3 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-200661 https://reactome.org/PathwayBrowser/#/R-GGA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-200740 https://reactome.org/PathwayBrowser/#/R-GGA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-201035 https://reactome.org/PathwayBrowser/#/R-GGA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-202214 https://reactome.org/PathwayBrowser/#/R-GGA-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022368 https://reactome.org/PathwayBrowser/#/R-GGA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-202237 https://reactome.org/PathwayBrowser/#/R-GGA-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022378 https://reactome.org/PathwayBrowser/#/R-GGA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022379 https://reactome.org/PathwayBrowser/#/R-GGA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022381 https://reactome.org/PathwayBrowser/#/R-GGA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022383 https://reactome.org/PathwayBrowser/#/R-GGA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022396 https://reactome.org/PathwayBrowser/#/R-GGA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022398 https://reactome.org/PathwayBrowser/#/R-GGA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022399 https://reactome.org/PathwayBrowser/#/R-GGA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022403 https://reactome.org/PathwayBrowser/#/R-GGA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022405 https://reactome.org/PathwayBrowser/#/R-GGA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022411 https://reactome.org/PathwayBrowser/#/R-GGA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2022412 https://reactome.org/PathwayBrowser/#/R-GGA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-ALL-2022884 H2O [Golgi lumen] R-GGA-2022887 https://reactome.org/PathwayBrowser/#/R-GGA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2023971 https://reactome.org/PathwayBrowser/#/R-GGA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2023973 https://reactome.org/PathwayBrowser/#/R-GGA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-202407 https://reactome.org/PathwayBrowser/#/R-GGA-202407 PLC-gamma1 hydrolyses PIP2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2029468 https://reactome.org/PathwayBrowser/#/R-GGA-2029468 Conversion of PA into DAG by PAP-1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2029475 https://reactome.org/PathwayBrowser/#/R-GGA-2029475 Production of AA by iPLA2 upon FCGR activation IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 Depalmitoylation of eNOS IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-203797 https://reactome.org/PathwayBrowser/#/R-GGA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-204169 https://reactome.org/PathwayBrowser/#/R-GGA-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046083 https://reactome.org/PathwayBrowser/#/R-GGA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046088 https://reactome.org/PathwayBrowser/#/R-GGA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046090 https://reactome.org/PathwayBrowser/#/R-GGA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046094 https://reactome.org/PathwayBrowser/#/R-GGA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046095 https://reactome.org/PathwayBrowser/#/R-GGA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2046100 https://reactome.org/PathwayBrowser/#/R-GGA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2065355 https://reactome.org/PathwayBrowser/#/R-GGA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2065357 https://reactome.org/PathwayBrowser/#/R-GGA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-2066778 https://reactome.org/PathwayBrowser/#/R-GGA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-2066779 https://reactome.org/PathwayBrowser/#/R-GGA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2090037 https://reactome.org/PathwayBrowser/#/R-GGA-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2090038 https://reactome.org/PathwayBrowser/#/R-GGA-2090038 NAGLU hydrolyses heparan chain(2) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2090043 https://reactome.org/PathwayBrowser/#/R-GGA-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2090079 https://reactome.org/PathwayBrowser/#/R-GGA-2090079 GLB1 hydrolyses linker chain(2) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15377 R-ALL-351603 H2O [secretory granule lumen] R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2105001 https://reactome.org/PathwayBrowser/#/R-GGA-2105001 HEXA cleaves the terminal GalNAc from DS IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2130725 https://reactome.org/PathwayBrowser/#/R-GGA-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2132047 https://reactome.org/PathwayBrowser/#/R-GGA-2132047 Spontaneous hydrolysis of an internal thioester bond in complement factor C3 TAS Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2160874 https://reactome.org/PathwayBrowser/#/R-GGA-2160874 HYAL1 hydrolyses (HA)50 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161195 https://reactome.org/PathwayBrowser/#/R-GGA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161959 https://reactome.org/PathwayBrowser/#/R-GGA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161961 https://reactome.org/PathwayBrowser/#/R-GGA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2161999 https://reactome.org/PathwayBrowser/#/R-GGA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-2162187 https://reactome.org/PathwayBrowser/#/R-GGA-2162187 COQ6 hydroxylates DHB IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2162225 https://reactome.org/PathwayBrowser/#/R-GGA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2162226 https://reactome.org/PathwayBrowser/#/R-GGA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-2162227 https://reactome.org/PathwayBrowser/#/R-GGA-2162227 GUSB tetramer hydrolyses (HA)2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-216723 https://reactome.org/PathwayBrowser/#/R-GGA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-216757 https://reactome.org/PathwayBrowser/#/R-GGA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2187401 https://reactome.org/PathwayBrowser/#/R-GGA-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-2309773 https://reactome.org/PathwayBrowser/#/R-GGA-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2393939 https://reactome.org/PathwayBrowser/#/R-GGA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-2393954 https://reactome.org/PathwayBrowser/#/R-GGA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2408551 https://reactome.org/PathwayBrowser/#/R-GGA-2408551 SeMet is converted to AdoSeMet by MAT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2454118 https://reactome.org/PathwayBrowser/#/R-GGA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2465924 https://reactome.org/PathwayBrowser/#/R-GGA-2465924 OPN1LW binds 11cRAL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2466085 https://reactome.org/PathwayBrowser/#/R-GGA-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2529015 https://reactome.org/PathwayBrowser/#/R-GGA-2529015 Dephosphorylation of CK2-modified condensin I IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2632521 https://reactome.org/PathwayBrowser/#/R-GGA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-265783 https://reactome.org/PathwayBrowser/#/R-GGA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-266012 https://reactome.org/PathwayBrowser/#/R-GGA-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-266046 https://reactome.org/PathwayBrowser/#/R-GGA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-266051 https://reactome.org/PathwayBrowser/#/R-GGA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-266070 https://reactome.org/PathwayBrowser/#/R-GGA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-266072 https://reactome.org/PathwayBrowser/#/R-GGA-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-266082 https://reactome.org/PathwayBrowser/#/R-GGA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2730847 https://reactome.org/PathwayBrowser/#/R-GGA-2730847 Hydrolysis of PIP2 by PLCG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2730849 https://reactome.org/PathwayBrowser/#/R-GGA-2730849 Calcineurin binds and dephosphorylates NFAT IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2855047 https://reactome.org/PathwayBrowser/#/R-GGA-2855047 Hydrolysis of internal thioester in C4b IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-2859050 https://reactome.org/PathwayBrowser/#/R-GGA-2859050 Hydrolysis of C4b IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-2995330 https://reactome.org/PathwayBrowser/#/R-GGA-2995330 COX10 transforms heme to heme O IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-2995334 https://reactome.org/PathwayBrowser/#/R-GGA-2995334 COX15 transforms heme O to heme A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-2995388 https://reactome.org/PathwayBrowser/#/R-GGA-2995388 PP2A dephosphorylates BANF1 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3002811 https://reactome.org/PathwayBrowser/#/R-GGA-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3095901 https://reactome.org/PathwayBrowser/#/R-GGA-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-3262512 https://reactome.org/PathwayBrowser/#/R-GGA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-3266566 https://reactome.org/PathwayBrowser/#/R-GGA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-3322995 https://reactome.org/PathwayBrowser/#/R-GGA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3341277 https://reactome.org/PathwayBrowser/#/R-GGA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-3341296 https://reactome.org/PathwayBrowser/#/R-GGA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3341343 https://reactome.org/PathwayBrowser/#/R-GGA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-3341397 https://reactome.org/PathwayBrowser/#/R-GGA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3371467 https://reactome.org/PathwayBrowser/#/R-GGA-3371467 SIRT1 deacetylates HSF1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-350604 https://reactome.org/PathwayBrowser/#/R-GGA-350604 Agmatine + H2O <=> putrescine + urea IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-352981 https://reactome.org/PathwayBrowser/#/R-GGA-352981 phosphoenolpyruvate + H2O <=> 2-phosphoglycerate TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-353044 https://reactome.org/PathwayBrowser/#/R-GGA-353044 2-phosphoglycerate <=> phosphoenolpyruvate + H2O TAS Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-353058 https://reactome.org/PathwayBrowser/#/R-GGA-353058 glucose 6-phosphate + H2O => glucose + phosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3640872 https://reactome.org/PathwayBrowser/#/R-GGA-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-372388 https://reactome.org/PathwayBrowser/#/R-GGA-372388 fructose 1,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-372425 https://reactome.org/PathwayBrowser/#/R-GGA-372425 fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate TAS Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-372519 https://reactome.org/PathwayBrowser/#/R-GGA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-373006 https://reactome.org/PathwayBrowser/#/R-GGA-373006 acetyl-CoA + H2O + oxaloacetate => citrate + CoA TAS Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-373141 https://reactome.org/PathwayBrowser/#/R-GGA-373141 malate <=> fumarate + H2O TAS Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-373145 https://reactome.org/PathwayBrowser/#/R-GGA-373145 fumarate + H2O <=> malate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3769447 https://reactome.org/PathwayBrowser/#/R-GGA-3769447 HDAC1:2-containing complex deacetylate histones IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-377643 https://reactome.org/PathwayBrowser/#/R-GGA-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3777129 https://reactome.org/PathwayBrowser/#/R-GGA-3777129 HDAC3 containing complexes deacetylate histone IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3781011 https://reactome.org/PathwayBrowser/#/R-GGA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-3781018 https://reactome.org/PathwayBrowser/#/R-GGA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3782637 https://reactome.org/PathwayBrowser/#/R-GGA-3782637 HDAC8 deacetylates histones IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-3782655 https://reactome.org/PathwayBrowser/#/R-GGA-3782655 HDAC10 deacetylates histone IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-380949 https://reactome.org/PathwayBrowser/#/R-GGA-380949 AMPK is dephosphorylated IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-382560 https://reactome.org/PathwayBrowser/#/R-GGA-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-382575 https://reactome.org/PathwayBrowser/#/R-GGA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-383190 https://reactome.org/PathwayBrowser/#/R-GGA-383190 HCO3- transport through ion channel IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-389986 https://reactome.org/PathwayBrowser/#/R-GGA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-390252 https://reactome.org/PathwayBrowser/#/R-GGA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-399998 https://reactome.org/PathwayBrowser/#/R-GGA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4084976 https://reactome.org/PathwayBrowser/#/R-GGA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4084989 https://reactome.org/PathwayBrowser/#/R-GGA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4084994 https://reactome.org/PathwayBrowser/#/R-GGA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4085021 https://reactome.org/PathwayBrowser/#/R-GGA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4085029 https://reactome.org/PathwayBrowser/#/R-GGA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4086392 https://reactome.org/PathwayBrowser/#/R-GGA-4086392 PDE6 hydrolyses cGMP to GMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4093339 https://reactome.org/PathwayBrowser/#/R-GGA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-416559 https://reactome.org/PathwayBrowser/#/R-GGA-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-418553 https://reactome.org/PathwayBrowser/#/R-GGA-418553 cAMP degradation by Phosphodiesterases IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-419144 https://reactome.org/PathwayBrowser/#/R-GGA-419144 5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-419152 https://reactome.org/PathwayBrowser/#/R-GGA-419152 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-419253 https://reactome.org/PathwayBrowser/#/R-GGA-419253 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) <=> inosine 5'-monophosphate + H2O TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-419440 https://reactome.org/PathwayBrowser/#/R-GGA-419440 L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421179 https://reactome.org/PathwayBrowser/#/R-GGA-421179 inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421218 https://reactome.org/PathwayBrowser/#/R-GGA-421218 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421439 https://reactome.org/PathwayBrowser/#/R-GGA-421439 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 IEA Gallus gallus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421471 https://reactome.org/PathwayBrowser/#/R-GGA-421471 hydroxymethylbilane => uroporphyrinogen I + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421472 https://reactome.org/PathwayBrowser/#/R-GGA-421472 2 delta-aminolevulinate => porphobilinogen + 2 H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-421482 https://reactome.org/PathwayBrowser/#/R-GGA-421482 hydroxymethylbilane => uroporphyrinogen III + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428205 https://reactome.org/PathwayBrowser/#/R-GGA-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428231 https://reactome.org/PathwayBrowser/#/R-GGA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428262 https://reactome.org/PathwayBrowser/#/R-GGA-428262 ACER3 hydrolyzes phytoceramide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428664 https://reactome.org/PathwayBrowser/#/R-GGA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-428690 https://reactome.org/PathwayBrowser/#/R-GGA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-428696 https://reactome.org/PathwayBrowser/#/R-GGA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-429860 https://reactome.org/PathwayBrowser/#/R-GGA-429860 DCP1-DCP2 complex decaps mRNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-429955 https://reactome.org/PathwayBrowser/#/R-GGA-429955 CCR4-NOT complex deadenylates mRNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-429961 https://reactome.org/PathwayBrowser/#/R-GGA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-429992 https://reactome.org/PathwayBrowser/#/R-GGA-429992 PARN deadenylates mRNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-430021 https://reactome.org/PathwayBrowser/#/R-GGA-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-430028 https://reactome.org/PathwayBrowser/#/R-GGA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-432010 https://reactome.org/PathwayBrowser/#/R-GGA-432010 Aquaporin-1 passively transports water into cell IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-432010 https://reactome.org/PathwayBrowser/#/R-GGA-432010 Aquaporin-1 passively transports water into cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-432054 https://reactome.org/PathwayBrowser/#/R-GGA-432054 Aquaporin-1 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-432054 https://reactome.org/PathwayBrowser/#/R-GGA-432054 Aquaporin-1 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-432065 https://reactome.org/PathwayBrowser/#/R-GGA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-432065 https://reactome.org/PathwayBrowser/#/R-GGA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-432067 https://reactome.org/PathwayBrowser/#/R-GGA-432067 Aquaporin-4 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-432067 https://reactome.org/PathwayBrowser/#/R-GGA-432067 Aquaporin-4 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-433578 https://reactome.org/PathwayBrowser/#/R-GGA-433578 phytoceramide + H2O => stearate + phytosphingosine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-433608 https://reactome.org/PathwayBrowser/#/R-GGA-433608 ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-445714 https://reactome.org/PathwayBrowser/#/R-GGA-445714 Aquaporin-3 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-445714 https://reactome.org/PathwayBrowser/#/R-GGA-445714 Aquaporin-3 passively transports water out of cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-449937 https://reactome.org/PathwayBrowser/#/R-GGA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-452036 https://reactome.org/PathwayBrowser/#/R-GGA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4551451 https://reactome.org/PathwayBrowser/#/R-GGA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-4641236 https://reactome.org/PathwayBrowser/#/R-GGA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-507868 https://reactome.org/PathwayBrowser/#/R-GGA-507868 Aquaporins passively transport water into cells IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-507870 https://reactome.org/PathwayBrowser/#/R-GGA-507870 Aquaporins passively transport water out of cells IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5221130 https://reactome.org/PathwayBrowser/#/R-GGA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5223313 https://reactome.org/PathwayBrowser/#/R-GGA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5223317 https://reactome.org/PathwayBrowser/#/R-GGA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5251989 https://reactome.org/PathwayBrowser/#/R-GGA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5362459 https://reactome.org/PathwayBrowser/#/R-GGA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5433072 https://reactome.org/PathwayBrowser/#/R-GGA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5433074 https://reactome.org/PathwayBrowser/#/R-GGA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-548843 https://reactome.org/PathwayBrowser/#/R-GGA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5603114 https://reactome.org/PathwayBrowser/#/R-GGA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5607735 https://reactome.org/PathwayBrowser/#/R-GGA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5618093 https://reactome.org/PathwayBrowser/#/R-GGA-5618093 ATP hydrolysis by HSP90 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5623513 https://reactome.org/PathwayBrowser/#/R-GGA-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5628905 https://reactome.org/PathwayBrowser/#/R-GGA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5631885 https://reactome.org/PathwayBrowser/#/R-GGA-5631885 PRDX1 overoxidizes IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5651828 https://reactome.org/PathwayBrowser/#/R-GGA-5651828 PARG dePARylates PARP1,PARP2 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5653770 https://reactome.org/PathwayBrowser/#/R-GGA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5659861 https://reactome.org/PathwayBrowser/#/R-GGA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Gallus gallus 15377 R-ALL-5668574 H2O [melanosome lumen] R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5675373 https://reactome.org/PathwayBrowser/#/R-GGA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5675376 https://reactome.org/PathwayBrowser/#/R-GGA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5676637 https://reactome.org/PathwayBrowser/#/R-GGA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5678706 https://reactome.org/PathwayBrowser/#/R-GGA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5678863 https://reactome.org/PathwayBrowser/#/R-GGA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5679041 https://reactome.org/PathwayBrowser/#/R-GGA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5682285 https://reactome.org/PathwayBrowser/#/R-GGA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5683714 https://reactome.org/PathwayBrowser/#/R-GGA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5683967 https://reactome.org/PathwayBrowser/#/R-GGA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Gallus gallus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-GGA-5684864 https://reactome.org/PathwayBrowser/#/R-GGA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Gallus gallus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-GGA-5685902 https://reactome.org/PathwayBrowser/#/R-GGA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5685994 https://reactome.org/PathwayBrowser/#/R-GGA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5687464 https://reactome.org/PathwayBrowser/#/R-GGA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5687664 https://reactome.org/PathwayBrowser/#/R-GGA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5687758 https://reactome.org/PathwayBrowser/#/R-GGA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5688797 https://reactome.org/PathwayBrowser/#/R-GGA-5688797 ATXN3 family cleave Ub chains IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5688837 https://reactome.org/PathwayBrowser/#/R-GGA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5689000 https://reactome.org/PathwayBrowser/#/R-GGA-5689000 AADAC deacetylates PHEN IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5689950 https://reactome.org/PathwayBrowser/#/R-GGA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690043 https://reactome.org/PathwayBrowser/#/R-GGA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5690066 https://reactome.org/PathwayBrowser/#/R-GGA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690152 https://reactome.org/PathwayBrowser/#/R-GGA-5690152 USP5 cleaves polyubiquitin IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5690157 https://reactome.org/PathwayBrowser/#/R-GGA-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690196 https://reactome.org/PathwayBrowser/#/R-GGA-5690196 USP8 deubiquitinates RNF128 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690319 https://reactome.org/PathwayBrowser/#/R-GGA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-5690517 https://reactome.org/PathwayBrowser/#/R-GGA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5690790 https://reactome.org/PathwayBrowser/#/R-GGA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690808 https://reactome.org/PathwayBrowser/#/R-GGA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690856 https://reactome.org/PathwayBrowser/#/R-GGA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5690870 https://reactome.org/PathwayBrowser/#/R-GGA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5691381 https://reactome.org/PathwayBrowser/#/R-GGA-5691381 MYSM1 deubiquitinates Histone H2A IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5691411 https://reactome.org/PathwayBrowser/#/R-GGA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5691439 https://reactome.org/PathwayBrowser/#/R-GGA-5691439 BRISC complex deubiquitinates NLRP3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5691507 https://reactome.org/PathwayBrowser/#/R-GGA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5691512 https://reactome.org/PathwayBrowser/#/R-GGA-5691512 APEH hydrolyses NAc-Ser-protein IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5692462 https://reactome.org/PathwayBrowser/#/R-GGA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5692480 https://reactome.org/PathwayBrowser/#/R-GGA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5692754 https://reactome.org/PathwayBrowser/#/R-GGA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5693153 https://reactome.org/PathwayBrowser/#/R-GGA-5693153 PPM1K dephosphorylates p-BCKDH IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5693346 https://reactome.org/PathwayBrowser/#/R-GGA-5693346 CECRI deaminates Ade-Rib to Ino IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5693373 https://reactome.org/PathwayBrowser/#/R-GGA-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5693608 https://reactome.org/PathwayBrowser/#/R-GGA-5693608 Initial resection of double-strand break ends IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-5693724 https://reactome.org/PathwayBrowser/#/R-GGA-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5693742 https://reactome.org/PathwayBrowser/#/R-GGA-5693742 FAAH hydrolyses AEA to AA and ETA IEA Gallus gallus 15377 R-ALL-5693747 H2O [lipid droplet] R-GGA-5693751 https://reactome.org/PathwayBrowser/#/R-GGA-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5693783 https://reactome.org/PathwayBrowser/#/R-GGA-5693783 NAALADases hydrolyse NAAG IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-5693807 https://reactome.org/PathwayBrowser/#/R-GGA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5694077 https://reactome.org/PathwayBrowser/#/R-GGA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5694109 https://reactome.org/PathwayBrowser/#/R-GGA-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5694126 https://reactome.org/PathwayBrowser/#/R-GGA-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5694421 https://reactome.org/PathwayBrowser/#/R-GGA-5694421 PP6 dephosphorylates SEC24 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5694485 https://reactome.org/PathwayBrowser/#/R-GGA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5694563 https://reactome.org/PathwayBrowser/#/R-GGA-5694563 ABHD10 hydrolyses MPAG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5695964 https://reactome.org/PathwayBrowser/#/R-GGA-5695964 ABHD14B hydrolyses PNPB IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696049 https://reactome.org/PathwayBrowser/#/R-GGA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5696197 https://reactome.org/PathwayBrowser/#/R-GGA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696230 https://reactome.org/PathwayBrowser/#/R-GGA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696365 https://reactome.org/PathwayBrowser/#/R-GGA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5696408 https://reactome.org/PathwayBrowser/#/R-GGA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-5696415 https://reactome.org/PathwayBrowser/#/R-GGA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696534 https://reactome.org/PathwayBrowser/#/R-GGA-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5696605 https://reactome.org/PathwayBrowser/#/R-GGA-5696605 USP12, USP26 deubiquitinate AR IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696627 https://reactome.org/PathwayBrowser/#/R-GGA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696872 https://reactome.org/PathwayBrowser/#/R-GGA-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5696914 https://reactome.org/PathwayBrowser/#/R-GGA-5696914 USP28 deubiquitinates CLSPN and MYC IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696945 https://reactome.org/PathwayBrowser/#/R-GGA-5696945 USP33 deubiquitinates CCP110,ARRB IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5696958 https://reactome.org/PathwayBrowser/#/R-GGA-5696958 USP44 deubiquitinates CDC20 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5696960 https://reactome.org/PathwayBrowser/#/R-GGA-5696960 USP49 deubiquitinates H2B IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-5696968 https://reactome.org/PathwayBrowser/#/R-GGA-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5696997 https://reactome.org/PathwayBrowser/#/R-GGA-5696997 USP24 deubiquitinates DDB2 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-5697009 https://reactome.org/PathwayBrowser/#/R-GGA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6781764 https://reactome.org/PathwayBrowser/#/R-GGA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6781779 https://reactome.org/PathwayBrowser/#/R-GGA-6781779 USP13 deubiquitinates BECN1,USP10 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6781814 https://reactome.org/PathwayBrowser/#/R-GGA-6781814 USP19 deubiquitinates RNF123 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-6782069 https://reactome.org/PathwayBrowser/#/R-GGA-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6782106 https://reactome.org/PathwayBrowser/#/R-GGA-6782106 USP10 deubiquitinates SNX3, CFTR IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6782628 https://reactome.org/PathwayBrowser/#/R-GGA-6782628 USP8 deubiquitinates STAM2:HGS IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6784402 https://reactome.org/PathwayBrowser/#/R-GGA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6784959 https://reactome.org/PathwayBrowser/#/R-GGA-6784959 BPHL hydrolyses VACV to ACV IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6786190 https://reactome.org/PathwayBrowser/#/R-GGA-6786190 CMBL hydrolyses OM to OLMS IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6786421 https://reactome.org/PathwayBrowser/#/R-GGA-6786421 CHIA hydrolyses chitin IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6786650 https://reactome.org/PathwayBrowser/#/R-GGA-6786650 DDHD1,2 hydrolyse PA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6787632 https://reactome.org/PathwayBrowser/#/R-GGA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6788295 https://reactome.org/PathwayBrowser/#/R-GGA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6788912 https://reactome.org/PathwayBrowser/#/R-GGA-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Gallus gallus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6789310 https://reactome.org/PathwayBrowser/#/R-GGA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6792445 https://reactome.org/PathwayBrowser/#/R-GGA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6797627 https://reactome.org/PathwayBrowser/#/R-GGA-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6797630 https://reactome.org/PathwayBrowser/#/R-GGA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6797653 https://reactome.org/PathwayBrowser/#/R-GGA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6797913 https://reactome.org/PathwayBrowser/#/R-GGA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6797955 https://reactome.org/PathwayBrowser/#/R-GGA-6797955 ALDH7A1 oxidises BETALD to BET IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6799545 https://reactome.org/PathwayBrowser/#/R-GGA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-6799581 https://reactome.org/PathwayBrowser/#/R-GGA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6799604 https://reactome.org/PathwayBrowser/#/R-GGA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6799977 https://reactome.org/PathwayBrowser/#/R-GGA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6800299 https://reactome.org/PathwayBrowser/#/R-GGA-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6801462 https://reactome.org/PathwayBrowser/#/R-GGA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6803545 https://reactome.org/PathwayBrowser/#/R-GGA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-6803753 https://reactome.org/PathwayBrowser/#/R-GGA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6803789 https://reactome.org/PathwayBrowser/#/R-GGA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6807008 https://reactome.org/PathwayBrowser/#/R-GGA-6807008 PTPRJ dephosphorylates MET IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6807027 https://reactome.org/PathwayBrowser/#/R-GGA-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-6807118 https://reactome.org/PathwayBrowser/#/R-GGA-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6807206 https://reactome.org/PathwayBrowser/#/R-GGA-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-6809263 https://reactome.org/PathwayBrowser/#/R-GGA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6809320 https://reactome.org/PathwayBrowser/#/R-GGA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6809325 https://reactome.org/PathwayBrowser/#/R-GGA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6809720 https://reactome.org/PathwayBrowser/#/R-GGA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6809777 https://reactome.org/PathwayBrowser/#/R-GGA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6809778 https://reactome.org/PathwayBrowser/#/R-GGA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6810464 https://reactome.org/PathwayBrowser/#/R-GGA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-6810472 https://reactome.org/PathwayBrowser/#/R-GGA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6813720 https://reactome.org/PathwayBrowser/#/R-GGA-6813720 NCEH1 hydrolyzes cholesterol esters IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6813740 https://reactome.org/PathwayBrowser/#/R-GGA-6813740 GDE1 hydrolyzes GroPIns IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-6814254 https://reactome.org/PathwayBrowser/#/R-GGA-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-6814797 https://reactome.org/PathwayBrowser/#/R-GGA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-69199 https://reactome.org/PathwayBrowser/#/R-GGA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70262 https://reactome.org/PathwayBrowser/#/R-GGA-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70479 https://reactome.org/PathwayBrowser/#/R-GGA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70494 https://reactome.org/PathwayBrowser/#/R-GGA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70609 https://reactome.org/PathwayBrowser/#/R-GGA-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70785 https://reactome.org/PathwayBrowser/#/R-GGA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70903 https://reactome.org/PathwayBrowser/#/R-GGA-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-70906 https://reactome.org/PathwayBrowser/#/R-GGA-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-70982 https://reactome.org/PathwayBrowser/#/R-GGA-70982 FH tetramer hydrates fumarate to L-malate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71146 https://reactome.org/PathwayBrowser/#/R-GGA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71296 https://reactome.org/PathwayBrowser/#/R-GGA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71660 https://reactome.org/PathwayBrowser/#/R-GGA-71660 Enolase dimers dehydrates 2PG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-71732 https://reactome.org/PathwayBrowser/#/R-GGA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-71825 https://reactome.org/PathwayBrowser/#/R-GGA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73608 https://reactome.org/PathwayBrowser/#/R-GGA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73797 https://reactome.org/PathwayBrowser/#/R-GGA-73797 FAICAR => IMP + H2O IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-73815 https://reactome.org/PathwayBrowser/#/R-GGA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74241 https://reactome.org/PathwayBrowser/#/R-GGA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74248 https://reactome.org/PathwayBrowser/#/R-GGA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74733 https://reactome.org/PathwayBrowser/#/R-GGA-74733 Insulin receptor de-phosphorylation IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-74948 https://reactome.org/PathwayBrowser/#/R-GGA-74948 PP2A dephosphorylates p-RHO to RHO IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-75899 https://reactome.org/PathwayBrowser/#/R-GGA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-76590 https://reactome.org/PathwayBrowser/#/R-GGA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-77277 https://reactome.org/PathwayBrowser/#/R-GGA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-77301 https://reactome.org/PathwayBrowser/#/R-GGA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-77614 https://reactome.org/PathwayBrowser/#/R-GGA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848053 https://reactome.org/PathwayBrowser/#/R-GGA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848215 https://reactome.org/PathwayBrowser/#/R-GGA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848338 https://reactome.org/PathwayBrowser/#/R-GGA-8848338 PNPLA4 hydrolyzes TAG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848339 https://reactome.org/PathwayBrowser/#/R-GGA-8848339 PNPLA5 hydrolyzes TAG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848355 https://reactome.org/PathwayBrowser/#/R-GGA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8848484 https://reactome.org/PathwayBrowser/#/R-GGA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8849969 https://reactome.org/PathwayBrowser/#/R-GGA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8850594 https://reactome.org/PathwayBrowser/#/R-GGA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-2022884 H2O [Golgi lumen] R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-2022884 H2O [Golgi lumen] R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8852200 https://reactome.org/PathwayBrowser/#/R-GGA-8852200 Inactivation of LCK by PTPN22 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8853379 https://reactome.org/PathwayBrowser/#/R-GGA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8854173 https://reactome.org/PathwayBrowser/#/R-GGA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8854255 https://reactome.org/PathwayBrowser/#/R-GGA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8854329 https://reactome.org/PathwayBrowser/#/R-GGA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8854604 https://reactome.org/PathwayBrowser/#/R-GGA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8854612 https://reactome.org/PathwayBrowser/#/R-GGA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8855381 https://reactome.org/PathwayBrowser/#/R-GGA-8855381 PTPN22 dephosphorylates ZAP70 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8855490 https://reactome.org/PathwayBrowser/#/R-GGA-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8855825 https://reactome.org/PathwayBrowser/#/R-GGA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-8862184 https://reactome.org/PathwayBrowser/#/R-GGA-8862184 USP48 cleaves polyubiquitin IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8862320 https://reactome.org/PathwayBrowser/#/R-GGA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8863804 https://reactome.org/PathwayBrowser/#/R-GGA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8864029 https://reactome.org/PathwayBrowser/#/R-GGA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8864036 https://reactome.org/PathwayBrowser/#/R-GGA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8864125 https://reactome.org/PathwayBrowser/#/R-GGA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-8865667 https://reactome.org/PathwayBrowser/#/R-GGA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8866542 https://reactome.org/PathwayBrowser/#/R-GGA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8867047 https://reactome.org/PathwayBrowser/#/R-GGA-8867047 PTPN3 dephosphorylates EPS15 IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-8867344 https://reactome.org/PathwayBrowser/#/R-GGA-8867344 OMA1 hydrolyses OPA1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8867658 https://reactome.org/PathwayBrowser/#/R-GGA-8867658 PTPN3 dephosphorylates MAPK12 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8868648 https://reactome.org/PathwayBrowser/#/R-GGA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8868658 https://reactome.org/PathwayBrowser/#/R-GGA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8868661 https://reactome.org/PathwayBrowser/#/R-GGA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8869206 https://reactome.org/PathwayBrowser/#/R-GGA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8869425 https://reactome.org/PathwayBrowser/#/R-GGA-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8869456 https://reactome.org/PathwayBrowser/#/R-GGA-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8869506 https://reactome.org/PathwayBrowser/#/R-GGA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8875443 https://reactome.org/PathwayBrowser/#/R-GGA-8875443 USP8 deubiquitinates LRIG1 IEA Gallus gallus 15377 R-ALL-5668574 H2O [melanosome lumen] R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-8878654 https://reactome.org/PathwayBrowser/#/R-GGA-8878654 ACP6 hydrolyses MYS-LPA IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8878787 https://reactome.org/PathwayBrowser/#/R-GGA-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8932633 https://reactome.org/PathwayBrowser/#/R-GGA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8933328 https://reactome.org/PathwayBrowser/#/R-GGA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Gallus gallus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-893596 https://reactome.org/PathwayBrowser/#/R-GGA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8937442 https://reactome.org/PathwayBrowser/#/R-GGA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-8937767 https://reactome.org/PathwayBrowser/#/R-GGA-8937767 PTPN11 dephosphorylates RUNX1 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8940074 https://reactome.org/PathwayBrowser/#/R-GGA-8940074 NT5E:Zn2+ hydrolyses NMN IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8940388 https://reactome.org/PathwayBrowser/#/R-GGA-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8943279 https://reactome.org/PathwayBrowser/#/R-GGA-8943279 GGT dimers hydrolyse GSH IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8952137 https://reactome.org/PathwayBrowser/#/R-GGA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8952251 https://reactome.org/PathwayBrowser/#/R-GGA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-8952903 https://reactome.org/PathwayBrowser/#/R-GGA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Gallus gallus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-GGA-8954398 https://reactome.org/PathwayBrowser/#/R-GGA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8955794 https://reactome.org/PathwayBrowser/#/R-GGA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-8957389 https://reactome.org/PathwayBrowser/#/R-GGA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-8980228 https://reactome.org/PathwayBrowser/#/R-GGA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8981637 https://reactome.org/PathwayBrowser/#/R-GGA-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-8985594 https://reactome.org/PathwayBrowser/#/R-GGA-8985594 MYO9B inactivates RHOA IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-9008822 https://reactome.org/PathwayBrowser/#/R-GGA-9008822 PPM1D dephosphorylates RUNX2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9013022 https://reactome.org/PathwayBrowser/#/R-GGA-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9013111 https://reactome.org/PathwayBrowser/#/R-GGA-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9013144 https://reactome.org/PathwayBrowser/#/R-GGA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9013161 https://reactome.org/PathwayBrowser/#/R-GGA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9013437 https://reactome.org/PathwayBrowser/#/R-GGA-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9014295 https://reactome.org/PathwayBrowser/#/R-GGA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9014434 https://reactome.org/PathwayBrowser/#/R-GGA-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9014641 https://reactome.org/PathwayBrowser/#/R-GGA-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9017488 https://reactome.org/PathwayBrowser/#/R-GGA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018745 https://reactome.org/PathwayBrowser/#/R-GGA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018806 https://reactome.org/PathwayBrowser/#/R-GGA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018814 https://reactome.org/PathwayBrowser/#/R-GGA-9018814 RHOT1 hydrolyzes GTP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018826 https://reactome.org/PathwayBrowser/#/R-GGA-9018826 RHOT2 hydrolyzes GTP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018862 https://reactome.org/PathwayBrowser/#/R-GGA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018868 https://reactome.org/PathwayBrowser/#/R-GGA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018877 https://reactome.org/PathwayBrowser/#/R-GGA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9018895 https://reactome.org/PathwayBrowser/#/R-GGA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020252 https://reactome.org/PathwayBrowser/#/R-GGA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020253 https://reactome.org/PathwayBrowser/#/R-GGA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020257 https://reactome.org/PathwayBrowser/#/R-GGA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020258 https://reactome.org/PathwayBrowser/#/R-GGA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020270 https://reactome.org/PathwayBrowser/#/R-GGA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020271 https://reactome.org/PathwayBrowser/#/R-GGA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9020273 https://reactome.org/PathwayBrowser/#/R-GGA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9024890 https://reactome.org/PathwayBrowser/#/R-GGA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9024993 https://reactome.org/PathwayBrowser/#/R-GGA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9033491 https://reactome.org/PathwayBrowser/#/R-GGA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Gallus gallus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-GGA-9033520 https://reactome.org/PathwayBrowser/#/R-GGA-9033520 TYSND1 cleaves TYSND1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-936802 https://reactome.org/PathwayBrowser/#/R-GGA-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-936883 https://reactome.org/PathwayBrowser/#/R-GGA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-936895 https://reactome.org/PathwayBrowser/#/R-GGA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-936897 https://reactome.org/PathwayBrowser/#/R-GGA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-939763 https://reactome.org/PathwayBrowser/#/R-GGA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-947531 https://reactome.org/PathwayBrowser/#/R-GGA-947531 Molybdenum ion transfer onto molybdopterin IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-947535 https://reactome.org/PathwayBrowser/#/R-GGA-947535 Cyclisation of GTP to precursor Z IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-947591 https://reactome.org/PathwayBrowser/#/R-GGA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9624893 https://reactome.org/PathwayBrowser/#/R-GGA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9629675 https://reactome.org/PathwayBrowser/#/R-GGA-9629675 PDE3A hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9638075 https://reactome.org/PathwayBrowser/#/R-GGA-9638075 HEXB cleaves the terminal GalNAc from DS IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9638076 https://reactome.org/PathwayBrowser/#/R-GGA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9638078 https://reactome.org/PathwayBrowser/#/R-GGA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9638120 https://reactome.org/PathwayBrowser/#/R-GGA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9644869 https://reactome.org/PathwayBrowser/#/R-GGA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9647994 https://reactome.org/PathwayBrowser/#/R-GGA-9647994 RAS proteins are depalmitoylated IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9656893 https://reactome.org/PathwayBrowser/#/R-GGA-9656893 OPN1MW binds 11cRAL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9658445 https://reactome.org/PathwayBrowser/#/R-GGA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9659680 https://reactome.org/PathwayBrowser/#/R-GGA-9659680 ABCB1 transports xenobiotics out of the cell IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9667952 https://reactome.org/PathwayBrowser/#/R-GGA-9667952 ANKLE2 is deacetylated by SIRT2 IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-9673053 https://reactome.org/PathwayBrowser/#/R-GGA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-9673054 https://reactome.org/PathwayBrowser/#/R-GGA-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9674127 https://reactome.org/PathwayBrowser/#/R-GGA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9693282 https://reactome.org/PathwayBrowser/#/R-GGA-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9700200 https://reactome.org/PathwayBrowser/#/R-GGA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-9701565 https://reactome.org/PathwayBrowser/#/R-GGA-9701565 HDACs deacetylate p-STAT3 dimers IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9705507 https://reactome.org/PathwayBrowser/#/R-GGA-9705507 PDE3B hydrolyses cAMP to AMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9706399 https://reactome.org/PathwayBrowser/#/R-GGA-9706399 RHOBTB3 hydrolyzes ATP IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9727567 https://reactome.org/PathwayBrowser/#/R-GGA-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9750546 https://reactome.org/PathwayBrowser/#/R-GGA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9750555 https://reactome.org/PathwayBrowser/#/R-GGA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9750617 https://reactome.org/PathwayBrowser/#/R-GGA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9750656 https://reactome.org/PathwayBrowser/#/R-GGA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9750942 https://reactome.org/PathwayBrowser/#/R-GGA-9750942 USP14 deubiquitinates NLRC5 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753278 https://reactome.org/PathwayBrowser/#/R-GGA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753280 https://reactome.org/PathwayBrowser/#/R-GGA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753283 https://reactome.org/PathwayBrowser/#/R-GGA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753284 https://reactome.org/PathwayBrowser/#/R-GGA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753632 https://reactome.org/PathwayBrowser/#/R-GGA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753634 https://reactome.org/PathwayBrowser/#/R-GGA-9753634 GGT dimers hydrolyse APAP-SG IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9753944 https://reactome.org/PathwayBrowser/#/R-GGA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9754964 https://reactome.org/PathwayBrowser/#/R-GGA-9754964 ADA deamidates RBV IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9755030 https://reactome.org/PathwayBrowser/#/R-GGA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9755078 https://reactome.org/PathwayBrowser/#/R-GGA-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-975593 https://reactome.org/PathwayBrowser/#/R-GGA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-GGA-975594 https://reactome.org/PathwayBrowser/#/R-GGA-975594 PLB1 hydrolyses RPALM to atROL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9759206 https://reactome.org/PathwayBrowser/#/R-GGA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9759454 https://reactome.org/PathwayBrowser/#/R-GGA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9759461 https://reactome.org/PathwayBrowser/#/R-GGA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-977324 https://reactome.org/PathwayBrowser/#/R-GGA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-9825772 https://reactome.org/PathwayBrowser/#/R-GGA-9825772 SIRT1 deacetylates HINT1 dimer IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-983422 https://reactome.org/PathwayBrowser/#/R-GGA-983422 Disassembly of COPII coated vesicle IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9837419 https://reactome.org/PathwayBrowser/#/R-GGA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9838004 https://reactome.org/PathwayBrowser/#/R-GGA-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9838081 https://reactome.org/PathwayBrowser/#/R-GGA-9838081 LONP1 degrades mitochondrial matrix proteins IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9839059 https://reactome.org/PathwayBrowser/#/R-GGA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9839105 https://reactome.org/PathwayBrowser/#/R-GGA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9839113 https://reactome.org/PathwayBrowser/#/R-GGA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9840949 https://reactome.org/PathwayBrowser/#/R-GGA-9840949 ARSA removes sulfate from SM3 IEA Gallus gallus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-GGA-9841189 https://reactome.org/PathwayBrowser/#/R-GGA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9841847 https://reactome.org/PathwayBrowser/#/R-GGA-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9853385 https://reactome.org/PathwayBrowser/#/R-GGA-9853385 PPP1CC dephosphorylates PLK1 IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9861626 https://reactome.org/PathwayBrowser/#/R-GGA-9861626 SIRT4 cleaves lipoyl from DLAT IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9861725 https://reactome.org/PathwayBrowser/#/R-GGA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9865167 https://reactome.org/PathwayBrowser/#/R-GGA-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9865226 https://reactome.org/PathwayBrowser/#/R-GGA-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9912636 https://reactome.org/PathwayBrowser/#/R-GGA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9915968 https://reactome.org/PathwayBrowser/#/R-GGA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9915986 https://reactome.org/PathwayBrowser/#/R-GGA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9915994 https://reactome.org/PathwayBrowser/#/R-GGA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-GGA-9929439 https://reactome.org/PathwayBrowser/#/R-GGA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-997309 https://reactome.org/PathwayBrowser/#/R-GGA-997309 Dephosphorylation of STAT1 by SHP2 IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-997311 https://reactome.org/PathwayBrowser/#/R-GGA-997311 Dephosphorylation of TYK2 by PTP1B IEA Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-GGA-997314 https://reactome.org/PathwayBrowser/#/R-GGA-997314 Dephosphorylation of JAK1 by SHP1 IEA Gallus gallus 15377 R-ALL-113518 H2O [nucleoplasm] R-GGA-997326 https://reactome.org/PathwayBrowser/#/R-GGA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Gallus gallus 15377 R-ALL-109276 H2O [extracellular region] R-HSA-109278 https://reactome.org/PathwayBrowser/#/R-HSA-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-109291 https://reactome.org/PathwayBrowser/#/R-HSA-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109380 https://reactome.org/PathwayBrowser/#/R-HSA-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109387 https://reactome.org/PathwayBrowser/#/R-HSA-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109415 https://reactome.org/PathwayBrowser/#/R-HSA-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109449 https://reactome.org/PathwayBrowser/#/R-HSA-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109470 https://reactome.org/PathwayBrowser/#/R-HSA-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-109480 https://reactome.org/PathwayBrowser/#/R-HSA-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-109514 https://reactome.org/PathwayBrowser/#/R-HSA-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111742 https://reactome.org/PathwayBrowser/#/R-HSA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111751 https://reactome.org/PathwayBrowser/#/R-HSA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111804 https://reactome.org/PathwayBrowser/#/R-HSA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111879 https://reactome.org/PathwayBrowser/#/R-HSA-111879 PIP2 hydrolysis TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111955 https://reactome.org/PathwayBrowser/#/R-HSA-111955 cAMP hydrolysis by Cam-PDE 1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-111962 https://reactome.org/PathwayBrowser/#/R-HSA-111962 PDE4A,C,D hydrolyse cAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-112037 https://reactome.org/PathwayBrowser/#/R-HSA-112037 Inactivation of PLC beta TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-113503 https://reactome.org/PathwayBrowser/#/R-HSA-113503 PP2A mediated localization of RB1 protein in chromatin TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1169192 https://reactome.org/PathwayBrowser/#/R-HSA-1169192 PTP1B dephosphorylates GHR TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1169210 https://reactome.org/PathwayBrowser/#/R-HSA-1169210 PTP1B dephosphorylates JAK2 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1183128 https://reactome.org/PathwayBrowser/#/R-HSA-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222346 https://reactome.org/PathwayBrowser/#/R-HSA-1222346 AhpC reduces H2O2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222431 https://reactome.org/PathwayBrowser/#/R-HSA-1222431 Peroxynitrite is reduced to nitrite by AhpC TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222526 https://reactome.org/PathwayBrowser/#/R-HSA-1222526 AhpC reduces peroxidated lipids TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1222755 https://reactome.org/PathwayBrowser/#/R-HSA-1222755 Peroxynitrite is reduced to nitrite by Tpx TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1236949 https://reactome.org/PathwayBrowser/#/R-HSA-1236949 Translocation of antigenic peptides back to phagosomes via TAP IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1237129 https://reactome.org/PathwayBrowser/#/R-HSA-1237129 Acireductone is created TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1237140 https://reactome.org/PathwayBrowser/#/R-HSA-1237140 Dehydration of methylthio-ribulose-P IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1247910 https://reactome.org/PathwayBrowser/#/R-HSA-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1247935 https://reactome.org/PathwayBrowser/#/R-HSA-1247935 OPLAH hydrolyses OPRO to L-Glu TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1299476 https://reactome.org/PathwayBrowser/#/R-HSA-1299476 MPP cleaves targeting peptide (presequence) of inner membrane precursors IEA Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1299478 https://reactome.org/PathwayBrowser/#/R-HSA-1299478 MPP cleaves targeting peptide (presequence) of matrix precursors IEA Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-1363274 https://reactome.org/PathwayBrowser/#/R-HSA-1363274 Dephosphorylation of p107 (RBL1) by PP2A TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-1363276 https://reactome.org/PathwayBrowser/#/R-HSA-1363276 Dephosphorylation of p130 (RBL2) by PP2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1369028 https://reactome.org/PathwayBrowser/#/R-HSA-1369028 ABCAs mediate lipid efflux TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1369052 https://reactome.org/PathwayBrowser/#/R-HSA-1369052 ABCAs mediate lipid influx TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1369065 https://reactome.org/PathwayBrowser/#/R-HSA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-139906 https://reactome.org/PathwayBrowser/#/R-HSA-139906 Activation of BAD by calcineurin TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-140359 https://reactome.org/PathwayBrowser/#/R-HSA-140359 PGG2 is reduced to PGH2 by PTGS1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-141673 https://reactome.org/PathwayBrowser/#/R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1454916 https://reactome.org/PathwayBrowser/#/R-HSA-1454916 The ABCC family mediates organic anion transport TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1454928 https://reactome.org/PathwayBrowser/#/R-HSA-1454928 ABCG4 may mediate cholesterol efflux TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1467457 https://reactome.org/PathwayBrowser/#/R-HSA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1467466 https://reactome.org/PathwayBrowser/#/R-HSA-1467466 ABCA4 mediates atRAL transport TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1474146 https://reactome.org/PathwayBrowser/#/R-HSA-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482543 https://reactome.org/PathwayBrowser/#/R-HSA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482545 https://reactome.org/PathwayBrowser/#/R-HSA-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482571 https://reactome.org/PathwayBrowser/#/R-HSA-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482604 https://reactome.org/PathwayBrowser/#/R-HSA-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482612 https://reactome.org/PathwayBrowser/#/R-HSA-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482629 https://reactome.org/PathwayBrowser/#/R-HSA-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482656 https://reactome.org/PathwayBrowser/#/R-HSA-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482679 https://reactome.org/PathwayBrowser/#/R-HSA-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482685 https://reactome.org/PathwayBrowser/#/R-HSA-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482696 https://reactome.org/PathwayBrowser/#/R-HSA-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1482745 https://reactome.org/PathwayBrowser/#/R-HSA-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1482759 https://reactome.org/PathwayBrowser/#/R-HSA-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482771 https://reactome.org/PathwayBrowser/#/R-HSA-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482776 https://reactome.org/PathwayBrowser/#/R-HSA-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482777 https://reactome.org/PathwayBrowser/#/R-HSA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1482778 https://reactome.org/PathwayBrowser/#/R-HSA-1482778 CL is hydrolyzed to MLCL by PLA2G6 (IM) IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482811 https://reactome.org/PathwayBrowser/#/R-HSA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482816 https://reactome.org/PathwayBrowser/#/R-HSA-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482825 https://reactome.org/PathwayBrowser/#/R-HSA-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482827 https://reactome.org/PathwayBrowser/#/R-HSA-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482828 https://reactome.org/PathwayBrowser/#/R-HSA-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1482847 https://reactome.org/PathwayBrowser/#/R-HSA-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482856 https://reactome.org/PathwayBrowser/#/R-HSA-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482862 https://reactome.org/PathwayBrowser/#/R-HSA-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482868 https://reactome.org/PathwayBrowser/#/R-HSA-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482884 https://reactome.org/PathwayBrowser/#/R-HSA-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482887 https://reactome.org/PathwayBrowser/#/R-HSA-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482892 https://reactome.org/PathwayBrowser/#/R-HSA-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482897 https://reactome.org/PathwayBrowser/#/R-HSA-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482900 https://reactome.org/PathwayBrowser/#/R-HSA-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482907 https://reactome.org/PathwayBrowser/#/R-HSA-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482920 https://reactome.org/PathwayBrowser/#/R-HSA-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1482932 https://reactome.org/PathwayBrowser/#/R-HSA-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483096 https://reactome.org/PathwayBrowser/#/R-HSA-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483107 https://reactome.org/PathwayBrowser/#/R-HSA-1483107 GPETA is hydrolyzed to ETA and G3P by GPCPD1 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483116 https://reactome.org/PathwayBrowser/#/R-HSA-1483116 GPCho is hydrolyzed to Cho and G3P by GPCPD1 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483159 https://reactome.org/PathwayBrowser/#/R-HSA-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483182 https://reactome.org/PathwayBrowser/#/R-HSA-1483182 PC is hydrolyzed to PA and choline by PLD1/2 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1483197 https://reactome.org/PathwayBrowser/#/R-HSA-1483197 PTPMT1 dephosphorylates PGP to PG IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1483203 https://reactome.org/PathwayBrowser/#/R-HSA-1483203 PA is dephosphorylated to DAG by LPIN TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1500761 https://reactome.org/PathwayBrowser/#/R-HSA-1500761 Nitrogen dioxide is reduced to NO by F420 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1500804 https://reactome.org/PathwayBrowser/#/R-HSA-1500804 Peroxynitrite is reduced by AhpE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-159425 https://reactome.org/PathwayBrowser/#/R-HSA-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602368 https://reactome.org/PathwayBrowser/#/R-HSA-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602374 https://reactome.org/PathwayBrowser/#/R-HSA-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602377 https://reactome.org/PathwayBrowser/#/R-HSA-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602398 https://reactome.org/PathwayBrowser/#/R-HSA-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602399 https://reactome.org/PathwayBrowser/#/R-HSA-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602417 https://reactome.org/PathwayBrowser/#/R-HSA-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-1602446 https://reactome.org/PathwayBrowser/#/R-HSA-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605591 https://reactome.org/PathwayBrowser/#/R-HSA-1605591 GBA1:SAPC hydrolyzes GlcCer TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605595 https://reactome.org/PathwayBrowser/#/R-HSA-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605624 https://reactome.org/PathwayBrowser/#/R-HSA-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605632 https://reactome.org/PathwayBrowser/#/R-HSA-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1605723 https://reactome.org/PathwayBrowser/#/R-HSA-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605724 https://reactome.org/PathwayBrowser/#/R-HSA-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605736 https://reactome.org/PathwayBrowser/#/R-HSA-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1605768 https://reactome.org/PathwayBrowser/#/R-HSA-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1606312 https://reactome.org/PathwayBrowser/#/R-HSA-1606312 GLB1 hydrolyzes SapB/C:LacCer TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1606564 https://reactome.org/PathwayBrowser/#/R-HSA-1606564 GALC hydrolyzes GalCer TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1606583 https://reactome.org/PathwayBrowser/#/R-HSA-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1606602 https://reactome.org/PathwayBrowser/#/R-HSA-1606602 ASAH1 hydrolyzes ceramide TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1606789 https://reactome.org/PathwayBrowser/#/R-HSA-1606789 ARSB hydrolyses DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-1606839 https://reactome.org/PathwayBrowser/#/R-HSA-1606839 ARSC hydrolyzes steroid sulfates TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1614524 https://reactome.org/PathwayBrowser/#/R-HSA-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1614583 https://reactome.org/PathwayBrowser/#/R-HSA-1614583 PXLP-K212-CTH cleaves L-Cystathionine TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to pyruvate and H2S TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-162425 https://reactome.org/PathwayBrowser/#/R-HSA-162425 p-S295-PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-162729 https://reactome.org/PathwayBrowser/#/R-HSA-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-162857 https://reactome.org/PathwayBrowser/#/R-HSA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1630304 https://reactome.org/PathwayBrowser/#/R-HSA-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1630306 https://reactome.org/PathwayBrowser/#/R-HSA-1630306 GLB1 hydrolyses a glycosaminoglycan TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163402 https://reactome.org/PathwayBrowser/#/R-HSA-163402 diacylglycerol + H2O -> 2-acylglycerol + fatty acid IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163432 https://reactome.org/PathwayBrowser/#/R-HSA-163432 cholesterol ester + H2O -> cholesterol + fatty acid IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163489 https://reactome.org/PathwayBrowser/#/R-HSA-163489 phosphorylated HSL + H2O -> HSL + orthophosphate IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163551 https://reactome.org/PathwayBrowser/#/R-HSA-163551 triacylglycerol + H2O -> diacylglycerol + fatty acid IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163568 https://reactome.org/PathwayBrowser/#/R-HSA-163568 phosphorylated perilipin + H2O -> perilipin + orthophosphate IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163595 https://reactome.org/PathwayBrowser/#/R-HSA-163595 2-acylglycerol + H2O -> glycerol + fatty acid IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-163750 https://reactome.org/PathwayBrowser/#/R-HSA-163750 PP2A complex dephosphorylates p-PFKFB1 IEA Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1638032 https://reactome.org/PathwayBrowser/#/R-HSA-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1638053 https://reactome.org/PathwayBrowser/#/R-HSA-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1638821 https://reactome.org/PathwayBrowser/#/R-HSA-1638821 PP2A-B56 dephosphorylates centromeric cohesin TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-164832 https://reactome.org/PathwayBrowser/#/R-HSA-164832 ATPase synthesizes ATP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1667005 https://reactome.org/PathwayBrowser/#/R-HSA-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675795 https://reactome.org/PathwayBrowser/#/R-HSA-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675824 https://reactome.org/PathwayBrowser/#/R-HSA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675836 https://reactome.org/PathwayBrowser/#/R-HSA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675949 https://reactome.org/PathwayBrowser/#/R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675988 https://reactome.org/PathwayBrowser/#/R-HSA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1675994 https://reactome.org/PathwayBrowser/#/R-HSA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676005 https://reactome.org/PathwayBrowser/#/R-HSA-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676020 https://reactome.org/PathwayBrowser/#/R-HSA-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676065 https://reactome.org/PathwayBrowser/#/R-HSA-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676105 https://reactome.org/PathwayBrowser/#/R-HSA-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676114 https://reactome.org/PathwayBrowser/#/R-HSA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676124 https://reactome.org/PathwayBrowser/#/R-HSA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676141 https://reactome.org/PathwayBrowser/#/R-HSA-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676149 https://reactome.org/PathwayBrowser/#/R-HSA-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676162 https://reactome.org/PathwayBrowser/#/R-HSA-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676164 https://reactome.org/PathwayBrowser/#/R-HSA-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676174 https://reactome.org/PathwayBrowser/#/R-HSA-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676177 https://reactome.org/PathwayBrowser/#/R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676203 https://reactome.org/PathwayBrowser/#/R-HSA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1676204 https://reactome.org/PathwayBrowser/#/R-HSA-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-167686 https://reactome.org/PathwayBrowser/#/R-HSA-167686 Active PLCG1 hydrolyses PIP2 IEA Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1678650 https://reactome.org/PathwayBrowser/#/R-HSA-1678650 IDS hydrolyses Heparan sulfate chain(5) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1678708 https://reactome.org/PathwayBrowser/#/R-HSA-1678708 SGSH hydrolyses Heparan sulfate chain(2) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1678716 https://reactome.org/PathwayBrowser/#/R-HSA-1678716 IDUA hydrolyses Heparan sulfate chain(1) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1678742 https://reactome.org/PathwayBrowser/#/R-HSA-1678742 NAGLU hydrolyses Heparan sulfate chain(4) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1678854 https://reactome.org/PathwayBrowser/#/R-HSA-1678854 GUSB tetramer hydrolyses CS/HS precursor TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-170153 https://reactome.org/PathwayBrowser/#/R-HSA-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-170158 https://reactome.org/PathwayBrowser/#/R-HSA-170158 CDC25A dephosphorylates CCNA:CDK1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-170161 https://reactome.org/PathwayBrowser/#/R-HSA-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-173739 https://reactome.org/PathwayBrowser/#/R-HSA-173739 Spontaneous hydrolysis of C3 thioester TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-174110 https://reactome.org/PathwayBrowser/#/R-HSA-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-174124 https://reactome.org/PathwayBrowser/#/R-HSA-174124 Dephosphorylation of phospho-Cdh1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-174391 https://reactome.org/PathwayBrowser/#/R-HSA-174391 MAT1A multimers transfer Ado from ATP to L-Met TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-174401 https://reactome.org/PathwayBrowser/#/R-HSA-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-174439 https://reactome.org/PathwayBrowser/#/R-HSA-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-176606 https://reactome.org/PathwayBrowser/#/R-HSA-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-177501 https://reactome.org/PathwayBrowser/#/R-HSA-177501 Endocytosis (internalization) of clathrin-coated vesicle IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-177923 https://reactome.org/PathwayBrowser/#/R-HSA-177923 Sustained activation of SRC kinase by SHP2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-177924 https://reactome.org/PathwayBrowser/#/R-HSA-177924 Dephosphorylation of Gab1 by SHP2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-177926 https://reactome.org/PathwayBrowser/#/R-HSA-177926 Dephosphorylation of PAG by SHP2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-177935 https://reactome.org/PathwayBrowser/#/R-HSA-177935 SHP2 dephosphorylates Tyr 992 on EGFR TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-178178 https://reactome.org/PathwayBrowser/#/R-HSA-178178 PP1 dephosphorylates TGFBR1 IEA Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793176 https://reactome.org/PathwayBrowser/#/R-HSA-1793176 DS is cleaved from its proteoglycan TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793182 https://reactome.org/PathwayBrowser/#/R-HSA-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793186 https://reactome.org/PathwayBrowser/#/R-HSA-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793207 https://reactome.org/PathwayBrowser/#/R-HSA-1793207 ARSB hydrolyses C4S/C6S chains TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793209 https://reactome.org/PathwayBrowser/#/R-HSA-1793209 HYAL1 hydrolyses Chondroitin chains TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-1793217 https://reactome.org/PathwayBrowser/#/R-HSA-1793217 Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-180632 https://reactome.org/PathwayBrowser/#/R-HSA-180632 Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855154 https://reactome.org/PathwayBrowser/#/R-HSA-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855159 https://reactome.org/PathwayBrowser/#/R-HSA-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-1855163 https://reactome.org/PathwayBrowser/#/R-HSA-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855165 https://reactome.org/PathwayBrowser/#/R-HSA-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855166 https://reactome.org/PathwayBrowser/#/R-HSA-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855171 https://reactome.org/PathwayBrowser/#/R-HSA-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855174 https://reactome.org/PathwayBrowser/#/R-HSA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855177 https://reactome.org/PathwayBrowser/#/R-HSA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855180 https://reactome.org/PathwayBrowser/#/R-HSA-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855198 https://reactome.org/PathwayBrowser/#/R-HSA-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-1855200 https://reactome.org/PathwayBrowser/#/R-HSA-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855202 https://reactome.org/PathwayBrowser/#/R-HSA-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855205 https://reactome.org/PathwayBrowser/#/R-HSA-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855208 https://reactome.org/PathwayBrowser/#/R-HSA-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855210 https://reactome.org/PathwayBrowser/#/R-HSA-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855211 https://reactome.org/PathwayBrowser/#/R-HSA-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855213 https://reactome.org/PathwayBrowser/#/R-HSA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855214 https://reactome.org/PathwayBrowser/#/R-HSA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855218 https://reactome.org/PathwayBrowser/#/R-HSA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855219 https://reactome.org/PathwayBrowser/#/R-HSA-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855221 https://reactome.org/PathwayBrowser/#/R-HSA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855222 https://reactome.org/PathwayBrowser/#/R-HSA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-1855225 https://reactome.org/PathwayBrowser/#/R-HSA-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1855232 https://reactome.org/PathwayBrowser/#/R-HSA-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1861788 https://reactome.org/PathwayBrowser/#/R-HSA-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-1861789 https://reactome.org/PathwayBrowser/#/R-HSA-1861789 GBA3 hydrolyzes GlcCer (cytosol) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-188979 https://reactome.org/PathwayBrowser/#/R-HSA-188979 Digestion of linear starch (amylose) by extracellular amylase TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-188985 https://reactome.org/PathwayBrowser/#/R-HSA-188985 trehalose + H2O => 2 D-glucose IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-189053 https://reactome.org/PathwayBrowser/#/R-HSA-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-189062 https://reactome.org/PathwayBrowser/#/R-HSA-189062 lactose + H2O => D-glucose + D-galactose TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-189069 https://reactome.org/PathwayBrowser/#/R-HSA-189069 sucrose + H2O => glucose + fructose TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-189102 https://reactome.org/PathwayBrowser/#/R-HSA-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-189406 https://reactome.org/PathwayBrowser/#/R-HSA-189406 4 PBGs bind to form HMB TAS Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-189488 https://reactome.org/PathwayBrowser/#/R-HSA-189488 UROS transforms HMB to URO3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-190168 https://reactome.org/PathwayBrowser/#/R-HSA-190168 HMBL spontaneously transforms to URO1 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-191101 https://reactome.org/PathwayBrowser/#/R-HSA-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-191108 https://reactome.org/PathwayBrowser/#/R-HSA-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-191114 https://reactome.org/PathwayBrowser/#/R-HSA-191114 Digestion of branched starch (amylopectin) by extracellular amylase TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-191116 https://reactome.org/PathwayBrowser/#/R-HSA-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-192331 https://reactome.org/PathwayBrowser/#/R-HSA-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192417 https://reactome.org/PathwayBrowser/#/R-HSA-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192422 https://reactome.org/PathwayBrowser/#/R-HSA-192422 Digestion of triacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192425 https://reactome.org/PathwayBrowser/#/R-HSA-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192430 https://reactome.org/PathwayBrowser/#/R-HSA-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192434 https://reactome.org/PathwayBrowser/#/R-HSA-192434 Digestion of diacylglycerols by extracellular PTL:colipase TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-192475 https://reactome.org/PathwayBrowser/#/R-HSA-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193362 https://reactome.org/PathwayBrowser/#/R-HSA-193362 ABCB11 transports bile salts from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-193385 https://reactome.org/PathwayBrowser/#/R-HSA-193385 Hydrolysis of choloyl-CoA to cholate and CoASH TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-193535 https://reactome.org/PathwayBrowser/#/R-HSA-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193706 https://reactome.org/PathwayBrowser/#/R-HSA-193706 Production of ceramide which can activate JNK and other targets IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193711 https://reactome.org/PathwayBrowser/#/R-HSA-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193727 https://reactome.org/PathwayBrowser/#/R-HSA-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193743 https://reactome.org/PathwayBrowser/#/R-HSA-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193766 https://reactome.org/PathwayBrowser/#/R-HSA-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-196950 https://reactome.org/PathwayBrowser/#/R-HSA-196950 2xTRAP hydrolyzes FMN to RIB TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-197186 https://reactome.org/PathwayBrowser/#/R-HSA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-197187 https://reactome.org/PathwayBrowser/#/R-HSA-197187 ACS transforms to QUIN non-enzymatically TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-199425 https://reactome.org/PathwayBrowser/#/R-HSA-199425 PHLPP dephosphorylates S473 in AKT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-199456 https://reactome.org/PathwayBrowser/#/R-HSA-199456 PTEN dephosphorylates PIP3 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-199959 https://reactome.org/PathwayBrowser/#/R-HSA-199959 ERKs are inactivated by protein phosphatase 2A TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-200661 https://reactome.org/PathwayBrowser/#/R-HSA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-200740 https://reactome.org/PathwayBrowser/#/R-HSA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-201035 https://reactome.org/PathwayBrowser/#/R-HSA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-201787 https://reactome.org/PathwayBrowser/#/R-HSA-201787 PPP3 complex dephosphorylates DARPP-32 on Thr34 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-201790 https://reactome.org/PathwayBrowser/#/R-HSA-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-202214 https://reactome.org/PathwayBrowser/#/R-HSA-202214 Dephosphorylation of Lck-pY505 by CD45 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022368 https://reactome.org/PathwayBrowser/#/R-HSA-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-202237 https://reactome.org/PathwayBrowser/#/R-HSA-202237 Hydrolysis of PIP3 to PI(3,4)P2 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022378 https://reactome.org/PathwayBrowser/#/R-HSA-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022379 https://reactome.org/PathwayBrowser/#/R-HSA-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022381 https://reactome.org/PathwayBrowser/#/R-HSA-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022383 https://reactome.org/PathwayBrowser/#/R-HSA-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022393 https://reactome.org/PathwayBrowser/#/R-HSA-2022393 ANPEP:Zn2+ hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8) IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022396 https://reactome.org/PathwayBrowser/#/R-HSA-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022398 https://reactome.org/PathwayBrowser/#/R-HSA-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022399 https://reactome.org/PathwayBrowser/#/R-HSA-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022403 https://reactome.org/PathwayBrowser/#/R-HSA-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022405 https://reactome.org/PathwayBrowser/#/R-HSA-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022411 https://reactome.org/PathwayBrowser/#/R-HSA-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2022412 https://reactome.org/PathwayBrowser/#/R-HSA-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-ALL-2022884 H2O [Golgi lumen] R-HSA-2022887 https://reactome.org/PathwayBrowser/#/R-HSA-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2023971 https://reactome.org/PathwayBrowser/#/R-HSA-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2023973 https://reactome.org/PathwayBrowser/#/R-HSA-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-202407 https://reactome.org/PathwayBrowser/#/R-HSA-202407 PLC-gamma1 hydrolyses PIP2 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2028294 https://reactome.org/PathwayBrowser/#/R-HSA-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2029468 https://reactome.org/PathwayBrowser/#/R-HSA-2029468 Conversion of PA into DAG by PAP-1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2029471 https://reactome.org/PathwayBrowser/#/R-HSA-2029471 Hydrolysis of PC to PA by PLD TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2029475 https://reactome.org/PathwayBrowser/#/R-HSA-2029475 Production of AA by iPLA2 upon FCGR activation TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 Depalmitoylation of eNOS TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-203797 https://reactome.org/PathwayBrowser/#/R-HSA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-204169 https://reactome.org/PathwayBrowser/#/R-HSA-204169 PDP1,2 dephosphorylate p-lipo-PDH TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046083 https://reactome.org/PathwayBrowser/#/R-HSA-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046088 https://reactome.org/PathwayBrowser/#/R-HSA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046090 https://reactome.org/PathwayBrowser/#/R-HSA-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046094 https://reactome.org/PathwayBrowser/#/R-HSA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046095 https://reactome.org/PathwayBrowser/#/R-HSA-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2046100 https://reactome.org/PathwayBrowser/#/R-HSA-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2065233 https://reactome.org/PathwayBrowser/#/R-HSA-2065233 CS is cleaved from its proteoglycan TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2065355 https://reactome.org/PathwayBrowser/#/R-HSA-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2065357 https://reactome.org/PathwayBrowser/#/R-HSA-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-2066778 https://reactome.org/PathwayBrowser/#/R-HSA-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-2066779 https://reactome.org/PathwayBrowser/#/R-HSA-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2090037 https://reactome.org/PathwayBrowser/#/R-HSA-2090037 IDUA hydrolyses Heparan sulfate chain(6) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2090038 https://reactome.org/PathwayBrowser/#/R-HSA-2090038 NAGLU hydrolyses heparan chain(2) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2090043 https://reactome.org/PathwayBrowser/#/R-HSA-2090043 SGSH hydrolyses Heparan sulfate chain(7) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2090079 https://reactome.org/PathwayBrowser/#/R-HSA-2090079 GLB1 hydrolyses linker chain(2) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-209055 https://reactome.org/PathwayBrowser/#/R-HSA-209055 PPM1A dephosphorylates nuclear SMAD2/3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2105001 https://reactome.org/PathwayBrowser/#/R-HSA-2105001 HEXA cleaves the terminal GalNAc from DS TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2130725 https://reactome.org/PathwayBrowser/#/R-HSA-2130725 Internalization of MHC II:Ii clathrin coated vesicle TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2160874 https://reactome.org/PathwayBrowser/#/R-HSA-2160874 HYAL1 hydrolyses (HA)50 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161195 https://reactome.org/PathwayBrowser/#/R-HSA-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161506 https://reactome.org/PathwayBrowser/#/R-HSA-2161506 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161538 https://reactome.org/PathwayBrowser/#/R-HSA-2161538 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161588 https://reactome.org/PathwayBrowser/#/R-HSA-2161588 Delta12-PGJ2 is dehydrated to 15d-PGJ2 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161619 https://reactome.org/PathwayBrowser/#/R-HSA-2161619 PGI2 is hydrolysed to 6k-PGF1a TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161659 https://reactome.org/PathwayBrowser/#/R-HSA-2161659 PGE2 is dehydrated to PGA2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161668 https://reactome.org/PathwayBrowser/#/R-HSA-2161668 PGA2 is dehydrated to 15d-PGA2 IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161673 https://reactome.org/PathwayBrowser/#/R-HSA-2161673 PGD2 is dehydrated to 15d-PGD2 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161733 https://reactome.org/PathwayBrowser/#/R-HSA-2161733 PGD2 is dehydrated to PGJ2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161791 https://reactome.org/PathwayBrowser/#/R-HSA-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161868 https://reactome.org/PathwayBrowser/#/R-HSA-2161868 EXD4 is converted to EXE4 by DPEP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161946 https://reactome.org/PathwayBrowser/#/R-HSA-2161946 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161949 https://reactome.org/PathwayBrowser/#/R-HSA-2161949 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161959 https://reactome.org/PathwayBrowser/#/R-HSA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161961 https://reactome.org/PathwayBrowser/#/R-HSA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161962 https://reactome.org/PathwayBrowser/#/R-HSA-2161962 LTA4 is hydrolysed to 6t-/6t,12epi-LTB4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2161999 https://reactome.org/PathwayBrowser/#/R-HSA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2162225 https://reactome.org/PathwayBrowser/#/R-HSA-2162225 HEXA cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2162226 https://reactome.org/PathwayBrowser/#/R-HSA-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2162227 https://reactome.org/PathwayBrowser/#/R-HSA-2162227 GUSB tetramer hydrolyses (HA)2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-216723 https://reactome.org/PathwayBrowser/#/R-HSA-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-216757 https://reactome.org/PathwayBrowser/#/R-HSA-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2179291 https://reactome.org/PathwayBrowser/#/R-HSA-2179291 UCHL5, USP15 deubiquitinate TGFBR1 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2187401 https://reactome.org/PathwayBrowser/#/R-HSA-2187401 MTMR4 dephosphorylates SMAD2/3 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2206299 https://reactome.org/PathwayBrowser/#/R-HSA-2206299 Defective IDUA does not hydrolyse Heparan sulfate chain(6) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2262743 https://reactome.org/PathwayBrowser/#/R-HSA-2262743 Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2263444 https://reactome.org/PathwayBrowser/#/R-HSA-2263444 Defective SGSH does not hydrolyse Heparan sulfate chain(7) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2263490 https://reactome.org/PathwayBrowser/#/R-HSA-2263490 Defective GALNS does not hydrolyse sulfate from Gal6S in keratan sulfate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2263495 https://reactome.org/PathwayBrowser/#/R-HSA-2263495 Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2263496 https://reactome.org/PathwayBrowser/#/R-HSA-2263496 Defective NAGLU does not hydrolyse Heparan sulfate chain(4) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2265534 https://reactome.org/PathwayBrowser/#/R-HSA-2265534 Defective GLB1 does not hydrolyse a glycosaminoglycan TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2282889 https://reactome.org/PathwayBrowser/#/R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-2309773 https://reactome.org/PathwayBrowser/#/R-HSA-2309773 PGG2 is reduced to PGH2 by PTGS2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2317387 https://reactome.org/PathwayBrowser/#/R-HSA-2317387 PTEN cancer mutants do not dephosphorylate PIP3 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2318373 https://reactome.org/PathwayBrowser/#/R-HSA-2318373 Defective GUSB does not hydrolyse (HA)2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-2318585 https://reactome.org/PathwayBrowser/#/R-HSA-2318585 Defective HYAL1 does not hydrolyse Chondroitin chains TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2393939 https://reactome.org/PathwayBrowser/#/R-HSA-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2393954 https://reactome.org/PathwayBrowser/#/R-HSA-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2404133 https://reactome.org/PathwayBrowser/#/R-HSA-2404133 A REH hydrolses atREs to atROL and FAs TAS Homo sapiens 15377 R-ALL-2429665 H2O [early endosome] R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408530 https://reactome.org/PathwayBrowser/#/R-HSA-2408530 MeSeH is hydrolysed to H2Se by methylselenol demethylase IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408532 https://reactome.org/PathwayBrowser/#/R-HSA-2408532 AdeSeHCys is hydrolysed to SeHCys by AHCY IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408537 https://reactome.org/PathwayBrowser/#/R-HSA-2408537 Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408539 https://reactome.org/PathwayBrowser/#/R-HSA-2408539 MeSec is hydrolysed to MeSeH by PXLP-K212-CTH IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408543 https://reactome.org/PathwayBrowser/#/R-HSA-2408543 SeCysta is hydrolysed to Sec by PXLP-K212-CTH IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408551 https://reactome.org/PathwayBrowser/#/R-HSA-2408551 SeMet is converted to AdoSeMet by MAT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408555 https://reactome.org/PathwayBrowser/#/R-HSA-2408555 Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2408559 https://reactome.org/PathwayBrowser/#/R-HSA-2408559 SeHCys and Ser are dehydrated into SeCysta by CBS IEA Homo sapiens 15377 R-ALL-2429665 H2O [early endosome] R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2454118 https://reactome.org/PathwayBrowser/#/R-HSA-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2465924 https://reactome.org/PathwayBrowser/#/R-HSA-2465924 OPN1LW binds 11cRAL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2466085 https://reactome.org/PathwayBrowser/#/R-HSA-2466085 at-retinyl is hydrolysed from R* to release atRAL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2466749 https://reactome.org/PathwayBrowser/#/R-HSA-2466749 ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2466764 https://reactome.org/PathwayBrowser/#/R-HSA-2466764 NRPE condenses with atRAL to form A2PE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2466802 https://reactome.org/PathwayBrowser/#/R-HSA-2466802 Defective ABCA4 does not transport NRPE from disc membranes TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2466831 https://reactome.org/PathwayBrowser/#/R-HSA-2466831 A2PE hydrolyses to A2E TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2529015 https://reactome.org/PathwayBrowser/#/R-HSA-2529015 Dephosphorylation of CK2-modified condensin I TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2584246 https://reactome.org/PathwayBrowser/#/R-HSA-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2632521 https://reactome.org/PathwayBrowser/#/R-HSA-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-265783 https://reactome.org/PathwayBrowser/#/R-HSA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-266012 https://reactome.org/PathwayBrowser/#/R-HSA-266012 LTD4 is converted to LTE4 by DPEP1/2 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-266046 https://reactome.org/PathwayBrowser/#/R-HSA-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-266051 https://reactome.org/PathwayBrowser/#/R-HSA-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-266070 https://reactome.org/PathwayBrowser/#/R-HSA-266070 LTC4 is exported from the cytosol by ABCC1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-266072 https://reactome.org/PathwayBrowser/#/R-HSA-266072 LTA4 is hydolysed to LTB4 by LTA4H TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-266082 https://reactome.org/PathwayBrowser/#/R-HSA-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2730847 https://reactome.org/PathwayBrowser/#/R-HSA-2730847 Hydrolysis of PIP2 by PLCG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2730849 https://reactome.org/PathwayBrowser/#/R-HSA-2730849 Calcineurin binds and dephosphorylates NFAT TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-2855047 https://reactome.org/PathwayBrowser/#/R-HSA-2855047 Hydrolysis of internal thioester in C4b TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2995330 https://reactome.org/PathwayBrowser/#/R-HSA-2995330 COX10 transforms heme to heme O TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-2995334 https://reactome.org/PathwayBrowser/#/R-HSA-2995334 COX15 transforms heme O to heme A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-2995388 https://reactome.org/PathwayBrowser/#/R-HSA-2995388 PP2A dephosphorylates BANF1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3002811 https://reactome.org/PathwayBrowser/#/R-HSA-3002811 Myosin phosphatase dephosphorylates PLK1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3095901 https://reactome.org/PathwayBrowser/#/R-HSA-3095901 ABCC1 transports cytosolic RCbl to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3215295 https://reactome.org/PathwayBrowser/#/R-HSA-3215295 USP7 deubiquitinates MDM2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3215310 https://reactome.org/PathwayBrowser/#/R-HSA-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3245943 https://reactome.org/PathwayBrowser/#/R-HSA-3245943 Viral DNA cleavage by TREX1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3247569 https://reactome.org/PathwayBrowser/#/R-HSA-3247569 PADI4 deiminates Histones TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-3262512 https://reactome.org/PathwayBrowser/#/R-HSA-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-3266566 https://reactome.org/PathwayBrowser/#/R-HSA-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-3274540 https://reactome.org/PathwayBrowser/#/R-HSA-3274540 Defective G6PC does not hydrolyze glucose 6-phosphate TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-3282876 https://reactome.org/PathwayBrowser/#/R-HSA-3282876 Defective G6PC3 does not hydrolyze glucose 6-phosphate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-3322995 https://reactome.org/PathwayBrowser/#/R-HSA-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-3323013 https://reactome.org/PathwayBrowser/#/R-HSA-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3341277 https://reactome.org/PathwayBrowser/#/R-HSA-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-3341296 https://reactome.org/PathwayBrowser/#/R-HSA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3341343 https://reactome.org/PathwayBrowser/#/R-HSA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-3341397 https://reactome.org/PathwayBrowser/#/R-HSA-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3343700 https://reactome.org/PathwayBrowser/#/R-HSA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3371467 https://reactome.org/PathwayBrowser/#/R-HSA-3371467 SIRT1 deacetylates HSF1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-350604 https://reactome.org/PathwayBrowser/#/R-HSA-350604 Agmatine + H2O <=> putrescine + urea TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3640872 https://reactome.org/PathwayBrowser/#/R-HSA-3640872 USP34 deubiquitinates AXIN1,AXIN2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-3656259 https://reactome.org/PathwayBrowser/#/R-HSA-3656259 Defective HEXA does not cleave the terminal GalNAc from DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-3662344 https://reactome.org/PathwayBrowser/#/R-HSA-3662344 Defective HEXB does not cleave the terminal GalNAc from DS TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3697838 https://reactome.org/PathwayBrowser/#/R-HSA-3697838 ATP7A transfers Cu from ATOX1 to SOD3 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3697882 https://reactome.org/PathwayBrowser/#/R-HSA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-3697894 https://reactome.org/PathwayBrowser/#/R-HSA-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-372519 https://reactome.org/PathwayBrowser/#/R-HSA-372519 AcCho is hydrolyzed to Cho and acetate by ACHE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3769447 https://reactome.org/PathwayBrowser/#/R-HSA-3769447 HDAC1:2-containing complex deacetylate histones TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-377643 https://reactome.org/PathwayBrowser/#/R-HSA-377643 Dephosphorylation of inactive SRC by PTPB1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3777129 https://reactome.org/PathwayBrowser/#/R-HSA-3777129 HDAC3 containing complexes deacetylate histone TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3781011 https://reactome.org/PathwayBrowser/#/R-HSA-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3781018 https://reactome.org/PathwayBrowser/#/R-HSA-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3782637 https://reactome.org/PathwayBrowser/#/R-HSA-3782637 HDAC8 deacetylates histones TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-3782655 https://reactome.org/PathwayBrowser/#/R-HSA-3782655 HDAC10 deacetylates histone TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-3791349 https://reactome.org/PathwayBrowser/#/R-HSA-3791349 Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-380949 https://reactome.org/PathwayBrowser/#/R-HSA-380949 AMPK is dephosphorylated TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-382553 https://reactome.org/PathwayBrowser/#/R-HSA-382553 ABCA7:Apo1A-mediated phospholipid efflux TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-382560 https://reactome.org/PathwayBrowser/#/R-HSA-382560 ABC7, mABC1 and mABC2 mediate heme transport TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-382575 https://reactome.org/PathwayBrowser/#/R-HSA-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-383190 https://reactome.org/PathwayBrowser/#/R-HSA-383190 HCO3- transport through ion channel TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-389580 https://reactome.org/PathwayBrowser/#/R-HSA-389580 formyl-CoA + H2O => formate + CoASH TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-389986 https://reactome.org/PathwayBrowser/#/R-HSA-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-390252 https://reactome.org/PathwayBrowser/#/R-HSA-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-390329 https://reactome.org/PathwayBrowser/#/R-HSA-390329 Dephosphorylation of AKT by PP2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-390393 https://reactome.org/PathwayBrowser/#/R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-399998 https://reactome.org/PathwayBrowser/#/R-HSA-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4084976 https://reactome.org/PathwayBrowser/#/R-HSA-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4084989 https://reactome.org/PathwayBrowser/#/R-HSA-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4084994 https://reactome.org/PathwayBrowser/#/R-HSA-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-4084999 https://reactome.org/PathwayBrowser/#/R-HSA-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4085021 https://reactome.org/PathwayBrowser/#/R-HSA-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4085029 https://reactome.org/PathwayBrowser/#/R-HSA-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4086392 https://reactome.org/PathwayBrowser/#/R-HSA-4086392 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-4088141 https://reactome.org/PathwayBrowser/#/R-HSA-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4088338 https://reactome.org/PathwayBrowser/#/R-HSA-4088338 Defective GNE does not hydrolyse UDP-GlcNAc TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4093339 https://reactome.org/PathwayBrowser/#/R-HSA-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-416559 https://reactome.org/PathwayBrowser/#/R-HSA-416559 Inactivation of Rho-GTP by p190RhoGAP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-418553 https://reactome.org/PathwayBrowser/#/R-HSA-418553 cAMP degradation by Phosphodiesterases TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-419232 https://reactome.org/PathwayBrowser/#/R-HSA-419232 Myosin phosphatase dephosphorylates myosin regulatory light chain IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428205 https://reactome.org/PathwayBrowser/#/R-HSA-428205 ACER2 hydrolyzes ceramide (Golgi) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428231 https://reactome.org/PathwayBrowser/#/R-HSA-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428262 https://reactome.org/PathwayBrowser/#/R-HSA-428262 ACER3 hydrolyzes phytoceramide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428522 https://reactome.org/PathwayBrowser/#/R-HSA-428522 Inactivation of RAC1 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428533 https://reactome.org/PathwayBrowser/#/R-HSA-428533 Inactivation of CDC42 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428664 https://reactome.org/PathwayBrowser/#/R-HSA-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-428690 https://reactome.org/PathwayBrowser/#/R-HSA-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-428696 https://reactome.org/PathwayBrowser/#/R-HSA-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429730 https://reactome.org/PathwayBrowser/#/R-HSA-429730 PPM1L dephosphorylates multiphospho-CERT1-2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429845 https://reactome.org/PathwayBrowser/#/R-HSA-429845 5' to 3' exoribonuclease hydrolyzes decapped mRNA IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429860 https://reactome.org/PathwayBrowser/#/R-HSA-429860 DCP1-DCP2 complex decaps mRNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429955 https://reactome.org/PathwayBrowser/#/R-HSA-429955 CCR4-NOT complex deadenylates mRNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429961 https://reactome.org/PathwayBrowser/#/R-HSA-429961 DCPS scavenges the 7-methylguanosine cap of mRNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-429992 https://reactome.org/PathwayBrowser/#/R-HSA-429992 PARN deadenylates mRNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-430021 https://reactome.org/PathwayBrowser/#/R-HSA-430021 PAN2-PAN3 complex partially deadenylates mRNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-430028 https://reactome.org/PathwayBrowser/#/R-HSA-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-432010 https://reactome.org/PathwayBrowser/#/R-HSA-432010 Aquaporin-1 passively transports water into cell TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-432010 https://reactome.org/PathwayBrowser/#/R-HSA-432010 Aquaporin-1 passively transports water into cell TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-432054 https://reactome.org/PathwayBrowser/#/R-HSA-432054 Aquaporin-1 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-432054 https://reactome.org/PathwayBrowser/#/R-HSA-432054 Aquaporin-1 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-432065 https://reactome.org/PathwayBrowser/#/R-HSA-432065 p-S256-Aquaporin-2 passively transports water into cell TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-432065 https://reactome.org/PathwayBrowser/#/R-HSA-432065 p-S256-Aquaporin-2 passively transports water into cell TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-432067 https://reactome.org/PathwayBrowser/#/R-HSA-432067 Aquaporin-4 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-432067 https://reactome.org/PathwayBrowser/#/R-HSA-432067 Aquaporin-4 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-4341669 https://reactome.org/PathwayBrowser/#/R-HSA-4341669 Defective NEU1 does not hydrolyse Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-4419948 https://reactome.org/PathwayBrowser/#/R-HSA-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4419986 https://reactome.org/PathwayBrowser/#/R-HSA-4419986 Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-443894 https://reactome.org/PathwayBrowser/#/R-HSA-443894 TXA2 is hydrolysed to TXB2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-445714 https://reactome.org/PathwayBrowser/#/R-HSA-445714 Aquaporin-3 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-445714 https://reactome.org/PathwayBrowser/#/R-HSA-445714 Aquaporin-3 passively transports water out of cell TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-449937 https://reactome.org/PathwayBrowser/#/R-HSA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-452036 https://reactome.org/PathwayBrowser/#/R-HSA-452036 arginine + H2O => ornithine + urea [ARG2] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4551451 https://reactome.org/PathwayBrowser/#/R-HSA-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-4641236 https://reactome.org/PathwayBrowser/#/R-HSA-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-4793949 https://reactome.org/PathwayBrowser/#/R-HSA-4793949 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-507868 https://reactome.org/PathwayBrowser/#/R-HSA-507868 Aquaporins passively transport water into cells TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-507868 https://reactome.org/PathwayBrowser/#/R-HSA-507868 Aquaporins passively transport water into cells TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-507870 https://reactome.org/PathwayBrowser/#/R-HSA-507870 Aquaporins passively transport water out of cells TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-507870 https://reactome.org/PathwayBrowser/#/R-HSA-507870 Aquaporins passively transport water out of cells TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5221130 https://reactome.org/PathwayBrowser/#/R-HSA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5223313 https://reactome.org/PathwayBrowser/#/R-HSA-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5223317 https://reactome.org/PathwayBrowser/#/R-HSA-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5251955 https://reactome.org/PathwayBrowser/#/R-HSA-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5251959 https://reactome.org/PathwayBrowser/#/R-HSA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5251989 https://reactome.org/PathwayBrowser/#/R-HSA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5333609 https://reactome.org/PathwayBrowser/#/R-HSA-5333609 MeSebGalNac is hydrolysed to MeSeH and bGalNac IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5333615 https://reactome.org/PathwayBrowser/#/R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5362459 https://reactome.org/PathwayBrowser/#/R-HSA-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5387389 https://reactome.org/PathwayBrowser/#/R-HSA-5387389 Hh processing variants are translocated to the cytosol in a VCP-dependent manner TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423656 https://reactome.org/PathwayBrowser/#/R-HSA-5423656 AFXBO hydrolyses non-enzymatically to AFBDHD TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5423694 https://reactome.org/PathwayBrowser/#/R-HSA-5423694 AFBDHD hydrolyses non-enzymatically to AFBDHO TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5433072 https://reactome.org/PathwayBrowser/#/R-HSA-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5433074 https://reactome.org/PathwayBrowser/#/R-HSA-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-548843 https://reactome.org/PathwayBrowser/#/R-HSA-548843 ACSL3,4 ligate CoA to AA to form AA-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5579081 https://reactome.org/PathwayBrowser/#/R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5579084 https://reactome.org/PathwayBrowser/#/R-HSA-5579084 Defective AHCY does not hydrolyse AdoHcy TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5602984 https://reactome.org/PathwayBrowser/#/R-HSA-5602984 Defective GGT1 does not hydrolyse glutamate from AFXBO-SG, AFNBO-SG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5603087 https://reactome.org/PathwayBrowser/#/R-HSA-5603087 Defective MAT1A does not transfer Ado from ATP to L-Met TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5603114 https://reactome.org/PathwayBrowser/#/R-HSA-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5603208 https://reactome.org/PathwayBrowser/#/R-HSA-5603208 Defective OPLAH does not hydrolyse OPRO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5607735 https://reactome.org/PathwayBrowser/#/R-HSA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5618093 https://reactome.org/PathwayBrowser/#/R-HSA-5618093 ATP hydrolysis by HSP90 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5623513 https://reactome.org/PathwayBrowser/#/R-HSA-5623513 ASAP1 stimulates GTPase activity of ARF4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5628905 https://reactome.org/PathwayBrowser/#/R-HSA-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5631885 https://reactome.org/PathwayBrowser/#/R-HSA-5631885 PRDX1 overoxidizes TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5649705 https://reactome.org/PathwayBrowser/#/R-HSA-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5651828 https://reactome.org/PathwayBrowser/#/R-HSA-5651828 PARG dePARylates PARP1,PARP2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5653770 https://reactome.org/PathwayBrowser/#/R-HSA-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5653786 https://reactome.org/PathwayBrowser/#/R-HSA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5655955 https://reactome.org/PathwayBrowser/#/R-HSA-5655955 OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5658001 https://reactome.org/PathwayBrowser/#/R-HSA-5658001 Defective LCT does not hydrolyze Lac TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5659861 https://reactome.org/PathwayBrowser/#/R-HSA-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5659879 https://reactome.org/PathwayBrowser/#/R-HSA-5659879 Defective SI does not hydrolyze iMal IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5659899 https://reactome.org/PathwayBrowser/#/R-HSA-5659899 Defective SI does not hydrolyze maltotriose IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5659922 https://reactome.org/PathwayBrowser/#/R-HSA-5659922 Defective SI does not hydrolyze Mal TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5659926 https://reactome.org/PathwayBrowser/#/R-HSA-5659926 Defective SI does not hydrolyze Suc IEA Homo sapiens 15377 R-ALL-5668574 H2O [melanosome lumen] R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5665809 https://reactome.org/PathwayBrowser/#/R-HSA-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5672957 https://reactome.org/PathwayBrowser/#/R-HSA-5672957 PP2A dephosphorylates KSR1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5672961 https://reactome.org/PathwayBrowser/#/R-HSA-5672961 PP2A dephosphorylates inactive RAFs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5675373 https://reactome.org/PathwayBrowser/#/R-HSA-5675373 Nuclear DUSPs dephosphorylate MAPKs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5675376 https://reactome.org/PathwayBrowser/#/R-HSA-5675376 Cytosolic DUSPs dephosphorylate MAPKs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5675431 https://reactome.org/PathwayBrowser/#/R-HSA-5675431 PP2A dephosphorylates RAF1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5675433 https://reactome.org/PathwayBrowser/#/R-HSA-5675433 PP5 dephosphorylates RAF1 S338 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5676637 https://reactome.org/PathwayBrowser/#/R-HSA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5676912 https://reactome.org/PathwayBrowser/#/R-HSA-5676912 Methionine is oxidised to methionine sulfoxide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5676926 https://reactome.org/PathwayBrowser/#/R-HSA-5676926 Methionine sulfoxide is oxidised to methionine sulfone TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678517 https://reactome.org/PathwayBrowser/#/R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678706 https://reactome.org/PathwayBrowser/#/R-HSA-5678706 ABCB4 transports PC from plasma membrane to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678749 https://reactome.org/PathwayBrowser/#/R-HSA-5678749 Defective ABCB4 does not transport PC from plasma membrane to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678822 https://reactome.org/PathwayBrowser/#/R-HSA-5678822 Defective CFTR does not transport Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678863 https://reactome.org/PathwayBrowser/#/R-HSA-5678863 CFTR transports Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5678992 https://reactome.org/PathwayBrowser/#/R-HSA-5678992 Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5679031 https://reactome.org/PathwayBrowser/#/R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5679041 https://reactome.org/PathwayBrowser/#/R-HSA-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5679101 https://reactome.org/PathwayBrowser/#/R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5679145 https://reactome.org/PathwayBrowser/#/R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5682111 https://reactome.org/PathwayBrowser/#/R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5682285 https://reactome.org/PathwayBrowser/#/R-HSA-5682285 ABCA12 transports lipids from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5682311 https://reactome.org/PathwayBrowser/#/R-HSA-5682311 Defective ABCA12 does not transport lipids from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5683325 https://reactome.org/PathwayBrowser/#/R-HSA-5683325 Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5683355 https://reactome.org/PathwayBrowser/#/R-HSA-5683355 Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5683405 https://reactome.org/PathwayBrowser/#/R-HSA-5683405 PPP5C dephosphorylates TP53BP1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5683672 https://reactome.org/PathwayBrowser/#/R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5683714 https://reactome.org/PathwayBrowser/#/R-HSA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5683967 https://reactome.org/PathwayBrowser/#/R-HSA-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5684043 https://reactome.org/PathwayBrowser/#/R-HSA-5684043 Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix TAS Homo sapiens 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-HSA-5684864 https://reactome.org/PathwayBrowser/#/R-HSA-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB TAS Homo sapiens 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-HSA-5685902 https://reactome.org/PathwayBrowser/#/R-HSA-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5685994 https://reactome.org/PathwayBrowser/#/R-HSA-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5686410 https://reactome.org/PathwayBrowser/#/R-HSA-5686410 BLM mediates dissolution of double Holliday junction TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5687464 https://reactome.org/PathwayBrowser/#/R-HSA-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5687664 https://reactome.org/PathwayBrowser/#/R-HSA-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5687758 https://reactome.org/PathwayBrowser/#/R-HSA-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5688397 https://reactome.org/PathwayBrowser/#/R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5688797 https://reactome.org/PathwayBrowser/#/R-HSA-5688797 ATXN3 family cleave Ub chains TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5688837 https://reactome.org/PathwayBrowser/#/R-HSA-5688837 ATXN3 deubiquitinates polyUb-PARK2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5689000 https://reactome.org/PathwayBrowser/#/R-HSA-5689000 AADAC deacetylates PHEN TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5689950 https://reactome.org/PathwayBrowser/#/R-HSA-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5689972 https://reactome.org/PathwayBrowser/#/R-HSA-5689972 USP2 deubiquitinates MDM2,MDM4 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5689973 https://reactome.org/PathwayBrowser/#/R-HSA-5689973 USP10,USP24,USP42 deubiquitinate TP53 TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690043 https://reactome.org/PathwayBrowser/#/R-HSA-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5690066 https://reactome.org/PathwayBrowser/#/R-HSA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5690080 https://reactome.org/PathwayBrowser/#/R-HSA-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690152 https://reactome.org/PathwayBrowser/#/R-HSA-5690152 USP5 cleaves polyubiquitin TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5690157 https://reactome.org/PathwayBrowser/#/R-HSA-5690157 USP16,USP21 deubiquitinate Histone H2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690159 https://reactome.org/PathwayBrowser/#/R-HSA-5690159 USP21 deubiquitinates RIPK1,DDX58 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690196 https://reactome.org/PathwayBrowser/#/R-HSA-5690196 USP8 deubiquitinates RNF128 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690319 https://reactome.org/PathwayBrowser/#/R-HSA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690340 https://reactome.org/PathwayBrowser/#/R-HSA-5690340 Defective ABCC6 does not transport organic anion from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-5690517 https://reactome.org/PathwayBrowser/#/R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5690759 https://reactome.org/PathwayBrowser/#/R-HSA-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5690790 https://reactome.org/PathwayBrowser/#/R-HSA-5690790 Histone H2A is dubiquitinated by the PR-DUB complex TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690808 https://reactome.org/PathwayBrowser/#/R-HSA-5690808 UCHL3, SENP8 cleave NEDD8 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690856 https://reactome.org/PathwayBrowser/#/R-HSA-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5690870 https://reactome.org/PathwayBrowser/#/R-HSA-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5691381 https://reactome.org/PathwayBrowser/#/R-HSA-5691381 MYSM1 deubiquitinates Histone H2A TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5691411 https://reactome.org/PathwayBrowser/#/R-HSA-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5691439 https://reactome.org/PathwayBrowser/#/R-HSA-5691439 BRISC complex deubiquitinates NLRP3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5691507 https://reactome.org/PathwayBrowser/#/R-HSA-5691507 ASPA deacetylates NAASP to acetate and L-aspartate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5691512 https://reactome.org/PathwayBrowser/#/R-HSA-5691512 APEH hydrolyses NAc-Ser-protein TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5692462 https://reactome.org/PathwayBrowser/#/R-HSA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5692480 https://reactome.org/PathwayBrowser/#/R-HSA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5692754 https://reactome.org/PathwayBrowser/#/R-HSA-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 TAS Homo sapiens 15377 R-ALL-2022884 H2O [Golgi lumen] R-HSA-5693092 https://reactome.org/PathwayBrowser/#/R-HSA-5693092 Unknown deacetylase deacetylates 7K-BACE1(46-501) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5693153 https://reactome.org/PathwayBrowser/#/R-HSA-5693153 PPM1K dephosphorylates p-BCKDH TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5693346 https://reactome.org/PathwayBrowser/#/R-HSA-5693346 CECRI deaminates Ade-Rib to Ino TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5693373 https://reactome.org/PathwayBrowser/#/R-HSA-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5693589 https://reactome.org/PathwayBrowser/#/R-HSA-5693589 D-loop dissociation and strand annealing TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5693608 https://reactome.org/PathwayBrowser/#/R-HSA-5693608 Initial resection of double-strand break ends TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-5693724 https://reactome.org/PathwayBrowser/#/R-HSA-5693724 ESD dimer hydrolyses S-FGSH to GSH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5693742 https://reactome.org/PathwayBrowser/#/R-HSA-5693742 FAAH hydrolyses AEA to AA and ETA TAS Homo sapiens 15377 R-ALL-5693747 H2O [lipid droplet] R-HSA-5693751 https://reactome.org/PathwayBrowser/#/R-HSA-5693751 FAAH2 hydrolyses AEA to AA and ETA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5693783 https://reactome.org/PathwayBrowser/#/R-HSA-5693783 NAALADases hydrolyse NAAG TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-5693807 https://reactome.org/PathwayBrowser/#/R-HSA-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694077 https://reactome.org/PathwayBrowser/#/R-HSA-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5694109 https://reactome.org/PathwayBrowser/#/R-HSA-5694109 LIPC dimer hydrolyses TAG to DAG and FA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694126 https://reactome.org/PathwayBrowser/#/R-HSA-5694126 NT5C3B hydrolyses 7MGP to 7MG TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5694137 https://reactome.org/PathwayBrowser/#/R-HSA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694421 https://reactome.org/PathwayBrowser/#/R-HSA-5694421 PP6 dephosphorylates SEC24 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694485 https://reactome.org/PathwayBrowser/#/R-HSA-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5694563 https://reactome.org/PathwayBrowser/#/R-HSA-5694563 ABHD10 hydrolyses MPAG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5694583 https://reactome.org/PathwayBrowser/#/R-HSA-5694583 ABHD4 hydrolyses NAPE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5695964 https://reactome.org/PathwayBrowser/#/R-HSA-5695964 ABHD14B hydrolyses PNPB TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696049 https://reactome.org/PathwayBrowser/#/R-HSA-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5696197 https://reactome.org/PathwayBrowser/#/R-HSA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696230 https://reactome.org/PathwayBrowser/#/R-HSA-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696365 https://reactome.org/PathwayBrowser/#/R-HSA-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5696408 https://reactome.org/PathwayBrowser/#/R-HSA-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-5696415 https://reactome.org/PathwayBrowser/#/R-HSA-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696465 https://reactome.org/PathwayBrowser/#/R-HSA-5696465 USP45 deubiquitinates ERCC1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696534 https://reactome.org/PathwayBrowser/#/R-HSA-5696534 USP18 deubiquitinates TAK1:TAB1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696564 https://reactome.org/PathwayBrowser/#/R-HSA-5696564 USP25 deubiquitinates DDX58 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696600 https://reactome.org/PathwayBrowser/#/R-HSA-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696605 https://reactome.org/PathwayBrowser/#/R-HSA-5696605 USP12, USP26 deubiquitinate AR TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696627 https://reactome.org/PathwayBrowser/#/R-HSA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696872 https://reactome.org/PathwayBrowser/#/R-HSA-5696872 USP30 deubiquitinates Ub-MOM proteins TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696914 https://reactome.org/PathwayBrowser/#/R-HSA-5696914 USP28 deubiquitinates CLSPN and MYC TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696945 https://reactome.org/PathwayBrowser/#/R-HSA-5696945 USP33 deubiquitinates CCP110,ARRB TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696947 https://reactome.org/PathwayBrowser/#/R-HSA-5696947 USP47 deubiquitinates POLB TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696958 https://reactome.org/PathwayBrowser/#/R-HSA-5696958 USP44 deubiquitinates CDC20 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696960 https://reactome.org/PathwayBrowser/#/R-HSA-5696960 USP49 deubiquitinates H2B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-5696968 https://reactome.org/PathwayBrowser/#/R-HSA-5696968 USP20, USP33 deubiquitinate ADRB2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5696997 https://reactome.org/PathwayBrowser/#/R-HSA-5696997 USP24 deubiquitinates DDB2 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-5697009 https://reactome.org/PathwayBrowser/#/R-HSA-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-622382 https://reactome.org/PathwayBrowser/#/R-HSA-622382 PIP2 hydrolysis IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6781764 https://reactome.org/PathwayBrowser/#/R-HSA-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6781779 https://reactome.org/PathwayBrowser/#/R-HSA-6781779 USP13 deubiquitinates BECN1,USP10 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6781814 https://reactome.org/PathwayBrowser/#/R-HSA-6781814 USP19 deubiquitinates RNF123 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6781897 https://reactome.org/PathwayBrowser/#/R-HSA-6781897 USP11 deubiquitinates NFKBIA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6782069 https://reactome.org/PathwayBrowser/#/R-HSA-6782069 UVSSA:USP7 deubiquitinates ERCC6 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6782106 https://reactome.org/PathwayBrowser/#/R-HSA-6782106 USP10 deubiquitinates SNX3, CFTR TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6782311 https://reactome.org/PathwayBrowser/#/R-HSA-6782311 ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6782336 https://reactome.org/PathwayBrowser/#/R-HSA-6782336 ADAT1 deaminates adenosine-37 in tRNA(Ala) IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6782628 https://reactome.org/PathwayBrowser/#/R-HSA-6782628 USP8 deubiquitinates STAM2:HGS TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-6782685 https://reactome.org/PathwayBrowser/#/R-HSA-6782685 EDEM1,3 hydrolyse (GlcNAc)2 (Man)8b to (GlcNAc)2 (Man)5 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6782820 https://reactome.org/PathwayBrowser/#/R-HSA-6782820 USP17 deubiquitinates SUDS3 TAS Homo sapiens 15377 R-ALL-5278291 H2O [cytoplasm] R-HSA-6782895 https://reactome.org/PathwayBrowser/#/R-HSA-6782895 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) IEA Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6783177 https://reactome.org/PathwayBrowser/#/R-HSA-6783177 USP21 deubiquitinates GATA3,IL33 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6783883 https://reactome.org/PathwayBrowser/#/R-HSA-6783883 P6C transforms to 2AMAS TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6784402 https://reactome.org/PathwayBrowser/#/R-HSA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6784959 https://reactome.org/PathwayBrowser/#/R-HSA-6784959 BPHL hydrolyses VACV to ACV TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6786190 https://reactome.org/PathwayBrowser/#/R-HSA-6786190 CMBL hydrolyses OM to OLMS TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6786421 https://reactome.org/PathwayBrowser/#/R-HSA-6786421 CHIA hydrolyses chitin TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6786650 https://reactome.org/PathwayBrowser/#/R-HSA-6786650 DDHD1,2 hydrolyse PA TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6786652 https://reactome.org/PathwayBrowser/#/R-HSA-6786652 CHIT1 hydrolyses CHIT to 3xADGP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6787632 https://reactome.org/PathwayBrowser/#/R-HSA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6788295 https://reactome.org/PathwayBrowser/#/R-HSA-6788295 HDHD1:Mg2+ dephosphorylates PURIDP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6788912 https://reactome.org/PathwayBrowser/#/R-HSA-6788912 LHPP:Mg2+ dimer hydrolyses PPi TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6789042 https://reactome.org/PathwayBrowser/#/R-HSA-6789042 Hydroxyl-initiated lipid peroxidation TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6789114 https://reactome.org/PathwayBrowser/#/R-HSA-6789114 Hydroxyl radical reacts with the base and sugar moiety of DNA TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6789185 https://reactome.org/PathwayBrowser/#/R-HSA-6789185 Chloride ion and N-acyl group react to chloramide TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6789218 https://reactome.org/PathwayBrowser/#/R-HSA-6789218 Hypochlorous acid (HOCl) reacts with unsaturated lipid to form lipid chlorohydrins TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6789310 https://reactome.org/PathwayBrowser/#/R-HSA-6789310 LIPs hydrolyse TG to DAG and RCOOH TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6792445 https://reactome.org/PathwayBrowser/#/R-HSA-6792445 LIPH, I hydrolyse PA to 2-acyl LPA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6792863 https://reactome.org/PathwayBrowser/#/R-HSA-6792863 PP2A-PP2R5C dephosphorylates MDM2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6797627 https://reactome.org/PathwayBrowser/#/R-HSA-6797627 ASPG hydrolyses L-Asn to L-Asp TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6797630 https://reactome.org/PathwayBrowser/#/R-HSA-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6797653 https://reactome.org/PathwayBrowser/#/R-HSA-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6797913 https://reactome.org/PathwayBrowser/#/R-HSA-6797913 SARDH:FAD oxidatively demethylates SARC to Gly TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6797955 https://reactome.org/PathwayBrowser/#/R-HSA-6797955 ALDH7A1 oxidises BETALD to BET TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6799545 https://reactome.org/PathwayBrowser/#/R-HSA-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-6799581 https://reactome.org/PathwayBrowser/#/R-HSA-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6799604 https://reactome.org/PathwayBrowser/#/R-HSA-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6799695 https://reactome.org/PathwayBrowser/#/R-HSA-6799695 GPX5,6 reduce H2O2 to H2O TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6799977 https://reactome.org/PathwayBrowser/#/R-HSA-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6800198 https://reactome.org/PathwayBrowser/#/R-HSA-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6800200 https://reactome.org/PathwayBrowser/#/R-HSA-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6800299 https://reactome.org/PathwayBrowser/#/R-HSA-6800299 HGFAC cleaves pro-HGF to form HGF dimer TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6801462 https://reactome.org/PathwayBrowser/#/R-HSA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6803545 https://reactome.org/PathwayBrowser/#/R-HSA-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-6803753 https://reactome.org/PathwayBrowser/#/R-HSA-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6803789 https://reactome.org/PathwayBrowser/#/R-HSA-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-6803999 https://reactome.org/PathwayBrowser/#/R-HSA-6803999 HNO2 produces N2O3 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6805650 https://reactome.org/PathwayBrowser/#/R-HSA-6805650 MTA2-NuRD complex deacetylates TP53 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6807008 https://reactome.org/PathwayBrowser/#/R-HSA-6807008 PTPRJ dephosphorylates MET TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6807027 https://reactome.org/PathwayBrowser/#/R-HSA-6807027 PTPN1 and PTPN2 dephosphorylate MET TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6807118 https://reactome.org/PathwayBrowser/#/R-HSA-6807118 USP7 deubiquitinates monoubiquitinated PTEN TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6807206 https://reactome.org/PathwayBrowser/#/R-HSA-6807206 USP13 and OTUD3 deubiquitinate PTEN TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6809263 https://reactome.org/PathwayBrowser/#/R-HSA-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809320 https://reactome.org/PathwayBrowser/#/R-HSA-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809325 https://reactome.org/PathwayBrowser/#/R-HSA-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809561 https://reactome.org/PathwayBrowser/#/R-HSA-6809561 I(1,3)P2 is dephosphorylated into I1P by MTMR7 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809565 https://reactome.org/PathwayBrowser/#/R-HSA-6809565 I(1,3)P2 is dephosphorylated into I1P by MTMR7:MTMR9 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809720 https://reactome.org/PathwayBrowser/#/R-HSA-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809777 https://reactome.org/PathwayBrowser/#/R-HSA-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809778 https://reactome.org/PathwayBrowser/#/R-HSA-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809944 https://reactome.org/PathwayBrowser/#/R-HSA-6809944 PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6809975 https://reactome.org/PathwayBrowser/#/R-HSA-6809975 PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-6810410 https://reactome.org/PathwayBrowser/#/R-HSA-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6810464 https://reactome.org/PathwayBrowser/#/R-HSA-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-6810472 https://reactome.org/PathwayBrowser/#/R-HSA-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6811504 https://reactome.org/PathwayBrowser/#/R-HSA-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6813720 https://reactome.org/PathwayBrowser/#/R-HSA-6813720 NCEH1 hydrolyzes cholesterol esters TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6813740 https://reactome.org/PathwayBrowser/#/R-HSA-6813740 GDE1 hydrolyzes GroPIns TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6814132 https://reactome.org/PathwayBrowser/#/R-HSA-6814132 GDPD5 hydrolyzes GPCho IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6814254 https://reactome.org/PathwayBrowser/#/R-HSA-6814254 PNPLA6 hydrolyzes LysoPtdCho TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6814766 https://reactome.org/PathwayBrowser/#/R-HSA-6814766 GDPD1 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-6814778 https://reactome.org/PathwayBrowser/#/R-HSA-6814778 GDPD3 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-6814797 https://reactome.org/PathwayBrowser/#/R-HSA-6814797 ENPP6 hydrolyzes lysophosphatidylcholine TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-69199 https://reactome.org/PathwayBrowser/#/R-HSA-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70262 https://reactome.org/PathwayBrowser/#/R-HSA-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70479 https://reactome.org/PathwayBrowser/#/R-HSA-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70494 https://reactome.org/PathwayBrowser/#/R-HSA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70569 https://reactome.org/PathwayBrowser/#/R-HSA-70569 arginine + H2O => ornithine + urea [ARG1] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70609 https://reactome.org/PathwayBrowser/#/R-HSA-70609 glutamine + H2O => glutamate + NH4+ (GLS) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70655 https://reactome.org/PathwayBrowser/#/R-HSA-70655 L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70667 https://reactome.org/PathwayBrowser/#/R-HSA-70667 1PYR-5COOH spontaneously hydrolyses to L-GluSS TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70785 https://reactome.org/PathwayBrowser/#/R-HSA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70830 https://reactome.org/PathwayBrowser/#/R-HSA-70830 tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70870 https://reactome.org/PathwayBrowser/#/R-HSA-70870 ECHS1 hydrates methacrylyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70903 https://reactome.org/PathwayBrowser/#/R-HSA-70903 urocanate + H2O => 4-imidazolone-5-propanoate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-70906 https://reactome.org/PathwayBrowser/#/R-HSA-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-70982 https://reactome.org/PathwayBrowser/#/R-HSA-70982 FH tetramer hydrates fumarate to L-malate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71146 https://reactome.org/PathwayBrowser/#/R-HSA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71287 https://reactome.org/PathwayBrowser/#/R-HSA-71287 phosphocreatine + H2O => creatinine + orthophosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71296 https://reactome.org/PathwayBrowser/#/R-HSA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71660 https://reactome.org/PathwayBrowser/#/R-HSA-71660 Enolase dimers dehydrates 2PG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71676 https://reactome.org/PathwayBrowser/#/R-HSA-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-71732 https://reactome.org/PathwayBrowser/#/R-HSA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-71825 https://reactome.org/PathwayBrowser/#/R-HSA-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73608 https://reactome.org/PathwayBrowser/#/R-HSA-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73797 https://reactome.org/PathwayBrowser/#/R-HSA-73797 FAICAR => IMP + H2O TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-73815 https://reactome.org/PathwayBrowser/#/R-HSA-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74059 https://reactome.org/PathwayBrowser/#/R-HSA-74059 PDE6 hydrolyses cGMP to GMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74241 https://reactome.org/PathwayBrowser/#/R-HSA-74241 ADA catalyzes the deamination of (deoxy)adenosine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74248 https://reactome.org/PathwayBrowser/#/R-HSA-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74733 https://reactome.org/PathwayBrowser/#/R-HSA-74733 Insulin receptor de-phosphorylation TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-74948 https://reactome.org/PathwayBrowser/#/R-HSA-74948 PP2A dephosphorylates p-RHO to RHO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-75899 https://reactome.org/PathwayBrowser/#/R-HSA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-76590 https://reactome.org/PathwayBrowser/#/R-HSA-76590 AMP + H2O => IMP + NH4+ (AMPD) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77256 https://reactome.org/PathwayBrowser/#/R-HSA-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77277 https://reactome.org/PathwayBrowser/#/R-HSA-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77301 https://reactome.org/PathwayBrowser/#/R-HSA-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77314 https://reactome.org/PathwayBrowser/#/R-HSA-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77325 https://reactome.org/PathwayBrowser/#/R-HSA-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77333 https://reactome.org/PathwayBrowser/#/R-HSA-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-77344 https://reactome.org/PathwayBrowser/#/R-HSA-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-77614 https://reactome.org/PathwayBrowser/#/R-HSA-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-77615 https://reactome.org/PathwayBrowser/#/R-HSA-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-83677 https://reactome.org/PathwayBrowser/#/R-HSA-83677 C4 deamination of cytidine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-870437 https://reactome.org/PathwayBrowser/#/R-HSA-870437 USP9X (FAM) deubiquitinates SMAD4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-877308 https://reactome.org/PathwayBrowser/#/R-HSA-877308 Dephosphorylation of JAKs by PTPs IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8847912 https://reactome.org/PathwayBrowser/#/R-HSA-8847912 PNPLA7 hydrolyzes LysoPtdCho IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848053 https://reactome.org/PathwayBrowser/#/R-HSA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848215 https://reactome.org/PathwayBrowser/#/R-HSA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848338 https://reactome.org/PathwayBrowser/#/R-HSA-8848338 PNPLA4 hydrolyzes TAG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848339 https://reactome.org/PathwayBrowser/#/R-HSA-8848339 PNPLA5 hydrolyzes TAG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848355 https://reactome.org/PathwayBrowser/#/R-HSA-8848355 PNPLA4 hydrolyzes retinyl palmitate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8848484 https://reactome.org/PathwayBrowser/#/R-HSA-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8849435 https://reactome.org/PathwayBrowser/#/R-HSA-8849435 PTPN1 dephosphorylates PTK6 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8849826 https://reactome.org/PathwayBrowser/#/R-HSA-8849826 ST14 hydrolyzes and activates KLK5 IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8849857 https://reactome.org/PathwayBrowser/#/R-HSA-8849857 KLK5 cleaves and activates CELA2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8849969 https://reactome.org/PathwayBrowser/#/R-HSA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8850594 https://reactome.org/PathwayBrowser/#/R-HSA-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8850831 https://reactome.org/PathwayBrowser/#/R-HSA-8850831 KLK5 cleaves and activates KLK8 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-2022884 H2O [Golgi lumen] R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-2022884 H2O [Golgi lumen] R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8852200 https://reactome.org/PathwayBrowser/#/R-HSA-8852200 Inactivation of LCK by PTPN22 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8853379 https://reactome.org/PathwayBrowser/#/R-HSA-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-8853686 https://reactome.org/PathwayBrowser/#/R-HSA-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8854173 https://reactome.org/PathwayBrowser/#/R-HSA-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8854255 https://reactome.org/PathwayBrowser/#/R-HSA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8854329 https://reactome.org/PathwayBrowser/#/R-HSA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8854604 https://reactome.org/PathwayBrowser/#/R-HSA-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8854612 https://reactome.org/PathwayBrowser/#/R-HSA-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8855381 https://reactome.org/PathwayBrowser/#/R-HSA-8855381 PTPN22 dephosphorylates ZAP70 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8855490 https://reactome.org/PathwayBrowser/#/R-HSA-8855490 Lactoperoxidase (LPO) produces OSCN- TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8855825 https://reactome.org/PathwayBrowser/#/R-HSA-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-8856951 https://reactome.org/PathwayBrowser/#/R-HSA-8856951 PP2A demethylation by PPME1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-8862184 https://reactome.org/PathwayBrowser/#/R-HSA-8862184 USP48 cleaves polyubiquitin TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8862320 https://reactome.org/PathwayBrowser/#/R-HSA-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8863012 https://reactome.org/PathwayBrowser/#/R-HSA-8863012 Calpain cleaves p35 to p25 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8863804 https://reactome.org/PathwayBrowser/#/R-HSA-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8864029 https://reactome.org/PathwayBrowser/#/R-HSA-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8864036 https://reactome.org/PathwayBrowser/#/R-HSA-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8864125 https://reactome.org/PathwayBrowser/#/R-HSA-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-8865667 https://reactome.org/PathwayBrowser/#/R-HSA-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8866105 https://reactome.org/PathwayBrowser/#/R-HSA-8866105 CCPs deglutamylate tubulin IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8866405 https://reactome.org/PathwayBrowser/#/R-HSA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8866542 https://reactome.org/PathwayBrowser/#/R-HSA-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8866854 https://reactome.org/PathwayBrowser/#/R-HSA-8866854 VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8867047 https://reactome.org/PathwayBrowser/#/R-HSA-8867047 PTPN3 dephosphorylates EPS15 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-8867344 https://reactome.org/PathwayBrowser/#/R-HSA-8867344 OMA1 hydrolyses OPA1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8867658 https://reactome.org/PathwayBrowser/#/R-HSA-8867658 PTPN3 dephosphorylates MAPK12 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8868648 https://reactome.org/PathwayBrowser/#/R-HSA-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8868658 https://reactome.org/PathwayBrowser/#/R-HSA-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8868661 https://reactome.org/PathwayBrowser/#/R-HSA-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8869206 https://reactome.org/PathwayBrowser/#/R-HSA-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8869425 https://reactome.org/PathwayBrowser/#/R-HSA-8869425 PLA1A hydrolyses PS to 2-acyl LPS TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8869456 https://reactome.org/PathwayBrowser/#/R-HSA-8869456 USP4 deubiquitinate TRAF2,TRAF6 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8869506 https://reactome.org/PathwayBrowser/#/R-HSA-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8874435 https://reactome.org/PathwayBrowser/#/R-HSA-8874435 THEM86B hydrolyses PMCHO, PMETAM TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8875443 https://reactome.org/PathwayBrowser/#/R-HSA-8875443 USP8 deubiquitinates LRIG1 TAS Homo sapiens 15377 R-ALL-5668574 H2O [melanosome lumen] R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-8878654 https://reactome.org/PathwayBrowser/#/R-HSA-8878654 ACP6 hydrolyses MYS-LPA TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8878787 https://reactome.org/PathwayBrowser/#/R-HSA-8878787 ALPI dimer hydrolyses phosphate monoesters TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8932633 https://reactome.org/PathwayBrowser/#/R-HSA-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8933328 https://reactome.org/PathwayBrowser/#/R-HSA-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-893596 https://reactome.org/PathwayBrowser/#/R-HSA-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-893597 https://reactome.org/PathwayBrowser/#/R-HSA-893597 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [mitochondrial] TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8937442 https://reactome.org/PathwayBrowser/#/R-HSA-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-8937767 https://reactome.org/PathwayBrowser/#/R-HSA-8937767 PTPN11 dephosphorylates RUNX1 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8938314 https://reactome.org/PathwayBrowser/#/R-HSA-8938314 ENPPs hydrolyse CoA-SH to PPANT, PAP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8940074 https://reactome.org/PathwayBrowser/#/R-HSA-8940074 NT5E:Zn2+ hydrolyses NMN TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8940388 https://reactome.org/PathwayBrowser/#/R-HSA-8940388 GPLD1 hydrolyses GPI-anchors from proteins TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8941411 https://reactome.org/PathwayBrowser/#/R-HSA-8941411 OSCN- reacts with Cys residues TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8943279 https://reactome.org/PathwayBrowser/#/R-HSA-8943279 GGT dimers hydrolyse GSH TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-8952069 https://reactome.org/PathwayBrowser/#/R-HSA-8952069 HDAC4 deacetylates RUNX3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8952137 https://reactome.org/PathwayBrowser/#/R-HSA-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8952251 https://reactome.org/PathwayBrowser/#/R-HSA-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-8952903 https://reactome.org/PathwayBrowser/#/R-HSA-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8953339 https://reactome.org/PathwayBrowser/#/R-HSA-8953339 DNPH1 hydrolyses dGMP TAS Homo sapiens 15377 R-ALL-2022884 H2O [Golgi lumen] R-HSA-8953499 https://reactome.org/PathwayBrowser/#/R-HSA-8953499 IMPAD1 hydrolyses PAP to AMP TAS Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-8954398 https://reactome.org/PathwayBrowser/#/R-HSA-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8955712 https://reactome.org/PathwayBrowser/#/R-HSA-8955712 SVBP:VASH1,VASH2 hydrolyzes the terminal L-Tyr residue from alphaY-beta tubulin dimer IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8955794 https://reactome.org/PathwayBrowser/#/R-HSA-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-8955817 https://reactome.org/PathwayBrowser/#/R-HSA-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-8957389 https://reactome.org/PathwayBrowser/#/R-HSA-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8979996 https://reactome.org/PathwayBrowser/#/R-HSA-8979996 LIPs hydrolyze TG to DAG and LCFA TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-8980228 https://reactome.org/PathwayBrowser/#/R-HSA-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8981637 https://reactome.org/PathwayBrowser/#/R-HSA-8981637 RHOA GAPs stimulate RHOA GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8985594 https://reactome.org/PathwayBrowser/#/R-HSA-8985594 MYO9B inactivates RHOA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-8986083 https://reactome.org/PathwayBrowser/#/R-HSA-8986083 USP33 deubiquitinates ROBO1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9008822 https://reactome.org/PathwayBrowser/#/R-HSA-9008822 PPM1D dephosphorylates RUNX2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-901024 https://reactome.org/PathwayBrowser/#/R-HSA-901024 MAN1B1 hydrolyses 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-901036 https://reactome.org/PathwayBrowser/#/R-HSA-901036 MAN1B1 hydrolyses a second 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-901039 https://reactome.org/PathwayBrowser/#/R-HSA-901039 MAN1B1 hydrolyses 1,2-linked mannose (c branch) TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-901074 https://reactome.org/PathwayBrowser/#/R-HSA-901074 MAN1B1,EDEM2 hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-901097 https://reactome.org/PathwayBrowser/#/R-HSA-901097 PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9013022 https://reactome.org/PathwayBrowser/#/R-HSA-9013022 RHOB GAPs stimulate RHOB GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9013111 https://reactome.org/PathwayBrowser/#/R-HSA-9013111 RHOC GAPs stimulate RHOC GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9013144 https://reactome.org/PathwayBrowser/#/R-HSA-9013144 RAC1 GAPs stimulate RAC1 GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9013161 https://reactome.org/PathwayBrowser/#/R-HSA-9013161 CDC42 GAPs stimulate CDC42 GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9013437 https://reactome.org/PathwayBrowser/#/R-HSA-9013437 RHOD GAPs stimulate RHOD GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9014295 https://reactome.org/PathwayBrowser/#/R-HSA-9014295 RAC2 GAPs stimulate RAC2 GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9014434 https://reactome.org/PathwayBrowser/#/R-HSA-9014434 RHOG GAPs stimulate RHOG GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9014641 https://reactome.org/PathwayBrowser/#/R-HSA-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9017488 https://reactome.org/PathwayBrowser/#/R-HSA-9017488 RHOJ GAPs stimulate RHOJ GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018745 https://reactome.org/PathwayBrowser/#/R-HSA-9018745 RHOQ GAPs stimulate RHOQ GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018806 https://reactome.org/PathwayBrowser/#/R-HSA-9018806 RAC3 GAPs stimulate RAC3 GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018814 https://reactome.org/PathwayBrowser/#/R-HSA-9018814 RHOT1 hydrolyzes GTP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018826 https://reactome.org/PathwayBrowser/#/R-HSA-9018826 RHOT2 hydrolyzes GTP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018862 https://reactome.org/PathwayBrowser/#/R-HSA-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018867 https://reactome.org/PathwayBrowser/#/R-HSA-9018867 5-HEDH dehydrogenates 5(S)-Hp-18(S)-HpEPE to 18(S)-RvE2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018868 https://reactome.org/PathwayBrowser/#/R-HSA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018877 https://reactome.org/PathwayBrowser/#/R-HSA-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018895 https://reactome.org/PathwayBrowser/#/R-HSA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9018901 https://reactome.org/PathwayBrowser/#/R-HSA-9018901 5-HEDH dehydrogenates 5(S)-Hp-18(R)-HEPE to 18(R)-RvE2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020252 https://reactome.org/PathwayBrowser/#/R-HSA-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020253 https://reactome.org/PathwayBrowser/#/R-HSA-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020257 https://reactome.org/PathwayBrowser/#/R-HSA-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020258 https://reactome.org/PathwayBrowser/#/R-HSA-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020270 https://reactome.org/PathwayBrowser/#/R-HSA-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020271 https://reactome.org/PathwayBrowser/#/R-HSA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9020273 https://reactome.org/PathwayBrowser/#/R-HSA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA TAS Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-HSA-9023159 https://reactome.org/PathwayBrowser/#/R-HSA-9023159 Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) IEA Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-HSA-9023163 https://reactome.org/PathwayBrowser/#/R-HSA-9023163 Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) IEA Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-HSA-9023178 https://reactome.org/PathwayBrowser/#/R-HSA-9023178 PCSK2 cleaves Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) IEA Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-HSA-9023196 https://reactome.org/PathwayBrowser/#/R-HSA-9023196 PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9024890 https://reactome.org/PathwayBrowser/#/R-HSA-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9024973 https://reactome.org/PathwayBrowser/#/R-HSA-9024973 Epoxide hydrolase hydrolyses 13(S),14(S)-epoxy-DHA to MaR1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9024993 https://reactome.org/PathwayBrowser/#/R-HSA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9025998 https://reactome.org/PathwayBrowser/#/R-HSA-9025998 Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026000 https://reactome.org/PathwayBrowser/#/R-HSA-9026000 Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026008 https://reactome.org/PathwayBrowser/#/R-HSA-9026008 Epoxide hydrolase hydrolyses 7,8-epoxy-HDPAn-3 to RvD1n-3DPA or RvD2n-3DPA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026544 https://reactome.org/PathwayBrowser/#/R-HSA-9026544 Non-enzymatic hydrolysis hydrolyses 13(S),14(S)-epoxy-DHA to 7-epi-MaR1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026757 https://reactome.org/PathwayBrowser/#/R-HSA-9026757 GGT hydrolyses MCTR1 to MCTR2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026771 https://reactome.org/PathwayBrowser/#/R-HSA-9026771 DPEP hydrolyses MCTR2 to MCTR3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026907 https://reactome.org/PathwayBrowser/#/R-HSA-9026907 GGT hydrolyses PCTR2 to PCTR3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026912 https://reactome.org/PathwayBrowser/#/R-HSA-9026912 GGT hydrolyses PCTR1 to PCTR2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026916 https://reactome.org/PathwayBrowser/#/R-HSA-9026916 GGT hydrolyses RCTR2 to RCTR3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9026927 https://reactome.org/PathwayBrowser/#/R-HSA-9026927 GGT hydrolyses RCTR1 to RCTR2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9027670 https://reactome.org/PathwayBrowser/#/R-HSA-9027670 ESTG binding induces ESR depalmitoylation TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9028260 https://reactome.org/PathwayBrowser/#/R-HSA-9028260 δ12-PGJ3 spontaneously dehydrates to 15d-PGJ3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9028273 https://reactome.org/PathwayBrowser/#/R-HSA-9028273 PGH3 spontaneously dehydrates to PGJ3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9032478 https://reactome.org/PathwayBrowser/#/R-HSA-9032478 EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9033478 https://reactome.org/PathwayBrowser/#/R-HSA-9033478 USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033490 https://reactome.org/PathwayBrowser/#/R-HSA-9033490 TYSND1 cleaves PHYH IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9033491 https://reactome.org/PathwayBrowser/#/R-HSA-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033506 https://reactome.org/PathwayBrowser/#/R-HSA-9033506 TYSND1 cleaves AGPS IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033515 https://reactome.org/PathwayBrowser/#/R-HSA-9033515 TYSND1 cleaves ACOX1 IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033520 https://reactome.org/PathwayBrowser/#/R-HSA-9033520 TYSND1 cleaves TYSND1 TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033524 https://reactome.org/PathwayBrowser/#/R-HSA-9033524 TYSND1 cleaves SCP2 IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033529 https://reactome.org/PathwayBrowser/#/R-HSA-9033529 TYSND1 cleaves ACAA1 IEA Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-HSA-9033530 https://reactome.org/PathwayBrowser/#/R-HSA-9033530 TYSND1 cleaves HSD17B4 IEA Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9035966 https://reactome.org/PathwayBrowser/#/R-HSA-9035966 Defective GGT1 does not hydrolyse GSH TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9035976 https://reactome.org/PathwayBrowser/#/R-HSA-9035976 Defective HEXA does not cleave the terminall GalNAc from small HA fragments TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9035978 https://reactome.org/PathwayBrowser/#/R-HSA-9035978 Defective HEXA does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9035982 https://reactome.org/PathwayBrowser/#/R-HSA-9035982 Defective HEXB does not cleave the terminal GalNAc from HA fragments TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9035983 https://reactome.org/PathwayBrowser/#/R-HSA-9035983 Defective HEXB does not cleave the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-9036008 https://reactome.org/PathwayBrowser/#/R-HSA-9036008 Defective MAN1B1 does not hydrolyse a second 1,2-linked mannose (a branch) TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-9036011 https://reactome.org/PathwayBrowser/#/R-HSA-9036011 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (b branch) TAS Homo sapiens 15377 R-ALL-6781870 H2O [endoplasmic reticulum quality control compartment] R-HSA-9036012 https://reactome.org/PathwayBrowser/#/R-HSA-9036012 Defective MAN1B1 does not hydrolyse 1,2-linked mannose (c branch) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036037 https://reactome.org/PathwayBrowser/#/R-HSA-9036037 Defective IDUA does not hydrolyse Heparan sulfate chain(1) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036041 https://reactome.org/PathwayBrowser/#/R-HSA-9036041 Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036046 https://reactome.org/PathwayBrowser/#/R-HSA-9036046 Defective IDS does not hydrolyse Heparan sulfate chain(5) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036050 https://reactome.org/PathwayBrowser/#/R-HSA-9036050 Defective SGSH does not hydrolyse Heparan sulfate chain(2) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036052 https://reactome.org/PathwayBrowser/#/R-HSA-9036052 Defective NAGLU does not hydrolyse heparan chain(2) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036061 https://reactome.org/PathwayBrowser/#/R-HSA-9036061 Defective GLB1 does not hydrolyse linker chain(2) TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036065 https://reactome.org/PathwayBrowser/#/R-HSA-9036065 Defective ARSB does not hydrolyse DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036068 https://reactome.org/PathwayBrowser/#/R-HSA-9036068 Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036070 https://reactome.org/PathwayBrowser/#/R-HSA-9036070 Defective GUSB does not hydrolyse CS/HS precursor TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036077 https://reactome.org/PathwayBrowser/#/R-HSA-9036077 Defective HYAL1 does not hydrolyse (HA)50 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036727 https://reactome.org/PathwayBrowser/#/R-HSA-9036727 GAA hydrolyzes lysosomal glycogen TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9036729 https://reactome.org/PathwayBrowser/#/R-HSA-9036729 Defective GAA does not hydrolyze lysosomal glycogen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-936381 https://reactome.org/PathwayBrowser/#/R-HSA-936381 OTUD5 deubiquitinates TRAF3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-936802 https://reactome.org/PathwayBrowser/#/R-HSA-936802 ATP7A transports cytosolic Cu2+ to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-936883 https://reactome.org/PathwayBrowser/#/R-HSA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-936895 https://reactome.org/PathwayBrowser/#/R-HSA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-936897 https://reactome.org/PathwayBrowser/#/R-HSA-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-939763 https://reactome.org/PathwayBrowser/#/R-HSA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-947531 https://reactome.org/PathwayBrowser/#/R-HSA-947531 Molybdenum ion transfer onto molybdopterin TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-947535 https://reactome.org/PathwayBrowser/#/R-HSA-947535 Cyclisation of GTP to precursor Z TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-947591 https://reactome.org/PathwayBrowser/#/R-HSA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9603719 https://reactome.org/PathwayBrowser/#/R-HSA-9603719 Protein tyrosine phosphatases dephosphorylate NTRK3 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9619430 https://reactome.org/PathwayBrowser/#/R-HSA-9619430 PPM1E dephosphorylates CAMK4 IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9619449 https://reactome.org/PathwayBrowser/#/R-HSA-9619449 PPM1F dephosphorylates p-T286-CaMKII IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9619467 https://reactome.org/PathwayBrowser/#/R-HSA-9619467 PPM1F dephosphorylates CAMK1 IEA Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9624893 https://reactome.org/PathwayBrowser/#/R-HSA-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-9625548 https://reactome.org/PathwayBrowser/#/R-HSA-9625548 Hypochlorous acid (HOCL) oxidizes Cys residues to form Cys-sulfenyl chloride TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-9625904 https://reactome.org/PathwayBrowser/#/R-HSA-9625904 Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-9625913 https://reactome.org/PathwayBrowser/#/R-HSA-9625913 Hypochlorous acid (HOCL) reacts with Lys-monochloramine TAS Homo sapiens 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-HSA-9626753 https://reactome.org/PathwayBrowser/#/R-HSA-9626753 H2O2 oxidizes Cys residues to form Cys-sulfenic acid TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9629675 https://reactome.org/PathwayBrowser/#/R-HSA-9629675 PDE3A hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9635461 https://reactome.org/PathwayBrowser/#/R-HSA-9635461 PtpA dephosphorylates GSK3A TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9635739 https://reactome.org/PathwayBrowser/#/R-HSA-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9636439 https://reactome.org/PathwayBrowser/#/R-HSA-9636439 PtpA:Ub dephosphorylates p-Y133-VPS33B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9636457 https://reactome.org/PathwayBrowser/#/R-HSA-9636457 SapM dephosphorylates PI3P TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9636684 https://reactome.org/PathwayBrowser/#/R-HSA-9636684 NdkA dephosphorylates RAB5A:GTP,RAB7A:GTP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9638046 https://reactome.org/PathwayBrowser/#/R-HSA-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9638075 https://reactome.org/PathwayBrowser/#/R-HSA-9638075 HEXB cleaves the terminal GalNAc from DS TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9638076 https://reactome.org/PathwayBrowser/#/R-HSA-9638076 HEXB cleaves the terminal GalNAc from small HA fragments TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9638078 https://reactome.org/PathwayBrowser/#/R-HSA-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9638120 https://reactome.org/PathwayBrowser/#/R-HSA-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9640307 https://reactome.org/PathwayBrowser/#/R-HSA-9640307 DeHA hydrolyses to 2,3-DKG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9640316 https://reactome.org/PathwayBrowser/#/R-HSA-9640316 DeHA hydrolyses to threonate and oxalate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9644869 https://reactome.org/PathwayBrowser/#/R-HSA-9644869 p-S54-PDE4B hydrolyses cAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9647994 https://reactome.org/PathwayBrowser/#/R-HSA-9647994 RAS proteins are depalmitoylated TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-965067 https://reactome.org/PathwayBrowser/#/R-HSA-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9652816 https://reactome.org/PathwayBrowser/#/R-HSA-9652816 Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9653514 https://reactome.org/PathwayBrowser/#/R-HSA-9653514 USP17L2 deubiquitinates RCE1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9656891 https://reactome.org/PathwayBrowser/#/R-HSA-9656891 OPN1SW binds 11cRAL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9656893 https://reactome.org/PathwayBrowser/#/R-HSA-9656893 OPN1MW binds 11cRAL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9658445 https://reactome.org/PathwayBrowser/#/R-HSA-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9659680 https://reactome.org/PathwayBrowser/#/R-HSA-9659680 ABCB1 transports xenobiotics out of the cell TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9660536 https://reactome.org/PathwayBrowser/#/R-HSA-9660536 SHOC2 M173I disrupts the SHOC2:MRAS:PP1 complex TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9660538 https://reactome.org/PathwayBrowser/#/R-HSA-9660538 Mutant MRAS:SHOC2:PPP1CC complexes dephosphorylate inactive RAFs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9661417 https://reactome.org/PathwayBrowser/#/R-HSA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9661820 https://reactome.org/PathwayBrowser/#/R-HSA-9661820 Bacterial GUSB hydrolyses BDG to BIL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9667952 https://reactome.org/PathwayBrowser/#/R-HSA-9667952 ANKLE2 is deacetylated by SIRT2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9668419 https://reactome.org/PathwayBrowser/#/R-HSA-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9673053 https://reactome.org/PathwayBrowser/#/R-HSA-9673053 PM20D1 transforms oleoyl-phe from oleate and phe TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9673054 https://reactome.org/PathwayBrowser/#/R-HSA-9673054 PM20D1 hydrolyzes oleoyl-phe TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9674127 https://reactome.org/PathwayBrowser/#/R-HSA-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9680388 https://reactome.org/PathwayBrowser/#/R-HSA-9680388 CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9682603 https://reactome.org/PathwayBrowser/#/R-HSA-9682603 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9683663 https://reactome.org/PathwayBrowser/#/R-HSA-9683663 N-glycan trimming of Spike TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684016 https://reactome.org/PathwayBrowser/#/R-HSA-9684016 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 mRNAs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684017 https://reactome.org/PathwayBrowser/#/R-HSA-9684017 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA (plus strand) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684018 https://reactome.org/PathwayBrowser/#/R-HSA-9684018 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-1 gRNA complement (minus strand) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684273 https://reactome.org/PathwayBrowser/#/R-HSA-9684273 3CLp cleaves pp1a TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684309 https://reactome.org/PathwayBrowser/#/R-HSA-9684309 3CLp cleaves nsp6-11 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684321 https://reactome.org/PathwayBrowser/#/R-HSA-9684321 nsp3 cleaves nsp1-4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684336 https://reactome.org/PathwayBrowser/#/R-HSA-9684336 nsp1-4 cleaves itself TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684340 https://reactome.org/PathwayBrowser/#/R-HSA-9684340 3CLp cleaves pp1ab TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684351 https://reactome.org/PathwayBrowser/#/R-HSA-9684351 pp1a cleaves itself TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9684352 https://reactome.org/PathwayBrowser/#/R-HSA-9684352 nsp3-4 cleaves itself TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9686524 https://reactome.org/PathwayBrowser/#/R-HSA-9686524 PP6-PPP6R3 dephosphorylates TERF2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9693282 https://reactome.org/PathwayBrowser/#/R-HSA-9693282 RHOF GAPs stimulate RHOF GTPase activity TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694338 https://reactome.org/PathwayBrowser/#/R-HSA-9694338 nsp1-4 cleaves itself IEA Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9694364 https://reactome.org/PathwayBrowser/#/R-HSA-9694364 N-glycan glucose trimming of Spike TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694377 https://reactome.org/PathwayBrowser/#/R-HSA-9694377 pp1a cleaves itself TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694441 https://reactome.org/PathwayBrowser/#/R-HSA-9694441 3CLp cleaves pp1a TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694476 https://reactome.org/PathwayBrowser/#/R-HSA-9694476 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 mRNAs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694492 https://reactome.org/PathwayBrowser/#/R-HSA-9694492 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694551 https://reactome.org/PathwayBrowser/#/R-HSA-9694551 3CLp cleaves nsp6-11 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694601 https://reactome.org/PathwayBrowser/#/R-HSA-9694601 nsp3-4 cleaves itself IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694625 https://reactome.org/PathwayBrowser/#/R-HSA-9694625 nsp3 cleaves nsp1-4 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694632 https://reactome.org/PathwayBrowser/#/R-HSA-9694632 nsp14 acts as a 3'-to-5' exonuclease to remove misincorporated nucleotides from nascent RNA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694732 https://reactome.org/PathwayBrowser/#/R-HSA-9694732 3CLp cleaves pp1ab TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9694737 https://reactome.org/PathwayBrowser/#/R-HSA-9694737 nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA (plus strand) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9698408 https://reactome.org/PathwayBrowser/#/R-HSA-9698408 PTPRJ dephosphorylates active FLT3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9700200 https://reactome.org/PathwayBrowser/#/R-HSA-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9701507 https://reactome.org/PathwayBrowser/#/R-HSA-9701507 PTPN6 dephosphorylates JAK3 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9701565 https://reactome.org/PathwayBrowser/#/R-HSA-9701565 HDACs deacetylate p-STAT3 dimers TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9705507 https://reactome.org/PathwayBrowser/#/R-HSA-9705507 PDE3B hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9706399 https://reactome.org/PathwayBrowser/#/R-HSA-9706399 RHOBTB3 hydrolyzes ATP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9708261 https://reactome.org/PathwayBrowser/#/R-HSA-9708261 PDE4A hydrolyses cAMP to AMP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9717205 https://reactome.org/PathwayBrowser/#/R-HSA-9717205 GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9727567 https://reactome.org/PathwayBrowser/#/R-HSA-9727567 CES1 hydrolyses sacubitril to sacubitrilat TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9729704 https://reactome.org/PathwayBrowser/#/R-HSA-9729704 SARS-CoV-2 3CLpro dimer cleaves TAB1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9729725 https://reactome.org/PathwayBrowser/#/R-HSA-9729725 SARS-CoV-2 nsp3 deISGylates ISGylated IRF3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9729730 https://reactome.org/PathwayBrowser/#/R-HSA-9729730 SARS-CoV-2 nsp3 cleaves IRF3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9729741 https://reactome.org/PathwayBrowser/#/R-HSA-9729741 SARS-CoV-2 3CLpro dimer cleaves NLRP12 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9734745 https://reactome.org/PathwayBrowser/#/R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9750546 https://reactome.org/PathwayBrowser/#/R-HSA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9750555 https://reactome.org/PathwayBrowser/#/R-HSA-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9750617 https://reactome.org/PathwayBrowser/#/R-HSA-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9750656 https://reactome.org/PathwayBrowser/#/R-HSA-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9750942 https://reactome.org/PathwayBrowser/#/R-HSA-9750942 USP14 deubiquitinates NLRC5 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753278 https://reactome.org/PathwayBrowser/#/R-HSA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753280 https://reactome.org/PathwayBrowser/#/R-HSA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753283 https://reactome.org/PathwayBrowser/#/R-HSA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753284 https://reactome.org/PathwayBrowser/#/R-HSA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753632 https://reactome.org/PathwayBrowser/#/R-HSA-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753634 https://reactome.org/PathwayBrowser/#/R-HSA-9753634 GGT dimers hydrolyse APAP-SG TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9753944 https://reactome.org/PathwayBrowser/#/R-HSA-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9754964 https://reactome.org/PathwayBrowser/#/R-HSA-9754964 ADA deamidates RBV TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9755030 https://reactome.org/PathwayBrowser/#/R-HSA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9755078 https://reactome.org/PathwayBrowser/#/R-HSA-9755078 NT5C2 tetramer dephosphorylates RBV-MP TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9755244 https://reactome.org/PathwayBrowser/#/R-HSA-9755244 SARS-CoV-2 nsp3 deISGylates ISGylated IFIH1 TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-975593 https://reactome.org/PathwayBrowser/#/R-HSA-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-975594 https://reactome.org/PathwayBrowser/#/R-HSA-975594 PLB1 hydrolyses RPALM to atROL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9759206 https://reactome.org/PathwayBrowser/#/R-HSA-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9759454 https://reactome.org/PathwayBrowser/#/R-HSA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9759461 https://reactome.org/PathwayBrowser/#/R-HSA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-977324 https://reactome.org/PathwayBrowser/#/R-HSA-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9794120 https://reactome.org/PathwayBrowser/#/R-HSA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9794572 https://reactome.org/PathwayBrowser/#/R-HSA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9820842 https://reactome.org/PathwayBrowser/#/R-HSA-9820842 AGO2:endosiRNA hydrolyzes maternal mRNA in the zygote IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9822311 https://reactome.org/PathwayBrowser/#/R-HSA-9822311 CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9822335 https://reactome.org/PathwayBrowser/#/R-HSA-9822335 CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9822437 https://reactome.org/PathwayBrowser/#/R-HSA-9822437 DIS3L2 hydrolyzes uridylated mRNA IEA Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-9825772 https://reactome.org/PathwayBrowser/#/R-HSA-9825772 SIRT1 deacetylates HINT1 dimer TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9830848 https://reactome.org/PathwayBrowser/#/R-HSA-9830848 L protein acts as a cap N7 methyltransferase to modify RSV mRNAs TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-983144 https://reactome.org/PathwayBrowser/#/R-HSA-983144 Transport of Antigen peptide in to ER TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9831948 https://reactome.org/PathwayBrowser/#/R-HSA-9831948 P:PP1 dephosphorylates M2-1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-983422 https://reactome.org/PathwayBrowser/#/R-HSA-983422 Disassembly of COPII coated vesicle TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9836585 https://reactome.org/PathwayBrowser/#/R-HSA-9836585 SUPV3L1:PNPT1 hydrolyzes mitochondrial RNA to yield 4-5 nucleotide oligoribonucleotides TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9836822 https://reactome.org/PathwayBrowser/#/R-HSA-9836822 REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9837419 https://reactome.org/PathwayBrowser/#/R-HSA-9837419 PANK4 hydrolyzes PPANT to pantetheine TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9838004 https://reactome.org/PathwayBrowser/#/R-HSA-9838004 LONP1 degrades mitochondrial inner membrane proteins TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9838081 https://reactome.org/PathwayBrowser/#/R-HSA-9838081 LONP1 degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9838289 https://reactome.org/PathwayBrowser/#/R-HSA-9838289 CLPXP degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9839059 https://reactome.org/PathwayBrowser/#/R-HSA-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) TAS Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-9839072 https://reactome.org/PathwayBrowser/#/R-HSA-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9839105 https://reactome.org/PathwayBrowser/#/R-HSA-9839105 AFG3L2 degrades mitochondrial matrix proteins TAS Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-9839110 https://reactome.org/PathwayBrowser/#/R-HSA-9839110 HTRA2 degrades NDUFA13 (GRIM-19) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9839113 https://reactome.org/PathwayBrowser/#/R-HSA-9839113 AFG3L2 degrades mitochondrial inner membrane proteins TAS Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-9839146 https://reactome.org/PathwayBrowser/#/R-HSA-9839146 YME1L1 degrades mitochondrial inner membrane proteins IEA Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-9839751 https://reactome.org/PathwayBrowser/#/R-HSA-9839751 YME1L1 degrades mitochondrial intermembrane space proteins IEA Homo sapiens 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-HSA-9840408 https://reactome.org/PathwayBrowser/#/R-HSA-9840408 OMA1 cleaves DELE1 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9840795 https://reactome.org/PathwayBrowser/#/R-HSA-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9840833 https://reactome.org/PathwayBrowser/#/R-HSA-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9840884 https://reactome.org/PathwayBrowser/#/R-HSA-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9840949 https://reactome.org/PathwayBrowser/#/R-HSA-9840949 ARSA removes sulfate from SM3 TAS Homo sapiens 15377 R-ALL-1605715 H2O [lysosomal lumen] R-HSA-9841189 https://reactome.org/PathwayBrowser/#/R-HSA-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9841847 https://reactome.org/PathwayBrowser/#/R-HSA-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9853385 https://reactome.org/PathwayBrowser/#/R-HSA-9853385 PPP1CC dephosphorylates PLK1 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9856794 https://reactome.org/PathwayBrowser/#/R-HSA-9856794 Unknown dehydrogenase oxidizes 4-HBz TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9861595 https://reactome.org/PathwayBrowser/#/R-HSA-9861595 Cytosolic H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9861626 https://reactome.org/PathwayBrowser/#/R-HSA-9861626 SIRT4 cleaves lipoyl from DLAT TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9861725 https://reactome.org/PathwayBrowser/#/R-HSA-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9861745 https://reactome.org/PathwayBrowser/#/R-HSA-9861745 Mitochondrial H2O2 decarboxylates PYR to acetate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9865167 https://reactome.org/PathwayBrowser/#/R-HSA-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9865226 https://reactome.org/PathwayBrowser/#/R-HSA-9865226 PP2A dephosphorylates serine-127 of YAP1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9865238 https://reactome.org/PathwayBrowser/#/R-HSA-9865238 PP2A dephosphorylates serine-715 of PDE4D5 in p-S715-PDE4D5:integrin alpha5:integrin beta1:fibronectin IEA Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9865748 https://reactome.org/PathwayBrowser/#/R-HSA-9865748 PDE4D5 in p-S26-ANXA2:PP2A:PDE4D5:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP IEA Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9912527 https://reactome.org/PathwayBrowser/#/R-HSA-9912527 H139Hfs13* PPM1K does not dephosphorylate BCKDH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9912636 https://reactome.org/PathwayBrowser/#/R-HSA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9912655 https://reactome.org/PathwayBrowser/#/R-HSA-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9912747 https://reactome.org/PathwayBrowser/#/R-HSA-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9912751 https://reactome.org/PathwayBrowser/#/R-HSA-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9914271 https://reactome.org/PathwayBrowser/#/R-HSA-9914271 AUH mutants don't synthesize 3-hydroxy-methylglutaryl-CoA TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9915968 https://reactome.org/PathwayBrowser/#/R-HSA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9915971 https://reactome.org/PathwayBrowser/#/R-HSA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9915986 https://reactome.org/PathwayBrowser/#/R-HSA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-HSA-9915993 https://reactome.org/PathwayBrowser/#/R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9915994 https://reactome.org/PathwayBrowser/#/R-HSA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9915997 https://reactome.org/PathwayBrowser/#/R-HSA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-9916401 https://reactome.org/PathwayBrowser/#/R-HSA-9916401 ALOX12 oxidises LTA4 to LXB4 TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9916717 https://reactome.org/PathwayBrowser/#/R-HSA-9916717 ECHS1 mutants don't synthesize beta-hydroxyisobutyryl-CoA TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9916727 https://reactome.org/PathwayBrowser/#/R-HSA-9916727 HIBCH mutants don't synthesize beta-hydroxyisobutyrate TAS Homo sapiens 15377 R-ALL-113521 H2O [mitochondrial matrix] R-HSA-9929439 https://reactome.org/PathwayBrowser/#/R-HSA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-997309 https://reactome.org/PathwayBrowser/#/R-HSA-997309 Dephosphorylation of STAT1 by SHP2 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-997311 https://reactome.org/PathwayBrowser/#/R-HSA-997311 Dephosphorylation of TYK2 by PTP1B TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-HSA-997314 https://reactome.org/PathwayBrowser/#/R-HSA-997314 Dephosphorylation of JAK1 by SHP1 TAS Homo sapiens 15377 R-ALL-113518 H2O [nucleoplasm] R-HSA-997326 https://reactome.org/PathwayBrowser/#/R-HSA-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP TAS Homo sapiens 15377 R-ALL-109276 H2O [extracellular region] R-MMU-109278 https://reactome.org/PathwayBrowser/#/R-MMU-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-109291 https://reactome.org/PathwayBrowser/#/R-MMU-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109380 https://reactome.org/PathwayBrowser/#/R-MMU-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109387 https://reactome.org/PathwayBrowser/#/R-MMU-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109415 https://reactome.org/PathwayBrowser/#/R-MMU-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109449 https://reactome.org/PathwayBrowser/#/R-MMU-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109470 https://reactome.org/PathwayBrowser/#/R-MMU-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-109480 https://reactome.org/PathwayBrowser/#/R-MMU-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-109514 https://reactome.org/PathwayBrowser/#/R-MMU-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111742 https://reactome.org/PathwayBrowser/#/R-MMU-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111751 https://reactome.org/PathwayBrowser/#/R-MMU-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111804 https://reactome.org/PathwayBrowser/#/R-MMU-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111879 https://reactome.org/PathwayBrowser/#/R-MMU-111879 PIP2 hydrolysis IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111955 https://reactome.org/PathwayBrowser/#/R-MMU-111955 cAMP hydrolysis by Cam-PDE 1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-111962 https://reactome.org/PathwayBrowser/#/R-MMU-111962 PDE4A,C,D hydrolyse cAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-112037 https://reactome.org/PathwayBrowser/#/R-MMU-112037 Inactivation of PLC beta IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-113503 https://reactome.org/PathwayBrowser/#/R-MMU-113503 PP2A mediated localization of RB1 protein in chromatin IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1169192 https://reactome.org/PathwayBrowser/#/R-MMU-1169192 PTP1B dephosphorylates GHR IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1183128 https://reactome.org/PathwayBrowser/#/R-MMU-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1237129 https://reactome.org/PathwayBrowser/#/R-MMU-1237129 Acireductone is created IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1247910 https://reactome.org/PathwayBrowser/#/R-MMU-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1247935 https://reactome.org/PathwayBrowser/#/R-MMU-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-1363274 https://reactome.org/PathwayBrowser/#/R-MMU-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-1363276 https://reactome.org/PathwayBrowser/#/R-MMU-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1369028 https://reactome.org/PathwayBrowser/#/R-MMU-1369028 ABCAs mediate lipid efflux IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1369052 https://reactome.org/PathwayBrowser/#/R-MMU-1369052 ABCAs mediate lipid influx IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1369065 https://reactome.org/PathwayBrowser/#/R-MMU-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-139906 https://reactome.org/PathwayBrowser/#/R-MMU-139906 Activation of BAD by calcineurin IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-140359 https://reactome.org/PathwayBrowser/#/R-MMU-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1454916 https://reactome.org/PathwayBrowser/#/R-MMU-1454916 The ABCC family mediates organic anion transport IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1454928 https://reactome.org/PathwayBrowser/#/R-MMU-1454928 ABCG4 may mediate cholesterol efflux IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1467457 https://reactome.org/PathwayBrowser/#/R-MMU-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1467466 https://reactome.org/PathwayBrowser/#/R-MMU-1467466 ABCA4 mediates atRAL transport IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1474146 https://reactome.org/PathwayBrowser/#/R-MMU-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482543 https://reactome.org/PathwayBrowser/#/R-MMU-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482545 https://reactome.org/PathwayBrowser/#/R-MMU-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482571 https://reactome.org/PathwayBrowser/#/R-MMU-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482604 https://reactome.org/PathwayBrowser/#/R-MMU-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482612 https://reactome.org/PathwayBrowser/#/R-MMU-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482629 https://reactome.org/PathwayBrowser/#/R-MMU-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482656 https://reactome.org/PathwayBrowser/#/R-MMU-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482679 https://reactome.org/PathwayBrowser/#/R-MMU-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482685 https://reactome.org/PathwayBrowser/#/R-MMU-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482696 https://reactome.org/PathwayBrowser/#/R-MMU-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1482745 https://reactome.org/PathwayBrowser/#/R-MMU-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1482759 https://reactome.org/PathwayBrowser/#/R-MMU-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482771 https://reactome.org/PathwayBrowser/#/R-MMU-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482776 https://reactome.org/PathwayBrowser/#/R-MMU-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482777 https://reactome.org/PathwayBrowser/#/R-MMU-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482811 https://reactome.org/PathwayBrowser/#/R-MMU-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482816 https://reactome.org/PathwayBrowser/#/R-MMU-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482825 https://reactome.org/PathwayBrowser/#/R-MMU-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482827 https://reactome.org/PathwayBrowser/#/R-MMU-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482828 https://reactome.org/PathwayBrowser/#/R-MMU-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1482847 https://reactome.org/PathwayBrowser/#/R-MMU-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482856 https://reactome.org/PathwayBrowser/#/R-MMU-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482862 https://reactome.org/PathwayBrowser/#/R-MMU-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482868 https://reactome.org/PathwayBrowser/#/R-MMU-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482884 https://reactome.org/PathwayBrowser/#/R-MMU-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482887 https://reactome.org/PathwayBrowser/#/R-MMU-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482892 https://reactome.org/PathwayBrowser/#/R-MMU-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482897 https://reactome.org/PathwayBrowser/#/R-MMU-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482900 https://reactome.org/PathwayBrowser/#/R-MMU-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482907 https://reactome.org/PathwayBrowser/#/R-MMU-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482920 https://reactome.org/PathwayBrowser/#/R-MMU-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1482932 https://reactome.org/PathwayBrowser/#/R-MMU-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483096 https://reactome.org/PathwayBrowser/#/R-MMU-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483112 https://reactome.org/PathwayBrowser/#/R-MMU-1483112 GPCho is hydrolyzed to Cho and G3P by Gpcpd1 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483159 https://reactome.org/PathwayBrowser/#/R-MMU-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483182 https://reactome.org/PathwayBrowser/#/R-MMU-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483203 https://reactome.org/PathwayBrowser/#/R-MMU-1483203 PA is dephosphorylated to DAG by LPIN IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1483231 https://reactome.org/PathwayBrowser/#/R-MMU-1483231 GPETA is hydrolyzed to ETA and G3P by Gpcpd1 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-159425 https://reactome.org/PathwayBrowser/#/R-MMU-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602368 https://reactome.org/PathwayBrowser/#/R-MMU-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602374 https://reactome.org/PathwayBrowser/#/R-MMU-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602377 https://reactome.org/PathwayBrowser/#/R-MMU-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602398 https://reactome.org/PathwayBrowser/#/R-MMU-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602399 https://reactome.org/PathwayBrowser/#/R-MMU-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602417 https://reactome.org/PathwayBrowser/#/R-MMU-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-1602446 https://reactome.org/PathwayBrowser/#/R-MMU-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605591 https://reactome.org/PathwayBrowser/#/R-MMU-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605595 https://reactome.org/PathwayBrowser/#/R-MMU-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605624 https://reactome.org/PathwayBrowser/#/R-MMU-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605632 https://reactome.org/PathwayBrowser/#/R-MMU-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1605723 https://reactome.org/PathwayBrowser/#/R-MMU-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605724 https://reactome.org/PathwayBrowser/#/R-MMU-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605736 https://reactome.org/PathwayBrowser/#/R-MMU-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1605768 https://reactome.org/PathwayBrowser/#/R-MMU-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1606312 https://reactome.org/PathwayBrowser/#/R-MMU-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1606564 https://reactome.org/PathwayBrowser/#/R-MMU-1606564 GALC hydrolyzes GalCer IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1606583 https://reactome.org/PathwayBrowser/#/R-MMU-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1606602 https://reactome.org/PathwayBrowser/#/R-MMU-1606602 ASAH1 hydrolyzes ceramide IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1606789 https://reactome.org/PathwayBrowser/#/R-MMU-1606789 ARSB hydrolyses DS IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-1606839 https://reactome.org/PathwayBrowser/#/R-MMU-1606839 ARSC hydrolyzes steroid sulfates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1614524 https://reactome.org/PathwayBrowser/#/R-MMU-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1614583 https://reactome.org/PathwayBrowser/#/R-MMU-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to pyruvate and H2S IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-162425 https://reactome.org/PathwayBrowser/#/R-MMU-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-162729 https://reactome.org/PathwayBrowser/#/R-MMU-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-162857 https://reactome.org/PathwayBrowser/#/R-MMU-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1630304 https://reactome.org/PathwayBrowser/#/R-MMU-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1630306 https://reactome.org/PathwayBrowser/#/R-MMU-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1638032 https://reactome.org/PathwayBrowser/#/R-MMU-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1638053 https://reactome.org/PathwayBrowser/#/R-MMU-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1638821 https://reactome.org/PathwayBrowser/#/R-MMU-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-164832 https://reactome.org/PathwayBrowser/#/R-MMU-164832 ATPase synthesizes ATP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1667005 https://reactome.org/PathwayBrowser/#/R-MMU-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675795 https://reactome.org/PathwayBrowser/#/R-MMU-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675824 https://reactome.org/PathwayBrowser/#/R-MMU-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675836 https://reactome.org/PathwayBrowser/#/R-MMU-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675949 https://reactome.org/PathwayBrowser/#/R-MMU-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675988 https://reactome.org/PathwayBrowser/#/R-MMU-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1675994 https://reactome.org/PathwayBrowser/#/R-MMU-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676005 https://reactome.org/PathwayBrowser/#/R-MMU-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676020 https://reactome.org/PathwayBrowser/#/R-MMU-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676065 https://reactome.org/PathwayBrowser/#/R-MMU-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676105 https://reactome.org/PathwayBrowser/#/R-MMU-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676114 https://reactome.org/PathwayBrowser/#/R-MMU-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676124 https://reactome.org/PathwayBrowser/#/R-MMU-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676141 https://reactome.org/PathwayBrowser/#/R-MMU-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676149 https://reactome.org/PathwayBrowser/#/R-MMU-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676162 https://reactome.org/PathwayBrowser/#/R-MMU-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676164 https://reactome.org/PathwayBrowser/#/R-MMU-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676174 https://reactome.org/PathwayBrowser/#/R-MMU-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676177 https://reactome.org/PathwayBrowser/#/R-MMU-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676203 https://reactome.org/PathwayBrowser/#/R-MMU-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1676204 https://reactome.org/PathwayBrowser/#/R-MMU-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1678650 https://reactome.org/PathwayBrowser/#/R-MMU-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1678708 https://reactome.org/PathwayBrowser/#/R-MMU-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1678716 https://reactome.org/PathwayBrowser/#/R-MMU-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1678742 https://reactome.org/PathwayBrowser/#/R-MMU-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1678854 https://reactome.org/PathwayBrowser/#/R-MMU-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-170153 https://reactome.org/PathwayBrowser/#/R-MMU-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-170158 https://reactome.org/PathwayBrowser/#/R-MMU-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-170161 https://reactome.org/PathwayBrowser/#/R-MMU-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-173739 https://reactome.org/PathwayBrowser/#/R-MMU-173739 Spontaneous hydrolysis of C3 thioester IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-174110 https://reactome.org/PathwayBrowser/#/R-MMU-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-174124 https://reactome.org/PathwayBrowser/#/R-MMU-174124 Dephosphorylation of phospho-Cdh1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-174391 https://reactome.org/PathwayBrowser/#/R-MMU-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-174401 https://reactome.org/PathwayBrowser/#/R-MMU-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-174439 https://reactome.org/PathwayBrowser/#/R-MMU-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-176606 https://reactome.org/PathwayBrowser/#/R-MMU-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-177923 https://reactome.org/PathwayBrowser/#/R-MMU-177923 Sustained activation of SRC kinase by SHP2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-177924 https://reactome.org/PathwayBrowser/#/R-MMU-177924 Dephosphorylation of Gab1 by SHP2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-177926 https://reactome.org/PathwayBrowser/#/R-MMU-177926 Dephosphorylation of PAG by SHP2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-177935 https://reactome.org/PathwayBrowser/#/R-MMU-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1793182 https://reactome.org/PathwayBrowser/#/R-MMU-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1793186 https://reactome.org/PathwayBrowser/#/R-MMU-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1793207 https://reactome.org/PathwayBrowser/#/R-MMU-1793207 ARSB hydrolyses C4S/C6S chains IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-1793209 https://reactome.org/PathwayBrowser/#/R-MMU-1793209 HYAL1 hydrolyses Chondroitin chains IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855154 https://reactome.org/PathwayBrowser/#/R-MMU-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855159 https://reactome.org/PathwayBrowser/#/R-MMU-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-1855163 https://reactome.org/PathwayBrowser/#/R-MMU-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855165 https://reactome.org/PathwayBrowser/#/R-MMU-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855166 https://reactome.org/PathwayBrowser/#/R-MMU-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855171 https://reactome.org/PathwayBrowser/#/R-MMU-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855174 https://reactome.org/PathwayBrowser/#/R-MMU-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855177 https://reactome.org/PathwayBrowser/#/R-MMU-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855180 https://reactome.org/PathwayBrowser/#/R-MMU-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855198 https://reactome.org/PathwayBrowser/#/R-MMU-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-1855200 https://reactome.org/PathwayBrowser/#/R-MMU-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855202 https://reactome.org/PathwayBrowser/#/R-MMU-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855205 https://reactome.org/PathwayBrowser/#/R-MMU-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855208 https://reactome.org/PathwayBrowser/#/R-MMU-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855210 https://reactome.org/PathwayBrowser/#/R-MMU-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855211 https://reactome.org/PathwayBrowser/#/R-MMU-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855213 https://reactome.org/PathwayBrowser/#/R-MMU-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855214 https://reactome.org/PathwayBrowser/#/R-MMU-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855218 https://reactome.org/PathwayBrowser/#/R-MMU-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855219 https://reactome.org/PathwayBrowser/#/R-MMU-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855221 https://reactome.org/PathwayBrowser/#/R-MMU-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855222 https://reactome.org/PathwayBrowser/#/R-MMU-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-1855225 https://reactome.org/PathwayBrowser/#/R-MMU-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1855232 https://reactome.org/PathwayBrowser/#/R-MMU-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-1861788 https://reactome.org/PathwayBrowser/#/R-MMU-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-188979 https://reactome.org/PathwayBrowser/#/R-MMU-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-189053 https://reactome.org/PathwayBrowser/#/R-MMU-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-189062 https://reactome.org/PathwayBrowser/#/R-MMU-189062 lactose + H2O => D-glucose + D-galactose IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-189069 https://reactome.org/PathwayBrowser/#/R-MMU-189069 sucrose + H2O => glucose + fructose IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-189102 https://reactome.org/PathwayBrowser/#/R-MMU-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-189406 https://reactome.org/PathwayBrowser/#/R-MMU-189406 4 PBGs bind to form HMB IEA Mus musculus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-189488 https://reactome.org/PathwayBrowser/#/R-MMU-189488 UROS transforms HMB to URO3 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-191101 https://reactome.org/PathwayBrowser/#/R-MMU-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-191108 https://reactome.org/PathwayBrowser/#/R-MMU-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-191114 https://reactome.org/PathwayBrowser/#/R-MMU-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-191116 https://reactome.org/PathwayBrowser/#/R-MMU-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-192331 https://reactome.org/PathwayBrowser/#/R-MMU-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192417 https://reactome.org/PathwayBrowser/#/R-MMU-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192422 https://reactome.org/PathwayBrowser/#/R-MMU-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192425 https://reactome.org/PathwayBrowser/#/R-MMU-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192430 https://reactome.org/PathwayBrowser/#/R-MMU-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192434 https://reactome.org/PathwayBrowser/#/R-MMU-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-192475 https://reactome.org/PathwayBrowser/#/R-MMU-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193362 https://reactome.org/PathwayBrowser/#/R-MMU-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-193385 https://reactome.org/PathwayBrowser/#/R-MMU-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-193535 https://reactome.org/PathwayBrowser/#/R-MMU-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193711 https://reactome.org/PathwayBrowser/#/R-MMU-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193727 https://reactome.org/PathwayBrowser/#/R-MMU-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193743 https://reactome.org/PathwayBrowser/#/R-MMU-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193766 https://reactome.org/PathwayBrowser/#/R-MMU-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-196950 https://reactome.org/PathwayBrowser/#/R-MMU-196950 2xTRAP hydrolyzes FMN to RIB IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-197186 https://reactome.org/PathwayBrowser/#/R-MMU-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-199425 https://reactome.org/PathwayBrowser/#/R-MMU-199425 PHLPP dephosphorylates S473 in AKT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-199456 https://reactome.org/PathwayBrowser/#/R-MMU-199456 PTEN dephosphorylates PIP3 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-199959 https://reactome.org/PathwayBrowser/#/R-MMU-199959 ERKs are inactivated by protein phosphatase 2A IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-200661 https://reactome.org/PathwayBrowser/#/R-MMU-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-200740 https://reactome.org/PathwayBrowser/#/R-MMU-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-201035 https://reactome.org/PathwayBrowser/#/R-MMU-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-201790 https://reactome.org/PathwayBrowser/#/R-MMU-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-202214 https://reactome.org/PathwayBrowser/#/R-MMU-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022368 https://reactome.org/PathwayBrowser/#/R-MMU-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-202237 https://reactome.org/PathwayBrowser/#/R-MMU-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022378 https://reactome.org/PathwayBrowser/#/R-MMU-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022379 https://reactome.org/PathwayBrowser/#/R-MMU-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022381 https://reactome.org/PathwayBrowser/#/R-MMU-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022383 https://reactome.org/PathwayBrowser/#/R-MMU-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022396 https://reactome.org/PathwayBrowser/#/R-MMU-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022398 https://reactome.org/PathwayBrowser/#/R-MMU-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022399 https://reactome.org/PathwayBrowser/#/R-MMU-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022403 https://reactome.org/PathwayBrowser/#/R-MMU-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022405 https://reactome.org/PathwayBrowser/#/R-MMU-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022411 https://reactome.org/PathwayBrowser/#/R-MMU-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2022412 https://reactome.org/PathwayBrowser/#/R-MMU-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-ALL-2022884 H2O [Golgi lumen] R-MMU-2022887 https://reactome.org/PathwayBrowser/#/R-MMU-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2023971 https://reactome.org/PathwayBrowser/#/R-MMU-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2023973 https://reactome.org/PathwayBrowser/#/R-MMU-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-202407 https://reactome.org/PathwayBrowser/#/R-MMU-202407 PLC-gamma1 hydrolyses PIP2 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2028294 https://reactome.org/PathwayBrowser/#/R-MMU-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2029468 https://reactome.org/PathwayBrowser/#/R-MMU-2029468 Conversion of PA into DAG by PAP-1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2029471 https://reactome.org/PathwayBrowser/#/R-MMU-2029471 Hydrolysis of PC to PA by PLD IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2029475 https://reactome.org/PathwayBrowser/#/R-MMU-2029475 Production of AA by iPLA2 upon FCGR activation IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 Depalmitoylation of eNOS IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-203797 https://reactome.org/PathwayBrowser/#/R-MMU-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-204169 https://reactome.org/PathwayBrowser/#/R-MMU-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046083 https://reactome.org/PathwayBrowser/#/R-MMU-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046088 https://reactome.org/PathwayBrowser/#/R-MMU-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046090 https://reactome.org/PathwayBrowser/#/R-MMU-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046094 https://reactome.org/PathwayBrowser/#/R-MMU-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046095 https://reactome.org/PathwayBrowser/#/R-MMU-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2046100 https://reactome.org/PathwayBrowser/#/R-MMU-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2065355 https://reactome.org/PathwayBrowser/#/R-MMU-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2065357 https://reactome.org/PathwayBrowser/#/R-MMU-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-2066778 https://reactome.org/PathwayBrowser/#/R-MMU-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-2066779 https://reactome.org/PathwayBrowser/#/R-MMU-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2090037 https://reactome.org/PathwayBrowser/#/R-MMU-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2090038 https://reactome.org/PathwayBrowser/#/R-MMU-2090038 NAGLU hydrolyses heparan chain(2) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2090043 https://reactome.org/PathwayBrowser/#/R-MMU-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2090079 https://reactome.org/PathwayBrowser/#/R-MMU-2090079 GLB1 hydrolyses linker chain(2) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-209055 https://reactome.org/PathwayBrowser/#/R-MMU-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15377 R-ALL-351603 H2O [secretory granule lumen] R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2105001 https://reactome.org/PathwayBrowser/#/R-MMU-2105001 HEXA cleaves the terminal GalNAc from DS IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2130725 https://reactome.org/PathwayBrowser/#/R-MMU-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2160874 https://reactome.org/PathwayBrowser/#/R-MMU-2160874 HYAL1 hydrolyses (HA)50 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161195 https://reactome.org/PathwayBrowser/#/R-MMU-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161526 https://reactome.org/PathwayBrowser/#/R-MMU-2161526 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161533 https://reactome.org/PathwayBrowser/#/R-MMU-2161533 abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate TAS Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2161646 https://reactome.org/PathwayBrowser/#/R-MMU-2161646 PGA2 is dehydrated to 15d-PGA2 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161791 https://reactome.org/PathwayBrowser/#/R-MMU-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161959 https://reactome.org/PathwayBrowser/#/R-MMU-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161961 https://reactome.org/PathwayBrowser/#/R-MMU-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2161999 https://reactome.org/PathwayBrowser/#/R-MMU-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-2162187 https://reactome.org/PathwayBrowser/#/R-MMU-2162187 COQ6 hydroxylates DHB IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2162225 https://reactome.org/PathwayBrowser/#/R-MMU-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2162226 https://reactome.org/PathwayBrowser/#/R-MMU-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-2162227 https://reactome.org/PathwayBrowser/#/R-MMU-2162227 GUSB tetramer hydrolyses (HA)2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-216723 https://reactome.org/PathwayBrowser/#/R-MMU-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-216757 https://reactome.org/PathwayBrowser/#/R-MMU-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2187401 https://reactome.org/PathwayBrowser/#/R-MMU-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-2309773 https://reactome.org/PathwayBrowser/#/R-MMU-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2393939 https://reactome.org/PathwayBrowser/#/R-MMU-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-2393954 https://reactome.org/PathwayBrowser/#/R-MMU-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2408528 https://reactome.org/PathwayBrowser/#/R-MMU-2408528 Excess SeMet is cleaved into MeSeH by PXLP-K211-Cth TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2408551 https://reactome.org/PathwayBrowser/#/R-MMU-2408551 SeMet is converted to AdoSeMet by MAT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2454118 https://reactome.org/PathwayBrowser/#/R-MMU-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2465924 https://reactome.org/PathwayBrowser/#/R-MMU-2465924 OPN1LW binds 11cRAL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2466085 https://reactome.org/PathwayBrowser/#/R-MMU-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2529015 https://reactome.org/PathwayBrowser/#/R-MMU-2529015 Dephosphorylation of CK2-modified condensin I IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2584246 https://reactome.org/PathwayBrowser/#/R-MMU-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2632521 https://reactome.org/PathwayBrowser/#/R-MMU-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-265783 https://reactome.org/PathwayBrowser/#/R-MMU-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-266012 https://reactome.org/PathwayBrowser/#/R-MMU-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-266046 https://reactome.org/PathwayBrowser/#/R-MMU-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-266051 https://reactome.org/PathwayBrowser/#/R-MMU-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-266070 https://reactome.org/PathwayBrowser/#/R-MMU-266070 LTC4 is exported from the cytosol by ABCC1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-266072 https://reactome.org/PathwayBrowser/#/R-MMU-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-266082 https://reactome.org/PathwayBrowser/#/R-MMU-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2730847 https://reactome.org/PathwayBrowser/#/R-MMU-2730847 Hydrolysis of PIP2 by PLCG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2730849 https://reactome.org/PathwayBrowser/#/R-MMU-2730849 Calcineurin binds and dephosphorylates NFAT IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-2855047 https://reactome.org/PathwayBrowser/#/R-MMU-2855047 Hydrolysis of internal thioester in C4b IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-2995330 https://reactome.org/PathwayBrowser/#/R-MMU-2995330 COX10 transforms heme to heme O IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-2995334 https://reactome.org/PathwayBrowser/#/R-MMU-2995334 COX15 transforms heme O to heme A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-2995388 https://reactome.org/PathwayBrowser/#/R-MMU-2995388 PP2A dephosphorylates BANF1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3002811 https://reactome.org/PathwayBrowser/#/R-MMU-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3095901 https://reactome.org/PathwayBrowser/#/R-MMU-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3215295 https://reactome.org/PathwayBrowser/#/R-MMU-3215295 USP7 deubiquitinates MDM2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3215310 https://reactome.org/PathwayBrowser/#/R-MMU-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3247569 https://reactome.org/PathwayBrowser/#/R-MMU-3247569 PADI4 deiminates Histones IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-3262512 https://reactome.org/PathwayBrowser/#/R-MMU-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-3266566 https://reactome.org/PathwayBrowser/#/R-MMU-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-3322995 https://reactome.org/PathwayBrowser/#/R-MMU-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-3323013 https://reactome.org/PathwayBrowser/#/R-MMU-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3341277 https://reactome.org/PathwayBrowser/#/R-MMU-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-3341296 https://reactome.org/PathwayBrowser/#/R-MMU-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3341343 https://reactome.org/PathwayBrowser/#/R-MMU-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-3341397 https://reactome.org/PathwayBrowser/#/R-MMU-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3343700 https://reactome.org/PathwayBrowser/#/R-MMU-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3371467 https://reactome.org/PathwayBrowser/#/R-MMU-3371467 SIRT1 deacetylates HSF1 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-3446785 https://reactome.org/PathwayBrowser/#/R-MMU-3446785 Ptpmt1 dephosphorylates PGP to PG TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-350604 https://reactome.org/PathwayBrowser/#/R-MMU-350604 Agmatine + H2O <=> putrescine + urea IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3640872 https://reactome.org/PathwayBrowser/#/R-MMU-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3697882 https://reactome.org/PathwayBrowser/#/R-MMU-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-3697894 https://reactome.org/PathwayBrowser/#/R-MMU-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3697899 https://reactome.org/PathwayBrowser/#/R-MMU-3697899 Atp7a transfers Cu from Atox1 to Sod3 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3769447 https://reactome.org/PathwayBrowser/#/R-MMU-3769447 HDAC1:2-containing complex deacetylate histones IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-377643 https://reactome.org/PathwayBrowser/#/R-MMU-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3777129 https://reactome.org/PathwayBrowser/#/R-MMU-3777129 HDAC3 containing complexes deacetylate histone IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-3781018 https://reactome.org/PathwayBrowser/#/R-MMU-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3782637 https://reactome.org/PathwayBrowser/#/R-MMU-3782637 HDAC8 deacetylates histones IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-3782655 https://reactome.org/PathwayBrowser/#/R-MMU-3782655 HDAC10 deacetylates histone IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-380949 https://reactome.org/PathwayBrowser/#/R-MMU-380949 AMPK is dephosphorylated IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-382553 https://reactome.org/PathwayBrowser/#/R-MMU-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-382560 https://reactome.org/PathwayBrowser/#/R-MMU-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-382575 https://reactome.org/PathwayBrowser/#/R-MMU-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-383190 https://reactome.org/PathwayBrowser/#/R-MMU-383190 HCO3- transport through ion channel IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-389986 https://reactome.org/PathwayBrowser/#/R-MMU-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-390252 https://reactome.org/PathwayBrowser/#/R-MMU-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-390329 https://reactome.org/PathwayBrowser/#/R-MMU-390329 Dephosphorylation of AKT by PP2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-390393 https://reactome.org/PathwayBrowser/#/R-MMU-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-399998 https://reactome.org/PathwayBrowser/#/R-MMU-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4084976 https://reactome.org/PathwayBrowser/#/R-MMU-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4084989 https://reactome.org/PathwayBrowser/#/R-MMU-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4084994 https://reactome.org/PathwayBrowser/#/R-MMU-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-4084999 https://reactome.org/PathwayBrowser/#/R-MMU-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4085021 https://reactome.org/PathwayBrowser/#/R-MMU-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4085029 https://reactome.org/PathwayBrowser/#/R-MMU-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4086392 https://reactome.org/PathwayBrowser/#/R-MMU-4086392 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-4088141 https://reactome.org/PathwayBrowser/#/R-MMU-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4093339 https://reactome.org/PathwayBrowser/#/R-MMU-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-416559 https://reactome.org/PathwayBrowser/#/R-MMU-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-418553 https://reactome.org/PathwayBrowser/#/R-MMU-418553 cAMP degradation by Phosphodiesterases IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428205 https://reactome.org/PathwayBrowser/#/R-MMU-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428231 https://reactome.org/PathwayBrowser/#/R-MMU-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428262 https://reactome.org/PathwayBrowser/#/R-MMU-428262 ACER3 hydrolyzes phytoceramide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428664 https://reactome.org/PathwayBrowser/#/R-MMU-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-428690 https://reactome.org/PathwayBrowser/#/R-MMU-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-428696 https://reactome.org/PathwayBrowser/#/R-MMU-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-429860 https://reactome.org/PathwayBrowser/#/R-MMU-429860 DCP1-DCP2 complex decaps mRNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-429955 https://reactome.org/PathwayBrowser/#/R-MMU-429955 CCR4-NOT complex deadenylates mRNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-429961 https://reactome.org/PathwayBrowser/#/R-MMU-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-429992 https://reactome.org/PathwayBrowser/#/R-MMU-429992 PARN deadenylates mRNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-430021 https://reactome.org/PathwayBrowser/#/R-MMU-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-430028 https://reactome.org/PathwayBrowser/#/R-MMU-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-432010 https://reactome.org/PathwayBrowser/#/R-MMU-432010 Aquaporin-1 passively transports water into cell IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-432010 https://reactome.org/PathwayBrowser/#/R-MMU-432010 Aquaporin-1 passively transports water into cell IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-432054 https://reactome.org/PathwayBrowser/#/R-MMU-432054 Aquaporin-1 passively transports water out of cell IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-432054 https://reactome.org/PathwayBrowser/#/R-MMU-432054 Aquaporin-1 passively transports water out of cell IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-432065 https://reactome.org/PathwayBrowser/#/R-MMU-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-432065 https://reactome.org/PathwayBrowser/#/R-MMU-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-432067 https://reactome.org/PathwayBrowser/#/R-MMU-432067 Aquaporin-4 passively transports water out of cell IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-432067 https://reactome.org/PathwayBrowser/#/R-MMU-432067 Aquaporin-4 passively transports water out of cell IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-4419948 https://reactome.org/PathwayBrowser/#/R-MMU-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-445714 https://reactome.org/PathwayBrowser/#/R-MMU-445714 Aquaporin-3 passively transports water out of cell IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-445714 https://reactome.org/PathwayBrowser/#/R-MMU-445714 Aquaporin-3 passively transports water out of cell IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-449937 https://reactome.org/PathwayBrowser/#/R-MMU-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-452036 https://reactome.org/PathwayBrowser/#/R-MMU-452036 arginine + H2O => ornithine + urea [ARG2] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4551451 https://reactome.org/PathwayBrowser/#/R-MMU-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-4641236 https://reactome.org/PathwayBrowser/#/R-MMU-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-507868 https://reactome.org/PathwayBrowser/#/R-MMU-507868 Aquaporins passively transport water into cells IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-507868 https://reactome.org/PathwayBrowser/#/R-MMU-507868 Aquaporins passively transport water into cells IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-507870 https://reactome.org/PathwayBrowser/#/R-MMU-507870 Aquaporins passively transport water out of cells IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-507870 https://reactome.org/PathwayBrowser/#/R-MMU-507870 Aquaporins passively transport water out of cells IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5221130 https://reactome.org/PathwayBrowser/#/R-MMU-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5223313 https://reactome.org/PathwayBrowser/#/R-MMU-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5223317 https://reactome.org/PathwayBrowser/#/R-MMU-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5251955 https://reactome.org/PathwayBrowser/#/R-MMU-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5251959 https://reactome.org/PathwayBrowser/#/R-MMU-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5251989 https://reactome.org/PathwayBrowser/#/R-MMU-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5362459 https://reactome.org/PathwayBrowser/#/R-MMU-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5433072 https://reactome.org/PathwayBrowser/#/R-MMU-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5433074 https://reactome.org/PathwayBrowser/#/R-MMU-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-548843 https://reactome.org/PathwayBrowser/#/R-MMU-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5603114 https://reactome.org/PathwayBrowser/#/R-MMU-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5607735 https://reactome.org/PathwayBrowser/#/R-MMU-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5618093 https://reactome.org/PathwayBrowser/#/R-MMU-5618093 ATP hydrolysis by HSP90 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5623513 https://reactome.org/PathwayBrowser/#/R-MMU-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5628905 https://reactome.org/PathwayBrowser/#/R-MMU-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5631885 https://reactome.org/PathwayBrowser/#/R-MMU-5631885 PRDX1 overoxidizes IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5649705 https://reactome.org/PathwayBrowser/#/R-MMU-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5651828 https://reactome.org/PathwayBrowser/#/R-MMU-5651828 PARG dePARylates PARP1,PARP2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5653770 https://reactome.org/PathwayBrowser/#/R-MMU-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5653786 https://reactome.org/PathwayBrowser/#/R-MMU-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5659861 https://reactome.org/PathwayBrowser/#/R-MMU-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Mus musculus 15377 R-ALL-5668574 H2O [melanosome lumen] R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5665809 https://reactome.org/PathwayBrowser/#/R-MMU-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5672957 https://reactome.org/PathwayBrowser/#/R-MMU-5672957 PP2A dephosphorylates KSR1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5672961 https://reactome.org/PathwayBrowser/#/R-MMU-5672961 PP2A dephosphorylates inactive RAFs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5675373 https://reactome.org/PathwayBrowser/#/R-MMU-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5675376 https://reactome.org/PathwayBrowser/#/R-MMU-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5675431 https://reactome.org/PathwayBrowser/#/R-MMU-5675431 PP2A dephosphorylates RAF1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5675433 https://reactome.org/PathwayBrowser/#/R-MMU-5675433 PP5 dephosphorylates RAF1 S338 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5676637 https://reactome.org/PathwayBrowser/#/R-MMU-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5678706 https://reactome.org/PathwayBrowser/#/R-MMU-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5678863 https://reactome.org/PathwayBrowser/#/R-MMU-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5679041 https://reactome.org/PathwayBrowser/#/R-MMU-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5682285 https://reactome.org/PathwayBrowser/#/R-MMU-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5683405 https://reactome.org/PathwayBrowser/#/R-MMU-5683405 PPP5C dephosphorylates TP53BP1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5683714 https://reactome.org/PathwayBrowser/#/R-MMU-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5683967 https://reactome.org/PathwayBrowser/#/R-MMU-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Mus musculus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-MMU-5684864 https://reactome.org/PathwayBrowser/#/R-MMU-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Mus musculus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-MMU-5685902 https://reactome.org/PathwayBrowser/#/R-MMU-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5685994 https://reactome.org/PathwayBrowser/#/R-MMU-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5687464 https://reactome.org/PathwayBrowser/#/R-MMU-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5687664 https://reactome.org/PathwayBrowser/#/R-MMU-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5687758 https://reactome.org/PathwayBrowser/#/R-MMU-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5688797 https://reactome.org/PathwayBrowser/#/R-MMU-5688797 ATXN3 family cleave Ub chains IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5688837 https://reactome.org/PathwayBrowser/#/R-MMU-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5689000 https://reactome.org/PathwayBrowser/#/R-MMU-5689000 AADAC deacetylates PHEN IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5689950 https://reactome.org/PathwayBrowser/#/R-MMU-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5689972 https://reactome.org/PathwayBrowser/#/R-MMU-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5689973 https://reactome.org/PathwayBrowser/#/R-MMU-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690043 https://reactome.org/PathwayBrowser/#/R-MMU-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5690066 https://reactome.org/PathwayBrowser/#/R-MMU-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5690080 https://reactome.org/PathwayBrowser/#/R-MMU-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690152 https://reactome.org/PathwayBrowser/#/R-MMU-5690152 USP5 cleaves polyubiquitin IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5690157 https://reactome.org/PathwayBrowser/#/R-MMU-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690159 https://reactome.org/PathwayBrowser/#/R-MMU-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690196 https://reactome.org/PathwayBrowser/#/R-MMU-5690196 USP8 deubiquitinates RNF128 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690319 https://reactome.org/PathwayBrowser/#/R-MMU-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-5690517 https://reactome.org/PathwayBrowser/#/R-MMU-5690517 PPT1 hydrolyses palmitoylated proteins IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5690759 https://reactome.org/PathwayBrowser/#/R-MMU-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5690790 https://reactome.org/PathwayBrowser/#/R-MMU-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690808 https://reactome.org/PathwayBrowser/#/R-MMU-5690808 UCHL3, SENP8 cleave NEDD8 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690856 https://reactome.org/PathwayBrowser/#/R-MMU-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5690870 https://reactome.org/PathwayBrowser/#/R-MMU-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5691381 https://reactome.org/PathwayBrowser/#/R-MMU-5691381 MYSM1 deubiquitinates Histone H2A IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5691411 https://reactome.org/PathwayBrowser/#/R-MMU-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5691439 https://reactome.org/PathwayBrowser/#/R-MMU-5691439 BRISC complex deubiquitinates NLRP3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5691507 https://reactome.org/PathwayBrowser/#/R-MMU-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5691512 https://reactome.org/PathwayBrowser/#/R-MMU-5691512 APEH hydrolyses NAc-Ser-protein IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5692462 https://reactome.org/PathwayBrowser/#/R-MMU-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5692480 https://reactome.org/PathwayBrowser/#/R-MMU-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5692754 https://reactome.org/PathwayBrowser/#/R-MMU-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5693153 https://reactome.org/PathwayBrowser/#/R-MMU-5693153 PPM1K dephosphorylates p-BCKDH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5693373 https://reactome.org/PathwayBrowser/#/R-MMU-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5693608 https://reactome.org/PathwayBrowser/#/R-MMU-5693608 Initial resection of double-strand break ends IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-5693724 https://reactome.org/PathwayBrowser/#/R-MMU-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5693742 https://reactome.org/PathwayBrowser/#/R-MMU-5693742 FAAH hydrolyses AEA to AA and ETA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5693783 https://reactome.org/PathwayBrowser/#/R-MMU-5693783 NAALADases hydrolyse NAAG IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-5693807 https://reactome.org/PathwayBrowser/#/R-MMU-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694077 https://reactome.org/PathwayBrowser/#/R-MMU-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5694109 https://reactome.org/PathwayBrowser/#/R-MMU-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694126 https://reactome.org/PathwayBrowser/#/R-MMU-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5694137 https://reactome.org/PathwayBrowser/#/R-MMU-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694421 https://reactome.org/PathwayBrowser/#/R-MMU-5694421 PP6 dephosphorylates SEC24 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694485 https://reactome.org/PathwayBrowser/#/R-MMU-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5694563 https://reactome.org/PathwayBrowser/#/R-MMU-5694563 ABHD10 hydrolyses MPAG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5694583 https://reactome.org/PathwayBrowser/#/R-MMU-5694583 ABHD4 hydrolyses NAPE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5695964 https://reactome.org/PathwayBrowser/#/R-MMU-5695964 ABHD14B hydrolyses PNPB IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696049 https://reactome.org/PathwayBrowser/#/R-MMU-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5696197 https://reactome.org/PathwayBrowser/#/R-MMU-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696230 https://reactome.org/PathwayBrowser/#/R-MMU-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696365 https://reactome.org/PathwayBrowser/#/R-MMU-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5696408 https://reactome.org/PathwayBrowser/#/R-MMU-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-5696415 https://reactome.org/PathwayBrowser/#/R-MMU-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696465 https://reactome.org/PathwayBrowser/#/R-MMU-5696465 USP45 deubiquitinates ERCC1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696534 https://reactome.org/PathwayBrowser/#/R-MMU-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696564 https://reactome.org/PathwayBrowser/#/R-MMU-5696564 USP25 deubiquitinates DDX58 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696600 https://reactome.org/PathwayBrowser/#/R-MMU-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696605 https://reactome.org/PathwayBrowser/#/R-MMU-5696605 USP12, USP26 deubiquitinate AR IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696627 https://reactome.org/PathwayBrowser/#/R-MMU-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696872 https://reactome.org/PathwayBrowser/#/R-MMU-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696914 https://reactome.org/PathwayBrowser/#/R-MMU-5696914 USP28 deubiquitinates CLSPN and MYC IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696945 https://reactome.org/PathwayBrowser/#/R-MMU-5696945 USP33 deubiquitinates CCP110,ARRB IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696947 https://reactome.org/PathwayBrowser/#/R-MMU-5696947 USP47 deubiquitinates POLB IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696958 https://reactome.org/PathwayBrowser/#/R-MMU-5696958 USP44 deubiquitinates CDC20 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-5696968 https://reactome.org/PathwayBrowser/#/R-MMU-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5696997 https://reactome.org/PathwayBrowser/#/R-MMU-5696997 USP24 deubiquitinates DDB2 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-5697009 https://reactome.org/PathwayBrowser/#/R-MMU-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6781764 https://reactome.org/PathwayBrowser/#/R-MMU-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6781779 https://reactome.org/PathwayBrowser/#/R-MMU-6781779 USP13 deubiquitinates BECN1,USP10 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6781814 https://reactome.org/PathwayBrowser/#/R-MMU-6781814 USP19 deubiquitinates RNF123 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6781897 https://reactome.org/PathwayBrowser/#/R-MMU-6781897 USP11 deubiquitinates NFKBIA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6782069 https://reactome.org/PathwayBrowser/#/R-MMU-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6782106 https://reactome.org/PathwayBrowser/#/R-MMU-6782106 USP10 deubiquitinates SNX3, CFTR IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6782628 https://reactome.org/PathwayBrowser/#/R-MMU-6782628 USP8 deubiquitinates STAM2:HGS IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6782820 https://reactome.org/PathwayBrowser/#/R-MMU-6782820 USP17 deubiquitinates SUDS3 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6783177 https://reactome.org/PathwayBrowser/#/R-MMU-6783177 USP21 deubiquitinates GATA3,IL33 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6784402 https://reactome.org/PathwayBrowser/#/R-MMU-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6784959 https://reactome.org/PathwayBrowser/#/R-MMU-6784959 BPHL hydrolyses VACV to ACV IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6786190 https://reactome.org/PathwayBrowser/#/R-MMU-6786190 CMBL hydrolyses OM to OLMS IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6786295 https://reactome.org/PathwayBrowser/#/R-MMU-6786295 Dctpp1 hydrolyses 5idCTP TAS Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6786421 https://reactome.org/PathwayBrowser/#/R-MMU-6786421 CHIA hydrolyses chitin IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6786650 https://reactome.org/PathwayBrowser/#/R-MMU-6786650 DDHD1,2 hydrolyse PA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6786652 https://reactome.org/PathwayBrowser/#/R-MMU-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6787632 https://reactome.org/PathwayBrowser/#/R-MMU-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6788295 https://reactome.org/PathwayBrowser/#/R-MMU-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6788912 https://reactome.org/PathwayBrowser/#/R-MMU-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Mus musculus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6789310 https://reactome.org/PathwayBrowser/#/R-MMU-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6792445 https://reactome.org/PathwayBrowser/#/R-MMU-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6792863 https://reactome.org/PathwayBrowser/#/R-MMU-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6797627 https://reactome.org/PathwayBrowser/#/R-MMU-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6797630 https://reactome.org/PathwayBrowser/#/R-MMU-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6797653 https://reactome.org/PathwayBrowser/#/R-MMU-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6797913 https://reactome.org/PathwayBrowser/#/R-MMU-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6797955 https://reactome.org/PathwayBrowser/#/R-MMU-6797955 ALDH7A1 oxidises BETALD to BET IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6799545 https://reactome.org/PathwayBrowser/#/R-MMU-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-6799581 https://reactome.org/PathwayBrowser/#/R-MMU-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6799604 https://reactome.org/PathwayBrowser/#/R-MMU-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6799695 https://reactome.org/PathwayBrowser/#/R-MMU-6799695 GPX5,6 reduce H2O2 to H2O IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6799977 https://reactome.org/PathwayBrowser/#/R-MMU-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6800198 https://reactome.org/PathwayBrowser/#/R-MMU-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6800200 https://reactome.org/PathwayBrowser/#/R-MMU-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6800299 https://reactome.org/PathwayBrowser/#/R-MMU-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6801462 https://reactome.org/PathwayBrowser/#/R-MMU-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6803545 https://reactome.org/PathwayBrowser/#/R-MMU-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-6803753 https://reactome.org/PathwayBrowser/#/R-MMU-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6803789 https://reactome.org/PathwayBrowser/#/R-MMU-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6805650 https://reactome.org/PathwayBrowser/#/R-MMU-6805650 MTA2-NuRD complex deacetylates TP53 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6807008 https://reactome.org/PathwayBrowser/#/R-MMU-6807008 PTPRJ dephosphorylates MET IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6807027 https://reactome.org/PathwayBrowser/#/R-MMU-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6807118 https://reactome.org/PathwayBrowser/#/R-MMU-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6807206 https://reactome.org/PathwayBrowser/#/R-MMU-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-6809263 https://reactome.org/PathwayBrowser/#/R-MMU-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809320 https://reactome.org/PathwayBrowser/#/R-MMU-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809325 https://reactome.org/PathwayBrowser/#/R-MMU-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809624 https://reactome.org/PathwayBrowser/#/R-MMU-6809624 I(1,3)P2 is dephosphorylated into I1P by Mtmr7 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809627 https://reactome.org/PathwayBrowser/#/R-MMU-6809627 I(1,3)P2 is dephosphorylated into I1P by Mtmr7:Mtmr9 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809720 https://reactome.org/PathwayBrowser/#/R-MMU-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809777 https://reactome.org/PathwayBrowser/#/R-MMU-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809778 https://reactome.org/PathwayBrowser/#/R-MMU-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809945 https://reactome.org/PathwayBrowser/#/R-MMU-6809945 PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6809977 https://reactome.org/PathwayBrowser/#/R-MMU-6809977 PI3P is dephosphorylated to PI by the Mtmr2:Sbf2 tetramer at the plasma membrane TAS Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-6810410 https://reactome.org/PathwayBrowser/#/R-MMU-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-6810452 https://reactome.org/PathwayBrowser/#/R-MMU-6810452 Nudt7 hydrolyses CoA-SH to 3',5'-ADP and PPANT TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6810464 https://reactome.org/PathwayBrowser/#/R-MMU-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-6810472 https://reactome.org/PathwayBrowser/#/R-MMU-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6811504 https://reactome.org/PathwayBrowser/#/R-MMU-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6813720 https://reactome.org/PathwayBrowser/#/R-MMU-6813720 NCEH1 hydrolyzes cholesterol esters IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6813740 https://reactome.org/PathwayBrowser/#/R-MMU-6813740 GDE1 hydrolyzes GroPIns IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6814137 https://reactome.org/PathwayBrowser/#/R-MMU-6814137 Gdpd5 hydrolyzes GPCho TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-6814254 https://reactome.org/PathwayBrowser/#/R-MMU-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-6814797 https://reactome.org/PathwayBrowser/#/R-MMU-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-69199 https://reactome.org/PathwayBrowser/#/R-MMU-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70262 https://reactome.org/PathwayBrowser/#/R-MMU-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70479 https://reactome.org/PathwayBrowser/#/R-MMU-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70494 https://reactome.org/PathwayBrowser/#/R-MMU-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70569 https://reactome.org/PathwayBrowser/#/R-MMU-70569 arginine + H2O => ornithine + urea [ARG1] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70609 https://reactome.org/PathwayBrowser/#/R-MMU-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70785 https://reactome.org/PathwayBrowser/#/R-MMU-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70870 https://reactome.org/PathwayBrowser/#/R-MMU-70870 ECHS1 hydrates methacrylyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70903 https://reactome.org/PathwayBrowser/#/R-MMU-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-70906 https://reactome.org/PathwayBrowser/#/R-MMU-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-70982 https://reactome.org/PathwayBrowser/#/R-MMU-70982 FH tetramer hydrates fumarate to L-malate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71146 https://reactome.org/PathwayBrowser/#/R-MMU-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71196 https://reactome.org/PathwayBrowser/#/R-MMU-71196 N-formylkynurenine + H2O => kynurenine + formate [mouse] TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71296 https://reactome.org/PathwayBrowser/#/R-MMU-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71660 https://reactome.org/PathwayBrowser/#/R-MMU-71660 Enolase dimers dehydrates 2PG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71676 https://reactome.org/PathwayBrowser/#/R-MMU-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-71732 https://reactome.org/PathwayBrowser/#/R-MMU-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-71825 https://reactome.org/PathwayBrowser/#/R-MMU-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73608 https://reactome.org/PathwayBrowser/#/R-MMU-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73797 https://reactome.org/PathwayBrowser/#/R-MMU-73797 FAICAR => IMP + H2O IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-73815 https://reactome.org/PathwayBrowser/#/R-MMU-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74059 https://reactome.org/PathwayBrowser/#/R-MMU-74059 PDE6 hydrolyses cGMP to GMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74241 https://reactome.org/PathwayBrowser/#/R-MMU-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74248 https://reactome.org/PathwayBrowser/#/R-MMU-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74733 https://reactome.org/PathwayBrowser/#/R-MMU-74733 Insulin receptor de-phosphorylation IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-74948 https://reactome.org/PathwayBrowser/#/R-MMU-74948 PP2A dephosphorylates p-RHO to RHO IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-75899 https://reactome.org/PathwayBrowser/#/R-MMU-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-76590 https://reactome.org/PathwayBrowser/#/R-MMU-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77256 https://reactome.org/PathwayBrowser/#/R-MMU-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77277 https://reactome.org/PathwayBrowser/#/R-MMU-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77301 https://reactome.org/PathwayBrowser/#/R-MMU-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77314 https://reactome.org/PathwayBrowser/#/R-MMU-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77325 https://reactome.org/PathwayBrowser/#/R-MMU-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77333 https://reactome.org/PathwayBrowser/#/R-MMU-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-77344 https://reactome.org/PathwayBrowser/#/R-MMU-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-77614 https://reactome.org/PathwayBrowser/#/R-MMU-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-77615 https://reactome.org/PathwayBrowser/#/R-MMU-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-83677 https://reactome.org/PathwayBrowser/#/R-MMU-83677 C4 deamination of cytidine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-870437 https://reactome.org/PathwayBrowser/#/R-MMU-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-877301 https://reactome.org/PathwayBrowser/#/R-MMU-877301 Dephosphorylation of Jaks by Ptps TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8847424 https://reactome.org/PathwayBrowser/#/R-MMU-8847424 Gdpd1 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8847427 https://reactome.org/PathwayBrowser/#/R-MMU-8847427 Gdpd3 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8847904 https://reactome.org/PathwayBrowser/#/R-MMU-8847904 Pnpla7 hydrolyzes LysoPtdCho TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8848053 https://reactome.org/PathwayBrowser/#/R-MMU-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8848215 https://reactome.org/PathwayBrowser/#/R-MMU-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8848339 https://reactome.org/PathwayBrowser/#/R-MMU-8848339 PNPLA5 hydrolyzes TAG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8848484 https://reactome.org/PathwayBrowser/#/R-MMU-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8849435 https://reactome.org/PathwayBrowser/#/R-MMU-8849435 PTPN1 dephosphorylates PTK6 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8849847 https://reactome.org/PathwayBrowser/#/R-MMU-8849847 St14 hydrolyzes and activates Klk5 TAS Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8849857 https://reactome.org/PathwayBrowser/#/R-MMU-8849857 KLK5 cleaves and activates CELA2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8849969 https://reactome.org/PathwayBrowser/#/R-MMU-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8850594 https://reactome.org/PathwayBrowser/#/R-MMU-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8850831 https://reactome.org/PathwayBrowser/#/R-MMU-8850831 KLK5 cleaves and activates KLK8 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-2022884 H2O [Golgi lumen] R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-2022884 H2O [Golgi lumen] R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8852200 https://reactome.org/PathwayBrowser/#/R-MMU-8852200 Inactivation of LCK by PTPN22 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8853379 https://reactome.org/PathwayBrowser/#/R-MMU-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-8853686 https://reactome.org/PathwayBrowser/#/R-MMU-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8854173 https://reactome.org/PathwayBrowser/#/R-MMU-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8854255 https://reactome.org/PathwayBrowser/#/R-MMU-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8854329 https://reactome.org/PathwayBrowser/#/R-MMU-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8854604 https://reactome.org/PathwayBrowser/#/R-MMU-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8854612 https://reactome.org/PathwayBrowser/#/R-MMU-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8855381 https://reactome.org/PathwayBrowser/#/R-MMU-8855381 PTPN22 dephosphorylates ZAP70 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8855490 https://reactome.org/PathwayBrowser/#/R-MMU-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8855825 https://reactome.org/PathwayBrowser/#/R-MMU-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-8856951 https://reactome.org/PathwayBrowser/#/R-MMU-8856951 PP2A demethylation by PPME1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-8862184 https://reactome.org/PathwayBrowser/#/R-MMU-8862184 USP48 cleaves polyubiquitin IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8862320 https://reactome.org/PathwayBrowser/#/R-MMU-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8863416 https://reactome.org/PathwayBrowser/#/R-MMU-8863416 Calpain 1 or Calpain 2 cleaves Cdk5r1 (p35) TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8863804 https://reactome.org/PathwayBrowser/#/R-MMU-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8864029 https://reactome.org/PathwayBrowser/#/R-MMU-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8864036 https://reactome.org/PathwayBrowser/#/R-MMU-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8864125 https://reactome.org/PathwayBrowser/#/R-MMU-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-8865667 https://reactome.org/PathwayBrowser/#/R-MMU-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8866405 https://reactome.org/PathwayBrowser/#/R-MMU-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8866542 https://reactome.org/PathwayBrowser/#/R-MMU-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8867047 https://reactome.org/PathwayBrowser/#/R-MMU-8867047 PTPN3 dephosphorylates EPS15 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-8867344 https://reactome.org/PathwayBrowser/#/R-MMU-8867344 OMA1 hydrolyses OPA1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8867658 https://reactome.org/PathwayBrowser/#/R-MMU-8867658 PTPN3 dephosphorylates MAPK12 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8868648 https://reactome.org/PathwayBrowser/#/R-MMU-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8868658 https://reactome.org/PathwayBrowser/#/R-MMU-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8868661 https://reactome.org/PathwayBrowser/#/R-MMU-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8869206 https://reactome.org/PathwayBrowser/#/R-MMU-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8869425 https://reactome.org/PathwayBrowser/#/R-MMU-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8869456 https://reactome.org/PathwayBrowser/#/R-MMU-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8869506 https://reactome.org/PathwayBrowser/#/R-MMU-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8874435 https://reactome.org/PathwayBrowser/#/R-MMU-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8875443 https://reactome.org/PathwayBrowser/#/R-MMU-8875443 USP8 deubiquitinates LRIG1 IEA Mus musculus 15377 R-ALL-5668574 H2O [melanosome lumen] R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-8878654 https://reactome.org/PathwayBrowser/#/R-MMU-8878654 ACP6 hydrolyses MYS-LPA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8878787 https://reactome.org/PathwayBrowser/#/R-MMU-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8932633 https://reactome.org/PathwayBrowser/#/R-MMU-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8933328 https://reactome.org/PathwayBrowser/#/R-MMU-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Mus musculus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-893596 https://reactome.org/PathwayBrowser/#/R-MMU-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8937442 https://reactome.org/PathwayBrowser/#/R-MMU-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-8937767 https://reactome.org/PathwayBrowser/#/R-MMU-8937767 PTPN11 dephosphorylates RUNX1 IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8940074 https://reactome.org/PathwayBrowser/#/R-MMU-8940074 NT5E:Zn2+ hydrolyses NMN IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8940388 https://reactome.org/PathwayBrowser/#/R-MMU-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8943279 https://reactome.org/PathwayBrowser/#/R-MMU-8943279 GGT dimers hydrolyse GSH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8952137 https://reactome.org/PathwayBrowser/#/R-MMU-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8952251 https://reactome.org/PathwayBrowser/#/R-MMU-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-8952903 https://reactome.org/PathwayBrowser/#/R-MMU-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8953339 https://reactome.org/PathwayBrowser/#/R-MMU-8953339 DNPH1 hydrolyses dGMP IEA Mus musculus 15377 R-ALL-2022884 H2O [Golgi lumen] R-MMU-8953499 https://reactome.org/PathwayBrowser/#/R-MMU-8953499 IMPAD1 hydrolyses PAP to AMP IEA Mus musculus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-MMU-8954398 https://reactome.org/PathwayBrowser/#/R-MMU-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8955794 https://reactome.org/PathwayBrowser/#/R-MMU-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-8955817 https://reactome.org/PathwayBrowser/#/R-MMU-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8979996 https://reactome.org/PathwayBrowser/#/R-MMU-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-8980228 https://reactome.org/PathwayBrowser/#/R-MMU-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8981637 https://reactome.org/PathwayBrowser/#/R-MMU-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8985594 https://reactome.org/PathwayBrowser/#/R-MMU-8985594 MYO9B inactivates RHOA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-8986083 https://reactome.org/PathwayBrowser/#/R-MMU-8986083 USP33 deubiquitinates ROBO1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-9008822 https://reactome.org/PathwayBrowser/#/R-MMU-9008822 PPM1D dephosphorylates RUNX2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9013022 https://reactome.org/PathwayBrowser/#/R-MMU-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9013111 https://reactome.org/PathwayBrowser/#/R-MMU-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9013144 https://reactome.org/PathwayBrowser/#/R-MMU-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9013161 https://reactome.org/PathwayBrowser/#/R-MMU-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9013437 https://reactome.org/PathwayBrowser/#/R-MMU-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9014295 https://reactome.org/PathwayBrowser/#/R-MMU-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9014434 https://reactome.org/PathwayBrowser/#/R-MMU-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9014641 https://reactome.org/PathwayBrowser/#/R-MMU-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9017488 https://reactome.org/PathwayBrowser/#/R-MMU-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018745 https://reactome.org/PathwayBrowser/#/R-MMU-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018806 https://reactome.org/PathwayBrowser/#/R-MMU-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018814 https://reactome.org/PathwayBrowser/#/R-MMU-9018814 RHOT1 hydrolyzes GTP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018826 https://reactome.org/PathwayBrowser/#/R-MMU-9018826 RHOT2 hydrolyzes GTP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018862 https://reactome.org/PathwayBrowser/#/R-MMU-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018868 https://reactome.org/PathwayBrowser/#/R-MMU-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018877 https://reactome.org/PathwayBrowser/#/R-MMU-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9018895 https://reactome.org/PathwayBrowser/#/R-MMU-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020252 https://reactome.org/PathwayBrowser/#/R-MMU-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020253 https://reactome.org/PathwayBrowser/#/R-MMU-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020257 https://reactome.org/PathwayBrowser/#/R-MMU-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020258 https://reactome.org/PathwayBrowser/#/R-MMU-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020270 https://reactome.org/PathwayBrowser/#/R-MMU-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020271 https://reactome.org/PathwayBrowser/#/R-MMU-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9020273 https://reactome.org/PathwayBrowser/#/R-MMU-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9024890 https://reactome.org/PathwayBrowser/#/R-MMU-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9024993 https://reactome.org/PathwayBrowser/#/R-MMU-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9032476 https://reactome.org/PathwayBrowser/#/R-MMU-9032476 Epor-associated Plcg hydrolyzes 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9033491 https://reactome.org/PathwayBrowser/#/R-MMU-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9033520 https://reactome.org/PathwayBrowser/#/R-MMU-9033520 TYSND1 cleaves TYSND1 IEA Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9033995 https://reactome.org/PathwayBrowser/#/R-MMU-9033995 Tysnd1 cleaves Agps TAS Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9034001 https://reactome.org/PathwayBrowser/#/R-MMU-9034001 Tysnd1 cleaves Phyh TAS Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9034335 https://reactome.org/PathwayBrowser/#/R-MMU-9034335 Tysnd1 cleaves Scp2 TAS Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9034351 https://reactome.org/PathwayBrowser/#/R-MMU-9034351 Tysnd1 cleaves Hsd17b4 TAS Mus musculus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-MMU-9034356 https://reactome.org/PathwayBrowser/#/R-MMU-9034356 Tysnd1 cleaves Acaa1a TAS Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9036727 https://reactome.org/PathwayBrowser/#/R-MMU-9036727 GAA hydrolyzes lysosomal glycogen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-936802 https://reactome.org/PathwayBrowser/#/R-MMU-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-936883 https://reactome.org/PathwayBrowser/#/R-MMU-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-936895 https://reactome.org/PathwayBrowser/#/R-MMU-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-936897 https://reactome.org/PathwayBrowser/#/R-MMU-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-939763 https://reactome.org/PathwayBrowser/#/R-MMU-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-947531 https://reactome.org/PathwayBrowser/#/R-MMU-947531 Molybdenum ion transfer onto molybdopterin IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-947535 https://reactome.org/PathwayBrowser/#/R-MMU-947535 Cyclisation of GTP to precursor Z IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-947591 https://reactome.org/PathwayBrowser/#/R-MMU-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9624893 https://reactome.org/PathwayBrowser/#/R-MMU-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9629675 https://reactome.org/PathwayBrowser/#/R-MMU-9629675 PDE3A hydrolyses cAMP to AMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9635739 https://reactome.org/PathwayBrowser/#/R-MMU-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9638046 https://reactome.org/PathwayBrowser/#/R-MMU-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9638075 https://reactome.org/PathwayBrowser/#/R-MMU-9638075 HEXB cleaves the terminal GalNAc from DS IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9638076 https://reactome.org/PathwayBrowser/#/R-MMU-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9638078 https://reactome.org/PathwayBrowser/#/R-MMU-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9638120 https://reactome.org/PathwayBrowser/#/R-MMU-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9644869 https://reactome.org/PathwayBrowser/#/R-MMU-9644869 p-S54-PDE4B hydrolyses cAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9647994 https://reactome.org/PathwayBrowser/#/R-MMU-9647994 RAS proteins are depalmitoylated IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-965067 https://reactome.org/PathwayBrowser/#/R-MMU-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9653514 https://reactome.org/PathwayBrowser/#/R-MMU-9653514 USP17L2 deubiquitinates RCE1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9656891 https://reactome.org/PathwayBrowser/#/R-MMU-9656891 OPN1SW binds 11cRAL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9656893 https://reactome.org/PathwayBrowser/#/R-MMU-9656893 OPN1MW binds 11cRAL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9658445 https://reactome.org/PathwayBrowser/#/R-MMU-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9659680 https://reactome.org/PathwayBrowser/#/R-MMU-9659680 ABCB1 transports xenobiotics out of the cell IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9661417 https://reactome.org/PathwayBrowser/#/R-MMU-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9667952 https://reactome.org/PathwayBrowser/#/R-MMU-9667952 ANKLE2 is deacetylated by SIRT2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9668419 https://reactome.org/PathwayBrowser/#/R-MMU-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-9673053 https://reactome.org/PathwayBrowser/#/R-MMU-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-9673054 https://reactome.org/PathwayBrowser/#/R-MMU-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9674127 https://reactome.org/PathwayBrowser/#/R-MMU-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9682158 https://reactome.org/PathwayBrowser/#/R-MMU-9682158 Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol TAS Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-9686524 https://reactome.org/PathwayBrowser/#/R-MMU-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9693282 https://reactome.org/PathwayBrowser/#/R-MMU-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9698408 https://reactome.org/PathwayBrowser/#/R-MMU-9698408 PTPRJ dephosphorylates active FLT3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9700200 https://reactome.org/PathwayBrowser/#/R-MMU-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9701507 https://reactome.org/PathwayBrowser/#/R-MMU-9701507 PTPN6 dephosphorylates JAK3 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-9701565 https://reactome.org/PathwayBrowser/#/R-MMU-9701565 HDACs deacetylate p-STAT3 dimers IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9705507 https://reactome.org/PathwayBrowser/#/R-MMU-9705507 PDE3B hydrolyses cAMP to AMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9706399 https://reactome.org/PathwayBrowser/#/R-MMU-9706399 RHOBTB3 hydrolyzes ATP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9708261 https://reactome.org/PathwayBrowser/#/R-MMU-9708261 PDE4A hydrolyses cAMP to AMP IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9727567 https://reactome.org/PathwayBrowser/#/R-MMU-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9750546 https://reactome.org/PathwayBrowser/#/R-MMU-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9750555 https://reactome.org/PathwayBrowser/#/R-MMU-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9750617 https://reactome.org/PathwayBrowser/#/R-MMU-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9750656 https://reactome.org/PathwayBrowser/#/R-MMU-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9750942 https://reactome.org/PathwayBrowser/#/R-MMU-9750942 USP14 deubiquitinates NLRC5 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753278 https://reactome.org/PathwayBrowser/#/R-MMU-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753280 https://reactome.org/PathwayBrowser/#/R-MMU-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753283 https://reactome.org/PathwayBrowser/#/R-MMU-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753284 https://reactome.org/PathwayBrowser/#/R-MMU-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753632 https://reactome.org/PathwayBrowser/#/R-MMU-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753634 https://reactome.org/PathwayBrowser/#/R-MMU-9753634 GGT dimers hydrolyse APAP-SG IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9753944 https://reactome.org/PathwayBrowser/#/R-MMU-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9754964 https://reactome.org/PathwayBrowser/#/R-MMU-9754964 ADA deamidates RBV IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9755030 https://reactome.org/PathwayBrowser/#/R-MMU-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9755078 https://reactome.org/PathwayBrowser/#/R-MMU-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-975593 https://reactome.org/PathwayBrowser/#/R-MMU-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Mus musculus 15377 R-ALL-109276 H2O [extracellular region] R-MMU-975594 https://reactome.org/PathwayBrowser/#/R-MMU-975594 PLB1 hydrolyses RPALM to atROL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9759206 https://reactome.org/PathwayBrowser/#/R-MMU-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9759454 https://reactome.org/PathwayBrowser/#/R-MMU-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9759461 https://reactome.org/PathwayBrowser/#/R-MMU-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-977324 https://reactome.org/PathwayBrowser/#/R-MMU-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9794120 https://reactome.org/PathwayBrowser/#/R-MMU-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9794572 https://reactome.org/PathwayBrowser/#/R-MMU-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-9825772 https://reactome.org/PathwayBrowser/#/R-MMU-9825772 SIRT1 deacetylates HINT1 dimer IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-983144 https://reactome.org/PathwayBrowser/#/R-MMU-983144 Transport of Antigen peptide in to ER IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-983422 https://reactome.org/PathwayBrowser/#/R-MMU-983422 Disassembly of COPII coated vesicle IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9837419 https://reactome.org/PathwayBrowser/#/R-MMU-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9838004 https://reactome.org/PathwayBrowser/#/R-MMU-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9838081 https://reactome.org/PathwayBrowser/#/R-MMU-9838081 LONP1 degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9838289 https://reactome.org/PathwayBrowser/#/R-MMU-9838289 CLPXP degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9839059 https://reactome.org/PathwayBrowser/#/R-MMU-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Mus musculus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-MMU-9839072 https://reactome.org/PathwayBrowser/#/R-MMU-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9839105 https://reactome.org/PathwayBrowser/#/R-MMU-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Mus musculus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-MMU-9839110 https://reactome.org/PathwayBrowser/#/R-MMU-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9839113 https://reactome.org/PathwayBrowser/#/R-MMU-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Mus musculus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-MMU-9840408 https://reactome.org/PathwayBrowser/#/R-MMU-9840408 OMA1 cleaves DELE1 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9840795 https://reactome.org/PathwayBrowser/#/R-MMU-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9840833 https://reactome.org/PathwayBrowser/#/R-MMU-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9840884 https://reactome.org/PathwayBrowser/#/R-MMU-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9840949 https://reactome.org/PathwayBrowser/#/R-MMU-9840949 ARSA removes sulfate from SM3 IEA Mus musculus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-MMU-9841189 https://reactome.org/PathwayBrowser/#/R-MMU-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9841847 https://reactome.org/PathwayBrowser/#/R-MMU-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9853385 https://reactome.org/PathwayBrowser/#/R-MMU-9853385 PPP1CC dephosphorylates PLK1 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9861626 https://reactome.org/PathwayBrowser/#/R-MMU-9861626 SIRT4 cleaves lipoyl from DLAT IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9861725 https://reactome.org/PathwayBrowser/#/R-MMU-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9865167 https://reactome.org/PathwayBrowser/#/R-MMU-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9865226 https://reactome.org/PathwayBrowser/#/R-MMU-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9912636 https://reactome.org/PathwayBrowser/#/R-MMU-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9912655 https://reactome.org/PathwayBrowser/#/R-MMU-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9912747 https://reactome.org/PathwayBrowser/#/R-MMU-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9912751 https://reactome.org/PathwayBrowser/#/R-MMU-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9915968 https://reactome.org/PathwayBrowser/#/R-MMU-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9915971 https://reactome.org/PathwayBrowser/#/R-MMU-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9915986 https://reactome.org/PathwayBrowser/#/R-MMU-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-MMU-9915993 https://reactome.org/PathwayBrowser/#/R-MMU-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9915994 https://reactome.org/PathwayBrowser/#/R-MMU-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9915997 https://reactome.org/PathwayBrowser/#/R-MMU-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-9916401 https://reactome.org/PathwayBrowser/#/R-MMU-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Mus musculus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-MMU-9929439 https://reactome.org/PathwayBrowser/#/R-MMU-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-997309 https://reactome.org/PathwayBrowser/#/R-MMU-997309 Dephosphorylation of STAT1 by SHP2 IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-997311 https://reactome.org/PathwayBrowser/#/R-MMU-997311 Dephosphorylation of TYK2 by PTP1B IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MMU-997314 https://reactome.org/PathwayBrowser/#/R-MMU-997314 Dephosphorylation of JAK1 by SHP1 IEA Mus musculus 15377 R-ALL-113518 H2O [nucleoplasm] R-MMU-997326 https://reactome.org/PathwayBrowser/#/R-MMU-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-MTU-868608 https://reactome.org/PathwayBrowser/#/R-MTU-868608 Trehalose-6-phosphate is hydrolyzed to trehalose TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-868657 https://reactome.org/PathwayBrowser/#/R-MTU-868657 Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879274 https://reactome.org/PathwayBrowser/#/R-MTU-879274 acetylglucosamine-inositol-phosphate is dephosphorylated TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879281 https://reactome.org/PathwayBrowser/#/R-MTU-879281 mycothiol is cleaved to acetylcysteine and glucosaminylinositol TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879298 https://reactome.org/PathwayBrowser/#/R-MTU-879298 acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879311 https://reactome.org/PathwayBrowser/#/R-MTU-879311 mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-879327 https://reactome.org/PathwayBrowser/#/R-MTU-879327 acetylglucosamine-inositol is deacetylated by Mca TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-936631 https://reactome.org/PathwayBrowser/#/R-MTU-936631 sulfate uptake in the cytosol TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-936659 https://reactome.org/PathwayBrowser/#/R-MTU-936659 PAPS is dephosphorylated to APS TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-936747 https://reactome.org/PathwayBrowser/#/R-MTU-936747 cleavage of L-cysteine from carrier protein TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-937192 https://reactome.org/PathwayBrowser/#/R-MTU-937192 Cysteine from cystathionine and vice versa TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-964851 https://reactome.org/PathwayBrowser/#/R-MTU-964851 Dehydratation of DHQ yields DHS TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-MTU-964912 https://reactome.org/PathwayBrowser/#/R-MTU-964912 DHAP from Ery4P and PEP TAS Mycobacterium tuberculosis 15377 R-ALL-29356 H2O [cytosol] R-NUL-1236944 https://reactome.org/PathwayBrowser/#/R-NUL-1236944 Translocation of antigenic peptides back to phagosomes via TAP TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-NUL-2167872 https://reactome.org/PathwayBrowser/#/R-NUL-2167872 PP1CC dephosphorylates TGFBR1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-NUL-2179313 https://reactome.org/PathwayBrowser/#/R-NUL-2179313 Uchl5 deubiquitinates TGFBR1 TAS Homo sapiens 15377 R-ALL-29356 H2O [cytosol] R-NUL-8955728 https://reactome.org/PathwayBrowser/#/R-NUL-8955728 TTCP hydrolyzes the terminal L-Tyr residue from alpha-tubulin TAS Bos taurus 15377 R-ALL-351603 H2O [secretory granule lumen] R-NUL-9023165 https://reactome.org/PathwayBrowser/#/R-NUL-9023165 Pcsk1 (rat) cleaves human proinsulin to yield Insulin(25-56) and Insulin(57-110) TAS Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-NUL-9023166 https://reactome.org/PathwayBrowser/#/R-NUL-9023166 Carboxypeptidase E (rat Carboxypeptidase H) cleaves Insulin(25-56) to yield Insulin(25-54) TAS Homo sapiens 15377 R-ALL-351603 H2O [secretory granule lumen] R-NUL-9023180 https://reactome.org/PathwayBrowser/#/R-NUL-9023180 Pcsk2 (rat) cleaves human Insulin(57-110) to yield Insulin(90-110) and C-peptide (Insulin(57-89)) TAS Homo sapiens 15377 R-ALL-141343 H2O [peroxisomal matrix] R-NUL-9034341 https://reactome.org/PathwayBrowser/#/R-NUL-9034341 Tysnd1 cleaves Acox1 TAS Mus musculus 15377 R-ALL-29356 H2O [cytosol] R-NUL-9603754 https://reactome.org/PathwayBrowser/#/R-NUL-9603754 PTPRS dephosphorylates Ntrk3 TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-NUL-9603766 https://reactome.org/PathwayBrowser/#/R-NUL-9603766 PTPRO dephosphorylate NTRK3 TAS Gallus gallus 15377 R-ALL-29356 H2O [cytosol] R-NUL-9717576 https://reactome.org/PathwayBrowser/#/R-NUL-9717576 Gnb1:GNG2:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG TAS Bos taurus 15377 R-ALL-109276 H2O [extracellular region] R-OCU-189019 https://reactome.org/PathwayBrowser/#/R-OCU-189019 trehalose + H2O => 2 D-glucose TAS Oryctolagus cuniculus 15377 R-ALL-29356 H2O [cytosol] R-OCU-2161896 https://reactome.org/PathwayBrowser/#/R-OCU-2161896 5S-HpETE is reduced to 5S-HETE by GPX1 TAS Oryctolagus cuniculus 15377 R-ALL-29356 H2O [cytosol] R-PFA-111742 https://reactome.org/PathwayBrowser/#/R-PFA-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-111751 https://reactome.org/PathwayBrowser/#/R-PFA-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-111804 https://reactome.org/PathwayBrowser/#/R-PFA-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-111955 https://reactome.org/PathwayBrowser/#/R-PFA-111955 cAMP hydrolysis by Cam-PDE 1 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-111962 https://reactome.org/PathwayBrowser/#/R-PFA-111962 PDE4A,C,D hydrolyse cAMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1369028 https://reactome.org/PathwayBrowser/#/R-PFA-1369028 ABCAs mediate lipid efflux IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1369052 https://reactome.org/PathwayBrowser/#/R-PFA-1369052 ABCAs mediate lipid influx IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1369065 https://reactome.org/PathwayBrowser/#/R-PFA-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1454916 https://reactome.org/PathwayBrowser/#/R-PFA-1454916 The ABCC family mediates organic anion transport IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1467457 https://reactome.org/PathwayBrowser/#/R-PFA-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1467466 https://reactome.org/PathwayBrowser/#/R-PFA-1467466 ABCA4 mediates atRAL transport IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1482543 https://reactome.org/PathwayBrowser/#/R-PFA-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1482777 https://reactome.org/PathwayBrowser/#/R-PFA-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1482811 https://reactome.org/PathwayBrowser/#/R-PFA-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1483203 https://reactome.org/PathwayBrowser/#/R-PFA-1483203 PA is dephosphorylated to DAG by LPIN IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-162425 https://reactome.org/PathwayBrowser/#/R-PFA-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-162857 https://reactome.org/PathwayBrowser/#/R-PFA-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1675824 https://reactome.org/PathwayBrowser/#/R-PFA-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1675836 https://reactome.org/PathwayBrowser/#/R-PFA-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1675949 https://reactome.org/PathwayBrowser/#/R-PFA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1675988 https://reactome.org/PathwayBrowser/#/R-PFA-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1675994 https://reactome.org/PathwayBrowser/#/R-PFA-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1676114 https://reactome.org/PathwayBrowser/#/R-PFA-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1676124 https://reactome.org/PathwayBrowser/#/R-PFA-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1676177 https://reactome.org/PathwayBrowser/#/R-PFA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1676203 https://reactome.org/PathwayBrowser/#/R-PFA-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-174391 https://reactome.org/PathwayBrowser/#/R-PFA-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855174 https://reactome.org/PathwayBrowser/#/R-PFA-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855177 https://reactome.org/PathwayBrowser/#/R-PFA-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855213 https://reactome.org/PathwayBrowser/#/R-PFA-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855214 https://reactome.org/PathwayBrowser/#/R-PFA-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855218 https://reactome.org/PathwayBrowser/#/R-PFA-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855221 https://reactome.org/PathwayBrowser/#/R-PFA-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-1855222 https://reactome.org/PathwayBrowser/#/R-PFA-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-189406 https://reactome.org/PathwayBrowser/#/R-PFA-189406 4 PBGs bind to form HMB IEA Plasmodium falciparum 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-193362 https://reactome.org/PathwayBrowser/#/R-PFA-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-196950 https://reactome.org/PathwayBrowser/#/R-PFA-196950 2xTRAP hydrolyzes FMN to RIB IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-197186 https://reactome.org/PathwayBrowser/#/R-PFA-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-200661 https://reactome.org/PathwayBrowser/#/R-PFA-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-200740 https://reactome.org/PathwayBrowser/#/R-PFA-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-201035 https://reactome.org/PathwayBrowser/#/R-PFA-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-202407 https://reactome.org/PathwayBrowser/#/R-PFA-202407 PLC-gamma1 hydrolyses PIP2 IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-203797 https://reactome.org/PathwayBrowser/#/R-PFA-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Plasmodium falciparum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-PFA-2046088 https://reactome.org/PathwayBrowser/#/R-PFA-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Plasmodium falciparum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-PFA-2046094 https://reactome.org/PathwayBrowser/#/R-PFA-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2161959 https://reactome.org/PathwayBrowser/#/R-PFA-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2161961 https://reactome.org/PathwayBrowser/#/R-PFA-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2161999 https://reactome.org/PathwayBrowser/#/R-PFA-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2408551 https://reactome.org/PathwayBrowser/#/R-PFA-2408551 SeMet is converted to AdoSeMet by MAT IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-2529015 https://reactome.org/PathwayBrowser/#/R-PFA-2529015 Dephosphorylation of CK2-modified condensin I IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-265783 https://reactome.org/PathwayBrowser/#/R-PFA-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-2995330 https://reactome.org/PathwayBrowser/#/R-PFA-2995330 COX10 transforms heme to heme O IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-2995334 https://reactome.org/PathwayBrowser/#/R-PFA-2995334 COX15 transforms heme O to heme A IEA Plasmodium falciparum 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-PFA-3341296 https://reactome.org/PathwayBrowser/#/R-PFA-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-3341343 https://reactome.org/PathwayBrowser/#/R-PFA-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-3343700 https://reactome.org/PathwayBrowser/#/R-PFA-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-3697882 https://reactome.org/PathwayBrowser/#/R-PFA-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-3782637 https://reactome.org/PathwayBrowser/#/R-PFA-3782637 HDAC8 deacetylates histones IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-3782655 https://reactome.org/PathwayBrowser/#/R-PFA-3782655 HDAC10 deacetylates histone IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-383190 https://reactome.org/PathwayBrowser/#/R-PFA-383190 HCO3- transport through ion channel IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-418553 https://reactome.org/PathwayBrowser/#/R-PFA-418553 cAMP degradation by Phosphodiesterases IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-429860 https://reactome.org/PathwayBrowser/#/R-PFA-429860 DCP1-DCP2 complex decaps mRNA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-432010 https://reactome.org/PathwayBrowser/#/R-PFA-432010 Aquaporin-1 passively transports water into cell IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-432010 https://reactome.org/PathwayBrowser/#/R-PFA-432010 Aquaporin-1 passively transports water into cell IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-432054 https://reactome.org/PathwayBrowser/#/R-PFA-432054 Aquaporin-1 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-432054 https://reactome.org/PathwayBrowser/#/R-PFA-432054 Aquaporin-1 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-432065 https://reactome.org/PathwayBrowser/#/R-PFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-432065 https://reactome.org/PathwayBrowser/#/R-PFA-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-432067 https://reactome.org/PathwayBrowser/#/R-PFA-432067 Aquaporin-4 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-432067 https://reactome.org/PathwayBrowser/#/R-PFA-432067 Aquaporin-4 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-445714 https://reactome.org/PathwayBrowser/#/R-PFA-445714 Aquaporin-3 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-445714 https://reactome.org/PathwayBrowser/#/R-PFA-445714 Aquaporin-3 passively transports water out of cell IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-449937 https://reactome.org/PathwayBrowser/#/R-PFA-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-452036 https://reactome.org/PathwayBrowser/#/R-PFA-452036 arginine + H2O => ornithine + urea [ARG2] IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-507868 https://reactome.org/PathwayBrowser/#/R-PFA-507868 Aquaporins passively transport water into cells IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-507868 https://reactome.org/PathwayBrowser/#/R-PFA-507868 Aquaporins passively transport water into cells IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-507870 https://reactome.org/PathwayBrowser/#/R-PFA-507870 Aquaporins passively transport water out of cells IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-507870 https://reactome.org/PathwayBrowser/#/R-PFA-507870 Aquaporins passively transport water out of cells IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-5221130 https://reactome.org/PathwayBrowser/#/R-PFA-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5251959 https://reactome.org/PathwayBrowser/#/R-PFA-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5251989 https://reactome.org/PathwayBrowser/#/R-PFA-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5607735 https://reactome.org/PathwayBrowser/#/R-PFA-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-5653786 https://reactome.org/PathwayBrowser/#/R-PFA-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5675373 https://reactome.org/PathwayBrowser/#/R-PFA-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5675376 https://reactome.org/PathwayBrowser/#/R-PFA-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5675433 https://reactome.org/PathwayBrowser/#/R-PFA-5675433 PP5 dephosphorylates RAF1 S338 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5676637 https://reactome.org/PathwayBrowser/#/R-PFA-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5678706 https://reactome.org/PathwayBrowser/#/R-PFA-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5678863 https://reactome.org/PathwayBrowser/#/R-PFA-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5682285 https://reactome.org/PathwayBrowser/#/R-PFA-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5683714 https://reactome.org/PathwayBrowser/#/R-PFA-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5688797 https://reactome.org/PathwayBrowser/#/R-PFA-5688797 ATXN3 family cleave Ub chains IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5688837 https://reactome.org/PathwayBrowser/#/R-PFA-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-5690066 https://reactome.org/PathwayBrowser/#/R-PFA-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5690319 https://reactome.org/PathwayBrowser/#/R-PFA-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5690808 https://reactome.org/PathwayBrowser/#/R-PFA-5690808 UCHL3, SENP8 cleave NEDD8 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5691512 https://reactome.org/PathwayBrowser/#/R-PFA-5691512 APEH hydrolyses NAc-Ser-protein IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5692462 https://reactome.org/PathwayBrowser/#/R-PFA-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5692480 https://reactome.org/PathwayBrowser/#/R-PFA-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-5694137 https://reactome.org/PathwayBrowser/#/R-PFA-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-5696197 https://reactome.org/PathwayBrowser/#/R-PFA-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-5696627 https://reactome.org/PathwayBrowser/#/R-PFA-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-6786421 https://reactome.org/PathwayBrowser/#/R-PFA-6786421 CHIA hydrolyses chitin IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-6786650 https://reactome.org/PathwayBrowser/#/R-PFA-6786650 DDHD1,2 hydrolyse PA IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-6786652 https://reactome.org/PathwayBrowser/#/R-PFA-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-6787632 https://reactome.org/PathwayBrowser/#/R-PFA-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-6789310 https://reactome.org/PathwayBrowser/#/R-PFA-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-6801462 https://reactome.org/PathwayBrowser/#/R-PFA-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-70494 https://reactome.org/PathwayBrowser/#/R-PFA-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-70569 https://reactome.org/PathwayBrowser/#/R-PFA-70569 arginine + H2O => ornithine + urea [ARG1] IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-70785 https://reactome.org/PathwayBrowser/#/R-PFA-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-71146 https://reactome.org/PathwayBrowser/#/R-PFA-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-71660 https://reactome.org/PathwayBrowser/#/R-PFA-71660 Enolase dimers dehydrates 2PG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-71732 https://reactome.org/PathwayBrowser/#/R-PFA-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-74241 https://reactome.org/PathwayBrowser/#/R-PFA-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-75899 https://reactome.org/PathwayBrowser/#/R-PFA-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-76590 https://reactome.org/PathwayBrowser/#/R-PFA-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8848053 https://reactome.org/PathwayBrowser/#/R-PFA-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8848215 https://reactome.org/PathwayBrowser/#/R-PFA-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8848338 https://reactome.org/PathwayBrowser/#/R-PFA-8848338 PNPLA4 hydrolyzes TAG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8848339 https://reactome.org/PathwayBrowser/#/R-PFA-8848339 PNPLA5 hydrolyzes TAG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8848355 https://reactome.org/PathwayBrowser/#/R-PFA-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8849969 https://reactome.org/PathwayBrowser/#/R-PFA-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8854255 https://reactome.org/PathwayBrowser/#/R-PFA-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8854329 https://reactome.org/PathwayBrowser/#/R-PFA-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8866405 https://reactome.org/PathwayBrowser/#/R-PFA-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Plasmodium falciparum 15377 R-ALL-113518 H2O [nucleoplasm] R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-PFA-8979996 https://reactome.org/PathwayBrowser/#/R-PFA-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9018868 https://reactome.org/PathwayBrowser/#/R-PFA-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9018895 https://reactome.org/PathwayBrowser/#/R-PFA-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9020271 https://reactome.org/PathwayBrowser/#/R-PFA-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9020273 https://reactome.org/PathwayBrowser/#/R-PFA-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9024993 https://reactome.org/PathwayBrowser/#/R-PFA-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-936883 https://reactome.org/PathwayBrowser/#/R-PFA-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-936895 https://reactome.org/PathwayBrowser/#/R-PFA-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-939763 https://reactome.org/PathwayBrowser/#/R-PFA-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-947591 https://reactome.org/PathwayBrowser/#/R-PFA-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9629675 https://reactome.org/PathwayBrowser/#/R-PFA-9629675 PDE3A hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9644869 https://reactome.org/PathwayBrowser/#/R-PFA-9644869 p-S54-PDE4B hydrolyses cAMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9659680 https://reactome.org/PathwayBrowser/#/R-PFA-9659680 ABCB1 transports xenobiotics out of the cell IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9661417 https://reactome.org/PathwayBrowser/#/R-PFA-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9705507 https://reactome.org/PathwayBrowser/#/R-PFA-9705507 PDE3B hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9708261 https://reactome.org/PathwayBrowser/#/R-PFA-9708261 PDE4A hydrolyses cAMP to AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9750546 https://reactome.org/PathwayBrowser/#/R-PFA-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9753278 https://reactome.org/PathwayBrowser/#/R-PFA-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9753280 https://reactome.org/PathwayBrowser/#/R-PFA-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9753283 https://reactome.org/PathwayBrowser/#/R-PFA-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9753284 https://reactome.org/PathwayBrowser/#/R-PFA-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9754964 https://reactome.org/PathwayBrowser/#/R-PFA-9754964 ADA deamidates RBV IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9755030 https://reactome.org/PathwayBrowser/#/R-PFA-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9759454 https://reactome.org/PathwayBrowser/#/R-PFA-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9759461 https://reactome.org/PathwayBrowser/#/R-PFA-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9794120 https://reactome.org/PathwayBrowser/#/R-PFA-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9794572 https://reactome.org/PathwayBrowser/#/R-PFA-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9837419 https://reactome.org/PathwayBrowser/#/R-PFA-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Plasmodium falciparum 15377 R-ALL-113521 H2O [mitochondrial matrix] R-PFA-9839105 https://reactome.org/PathwayBrowser/#/R-PFA-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9853385 https://reactome.org/PathwayBrowser/#/R-PFA-9853385 PPP1CC dephosphorylates PLK1 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9912636 https://reactome.org/PathwayBrowser/#/R-PFA-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9912655 https://reactome.org/PathwayBrowser/#/R-PFA-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9912747 https://reactome.org/PathwayBrowser/#/R-PFA-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9912751 https://reactome.org/PathwayBrowser/#/R-PFA-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9915968 https://reactome.org/PathwayBrowser/#/R-PFA-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9915986 https://reactome.org/PathwayBrowser/#/R-PFA-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Plasmodium falciparum 15377 R-ALL-29356 H2O [cytosol] R-PFA-9915994 https://reactome.org/PathwayBrowser/#/R-PFA-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Plasmodium falciparum 15377 R-ALL-109276 H2O [extracellular region] R-RNO-109278 https://reactome.org/PathwayBrowser/#/R-RNO-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-109291 https://reactome.org/PathwayBrowser/#/R-RNO-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109380 https://reactome.org/PathwayBrowser/#/R-RNO-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109387 https://reactome.org/PathwayBrowser/#/R-RNO-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109415 https://reactome.org/PathwayBrowser/#/R-RNO-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109449 https://reactome.org/PathwayBrowser/#/R-RNO-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109470 https://reactome.org/PathwayBrowser/#/R-RNO-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-109480 https://reactome.org/PathwayBrowser/#/R-RNO-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-109514 https://reactome.org/PathwayBrowser/#/R-RNO-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111742 https://reactome.org/PathwayBrowser/#/R-RNO-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111751 https://reactome.org/PathwayBrowser/#/R-RNO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111804 https://reactome.org/PathwayBrowser/#/R-RNO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111879 https://reactome.org/PathwayBrowser/#/R-RNO-111879 PIP2 hydrolysis IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111955 https://reactome.org/PathwayBrowser/#/R-RNO-111955 cAMP hydrolysis by Cam-PDE 1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-111962 https://reactome.org/PathwayBrowser/#/R-RNO-111962 PDE4A,C,D hydrolyse cAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-112037 https://reactome.org/PathwayBrowser/#/R-RNO-112037 Inactivation of PLC beta IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-113503 https://reactome.org/PathwayBrowser/#/R-RNO-113503 PP2A mediated localization of RB1 protein in chromatin IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1169192 https://reactome.org/PathwayBrowser/#/R-RNO-1169192 PTP1B dephosphorylates GHR IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1183128 https://reactome.org/PathwayBrowser/#/R-RNO-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1237129 https://reactome.org/PathwayBrowser/#/R-RNO-1237129 Acireductone is created IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1247910 https://reactome.org/PathwayBrowser/#/R-RNO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1247935 https://reactome.org/PathwayBrowser/#/R-RNO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-1363274 https://reactome.org/PathwayBrowser/#/R-RNO-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-1363276 https://reactome.org/PathwayBrowser/#/R-RNO-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1369028 https://reactome.org/PathwayBrowser/#/R-RNO-1369028 ABCAs mediate lipid efflux IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1369052 https://reactome.org/PathwayBrowser/#/R-RNO-1369052 ABCAs mediate lipid influx IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1369065 https://reactome.org/PathwayBrowser/#/R-RNO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-139906 https://reactome.org/PathwayBrowser/#/R-RNO-139906 Activation of BAD by calcineurin IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-140359 https://reactome.org/PathwayBrowser/#/R-RNO-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1454916 https://reactome.org/PathwayBrowser/#/R-RNO-1454916 The ABCC family mediates organic anion transport IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1454928 https://reactome.org/PathwayBrowser/#/R-RNO-1454928 ABCG4 may mediate cholesterol efflux IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1467457 https://reactome.org/PathwayBrowser/#/R-RNO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1474146 https://reactome.org/PathwayBrowser/#/R-RNO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482543 https://reactome.org/PathwayBrowser/#/R-RNO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482545 https://reactome.org/PathwayBrowser/#/R-RNO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482571 https://reactome.org/PathwayBrowser/#/R-RNO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482604 https://reactome.org/PathwayBrowser/#/R-RNO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482612 https://reactome.org/PathwayBrowser/#/R-RNO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482629 https://reactome.org/PathwayBrowser/#/R-RNO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482656 https://reactome.org/PathwayBrowser/#/R-RNO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482679 https://reactome.org/PathwayBrowser/#/R-RNO-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482685 https://reactome.org/PathwayBrowser/#/R-RNO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482696 https://reactome.org/PathwayBrowser/#/R-RNO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1482745 https://reactome.org/PathwayBrowser/#/R-RNO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1482759 https://reactome.org/PathwayBrowser/#/R-RNO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482771 https://reactome.org/PathwayBrowser/#/R-RNO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482776 https://reactome.org/PathwayBrowser/#/R-RNO-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482777 https://reactome.org/PathwayBrowser/#/R-RNO-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482811 https://reactome.org/PathwayBrowser/#/R-RNO-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482816 https://reactome.org/PathwayBrowser/#/R-RNO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482825 https://reactome.org/PathwayBrowser/#/R-RNO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482827 https://reactome.org/PathwayBrowser/#/R-RNO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482828 https://reactome.org/PathwayBrowser/#/R-RNO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1482836 https://reactome.org/PathwayBrowser/#/R-RNO-1482836 CL is hydrolyzed to MLCL by Pla2g6 (IM) TAS Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1482847 https://reactome.org/PathwayBrowser/#/R-RNO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482856 https://reactome.org/PathwayBrowser/#/R-RNO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482862 https://reactome.org/PathwayBrowser/#/R-RNO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482868 https://reactome.org/PathwayBrowser/#/R-RNO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482884 https://reactome.org/PathwayBrowser/#/R-RNO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482887 https://reactome.org/PathwayBrowser/#/R-RNO-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482892 https://reactome.org/PathwayBrowser/#/R-RNO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482897 https://reactome.org/PathwayBrowser/#/R-RNO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482900 https://reactome.org/PathwayBrowser/#/R-RNO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482907 https://reactome.org/PathwayBrowser/#/R-RNO-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482920 https://reactome.org/PathwayBrowser/#/R-RNO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1482932 https://reactome.org/PathwayBrowser/#/R-RNO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1483096 https://reactome.org/PathwayBrowser/#/R-RNO-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1483159 https://reactome.org/PathwayBrowser/#/R-RNO-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1483182 https://reactome.org/PathwayBrowser/#/R-RNO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1483203 https://reactome.org/PathwayBrowser/#/R-RNO-1483203 PA is dephosphorylated to DAG by LPIN IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-159425 https://reactome.org/PathwayBrowser/#/R-RNO-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602368 https://reactome.org/PathwayBrowser/#/R-RNO-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602374 https://reactome.org/PathwayBrowser/#/R-RNO-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602377 https://reactome.org/PathwayBrowser/#/R-RNO-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602398 https://reactome.org/PathwayBrowser/#/R-RNO-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602399 https://reactome.org/PathwayBrowser/#/R-RNO-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602417 https://reactome.org/PathwayBrowser/#/R-RNO-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-1602446 https://reactome.org/PathwayBrowser/#/R-RNO-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605591 https://reactome.org/PathwayBrowser/#/R-RNO-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605595 https://reactome.org/PathwayBrowser/#/R-RNO-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605624 https://reactome.org/PathwayBrowser/#/R-RNO-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605632 https://reactome.org/PathwayBrowser/#/R-RNO-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1605723 https://reactome.org/PathwayBrowser/#/R-RNO-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605724 https://reactome.org/PathwayBrowser/#/R-RNO-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605736 https://reactome.org/PathwayBrowser/#/R-RNO-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1605768 https://reactome.org/PathwayBrowser/#/R-RNO-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1606312 https://reactome.org/PathwayBrowser/#/R-RNO-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1606564 https://reactome.org/PathwayBrowser/#/R-RNO-1606564 GALC hydrolyzes GalCer IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1606583 https://reactome.org/PathwayBrowser/#/R-RNO-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1606602 https://reactome.org/PathwayBrowser/#/R-RNO-1606602 ASAH1 hydrolyzes ceramide IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1606789 https://reactome.org/PathwayBrowser/#/R-RNO-1606789 ARSB hydrolyses DS IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-1606839 https://reactome.org/PathwayBrowser/#/R-RNO-1606839 ARSC hydrolyzes steroid sulfates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1614524 https://reactome.org/PathwayBrowser/#/R-RNO-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1614583 https://reactome.org/PathwayBrowser/#/R-RNO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to pyruvate and H2S IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-162425 https://reactome.org/PathwayBrowser/#/R-RNO-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-162729 https://reactome.org/PathwayBrowser/#/R-RNO-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-162857 https://reactome.org/PathwayBrowser/#/R-RNO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1630304 https://reactome.org/PathwayBrowser/#/R-RNO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1630306 https://reactome.org/PathwayBrowser/#/R-RNO-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163398 https://reactome.org/PathwayBrowser/#/R-RNO-163398 phosphorylated HSL + H2O -> HSL + orthophosphate TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163407 https://reactome.org/PathwayBrowser/#/R-RNO-163407 cholesterol ester + H2O -> cholesterol + fatty acid TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163439 https://reactome.org/PathwayBrowser/#/R-RNO-163439 2-acylglycerol + H2O -> glycerol + fatty acid TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163440 https://reactome.org/PathwayBrowser/#/R-RNO-163440 diacylglycerol + H2O -> 2-acylglycerol + fatty acid TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163515 https://reactome.org/PathwayBrowser/#/R-RNO-163515 triacylglycerol + H2O -> diacylglycerol + fatty acid TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-163609 https://reactome.org/PathwayBrowser/#/R-RNO-163609 phosphorylated perilipin + H2O -> perilipin + orthophosphate TAS Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1638032 https://reactome.org/PathwayBrowser/#/R-RNO-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1638053 https://reactome.org/PathwayBrowser/#/R-RNO-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1638821 https://reactome.org/PathwayBrowser/#/R-RNO-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-164832 https://reactome.org/PathwayBrowser/#/R-RNO-164832 ATPase synthesizes ATP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1667005 https://reactome.org/PathwayBrowser/#/R-RNO-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675795 https://reactome.org/PathwayBrowser/#/R-RNO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675824 https://reactome.org/PathwayBrowser/#/R-RNO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675836 https://reactome.org/PathwayBrowser/#/R-RNO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675949 https://reactome.org/PathwayBrowser/#/R-RNO-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675988 https://reactome.org/PathwayBrowser/#/R-RNO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1675994 https://reactome.org/PathwayBrowser/#/R-RNO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676005 https://reactome.org/PathwayBrowser/#/R-RNO-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676020 https://reactome.org/PathwayBrowser/#/R-RNO-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676065 https://reactome.org/PathwayBrowser/#/R-RNO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676105 https://reactome.org/PathwayBrowser/#/R-RNO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676114 https://reactome.org/PathwayBrowser/#/R-RNO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676124 https://reactome.org/PathwayBrowser/#/R-RNO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676141 https://reactome.org/PathwayBrowser/#/R-RNO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676149 https://reactome.org/PathwayBrowser/#/R-RNO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676162 https://reactome.org/PathwayBrowser/#/R-RNO-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676164 https://reactome.org/PathwayBrowser/#/R-RNO-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676174 https://reactome.org/PathwayBrowser/#/R-RNO-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676177 https://reactome.org/PathwayBrowser/#/R-RNO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676203 https://reactome.org/PathwayBrowser/#/R-RNO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1676204 https://reactome.org/PathwayBrowser/#/R-RNO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1678650 https://reactome.org/PathwayBrowser/#/R-RNO-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1678708 https://reactome.org/PathwayBrowser/#/R-RNO-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1678716 https://reactome.org/PathwayBrowser/#/R-RNO-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1678742 https://reactome.org/PathwayBrowser/#/R-RNO-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1678854 https://reactome.org/PathwayBrowser/#/R-RNO-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-170153 https://reactome.org/PathwayBrowser/#/R-RNO-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-170158 https://reactome.org/PathwayBrowser/#/R-RNO-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-170161 https://reactome.org/PathwayBrowser/#/R-RNO-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-173739 https://reactome.org/PathwayBrowser/#/R-RNO-173739 Spontaneous hydrolysis of C3 thioester IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-174110 https://reactome.org/PathwayBrowser/#/R-RNO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-174124 https://reactome.org/PathwayBrowser/#/R-RNO-174124 Dephosphorylation of phospho-Cdh1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-174391 https://reactome.org/PathwayBrowser/#/R-RNO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-174401 https://reactome.org/PathwayBrowser/#/R-RNO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-174439 https://reactome.org/PathwayBrowser/#/R-RNO-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-176606 https://reactome.org/PathwayBrowser/#/R-RNO-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-177923 https://reactome.org/PathwayBrowser/#/R-RNO-177923 Sustained activation of SRC kinase by SHP2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-177924 https://reactome.org/PathwayBrowser/#/R-RNO-177924 Dephosphorylation of Gab1 by SHP2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-177926 https://reactome.org/PathwayBrowser/#/R-RNO-177926 Dephosphorylation of PAG by SHP2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-177935 https://reactome.org/PathwayBrowser/#/R-RNO-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1793182 https://reactome.org/PathwayBrowser/#/R-RNO-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1793186 https://reactome.org/PathwayBrowser/#/R-RNO-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1793207 https://reactome.org/PathwayBrowser/#/R-RNO-1793207 ARSB hydrolyses C4S/C6S chains IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-1793209 https://reactome.org/PathwayBrowser/#/R-RNO-1793209 HYAL1 hydrolyses Chondroitin chains IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-182041 https://reactome.org/PathwayBrowser/#/R-RNO-182041 Endocytosis of clathrin-coated vesicle TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-182061 https://reactome.org/PathwayBrowser/#/R-RNO-182061 Active Plcg1 hydrolyses PIP2 TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855154 https://reactome.org/PathwayBrowser/#/R-RNO-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855159 https://reactome.org/PathwayBrowser/#/R-RNO-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-1855163 https://reactome.org/PathwayBrowser/#/R-RNO-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855165 https://reactome.org/PathwayBrowser/#/R-RNO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855166 https://reactome.org/PathwayBrowser/#/R-RNO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855171 https://reactome.org/PathwayBrowser/#/R-RNO-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855174 https://reactome.org/PathwayBrowser/#/R-RNO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855177 https://reactome.org/PathwayBrowser/#/R-RNO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855180 https://reactome.org/PathwayBrowser/#/R-RNO-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855198 https://reactome.org/PathwayBrowser/#/R-RNO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-1855200 https://reactome.org/PathwayBrowser/#/R-RNO-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855202 https://reactome.org/PathwayBrowser/#/R-RNO-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855205 https://reactome.org/PathwayBrowser/#/R-RNO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855208 https://reactome.org/PathwayBrowser/#/R-RNO-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855210 https://reactome.org/PathwayBrowser/#/R-RNO-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855211 https://reactome.org/PathwayBrowser/#/R-RNO-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855213 https://reactome.org/PathwayBrowser/#/R-RNO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855214 https://reactome.org/PathwayBrowser/#/R-RNO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855218 https://reactome.org/PathwayBrowser/#/R-RNO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855219 https://reactome.org/PathwayBrowser/#/R-RNO-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855221 https://reactome.org/PathwayBrowser/#/R-RNO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855222 https://reactome.org/PathwayBrowser/#/R-RNO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-1855225 https://reactome.org/PathwayBrowser/#/R-RNO-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1855232 https://reactome.org/PathwayBrowser/#/R-RNO-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1861788 https://reactome.org/PathwayBrowser/#/R-RNO-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-1861789 https://reactome.org/PathwayBrowser/#/R-RNO-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-188979 https://reactome.org/PathwayBrowser/#/R-RNO-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-189053 https://reactome.org/PathwayBrowser/#/R-RNO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-189062 https://reactome.org/PathwayBrowser/#/R-RNO-189062 lactose + H2O => D-glucose + D-galactose IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-189069 https://reactome.org/PathwayBrowser/#/R-RNO-189069 sucrose + H2O => glucose + fructose IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-189406 https://reactome.org/PathwayBrowser/#/R-RNO-189406 4 PBGs bind to form HMB IEA Rattus norvegicus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-189488 https://reactome.org/PathwayBrowser/#/R-RNO-189488 UROS transforms HMB to URO3 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-191101 https://reactome.org/PathwayBrowser/#/R-RNO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-191108 https://reactome.org/PathwayBrowser/#/R-RNO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-191114 https://reactome.org/PathwayBrowser/#/R-RNO-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-192331 https://reactome.org/PathwayBrowser/#/R-RNO-192331 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192417 https://reactome.org/PathwayBrowser/#/R-RNO-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192422 https://reactome.org/PathwayBrowser/#/R-RNO-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192425 https://reactome.org/PathwayBrowser/#/R-RNO-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192430 https://reactome.org/PathwayBrowser/#/R-RNO-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192434 https://reactome.org/PathwayBrowser/#/R-RNO-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-192475 https://reactome.org/PathwayBrowser/#/R-RNO-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193362 https://reactome.org/PathwayBrowser/#/R-RNO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-193385 https://reactome.org/PathwayBrowser/#/R-RNO-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-193535 https://reactome.org/PathwayBrowser/#/R-RNO-193535 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193711 https://reactome.org/PathwayBrowser/#/R-RNO-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193727 https://reactome.org/PathwayBrowser/#/R-RNO-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193743 https://reactome.org/PathwayBrowser/#/R-RNO-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193766 https://reactome.org/PathwayBrowser/#/R-RNO-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-196950 https://reactome.org/PathwayBrowser/#/R-RNO-196950 2xTRAP hydrolyzes FMN to RIB IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-197186 https://reactome.org/PathwayBrowser/#/R-RNO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-199425 https://reactome.org/PathwayBrowser/#/R-RNO-199425 PHLPP dephosphorylates S473 in AKT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-199456 https://reactome.org/PathwayBrowser/#/R-RNO-199456 PTEN dephosphorylates PIP3 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-199959 https://reactome.org/PathwayBrowser/#/R-RNO-199959 ERKs are inactivated by protein phosphatase 2A IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-200661 https://reactome.org/PathwayBrowser/#/R-RNO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-200740 https://reactome.org/PathwayBrowser/#/R-RNO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-201035 https://reactome.org/PathwayBrowser/#/R-RNO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-201760 https://reactome.org/PathwayBrowser/#/R-RNO-201760 Ppp3 complex dephosphorylates DARPP-32 on T34 TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-201790 https://reactome.org/PathwayBrowser/#/R-RNO-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-202214 https://reactome.org/PathwayBrowser/#/R-RNO-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022368 https://reactome.org/PathwayBrowser/#/R-RNO-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-202237 https://reactome.org/PathwayBrowser/#/R-RNO-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022378 https://reactome.org/PathwayBrowser/#/R-RNO-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022379 https://reactome.org/PathwayBrowser/#/R-RNO-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022381 https://reactome.org/PathwayBrowser/#/R-RNO-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022383 https://reactome.org/PathwayBrowser/#/R-RNO-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022396 https://reactome.org/PathwayBrowser/#/R-RNO-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022398 https://reactome.org/PathwayBrowser/#/R-RNO-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022399 https://reactome.org/PathwayBrowser/#/R-RNO-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022403 https://reactome.org/PathwayBrowser/#/R-RNO-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022405 https://reactome.org/PathwayBrowser/#/R-RNO-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022411 https://reactome.org/PathwayBrowser/#/R-RNO-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2022412 https://reactome.org/PathwayBrowser/#/R-RNO-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-ALL-2022884 H2O [Golgi lumen] R-RNO-2022887 https://reactome.org/PathwayBrowser/#/R-RNO-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2023971 https://reactome.org/PathwayBrowser/#/R-RNO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2023973 https://reactome.org/PathwayBrowser/#/R-RNO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-202407 https://reactome.org/PathwayBrowser/#/R-RNO-202407 PLC-gamma1 hydrolyses PIP2 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2028294 https://reactome.org/PathwayBrowser/#/R-RNO-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2029468 https://reactome.org/PathwayBrowser/#/R-RNO-2029468 Conversion of PA into DAG by PAP-1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2029471 https://reactome.org/PathwayBrowser/#/R-RNO-2029471 Hydrolysis of PC to PA by PLD IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2029475 https://reactome.org/PathwayBrowser/#/R-RNO-2029475 Production of AA by iPLA2 upon FCGR activation IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 Depalmitoylation of eNOS IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-203797 https://reactome.org/PathwayBrowser/#/R-RNO-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-204169 https://reactome.org/PathwayBrowser/#/R-RNO-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046083 https://reactome.org/PathwayBrowser/#/R-RNO-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046088 https://reactome.org/PathwayBrowser/#/R-RNO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046090 https://reactome.org/PathwayBrowser/#/R-RNO-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046094 https://reactome.org/PathwayBrowser/#/R-RNO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046095 https://reactome.org/PathwayBrowser/#/R-RNO-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2046100 https://reactome.org/PathwayBrowser/#/R-RNO-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2065355 https://reactome.org/PathwayBrowser/#/R-RNO-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2065357 https://reactome.org/PathwayBrowser/#/R-RNO-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-2066778 https://reactome.org/PathwayBrowser/#/R-RNO-2066778 Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-2066779 https://reactome.org/PathwayBrowser/#/R-RNO-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2090037 https://reactome.org/PathwayBrowser/#/R-RNO-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2090038 https://reactome.org/PathwayBrowser/#/R-RNO-2090038 NAGLU hydrolyses heparan chain(2) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2090043 https://reactome.org/PathwayBrowser/#/R-RNO-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2090079 https://reactome.org/PathwayBrowser/#/R-RNO-2090079 GLB1 hydrolyses linker chain(2) IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-209055 https://reactome.org/PathwayBrowser/#/R-RNO-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-209562 https://reactome.org/PathwayBrowser/#/R-RNO-209562 Production of ceramide which can activate JNK and other targets TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15377 R-ALL-351603 H2O [secretory granule lumen] R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2105001 https://reactome.org/PathwayBrowser/#/R-RNO-2105001 HEXA cleaves the terminal GalNAc from DS IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2130725 https://reactome.org/PathwayBrowser/#/R-RNO-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2160874 https://reactome.org/PathwayBrowser/#/R-RNO-2160874 HYAL1 hydrolyses (HA)50 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161791 https://reactome.org/PathwayBrowser/#/R-RNO-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161959 https://reactome.org/PathwayBrowser/#/R-RNO-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161961 https://reactome.org/PathwayBrowser/#/R-RNO-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2161999 https://reactome.org/PathwayBrowser/#/R-RNO-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-2162187 https://reactome.org/PathwayBrowser/#/R-RNO-2162187 COQ6 hydroxylates DHB IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2162225 https://reactome.org/PathwayBrowser/#/R-RNO-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2162226 https://reactome.org/PathwayBrowser/#/R-RNO-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-2162227 https://reactome.org/PathwayBrowser/#/R-RNO-2162227 GUSB tetramer hydrolyses (HA)2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-216723 https://reactome.org/PathwayBrowser/#/R-RNO-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-216757 https://reactome.org/PathwayBrowser/#/R-RNO-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2187401 https://reactome.org/PathwayBrowser/#/R-RNO-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-2309773 https://reactome.org/PathwayBrowser/#/R-RNO-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2393939 https://reactome.org/PathwayBrowser/#/R-RNO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-2393954 https://reactome.org/PathwayBrowser/#/R-RNO-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408502 https://reactome.org/PathwayBrowser/#/R-RNO-2408502 SeCysta is hydrolysed to Sec by PXLP-K211-Cth TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408512 https://reactome.org/PathwayBrowser/#/R-RNO-2408512 AdeSeHCys is hydrolysed to SeHCys by Ahcy TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408521 https://reactome.org/PathwayBrowser/#/R-RNO-2408521 MeSeH is hydrolysed to H2Se by methylselenol demethylase TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408533 https://reactome.org/PathwayBrowser/#/R-RNO-2408533 SeHCys and Ser are dehydrated into SeCysta by Cbs TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408538 https://reactome.org/PathwayBrowser/#/R-RNO-2408538 MeSec is hydrolysed to MeSeH by PXLP-K211-Cth TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408551 https://reactome.org/PathwayBrowser/#/R-RNO-2408551 SeMet is converted to AdoSeMet by MAT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2454118 https://reactome.org/PathwayBrowser/#/R-RNO-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2465924 https://reactome.org/PathwayBrowser/#/R-RNO-2465924 OPN1LW binds 11cRAL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2466085 https://reactome.org/PathwayBrowser/#/R-RNO-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2529015 https://reactome.org/PathwayBrowser/#/R-RNO-2529015 Dephosphorylation of CK2-modified condensin I IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2584246 https://reactome.org/PathwayBrowser/#/R-RNO-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2632521 https://reactome.org/PathwayBrowser/#/R-RNO-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-265783 https://reactome.org/PathwayBrowser/#/R-RNO-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-266012 https://reactome.org/PathwayBrowser/#/R-RNO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-266046 https://reactome.org/PathwayBrowser/#/R-RNO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-266051 https://reactome.org/PathwayBrowser/#/R-RNO-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-266070 https://reactome.org/PathwayBrowser/#/R-RNO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-266072 https://reactome.org/PathwayBrowser/#/R-RNO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-266082 https://reactome.org/PathwayBrowser/#/R-RNO-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2730847 https://reactome.org/PathwayBrowser/#/R-RNO-2730847 Hydrolysis of PIP2 by PLCG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2730849 https://reactome.org/PathwayBrowser/#/R-RNO-2730849 Calcineurin binds and dephosphorylates NFAT IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-2855047 https://reactome.org/PathwayBrowser/#/R-RNO-2855047 Hydrolysis of internal thioester in C4b IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-2995330 https://reactome.org/PathwayBrowser/#/R-RNO-2995330 COX10 transforms heme to heme O IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-2995334 https://reactome.org/PathwayBrowser/#/R-RNO-2995334 COX15 transforms heme O to heme A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-2995388 https://reactome.org/PathwayBrowser/#/R-RNO-2995388 PP2A dephosphorylates BANF1 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-3002811 https://reactome.org/PathwayBrowser/#/R-RNO-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3095901 https://reactome.org/PathwayBrowser/#/R-RNO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-3215295 https://reactome.org/PathwayBrowser/#/R-RNO-3215295 USP7 deubiquitinates MDM2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-3215310 https://reactome.org/PathwayBrowser/#/R-RNO-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-3247569 https://reactome.org/PathwayBrowser/#/R-RNO-3247569 PADI4 deiminates Histones IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-3262512 https://reactome.org/PathwayBrowser/#/R-RNO-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-3322995 https://reactome.org/PathwayBrowser/#/R-RNO-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-3323013 https://reactome.org/PathwayBrowser/#/R-RNO-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3341277 https://reactome.org/PathwayBrowser/#/R-RNO-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-3341296 https://reactome.org/PathwayBrowser/#/R-RNO-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3341343 https://reactome.org/PathwayBrowser/#/R-RNO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-3341397 https://reactome.org/PathwayBrowser/#/R-RNO-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3343700 https://reactome.org/PathwayBrowser/#/R-RNO-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-3371467 https://reactome.org/PathwayBrowser/#/R-RNO-3371467 SIRT1 deacetylates HSF1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-350604 https://reactome.org/PathwayBrowser/#/R-RNO-350604 Agmatine + H2O <=> putrescine + urea IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3640872 https://reactome.org/PathwayBrowser/#/R-RNO-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3697882 https://reactome.org/PathwayBrowser/#/R-RNO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-3697894 https://reactome.org/PathwayBrowser/#/R-RNO-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-377643 https://reactome.org/PathwayBrowser/#/R-RNO-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-3781018 https://reactome.org/PathwayBrowser/#/R-RNO-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-380949 https://reactome.org/PathwayBrowser/#/R-RNO-380949 AMPK is dephosphorylated IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-382553 https://reactome.org/PathwayBrowser/#/R-RNO-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-382560 https://reactome.org/PathwayBrowser/#/R-RNO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-382575 https://reactome.org/PathwayBrowser/#/R-RNO-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-383190 https://reactome.org/PathwayBrowser/#/R-RNO-383190 HCO3- transport through ion channel IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-389986 https://reactome.org/PathwayBrowser/#/R-RNO-389986 trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-390252 https://reactome.org/PathwayBrowser/#/R-RNO-390252 HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-390329 https://reactome.org/PathwayBrowser/#/R-RNO-390329 Dephosphorylation of AKT by PP2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-390393 https://reactome.org/PathwayBrowser/#/R-RNO-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-399998 https://reactome.org/PathwayBrowser/#/R-RNO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4084976 https://reactome.org/PathwayBrowser/#/R-RNO-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4084989 https://reactome.org/PathwayBrowser/#/R-RNO-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4084994 https://reactome.org/PathwayBrowser/#/R-RNO-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-4084999 https://reactome.org/PathwayBrowser/#/R-RNO-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4085021 https://reactome.org/PathwayBrowser/#/R-RNO-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4085029 https://reactome.org/PathwayBrowser/#/R-RNO-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4086392 https://reactome.org/PathwayBrowser/#/R-RNO-4086392 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-4088141 https://reactome.org/PathwayBrowser/#/R-RNO-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4093339 https://reactome.org/PathwayBrowser/#/R-RNO-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-416559 https://reactome.org/PathwayBrowser/#/R-RNO-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-418553 https://reactome.org/PathwayBrowser/#/R-RNO-418553 cAMP degradation by Phosphodiesterases IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428205 https://reactome.org/PathwayBrowser/#/R-RNO-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428231 https://reactome.org/PathwayBrowser/#/R-RNO-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428262 https://reactome.org/PathwayBrowser/#/R-RNO-428262 ACER3 hydrolyzes phytoceramide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428664 https://reactome.org/PathwayBrowser/#/R-RNO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-428690 https://reactome.org/PathwayBrowser/#/R-RNO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-428696 https://reactome.org/PathwayBrowser/#/R-RNO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-429860 https://reactome.org/PathwayBrowser/#/R-RNO-429860 DCP1-DCP2 complex decaps mRNA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-429961 https://reactome.org/PathwayBrowser/#/R-RNO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-430021 https://reactome.org/PathwayBrowser/#/R-RNO-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-430028 https://reactome.org/PathwayBrowser/#/R-RNO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-432010 https://reactome.org/PathwayBrowser/#/R-RNO-432010 Aquaporin-1 passively transports water into cell IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-432010 https://reactome.org/PathwayBrowser/#/R-RNO-432010 Aquaporin-1 passively transports water into cell IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-432054 https://reactome.org/PathwayBrowser/#/R-RNO-432054 Aquaporin-1 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-432054 https://reactome.org/PathwayBrowser/#/R-RNO-432054 Aquaporin-1 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-432065 https://reactome.org/PathwayBrowser/#/R-RNO-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-432065 https://reactome.org/PathwayBrowser/#/R-RNO-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-432067 https://reactome.org/PathwayBrowser/#/R-RNO-432067 Aquaporin-4 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-432067 https://reactome.org/PathwayBrowser/#/R-RNO-432067 Aquaporin-4 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-4419948 https://reactome.org/PathwayBrowser/#/R-RNO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-445714 https://reactome.org/PathwayBrowser/#/R-RNO-445714 Aquaporin-3 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-445714 https://reactome.org/PathwayBrowser/#/R-RNO-445714 Aquaporin-3 passively transports water out of cell IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-449937 https://reactome.org/PathwayBrowser/#/R-RNO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-452036 https://reactome.org/PathwayBrowser/#/R-RNO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4551451 https://reactome.org/PathwayBrowser/#/R-RNO-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-4641236 https://reactome.org/PathwayBrowser/#/R-RNO-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-507868 https://reactome.org/PathwayBrowser/#/R-RNO-507868 Aquaporins passively transport water into cells IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-507868 https://reactome.org/PathwayBrowser/#/R-RNO-507868 Aquaporins passively transport water into cells IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-507870 https://reactome.org/PathwayBrowser/#/R-RNO-507870 Aquaporins passively transport water out of cells IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-507870 https://reactome.org/PathwayBrowser/#/R-RNO-507870 Aquaporins passively transport water out of cells IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5221130 https://reactome.org/PathwayBrowser/#/R-RNO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5223317 https://reactome.org/PathwayBrowser/#/R-RNO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5251955 https://reactome.org/PathwayBrowser/#/R-RNO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5251959 https://reactome.org/PathwayBrowser/#/R-RNO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5251989 https://reactome.org/PathwayBrowser/#/R-RNO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5333610 https://reactome.org/PathwayBrowser/#/R-RNO-5333610 Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec-tRNA(Sec):Eefsec:GTP is hydrolysed to Rpl30:Met-tRNAi:mRNA:Secisbp2:Sec and Eefsec:GDP by Eefsec TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5333611 https://reactome.org/PathwayBrowser/#/R-RNO-5333611 MeSebGalNac is hydrolysed to MeSeH and bGalNac TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5362459 https://reactome.org/PathwayBrowser/#/R-RNO-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-5433072 https://reactome.org/PathwayBrowser/#/R-RNO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5433074 https://reactome.org/PathwayBrowser/#/R-RNO-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-548843 https://reactome.org/PathwayBrowser/#/R-RNO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5603114 https://reactome.org/PathwayBrowser/#/R-RNO-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5607735 https://reactome.org/PathwayBrowser/#/R-RNO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5618093 https://reactome.org/PathwayBrowser/#/R-RNO-5618093 ATP hydrolysis by HSP90 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5623513 https://reactome.org/PathwayBrowser/#/R-RNO-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5628905 https://reactome.org/PathwayBrowser/#/R-RNO-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5631885 https://reactome.org/PathwayBrowser/#/R-RNO-5631885 PRDX1 overoxidizes IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5649705 https://reactome.org/PathwayBrowser/#/R-RNO-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5651828 https://reactome.org/PathwayBrowser/#/R-RNO-5651828 PARG dePARylates PARP1,PARP2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5653770 https://reactome.org/PathwayBrowser/#/R-RNO-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5653786 https://reactome.org/PathwayBrowser/#/R-RNO-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5655945 https://reactome.org/PathwayBrowser/#/R-RNO-5655945 Olah hydrolyzes decanoyl-Fasn dimer to decanoate and Fasn dimer TAS Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-5659861 https://reactome.org/PathwayBrowser/#/R-RNO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Rattus norvegicus 15377 R-ALL-5668574 H2O [melanosome lumen] R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5665809 https://reactome.org/PathwayBrowser/#/R-RNO-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5672957 https://reactome.org/PathwayBrowser/#/R-RNO-5672957 PP2A dephosphorylates KSR1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5672961 https://reactome.org/PathwayBrowser/#/R-RNO-5672961 PP2A dephosphorylates inactive RAFs IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5675373 https://reactome.org/PathwayBrowser/#/R-RNO-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5675376 https://reactome.org/PathwayBrowser/#/R-RNO-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5675431 https://reactome.org/PathwayBrowser/#/R-RNO-5675431 PP2A dephosphorylates RAF1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5675433 https://reactome.org/PathwayBrowser/#/R-RNO-5675433 PP5 dephosphorylates RAF1 S338 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5676637 https://reactome.org/PathwayBrowser/#/R-RNO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5678706 https://reactome.org/PathwayBrowser/#/R-RNO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5678863 https://reactome.org/PathwayBrowser/#/R-RNO-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5679041 https://reactome.org/PathwayBrowser/#/R-RNO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5682285 https://reactome.org/PathwayBrowser/#/R-RNO-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5683405 https://reactome.org/PathwayBrowser/#/R-RNO-5683405 PPP5C dephosphorylates TP53BP1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5683714 https://reactome.org/PathwayBrowser/#/R-RNO-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5683967 https://reactome.org/PathwayBrowser/#/R-RNO-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Rattus norvegicus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-RNO-5684864 https://reactome.org/PathwayBrowser/#/R-RNO-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Rattus norvegicus 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-RNO-5685902 https://reactome.org/PathwayBrowser/#/R-RNO-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5685994 https://reactome.org/PathwayBrowser/#/R-RNO-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5687464 https://reactome.org/PathwayBrowser/#/R-RNO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5687664 https://reactome.org/PathwayBrowser/#/R-RNO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5687758 https://reactome.org/PathwayBrowser/#/R-RNO-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5688797 https://reactome.org/PathwayBrowser/#/R-RNO-5688797 ATXN3 family cleave Ub chains IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5688837 https://reactome.org/PathwayBrowser/#/R-RNO-5688837 ATXN3 deubiquitinates polyUb-PARK2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5689000 https://reactome.org/PathwayBrowser/#/R-RNO-5689000 AADAC deacetylates PHEN IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5689950 https://reactome.org/PathwayBrowser/#/R-RNO-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5689972 https://reactome.org/PathwayBrowser/#/R-RNO-5689972 USP2 deubiquitinates MDM2,MDM4 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5689973 https://reactome.org/PathwayBrowser/#/R-RNO-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690043 https://reactome.org/PathwayBrowser/#/R-RNO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5690066 https://reactome.org/PathwayBrowser/#/R-RNO-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5690080 https://reactome.org/PathwayBrowser/#/R-RNO-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690152 https://reactome.org/PathwayBrowser/#/R-RNO-5690152 USP5 cleaves polyubiquitin IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5690157 https://reactome.org/PathwayBrowser/#/R-RNO-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690159 https://reactome.org/PathwayBrowser/#/R-RNO-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690196 https://reactome.org/PathwayBrowser/#/R-RNO-5690196 USP8 deubiquitinates RNF128 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690319 https://reactome.org/PathwayBrowser/#/R-RNO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-5690517 https://reactome.org/PathwayBrowser/#/R-RNO-5690517 PPT1 hydrolyses palmitoylated proteins IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5690759 https://reactome.org/PathwayBrowser/#/R-RNO-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5690790 https://reactome.org/PathwayBrowser/#/R-RNO-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690808 https://reactome.org/PathwayBrowser/#/R-RNO-5690808 UCHL3, SENP8 cleave NEDD8 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690856 https://reactome.org/PathwayBrowser/#/R-RNO-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5690870 https://reactome.org/PathwayBrowser/#/R-RNO-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5691381 https://reactome.org/PathwayBrowser/#/R-RNO-5691381 MYSM1 deubiquitinates Histone H2A IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5691411 https://reactome.org/PathwayBrowser/#/R-RNO-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5691439 https://reactome.org/PathwayBrowser/#/R-RNO-5691439 BRISC complex deubiquitinates NLRP3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5691507 https://reactome.org/PathwayBrowser/#/R-RNO-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5691512 https://reactome.org/PathwayBrowser/#/R-RNO-5691512 APEH hydrolyses NAc-Ser-protein IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5692462 https://reactome.org/PathwayBrowser/#/R-RNO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5692480 https://reactome.org/PathwayBrowser/#/R-RNO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5692754 https://reactome.org/PathwayBrowser/#/R-RNO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5693153 https://reactome.org/PathwayBrowser/#/R-RNO-5693153 PPM1K dephosphorylates p-BCKDH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5693373 https://reactome.org/PathwayBrowser/#/R-RNO-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5693608 https://reactome.org/PathwayBrowser/#/R-RNO-5693608 Initial resection of double-strand break ends IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-5693724 https://reactome.org/PathwayBrowser/#/R-RNO-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5693742 https://reactome.org/PathwayBrowser/#/R-RNO-5693742 FAAH hydrolyses AEA to AA and ETA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5693783 https://reactome.org/PathwayBrowser/#/R-RNO-5693783 NAALADases hydrolyse NAAG IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-5693807 https://reactome.org/PathwayBrowser/#/R-RNO-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694077 https://reactome.org/PathwayBrowser/#/R-RNO-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-5694109 https://reactome.org/PathwayBrowser/#/R-RNO-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694126 https://reactome.org/PathwayBrowser/#/R-RNO-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5694137 https://reactome.org/PathwayBrowser/#/R-RNO-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694421 https://reactome.org/PathwayBrowser/#/R-RNO-5694421 PP6 dephosphorylates SEC24 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694485 https://reactome.org/PathwayBrowser/#/R-RNO-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5694563 https://reactome.org/PathwayBrowser/#/R-RNO-5694563 ABHD10 hydrolyses MPAG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5694583 https://reactome.org/PathwayBrowser/#/R-RNO-5694583 ABHD4 hydrolyses NAPE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5695964 https://reactome.org/PathwayBrowser/#/R-RNO-5695964 ABHD14B hydrolyses PNPB IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696049 https://reactome.org/PathwayBrowser/#/R-RNO-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5696197 https://reactome.org/PathwayBrowser/#/R-RNO-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696230 https://reactome.org/PathwayBrowser/#/R-RNO-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696365 https://reactome.org/PathwayBrowser/#/R-RNO-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5696408 https://reactome.org/PathwayBrowser/#/R-RNO-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-5696415 https://reactome.org/PathwayBrowser/#/R-RNO-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696465 https://reactome.org/PathwayBrowser/#/R-RNO-5696465 USP45 deubiquitinates ERCC1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696534 https://reactome.org/PathwayBrowser/#/R-RNO-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696564 https://reactome.org/PathwayBrowser/#/R-RNO-5696564 USP25 deubiquitinates DDX58 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696600 https://reactome.org/PathwayBrowser/#/R-RNO-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696605 https://reactome.org/PathwayBrowser/#/R-RNO-5696605 USP12, USP26 deubiquitinate AR IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696627 https://reactome.org/PathwayBrowser/#/R-RNO-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696872 https://reactome.org/PathwayBrowser/#/R-RNO-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696914 https://reactome.org/PathwayBrowser/#/R-RNO-5696914 USP28 deubiquitinates CLSPN and MYC IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696945 https://reactome.org/PathwayBrowser/#/R-RNO-5696945 USP33 deubiquitinates CCP110,ARRB IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696947 https://reactome.org/PathwayBrowser/#/R-RNO-5696947 USP47 deubiquitinates POLB IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696958 https://reactome.org/PathwayBrowser/#/R-RNO-5696958 USP44 deubiquitinates CDC20 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-5696968 https://reactome.org/PathwayBrowser/#/R-RNO-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5696997 https://reactome.org/PathwayBrowser/#/R-RNO-5696997 USP24 deubiquitinates DDB2 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-5697009 https://reactome.org/PathwayBrowser/#/R-RNO-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-622387 https://reactome.org/PathwayBrowser/#/R-RNO-622387 PIP2 hydrolysis TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6781764 https://reactome.org/PathwayBrowser/#/R-RNO-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6781779 https://reactome.org/PathwayBrowser/#/R-RNO-6781779 USP13 deubiquitinates BECN1,USP10 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6781814 https://reactome.org/PathwayBrowser/#/R-RNO-6781814 USP19 deubiquitinates RNF123 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6781897 https://reactome.org/PathwayBrowser/#/R-RNO-6781897 USP11 deubiquitinates NFKBIA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6782069 https://reactome.org/PathwayBrowser/#/R-RNO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6782106 https://reactome.org/PathwayBrowser/#/R-RNO-6782106 USP10 deubiquitinates SNX3, CFTR IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6782628 https://reactome.org/PathwayBrowser/#/R-RNO-6782628 USP8 deubiquitinates STAM2:HGS IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6782820 https://reactome.org/PathwayBrowser/#/R-RNO-6782820 USP17 deubiquitinates SUDS3 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6783177 https://reactome.org/PathwayBrowser/#/R-RNO-6783177 USP21 deubiquitinates GATA3,IL33 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6784402 https://reactome.org/PathwayBrowser/#/R-RNO-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6784959 https://reactome.org/PathwayBrowser/#/R-RNO-6784959 BPHL hydrolyses VACV to ACV IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6786190 https://reactome.org/PathwayBrowser/#/R-RNO-6786190 CMBL hydrolyses OM to OLMS IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6786421 https://reactome.org/PathwayBrowser/#/R-RNO-6786421 CHIA hydrolyses chitin IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6786650 https://reactome.org/PathwayBrowser/#/R-RNO-6786650 DDHD1,2 hydrolyse PA IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6786652 https://reactome.org/PathwayBrowser/#/R-RNO-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6787632 https://reactome.org/PathwayBrowser/#/R-RNO-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6788295 https://reactome.org/PathwayBrowser/#/R-RNO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6788912 https://reactome.org/PathwayBrowser/#/R-RNO-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Rattus norvegicus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6789310 https://reactome.org/PathwayBrowser/#/R-RNO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6792445 https://reactome.org/PathwayBrowser/#/R-RNO-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6792863 https://reactome.org/PathwayBrowser/#/R-RNO-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6797627 https://reactome.org/PathwayBrowser/#/R-RNO-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6797630 https://reactome.org/PathwayBrowser/#/R-RNO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6797653 https://reactome.org/PathwayBrowser/#/R-RNO-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6797913 https://reactome.org/PathwayBrowser/#/R-RNO-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6797955 https://reactome.org/PathwayBrowser/#/R-RNO-6797955 ALDH7A1 oxidises BETALD to BET IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6799545 https://reactome.org/PathwayBrowser/#/R-RNO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-6799581 https://reactome.org/PathwayBrowser/#/R-RNO-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6799604 https://reactome.org/PathwayBrowser/#/R-RNO-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6799695 https://reactome.org/PathwayBrowser/#/R-RNO-6799695 GPX5,6 reduce H2O2 to H2O IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6799977 https://reactome.org/PathwayBrowser/#/R-RNO-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6800198 https://reactome.org/PathwayBrowser/#/R-RNO-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6800200 https://reactome.org/PathwayBrowser/#/R-RNO-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6800299 https://reactome.org/PathwayBrowser/#/R-RNO-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6801462 https://reactome.org/PathwayBrowser/#/R-RNO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6803545 https://reactome.org/PathwayBrowser/#/R-RNO-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-6803753 https://reactome.org/PathwayBrowser/#/R-RNO-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6803789 https://reactome.org/PathwayBrowser/#/R-RNO-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6805650 https://reactome.org/PathwayBrowser/#/R-RNO-6805650 MTA2-NuRD complex deacetylates TP53 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6807008 https://reactome.org/PathwayBrowser/#/R-RNO-6807008 PTPRJ dephosphorylates MET IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6807027 https://reactome.org/PathwayBrowser/#/R-RNO-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6807118 https://reactome.org/PathwayBrowser/#/R-RNO-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6807206 https://reactome.org/PathwayBrowser/#/R-RNO-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-6809263 https://reactome.org/PathwayBrowser/#/R-RNO-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6809320 https://reactome.org/PathwayBrowser/#/R-RNO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6809325 https://reactome.org/PathwayBrowser/#/R-RNO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6809720 https://reactome.org/PathwayBrowser/#/R-RNO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6809777 https://reactome.org/PathwayBrowser/#/R-RNO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6809778 https://reactome.org/PathwayBrowser/#/R-RNO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-6810410 https://reactome.org/PathwayBrowser/#/R-RNO-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6810464 https://reactome.org/PathwayBrowser/#/R-RNO-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-6810472 https://reactome.org/PathwayBrowser/#/R-RNO-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6811504 https://reactome.org/PathwayBrowser/#/R-RNO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6813720 https://reactome.org/PathwayBrowser/#/R-RNO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6813740 https://reactome.org/PathwayBrowser/#/R-RNO-6813740 GDE1 hydrolyzes GroPIns IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-6814254 https://reactome.org/PathwayBrowser/#/R-RNO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-6814797 https://reactome.org/PathwayBrowser/#/R-RNO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-69199 https://reactome.org/PathwayBrowser/#/R-RNO-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70262 https://reactome.org/PathwayBrowser/#/R-RNO-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70479 https://reactome.org/PathwayBrowser/#/R-RNO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70494 https://reactome.org/PathwayBrowser/#/R-RNO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70569 https://reactome.org/PathwayBrowser/#/R-RNO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70609 https://reactome.org/PathwayBrowser/#/R-RNO-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70785 https://reactome.org/PathwayBrowser/#/R-RNO-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70870 https://reactome.org/PathwayBrowser/#/R-RNO-70870 ECHS1 hydrates methacrylyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70903 https://reactome.org/PathwayBrowser/#/R-RNO-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-70906 https://reactome.org/PathwayBrowser/#/R-RNO-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-70982 https://reactome.org/PathwayBrowser/#/R-RNO-70982 FH tetramer hydrates fumarate to L-malate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71146 https://reactome.org/PathwayBrowser/#/R-RNO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71296 https://reactome.org/PathwayBrowser/#/R-RNO-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71660 https://reactome.org/PathwayBrowser/#/R-RNO-71660 Enolase dimers dehydrates 2PG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71676 https://reactome.org/PathwayBrowser/#/R-RNO-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-71732 https://reactome.org/PathwayBrowser/#/R-RNO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-71825 https://reactome.org/PathwayBrowser/#/R-RNO-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73608 https://reactome.org/PathwayBrowser/#/R-RNO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73797 https://reactome.org/PathwayBrowser/#/R-RNO-73797 FAICAR => IMP + H2O IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-73815 https://reactome.org/PathwayBrowser/#/R-RNO-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74059 https://reactome.org/PathwayBrowser/#/R-RNO-74059 PDE6 hydrolyses cGMP to GMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74241 https://reactome.org/PathwayBrowser/#/R-RNO-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74247 https://reactome.org/PathwayBrowser/#/R-RNO-74247 XDH oxidizes hypoxanthine to form xanthine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74248 https://reactome.org/PathwayBrowser/#/R-RNO-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74258 https://reactome.org/PathwayBrowser/#/R-RNO-74258 XDH oxidizes xanthine to form urate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74733 https://reactome.org/PathwayBrowser/#/R-RNO-74733 Insulin receptor de-phosphorylation IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-74948 https://reactome.org/PathwayBrowser/#/R-RNO-74948 PP2A dephosphorylates p-RHO to RHO IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-75899 https://reactome.org/PathwayBrowser/#/R-RNO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-76031 https://reactome.org/PathwayBrowser/#/R-RNO-76031 2 H2O2 => O2 + 2 H2O IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76397 https://reactome.org/PathwayBrowser/#/R-RNO-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-76590 https://reactome.org/PathwayBrowser/#/R-RNO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77256 https://reactome.org/PathwayBrowser/#/R-RNO-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77277 https://reactome.org/PathwayBrowser/#/R-RNO-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77301 https://reactome.org/PathwayBrowser/#/R-RNO-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77314 https://reactome.org/PathwayBrowser/#/R-RNO-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77325 https://reactome.org/PathwayBrowser/#/R-RNO-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77333 https://reactome.org/PathwayBrowser/#/R-RNO-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-77344 https://reactome.org/PathwayBrowser/#/R-RNO-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-77614 https://reactome.org/PathwayBrowser/#/R-RNO-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-77615 https://reactome.org/PathwayBrowser/#/R-RNO-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-83677 https://reactome.org/PathwayBrowser/#/R-RNO-83677 C4 deamination of cytidine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848053 https://reactome.org/PathwayBrowser/#/R-RNO-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848215 https://reactome.org/PathwayBrowser/#/R-RNO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848338 https://reactome.org/PathwayBrowser/#/R-RNO-8848338 PNPLA4 hydrolyzes TAG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848339 https://reactome.org/PathwayBrowser/#/R-RNO-8848339 PNPLA5 hydrolyzes TAG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848355 https://reactome.org/PathwayBrowser/#/R-RNO-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8848484 https://reactome.org/PathwayBrowser/#/R-RNO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8849435 https://reactome.org/PathwayBrowser/#/R-RNO-8849435 PTPN1 dephosphorylates PTK6 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8849857 https://reactome.org/PathwayBrowser/#/R-RNO-8849857 KLK5 cleaves and activates CELA2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8849969 https://reactome.org/PathwayBrowser/#/R-RNO-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8850594 https://reactome.org/PathwayBrowser/#/R-RNO-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8850831 https://reactome.org/PathwayBrowser/#/R-RNO-8850831 KLK5 cleaves and activates KLK8 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-2022884 H2O [Golgi lumen] R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-2022884 H2O [Golgi lumen] R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8852200 https://reactome.org/PathwayBrowser/#/R-RNO-8852200 Inactivation of LCK by PTPN22 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8853379 https://reactome.org/PathwayBrowser/#/R-RNO-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-8853686 https://reactome.org/PathwayBrowser/#/R-RNO-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8854173 https://reactome.org/PathwayBrowser/#/R-RNO-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8854255 https://reactome.org/PathwayBrowser/#/R-RNO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8854329 https://reactome.org/PathwayBrowser/#/R-RNO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8854604 https://reactome.org/PathwayBrowser/#/R-RNO-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8854612 https://reactome.org/PathwayBrowser/#/R-RNO-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8855381 https://reactome.org/PathwayBrowser/#/R-RNO-8855381 PTPN22 dephosphorylates ZAP70 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8855490 https://reactome.org/PathwayBrowser/#/R-RNO-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8855825 https://reactome.org/PathwayBrowser/#/R-RNO-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-8856951 https://reactome.org/PathwayBrowser/#/R-RNO-8856951 PP2A demethylation by PPME1 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-8862184 https://reactome.org/PathwayBrowser/#/R-RNO-8862184 USP48 cleaves polyubiquitin IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8862320 https://reactome.org/PathwayBrowser/#/R-RNO-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8863804 https://reactome.org/PathwayBrowser/#/R-RNO-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8864029 https://reactome.org/PathwayBrowser/#/R-RNO-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8864036 https://reactome.org/PathwayBrowser/#/R-RNO-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8864125 https://reactome.org/PathwayBrowser/#/R-RNO-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-8865667 https://reactome.org/PathwayBrowser/#/R-RNO-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8866405 https://reactome.org/PathwayBrowser/#/R-RNO-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8866542 https://reactome.org/PathwayBrowser/#/R-RNO-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8867047 https://reactome.org/PathwayBrowser/#/R-RNO-8867047 PTPN3 dephosphorylates EPS15 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-8867344 https://reactome.org/PathwayBrowser/#/R-RNO-8867344 OMA1 hydrolyses OPA1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8867658 https://reactome.org/PathwayBrowser/#/R-RNO-8867658 PTPN3 dephosphorylates MAPK12 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8868648 https://reactome.org/PathwayBrowser/#/R-RNO-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8868658 https://reactome.org/PathwayBrowser/#/R-RNO-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8868661 https://reactome.org/PathwayBrowser/#/R-RNO-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8869206 https://reactome.org/PathwayBrowser/#/R-RNO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8869425 https://reactome.org/PathwayBrowser/#/R-RNO-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8869456 https://reactome.org/PathwayBrowser/#/R-RNO-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8869506 https://reactome.org/PathwayBrowser/#/R-RNO-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8874435 https://reactome.org/PathwayBrowser/#/R-RNO-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8875443 https://reactome.org/PathwayBrowser/#/R-RNO-8875443 USP8 deubiquitinates LRIG1 IEA Rattus norvegicus 15377 R-ALL-5668574 H2O [melanosome lumen] R-RNO-8878581 https://reactome.org/PathwayBrowser/#/R-RNO-8878581 TYRP1 oxidises DHICA to IQCA IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-8878654 https://reactome.org/PathwayBrowser/#/R-RNO-8878654 ACP6 hydrolyses MYS-LPA IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8878787 https://reactome.org/PathwayBrowser/#/R-RNO-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8932633 https://reactome.org/PathwayBrowser/#/R-RNO-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8933328 https://reactome.org/PathwayBrowser/#/R-RNO-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Rattus norvegicus 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-893596 https://reactome.org/PathwayBrowser/#/R-RNO-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-8937767 https://reactome.org/PathwayBrowser/#/R-RNO-8937767 PTPN11 dephosphorylates RUNX1 IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8940074 https://reactome.org/PathwayBrowser/#/R-RNO-8940074 NT5E:Zn2+ hydrolyses NMN IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8940388 https://reactome.org/PathwayBrowser/#/R-RNO-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8943279 https://reactome.org/PathwayBrowser/#/R-RNO-8943279 GGT dimers hydrolyse GSH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8952137 https://reactome.org/PathwayBrowser/#/R-RNO-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8952251 https://reactome.org/PathwayBrowser/#/R-RNO-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-8952903 https://reactome.org/PathwayBrowser/#/R-RNO-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8953339 https://reactome.org/PathwayBrowser/#/R-RNO-8953339 DNPH1 hydrolyses dGMP IEA Rattus norvegicus 15377 R-ALL-2022884 H2O [Golgi lumen] R-RNO-8953499 https://reactome.org/PathwayBrowser/#/R-RNO-8953499 IMPAD1 hydrolyses PAP to AMP IEA Rattus norvegicus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-RNO-8954398 https://reactome.org/PathwayBrowser/#/R-RNO-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8955794 https://reactome.org/PathwayBrowser/#/R-RNO-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-8955817 https://reactome.org/PathwayBrowser/#/R-RNO-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-8957389 https://reactome.org/PathwayBrowser/#/R-RNO-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8979996 https://reactome.org/PathwayBrowser/#/R-RNO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-8980228 https://reactome.org/PathwayBrowser/#/R-RNO-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8981637 https://reactome.org/PathwayBrowser/#/R-RNO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-8985594 https://reactome.org/PathwayBrowser/#/R-RNO-8985594 MYO9B inactivates RHOA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9013022 https://reactome.org/PathwayBrowser/#/R-RNO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9013144 https://reactome.org/PathwayBrowser/#/R-RNO-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9013161 https://reactome.org/PathwayBrowser/#/R-RNO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9013437 https://reactome.org/PathwayBrowser/#/R-RNO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9014295 https://reactome.org/PathwayBrowser/#/R-RNO-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9014434 https://reactome.org/PathwayBrowser/#/R-RNO-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9014641 https://reactome.org/PathwayBrowser/#/R-RNO-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9017488 https://reactome.org/PathwayBrowser/#/R-RNO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018745 https://reactome.org/PathwayBrowser/#/R-RNO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018826 https://reactome.org/PathwayBrowser/#/R-RNO-9018826 RHOT2 hydrolyzes GTP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018862 https://reactome.org/PathwayBrowser/#/R-RNO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018868 https://reactome.org/PathwayBrowser/#/R-RNO-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018877 https://reactome.org/PathwayBrowser/#/R-RNO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9018895 https://reactome.org/PathwayBrowser/#/R-RNO-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020252 https://reactome.org/PathwayBrowser/#/R-RNO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020253 https://reactome.org/PathwayBrowser/#/R-RNO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020257 https://reactome.org/PathwayBrowser/#/R-RNO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020258 https://reactome.org/PathwayBrowser/#/R-RNO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020270 https://reactome.org/PathwayBrowser/#/R-RNO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020271 https://reactome.org/PathwayBrowser/#/R-RNO-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9020273 https://reactome.org/PathwayBrowser/#/R-RNO-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9024890 https://reactome.org/PathwayBrowser/#/R-RNO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9024993 https://reactome.org/PathwayBrowser/#/R-RNO-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9026408 https://reactome.org/PathwayBrowser/#/R-RNO-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 15377 R-ALL-141343 H2O [peroxisomal matrix] R-RNO-9033520 https://reactome.org/PathwayBrowser/#/R-RNO-9033520 TYSND1 cleaves TYSND1 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9036727 https://reactome.org/PathwayBrowser/#/R-RNO-9036727 GAA hydrolyzes lysosomal glycogen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-936802 https://reactome.org/PathwayBrowser/#/R-RNO-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-936883 https://reactome.org/PathwayBrowser/#/R-RNO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-936895 https://reactome.org/PathwayBrowser/#/R-RNO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-936897 https://reactome.org/PathwayBrowser/#/R-RNO-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-939763 https://reactome.org/PathwayBrowser/#/R-RNO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-947531 https://reactome.org/PathwayBrowser/#/R-RNO-947531 Molybdenum ion transfer onto molybdopterin IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-947535 https://reactome.org/PathwayBrowser/#/R-RNO-947535 Cyclisation of GTP to precursor Z IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-947591 https://reactome.org/PathwayBrowser/#/R-RNO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-9619441 https://reactome.org/PathwayBrowser/#/R-RNO-9619441 Ppm1e dephosphorylates Camk4 TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9619459 https://reactome.org/PathwayBrowser/#/R-RNO-9619459 Ppm1f dephosphorylates p-T286-CaMKII-alpha TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9619472 https://reactome.org/PathwayBrowser/#/R-RNO-9619472 Ppm1f dephosphorylates Camk1 TAS Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9624893 https://reactome.org/PathwayBrowser/#/R-RNO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9629675 https://reactome.org/PathwayBrowser/#/R-RNO-9629675 PDE3A hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9635739 https://reactome.org/PathwayBrowser/#/R-RNO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9638046 https://reactome.org/PathwayBrowser/#/R-RNO-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9638075 https://reactome.org/PathwayBrowser/#/R-RNO-9638075 HEXB cleaves the terminal GalNAc from DS IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9638076 https://reactome.org/PathwayBrowser/#/R-RNO-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9638078 https://reactome.org/PathwayBrowser/#/R-RNO-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9638120 https://reactome.org/PathwayBrowser/#/R-RNO-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9644869 https://reactome.org/PathwayBrowser/#/R-RNO-9644869 p-S54-PDE4B hydrolyses cAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9647994 https://reactome.org/PathwayBrowser/#/R-RNO-9647994 RAS proteins are depalmitoylated IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-965067 https://reactome.org/PathwayBrowser/#/R-RNO-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-965079 https://reactome.org/PathwayBrowser/#/R-RNO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9653514 https://reactome.org/PathwayBrowser/#/R-RNO-9653514 USP17L2 deubiquitinates RCE1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9656891 https://reactome.org/PathwayBrowser/#/R-RNO-9656891 OPN1SW binds 11cRAL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9656893 https://reactome.org/PathwayBrowser/#/R-RNO-9656893 OPN1MW binds 11cRAL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9658445 https://reactome.org/PathwayBrowser/#/R-RNO-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9659680 https://reactome.org/PathwayBrowser/#/R-RNO-9659680 ABCB1 transports xenobiotics out of the cell IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9661417 https://reactome.org/PathwayBrowser/#/R-RNO-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9667952 https://reactome.org/PathwayBrowser/#/R-RNO-9667952 ANKLE2 is deacetylated by SIRT2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9668419 https://reactome.org/PathwayBrowser/#/R-RNO-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-9673053 https://reactome.org/PathwayBrowser/#/R-RNO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-9673054 https://reactome.org/PathwayBrowser/#/R-RNO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9674127 https://reactome.org/PathwayBrowser/#/R-RNO-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-9686524 https://reactome.org/PathwayBrowser/#/R-RNO-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9693282 https://reactome.org/PathwayBrowser/#/R-RNO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9700200 https://reactome.org/PathwayBrowser/#/R-RNO-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9701507 https://reactome.org/PathwayBrowser/#/R-RNO-9701507 PTPN6 dephosphorylates JAK3 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-9701565 https://reactome.org/PathwayBrowser/#/R-RNO-9701565 HDACs deacetylate p-STAT3 dimers IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9705507 https://reactome.org/PathwayBrowser/#/R-RNO-9705507 PDE3B hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9706399 https://reactome.org/PathwayBrowser/#/R-RNO-9706399 RHOBTB3 hydrolyzes ATP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9708261 https://reactome.org/PathwayBrowser/#/R-RNO-9708261 PDE4A hydrolyses cAMP to AMP IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-9709360 https://reactome.org/PathwayBrowser/#/R-RNO-9709360 H2O2 reduces MetHb IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9727567 https://reactome.org/PathwayBrowser/#/R-RNO-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9749986 https://reactome.org/PathwayBrowser/#/R-RNO-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9750016 https://reactome.org/PathwayBrowser/#/R-RNO-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9750546 https://reactome.org/PathwayBrowser/#/R-RNO-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9750555 https://reactome.org/PathwayBrowser/#/R-RNO-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9750617 https://reactome.org/PathwayBrowser/#/R-RNO-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9750656 https://reactome.org/PathwayBrowser/#/R-RNO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9750942 https://reactome.org/PathwayBrowser/#/R-RNO-9750942 USP14 deubiquitinates NLRC5 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753278 https://reactome.org/PathwayBrowser/#/R-RNO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753280 https://reactome.org/PathwayBrowser/#/R-RNO-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753283 https://reactome.org/PathwayBrowser/#/R-RNO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753284 https://reactome.org/PathwayBrowser/#/R-RNO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753632 https://reactome.org/PathwayBrowser/#/R-RNO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753634 https://reactome.org/PathwayBrowser/#/R-RNO-9753634 GGT dimers hydrolyse APAP-SG IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9753944 https://reactome.org/PathwayBrowser/#/R-RNO-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9754964 https://reactome.org/PathwayBrowser/#/R-RNO-9754964 ADA deamidates RBV IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9755030 https://reactome.org/PathwayBrowser/#/R-RNO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9755078 https://reactome.org/PathwayBrowser/#/R-RNO-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-975593 https://reactome.org/PathwayBrowser/#/R-RNO-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Rattus norvegicus 15377 R-ALL-109276 H2O [extracellular region] R-RNO-975594 https://reactome.org/PathwayBrowser/#/R-RNO-975594 PLB1 hydrolyses RPALM to atROL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9759454 https://reactome.org/PathwayBrowser/#/R-RNO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9759461 https://reactome.org/PathwayBrowser/#/R-RNO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-977324 https://reactome.org/PathwayBrowser/#/R-RNO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9794120 https://reactome.org/PathwayBrowser/#/R-RNO-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9794572 https://reactome.org/PathwayBrowser/#/R-RNO-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-9825772 https://reactome.org/PathwayBrowser/#/R-RNO-9825772 SIRT1 deacetylates HINT1 dimer IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-983144 https://reactome.org/PathwayBrowser/#/R-RNO-983144 Transport of Antigen peptide in to ER IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-983422 https://reactome.org/PathwayBrowser/#/R-RNO-983422 Disassembly of COPII coated vesicle IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9837419 https://reactome.org/PathwayBrowser/#/R-RNO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9838004 https://reactome.org/PathwayBrowser/#/R-RNO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9838081 https://reactome.org/PathwayBrowser/#/R-RNO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9838289 https://reactome.org/PathwayBrowser/#/R-RNO-9838289 CLPXP degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9839059 https://reactome.org/PathwayBrowser/#/R-RNO-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Rattus norvegicus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-RNO-9839072 https://reactome.org/PathwayBrowser/#/R-RNO-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9839105 https://reactome.org/PathwayBrowser/#/R-RNO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Rattus norvegicus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-RNO-9839110 https://reactome.org/PathwayBrowser/#/R-RNO-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9839113 https://reactome.org/PathwayBrowser/#/R-RNO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Rattus norvegicus 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-RNO-9840408 https://reactome.org/PathwayBrowser/#/R-RNO-9840408 OMA1 cleaves DELE1 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9840795 https://reactome.org/PathwayBrowser/#/R-RNO-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9840833 https://reactome.org/PathwayBrowser/#/R-RNO-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9840884 https://reactome.org/PathwayBrowser/#/R-RNO-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9840949 https://reactome.org/PathwayBrowser/#/R-RNO-9840949 ARSA removes sulfate from SM3 IEA Rattus norvegicus 15377 R-ALL-1605715 H2O [lysosomal lumen] R-RNO-9841189 https://reactome.org/PathwayBrowser/#/R-RNO-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9841847 https://reactome.org/PathwayBrowser/#/R-RNO-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9853385 https://reactome.org/PathwayBrowser/#/R-RNO-9853385 PPP1CC dephosphorylates PLK1 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9861626 https://reactome.org/PathwayBrowser/#/R-RNO-9861626 SIRT4 cleaves lipoyl from DLAT IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9861725 https://reactome.org/PathwayBrowser/#/R-RNO-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9865167 https://reactome.org/PathwayBrowser/#/R-RNO-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9865226 https://reactome.org/PathwayBrowser/#/R-RNO-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9912636 https://reactome.org/PathwayBrowser/#/R-RNO-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9912655 https://reactome.org/PathwayBrowser/#/R-RNO-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9912747 https://reactome.org/PathwayBrowser/#/R-RNO-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9912751 https://reactome.org/PathwayBrowser/#/R-RNO-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9915968 https://reactome.org/PathwayBrowser/#/R-RNO-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9915971 https://reactome.org/PathwayBrowser/#/R-RNO-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9915986 https://reactome.org/PathwayBrowser/#/R-RNO-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9915992 https://reactome.org/PathwayBrowser/#/R-RNO-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Rattus norvegicus 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-RNO-9915993 https://reactome.org/PathwayBrowser/#/R-RNO-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9915994 https://reactome.org/PathwayBrowser/#/R-RNO-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9915997 https://reactome.org/PathwayBrowser/#/R-RNO-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-9916401 https://reactome.org/PathwayBrowser/#/R-RNO-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Rattus norvegicus 15377 R-ALL-113521 H2O [mitochondrial matrix] R-RNO-9929439 https://reactome.org/PathwayBrowser/#/R-RNO-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-997309 https://reactome.org/PathwayBrowser/#/R-RNO-997309 Dephosphorylation of STAT1 by SHP2 IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-997311 https://reactome.org/PathwayBrowser/#/R-RNO-997311 Dephosphorylation of TYK2 by PTP1B IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-RNO-997314 https://reactome.org/PathwayBrowser/#/R-RNO-997314 Dephosphorylation of JAK1 by SHP1 IEA Rattus norvegicus 15377 R-ALL-113518 H2O [nucleoplasm] R-RNO-997326 https://reactome.org/PathwayBrowser/#/R-RNO-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Rattus norvegicus 15377 R-ALL-29356 H2O [cytosol] R-SCE-111751 https://reactome.org/PathwayBrowser/#/R-SCE-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-111804 https://reactome.org/PathwayBrowser/#/R-SCE-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-111879 https://reactome.org/PathwayBrowser/#/R-SCE-111879 PIP2 hydrolysis IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-112037 https://reactome.org/PathwayBrowser/#/R-SCE-112037 Inactivation of PLC beta IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1237121 https://reactome.org/PathwayBrowser/#/R-SCE-1237121 Dehydration of methylthio-ribulose-P TAS Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1237129 https://reactome.org/PathwayBrowser/#/R-SCE-1237129 Acireductone is created IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1247910 https://reactome.org/PathwayBrowser/#/R-SCE-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1247935 https://reactome.org/PathwayBrowser/#/R-SCE-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1454916 https://reactome.org/PathwayBrowser/#/R-SCE-1454916 The ABCC family mediates organic anion transport IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1454928 https://reactome.org/PathwayBrowser/#/R-SCE-1454928 ABCG4 may mediate cholesterol efflux IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1474146 https://reactome.org/PathwayBrowser/#/R-SCE-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482543 https://reactome.org/PathwayBrowser/#/R-SCE-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482545 https://reactome.org/PathwayBrowser/#/R-SCE-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482571 https://reactome.org/PathwayBrowser/#/R-SCE-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482604 https://reactome.org/PathwayBrowser/#/R-SCE-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482612 https://reactome.org/PathwayBrowser/#/R-SCE-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482629 https://reactome.org/PathwayBrowser/#/R-SCE-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482656 https://reactome.org/PathwayBrowser/#/R-SCE-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482685 https://reactome.org/PathwayBrowser/#/R-SCE-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482696 https://reactome.org/PathwayBrowser/#/R-SCE-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-1482745 https://reactome.org/PathwayBrowser/#/R-SCE-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-1482759 https://reactome.org/PathwayBrowser/#/R-SCE-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482771 https://reactome.org/PathwayBrowser/#/R-SCE-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482816 https://reactome.org/PathwayBrowser/#/R-SCE-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482825 https://reactome.org/PathwayBrowser/#/R-SCE-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482827 https://reactome.org/PathwayBrowser/#/R-SCE-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482828 https://reactome.org/PathwayBrowser/#/R-SCE-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-1482847 https://reactome.org/PathwayBrowser/#/R-SCE-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482856 https://reactome.org/PathwayBrowser/#/R-SCE-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482862 https://reactome.org/PathwayBrowser/#/R-SCE-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482868 https://reactome.org/PathwayBrowser/#/R-SCE-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482884 https://reactome.org/PathwayBrowser/#/R-SCE-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482892 https://reactome.org/PathwayBrowser/#/R-SCE-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482897 https://reactome.org/PathwayBrowser/#/R-SCE-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482900 https://reactome.org/PathwayBrowser/#/R-SCE-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482920 https://reactome.org/PathwayBrowser/#/R-SCE-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1482932 https://reactome.org/PathwayBrowser/#/R-SCE-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1483182 https://reactome.org/PathwayBrowser/#/R-SCE-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1483203 https://reactome.org/PathwayBrowser/#/R-SCE-1483203 PA is dephosphorylated to DAG by LPIN IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-159425 https://reactome.org/PathwayBrowser/#/R-SCE-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1614524 https://reactome.org/PathwayBrowser/#/R-SCE-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1614583 https://reactome.org/PathwayBrowser/#/R-SCE-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to pyruvate and H2S IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-162857 https://reactome.org/PathwayBrowser/#/R-SCE-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1675795 https://reactome.org/PathwayBrowser/#/R-SCE-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1675836 https://reactome.org/PathwayBrowser/#/R-SCE-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1675949 https://reactome.org/PathwayBrowser/#/R-SCE-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1675988 https://reactome.org/PathwayBrowser/#/R-SCE-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1675994 https://reactome.org/PathwayBrowser/#/R-SCE-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676065 https://reactome.org/PathwayBrowser/#/R-SCE-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676105 https://reactome.org/PathwayBrowser/#/R-SCE-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676114 https://reactome.org/PathwayBrowser/#/R-SCE-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676124 https://reactome.org/PathwayBrowser/#/R-SCE-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676141 https://reactome.org/PathwayBrowser/#/R-SCE-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676149 https://reactome.org/PathwayBrowser/#/R-SCE-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676177 https://reactome.org/PathwayBrowser/#/R-SCE-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676203 https://reactome.org/PathwayBrowser/#/R-SCE-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1676204 https://reactome.org/PathwayBrowser/#/R-SCE-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-174124 https://reactome.org/PathwayBrowser/#/R-SCE-174124 Dephosphorylation of phospho-Cdh1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-174391 https://reactome.org/PathwayBrowser/#/R-SCE-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-174401 https://reactome.org/PathwayBrowser/#/R-SCE-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855154 https://reactome.org/PathwayBrowser/#/R-SCE-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855165 https://reactome.org/PathwayBrowser/#/R-SCE-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855166 https://reactome.org/PathwayBrowser/#/R-SCE-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855174 https://reactome.org/PathwayBrowser/#/R-SCE-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855177 https://reactome.org/PathwayBrowser/#/R-SCE-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855198 https://reactome.org/PathwayBrowser/#/R-SCE-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855205 https://reactome.org/PathwayBrowser/#/R-SCE-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855210 https://reactome.org/PathwayBrowser/#/R-SCE-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855211 https://reactome.org/PathwayBrowser/#/R-SCE-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855214 https://reactome.org/PathwayBrowser/#/R-SCE-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855218 https://reactome.org/PathwayBrowser/#/R-SCE-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-1855221 https://reactome.org/PathwayBrowser/#/R-SCE-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-189406 https://reactome.org/PathwayBrowser/#/R-SCE-189406 4 PBGs bind to form HMB IEA Saccharomyces cerevisiae 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-189488 https://reactome.org/PathwayBrowser/#/R-SCE-189488 UROS transforms HMB to URO3 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-193385 https://reactome.org/PathwayBrowser/#/R-SCE-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-193711 https://reactome.org/PathwayBrowser/#/R-SCE-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-193727 https://reactome.org/PathwayBrowser/#/R-SCE-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-193743 https://reactome.org/PathwayBrowser/#/R-SCE-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-193766 https://reactome.org/PathwayBrowser/#/R-SCE-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-197186 https://reactome.org/PathwayBrowser/#/R-SCE-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-199456 https://reactome.org/PathwayBrowser/#/R-SCE-199456 PTEN dephosphorylates PIP3 IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-199959 https://reactome.org/PathwayBrowser/#/R-SCE-199959 ERKs are inactivated by protein phosphatase 2A IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-200661 https://reactome.org/PathwayBrowser/#/R-SCE-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-200740 https://reactome.org/PathwayBrowser/#/R-SCE-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-201035 https://reactome.org/PathwayBrowser/#/R-SCE-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2023971 https://reactome.org/PathwayBrowser/#/R-SCE-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2023973 https://reactome.org/PathwayBrowser/#/R-SCE-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-202407 https://reactome.org/PathwayBrowser/#/R-SCE-202407 PLC-gamma1 hydrolyses PIP2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2029468 https://reactome.org/PathwayBrowser/#/R-SCE-2029468 Conversion of PA into DAG by PAP-1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2029471 https://reactome.org/PathwayBrowser/#/R-SCE-2029471 Hydrolysis of PC to PA by PLD IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 Depalmitoylation of eNOS IEA Saccharomyces cerevisiae 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SCE-2046088 https://reactome.org/PathwayBrowser/#/R-SCE-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SCE-2046094 https://reactome.org/PathwayBrowser/#/R-SCE-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-2066779 https://reactome.org/PathwayBrowser/#/R-SCE-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-2162187 https://reactome.org/PathwayBrowser/#/R-SCE-2162187 COQ6 hydroxylates DHB IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2393939 https://reactome.org/PathwayBrowser/#/R-SCE-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2408551 https://reactome.org/PathwayBrowser/#/R-SCE-2408551 SeMet is converted to AdoSeMet by MAT IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-2529015 https://reactome.org/PathwayBrowser/#/R-SCE-2529015 Dephosphorylation of CK2-modified condensin I IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-265783 https://reactome.org/PathwayBrowser/#/R-SCE-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-266046 https://reactome.org/PathwayBrowser/#/R-SCE-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-266070 https://reactome.org/PathwayBrowser/#/R-SCE-266070 LTC4 is exported from the cytosol by ABCC1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-266072 https://reactome.org/PathwayBrowser/#/R-SCE-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-266082 https://reactome.org/PathwayBrowser/#/R-SCE-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-2995330 https://reactome.org/PathwayBrowser/#/R-SCE-2995330 COX10 transforms heme to heme O IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-2995334 https://reactome.org/PathwayBrowser/#/R-SCE-2995334 COX15 transforms heme O to heme A IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-3095901 https://reactome.org/PathwayBrowser/#/R-SCE-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-3341343 https://reactome.org/PathwayBrowser/#/R-SCE-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-3697882 https://reactome.org/PathwayBrowser/#/R-SCE-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-3769447 https://reactome.org/PathwayBrowser/#/R-SCE-3769447 HDAC1:2-containing complex deacetylate histones IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-3777129 https://reactome.org/PathwayBrowser/#/R-SCE-3777129 HDAC3 containing complexes deacetylate histone IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-3781011 https://reactome.org/PathwayBrowser/#/R-SCE-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-3781018 https://reactome.org/PathwayBrowser/#/R-SCE-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-3782637 https://reactome.org/PathwayBrowser/#/R-SCE-3782637 HDAC8 deacetylates histones IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-3782655 https://reactome.org/PathwayBrowser/#/R-SCE-3782655 HDAC10 deacetylates histone IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-382560 https://reactome.org/PathwayBrowser/#/R-SCE-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-382575 https://reactome.org/PathwayBrowser/#/R-SCE-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-390329 https://reactome.org/PathwayBrowser/#/R-SCE-390329 Dephosphorylation of AKT by PP2A IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-390393 https://reactome.org/PathwayBrowser/#/R-SCE-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-399998 https://reactome.org/PathwayBrowser/#/R-SCE-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-428262 https://reactome.org/PathwayBrowser/#/R-SCE-428262 ACER3 hydrolyzes phytoceramide IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-428664 https://reactome.org/PathwayBrowser/#/R-SCE-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-428690 https://reactome.org/PathwayBrowser/#/R-SCE-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-428696 https://reactome.org/PathwayBrowser/#/R-SCE-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-429860 https://reactome.org/PathwayBrowser/#/R-SCE-429860 DCP1-DCP2 complex decaps mRNA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-429913 https://reactome.org/PathwayBrowser/#/R-SCE-429913 5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) TAS Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-429961 https://reactome.org/PathwayBrowser/#/R-SCE-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-430021 https://reactome.org/PathwayBrowser/#/R-SCE-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-430028 https://reactome.org/PathwayBrowser/#/R-SCE-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-445714 https://reactome.org/PathwayBrowser/#/R-SCE-445714 Aquaporin-3 passively transports water out of cell IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-445714 https://reactome.org/PathwayBrowser/#/R-SCE-445714 Aquaporin-3 passively transports water out of cell IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-449937 https://reactome.org/PathwayBrowser/#/R-SCE-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-452036 https://reactome.org/PathwayBrowser/#/R-SCE-452036 arginine + H2O => ornithine + urea [ARG2] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-507868 https://reactome.org/PathwayBrowser/#/R-SCE-507868 Aquaporins passively transport water into cells IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-507868 https://reactome.org/PathwayBrowser/#/R-SCE-507868 Aquaporins passively transport water into cells IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-507870 https://reactome.org/PathwayBrowser/#/R-SCE-507870 Aquaporins passively transport water out of cells IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-507870 https://reactome.org/PathwayBrowser/#/R-SCE-507870 Aquaporins passively transport water out of cells IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5221130 https://reactome.org/PathwayBrowser/#/R-SCE-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5251955 https://reactome.org/PathwayBrowser/#/R-SCE-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5251959 https://reactome.org/PathwayBrowser/#/R-SCE-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5251989 https://reactome.org/PathwayBrowser/#/R-SCE-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-5433072 https://reactome.org/PathwayBrowser/#/R-SCE-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-548843 https://reactome.org/PathwayBrowser/#/R-SCE-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5607735 https://reactome.org/PathwayBrowser/#/R-SCE-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5631885 https://reactome.org/PathwayBrowser/#/R-SCE-5631885 PRDX1 overoxidizes IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5653770 https://reactome.org/PathwayBrowser/#/R-SCE-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5676637 https://reactome.org/PathwayBrowser/#/R-SCE-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5679041 https://reactome.org/PathwayBrowser/#/R-SCE-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5683405 https://reactome.org/PathwayBrowser/#/R-SCE-5683405 PPP5C dephosphorylates TP53BP1 IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5689950 https://reactome.org/PathwayBrowser/#/R-SCE-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5690080 https://reactome.org/PathwayBrowser/#/R-SCE-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5690319 https://reactome.org/PathwayBrowser/#/R-SCE-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5690808 https://reactome.org/PathwayBrowser/#/R-SCE-5690808 UCHL3, SENP8 cleave NEDD8 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5692462 https://reactome.org/PathwayBrowser/#/R-SCE-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5692480 https://reactome.org/PathwayBrowser/#/R-SCE-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5692754 https://reactome.org/PathwayBrowser/#/R-SCE-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Saccharomyces cerevisiae 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SCE-5693724 https://reactome.org/PathwayBrowser/#/R-SCE-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5693783 https://reactome.org/PathwayBrowser/#/R-SCE-5693783 NAALADases hydrolyse NAAG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5694421 https://reactome.org/PathwayBrowser/#/R-SCE-5694421 PP6 dephosphorylates SEC24 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5694485 https://reactome.org/PathwayBrowser/#/R-SCE-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5694583 https://reactome.org/PathwayBrowser/#/R-SCE-5694583 ABHD4 hydrolyses NAPE IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5696564 https://reactome.org/PathwayBrowser/#/R-SCE-5696564 USP25 deubiquitinates DDX58 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-5696600 https://reactome.org/PathwayBrowser/#/R-SCE-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-5696914 https://reactome.org/PathwayBrowser/#/R-SCE-5696914 USP28 deubiquitinates CLSPN and MYC IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-6782069 https://reactome.org/PathwayBrowser/#/R-SCE-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6782106 https://reactome.org/PathwayBrowser/#/R-SCE-6782106 USP10 deubiquitinates SNX3, CFTR IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-6782820 https://reactome.org/PathwayBrowser/#/R-SCE-6782820 USP17 deubiquitinates SUDS3 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 15377 R-ALL-5278291 H2O [cytoplasm] R-SCE-6783428 https://reactome.org/PathwayBrowser/#/R-SCE-6783428 TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 at nucleotide 37 of tRNA(Phe) TAS Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-6786421 https://reactome.org/PathwayBrowser/#/R-SCE-6786421 CHIA hydrolyses chitin IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6786650 https://reactome.org/PathwayBrowser/#/R-SCE-6786650 DDHD1,2 hydrolyse PA IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-6786652 https://reactome.org/PathwayBrowser/#/R-SCE-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6788295 https://reactome.org/PathwayBrowser/#/R-SCE-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-6789310 https://reactome.org/PathwayBrowser/#/R-SCE-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Saccharomyces cerevisiae 15377 R-ALL-5278291 H2O [cytoplasm] R-SCE-6790128 https://reactome.org/PathwayBrowser/#/R-SCE-6790128 TAD1 deaminates adenosine-37 in tRNA(Ala) yielding inosine-37 TAS Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-6797630 https://reactome.org/PathwayBrowser/#/R-SCE-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6799545 https://reactome.org/PathwayBrowser/#/R-SCE-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-6801462 https://reactome.org/PathwayBrowser/#/R-SCE-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-6807118 https://reactome.org/PathwayBrowser/#/R-SCE-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6809320 https://reactome.org/PathwayBrowser/#/R-SCE-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6809325 https://reactome.org/PathwayBrowser/#/R-SCE-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6809720 https://reactome.org/PathwayBrowser/#/R-SCE-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6809777 https://reactome.org/PathwayBrowser/#/R-SCE-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6809778 https://reactome.org/PathwayBrowser/#/R-SCE-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6811504 https://reactome.org/PathwayBrowser/#/R-SCE-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-6814254 https://reactome.org/PathwayBrowser/#/R-SCE-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-6814797 https://reactome.org/PathwayBrowser/#/R-SCE-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-70262 https://reactome.org/PathwayBrowser/#/R-SCE-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-70479 https://reactome.org/PathwayBrowser/#/R-SCE-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-70494 https://reactome.org/PathwayBrowser/#/R-SCE-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-70569 https://reactome.org/PathwayBrowser/#/R-SCE-70569 arginine + H2O => ornithine + urea [ARG1] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-70982 https://reactome.org/PathwayBrowser/#/R-SCE-70982 FH tetramer hydrates fumarate to L-malate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71146 https://reactome.org/PathwayBrowser/#/R-SCE-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71296 https://reactome.org/PathwayBrowser/#/R-SCE-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71660 https://reactome.org/PathwayBrowser/#/R-SCE-71660 Enolase dimers dehydrates 2PG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-71732 https://reactome.org/PathwayBrowser/#/R-SCE-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73608 https://reactome.org/PathwayBrowser/#/R-SCE-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73797 https://reactome.org/PathwayBrowser/#/R-SCE-73797 FAICAR => IMP + H2O IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-75899 https://reactome.org/PathwayBrowser/#/R-SCE-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Saccharomyces cerevisiae 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SCE-76031 https://reactome.org/PathwayBrowser/#/R-SCE-76031 2 H2O2 => O2 + 2 H2O IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-76590 https://reactome.org/PathwayBrowser/#/R-SCE-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8848215 https://reactome.org/PathwayBrowser/#/R-SCE-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8848484 https://reactome.org/PathwayBrowser/#/R-SCE-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Saccharomyces cerevisiae 15377 R-ALL-2022884 H2O [Golgi lumen] R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-ALL-2022884 H2O [Golgi lumen] R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8854255 https://reactome.org/PathwayBrowser/#/R-SCE-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8854329 https://reactome.org/PathwayBrowser/#/R-SCE-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Saccharomyces cerevisiae 15377 R-ALL-113518 H2O [nucleoplasm] R-SCE-8856951 https://reactome.org/PathwayBrowser/#/R-SCE-8856951 PP2A demethylation by PPME1 IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-8867344 https://reactome.org/PathwayBrowser/#/R-SCE-8867344 OMA1 hydrolyses OPA1 IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-893596 https://reactome.org/PathwayBrowser/#/R-SCE-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8940388 https://reactome.org/PathwayBrowser/#/R-SCE-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8943279 https://reactome.org/PathwayBrowser/#/R-SCE-8943279 GGT dimers hydrolyse GSH IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8952137 https://reactome.org/PathwayBrowser/#/R-SCE-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8952251 https://reactome.org/PathwayBrowser/#/R-SCE-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-8955817 https://reactome.org/PathwayBrowser/#/R-SCE-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-8979996 https://reactome.org/PathwayBrowser/#/R-SCE-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-8981637 https://reactome.org/PathwayBrowser/#/R-SCE-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9013022 https://reactome.org/PathwayBrowser/#/R-SCE-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9013111 https://reactome.org/PathwayBrowser/#/R-SCE-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9013161 https://reactome.org/PathwayBrowser/#/R-SCE-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9013437 https://reactome.org/PathwayBrowser/#/R-SCE-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9014641 https://reactome.org/PathwayBrowser/#/R-SCE-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9017488 https://reactome.org/PathwayBrowser/#/R-SCE-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9018745 https://reactome.org/PathwayBrowser/#/R-SCE-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9018814 https://reactome.org/PathwayBrowser/#/R-SCE-9018814 RHOT1 hydrolyzes GTP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9018826 https://reactome.org/PathwayBrowser/#/R-SCE-9018826 RHOT2 hydrolyzes GTP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9018862 https://reactome.org/PathwayBrowser/#/R-SCE-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9018877 https://reactome.org/PathwayBrowser/#/R-SCE-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9020252 https://reactome.org/PathwayBrowser/#/R-SCE-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9020253 https://reactome.org/PathwayBrowser/#/R-SCE-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9020257 https://reactome.org/PathwayBrowser/#/R-SCE-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9020258 https://reactome.org/PathwayBrowser/#/R-SCE-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9020270 https://reactome.org/PathwayBrowser/#/R-SCE-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9024890 https://reactome.org/PathwayBrowser/#/R-SCE-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-936883 https://reactome.org/PathwayBrowser/#/R-SCE-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-936895 https://reactome.org/PathwayBrowser/#/R-SCE-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-939763 https://reactome.org/PathwayBrowser/#/R-SCE-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-947591 https://reactome.org/PathwayBrowser/#/R-SCE-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9624893 https://reactome.org/PathwayBrowser/#/R-SCE-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9635739 https://reactome.org/PathwayBrowser/#/R-SCE-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-965079 https://reactome.org/PathwayBrowser/#/R-SCE-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9653514 https://reactome.org/PathwayBrowser/#/R-SCE-9653514 USP17L2 deubiquitinates RCE1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9661417 https://reactome.org/PathwayBrowser/#/R-SCE-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-9673053 https://reactome.org/PathwayBrowser/#/R-SCE-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Saccharomyces cerevisiae 15377 R-ALL-109276 H2O [extracellular region] R-SCE-9673054 https://reactome.org/PathwayBrowser/#/R-SCE-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9693282 https://reactome.org/PathwayBrowser/#/R-SCE-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9750656 https://reactome.org/PathwayBrowser/#/R-SCE-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9753278 https://reactome.org/PathwayBrowser/#/R-SCE-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9753283 https://reactome.org/PathwayBrowser/#/R-SCE-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9753284 https://reactome.org/PathwayBrowser/#/R-SCE-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9753632 https://reactome.org/PathwayBrowser/#/R-SCE-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9753634 https://reactome.org/PathwayBrowser/#/R-SCE-9753634 GGT dimers hydrolyse APAP-SG IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9755030 https://reactome.org/PathwayBrowser/#/R-SCE-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-977324 https://reactome.org/PathwayBrowser/#/R-SCE-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9794120 https://reactome.org/PathwayBrowser/#/R-SCE-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9794572 https://reactome.org/PathwayBrowser/#/R-SCE-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9837419 https://reactome.org/PathwayBrowser/#/R-SCE-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-9838004 https://reactome.org/PathwayBrowser/#/R-SCE-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-9838081 https://reactome.org/PathwayBrowser/#/R-SCE-9838081 LONP1 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-9839105 https://reactome.org/PathwayBrowser/#/R-SCE-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Saccharomyces cerevisiae 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SCE-9839113 https://reactome.org/PathwayBrowser/#/R-SCE-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Saccharomyces cerevisiae 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SCE-9839836 https://reactome.org/PathwayBrowser/#/R-SCE-9839836 YME1 degrades TIM10 TAS Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9853385 https://reactome.org/PathwayBrowser/#/R-SCE-9853385 PPP1CC dephosphorylates PLK1 IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9912636 https://reactome.org/PathwayBrowser/#/R-SCE-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9912655 https://reactome.org/PathwayBrowser/#/R-SCE-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9912747 https://reactome.org/PathwayBrowser/#/R-SCE-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SCE-9912751 https://reactome.org/PathwayBrowser/#/R-SCE-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Saccharomyces cerevisiae 15377 R-ALL-29356 H2O [cytosol] R-SPO-111751 https://reactome.org/PathwayBrowser/#/R-SPO-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-111804 https://reactome.org/PathwayBrowser/#/R-SPO-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-111879 https://reactome.org/PathwayBrowser/#/R-SPO-111879 PIP2 hydrolysis IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-112037 https://reactome.org/PathwayBrowser/#/R-SPO-112037 Inactivation of PLC beta IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1237129 https://reactome.org/PathwayBrowser/#/R-SPO-1237129 Acireductone is created IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1247910 https://reactome.org/PathwayBrowser/#/R-SPO-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1247935 https://reactome.org/PathwayBrowser/#/R-SPO-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1369065 https://reactome.org/PathwayBrowser/#/R-SPO-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1454916 https://reactome.org/PathwayBrowser/#/R-SPO-1454916 The ABCC family mediates organic anion transport IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1467457 https://reactome.org/PathwayBrowser/#/R-SPO-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1474146 https://reactome.org/PathwayBrowser/#/R-SPO-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482543 https://reactome.org/PathwayBrowser/#/R-SPO-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482545 https://reactome.org/PathwayBrowser/#/R-SPO-1482545 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482571 https://reactome.org/PathwayBrowser/#/R-SPO-1482571 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482604 https://reactome.org/PathwayBrowser/#/R-SPO-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482612 https://reactome.org/PathwayBrowser/#/R-SPO-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482629 https://reactome.org/PathwayBrowser/#/R-SPO-1482629 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482656 https://reactome.org/PathwayBrowser/#/R-SPO-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482685 https://reactome.org/PathwayBrowser/#/R-SPO-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482696 https://reactome.org/PathwayBrowser/#/R-SPO-1482696 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-1482745 https://reactome.org/PathwayBrowser/#/R-SPO-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-1482759 https://reactome.org/PathwayBrowser/#/R-SPO-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482771 https://reactome.org/PathwayBrowser/#/R-SPO-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482816 https://reactome.org/PathwayBrowser/#/R-SPO-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482825 https://reactome.org/PathwayBrowser/#/R-SPO-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482827 https://reactome.org/PathwayBrowser/#/R-SPO-1482827 PC is hydrolyzed to 2-acyl LPC by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482828 https://reactome.org/PathwayBrowser/#/R-SPO-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-1482847 https://reactome.org/PathwayBrowser/#/R-SPO-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482856 https://reactome.org/PathwayBrowser/#/R-SPO-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482862 https://reactome.org/PathwayBrowser/#/R-SPO-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482868 https://reactome.org/PathwayBrowser/#/R-SPO-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482884 https://reactome.org/PathwayBrowser/#/R-SPO-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482892 https://reactome.org/PathwayBrowser/#/R-SPO-1482892 PE is hydrolyzed to 2-acyl LPE by PLA2G4C IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482897 https://reactome.org/PathwayBrowser/#/R-SPO-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482900 https://reactome.org/PathwayBrowser/#/R-SPO-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482920 https://reactome.org/PathwayBrowser/#/R-SPO-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1482932 https://reactome.org/PathwayBrowser/#/R-SPO-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1483182 https://reactome.org/PathwayBrowser/#/R-SPO-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1483203 https://reactome.org/PathwayBrowser/#/R-SPO-1483203 PA is dephosphorylated to DAG by LPIN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SPO-1606839 https://reactome.org/PathwayBrowser/#/R-SPO-1606839 ARSC hydrolyzes steroid sulfates IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1614583 https://reactome.org/PathwayBrowser/#/R-SPO-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to pyruvate and H2S IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-162857 https://reactome.org/PathwayBrowser/#/R-SPO-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Schizosaccharomyces pombe 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SPO-1630304 https://reactome.org/PathwayBrowser/#/R-SPO-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1675795 https://reactome.org/PathwayBrowser/#/R-SPO-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1675824 https://reactome.org/PathwayBrowser/#/R-SPO-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1675836 https://reactome.org/PathwayBrowser/#/R-SPO-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1675988 https://reactome.org/PathwayBrowser/#/R-SPO-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1675994 https://reactome.org/PathwayBrowser/#/R-SPO-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676065 https://reactome.org/PathwayBrowser/#/R-SPO-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676105 https://reactome.org/PathwayBrowser/#/R-SPO-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676114 https://reactome.org/PathwayBrowser/#/R-SPO-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676124 https://reactome.org/PathwayBrowser/#/R-SPO-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676141 https://reactome.org/PathwayBrowser/#/R-SPO-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676149 https://reactome.org/PathwayBrowser/#/R-SPO-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676177 https://reactome.org/PathwayBrowser/#/R-SPO-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676203 https://reactome.org/PathwayBrowser/#/R-SPO-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1676204 https://reactome.org/PathwayBrowser/#/R-SPO-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-174110 https://reactome.org/PathwayBrowser/#/R-SPO-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-174124 https://reactome.org/PathwayBrowser/#/R-SPO-174124 Dephosphorylation of phospho-Cdh1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-174391 https://reactome.org/PathwayBrowser/#/R-SPO-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-174401 https://reactome.org/PathwayBrowser/#/R-SPO-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855165 https://reactome.org/PathwayBrowser/#/R-SPO-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855166 https://reactome.org/PathwayBrowser/#/R-SPO-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855174 https://reactome.org/PathwayBrowser/#/R-SPO-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855177 https://reactome.org/PathwayBrowser/#/R-SPO-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855198 https://reactome.org/PathwayBrowser/#/R-SPO-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855205 https://reactome.org/PathwayBrowser/#/R-SPO-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855213 https://reactome.org/PathwayBrowser/#/R-SPO-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855214 https://reactome.org/PathwayBrowser/#/R-SPO-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855218 https://reactome.org/PathwayBrowser/#/R-SPO-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855221 https://reactome.org/PathwayBrowser/#/R-SPO-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-1855222 https://reactome.org/PathwayBrowser/#/R-SPO-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-189053 https://reactome.org/PathwayBrowser/#/R-SPO-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-189069 https://reactome.org/PathwayBrowser/#/R-SPO-189069 sucrose + H2O => glucose + fructose IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-189102 https://reactome.org/PathwayBrowser/#/R-SPO-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-189406 https://reactome.org/PathwayBrowser/#/R-SPO-189406 4 PBGs bind to form HMB IEA Schizosaccharomyces pombe 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-189488 https://reactome.org/PathwayBrowser/#/R-SPO-189488 UROS transforms HMB to URO3 IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-191101 https://reactome.org/PathwayBrowser/#/R-SPO-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-191108 https://reactome.org/PathwayBrowser/#/R-SPO-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-191116 https://reactome.org/PathwayBrowser/#/R-SPO-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-193362 https://reactome.org/PathwayBrowser/#/R-SPO-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-197186 https://reactome.org/PathwayBrowser/#/R-SPO-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-199456 https://reactome.org/PathwayBrowser/#/R-SPO-199456 PTEN dephosphorylates PIP3 IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-199959 https://reactome.org/PathwayBrowser/#/R-SPO-199959 ERKs are inactivated by protein phosphatase 2A IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-200661 https://reactome.org/PathwayBrowser/#/R-SPO-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-200740 https://reactome.org/PathwayBrowser/#/R-SPO-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-201035 https://reactome.org/PathwayBrowser/#/R-SPO-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2023971 https://reactome.org/PathwayBrowser/#/R-SPO-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2023973 https://reactome.org/PathwayBrowser/#/R-SPO-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-202407 https://reactome.org/PathwayBrowser/#/R-SPO-202407 PLC-gamma1 hydrolyses PIP2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2029468 https://reactome.org/PathwayBrowser/#/R-SPO-2029468 Conversion of PA into DAG by PAP-1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2029471 https://reactome.org/PathwayBrowser/#/R-SPO-2029471 Hydrolysis of PC to PA by PLD IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 Depalmitoylation of eNOS IEA Schizosaccharomyces pombe 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SPO-2046088 https://reactome.org/PathwayBrowser/#/R-SPO-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SPO-2046094 https://reactome.org/PathwayBrowser/#/R-SPO-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-2162187 https://reactome.org/PathwayBrowser/#/R-SPO-2162187 COQ6 hydroxylates DHB IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2393939 https://reactome.org/PathwayBrowser/#/R-SPO-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2408551 https://reactome.org/PathwayBrowser/#/R-SPO-2408551 SeMet is converted to AdoSeMet by MAT IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-2529015 https://reactome.org/PathwayBrowser/#/R-SPO-2529015 Dephosphorylation of CK2-modified condensin I IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-266012 https://reactome.org/PathwayBrowser/#/R-SPO-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-266046 https://reactome.org/PathwayBrowser/#/R-SPO-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-266070 https://reactome.org/PathwayBrowser/#/R-SPO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-266072 https://reactome.org/PathwayBrowser/#/R-SPO-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-2995330 https://reactome.org/PathwayBrowser/#/R-SPO-2995330 COX10 transforms heme to heme O IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-2995334 https://reactome.org/PathwayBrowser/#/R-SPO-2995334 COX15 transforms heme O to heme A IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-3095901 https://reactome.org/PathwayBrowser/#/R-SPO-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-3341343 https://reactome.org/PathwayBrowser/#/R-SPO-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-3697882 https://reactome.org/PathwayBrowser/#/R-SPO-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-3769447 https://reactome.org/PathwayBrowser/#/R-SPO-3769447 HDAC1:2-containing complex deacetylate histones IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-3782655 https://reactome.org/PathwayBrowser/#/R-SPO-3782655 HDAC10 deacetylates histone IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-382560 https://reactome.org/PathwayBrowser/#/R-SPO-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Schizosaccharomyces pombe 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SPO-389821 https://reactome.org/PathwayBrowser/#/R-SPO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-390329 https://reactome.org/PathwayBrowser/#/R-SPO-390329 Dephosphorylation of AKT by PP2A IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-399998 https://reactome.org/PathwayBrowser/#/R-SPO-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-428664 https://reactome.org/PathwayBrowser/#/R-SPO-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-428690 https://reactome.org/PathwayBrowser/#/R-SPO-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-428696 https://reactome.org/PathwayBrowser/#/R-SPO-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-429961 https://reactome.org/PathwayBrowser/#/R-SPO-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-430028 https://reactome.org/PathwayBrowser/#/R-SPO-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-4419948 https://reactome.org/PathwayBrowser/#/R-SPO-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-445714 https://reactome.org/PathwayBrowser/#/R-SPO-445714 Aquaporin-3 passively transports water out of cell IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-445714 https://reactome.org/PathwayBrowser/#/R-SPO-445714 Aquaporin-3 passively transports water out of cell IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-449937 https://reactome.org/PathwayBrowser/#/R-SPO-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-452036 https://reactome.org/PathwayBrowser/#/R-SPO-452036 arginine + H2O => ornithine + urea [ARG2] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-507868 https://reactome.org/PathwayBrowser/#/R-SPO-507868 Aquaporins passively transport water into cells IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-507868 https://reactome.org/PathwayBrowser/#/R-SPO-507868 Aquaporins passively transport water into cells IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-507870 https://reactome.org/PathwayBrowser/#/R-SPO-507870 Aquaporins passively transport water out of cells IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-507870 https://reactome.org/PathwayBrowser/#/R-SPO-507870 Aquaporins passively transport water out of cells IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5221130 https://reactome.org/PathwayBrowser/#/R-SPO-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5223317 https://reactome.org/PathwayBrowser/#/R-SPO-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5251955 https://reactome.org/PathwayBrowser/#/R-SPO-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5251959 https://reactome.org/PathwayBrowser/#/R-SPO-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5251989 https://reactome.org/PathwayBrowser/#/R-SPO-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-5433072 https://reactome.org/PathwayBrowser/#/R-SPO-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-548843 https://reactome.org/PathwayBrowser/#/R-SPO-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5607735 https://reactome.org/PathwayBrowser/#/R-SPO-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5631885 https://reactome.org/PathwayBrowser/#/R-SPO-5631885 PRDX1 overoxidizes IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5653770 https://reactome.org/PathwayBrowser/#/R-SPO-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-5659861 https://reactome.org/PathwayBrowser/#/R-SPO-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5676637 https://reactome.org/PathwayBrowser/#/R-SPO-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5678706 https://reactome.org/PathwayBrowser/#/R-SPO-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5679041 https://reactome.org/PathwayBrowser/#/R-SPO-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5683405 https://reactome.org/PathwayBrowser/#/R-SPO-5683405 PPP5C dephosphorylates TP53BP1 IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5687464 https://reactome.org/PathwayBrowser/#/R-SPO-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5687664 https://reactome.org/PathwayBrowser/#/R-SPO-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5689000 https://reactome.org/PathwayBrowser/#/R-SPO-5689000 AADAC deacetylates PHEN IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5689950 https://reactome.org/PathwayBrowser/#/R-SPO-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5690043 https://reactome.org/PathwayBrowser/#/R-SPO-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5690080 https://reactome.org/PathwayBrowser/#/R-SPO-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5690152 https://reactome.org/PathwayBrowser/#/R-SPO-5690152 USP5 cleaves polyubiquitin IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5690319 https://reactome.org/PathwayBrowser/#/R-SPO-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5690808 https://reactome.org/PathwayBrowser/#/R-SPO-5690808 UCHL3, SENP8 cleave NEDD8 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5692462 https://reactome.org/PathwayBrowser/#/R-SPO-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5692480 https://reactome.org/PathwayBrowser/#/R-SPO-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5692754 https://reactome.org/PathwayBrowser/#/R-SPO-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5693783 https://reactome.org/PathwayBrowser/#/R-SPO-5693783 NAALADases hydrolyse NAAG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5694583 https://reactome.org/PathwayBrowser/#/R-SPO-5694583 ABHD4 hydrolyses NAPE IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5696600 https://reactome.org/PathwayBrowser/#/R-SPO-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5696605 https://reactome.org/PathwayBrowser/#/R-SPO-5696605 USP12, USP26 deubiquitinate AR IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-5696872 https://reactome.org/PathwayBrowser/#/R-SPO-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5696914 https://reactome.org/PathwayBrowser/#/R-SPO-5696914 USP28 deubiquitinates CLSPN and MYC IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-5697009 https://reactome.org/PathwayBrowser/#/R-SPO-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6781779 https://reactome.org/PathwayBrowser/#/R-SPO-6781779 USP13 deubiquitinates BECN1,USP10 IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-6782069 https://reactome.org/PathwayBrowser/#/R-SPO-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6782106 https://reactome.org/PathwayBrowser/#/R-SPO-6782106 USP10 deubiquitinates SNX3, CFTR IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-6782820 https://reactome.org/PathwayBrowser/#/R-SPO-6782820 USP17 deubiquitinates SUDS3 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6786650 https://reactome.org/PathwayBrowser/#/R-SPO-6786650 DDHD1,2 hydrolyse PA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6788295 https://reactome.org/PathwayBrowser/#/R-SPO-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-6789310 https://reactome.org/PathwayBrowser/#/R-SPO-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-6797630 https://reactome.org/PathwayBrowser/#/R-SPO-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6799545 https://reactome.org/PathwayBrowser/#/R-SPO-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-6801462 https://reactome.org/PathwayBrowser/#/R-SPO-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-6807118 https://reactome.org/PathwayBrowser/#/R-SPO-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6807206 https://reactome.org/PathwayBrowser/#/R-SPO-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Schizosaccharomyces pombe 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6809320 https://reactome.org/PathwayBrowser/#/R-SPO-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6809325 https://reactome.org/PathwayBrowser/#/R-SPO-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6809720 https://reactome.org/PathwayBrowser/#/R-SPO-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6809777 https://reactome.org/PathwayBrowser/#/R-SPO-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6809778 https://reactome.org/PathwayBrowser/#/R-SPO-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Schizosaccharomyces pombe 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SPO-6810076 https://reactome.org/PathwayBrowser/#/R-SPO-6810076 DDO oxidizes D-Asp to OA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6811504 https://reactome.org/PathwayBrowser/#/R-SPO-6811504 AKT1 dephosphorylation by PP2A-B56-beta,gamma IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6813720 https://reactome.org/PathwayBrowser/#/R-SPO-6813720 NCEH1 hydrolyzes cholesterol esters IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-6814254 https://reactome.org/PathwayBrowser/#/R-SPO-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-6814797 https://reactome.org/PathwayBrowser/#/R-SPO-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-70262 https://reactome.org/PathwayBrowser/#/R-SPO-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-70479 https://reactome.org/PathwayBrowser/#/R-SPO-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-70494 https://reactome.org/PathwayBrowser/#/R-SPO-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-70569 https://reactome.org/PathwayBrowser/#/R-SPO-70569 arginine + H2O => ornithine + urea [ARG1] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-70982 https://reactome.org/PathwayBrowser/#/R-SPO-70982 FH tetramer hydrates fumarate to L-malate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-71146 https://reactome.org/PathwayBrowser/#/R-SPO-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-71296 https://reactome.org/PathwayBrowser/#/R-SPO-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-71660 https://reactome.org/PathwayBrowser/#/R-SPO-71660 Enolase dimers dehydrates 2PG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-71732 https://reactome.org/PathwayBrowser/#/R-SPO-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73608 https://reactome.org/PathwayBrowser/#/R-SPO-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73797 https://reactome.org/PathwayBrowser/#/R-SPO-73797 FAICAR => IMP + H2O IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-75899 https://reactome.org/PathwayBrowser/#/R-SPO-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Schizosaccharomyces pombe 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SPO-76031 https://reactome.org/PathwayBrowser/#/R-SPO-76031 2 H2O2 => O2 + 2 H2O IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-76590 https://reactome.org/PathwayBrowser/#/R-SPO-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8848215 https://reactome.org/PathwayBrowser/#/R-SPO-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8848484 https://reactome.org/PathwayBrowser/#/R-SPO-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Schizosaccharomyces pombe 15377 R-ALL-2022884 H2O [Golgi lumen] R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-ALL-2022884 H2O [Golgi lumen] R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8854255 https://reactome.org/PathwayBrowser/#/R-SPO-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8854329 https://reactome.org/PathwayBrowser/#/R-SPO-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Schizosaccharomyces pombe 15377 R-ALL-113518 H2O [nucleoplasm] R-SPO-8856951 https://reactome.org/PathwayBrowser/#/R-SPO-8856951 PP2A demethylation by PPME1 IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-8867344 https://reactome.org/PathwayBrowser/#/R-SPO-8867344 OMA1 hydrolyses OPA1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8869206 https://reactome.org/PathwayBrowser/#/R-SPO-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-8878654 https://reactome.org/PathwayBrowser/#/R-SPO-8878654 ACP6 hydrolyses MYS-LPA IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-893596 https://reactome.org/PathwayBrowser/#/R-SPO-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-8943279 https://reactome.org/PathwayBrowser/#/R-SPO-8943279 GGT dimers hydrolyse GSH IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-8955817 https://reactome.org/PathwayBrowser/#/R-SPO-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-8979996 https://reactome.org/PathwayBrowser/#/R-SPO-8979996 LIPs hydrolyze TG to DAG and LCFA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-8981637 https://reactome.org/PathwayBrowser/#/R-SPO-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9013022 https://reactome.org/PathwayBrowser/#/R-SPO-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9013111 https://reactome.org/PathwayBrowser/#/R-SPO-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9013161 https://reactome.org/PathwayBrowser/#/R-SPO-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9013437 https://reactome.org/PathwayBrowser/#/R-SPO-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9014641 https://reactome.org/PathwayBrowser/#/R-SPO-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9017488 https://reactome.org/PathwayBrowser/#/R-SPO-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9018745 https://reactome.org/PathwayBrowser/#/R-SPO-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9018814 https://reactome.org/PathwayBrowser/#/R-SPO-9018814 RHOT1 hydrolyzes GTP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9018826 https://reactome.org/PathwayBrowser/#/R-SPO-9018826 RHOT2 hydrolyzes GTP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9018862 https://reactome.org/PathwayBrowser/#/R-SPO-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9018877 https://reactome.org/PathwayBrowser/#/R-SPO-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9020252 https://reactome.org/PathwayBrowser/#/R-SPO-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9020253 https://reactome.org/PathwayBrowser/#/R-SPO-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9020257 https://reactome.org/PathwayBrowser/#/R-SPO-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9020258 https://reactome.org/PathwayBrowser/#/R-SPO-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9020270 https://reactome.org/PathwayBrowser/#/R-SPO-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9024890 https://reactome.org/PathwayBrowser/#/R-SPO-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Schizosaccharomyces pombe 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SPO-9036727 https://reactome.org/PathwayBrowser/#/R-SPO-9036727 GAA hydrolyzes lysosomal glycogen IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-936883 https://reactome.org/PathwayBrowser/#/R-SPO-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-936895 https://reactome.org/PathwayBrowser/#/R-SPO-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-939763 https://reactome.org/PathwayBrowser/#/R-SPO-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-947591 https://reactome.org/PathwayBrowser/#/R-SPO-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9624893 https://reactome.org/PathwayBrowser/#/R-SPO-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9635739 https://reactome.org/PathwayBrowser/#/R-SPO-9635739 PTPN7 dephosphorylates p-T,Y-MAPKs IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-965079 https://reactome.org/PathwayBrowser/#/R-SPO-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9653514 https://reactome.org/PathwayBrowser/#/R-SPO-9653514 USP17L2 deubiquitinates RCE1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9659680 https://reactome.org/PathwayBrowser/#/R-SPO-9659680 ABCB1 transports xenobiotics out of the cell IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-9673053 https://reactome.org/PathwayBrowser/#/R-SPO-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SPO-9673054 https://reactome.org/PathwayBrowser/#/R-SPO-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9674127 https://reactome.org/PathwayBrowser/#/R-SPO-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9693282 https://reactome.org/PathwayBrowser/#/R-SPO-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9750656 https://reactome.org/PathwayBrowser/#/R-SPO-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9753278 https://reactome.org/PathwayBrowser/#/R-SPO-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9753283 https://reactome.org/PathwayBrowser/#/R-SPO-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9753284 https://reactome.org/PathwayBrowser/#/R-SPO-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9753632 https://reactome.org/PathwayBrowser/#/R-SPO-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9753634 https://reactome.org/PathwayBrowser/#/R-SPO-9753634 GGT dimers hydrolyse APAP-SG IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9755030 https://reactome.org/PathwayBrowser/#/R-SPO-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9759454 https://reactome.org/PathwayBrowser/#/R-SPO-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9759461 https://reactome.org/PathwayBrowser/#/R-SPO-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-977324 https://reactome.org/PathwayBrowser/#/R-SPO-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-983144 https://reactome.org/PathwayBrowser/#/R-SPO-983144 Transport of Antigen peptide in to ER IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9837419 https://reactome.org/PathwayBrowser/#/R-SPO-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-9838004 https://reactome.org/PathwayBrowser/#/R-SPO-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-9838081 https://reactome.org/PathwayBrowser/#/R-SPO-9838081 LONP1 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-9839105 https://reactome.org/PathwayBrowser/#/R-SPO-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Schizosaccharomyces pombe 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SPO-9839113 https://reactome.org/PathwayBrowser/#/R-SPO-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Schizosaccharomyces pombe 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SPO-9840949 https://reactome.org/PathwayBrowser/#/R-SPO-9840949 ARSA removes sulfate from SM3 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9853385 https://reactome.org/PathwayBrowser/#/R-SPO-9853385 PPP1CC dephosphorylates PLK1 IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9912636 https://reactome.org/PathwayBrowser/#/R-SPO-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9912655 https://reactome.org/PathwayBrowser/#/R-SPO-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9912747 https://reactome.org/PathwayBrowser/#/R-SPO-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Schizosaccharomyces pombe 15377 R-ALL-29356 H2O [cytosol] R-SPO-9912751 https://reactome.org/PathwayBrowser/#/R-SPO-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Schizosaccharomyces pombe 15377 R-ALL-109276 H2O [extracellular region] R-SSC-109278 https://reactome.org/PathwayBrowser/#/R-SSC-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-109291 https://reactome.org/PathwayBrowser/#/R-SSC-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109380 https://reactome.org/PathwayBrowser/#/R-SSC-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109387 https://reactome.org/PathwayBrowser/#/R-SSC-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109415 https://reactome.org/PathwayBrowser/#/R-SSC-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109449 https://reactome.org/PathwayBrowser/#/R-SSC-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109470 https://reactome.org/PathwayBrowser/#/R-SSC-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-109480 https://reactome.org/PathwayBrowser/#/R-SSC-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-109514 https://reactome.org/PathwayBrowser/#/R-SSC-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111742 https://reactome.org/PathwayBrowser/#/R-SSC-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111751 https://reactome.org/PathwayBrowser/#/R-SSC-111751 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111804 https://reactome.org/PathwayBrowser/#/R-SSC-111804 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111879 https://reactome.org/PathwayBrowser/#/R-SSC-111879 PIP2 hydrolysis IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111955 https://reactome.org/PathwayBrowser/#/R-SSC-111955 cAMP hydrolysis by Cam-PDE 1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-111962 https://reactome.org/PathwayBrowser/#/R-SSC-111962 PDE4A,C,D hydrolyse cAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-112037 https://reactome.org/PathwayBrowser/#/R-SSC-112037 Inactivation of PLC beta IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-113503 https://reactome.org/PathwayBrowser/#/R-SSC-113503 PP2A mediated localization of RB1 protein in chromatin IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1169192 https://reactome.org/PathwayBrowser/#/R-SSC-1169192 PTP1B dephosphorylates GHR IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1183128 https://reactome.org/PathwayBrowser/#/R-SSC-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1237129 https://reactome.org/PathwayBrowser/#/R-SSC-1237129 Acireductone is created IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1247910 https://reactome.org/PathwayBrowser/#/R-SSC-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1247935 https://reactome.org/PathwayBrowser/#/R-SSC-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-1363274 https://reactome.org/PathwayBrowser/#/R-SSC-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-1363276 https://reactome.org/PathwayBrowser/#/R-SSC-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1369028 https://reactome.org/PathwayBrowser/#/R-SSC-1369028 ABCAs mediate lipid efflux IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1369052 https://reactome.org/PathwayBrowser/#/R-SSC-1369052 ABCAs mediate lipid influx IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1369065 https://reactome.org/PathwayBrowser/#/R-SSC-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-139906 https://reactome.org/PathwayBrowser/#/R-SSC-139906 Activation of BAD by calcineurin IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-140359 https://reactome.org/PathwayBrowser/#/R-SSC-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-141186 https://reactome.org/PathwayBrowser/#/R-SSC-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-141200 https://reactome.org/PathwayBrowser/#/R-SSC-141200 MAOB:FAD oxidatively deaminates of PEA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-141202 https://reactome.org/PathwayBrowser/#/R-SSC-141202 MAOB:FAD oxidatively deaminates TYR IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-141341 https://reactome.org/PathwayBrowser/#/R-SSC-141341 SMOX-3 oxidises SPN to SPM IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-141348 https://reactome.org/PathwayBrowser/#/R-SSC-141348 PAO:FAD oxidises NASPM to PTCN IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-141351 https://reactome.org/PathwayBrowser/#/R-SSC-141351 PAOX:FAD oxidises NASPN to SPM IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1454916 https://reactome.org/PathwayBrowser/#/R-SSC-1454916 The ABCC family mediates organic anion transport IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1467457 https://reactome.org/PathwayBrowser/#/R-SSC-1467457 ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1467466 https://reactome.org/PathwayBrowser/#/R-SSC-1467466 ABCA4 mediates atRAL transport IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1474146 https://reactome.org/PathwayBrowser/#/R-SSC-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482543 https://reactome.org/PathwayBrowser/#/R-SSC-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482604 https://reactome.org/PathwayBrowser/#/R-SSC-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482612 https://reactome.org/PathwayBrowser/#/R-SSC-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482656 https://reactome.org/PathwayBrowser/#/R-SSC-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482679 https://reactome.org/PathwayBrowser/#/R-SSC-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482685 https://reactome.org/PathwayBrowser/#/R-SSC-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1482745 https://reactome.org/PathwayBrowser/#/R-SSC-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1482759 https://reactome.org/PathwayBrowser/#/R-SSC-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482771 https://reactome.org/PathwayBrowser/#/R-SSC-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482776 https://reactome.org/PathwayBrowser/#/R-SSC-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482777 https://reactome.org/PathwayBrowser/#/R-SSC-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482811 https://reactome.org/PathwayBrowser/#/R-SSC-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482816 https://reactome.org/PathwayBrowser/#/R-SSC-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482825 https://reactome.org/PathwayBrowser/#/R-SSC-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482828 https://reactome.org/PathwayBrowser/#/R-SSC-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1482847 https://reactome.org/PathwayBrowser/#/R-SSC-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482856 https://reactome.org/PathwayBrowser/#/R-SSC-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482862 https://reactome.org/PathwayBrowser/#/R-SSC-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482868 https://reactome.org/PathwayBrowser/#/R-SSC-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482884 https://reactome.org/PathwayBrowser/#/R-SSC-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482887 https://reactome.org/PathwayBrowser/#/R-SSC-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482897 https://reactome.org/PathwayBrowser/#/R-SSC-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482900 https://reactome.org/PathwayBrowser/#/R-SSC-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482907 https://reactome.org/PathwayBrowser/#/R-SSC-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482920 https://reactome.org/PathwayBrowser/#/R-SSC-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1482932 https://reactome.org/PathwayBrowser/#/R-SSC-1482932 PI is hydrolyzed to 2-acyl LPI by PLA2[13] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1483096 https://reactome.org/PathwayBrowser/#/R-SSC-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1483159 https://reactome.org/PathwayBrowser/#/R-SSC-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1483182 https://reactome.org/PathwayBrowser/#/R-SSC-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1483203 https://reactome.org/PathwayBrowser/#/R-SSC-1483203 PA is dephosphorylated to DAG by LPIN IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-159425 https://reactome.org/PathwayBrowser/#/R-SSC-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159752 https://reactome.org/PathwayBrowser/#/R-SSC-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159761 https://reactome.org/PathwayBrowser/#/R-SSC-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159795 https://reactome.org/PathwayBrowser/#/R-SSC-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159803 https://reactome.org/PathwayBrowser/#/R-SSC-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159819 https://reactome.org/PathwayBrowser/#/R-SSC-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-159826 https://reactome.org/PathwayBrowser/#/R-SSC-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602368 https://reactome.org/PathwayBrowser/#/R-SSC-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602374 https://reactome.org/PathwayBrowser/#/R-SSC-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602377 https://reactome.org/PathwayBrowser/#/R-SSC-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602398 https://reactome.org/PathwayBrowser/#/R-SSC-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602399 https://reactome.org/PathwayBrowser/#/R-SSC-1602399 PC is hydrolyzed to 1-acyl LPC by PLB1 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602417 https://reactome.org/PathwayBrowser/#/R-SSC-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-1602446 https://reactome.org/PathwayBrowser/#/R-SSC-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605591 https://reactome.org/PathwayBrowser/#/R-SSC-1605591 GBA1:SAPC hydrolyzes GlcCer IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605595 https://reactome.org/PathwayBrowser/#/R-SSC-1605595 bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605624 https://reactome.org/PathwayBrowser/#/R-SSC-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605632 https://reactome.org/PathwayBrowser/#/R-SSC-1605632 bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1605723 https://reactome.org/PathwayBrowser/#/R-SSC-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605724 https://reactome.org/PathwayBrowser/#/R-SSC-1605724 NEU1,4 hydrolyze PSAP(195-273):GM3:PE IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605736 https://reactome.org/PathwayBrowser/#/R-SSC-1605736 GLA hydrolyzes PSAP(195-273):Gb3Cer:PE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1605768 https://reactome.org/PathwayBrowser/#/R-SSC-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1606312 https://reactome.org/PathwayBrowser/#/R-SSC-1606312 GLB1 hydrolyzes SapB/C:LacCer IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1606564 https://reactome.org/PathwayBrowser/#/R-SSC-1606564 GALC hydrolyzes GalCer IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1606583 https://reactome.org/PathwayBrowser/#/R-SSC-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1606602 https://reactome.org/PathwayBrowser/#/R-SSC-1606602 ASAH1 hydrolyzes ceramide IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1606789 https://reactome.org/PathwayBrowser/#/R-SSC-1606789 ARSB hydrolyses DS IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-1606839 https://reactome.org/PathwayBrowser/#/R-SSC-1606839 ARSC hydrolyzes steroid sulfates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1614524 https://reactome.org/PathwayBrowser/#/R-SSC-1614524 PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1614544 https://reactome.org/PathwayBrowser/#/R-SSC-1614544 Sulfite is oxidized to sulfate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1614583 https://reactome.org/PathwayBrowser/#/R-SSC-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to pyruvate and H2S IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-162425 https://reactome.org/PathwayBrowser/#/R-SSC-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-162729 https://reactome.org/PathwayBrowser/#/R-SSC-162729 uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-162857 https://reactome.org/PathwayBrowser/#/R-SSC-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1630304 https://reactome.org/PathwayBrowser/#/R-SSC-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1630306 https://reactome.org/PathwayBrowser/#/R-SSC-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1638032 https://reactome.org/PathwayBrowser/#/R-SSC-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1638053 https://reactome.org/PathwayBrowser/#/R-SSC-1638053 HEXA cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1638821 https://reactome.org/PathwayBrowser/#/R-SSC-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-164832 https://reactome.org/PathwayBrowser/#/R-SSC-164832 ATPase synthesizes ATP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1667005 https://reactome.org/PathwayBrowser/#/R-SSC-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675795 https://reactome.org/PathwayBrowser/#/R-SSC-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675824 https://reactome.org/PathwayBrowser/#/R-SSC-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675836 https://reactome.org/PathwayBrowser/#/R-SSC-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675949 https://reactome.org/PathwayBrowser/#/R-SSC-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675988 https://reactome.org/PathwayBrowser/#/R-SSC-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1675994 https://reactome.org/PathwayBrowser/#/R-SSC-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676005 https://reactome.org/PathwayBrowser/#/R-SSC-1676005 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676020 https://reactome.org/PathwayBrowser/#/R-SSC-1676020 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676065 https://reactome.org/PathwayBrowser/#/R-SSC-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676105 https://reactome.org/PathwayBrowser/#/R-SSC-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676114 https://reactome.org/PathwayBrowser/#/R-SSC-1676114 PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676124 https://reactome.org/PathwayBrowser/#/R-SSC-1676124 PI4P is dephosphorylated to PI by SACM1L at the ER membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676141 https://reactome.org/PathwayBrowser/#/R-SSC-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676149 https://reactome.org/PathwayBrowser/#/R-SSC-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676162 https://reactome.org/PathwayBrowser/#/R-SSC-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676164 https://reactome.org/PathwayBrowser/#/R-SSC-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676174 https://reactome.org/PathwayBrowser/#/R-SSC-1676174 PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676177 https://reactome.org/PathwayBrowser/#/R-SSC-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676203 https://reactome.org/PathwayBrowser/#/R-SSC-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1676204 https://reactome.org/PathwayBrowser/#/R-SSC-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1678650 https://reactome.org/PathwayBrowser/#/R-SSC-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1678708 https://reactome.org/PathwayBrowser/#/R-SSC-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1678716 https://reactome.org/PathwayBrowser/#/R-SSC-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1678742 https://reactome.org/PathwayBrowser/#/R-SSC-1678742 NAGLU hydrolyses Heparan sulfate chain(4) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1678854 https://reactome.org/PathwayBrowser/#/R-SSC-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-170153 https://reactome.org/PathwayBrowser/#/R-SSC-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-170158 https://reactome.org/PathwayBrowser/#/R-SSC-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-170161 https://reactome.org/PathwayBrowser/#/R-SSC-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-173739 https://reactome.org/PathwayBrowser/#/R-SSC-173739 Spontaneous hydrolysis of C3 thioester IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-174110 https://reactome.org/PathwayBrowser/#/R-SSC-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-174124 https://reactome.org/PathwayBrowser/#/R-SSC-174124 Dephosphorylation of phospho-Cdh1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-174391 https://reactome.org/PathwayBrowser/#/R-SSC-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-174401 https://reactome.org/PathwayBrowser/#/R-SSC-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-174439 https://reactome.org/PathwayBrowser/#/R-SSC-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-176606 https://reactome.org/PathwayBrowser/#/R-SSC-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-177923 https://reactome.org/PathwayBrowser/#/R-SSC-177923 Sustained activation of SRC kinase by SHP2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-177924 https://reactome.org/PathwayBrowser/#/R-SSC-177924 Dephosphorylation of Gab1 by SHP2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-177926 https://reactome.org/PathwayBrowser/#/R-SSC-177926 Dephosphorylation of PAG by SHP2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-177935 https://reactome.org/PathwayBrowser/#/R-SSC-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1793182 https://reactome.org/PathwayBrowser/#/R-SSC-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1793186 https://reactome.org/PathwayBrowser/#/R-SSC-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1793207 https://reactome.org/PathwayBrowser/#/R-SSC-1793207 ARSB hydrolyses C4S/C6S chains IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-1793209 https://reactome.org/PathwayBrowser/#/R-SSC-1793209 HYAL1 hydrolyses Chondroitin chains IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855154 https://reactome.org/PathwayBrowser/#/R-SSC-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855159 https://reactome.org/PathwayBrowser/#/R-SSC-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-1855163 https://reactome.org/PathwayBrowser/#/R-SSC-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855165 https://reactome.org/PathwayBrowser/#/R-SSC-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855166 https://reactome.org/PathwayBrowser/#/R-SSC-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855171 https://reactome.org/PathwayBrowser/#/R-SSC-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855174 https://reactome.org/PathwayBrowser/#/R-SSC-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855177 https://reactome.org/PathwayBrowser/#/R-SSC-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855180 https://reactome.org/PathwayBrowser/#/R-SSC-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855198 https://reactome.org/PathwayBrowser/#/R-SSC-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-1855200 https://reactome.org/PathwayBrowser/#/R-SSC-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855202 https://reactome.org/PathwayBrowser/#/R-SSC-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855205 https://reactome.org/PathwayBrowser/#/R-SSC-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855208 https://reactome.org/PathwayBrowser/#/R-SSC-1855208 I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855210 https://reactome.org/PathwayBrowser/#/R-SSC-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855211 https://reactome.org/PathwayBrowser/#/R-SSC-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855213 https://reactome.org/PathwayBrowser/#/R-SSC-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855214 https://reactome.org/PathwayBrowser/#/R-SSC-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855218 https://reactome.org/PathwayBrowser/#/R-SSC-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855219 https://reactome.org/PathwayBrowser/#/R-SSC-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855221 https://reactome.org/PathwayBrowser/#/R-SSC-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855222 https://reactome.org/PathwayBrowser/#/R-SSC-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-1855225 https://reactome.org/PathwayBrowser/#/R-SSC-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1855232 https://reactome.org/PathwayBrowser/#/R-SSC-1855232 I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1861788 https://reactome.org/PathwayBrowser/#/R-SSC-1861788 GBA2 hydrolyzes GlcCer (plasma membrane) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-1861789 https://reactome.org/PathwayBrowser/#/R-SSC-1861789 GBA3 hydrolyzes GlcCer (cytosol) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-188979 https://reactome.org/PathwayBrowser/#/R-SSC-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-189053 https://reactome.org/PathwayBrowser/#/R-SSC-189053 Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-189062 https://reactome.org/PathwayBrowser/#/R-SSC-189062 lactose + H2O => D-glucose + D-galactose IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-189069 https://reactome.org/PathwayBrowser/#/R-SSC-189069 sucrose + H2O => glucose + fructose IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-189102 https://reactome.org/PathwayBrowser/#/R-SSC-189102 maltose + H2O => 2 D-glucose (maltase-glucoamylase) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-189398 https://reactome.org/PathwayBrowser/#/R-SSC-189398 HMOX1 dimer, HMOX2 cleave heme IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-189406 https://reactome.org/PathwayBrowser/#/R-SSC-189406 4 PBGs bind to form HMB IEA Sus scrofa 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-189488 https://reactome.org/PathwayBrowser/#/R-SSC-189488 UROS transforms HMB to URO3 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-191101 https://reactome.org/PathwayBrowser/#/R-SSC-191101 maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-191108 https://reactome.org/PathwayBrowser/#/R-SSC-191108 maltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-191114 https://reactome.org/PathwayBrowser/#/R-SSC-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-191116 https://reactome.org/PathwayBrowser/#/R-SSC-191116 maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192417 https://reactome.org/PathwayBrowser/#/R-SSC-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192422 https://reactome.org/PathwayBrowser/#/R-SSC-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192425 https://reactome.org/PathwayBrowser/#/R-SSC-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192430 https://reactome.org/PathwayBrowser/#/R-SSC-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192434 https://reactome.org/PathwayBrowser/#/R-SSC-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-192475 https://reactome.org/PathwayBrowser/#/R-SSC-192475 Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193362 https://reactome.org/PathwayBrowser/#/R-SSC-193362 ABCB11 transports bile salts from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-193385 https://reactome.org/PathwayBrowser/#/R-SSC-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193711 https://reactome.org/PathwayBrowser/#/R-SSC-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193727 https://reactome.org/PathwayBrowser/#/R-SSC-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193743 https://reactome.org/PathwayBrowser/#/R-SSC-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193766 https://reactome.org/PathwayBrowser/#/R-SSC-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-196950 https://reactome.org/PathwayBrowser/#/R-SSC-196950 2xTRAP hydrolyzes FMN to RIB IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-197186 https://reactome.org/PathwayBrowser/#/R-SSC-197186 NAPRT1 dimer transfers PRIB to NCA to form NAMN IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-199456 https://reactome.org/PathwayBrowser/#/R-SSC-199456 PTEN dephosphorylates PIP3 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-199959 https://reactome.org/PathwayBrowser/#/R-SSC-199959 ERKs are inactivated by protein phosphatase 2A IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2002466 https://reactome.org/PathwayBrowser/#/R-SSC-2002466 Formation of allysine by LOX IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-200661 https://reactome.org/PathwayBrowser/#/R-SSC-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-200740 https://reactome.org/PathwayBrowser/#/R-SSC-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-201035 https://reactome.org/PathwayBrowser/#/R-SSC-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-201790 https://reactome.org/PathwayBrowser/#/R-SSC-201790 DARPP-32 is dephosphorylated on Thr75 by PP2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-202214 https://reactome.org/PathwayBrowser/#/R-SSC-202214 Dephosphorylation of Lck-pY505 by CD45 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022368 https://reactome.org/PathwayBrowser/#/R-SSC-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-202237 https://reactome.org/PathwayBrowser/#/R-SSC-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022378 https://reactome.org/PathwayBrowser/#/R-SSC-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022379 https://reactome.org/PathwayBrowser/#/R-SSC-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022381 https://reactome.org/PathwayBrowser/#/R-SSC-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022383 https://reactome.org/PathwayBrowser/#/R-SSC-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022396 https://reactome.org/PathwayBrowser/#/R-SSC-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022398 https://reactome.org/PathwayBrowser/#/R-SSC-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022399 https://reactome.org/PathwayBrowser/#/R-SSC-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022403 https://reactome.org/PathwayBrowser/#/R-SSC-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022405 https://reactome.org/PathwayBrowser/#/R-SSC-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022411 https://reactome.org/PathwayBrowser/#/R-SSC-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2022412 https://reactome.org/PathwayBrowser/#/R-SSC-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-ALL-2022884 H2O [Golgi lumen] R-SSC-2022887 https://reactome.org/PathwayBrowser/#/R-SSC-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2023971 https://reactome.org/PathwayBrowser/#/R-SSC-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2023973 https://reactome.org/PathwayBrowser/#/R-SSC-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-202407 https://reactome.org/PathwayBrowser/#/R-SSC-202407 PLC-gamma1 hydrolyses PIP2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2029468 https://reactome.org/PathwayBrowser/#/R-SSC-2029468 Conversion of PA into DAG by PAP-1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2029471 https://reactome.org/PathwayBrowser/#/R-SSC-2029471 Hydrolysis of PC to PA by PLD IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2029475 https://reactome.org/PathwayBrowser/#/R-SSC-2029475 Production of AA by iPLA2 upon FCGR activation IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 Depalmitoylation of eNOS IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-203797 https://reactome.org/PathwayBrowser/#/R-SSC-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-204169 https://reactome.org/PathwayBrowser/#/R-SSC-204169 PDP1,2 dephosphorylate p-lipo-PDH IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046083 https://reactome.org/PathwayBrowser/#/R-SSC-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046084 https://reactome.org/PathwayBrowser/#/R-SSC-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046088 https://reactome.org/PathwayBrowser/#/R-SSC-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046089 https://reactome.org/PathwayBrowser/#/R-SSC-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046090 https://reactome.org/PathwayBrowser/#/R-SSC-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046092 https://reactome.org/PathwayBrowser/#/R-SSC-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046094 https://reactome.org/PathwayBrowser/#/R-SSC-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046095 https://reactome.org/PathwayBrowser/#/R-SSC-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046096 https://reactome.org/PathwayBrowser/#/R-SSC-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046097 https://reactome.org/PathwayBrowser/#/R-SSC-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2046100 https://reactome.org/PathwayBrowser/#/R-SSC-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2065355 https://reactome.org/PathwayBrowser/#/R-SSC-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2065357 https://reactome.org/PathwayBrowser/#/R-SSC-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-2066779 https://reactome.org/PathwayBrowser/#/R-SSC-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2090037 https://reactome.org/PathwayBrowser/#/R-SSC-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2090038 https://reactome.org/PathwayBrowser/#/R-SSC-2090038 NAGLU hydrolyses heparan chain(2) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2090043 https://reactome.org/PathwayBrowser/#/R-SSC-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2090079 https://reactome.org/PathwayBrowser/#/R-SSC-2090079 GLB1 hydrolyses linker chain(2) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-209055 https://reactome.org/PathwayBrowser/#/R-SSC-209055 PPM1A dephosphorylates nuclear SMAD2/3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15377 R-ALL-351603 H2O [secretory granule lumen] R-SSC-209891 https://reactome.org/PathwayBrowser/#/R-SSC-209891 Dopamine is oxidised to noradrenaline IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2105001 https://reactome.org/PathwayBrowser/#/R-SSC-2105001 HEXA cleaves the terminal GalNAc from DS IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2130725 https://reactome.org/PathwayBrowser/#/R-SSC-2130725 Internalization of MHC II:Ii clathrin coated vesicle IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2160492 https://reactome.org/PathwayBrowser/#/R-SSC-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2160874 https://reactome.org/PathwayBrowser/#/R-SSC-2160874 HYAL1 hydrolyses (HA)50 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161195 https://reactome.org/PathwayBrowser/#/R-SSC-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161775 https://reactome.org/PathwayBrowser/#/R-SSC-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161791 https://reactome.org/PathwayBrowser/#/R-SSC-2161791 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161959 https://reactome.org/PathwayBrowser/#/R-SSC-2161959 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161961 https://reactome.org/PathwayBrowser/#/R-SSC-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2161999 https://reactome.org/PathwayBrowser/#/R-SSC-2161999 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-2162187 https://reactome.org/PathwayBrowser/#/R-SSC-2162187 COQ6 hydroxylates DHB IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2162225 https://reactome.org/PathwayBrowser/#/R-SSC-2162225 HEXA cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2162226 https://reactome.org/PathwayBrowser/#/R-SSC-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-2162227 https://reactome.org/PathwayBrowser/#/R-SSC-2162227 GUSB tetramer hydrolyses (HA)2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-216723 https://reactome.org/PathwayBrowser/#/R-SSC-216723 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-216757 https://reactome.org/PathwayBrowser/#/R-SSC-216757 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2187401 https://reactome.org/PathwayBrowser/#/R-SSC-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-2309773 https://reactome.org/PathwayBrowser/#/R-SSC-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2393939 https://reactome.org/PathwayBrowser/#/R-SSC-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-2393954 https://reactome.org/PathwayBrowser/#/R-SSC-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2395340 https://reactome.org/PathwayBrowser/#/R-SSC-2395340 Formation of hydroxyallysine by LOX IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2408551 https://reactome.org/PathwayBrowser/#/R-SSC-2408551 SeMet is converted to AdoSeMet by MAT IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2454118 https://reactome.org/PathwayBrowser/#/R-SSC-2454118 11cRAL binds to opsin to form 11c-retinyl:RHO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2465924 https://reactome.org/PathwayBrowser/#/R-SSC-2465924 OPN1LW binds 11cRAL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2466085 https://reactome.org/PathwayBrowser/#/R-SSC-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2529015 https://reactome.org/PathwayBrowser/#/R-SSC-2529015 Dephosphorylation of CK2-modified condensin I IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2584246 https://reactome.org/PathwayBrowser/#/R-SSC-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2632521 https://reactome.org/PathwayBrowser/#/R-SSC-2632521 at-retinyl is hydrolysed from p-MII:SAG to release atRAL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-265783 https://reactome.org/PathwayBrowser/#/R-SSC-265783 ABCG5:ABCG8 transports sterols from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-266012 https://reactome.org/PathwayBrowser/#/R-SSC-266012 LTD4 is converted to LTE4 by DPEP1/2 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-266046 https://reactome.org/PathwayBrowser/#/R-SSC-266046 GGT1, 5 dimers hydrolyse LTC4 to LTD4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-266051 https://reactome.org/PathwayBrowser/#/R-SSC-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-266070 https://reactome.org/PathwayBrowser/#/R-SSC-266070 LTC4 is exported from the cytosol by ABCC1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-266072 https://reactome.org/PathwayBrowser/#/R-SSC-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-266082 https://reactome.org/PathwayBrowser/#/R-SSC-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2730847 https://reactome.org/PathwayBrowser/#/R-SSC-2730847 Hydrolysis of PIP2 by PLCG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2730849 https://reactome.org/PathwayBrowser/#/R-SSC-2730849 Calcineurin binds and dephosphorylates NFAT IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-2855047 https://reactome.org/PathwayBrowser/#/R-SSC-2855047 Hydrolysis of internal thioester in C4b IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-2995330 https://reactome.org/PathwayBrowser/#/R-SSC-2995330 COX10 transforms heme to heme O IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-2995334 https://reactome.org/PathwayBrowser/#/R-SSC-2995334 COX15 transforms heme O to heme A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-2995388 https://reactome.org/PathwayBrowser/#/R-SSC-2995388 PP2A dephosphorylates BANF1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3002811 https://reactome.org/PathwayBrowser/#/R-SSC-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3095901 https://reactome.org/PathwayBrowser/#/R-SSC-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3204311 https://reactome.org/PathwayBrowser/#/R-SSC-3204311 AOX1 oxidises PXL to PDXate IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3215295 https://reactome.org/PathwayBrowser/#/R-SSC-3215295 USP7 deubiquitinates MDM2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3215310 https://reactome.org/PathwayBrowser/#/R-SSC-3215310 USP7 deubiquitinates TP53 and counteracts MDM2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3247569 https://reactome.org/PathwayBrowser/#/R-SSC-3247569 PADI4 deiminates Histones IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-3262512 https://reactome.org/PathwayBrowser/#/R-SSC-3262512 G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-3266566 https://reactome.org/PathwayBrowser/#/R-SSC-3266566 G6PC2 hydrolyzes G6P to form Glc and Pi (islet) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-3322995 https://reactome.org/PathwayBrowser/#/R-SSC-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-3323013 https://reactome.org/PathwayBrowser/#/R-SSC-3323013 GPX1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3341277 https://reactome.org/PathwayBrowser/#/R-SSC-3341277 GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-3341296 https://reactome.org/PathwayBrowser/#/R-SSC-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3341343 https://reactome.org/PathwayBrowser/#/R-SSC-3341343 PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-3341397 https://reactome.org/PathwayBrowser/#/R-SSC-3341397 GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3343700 https://reactome.org/PathwayBrowser/#/R-SSC-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3371467 https://reactome.org/PathwayBrowser/#/R-SSC-3371467 SIRT1 deacetylates HSF1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-350604 https://reactome.org/PathwayBrowser/#/R-SSC-350604 Agmatine + H2O <=> putrescine + urea IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3640872 https://reactome.org/PathwayBrowser/#/R-SSC-3640872 USP34 deubiquitinates AXIN1,AXIN2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3697882 https://reactome.org/PathwayBrowser/#/R-SSC-3697882 PRDX5 reduces peroxynitrite to nitrite using TXN IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-3697894 https://reactome.org/PathwayBrowser/#/R-SSC-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-372519 https://reactome.org/PathwayBrowser/#/R-SSC-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-374909 https://reactome.org/PathwayBrowser/#/R-SSC-374909 Catabolism of Noradrenaline IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3769447 https://reactome.org/PathwayBrowser/#/R-SSC-3769447 HDAC1:2-containing complex deacetylate histones IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-377643 https://reactome.org/PathwayBrowser/#/R-SSC-377643 Dephosphorylation of inactive SRC by PTPB1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3777129 https://reactome.org/PathwayBrowser/#/R-SSC-3777129 HDAC3 containing complexes deacetylate histone IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3781011 https://reactome.org/PathwayBrowser/#/R-SSC-3781011 EPM2A dimer dephosphorylates phosphoglycogen-GYG2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-3781018 https://reactome.org/PathwayBrowser/#/R-SSC-3781018 EPM2A dimer dephosphorylates phosphoglycogen-GYG1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3782637 https://reactome.org/PathwayBrowser/#/R-SSC-3782637 HDAC8 deacetylates histones IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-3782655 https://reactome.org/PathwayBrowser/#/R-SSC-3782655 HDAC10 deacetylates histone IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-379382 https://reactome.org/PathwayBrowser/#/R-SSC-379382 MAOA:FAD deaminates DA to DOPAC IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-379395 https://reactome.org/PathwayBrowser/#/R-SSC-379395 MAOA:FAD deaminates 3MT to HVA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-380949 https://reactome.org/PathwayBrowser/#/R-SSC-380949 AMPK is dephosphorylated IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-382553 https://reactome.org/PathwayBrowser/#/R-SSC-382553 ABCA7:Apo1A-mediated phospholipid efflux IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-382560 https://reactome.org/PathwayBrowser/#/R-SSC-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-382575 https://reactome.org/PathwayBrowser/#/R-SSC-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-383190 https://reactome.org/PathwayBrowser/#/R-SSC-383190 HCO3- transport through ion channel IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-389821 https://reactome.org/PathwayBrowser/#/R-SSC-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-389862 https://reactome.org/PathwayBrowser/#/R-SSC-389862 Conversion of glyoxylate to oxalate IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-390393 https://reactome.org/PathwayBrowser/#/R-SSC-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-399998 https://reactome.org/PathwayBrowser/#/R-SSC-399998 Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4084976 https://reactome.org/PathwayBrowser/#/R-SSC-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4084989 https://reactome.org/PathwayBrowser/#/R-SSC-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4084994 https://reactome.org/PathwayBrowser/#/R-SSC-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-4084999 https://reactome.org/PathwayBrowser/#/R-SSC-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4085021 https://reactome.org/PathwayBrowser/#/R-SSC-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4085029 https://reactome.org/PathwayBrowser/#/R-SSC-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4086392 https://reactome.org/PathwayBrowser/#/R-SSC-4086392 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-4088141 https://reactome.org/PathwayBrowser/#/R-SSC-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4093339 https://reactome.org/PathwayBrowser/#/R-SSC-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-416559 https://reactome.org/PathwayBrowser/#/R-SSC-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-418553 https://reactome.org/PathwayBrowser/#/R-SSC-418553 cAMP degradation by Phosphodiesterases IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428205 https://reactome.org/PathwayBrowser/#/R-SSC-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428231 https://reactome.org/PathwayBrowser/#/R-SSC-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428262 https://reactome.org/PathwayBrowser/#/R-SSC-428262 ACER3 hydrolyzes phytoceramide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428664 https://reactome.org/PathwayBrowser/#/R-SSC-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-428690 https://reactome.org/PathwayBrowser/#/R-SSC-428690 PLPP1 dephosphorylates extracellular sphingosine-1-phosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-428696 https://reactome.org/PathwayBrowser/#/R-SSC-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-429860 https://reactome.org/PathwayBrowser/#/R-SSC-429860 DCP1-DCP2 complex decaps mRNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-429955 https://reactome.org/PathwayBrowser/#/R-SSC-429955 CCR4-NOT complex deadenylates mRNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-429961 https://reactome.org/PathwayBrowser/#/R-SSC-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-429992 https://reactome.org/PathwayBrowser/#/R-SSC-429992 PARN deadenylates mRNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-430021 https://reactome.org/PathwayBrowser/#/R-SSC-430021 PAN2-PAN3 complex partially deadenylates mRNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-430028 https://reactome.org/PathwayBrowser/#/R-SSC-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-432010 https://reactome.org/PathwayBrowser/#/R-SSC-432010 Aquaporin-1 passively transports water into cell IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-432010 https://reactome.org/PathwayBrowser/#/R-SSC-432010 Aquaporin-1 passively transports water into cell IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-432054 https://reactome.org/PathwayBrowser/#/R-SSC-432054 Aquaporin-1 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-432054 https://reactome.org/PathwayBrowser/#/R-SSC-432054 Aquaporin-1 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-432065 https://reactome.org/PathwayBrowser/#/R-SSC-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-432065 https://reactome.org/PathwayBrowser/#/R-SSC-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-432067 https://reactome.org/PathwayBrowser/#/R-SSC-432067 Aquaporin-4 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-432067 https://reactome.org/PathwayBrowser/#/R-SSC-432067 Aquaporin-4 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-4419948 https://reactome.org/PathwayBrowser/#/R-SSC-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-445714 https://reactome.org/PathwayBrowser/#/R-SSC-445714 Aquaporin-3 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-445714 https://reactome.org/PathwayBrowser/#/R-SSC-445714 Aquaporin-3 passively transports water out of cell IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-449937 https://reactome.org/PathwayBrowser/#/R-SSC-449937 pyrophosphate + H2O => 2 orthophosphate [mitochondrial] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-452036 https://reactome.org/PathwayBrowser/#/R-SSC-452036 arginine + H2O => ornithine + urea [ARG2] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4551451 https://reactome.org/PathwayBrowser/#/R-SSC-4551451 Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-4641236 https://reactome.org/PathwayBrowser/#/R-SSC-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-507868 https://reactome.org/PathwayBrowser/#/R-SSC-507868 Aquaporins passively transport water into cells IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-507870 https://reactome.org/PathwayBrowser/#/R-SSC-507870 Aquaporins passively transport water out of cells IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5221130 https://reactome.org/PathwayBrowser/#/R-SSC-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5223313 https://reactome.org/PathwayBrowser/#/R-SSC-5223313 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5223317 https://reactome.org/PathwayBrowser/#/R-SSC-5223317 ABCB9 transports peptides from cytosol to lysosomal lumen IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5251955 https://reactome.org/PathwayBrowser/#/R-SSC-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5251959 https://reactome.org/PathwayBrowser/#/R-SSC-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5251989 https://reactome.org/PathwayBrowser/#/R-SSC-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5362459 https://reactome.org/PathwayBrowser/#/R-SSC-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5433072 https://reactome.org/PathwayBrowser/#/R-SSC-5433072 GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5433074 https://reactome.org/PathwayBrowser/#/R-SSC-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-548843 https://reactome.org/PathwayBrowser/#/R-SSC-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5603114 https://reactome.org/PathwayBrowser/#/R-SSC-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5607735 https://reactome.org/PathwayBrowser/#/R-SSC-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5618093 https://reactome.org/PathwayBrowser/#/R-SSC-5618093 ATP hydrolysis by HSP90 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5623513 https://reactome.org/PathwayBrowser/#/R-SSC-5623513 ASAP1 stimulates GTPase activity of ARF4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5628905 https://reactome.org/PathwayBrowser/#/R-SSC-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5631885 https://reactome.org/PathwayBrowser/#/R-SSC-5631885 PRDX1 overoxidizes IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5649705 https://reactome.org/PathwayBrowser/#/R-SSC-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5651828 https://reactome.org/PathwayBrowser/#/R-SSC-5651828 PARG dePARylates PARP1,PARP2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5653770 https://reactome.org/PathwayBrowser/#/R-SSC-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5653786 https://reactome.org/PathwayBrowser/#/R-SSC-5653786 USP43 deISGylates ISG:K164,ISG:K168-PCNA IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5659861 https://reactome.org/PathwayBrowser/#/R-SSC-5659861 isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) IEA Sus scrofa 15377 R-ALL-5668574 H2O [melanosome lumen] R-SSC-5662692 https://reactome.org/PathwayBrowser/#/R-SSC-5662692 Dopa is oxidized to dopaquinone by TYR IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5665809 https://reactome.org/PathwayBrowser/#/R-SSC-5665809 SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5672957 https://reactome.org/PathwayBrowser/#/R-SSC-5672957 PP2A dephosphorylates KSR1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5672961 https://reactome.org/PathwayBrowser/#/R-SSC-5672961 PP2A dephosphorylates inactive RAFs IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5675373 https://reactome.org/PathwayBrowser/#/R-SSC-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5675376 https://reactome.org/PathwayBrowser/#/R-SSC-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5675431 https://reactome.org/PathwayBrowser/#/R-SSC-5675431 PP2A dephosphorylates RAF1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5675433 https://reactome.org/PathwayBrowser/#/R-SSC-5675433 PP5 dephosphorylates RAF1 S338 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5676637 https://reactome.org/PathwayBrowser/#/R-SSC-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5678706 https://reactome.org/PathwayBrowser/#/R-SSC-5678706 ABCB4 transports PC from plasma membrane to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5678863 https://reactome.org/PathwayBrowser/#/R-SSC-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5679041 https://reactome.org/PathwayBrowser/#/R-SSC-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5682285 https://reactome.org/PathwayBrowser/#/R-SSC-5682285 ABCA12 transports lipids from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5683405 https://reactome.org/PathwayBrowser/#/R-SSC-5683405 PPP5C dephosphorylates TP53BP1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5683714 https://reactome.org/PathwayBrowser/#/R-SSC-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5683967 https://reactome.org/PathwayBrowser/#/R-SSC-5683967 EYA1-4 dephosphorylates tyrosine Y142 of H2AFX IEA Sus scrofa 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-SSC-5684864 https://reactome.org/PathwayBrowser/#/R-SSC-5684864 NAPSA, CTSH, PGA3-5 cleave pro-SFTPB IEA Sus scrofa 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-SSC-5685902 https://reactome.org/PathwayBrowser/#/R-SSC-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5685994 https://reactome.org/PathwayBrowser/#/R-SSC-5685994 Long-range resection of DNA DSBs by EXO1 or DNA2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5687464 https://reactome.org/PathwayBrowser/#/R-SSC-5687464 MRN and RBBP8 resect DNA DSBs in MMEJ IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5687664 https://reactome.org/PathwayBrowser/#/R-SSC-5687664 FEN1 cleaves displaced ssDNA flaps during MMEJ IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5687758 https://reactome.org/PathwayBrowser/#/R-SSC-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5688797 https://reactome.org/PathwayBrowser/#/R-SSC-5688797 ATXN3 family cleave Ub chains IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5689000 https://reactome.org/PathwayBrowser/#/R-SSC-5689000 AADAC deacetylates PHEN IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5689950 https://reactome.org/PathwayBrowser/#/R-SSC-5689950 USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5689973 https://reactome.org/PathwayBrowser/#/R-SSC-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690043 https://reactome.org/PathwayBrowser/#/R-SSC-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5690066 https://reactome.org/PathwayBrowser/#/R-SSC-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5690080 https://reactome.org/PathwayBrowser/#/R-SSC-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690152 https://reactome.org/PathwayBrowser/#/R-SSC-5690152 USP5 cleaves polyubiquitin IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5690157 https://reactome.org/PathwayBrowser/#/R-SSC-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690159 https://reactome.org/PathwayBrowser/#/R-SSC-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690196 https://reactome.org/PathwayBrowser/#/R-SSC-5690196 USP8 deubiquitinates RNF128 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690319 https://reactome.org/PathwayBrowser/#/R-SSC-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-5690517 https://reactome.org/PathwayBrowser/#/R-SSC-5690517 PPT1 hydrolyses palmitoylated proteins IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5690759 https://reactome.org/PathwayBrowser/#/R-SSC-5690759 BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5690790 https://reactome.org/PathwayBrowser/#/R-SSC-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690808 https://reactome.org/PathwayBrowser/#/R-SSC-5690808 UCHL3, SENP8 cleave NEDD8 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690856 https://reactome.org/PathwayBrowser/#/R-SSC-5690856 TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5690870 https://reactome.org/PathwayBrowser/#/R-SSC-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5691381 https://reactome.org/PathwayBrowser/#/R-SSC-5691381 MYSM1 deubiquitinates Histone H2A IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5691411 https://reactome.org/PathwayBrowser/#/R-SSC-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5691439 https://reactome.org/PathwayBrowser/#/R-SSC-5691439 BRISC complex deubiquitinates NLRP3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5691507 https://reactome.org/PathwayBrowser/#/R-SSC-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5691512 https://reactome.org/PathwayBrowser/#/R-SSC-5691512 APEH hydrolyses NAc-Ser-protein IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5692462 https://reactome.org/PathwayBrowser/#/R-SSC-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5692480 https://reactome.org/PathwayBrowser/#/R-SSC-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5692754 https://reactome.org/PathwayBrowser/#/R-SSC-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5693153 https://reactome.org/PathwayBrowser/#/R-SSC-5693153 PPM1K dephosphorylates p-BCKDH IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5693346 https://reactome.org/PathwayBrowser/#/R-SSC-5693346 CECRI deaminates Ade-Rib to Ino IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5693608 https://reactome.org/PathwayBrowser/#/R-SSC-5693608 Initial resection of double-strand break ends IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-5693724 https://reactome.org/PathwayBrowser/#/R-SSC-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5693742 https://reactome.org/PathwayBrowser/#/R-SSC-5693742 FAAH hydrolyses AEA to AA and ETA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5693783 https://reactome.org/PathwayBrowser/#/R-SSC-5693783 NAALADases hydrolyse NAAG IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-5693807 https://reactome.org/PathwayBrowser/#/R-SSC-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694077 https://reactome.org/PathwayBrowser/#/R-SSC-5694077 EPHX1 hydrates BaP4,5O to BaP4,5-DHD IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5694109 https://reactome.org/PathwayBrowser/#/R-SSC-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694126 https://reactome.org/PathwayBrowser/#/R-SSC-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5694137 https://reactome.org/PathwayBrowser/#/R-SSC-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694421 https://reactome.org/PathwayBrowser/#/R-SSC-5694421 PP6 dephosphorylates SEC24 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694485 https://reactome.org/PathwayBrowser/#/R-SSC-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5694563 https://reactome.org/PathwayBrowser/#/R-SSC-5694563 ABHD10 hydrolyses MPAG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5694583 https://reactome.org/PathwayBrowser/#/R-SSC-5694583 ABHD4 hydrolyses NAPE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5695964 https://reactome.org/PathwayBrowser/#/R-SSC-5695964 ABHD14B hydrolyses PNPB IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696049 https://reactome.org/PathwayBrowser/#/R-SSC-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696119 https://reactome.org/PathwayBrowser/#/R-SSC-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5696197 https://reactome.org/PathwayBrowser/#/R-SSC-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696230 https://reactome.org/PathwayBrowser/#/R-SSC-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696365 https://reactome.org/PathwayBrowser/#/R-SSC-5696365 ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5696408 https://reactome.org/PathwayBrowser/#/R-SSC-5696408 PXLP-K278-PHYKPL tetramer hydrolyses 5PHL IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-5696415 https://reactome.org/PathwayBrowser/#/R-SSC-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696465 https://reactome.org/PathwayBrowser/#/R-SSC-5696465 USP45 deubiquitinates ERCC1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696534 https://reactome.org/PathwayBrowser/#/R-SSC-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696564 https://reactome.org/PathwayBrowser/#/R-SSC-5696564 USP25 deubiquitinates DDX58 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696600 https://reactome.org/PathwayBrowser/#/R-SSC-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696605 https://reactome.org/PathwayBrowser/#/R-SSC-5696605 USP12, USP26 deubiquitinate AR IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696627 https://reactome.org/PathwayBrowser/#/R-SSC-5696627 CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696872 https://reactome.org/PathwayBrowser/#/R-SSC-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696914 https://reactome.org/PathwayBrowser/#/R-SSC-5696914 USP28 deubiquitinates CLSPN and MYC IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696945 https://reactome.org/PathwayBrowser/#/R-SSC-5696945 USP33 deubiquitinates CCP110,ARRB IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696947 https://reactome.org/PathwayBrowser/#/R-SSC-5696947 USP47 deubiquitinates POLB IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696958 https://reactome.org/PathwayBrowser/#/R-SSC-5696958 USP44 deubiquitinates CDC20 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696960 https://reactome.org/PathwayBrowser/#/R-SSC-5696960 USP49 deubiquitinates H2B IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-5696968 https://reactome.org/PathwayBrowser/#/R-SSC-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5696997 https://reactome.org/PathwayBrowser/#/R-SSC-5696997 USP24 deubiquitinates DDB2 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-5697009 https://reactome.org/PathwayBrowser/#/R-SSC-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6781764 https://reactome.org/PathwayBrowser/#/R-SSC-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6781779 https://reactome.org/PathwayBrowser/#/R-SSC-6781779 USP13 deubiquitinates BECN1,USP10 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6781814 https://reactome.org/PathwayBrowser/#/R-SSC-6781814 USP19 deubiquitinates RNF123 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6781897 https://reactome.org/PathwayBrowser/#/R-SSC-6781897 USP11 deubiquitinates NFKBIA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6782069 https://reactome.org/PathwayBrowser/#/R-SSC-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6782106 https://reactome.org/PathwayBrowser/#/R-SSC-6782106 USP10 deubiquitinates SNX3, CFTR IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6782628 https://reactome.org/PathwayBrowser/#/R-SSC-6782628 USP8 deubiquitinates STAM2:HGS IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6782820 https://reactome.org/PathwayBrowser/#/R-SSC-6782820 USP17 deubiquitinates SUDS3 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6783177 https://reactome.org/PathwayBrowser/#/R-SSC-6783177 USP21 deubiquitinates GATA3,IL33 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6784402 https://reactome.org/PathwayBrowser/#/R-SSC-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6784959 https://reactome.org/PathwayBrowser/#/R-SSC-6784959 BPHL hydrolyses VACV to ACV IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6786190 https://reactome.org/PathwayBrowser/#/R-SSC-6786190 CMBL hydrolyses OM to OLMS IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6786421 https://reactome.org/PathwayBrowser/#/R-SSC-6786421 CHIA hydrolyses chitin IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6786650 https://reactome.org/PathwayBrowser/#/R-SSC-6786650 DDHD1,2 hydrolyse PA IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6786652 https://reactome.org/PathwayBrowser/#/R-SSC-6786652 CHIT1 hydrolyses CHIT to 3xADGP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6787632 https://reactome.org/PathwayBrowser/#/R-SSC-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6788295 https://reactome.org/PathwayBrowser/#/R-SSC-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6788912 https://reactome.org/PathwayBrowser/#/R-SSC-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Sus scrofa 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6789310 https://reactome.org/PathwayBrowser/#/R-SSC-6789310 LIPs hydrolyse TG to DAG and RCOOH IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6792445 https://reactome.org/PathwayBrowser/#/R-SSC-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6792863 https://reactome.org/PathwayBrowser/#/R-SSC-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6797627 https://reactome.org/PathwayBrowser/#/R-SSC-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6797630 https://reactome.org/PathwayBrowser/#/R-SSC-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6797653 https://reactome.org/PathwayBrowser/#/R-SSC-6797653 DMGDH:FAD oxidatively demethylates DMGLY to SARC IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6797913 https://reactome.org/PathwayBrowser/#/R-SSC-6797913 SARDH:FAD oxidatively demethylates SARC to Gly IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6797955 https://reactome.org/PathwayBrowser/#/R-SSC-6797955 ALDH7A1 oxidises BETALD to BET IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6799545 https://reactome.org/PathwayBrowser/#/R-SSC-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-6799581 https://reactome.org/PathwayBrowser/#/R-SSC-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6799604 https://reactome.org/PathwayBrowser/#/R-SSC-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6799695 https://reactome.org/PathwayBrowser/#/R-SSC-6799695 GPX5,6 reduce H2O2 to H2O IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6799977 https://reactome.org/PathwayBrowser/#/R-SSC-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6800198 https://reactome.org/PathwayBrowser/#/R-SSC-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6800200 https://reactome.org/PathwayBrowser/#/R-SSC-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6800299 https://reactome.org/PathwayBrowser/#/R-SSC-6800299 HGFAC cleaves pro-HGF to form HGF dimer IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6801462 https://reactome.org/PathwayBrowser/#/R-SSC-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6803545 https://reactome.org/PathwayBrowser/#/R-SSC-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-6803753 https://reactome.org/PathwayBrowser/#/R-SSC-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6803789 https://reactome.org/PathwayBrowser/#/R-SSC-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6805650 https://reactome.org/PathwayBrowser/#/R-SSC-6805650 MTA2-NuRD complex deacetylates TP53 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6807027 https://reactome.org/PathwayBrowser/#/R-SSC-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6807118 https://reactome.org/PathwayBrowser/#/R-SSC-6807118 USP7 deubiquitinates monoubiquitinated PTEN IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6807206 https://reactome.org/PathwayBrowser/#/R-SSC-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-6807214 https://reactome.org/PathwayBrowser/#/R-SSC-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-6809263 https://reactome.org/PathwayBrowser/#/R-SSC-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6809320 https://reactome.org/PathwayBrowser/#/R-SSC-6809320 PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6809325 https://reactome.org/PathwayBrowser/#/R-SSC-6809325 PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6809720 https://reactome.org/PathwayBrowser/#/R-SSC-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6809777 https://reactome.org/PathwayBrowser/#/R-SSC-6809777 PI3P is dephosphorylated to PI by MTMR2:SBF1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6809778 https://reactome.org/PathwayBrowser/#/R-SSC-6809778 PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-6810076 https://reactome.org/PathwayBrowser/#/R-SSC-6810076 DDO oxidizes D-Asp to OA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-6810410 https://reactome.org/PathwayBrowser/#/R-SSC-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6810464 https://reactome.org/PathwayBrowser/#/R-SSC-6810464 NUDT14 hydrolyses UDP-Glc to G1P and UMP IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-6810472 https://reactome.org/PathwayBrowser/#/R-SSC-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6813720 https://reactome.org/PathwayBrowser/#/R-SSC-6813720 NCEH1 hydrolyzes cholesterol esters IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6813740 https://reactome.org/PathwayBrowser/#/R-SSC-6813740 GDE1 hydrolyzes GroPIns IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-6814254 https://reactome.org/PathwayBrowser/#/R-SSC-6814254 PNPLA6 hydrolyzes LysoPtdCho IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-6814797 https://reactome.org/PathwayBrowser/#/R-SSC-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-69199 https://reactome.org/PathwayBrowser/#/R-SSC-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70262 https://reactome.org/PathwayBrowser/#/R-SSC-70262 PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70479 https://reactome.org/PathwayBrowser/#/R-SSC-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70494 https://reactome.org/PathwayBrowser/#/R-SSC-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70569 https://reactome.org/PathwayBrowser/#/R-SSC-70569 arginine + H2O => ornithine + urea [ARG1] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70609 https://reactome.org/PathwayBrowser/#/R-SSC-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70785 https://reactome.org/PathwayBrowser/#/R-SSC-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70870 https://reactome.org/PathwayBrowser/#/R-SSC-70870 ECHS1 hydrates methacrylyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70903 https://reactome.org/PathwayBrowser/#/R-SSC-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-70906 https://reactome.org/PathwayBrowser/#/R-SSC-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-70982 https://reactome.org/PathwayBrowser/#/R-SSC-70982 FH tetramer hydrates fumarate to L-malate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71146 https://reactome.org/PathwayBrowser/#/R-SSC-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71660 https://reactome.org/PathwayBrowser/#/R-SSC-71660 Enolase dimers dehydrates 2PG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71676 https://reactome.org/PathwayBrowser/#/R-SSC-71676 GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-71732 https://reactome.org/PathwayBrowser/#/R-SSC-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-71825 https://reactome.org/PathwayBrowser/#/R-SSC-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73608 https://reactome.org/PathwayBrowser/#/R-SSC-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73797 https://reactome.org/PathwayBrowser/#/R-SSC-73797 FAICAR => IMP + H2O IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-73815 https://reactome.org/PathwayBrowser/#/R-SSC-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74059 https://reactome.org/PathwayBrowser/#/R-SSC-74059 PDE6 hydrolyses cGMP to GMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74241 https://reactome.org/PathwayBrowser/#/R-SSC-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74247 https://reactome.org/PathwayBrowser/#/R-SSC-74247 XDH oxidizes hypoxanthine to form xanthine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74248 https://reactome.org/PathwayBrowser/#/R-SSC-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74258 https://reactome.org/PathwayBrowser/#/R-SSC-74258 XDH oxidizes xanthine to form urate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74733 https://reactome.org/PathwayBrowser/#/R-SSC-74733 Insulin receptor de-phosphorylation IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-74948 https://reactome.org/PathwayBrowser/#/R-SSC-74948 PP2A dephosphorylates p-RHO to RHO IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-75899 https://reactome.org/PathwayBrowser/#/R-SSC-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-76031 https://reactome.org/PathwayBrowser/#/R-SSC-76031 2 H2O2 => O2 + 2 H2O IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76397 https://reactome.org/PathwayBrowser/#/R-SSC-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-76590 https://reactome.org/PathwayBrowser/#/R-SSC-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77256 https://reactome.org/PathwayBrowser/#/R-SSC-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77277 https://reactome.org/PathwayBrowser/#/R-SSC-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77301 https://reactome.org/PathwayBrowser/#/R-SSC-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77314 https://reactome.org/PathwayBrowser/#/R-SSC-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77325 https://reactome.org/PathwayBrowser/#/R-SSC-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77333 https://reactome.org/PathwayBrowser/#/R-SSC-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-77344 https://reactome.org/PathwayBrowser/#/R-SSC-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-77614 https://reactome.org/PathwayBrowser/#/R-SSC-77614 Deamination at C6 position of adenosine in Editosome (ADAR1) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-77615 https://reactome.org/PathwayBrowser/#/R-SSC-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-83677 https://reactome.org/PathwayBrowser/#/R-SSC-83677 C4 deamination of cytidine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-870437 https://reactome.org/PathwayBrowser/#/R-SSC-870437 USP9X (FAM) deubiquitinates SMAD4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8848053 https://reactome.org/PathwayBrowser/#/R-SSC-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8848215 https://reactome.org/PathwayBrowser/#/R-SSC-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8848338 https://reactome.org/PathwayBrowser/#/R-SSC-8848338 PNPLA4 hydrolyzes TAG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8848355 https://reactome.org/PathwayBrowser/#/R-SSC-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8848484 https://reactome.org/PathwayBrowser/#/R-SSC-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8849435 https://reactome.org/PathwayBrowser/#/R-SSC-8849435 PTPN1 dephosphorylates PTK6 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8849857 https://reactome.org/PathwayBrowser/#/R-SSC-8849857 KLK5 cleaves and activates CELA2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8849969 https://reactome.org/PathwayBrowser/#/R-SSC-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8850594 https://reactome.org/PathwayBrowser/#/R-SSC-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8850831 https://reactome.org/PathwayBrowser/#/R-SSC-8850831 KLK5 cleaves and activates KLK8 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-2022884 H2O [Golgi lumen] R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-2022884 H2O [Golgi lumen] R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8852200 https://reactome.org/PathwayBrowser/#/R-SSC-8852200 Inactivation of LCK by PTPN22 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8853379 https://reactome.org/PathwayBrowser/#/R-SSC-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-8853686 https://reactome.org/PathwayBrowser/#/R-SSC-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8854173 https://reactome.org/PathwayBrowser/#/R-SSC-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8854255 https://reactome.org/PathwayBrowser/#/R-SSC-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8854329 https://reactome.org/PathwayBrowser/#/R-SSC-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8854604 https://reactome.org/PathwayBrowser/#/R-SSC-8854604 TBC1D16 accelerates GTP hydrolysis by RAB4A IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8854612 https://reactome.org/PathwayBrowser/#/R-SSC-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8855381 https://reactome.org/PathwayBrowser/#/R-SSC-8855381 PTPN22 dephosphorylates ZAP70 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8855490 https://reactome.org/PathwayBrowser/#/R-SSC-8855490 Lactoperoxidase (LPO) produces OSCN- IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8855825 https://reactome.org/PathwayBrowser/#/R-SSC-8855825 HTRA1 hydrolyzes ACAN (Aggrecan) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-8856951 https://reactome.org/PathwayBrowser/#/R-SSC-8856951 PP2A demethylation by PPME1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-8862184 https://reactome.org/PathwayBrowser/#/R-SSC-8862184 USP48 cleaves polyubiquitin IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8862320 https://reactome.org/PathwayBrowser/#/R-SSC-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8863804 https://reactome.org/PathwayBrowser/#/R-SSC-8863804 PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8864029 https://reactome.org/PathwayBrowser/#/R-SSC-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8864036 https://reactome.org/PathwayBrowser/#/R-SSC-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8864125 https://reactome.org/PathwayBrowser/#/R-SSC-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-8865667 https://reactome.org/PathwayBrowser/#/R-SSC-8865667 LIPA hydrolyses sterol esters to sterols and fatty acids IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8866405 https://reactome.org/PathwayBrowser/#/R-SSC-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8866542 https://reactome.org/PathwayBrowser/#/R-SSC-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8867047 https://reactome.org/PathwayBrowser/#/R-SSC-8867047 PTPN3 dephosphorylates EPS15 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-8867344 https://reactome.org/PathwayBrowser/#/R-SSC-8867344 OMA1 hydrolyses OPA1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8867658 https://reactome.org/PathwayBrowser/#/R-SSC-8867658 PTPN3 dephosphorylates MAPK12 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8868648 https://reactome.org/PathwayBrowser/#/R-SSC-8868648 SYNJ hydrolyze PI(4,5)P2 to PI(4)P IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8868658 https://reactome.org/PathwayBrowser/#/R-SSC-8868658 HSPA8-mediated ATP hydrolysis promotes vesicle uncoating IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8868661 https://reactome.org/PathwayBrowser/#/R-SSC-8868661 Dynamin-mediated GTP hydrolysis promotes vesicle scission IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8869206 https://reactome.org/PathwayBrowser/#/R-SSC-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8869425 https://reactome.org/PathwayBrowser/#/R-SSC-8869425 PLA1A hydrolyses PS to 2-acyl LPS IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8869456 https://reactome.org/PathwayBrowser/#/R-SSC-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8869506 https://reactome.org/PathwayBrowser/#/R-SSC-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8874435 https://reactome.org/PathwayBrowser/#/R-SSC-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8875443 https://reactome.org/PathwayBrowser/#/R-SSC-8875443 USP8 deubiquitinates LRIG1 IEA Sus scrofa 15377 R-ALL-5668574 H2O [melanosome lumen] R-SSC-8878581 https://reactome.org/PathwayBrowser/#/R-SSC-8878581 TYRP1 oxidises DHICA to IQCA IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-8878654 https://reactome.org/PathwayBrowser/#/R-SSC-8878654 ACP6 hydrolyses MYS-LPA IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8878787 https://reactome.org/PathwayBrowser/#/R-SSC-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8932633 https://reactome.org/PathwayBrowser/#/R-SSC-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8933328 https://reactome.org/PathwayBrowser/#/R-SSC-8933328 LYPLA2 hydrolyses PALM-C3,4-GAP43 IEA Sus scrofa 15377 R-ALL-1222475 H2O [phagocytic vesicle lumen] R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-893596 https://reactome.org/PathwayBrowser/#/R-SSC-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8937442 https://reactome.org/PathwayBrowser/#/R-SSC-8937442 CES3 hydrolyses CHEST to CHOL and LCFA(-) IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-8937767 https://reactome.org/PathwayBrowser/#/R-SSC-8937767 PTPN11 dephosphorylates RUNX1 IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8940074 https://reactome.org/PathwayBrowser/#/R-SSC-8940074 NT5E:Zn2+ hydrolyses NMN IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8940388 https://reactome.org/PathwayBrowser/#/R-SSC-8940388 GPLD1 hydrolyses GPI-anchors from proteins IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8943279 https://reactome.org/PathwayBrowser/#/R-SSC-8943279 GGT dimers hydrolyse GSH IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8952137 https://reactome.org/PathwayBrowser/#/R-SSC-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8952251 https://reactome.org/PathwayBrowser/#/R-SSC-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-8952903 https://reactome.org/PathwayBrowser/#/R-SSC-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8953339 https://reactome.org/PathwayBrowser/#/R-SSC-8953339 DNPH1 hydrolyses dGMP IEA Sus scrofa 15377 R-ALL-2022884 H2O [Golgi lumen] R-SSC-8953499 https://reactome.org/PathwayBrowser/#/R-SSC-8953499 IMPAD1 hydrolyses PAP to AMP IEA Sus scrofa 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SSC-8954398 https://reactome.org/PathwayBrowser/#/R-SSC-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8955794 https://reactome.org/PathwayBrowser/#/R-SSC-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-8955817 https://reactome.org/PathwayBrowser/#/R-SSC-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-8957389 https://reactome.org/PathwayBrowser/#/R-SSC-8957389 RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-8980228 https://reactome.org/PathwayBrowser/#/R-SSC-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8981637 https://reactome.org/PathwayBrowser/#/R-SSC-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-8985594 https://reactome.org/PathwayBrowser/#/R-SSC-8985594 MYO9B inactivates RHOA IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-9008822 https://reactome.org/PathwayBrowser/#/R-SSC-9008822 PPM1D dephosphorylates RUNX2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9013022 https://reactome.org/PathwayBrowser/#/R-SSC-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9013111 https://reactome.org/PathwayBrowser/#/R-SSC-9013111 RHOC GAPs stimulate RHOC GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9013144 https://reactome.org/PathwayBrowser/#/R-SSC-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9013161 https://reactome.org/PathwayBrowser/#/R-SSC-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9013437 https://reactome.org/PathwayBrowser/#/R-SSC-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9014295 https://reactome.org/PathwayBrowser/#/R-SSC-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9014434 https://reactome.org/PathwayBrowser/#/R-SSC-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9014641 https://reactome.org/PathwayBrowser/#/R-SSC-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9017488 https://reactome.org/PathwayBrowser/#/R-SSC-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018745 https://reactome.org/PathwayBrowser/#/R-SSC-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018806 https://reactome.org/PathwayBrowser/#/R-SSC-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018814 https://reactome.org/PathwayBrowser/#/R-SSC-9018814 RHOT1 hydrolyzes GTP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018826 https://reactome.org/PathwayBrowser/#/R-SSC-9018826 RHOT2 hydrolyzes GTP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018862 https://reactome.org/PathwayBrowser/#/R-SSC-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018868 https://reactome.org/PathwayBrowser/#/R-SSC-9018868 GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018877 https://reactome.org/PathwayBrowser/#/R-SSC-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9018895 https://reactome.org/PathwayBrowser/#/R-SSC-9018895 GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020252 https://reactome.org/PathwayBrowser/#/R-SSC-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020253 https://reactome.org/PathwayBrowser/#/R-SSC-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020257 https://reactome.org/PathwayBrowser/#/R-SSC-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020258 https://reactome.org/PathwayBrowser/#/R-SSC-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020270 https://reactome.org/PathwayBrowser/#/R-SSC-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020271 https://reactome.org/PathwayBrowser/#/R-SSC-9020271 GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9020273 https://reactome.org/PathwayBrowser/#/R-SSC-9020273 GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9024890 https://reactome.org/PathwayBrowser/#/R-SSC-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9024993 https://reactome.org/PathwayBrowser/#/R-SSC-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9026408 https://reactome.org/PathwayBrowser/#/R-SSC-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9033491 https://reactome.org/PathwayBrowser/#/R-SSC-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Sus scrofa 15377 R-ALL-141343 H2O [peroxisomal matrix] R-SSC-9033520 https://reactome.org/PathwayBrowser/#/R-SSC-9033520 TYSND1 cleaves TYSND1 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9036727 https://reactome.org/PathwayBrowser/#/R-SSC-9036727 GAA hydrolyzes lysosomal glycogen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-936802 https://reactome.org/PathwayBrowser/#/R-SSC-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-936883 https://reactome.org/PathwayBrowser/#/R-SSC-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-936897 https://reactome.org/PathwayBrowser/#/R-SSC-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-939763 https://reactome.org/PathwayBrowser/#/R-SSC-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-947531 https://reactome.org/PathwayBrowser/#/R-SSC-947531 Molybdenum ion transfer onto molybdopterin IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-947535 https://reactome.org/PathwayBrowser/#/R-SSC-947535 Cyclisation of GTP to precursor Z IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-947591 https://reactome.org/PathwayBrowser/#/R-SSC-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9624893 https://reactome.org/PathwayBrowser/#/R-SSC-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9629675 https://reactome.org/PathwayBrowser/#/R-SSC-9629675 PDE3A hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9638075 https://reactome.org/PathwayBrowser/#/R-SSC-9638075 HEXB cleaves the terminal GalNAc from DS IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9638076 https://reactome.org/PathwayBrowser/#/R-SSC-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9638078 https://reactome.org/PathwayBrowser/#/R-SSC-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9638120 https://reactome.org/PathwayBrowser/#/R-SSC-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9644869 https://reactome.org/PathwayBrowser/#/R-SSC-9644869 p-S54-PDE4B hydrolyses cAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9647994 https://reactome.org/PathwayBrowser/#/R-SSC-9647994 RAS proteins are depalmitoylated IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-965067 https://reactome.org/PathwayBrowser/#/R-SSC-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-965079 https://reactome.org/PathwayBrowser/#/R-SSC-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9653514 https://reactome.org/PathwayBrowser/#/R-SSC-9653514 USP17L2 deubiquitinates RCE1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9656891 https://reactome.org/PathwayBrowser/#/R-SSC-9656891 OPN1SW binds 11cRAL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9656893 https://reactome.org/PathwayBrowser/#/R-SSC-9656893 OPN1MW binds 11cRAL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9658445 https://reactome.org/PathwayBrowser/#/R-SSC-9658445 MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9659680 https://reactome.org/PathwayBrowser/#/R-SSC-9659680 ABCB1 transports xenobiotics out of the cell IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9661417 https://reactome.org/PathwayBrowser/#/R-SSC-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9667952 https://reactome.org/PathwayBrowser/#/R-SSC-9667952 ANKLE2 is deacetylated by SIRT2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9668419 https://reactome.org/PathwayBrowser/#/R-SSC-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-9673053 https://reactome.org/PathwayBrowser/#/R-SSC-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-9673054 https://reactome.org/PathwayBrowser/#/R-SSC-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9674127 https://reactome.org/PathwayBrowser/#/R-SSC-9674127 USP30 deubiquitinates ATM dimer:Ub-p-PEX5 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-9686524 https://reactome.org/PathwayBrowser/#/R-SSC-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9693282 https://reactome.org/PathwayBrowser/#/R-SSC-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9700200 https://reactome.org/PathwayBrowser/#/R-SSC-9700200 PTPRZ dephosphorylates ligand-bound ALK dimers IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9701507 https://reactome.org/PathwayBrowser/#/R-SSC-9701507 PTPN6 dephosphorylates JAK3 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-9701565 https://reactome.org/PathwayBrowser/#/R-SSC-9701565 HDACs deacetylate p-STAT3 dimers IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9705507 https://reactome.org/PathwayBrowser/#/R-SSC-9705507 PDE3B hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9708261 https://reactome.org/PathwayBrowser/#/R-SSC-9708261 PDE4A hydrolyses cAMP to AMP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-9709360 https://reactome.org/PathwayBrowser/#/R-SSC-9709360 H2O2 reduces MetHb IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9727567 https://reactome.org/PathwayBrowser/#/R-SSC-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9749986 https://reactome.org/PathwayBrowser/#/R-SSC-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9750016 https://reactome.org/PathwayBrowser/#/R-SSC-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9750546 https://reactome.org/PathwayBrowser/#/R-SSC-9750546 ABCC4 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9750555 https://reactome.org/PathwayBrowser/#/R-SSC-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9750617 https://reactome.org/PathwayBrowser/#/R-SSC-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9750656 https://reactome.org/PathwayBrowser/#/R-SSC-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9750942 https://reactome.org/PathwayBrowser/#/R-SSC-9750942 USP14 deubiquitinates NLRC5 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753278 https://reactome.org/PathwayBrowser/#/R-SSC-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753280 https://reactome.org/PathwayBrowser/#/R-SSC-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753283 https://reactome.org/PathwayBrowser/#/R-SSC-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753284 https://reactome.org/PathwayBrowser/#/R-SSC-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753632 https://reactome.org/PathwayBrowser/#/R-SSC-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753634 https://reactome.org/PathwayBrowser/#/R-SSC-9753634 GGT dimers hydrolyse APAP-SG IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9753944 https://reactome.org/PathwayBrowser/#/R-SSC-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9754964 https://reactome.org/PathwayBrowser/#/R-SSC-9754964 ADA deamidates RBV IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9755030 https://reactome.org/PathwayBrowser/#/R-SSC-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9755078 https://reactome.org/PathwayBrowser/#/R-SSC-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-975593 https://reactome.org/PathwayBrowser/#/R-SSC-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-SSC-975594 https://reactome.org/PathwayBrowser/#/R-SSC-975594 PLB1 hydrolyses RPALM to atROL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9759206 https://reactome.org/PathwayBrowser/#/R-SSC-9759206 ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9759454 https://reactome.org/PathwayBrowser/#/R-SSC-9759454 ABCB1 transports PREDN,PREDL out of kidney cells IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9759461 https://reactome.org/PathwayBrowser/#/R-SSC-9759461 ABCB1 transports PREDN,PREDL out of hepatic cells IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-977324 https://reactome.org/PathwayBrowser/#/R-SSC-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9794120 https://reactome.org/PathwayBrowser/#/R-SSC-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9794572 https://reactome.org/PathwayBrowser/#/R-SSC-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-9825772 https://reactome.org/PathwayBrowser/#/R-SSC-9825772 SIRT1 deacetylates HINT1 dimer IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-983144 https://reactome.org/PathwayBrowser/#/R-SSC-983144 Transport of Antigen peptide in to ER IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-983422 https://reactome.org/PathwayBrowser/#/R-SSC-983422 Disassembly of COPII coated vesicle IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9837419 https://reactome.org/PathwayBrowser/#/R-SSC-9837419 PANK4 hydrolyzes PPANT to pantetheine IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9838004 https://reactome.org/PathwayBrowser/#/R-SSC-9838004 LONP1 degrades mitochondrial inner membrane proteins IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9838081 https://reactome.org/PathwayBrowser/#/R-SSC-9838081 LONP1 degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9838289 https://reactome.org/PathwayBrowser/#/R-SSC-9838289 CLPXP degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9839059 https://reactome.org/PathwayBrowser/#/R-SSC-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Sus scrofa 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SSC-9839072 https://reactome.org/PathwayBrowser/#/R-SSC-9839072 HTRA2 degrades APP (Amyloid-beta precursor protein) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9839105 https://reactome.org/PathwayBrowser/#/R-SSC-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Sus scrofa 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SSC-9839110 https://reactome.org/PathwayBrowser/#/R-SSC-9839110 HTRA2 degrades NDUFA13 (GRIM-19) IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9839113 https://reactome.org/PathwayBrowser/#/R-SSC-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Sus scrofa 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-SSC-9840408 https://reactome.org/PathwayBrowser/#/R-SSC-9840408 OMA1 cleaves DELE1 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9840795 https://reactome.org/PathwayBrowser/#/R-SSC-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9840833 https://reactome.org/PathwayBrowser/#/R-SSC-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9840884 https://reactome.org/PathwayBrowser/#/R-SSC-9840884 bHEXA,bHEXS hydrolyze GM2A:SM2 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9840949 https://reactome.org/PathwayBrowser/#/R-SSC-9840949 ARSA removes sulfate from SM3 IEA Sus scrofa 15377 R-ALL-1605715 H2O [lysosomal lumen] R-SSC-9841189 https://reactome.org/PathwayBrowser/#/R-SSC-9841189 GLA hydrolyzes PSAP(195-273):Gal2Cer:PE IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9841847 https://reactome.org/PathwayBrowser/#/R-SSC-9841847 SIRT3 deacetylates Ac-K272,K290-FOXO3 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9853385 https://reactome.org/PathwayBrowser/#/R-SSC-9853385 PPP1CC dephosphorylates PLK1 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9861626 https://reactome.org/PathwayBrowser/#/R-SSC-9861626 SIRT4 cleaves lipoyl from DLAT IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9861725 https://reactome.org/PathwayBrowser/#/R-SSC-9861725 PGAM5 dodecamer dephosphorylates p-S336-ME1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9865167 https://reactome.org/PathwayBrowser/#/R-SSC-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9865226 https://reactome.org/PathwayBrowser/#/R-SSC-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9912636 https://reactome.org/PathwayBrowser/#/R-SSC-9912636 Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9912655 https://reactome.org/PathwayBrowser/#/R-SSC-9912655 Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9912747 https://reactome.org/PathwayBrowser/#/R-SSC-9912747 Proteasomal clevage of exogenous antigen (immunoproteasome catalyst) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9912751 https://reactome.org/PathwayBrowser/#/R-SSC-9912751 Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9915968 https://reactome.org/PathwayBrowser/#/R-SSC-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9915971 https://reactome.org/PathwayBrowser/#/R-SSC-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9915986 https://reactome.org/PathwayBrowser/#/R-SSC-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9915992 https://reactome.org/PathwayBrowser/#/R-SSC-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Sus scrofa 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-SSC-9915993 https://reactome.org/PathwayBrowser/#/R-SSC-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9915994 https://reactome.org/PathwayBrowser/#/R-SSC-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9915997 https://reactome.org/PathwayBrowser/#/R-SSC-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-9916401 https://reactome.org/PathwayBrowser/#/R-SSC-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Sus scrofa 15377 R-ALL-113521 H2O [mitochondrial matrix] R-SSC-9929439 https://reactome.org/PathwayBrowser/#/R-SSC-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-997309 https://reactome.org/PathwayBrowser/#/R-SSC-997309 Dephosphorylation of STAT1 by SHP2 IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-997311 https://reactome.org/PathwayBrowser/#/R-SSC-997311 Dephosphorylation of TYK2 by PTP1B IEA Sus scrofa 15377 R-ALL-29356 H2O [cytosol] R-SSC-997314 https://reactome.org/PathwayBrowser/#/R-SSC-997314 Dephosphorylation of JAK1 by SHP1 IEA Sus scrofa 15377 R-ALL-113518 H2O [nucleoplasm] R-SSC-997326 https://reactome.org/PathwayBrowser/#/R-SSC-997326 Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP IEA Sus scrofa 15377 R-ALL-109276 H2O [extracellular region] R-XTR-109278 https://reactome.org/PathwayBrowser/#/R-XTR-109278 NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-109291 https://reactome.org/PathwayBrowser/#/R-XTR-109291 CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109380 https://reactome.org/PathwayBrowser/#/R-XTR-109380 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109387 https://reactome.org/PathwayBrowser/#/R-XTR-109387 (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109415 https://reactome.org/PathwayBrowser/#/R-XTR-109415 AMP + H2O => adenosine + orthophosphate [NT5C1B] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109449 https://reactome.org/PathwayBrowser/#/R-XTR-109449 (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109470 https://reactome.org/PathwayBrowser/#/R-XTR-109470 (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-109480 https://reactome.org/PathwayBrowser/#/R-XTR-109480 TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-109514 https://reactome.org/PathwayBrowser/#/R-XTR-109514 TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-111742 https://reactome.org/PathwayBrowser/#/R-XTR-111742 RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-111879 https://reactome.org/PathwayBrowser/#/R-XTR-111879 PIP2 hydrolysis IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-111955 https://reactome.org/PathwayBrowser/#/R-XTR-111955 cAMP hydrolysis by Cam-PDE 1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-111962 https://reactome.org/PathwayBrowser/#/R-XTR-111962 PDE4A,C,D hydrolyse cAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-112037 https://reactome.org/PathwayBrowser/#/R-XTR-112037 Inactivation of PLC beta IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1183128 https://reactome.org/PathwayBrowser/#/R-XTR-1183128 PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1237129 https://reactome.org/PathwayBrowser/#/R-XTR-1237129 Acireductone is created IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1247910 https://reactome.org/PathwayBrowser/#/R-XTR-1247910 CNDP2:2Mn2+ dimer hydrolyses CysGly IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1247935 https://reactome.org/PathwayBrowser/#/R-XTR-1247935 OPLAH hydrolyses OPRO to L-Glu IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-1363274 https://reactome.org/PathwayBrowser/#/R-XTR-1363274 Dephosphorylation of p107 (RBL1) by PP2A IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-1363276 https://reactome.org/PathwayBrowser/#/R-XTR-1363276 Dephosphorylation of p130 (RBL2) by PP2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1369065 https://reactome.org/PathwayBrowser/#/R-XTR-1369065 ABCB6 transports porphyrin from cytosol to mitchondrial matrix IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-139906 https://reactome.org/PathwayBrowser/#/R-XTR-139906 Activation of BAD by calcineurin IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-140359 https://reactome.org/PathwayBrowser/#/R-XTR-140359 PGG2 is reduced to PGH2 by PTGS1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-141200 https://reactome.org/PathwayBrowser/#/R-XTR-141200 MAOB:FAD oxidatively deaminates of PEA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-141202 https://reactome.org/PathwayBrowser/#/R-XTR-141202 MAOB:FAD oxidatively deaminates TYR IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-141341 https://reactome.org/PathwayBrowser/#/R-XTR-141341 SMOX-3 oxidises SPN to SPM IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1454916 https://reactome.org/PathwayBrowser/#/R-XTR-1454916 The ABCC family mediates organic anion transport IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1454928 https://reactome.org/PathwayBrowser/#/R-XTR-1454928 ABCG4 may mediate cholesterol efflux IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1467466 https://reactome.org/PathwayBrowser/#/R-XTR-1467466 ABCA4 mediates atRAL transport IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1474146 https://reactome.org/PathwayBrowser/#/R-XTR-1474146 GCH1 reduces GTP to dihydroneopterin triphosphate IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482543 https://reactome.org/PathwayBrowser/#/R-XTR-1482543 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482604 https://reactome.org/PathwayBrowser/#/R-XTR-1482604 PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482612 https://reactome.org/PathwayBrowser/#/R-XTR-1482612 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482656 https://reactome.org/PathwayBrowser/#/R-XTR-1482656 PA is hydrolysed to 1-acyl LPA by PLA2[1] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482679 https://reactome.org/PathwayBrowser/#/R-XTR-1482679 PA is hydrolysed to 1-acyl LPA by PLA2G2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482685 https://reactome.org/PathwayBrowser/#/R-XTR-1482685 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1482745 https://reactome.org/PathwayBrowser/#/R-XTR-1482745 PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1482759 https://reactome.org/PathwayBrowser/#/R-XTR-1482759 MLCL is hydrolyzed to DLCL by PLA2G4A (IM) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482771 https://reactome.org/PathwayBrowser/#/R-XTR-1482771 PS is hydrolyzed to 1-acyl LPS by PLA2[9] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482776 https://reactome.org/PathwayBrowser/#/R-XTR-1482776 PS is hydrolyzed to 1-acyl LPS by PLA2G2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482777 https://reactome.org/PathwayBrowser/#/R-XTR-1482777 TAG is hydrolyzed to DAG by PNPLA2/3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482811 https://reactome.org/PathwayBrowser/#/R-XTR-1482811 DAG is hydrolyzed to 2-MAG by PNPLA2/3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482816 https://reactome.org/PathwayBrowser/#/R-XTR-1482816 PC is hydrolyzed to 1-acyl LPC by PLA2[6] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482825 https://reactome.org/PathwayBrowser/#/R-XTR-1482825 PI is hydrolyzed to 1-acyl LPI by PLA2[11] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482828 https://reactome.org/PathwayBrowser/#/R-XTR-1482828 PE is hydrolyzed to 2-acyl LPE by PLA2[4] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1482847 https://reactome.org/PathwayBrowser/#/R-XTR-1482847 PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482856 https://reactome.org/PathwayBrowser/#/R-XTR-1482856 PC is hydrolyzed to 1-acyl LPC by PLA2[5] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482862 https://reactome.org/PathwayBrowser/#/R-XTR-1482862 PC is hydrolysed to 2-acyl LPC by PLA2[7] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482868 https://reactome.org/PathwayBrowser/#/R-XTR-1482868 PI is hydrolyzed to 1-acyl LPI by PLA2[12] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482884 https://reactome.org/PathwayBrowser/#/R-XTR-1482884 PE is hydrolyzed to 1-acyl LPE by PLA2[2] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482887 https://reactome.org/PathwayBrowser/#/R-XTR-1482887 PE is hydrolyzed to 1-acyl LPE by PLA2[3] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482897 https://reactome.org/PathwayBrowser/#/R-XTR-1482897 PS is hydrolyzed to 2-acyl LPS by PLA2[10] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482900 https://reactome.org/PathwayBrowser/#/R-XTR-1482900 PG is hydrolyzed to 1-acyl LPG by PLA2[1] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482907 https://reactome.org/PathwayBrowser/#/R-XTR-1482907 PG is hydrolyzed to 1-acyl LPG by PLA2G2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1482920 https://reactome.org/PathwayBrowser/#/R-XTR-1482920 PG is hydrolyzed to 2-acyl LPG by PLA2[14] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1483096 https://reactome.org/PathwayBrowser/#/R-XTR-1483096 PETA is dephosphorylated to ETA by PHOSPHO1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1483159 https://reactome.org/PathwayBrowser/#/R-XTR-1483159 PCho is dephosphorylated to Cho by PHOSPHO1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1483182 https://reactome.org/PathwayBrowser/#/R-XTR-1483182 PC is hydrolyzed to PA and choline by PLD1/2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1483203 https://reactome.org/PathwayBrowser/#/R-XTR-1483203 PA is dephosphorylated to DAG by LPIN IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-159425 https://reactome.org/PathwayBrowser/#/R-XTR-159425 Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159752 https://reactome.org/PathwayBrowser/#/R-XTR-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159761 https://reactome.org/PathwayBrowser/#/R-XTR-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159795 https://reactome.org/PathwayBrowser/#/R-XTR-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159803 https://reactome.org/PathwayBrowser/#/R-XTR-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159819 https://reactome.org/PathwayBrowser/#/R-XTR-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-159826 https://reactome.org/PathwayBrowser/#/R-XTR-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602368 https://reactome.org/PathwayBrowser/#/R-XTR-1602368 PG is hydrolyzed to 1-acyl LPG by PLA2[16] IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602374 https://reactome.org/PathwayBrowser/#/R-XTR-1602374 PS is hydrolyzed to 1-acyl LPS by PLA2[15] IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602377 https://reactome.org/PathwayBrowser/#/R-XTR-1602377 PI is hydrolyzed to 1-acyl LPI by PLA2[15] IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602398 https://reactome.org/PathwayBrowser/#/R-XTR-1602398 PE is hydrolyzed to 1-acyl LPE by PLA2[16] IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602417 https://reactome.org/PathwayBrowser/#/R-XTR-1602417 PC is hydrolyzed to 1-acyl LPC by PLA2[16] IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-1602446 https://reactome.org/PathwayBrowser/#/R-XTR-1602446 PA is hydrolyzed to 1-acyl LPA by PLA2[15] IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1605624 https://reactome.org/PathwayBrowser/#/R-XTR-1605624 Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1605723 https://reactome.org/PathwayBrowser/#/R-XTR-1605723 NEU2 cleaves GM3 to form LacCer (cytosol) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1605768 https://reactome.org/PathwayBrowser/#/R-XTR-1605768 NEU3 cleaves GM3 to form LacCer (plasma membrane) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1606583 https://reactome.org/PathwayBrowser/#/R-XTR-1606583 ASAH2 hydrolyzes ceramide (plasma membrane) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-1606839 https://reactome.org/PathwayBrowser/#/R-XTR-1606839 ARSC hydrolyzes steroid sulfates IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1614544 https://reactome.org/PathwayBrowser/#/R-XTR-1614544 Sulfite is oxidized to sulfate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1614583 https://reactome.org/PathwayBrowser/#/R-XTR-1614583 PXLP-K212-CTH cleaves L-Cystathionine IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to pyruvate and H2S IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-162425 https://reactome.org/PathwayBrowser/#/R-XTR-162425 p-S295-PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-162857 https://reactome.org/PathwayBrowser/#/R-XTR-162857 N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1630304 https://reactome.org/PathwayBrowser/#/R-XTR-1630304 GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1630306 https://reactome.org/PathwayBrowser/#/R-XTR-1630306 GLB1 hydrolyses a glycosaminoglycan IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1638032 https://reactome.org/PathwayBrowser/#/R-XTR-1638032 N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-163820 https://reactome.org/PathwayBrowser/#/R-XTR-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1638821 https://reactome.org/PathwayBrowser/#/R-XTR-1638821 PP2A-B56 dephosphorylates centromeric cohesin IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1667005 https://reactome.org/PathwayBrowser/#/R-XTR-1667005 Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675795 https://reactome.org/PathwayBrowser/#/R-XTR-1675795 PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675824 https://reactome.org/PathwayBrowser/#/R-XTR-1675824 PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675836 https://reactome.org/PathwayBrowser/#/R-XTR-1675836 PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675949 https://reactome.org/PathwayBrowser/#/R-XTR-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675988 https://reactome.org/PathwayBrowser/#/R-XTR-1675988 PI4P is dephosphorylated to PI by SYNJ at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1675994 https://reactome.org/PathwayBrowser/#/R-XTR-1675994 PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676065 https://reactome.org/PathwayBrowser/#/R-XTR-1676065 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676105 https://reactome.org/PathwayBrowser/#/R-XTR-1676105 PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676141 https://reactome.org/PathwayBrowser/#/R-XTR-1676141 PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676149 https://reactome.org/PathwayBrowser/#/R-XTR-1676149 PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676162 https://reactome.org/PathwayBrowser/#/R-XTR-1676162 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676164 https://reactome.org/PathwayBrowser/#/R-XTR-1676164 PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676177 https://reactome.org/PathwayBrowser/#/R-XTR-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676203 https://reactome.org/PathwayBrowser/#/R-XTR-1676203 PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1676204 https://reactome.org/PathwayBrowser/#/R-XTR-1676204 PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1678650 https://reactome.org/PathwayBrowser/#/R-XTR-1678650 IDS hydrolyses Heparan sulfate chain(5) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1678708 https://reactome.org/PathwayBrowser/#/R-XTR-1678708 SGSH hydrolyses Heparan sulfate chain(2) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1678716 https://reactome.org/PathwayBrowser/#/R-XTR-1678716 IDUA hydrolyses Heparan sulfate chain(1) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1678854 https://reactome.org/PathwayBrowser/#/R-XTR-1678854 GUSB tetramer hydrolyses CS/HS precursor IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-170153 https://reactome.org/PathwayBrowser/#/R-XTR-170153 Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-170158 https://reactome.org/PathwayBrowser/#/R-XTR-170158 CDC25A dephosphorylates CCNA:CDK1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-170161 https://reactome.org/PathwayBrowser/#/R-XTR-170161 Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-173739 https://reactome.org/PathwayBrowser/#/R-XTR-173739 Spontaneous hydrolysis of C3 thioester IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-174110 https://reactome.org/PathwayBrowser/#/R-XTR-174110 Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-174124 https://reactome.org/PathwayBrowser/#/R-XTR-174124 Dephosphorylation of phospho-Cdh1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-174391 https://reactome.org/PathwayBrowser/#/R-XTR-174391 MAT1A multimers transfer Ado from ATP to L-Met IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-174401 https://reactome.org/PathwayBrowser/#/R-XTR-174401 AHCY:NAD+ tetramer hydrolyses AdoHcy IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-174439 https://reactome.org/PathwayBrowser/#/R-XTR-174439 Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-176606 https://reactome.org/PathwayBrowser/#/R-XTR-176606 Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-177924 https://reactome.org/PathwayBrowser/#/R-XTR-177924 Dephosphorylation of Gab1 by SHP2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-177926 https://reactome.org/PathwayBrowser/#/R-XTR-177926 Dephosphorylation of PAG by SHP2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-177935 https://reactome.org/PathwayBrowser/#/R-XTR-177935 SHP2 dephosphorylates Tyr 992 on EGFR IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1793182 https://reactome.org/PathwayBrowser/#/R-XTR-1793182 IDS hydrolyses dermatan sulfate (Chebi:63517 chain) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1793186 https://reactome.org/PathwayBrowser/#/R-XTR-1793186 IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-1793209 https://reactome.org/PathwayBrowser/#/R-XTR-1793209 HYAL1 hydrolyses Chondroitin chains IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855154 https://reactome.org/PathwayBrowser/#/R-XTR-1855154 I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855159 https://reactome.org/PathwayBrowser/#/R-XTR-1855159 I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-1855163 https://reactome.org/PathwayBrowser/#/R-XTR-1855163 I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855165 https://reactome.org/PathwayBrowser/#/R-XTR-1855165 (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855166 https://reactome.org/PathwayBrowser/#/R-XTR-1855166 PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855171 https://reactome.org/PathwayBrowser/#/R-XTR-1855171 I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855174 https://reactome.org/PathwayBrowser/#/R-XTR-1855174 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855177 https://reactome.org/PathwayBrowser/#/R-XTR-1855177 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855180 https://reactome.org/PathwayBrowser/#/R-XTR-1855180 I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855198 https://reactome.org/PathwayBrowser/#/R-XTR-1855198 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-1855200 https://reactome.org/PathwayBrowser/#/R-XTR-1855200 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855202 https://reactome.org/PathwayBrowser/#/R-XTR-1855202 I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855205 https://reactome.org/PathwayBrowser/#/R-XTR-1855205 I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855210 https://reactome.org/PathwayBrowser/#/R-XTR-1855210 I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855211 https://reactome.org/PathwayBrowser/#/R-XTR-1855211 I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855213 https://reactome.org/PathwayBrowser/#/R-XTR-1855213 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855214 https://reactome.org/PathwayBrowser/#/R-XTR-1855214 PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855218 https://reactome.org/PathwayBrowser/#/R-XTR-1855218 I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855219 https://reactome.org/PathwayBrowser/#/R-XTR-1855219 I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855221 https://reactome.org/PathwayBrowser/#/R-XTR-1855221 PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-1855222 https://reactome.org/PathwayBrowser/#/R-XTR-1855222 I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-1855225 https://reactome.org/PathwayBrowser/#/R-XTR-1855225 IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-188979 https://reactome.org/PathwayBrowser/#/R-XTR-188979 Digestion of linear starch (amylose) by extracellular amylase IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-189062 https://reactome.org/PathwayBrowser/#/R-XTR-189062 lactose + H2O => D-glucose + D-galactose IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-189398 https://reactome.org/PathwayBrowser/#/R-XTR-189398 HMOX1 dimer, HMOX2 cleave heme IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-189406 https://reactome.org/PathwayBrowser/#/R-XTR-189406 4 PBGs bind to form HMB IEA Xenopus tropicalis 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-189488 https://reactome.org/PathwayBrowser/#/R-XTR-189488 UROS transforms HMB to URO3 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-191114 https://reactome.org/PathwayBrowser/#/R-XTR-191114 Digestion of branched starch (amylopectin) by extracellular amylase IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-192417 https://reactome.org/PathwayBrowser/#/R-XTR-192417 Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-192422 https://reactome.org/PathwayBrowser/#/R-XTR-192422 Digestion of triacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-192425 https://reactome.org/PathwayBrowser/#/R-XTR-192425 Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-192430 https://reactome.org/PathwayBrowser/#/R-XTR-192430 Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-192434 https://reactome.org/PathwayBrowser/#/R-XTR-192434 Digestion of diacylglycerols by extracellular PTL:colipase IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-193385 https://reactome.org/PathwayBrowser/#/R-XTR-193385 Hydrolysis of choloyl-CoA to cholate and CoASH IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193711 https://reactome.org/PathwayBrowser/#/R-XTR-193711 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193727 https://reactome.org/PathwayBrowser/#/R-XTR-193727 TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193743 https://reactome.org/PathwayBrowser/#/R-XTR-193743 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193766 https://reactome.org/PathwayBrowser/#/R-XTR-193766 TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-199456 https://reactome.org/PathwayBrowser/#/R-XTR-199456 PTEN dephosphorylates PIP3 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2002466 https://reactome.org/PathwayBrowser/#/R-XTR-2002466 Formation of allysine by LOX IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-200661 https://reactome.org/PathwayBrowser/#/R-XTR-200661 MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-200740 https://reactome.org/PathwayBrowser/#/R-XTR-200740 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-201035 https://reactome.org/PathwayBrowser/#/R-XTR-201035 ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022368 https://reactome.org/PathwayBrowser/#/R-XTR-2022368 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-202237 https://reactome.org/PathwayBrowser/#/R-XTR-202237 Hydrolysis of PIP3 to PI(3,4)P2 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022378 https://reactome.org/PathwayBrowser/#/R-XTR-2022378 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022379 https://reactome.org/PathwayBrowser/#/R-XTR-2022379 ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022381 https://reactome.org/PathwayBrowser/#/R-XTR-2022381 Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022383 https://reactome.org/PathwayBrowser/#/R-XTR-2022383 Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022396 https://reactome.org/PathwayBrowser/#/R-XTR-2022396 MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022398 https://reactome.org/PathwayBrowser/#/R-XTR-2022398 ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022399 https://reactome.org/PathwayBrowser/#/R-XTR-2022399 ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022403 https://reactome.org/PathwayBrowser/#/R-XTR-2022403 Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022405 https://reactome.org/PathwayBrowser/#/R-XTR-2022405 ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022411 https://reactome.org/PathwayBrowser/#/R-XTR-2022411 Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2022412 https://reactome.org/PathwayBrowser/#/R-XTR-2022412 Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-ALL-2022884 H2O [Golgi lumen] R-XTR-2022887 https://reactome.org/PathwayBrowser/#/R-XTR-2022887 NDST1-4 N-deacetylates GlcNAc residues in heparan IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2023971 https://reactome.org/PathwayBrowser/#/R-XTR-2023971 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2023973 https://reactome.org/PathwayBrowser/#/R-XTR-2023973 (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-202407 https://reactome.org/PathwayBrowser/#/R-XTR-202407 PLC-gamma1 hydrolyses PIP2 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2028294 https://reactome.org/PathwayBrowser/#/R-XTR-2028294 Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2029468 https://reactome.org/PathwayBrowser/#/R-XTR-2029468 Conversion of PA into DAG by PAP-1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2029471 https://reactome.org/PathwayBrowser/#/R-XTR-2029471 Hydrolysis of PC to PA by PLD IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2029475 https://reactome.org/PathwayBrowser/#/R-XTR-2029475 Production of AA by iPLA2 upon FCGR activation IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-203797 https://reactome.org/PathwayBrowser/#/R-XTR-203797 ERKs are inactivated by dual-specific phosphatases (DUSPs) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046083 https://reactome.org/PathwayBrowser/#/R-XTR-2046083 Elongation of arachidonyl-CoA to docosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046088 https://reactome.org/PathwayBrowser/#/R-XTR-2046088 Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046089 https://reactome.org/PathwayBrowser/#/R-XTR-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046090 https://reactome.org/PathwayBrowser/#/R-XTR-2046090 Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046092 https://reactome.org/PathwayBrowser/#/R-XTR-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046094 https://reactome.org/PathwayBrowser/#/R-XTR-2046094 Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046095 https://reactome.org/PathwayBrowser/#/R-XTR-2046095 Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2046100 https://reactome.org/PathwayBrowser/#/R-XTR-2046100 Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2065355 https://reactome.org/PathwayBrowser/#/R-XTR-2065355 Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2065357 https://reactome.org/PathwayBrowser/#/R-XTR-2065357 Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-2066779 https://reactome.org/PathwayBrowser/#/R-XTR-2066779 Conversion of DHA-CoA to docosahexaenoic acid (DHA) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2090037 https://reactome.org/PathwayBrowser/#/R-XTR-2090037 IDUA hydrolyses Heparan sulfate chain(6) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2090043 https://reactome.org/PathwayBrowser/#/R-XTR-2090043 SGSH hydrolyses Heparan sulfate chain(7) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2090079 https://reactome.org/PathwayBrowser/#/R-XTR-2090079 GLB1 hydrolyses linker chain(2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 15377 R-ALL-351603 H2O [secretory granule lumen] R-XTR-209891 https://reactome.org/PathwayBrowser/#/R-XTR-209891 Dopamine is oxidised to noradrenaline IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2160492 https://reactome.org/PathwayBrowser/#/R-XTR-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2160874 https://reactome.org/PathwayBrowser/#/R-XTR-2160874 HYAL1 hydrolyses (HA)50 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161195 https://reactome.org/PathwayBrowser/#/R-XTR-2161195 abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2161961 https://reactome.org/PathwayBrowser/#/R-XTR-2161961 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-2162187 https://reactome.org/PathwayBrowser/#/R-XTR-2162187 COQ6 hydroxylates DHB IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2162226 https://reactome.org/PathwayBrowser/#/R-XTR-2162226 GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-2162227 https://reactome.org/PathwayBrowser/#/R-XTR-2162227 GUSB tetramer hydrolyses (HA)2 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2187401 https://reactome.org/PathwayBrowser/#/R-XTR-2187401 MTMR4 dephosphorylates SMAD2/3 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-2309773 https://reactome.org/PathwayBrowser/#/R-XTR-2309773 PGG2 is reduced to PGH2 by PTGS2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2393939 https://reactome.org/PathwayBrowser/#/R-XTR-2393939 Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-2393954 https://reactome.org/PathwayBrowser/#/R-XTR-2393954 Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2395340 https://reactome.org/PathwayBrowser/#/R-XTR-2395340 Formation of hydroxyallysine by LOX IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2408551 https://reactome.org/PathwayBrowser/#/R-XTR-2408551 SeMet is converted to AdoSeMet by MAT IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2465924 https://reactome.org/PathwayBrowser/#/R-XTR-2465924 OPN1LW binds 11cRAL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2466085 https://reactome.org/PathwayBrowser/#/R-XTR-2466085 at-retinyl is hydrolysed from R* to release atRAL IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2584246 https://reactome.org/PathwayBrowser/#/R-XTR-2584246 GNAT1-GTP hydrolyses its bound GTP to GDP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-266051 https://reactome.org/PathwayBrowser/#/R-XTR-266051 5S-HpETE is dehydrated to LTA4 by ALOX5 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-266070 https://reactome.org/PathwayBrowser/#/R-XTR-266070 LTC4 is exported from the cytosol by ABCC1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-266072 https://reactome.org/PathwayBrowser/#/R-XTR-266072 LTA4 is hydolysed to LTB4 by LTA4H IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-266082 https://reactome.org/PathwayBrowser/#/R-XTR-266082 ABCG1-mediated transport of intracellular cholesterol to the cell surface IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-2730847 https://reactome.org/PathwayBrowser/#/R-XTR-2730847 Hydrolysis of PIP2 by PLCG IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-2855047 https://reactome.org/PathwayBrowser/#/R-XTR-2855047 Hydrolysis of internal thioester in C4b IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-2995330 https://reactome.org/PathwayBrowser/#/R-XTR-2995330 COX10 transforms heme to heme O IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-2995334 https://reactome.org/PathwayBrowser/#/R-XTR-2995334 COX15 transforms heme O to heme A IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-3002811 https://reactome.org/PathwayBrowser/#/R-XTR-3002811 Myosin phosphatase dephosphorylates PLK1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-3095901 https://reactome.org/PathwayBrowser/#/R-XTR-3095901 ABCC1 transports cytosolic RCbl to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-3204311 https://reactome.org/PathwayBrowser/#/R-XTR-3204311 AOX1 oxidises PXL to PDXate IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-3322995 https://reactome.org/PathwayBrowser/#/R-XTR-3322995 PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-3341296 https://reactome.org/PathwayBrowser/#/R-XTR-3341296 GPX7,8 catalyze peroxidation of P4HB (PDI) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-3343700 https://reactome.org/PathwayBrowser/#/R-XTR-3343700 PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-350604 https://reactome.org/PathwayBrowser/#/R-XTR-350604 Agmatine + H2O <=> putrescine + urea IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-3697894 https://reactome.org/PathwayBrowser/#/R-XTR-3697894 PRDX5 reduces peroxynitrite to nitrite using TXN2 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-372519 https://reactome.org/PathwayBrowser/#/R-XTR-372519 AcCho is hydrolyzed to Cho and acetate by ACHE IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-382560 https://reactome.org/PathwayBrowser/#/R-XTR-382560 ABC7, mABC1 and mABC2 mediate heme transport IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-382575 https://reactome.org/PathwayBrowser/#/R-XTR-382575 ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-383190 https://reactome.org/PathwayBrowser/#/R-XTR-383190 HCO3- transport through ion channel IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-389821 https://reactome.org/PathwayBrowser/#/R-XTR-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-389862 https://reactome.org/PathwayBrowser/#/R-XTR-389862 Conversion of glyoxylate to oxalate IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-390393 https://reactome.org/PathwayBrowser/#/R-XTR-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4084976 https://reactome.org/PathwayBrowser/#/R-XTR-4084976 NANS converts ManNAc-6-P to Neu5Ac-9-P IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4084989 https://reactome.org/PathwayBrowser/#/R-XTR-4084989 NANP dephosphorylates Neu5Ac-9-P to Neu5Ac IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4084994 https://reactome.org/PathwayBrowser/#/R-XTR-4084994 NEU3 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-4084999 https://reactome.org/PathwayBrowser/#/R-XTR-4084999 NEU1 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4085021 https://reactome.org/PathwayBrowser/#/R-XTR-4085021 GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4085029 https://reactome.org/PathwayBrowser/#/R-XTR-4085029 NEU2 hydrolyzes Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4086392 https://reactome.org/PathwayBrowser/#/R-XTR-4086392 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-4088141 https://reactome.org/PathwayBrowser/#/R-XTR-4088141 PP2A-PPP2R2A dephosphorylates FOXM1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4093339 https://reactome.org/PathwayBrowser/#/R-XTR-4093339 p120-RasGAP activates GTP hydrolysis on RAS, inactivating it IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-416559 https://reactome.org/PathwayBrowser/#/R-XTR-416559 Inactivation of Rho-GTP by p190RhoGAP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-418553 https://reactome.org/PathwayBrowser/#/R-XTR-418553 cAMP degradation by Phosphodiesterases IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428205 https://reactome.org/PathwayBrowser/#/R-XTR-428205 ACER2 hydrolyzes ceramide (Golgi) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428231 https://reactome.org/PathwayBrowser/#/R-XTR-428231 ACER1 hydrolyzes ceramide (endoplasmic reticulum) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428262 https://reactome.org/PathwayBrowser/#/R-XTR-428262 ACER3 hydrolyzes phytoceramide IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428664 https://reactome.org/PathwayBrowser/#/R-XTR-428664 SGPP1,2 dephosphorylate sphingoid-1-phosphates IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-428696 https://reactome.org/PathwayBrowser/#/R-XTR-428696 PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-429860 https://reactome.org/PathwayBrowser/#/R-XTR-429860 DCP1-DCP2 complex decaps mRNA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-429955 https://reactome.org/PathwayBrowser/#/R-XTR-429955 CCR4-NOT complex deadenylates mRNA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-429961 https://reactome.org/PathwayBrowser/#/R-XTR-429961 DCPS scavenges the 7-methylguanosine cap of mRNA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-429992 https://reactome.org/PathwayBrowser/#/R-XTR-429992 PARN deadenylates mRNA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-430028 https://reactome.org/PathwayBrowser/#/R-XTR-430028 Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-432010 https://reactome.org/PathwayBrowser/#/R-XTR-432010 Aquaporin-1 passively transports water into cell IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-432010 https://reactome.org/PathwayBrowser/#/R-XTR-432010 Aquaporin-1 passively transports water into cell IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-432054 https://reactome.org/PathwayBrowser/#/R-XTR-432054 Aquaporin-1 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-432054 https://reactome.org/PathwayBrowser/#/R-XTR-432054 Aquaporin-1 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-432065 https://reactome.org/PathwayBrowser/#/R-XTR-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-432065 https://reactome.org/PathwayBrowser/#/R-XTR-432065 p-S256-Aquaporin-2 passively transports water into cell IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-432067 https://reactome.org/PathwayBrowser/#/R-XTR-432067 Aquaporin-4 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-432067 https://reactome.org/PathwayBrowser/#/R-XTR-432067 Aquaporin-4 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-4419948 https://reactome.org/PathwayBrowser/#/R-XTR-4419948 CTDNEP1:CNEP1R1 dephosphorylates LPIN IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-445714 https://reactome.org/PathwayBrowser/#/R-XTR-445714 Aquaporin-3 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-445714 https://reactome.org/PathwayBrowser/#/R-XTR-445714 Aquaporin-3 passively transports water out of cell IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-452036 https://reactome.org/PathwayBrowser/#/R-XTR-452036 arginine + H2O => ornithine + urea [ARG2] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-4641236 https://reactome.org/PathwayBrowser/#/R-XTR-4641236 USP8 deubiquitinates FZD to potentiate WNT signaling IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-507868 https://reactome.org/PathwayBrowser/#/R-XTR-507868 Aquaporins passively transport water into cells IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-507868 https://reactome.org/PathwayBrowser/#/R-XTR-507868 Aquaporins passively transport water into cells IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-507870 https://reactome.org/PathwayBrowser/#/R-XTR-507870 Aquaporins passively transport water out of cells IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-507870 https://reactome.org/PathwayBrowser/#/R-XTR-507870 Aquaporins passively transport water out of cells IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5221130 https://reactome.org/PathwayBrowser/#/R-XTR-5221130 LPIN catalyzes conversion of phosphatidic acid to diacylglycerol IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5251955 https://reactome.org/PathwayBrowser/#/R-XTR-5251955 HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5251959 https://reactome.org/PathwayBrowser/#/R-XTR-5251959 HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5251989 https://reactome.org/PathwayBrowser/#/R-XTR-5251989 ATP13A4,5 transport divalent ions from extracellular region to cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5362459 https://reactome.org/PathwayBrowser/#/R-XTR-5362459 VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5433074 https://reactome.org/PathwayBrowser/#/R-XTR-5433074 ACY1:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-548843 https://reactome.org/PathwayBrowser/#/R-XTR-548843 ACSL3,4 ligate CoA to AA to form AA-CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5603114 https://reactome.org/PathwayBrowser/#/R-XTR-5603114 MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5607735 https://reactome.org/PathwayBrowser/#/R-XTR-5607735 p-Y753,Y759-PLCG2 hydrolyses PIP2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5628905 https://reactome.org/PathwayBrowser/#/R-XTR-5628905 TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5631885 https://reactome.org/PathwayBrowser/#/R-XTR-5631885 PRDX1 overoxidizes IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5649705 https://reactome.org/PathwayBrowser/#/R-XTR-5649705 PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5651828 https://reactome.org/PathwayBrowser/#/R-XTR-5651828 PARG dePARylates PARP1,PARP2 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5653770 https://reactome.org/PathwayBrowser/#/R-XTR-5653770 USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA IEA Xenopus tropicalis 15377 R-ALL-5668574 H2O [melanosome lumen] R-XTR-5662692 https://reactome.org/PathwayBrowser/#/R-XTR-5662692 Dopa is oxidized to dopaquinone by TYR IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5675373 https://reactome.org/PathwayBrowser/#/R-XTR-5675373 Nuclear DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5675376 https://reactome.org/PathwayBrowser/#/R-XTR-5675376 Cytosolic DUSPs dephosphorylate MAPKs IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5675433 https://reactome.org/PathwayBrowser/#/R-XTR-5675433 PP5 dephosphorylates RAF1 S338 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5676637 https://reactome.org/PathwayBrowser/#/R-XTR-5676637 PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5678863 https://reactome.org/PathwayBrowser/#/R-XTR-5678863 CFTR transports Cl- from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5679041 https://reactome.org/PathwayBrowser/#/R-XTR-5679041 ABCC2 transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5683714 https://reactome.org/PathwayBrowser/#/R-XTR-5683714 ABCA3 transports PC, PG from ER membrane to lamellar body IEA Xenopus tropicalis 15377 R-ALL-5685882 H2O [multivesicular body lumen] R-XTR-5685902 https://reactome.org/PathwayBrowser/#/R-XTR-5685902 NAPSA, CTSH, PGA3-5 cleave pro-SFTPC IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5687758 https://reactome.org/PathwayBrowser/#/R-XTR-5687758 PPP4C:PPP4R2 dephosphorylates RPA2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5688797 https://reactome.org/PathwayBrowser/#/R-XTR-5688797 ATXN3 family cleave Ub chains IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5689973 https://reactome.org/PathwayBrowser/#/R-XTR-5689973 USP10,USP24,USP42 deubiquitinate TP53 IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690043 https://reactome.org/PathwayBrowser/#/R-XTR-5690043 Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5690066 https://reactome.org/PathwayBrowser/#/R-XTR-5690066 ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5690080 https://reactome.org/PathwayBrowser/#/R-XTR-5690080 USP3,SAGA deubiquitinate Histone H2A,H2B IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5690157 https://reactome.org/PathwayBrowser/#/R-XTR-5690157 USP16,USP21 deubiquitinate Histone H2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690159 https://reactome.org/PathwayBrowser/#/R-XTR-5690159 USP21 deubiquitinates RIPK1,DDX58 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690319 https://reactome.org/PathwayBrowser/#/R-XTR-5690319 UCHL1, UCHL3 cleave ubiquitin adducts IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-5690517 https://reactome.org/PathwayBrowser/#/R-XTR-5690517 PPT1 hydrolyses palmitoylated proteins IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5690790 https://reactome.org/PathwayBrowser/#/R-XTR-5690790 Histone H2A is dubiquitinated by the PR-DUB complex IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690808 https://reactome.org/PathwayBrowser/#/R-XTR-5690808 UCHL3, SENP8 cleave NEDD8 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5690870 https://reactome.org/PathwayBrowser/#/R-XTR-5690870 OTUD7B,TNFAIP3 deubiquitinate TRAF6 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5691381 https://reactome.org/PathwayBrowser/#/R-XTR-5691381 MYSM1 deubiquitinates Histone H2A IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5691411 https://reactome.org/PathwayBrowser/#/R-XTR-5691411 BRCA1-A complex deubiquitinates K63polyUb-histone H2A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5691439 https://reactome.org/PathwayBrowser/#/R-XTR-5691439 BRISC complex deubiquitinates NLRP3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5691507 https://reactome.org/PathwayBrowser/#/R-XTR-5691507 ASPA deacetylates NAASP to acetate and L-aspartate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5691512 https://reactome.org/PathwayBrowser/#/R-XTR-5691512 APEH hydrolyses NAc-Ser-protein IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5692462 https://reactome.org/PathwayBrowser/#/R-XTR-5692462 ATP13A1 transports Mn2+ from cytosol to ER lumen IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5692480 https://reactome.org/PathwayBrowser/#/R-XTR-5692480 ATP13A2 transports cations from cytosol to lysosomal lumen IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5692754 https://reactome.org/PathwayBrowser/#/R-XTR-5692754 CDC14A,B dephosphorylate p-3S,T MAPK6 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-5693346 https://reactome.org/PathwayBrowser/#/R-XTR-5693346 CECRI deaminates Ade-Rib to Ino IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5693373 https://reactome.org/PathwayBrowser/#/R-XTR-5693373 DDAH1 hydrolyses ADMA to DMA and L-Cit IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-5693724 https://reactome.org/PathwayBrowser/#/R-XTR-5693724 ESD dimer hydrolyses S-FGSH to GSH IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5693742 https://reactome.org/PathwayBrowser/#/R-XTR-5693742 FAAH hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 15377 R-ALL-5693747 H2O [lipid droplet] R-XTR-5693751 https://reactome.org/PathwayBrowser/#/R-XTR-5693751 FAAH2 hydrolyses AEA to AA and ETA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5693783 https://reactome.org/PathwayBrowser/#/R-XTR-5693783 NAALADases hydrolyse NAAG IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-5693807 https://reactome.org/PathwayBrowser/#/R-XTR-5693807 FUCA1 hydrolyses NGP:1,6-GlcNAc IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-5694109 https://reactome.org/PathwayBrowser/#/R-XTR-5694109 LIPC dimer hydrolyses TAG to DAG and FA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5694126 https://reactome.org/PathwayBrowser/#/R-XTR-5694126 NT5C3B hydrolyses 7MGP to 7MG IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5694137 https://reactome.org/PathwayBrowser/#/R-XTR-5694137 PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5694421 https://reactome.org/PathwayBrowser/#/R-XTR-5694421 PP6 dephosphorylates SEC24 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5694485 https://reactome.org/PathwayBrowser/#/R-XTR-5694485 ABHD3 hydrolyses LPC(14:0) to 1AGPC IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5694563 https://reactome.org/PathwayBrowser/#/R-XTR-5694563 ABHD10 hydrolyses MPAG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5694583 https://reactome.org/PathwayBrowser/#/R-XTR-5694583 ABHD4 hydrolyses NAPE IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5695964 https://reactome.org/PathwayBrowser/#/R-XTR-5695964 ABHD14B hydrolyses PNPB IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696049 https://reactome.org/PathwayBrowser/#/R-XTR-5696049 ADPRM hydrolyses ADP-ribose to R5P and AMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696119 https://reactome.org/PathwayBrowser/#/R-XTR-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5696197 https://reactome.org/PathwayBrowser/#/R-XTR-5696197 NUDT2 hydrolyses GP4G to GTP, GMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696230 https://reactome.org/PathwayBrowser/#/R-XTR-5696230 GSTO1 dimer reduces methylarsonate to methylarsonite IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-5696415 https://reactome.org/PathwayBrowser/#/R-XTR-5696415 PXLP-K278-ETNPPL tetramer hydrolyses PETA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696534 https://reactome.org/PathwayBrowser/#/R-XTR-5696534 USP18 deubiquitinates TAK1:TAB1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696564 https://reactome.org/PathwayBrowser/#/R-XTR-5696564 USP25 deubiquitinates DDX58 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696600 https://reactome.org/PathwayBrowser/#/R-XTR-5696600 USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5696605 https://reactome.org/PathwayBrowser/#/R-XTR-5696605 USP12, USP26 deubiquitinate AR IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696872 https://reactome.org/PathwayBrowser/#/R-XTR-5696872 USP30 deubiquitinates Ub-MOM proteins IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696945 https://reactome.org/PathwayBrowser/#/R-XTR-5696945 USP33 deubiquitinates CCP110,ARRB IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5696947 https://reactome.org/PathwayBrowser/#/R-XTR-5696947 USP47 deubiquitinates POLB IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5696958 https://reactome.org/PathwayBrowser/#/R-XTR-5696958 USP44 deubiquitinates CDC20 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5696960 https://reactome.org/PathwayBrowser/#/R-XTR-5696960 USP49 deubiquitinates H2B IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-5696968 https://reactome.org/PathwayBrowser/#/R-XTR-5696968 USP20, USP33 deubiquitinate ADRB2 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5696997 https://reactome.org/PathwayBrowser/#/R-XTR-5696997 USP24 deubiquitinates DDB2 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-5697009 https://reactome.org/PathwayBrowser/#/R-XTR-5697009 USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6781764 https://reactome.org/PathwayBrowser/#/R-XTR-6781764 USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-6782069 https://reactome.org/PathwayBrowser/#/R-XTR-6782069 UVSSA:USP7 deubiquitinates ERCC6 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6782106 https://reactome.org/PathwayBrowser/#/R-XTR-6782106 USP10 deubiquitinates SNX3, CFTR IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6782628 https://reactome.org/PathwayBrowser/#/R-XTR-6782628 USP8 deubiquitinates STAM2:HGS IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-6783177 https://reactome.org/PathwayBrowser/#/R-XTR-6783177 USP21 deubiquitinates GATA3,IL33 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-6784402 https://reactome.org/PathwayBrowser/#/R-XTR-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6786190 https://reactome.org/PathwayBrowser/#/R-XTR-6786190 CMBL hydrolyses OM to OLMS IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6786650 https://reactome.org/PathwayBrowser/#/R-XTR-6786650 DDHD1,2 hydrolyse PA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6787632 https://reactome.org/PathwayBrowser/#/R-XTR-6787632 GMDS dehydrates GDP-Man to GDP-DHDMan IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6788295 https://reactome.org/PathwayBrowser/#/R-XTR-6788295 HDHD1:Mg2+ dephosphorylates PURIDP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6788912 https://reactome.org/PathwayBrowser/#/R-XTR-6788912 LHPP:Mg2+ dimer hydrolyses PPi IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6792445 https://reactome.org/PathwayBrowser/#/R-XTR-6792445 LIPH, I hydrolyse PA to 2-acyl LPA IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-6792863 https://reactome.org/PathwayBrowser/#/R-XTR-6792863 PP2A-PP2R5C dephosphorylates MDM2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6797627 https://reactome.org/PathwayBrowser/#/R-XTR-6797627 ASPG hydrolyses L-Asn to L-Asp IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6797630 https://reactome.org/PathwayBrowser/#/R-XTR-6797630 LRPP4(LRPP1-3,5) hydrolyse LPA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-6797955 https://reactome.org/PathwayBrowser/#/R-XTR-6797955 ALDH7A1 oxidises BETALD to BET IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6799545 https://reactome.org/PathwayBrowser/#/R-XTR-6799545 MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-6799581 https://reactome.org/PathwayBrowser/#/R-XTR-6799581 MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6799604 https://reactome.org/PathwayBrowser/#/R-XTR-6799604 GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6799977 https://reactome.org/PathwayBrowser/#/R-XTR-6799977 PGLYRP2 hydrolyzes bacterial peptidoglycan IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6800198 https://reactome.org/PathwayBrowser/#/R-XTR-6800198 HPN heterodimer cleaves pro-MST1 to form MST1 dimer IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6800200 https://reactome.org/PathwayBrowser/#/R-XTR-6800200 HPN heterodimer cleaves pro-HGF to form HGF dimer IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-6801462 https://reactome.org/PathwayBrowser/#/R-XTR-6801462 MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6803545 https://reactome.org/PathwayBrowser/#/R-XTR-6803545 ATP7A transports cytosolic Cu2+ to phagosomal lumen IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-6803753 https://reactome.org/PathwayBrowser/#/R-XTR-6803753 NAAA hydrolyses NAEs to FAs and ethanolamine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6803789 https://reactome.org/PathwayBrowser/#/R-XTR-6803789 AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-6805650 https://reactome.org/PathwayBrowser/#/R-XTR-6805650 MTA2-NuRD complex deacetylates TP53 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6807027 https://reactome.org/PathwayBrowser/#/R-XTR-6807027 PTPN1 and PTPN2 dephosphorylate MET IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6807206 https://reactome.org/PathwayBrowser/#/R-XTR-6807206 USP13 and OTUD3 deubiquitinate PTEN IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-6807214 https://reactome.org/PathwayBrowser/#/R-XTR-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-6809263 https://reactome.org/PathwayBrowser/#/R-XTR-6809263 EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6809720 https://reactome.org/PathwayBrowser/#/R-XTR-6809720 PI3P is dephosphorylated to PI by MTM1:MTMR12 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-6810410 https://reactome.org/PathwayBrowser/#/R-XTR-6810410 PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-6810472 https://reactome.org/PathwayBrowser/#/R-XTR-6810472 NUDT13 hydrolyses AP6A to AP4 and ADP IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6813740 https://reactome.org/PathwayBrowser/#/R-XTR-6813740 GDE1 hydrolyzes GroPIns IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-6814797 https://reactome.org/PathwayBrowser/#/R-XTR-6814797 ENPP6 hydrolyzes lysophosphatidylcholine IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-69199 https://reactome.org/PathwayBrowser/#/R-XTR-69199 Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70479 https://reactome.org/PathwayBrowser/#/R-XTR-70479 FBP tetramers hydrolyze F1,6PP to Fru(6)P IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70494 https://reactome.org/PathwayBrowser/#/R-XTR-70494 Enolase dimers (ENO1,2,3) convert PEP to 2PG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70569 https://reactome.org/PathwayBrowser/#/R-XTR-70569 arginine + H2O => ornithine + urea [ARG1] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70609 https://reactome.org/PathwayBrowser/#/R-XTR-70609 glutamine + H2O => glutamate + NH4+ (GLS) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70785 https://reactome.org/PathwayBrowser/#/R-XTR-70785 beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70870 https://reactome.org/PathwayBrowser/#/R-XTR-70870 ECHS1 hydrates methacrylyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70903 https://reactome.org/PathwayBrowser/#/R-XTR-70903 urocanate + H2O => 4-imidazolone-5-propanoate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-70906 https://reactome.org/PathwayBrowser/#/R-XTR-70906 4-imidazolone-5-propanoate + H2O => N-formiminoglutamate IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71146 https://reactome.org/PathwayBrowser/#/R-XTR-71146 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71296 https://reactome.org/PathwayBrowser/#/R-XTR-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71660 https://reactome.org/PathwayBrowser/#/R-XTR-71660 Enolase dimers dehydrates 2PG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-71732 https://reactome.org/PathwayBrowser/#/R-XTR-71732 PPA1 hydrolyzes pyrophosphate to orthophosphate IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-71825 https://reactome.org/PathwayBrowser/#/R-XTR-71825 G6PC hydrolyzes G6P to Glc and Pi (liver) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73608 https://reactome.org/PathwayBrowser/#/R-XTR-73608 (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-73815 https://reactome.org/PathwayBrowser/#/R-XTR-73815 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74059 https://reactome.org/PathwayBrowser/#/R-XTR-74059 PDE6 hydrolyses cGMP to GMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74241 https://reactome.org/PathwayBrowser/#/R-XTR-74241 ADA catalyzes the deamination of (deoxy)adenosine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74247 https://reactome.org/PathwayBrowser/#/R-XTR-74247 XDH oxidizes hypoxanthine to form xanthine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74248 https://reactome.org/PathwayBrowser/#/R-XTR-74248 (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74258 https://reactome.org/PathwayBrowser/#/R-XTR-74258 XDH oxidizes xanthine to form urate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-74733 https://reactome.org/PathwayBrowser/#/R-XTR-74733 Insulin receptor de-phosphorylation IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-75899 https://reactome.org/PathwayBrowser/#/R-XTR-75899 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate IEA Xenopus tropicalis 15377 R-ALL-141343 H2O [peroxisomal matrix] R-XTR-76031 https://reactome.org/PathwayBrowser/#/R-XTR-76031 2 H2O2 => O2 + 2 H2O IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76397 https://reactome.org/PathwayBrowser/#/R-XTR-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-76590 https://reactome.org/PathwayBrowser/#/R-XTR-76590 AMP + H2O => IMP + NH4+ (AMPD) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77256 https://reactome.org/PathwayBrowser/#/R-XTR-77256 2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77277 https://reactome.org/PathwayBrowser/#/R-XTR-77277 trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77301 https://reactome.org/PathwayBrowser/#/R-XTR-77301 trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77314 https://reactome.org/PathwayBrowser/#/R-XTR-77314 Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77325 https://reactome.org/PathwayBrowser/#/R-XTR-77325 trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77333 https://reactome.org/PathwayBrowser/#/R-XTR-77333 trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-77344 https://reactome.org/PathwayBrowser/#/R-XTR-77344 trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-77615 https://reactome.org/PathwayBrowser/#/R-XTR-77615 Deamination at C6 position of adenosine in Editosome (ADAR2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848053 https://reactome.org/PathwayBrowser/#/R-XTR-8848053 ABCA5 transports CHOL from lysosomal lumen to cytosol IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848215 https://reactome.org/PathwayBrowser/#/R-XTR-8848215 ACAT2 condenses 2 Ac-CoA to form ACA-CoA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848338 https://reactome.org/PathwayBrowser/#/R-XTR-8848338 PNPLA4 hydrolyzes TAG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848339 https://reactome.org/PathwayBrowser/#/R-XTR-8848339 PNPLA5 hydrolyzes TAG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848355 https://reactome.org/PathwayBrowser/#/R-XTR-8848355 PNPLA4 hydrolyzes retinyl palmitate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8848484 https://reactome.org/PathwayBrowser/#/R-XTR-8848484 PLA2s hydrolyze phospholipids at the Golgi membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8849435 https://reactome.org/PathwayBrowser/#/R-XTR-8849435 PTPN1 dephosphorylates PTK6 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8849969 https://reactome.org/PathwayBrowser/#/R-XTR-8849969 PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8850594 https://reactome.org/PathwayBrowser/#/R-XTR-8850594 Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-ALL-2022884 H2O [Golgi lumen] R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-ALL-2022884 H2O [Golgi lumen] R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-ALL-8851517 H2O [endocytic vesicle lumen] R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8853379 https://reactome.org/PathwayBrowser/#/R-XTR-8853379 ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-8853686 https://reactome.org/PathwayBrowser/#/R-XTR-8853686 MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8854173 https://reactome.org/PathwayBrowser/#/R-XTR-8854173 TBC RabGAPs accelerate GTP hydrolysis by RAB35 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8854255 https://reactome.org/PathwayBrowser/#/R-XTR-8854255 TBC1D2A accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8854329 https://reactome.org/PathwayBrowser/#/R-XTR-8854329 TBC1D15 accelerates GTP hydrolysis by RAB7 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8854612 https://reactome.org/PathwayBrowser/#/R-XTR-8854612 TBC1D25 accelerates GTP hydrolysis by RAB33B IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-8856951 https://reactome.org/PathwayBrowser/#/R-XTR-8856951 PP2A demethylation by PPME1 IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-8862184 https://reactome.org/PathwayBrowser/#/R-XTR-8862184 USP48 cleaves polyubiquitin IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8862320 https://reactome.org/PathwayBrowser/#/R-XTR-8862320 LYZ hydrolyzes peptidoglycans in the bacterial cell wall IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8864029 https://reactome.org/PathwayBrowser/#/R-XTR-8864029 PTPN12 dephosphorylates EGFR at Y1172 (Y1148) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8864036 https://reactome.org/PathwayBrowser/#/R-XTR-8864036 PTPN12 dephosphorylates PDGFRB at Y1021 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8864125 https://reactome.org/PathwayBrowser/#/R-XTR-8864125 PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8866405 https://reactome.org/PathwayBrowser/#/R-XTR-8866405 RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8866542 https://reactome.org/PathwayBrowser/#/R-XTR-8866542 VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-8867344 https://reactome.org/PathwayBrowser/#/R-XTR-8867344 OMA1 hydrolyses OPA1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8867658 https://reactome.org/PathwayBrowser/#/R-XTR-8867658 PTPN3 dephosphorylates MAPK12 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8869206 https://reactome.org/PathwayBrowser/#/R-XTR-8869206 PAFAH2 hydrolyses PAF to lyso-PAF and acetate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8869456 https://reactome.org/PathwayBrowser/#/R-XTR-8869456 USP4 deubiquitinate TRAF2,TRAF6 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8869506 https://reactome.org/PathwayBrowser/#/R-XTR-8869506 TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8874435 https://reactome.org/PathwayBrowser/#/R-XTR-8874435 THEM86B hydrolyses PMCHO, PMETAM IEA Xenopus tropicalis 15377 R-ALL-5668574 H2O [melanosome lumen] R-XTR-8878581 https://reactome.org/PathwayBrowser/#/R-XTR-8878581 TYRP1 oxidises DHICA to IQCA IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-8878654 https://reactome.org/PathwayBrowser/#/R-XTR-8878654 ACP6 hydrolyses MYS-LPA IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8878787 https://reactome.org/PathwayBrowser/#/R-XTR-8878787 ALPI dimer hydrolyses phosphate monoesters IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8932633 https://reactome.org/PathwayBrowser/#/R-XTR-8932633 PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-893596 https://reactome.org/PathwayBrowser/#/R-XTR-893596 PXLP-KYAT1 dimer transaminates L-KYN to KYNA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-8937767 https://reactome.org/PathwayBrowser/#/R-XTR-8937767 PTPN11 dephosphorylates RUNX1 IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8940074 https://reactome.org/PathwayBrowser/#/R-XTR-8940074 NT5E:Zn2+ hydrolyses NMN IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8952137 https://reactome.org/PathwayBrowser/#/R-XTR-8952137 Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8952251 https://reactome.org/PathwayBrowser/#/R-XTR-8952251 PLA2G15 hydrolyses LPC to GPCho and LCFA(-) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-8952903 https://reactome.org/PathwayBrowser/#/R-XTR-8952903 ADPRHL2 hydrolyses poly(ADP-ribose) IEA Xenopus tropicalis 15377 R-ALL-2022884 H2O [Golgi lumen] R-XTR-8953499 https://reactome.org/PathwayBrowser/#/R-XTR-8953499 IMPAD1 hydrolyses PAP to AMP IEA Xenopus tropicalis 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-XTR-8954398 https://reactome.org/PathwayBrowser/#/R-XTR-8954398 PLD6 dimer hydrolyses cardiolipin to PA and PG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8955794 https://reactome.org/PathwayBrowser/#/R-XTR-8955794 PGP:Mg2+ dimer hydrolyses G3P to glycerol IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-8955817 https://reactome.org/PathwayBrowser/#/R-XTR-8955817 PRODH2 oxidises HPRO to 1PYR-3OH-5COOH IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-8980228 https://reactome.org/PathwayBrowser/#/R-XTR-8980228 LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8981637 https://reactome.org/PathwayBrowser/#/R-XTR-8981637 RHOA GAPs stimulate RHOA GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-8985594 https://reactome.org/PathwayBrowser/#/R-XTR-8985594 MYO9B inactivates RHOA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9013022 https://reactome.org/PathwayBrowser/#/R-XTR-9013022 RHOB GAPs stimulate RHOB GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9013144 https://reactome.org/PathwayBrowser/#/R-XTR-9013144 RAC1 GAPs stimulate RAC1 GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9013161 https://reactome.org/PathwayBrowser/#/R-XTR-9013161 CDC42 GAPs stimulate CDC42 GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9013437 https://reactome.org/PathwayBrowser/#/R-XTR-9013437 RHOD GAPs stimulate RHOD GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9014295 https://reactome.org/PathwayBrowser/#/R-XTR-9014295 RAC2 GAPs stimulate RAC2 GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9014434 https://reactome.org/PathwayBrowser/#/R-XTR-9014434 RHOG GAPs stimulate RHOG GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9014641 https://reactome.org/PathwayBrowser/#/R-XTR-9014641 HRSP12 deaminates 2-iminobutanoate to 2OBUTA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9017488 https://reactome.org/PathwayBrowser/#/R-XTR-9017488 RHOJ GAPs stimulate RHOJ GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9018745 https://reactome.org/PathwayBrowser/#/R-XTR-9018745 RHOQ GAPs stimulate RHOQ GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9018806 https://reactome.org/PathwayBrowser/#/R-XTR-9018806 RAC3 GAPs stimulate RAC3 GTPase activity IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9018826 https://reactome.org/PathwayBrowser/#/R-XTR-9018826 RHOT2 hydrolyzes GTP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9018862 https://reactome.org/PathwayBrowser/#/R-XTR-9018862 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9018877 https://reactome.org/PathwayBrowser/#/R-XTR-9018877 LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9020252 https://reactome.org/PathwayBrowser/#/R-XTR-9020252 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9020253 https://reactome.org/PathwayBrowser/#/R-XTR-9020253 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9020257 https://reactome.org/PathwayBrowser/#/R-XTR-9020257 LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9020258 https://reactome.org/PathwayBrowser/#/R-XTR-9020258 LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9020270 https://reactome.org/PathwayBrowser/#/R-XTR-9020270 LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9024890 https://reactome.org/PathwayBrowser/#/R-XTR-9024890 LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9024993 https://reactome.org/PathwayBrowser/#/R-XTR-9024993 EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9026408 https://reactome.org/PathwayBrowser/#/R-XTR-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9033491 https://reactome.org/PathwayBrowser/#/R-XTR-9033491 USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-936802 https://reactome.org/PathwayBrowser/#/R-XTR-936802 ATP7A transports cytosolic Cu2+ to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-936883 https://reactome.org/PathwayBrowser/#/R-XTR-936883 ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-936895 https://reactome.org/PathwayBrowser/#/R-XTR-936895 ATP7B transports cytosolic Cu2+ to Golgi lumen IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-936897 https://reactome.org/PathwayBrowser/#/R-XTR-936897 ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-939763 https://reactome.org/PathwayBrowser/#/R-XTR-939763 P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-947535 https://reactome.org/PathwayBrowser/#/R-XTR-947535 Cyclisation of GTP to precursor Z IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-947591 https://reactome.org/PathwayBrowser/#/R-XTR-947591 P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9624893 https://reactome.org/PathwayBrowser/#/R-XTR-9624893 RAN stimulates fusion of nuclear envelope (NE) membranes IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9638046 https://reactome.org/PathwayBrowser/#/R-XTR-9638046 ACY3:Zn2+ dimer hydrolyses mercapturic acids IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9638075 https://reactome.org/PathwayBrowser/#/R-XTR-9638075 HEXB cleaves the terminal GalNAc from DS IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9638076 https://reactome.org/PathwayBrowser/#/R-XTR-9638076 HEXB cleaves the terminal GalNAc from small HA fragments IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9638078 https://reactome.org/PathwayBrowser/#/R-XTR-9638078 HEXB cleaves the terminal GalNAc from keratan sulfate IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9638120 https://reactome.org/PathwayBrowser/#/R-XTR-9638120 NEU4 hydrolyses Neu5Ac from glycoconjugates IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9644869 https://reactome.org/PathwayBrowser/#/R-XTR-9644869 p-S54-PDE4B hydrolyses cAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-965067 https://reactome.org/PathwayBrowser/#/R-XTR-965067 THTPA:Mg2+ hydrolyzes ThTP to TDP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-965079 https://reactome.org/PathwayBrowser/#/R-XTR-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9656891 https://reactome.org/PathwayBrowser/#/R-XTR-9656891 OPN1SW binds 11cRAL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9656893 https://reactome.org/PathwayBrowser/#/R-XTR-9656893 OPN1MW binds 11cRAL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9661417 https://reactome.org/PathwayBrowser/#/R-XTR-9661417 ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9668419 https://reactome.org/PathwayBrowser/#/R-XTR-9668419 SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-9673053 https://reactome.org/PathwayBrowser/#/R-XTR-9673053 PM20D1 transforms oleoyl-phe from oleate and phe IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-9673054 https://reactome.org/PathwayBrowser/#/R-XTR-9673054 PM20D1 hydrolyzes oleoyl-phe IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-9686524 https://reactome.org/PathwayBrowser/#/R-XTR-9686524 PP6-PPP6R3 dephosphorylates TERF2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9693282 https://reactome.org/PathwayBrowser/#/R-XTR-9693282 RHOF GAPs stimulate RHOF GTPase activity IEA Xenopus tropicalis 15377 R-ALL-113518 H2O [nucleoplasm] R-XTR-9701565 https://reactome.org/PathwayBrowser/#/R-XTR-9701565 HDACs deacetylate p-STAT3 dimers IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9705507 https://reactome.org/PathwayBrowser/#/R-XTR-9705507 PDE3B hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9708261 https://reactome.org/PathwayBrowser/#/R-XTR-9708261 PDE4A hydrolyses cAMP to AMP IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-9709360 https://reactome.org/PathwayBrowser/#/R-XTR-9709360 H2O2 reduces MetHb IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9727567 https://reactome.org/PathwayBrowser/#/R-XTR-9727567 CES1 hydrolyses sacubitril to sacubitrilat IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-9749986 https://reactome.org/PathwayBrowser/#/R-XTR-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Xenopus tropicalis 15377 R-ALL-113519 H2O [endoplasmic reticulum lumen] R-XTR-9750016 https://reactome.org/PathwayBrowser/#/R-XTR-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9750555 https://reactome.org/PathwayBrowser/#/R-XTR-9750555 NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9750617 https://reactome.org/PathwayBrowser/#/R-XTR-9750617 ABCC5 transports TPMP substrates from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9750656 https://reactome.org/PathwayBrowser/#/R-XTR-9750656 ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9750942 https://reactome.org/PathwayBrowser/#/R-XTR-9750942 USP14 deubiquitinates NLRC5 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753278 https://reactome.org/PathwayBrowser/#/R-XTR-9753278 ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753280 https://reactome.org/PathwayBrowser/#/R-XTR-9753280 GSTs transfer GSH to NAPQI to form APAP-SG IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753283 https://reactome.org/PathwayBrowser/#/R-XTR-9753283 ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753284 https://reactome.org/PathwayBrowser/#/R-XTR-9753284 ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753632 https://reactome.org/PathwayBrowser/#/R-XTR-9753632 CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9753944 https://reactome.org/PathwayBrowser/#/R-XTR-9753944 ACY1:Zn2+ dimer deacetylates NAC to L-Cys IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9754964 https://reactome.org/PathwayBrowser/#/R-XTR-9754964 ADA deamidates RBV IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9755030 https://reactome.org/PathwayBrowser/#/R-XTR-9755030 ITPA dimer dephosphorylates RBV-TP to RBV-MP IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9755078 https://reactome.org/PathwayBrowser/#/R-XTR-9755078 NT5C2 tetramer dephosphorylates RBV-MP IEA Xenopus tropicalis 15377 R-ALL-109276 H2O [extracellular region] R-XTR-975593 https://reactome.org/PathwayBrowser/#/R-XTR-975593 PNLIP:CLPS hydrolyses RPALM to atROL and PALM IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-977324 https://reactome.org/PathwayBrowser/#/R-XTR-977324 PSPH:Mg2+ dimer dephosphorylates O-P-Ser IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9794120 https://reactome.org/PathwayBrowser/#/R-XTR-9794120 ABCG2 transports Cipro from intestinal cell to extracellular space IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9794572 https://reactome.org/PathwayBrowser/#/R-XTR-9794572 ABCG2 transports Cipro from hepatic cell to extracellular space IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9838289 https://reactome.org/PathwayBrowser/#/R-XTR-9838289 CLPXP degrades mitochondrial matrix proteins IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9839059 https://reactome.org/PathwayBrowser/#/R-XTR-9839059 AFG3L2:SPG7 degrades SMDT1 (EMRE) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9839105 https://reactome.org/PathwayBrowser/#/R-XTR-9839105 AFG3L2 degrades mitochondrial matrix proteins IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9839113 https://reactome.org/PathwayBrowser/#/R-XTR-9839113 AFG3L2 degrades mitochondrial inner membrane proteins IEA Xenopus tropicalis 15377 R-ALL-189422 H2O [mitochondrial intermembrane space] R-XTR-9840408 https://reactome.org/PathwayBrowser/#/R-XTR-9840408 OMA1 cleaves DELE1 IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9840795 https://reactome.org/PathwayBrowser/#/R-XTR-9840795 Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9840833 https://reactome.org/PathwayBrowser/#/R-XTR-9840833 bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer IEA Xenopus tropicalis 15377 R-ALL-1605715 H2O [lysosomal lumen] R-XTR-9840949 https://reactome.org/PathwayBrowser/#/R-XTR-9840949 ARSA removes sulfate from SM3 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9853385 https://reactome.org/PathwayBrowser/#/R-XTR-9853385 PPP1CC dephosphorylates PLK1 IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9861626 https://reactome.org/PathwayBrowser/#/R-XTR-9861626 SIRT4 cleaves lipoyl from DLAT IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9865167 https://reactome.org/PathwayBrowser/#/R-XTR-9865167 PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9865226 https://reactome.org/PathwayBrowser/#/R-XTR-9865226 PP2A dephosphorylates serine-127 of YAP1 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9915968 https://reactome.org/PathwayBrowser/#/R-XTR-9915968 8,9-EET is hydrolysed to 8.9-DHET by EPHX2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9915971 https://reactome.org/PathwayBrowser/#/R-XTR-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9915986 https://reactome.org/PathwayBrowser/#/R-XTR-9915986 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9915994 https://reactome.org/PathwayBrowser/#/R-XTR-9915994 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-9915997 https://reactome.org/PathwayBrowser/#/R-XTR-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Xenopus tropicalis 15377 R-ALL-113521 H2O [mitochondrial matrix] R-XTR-9929439 https://reactome.org/PathwayBrowser/#/R-XTR-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-997309 https://reactome.org/PathwayBrowser/#/R-XTR-997309 Dephosphorylation of STAT1 by SHP2 IEA Xenopus tropicalis 15377 R-ALL-29356 H2O [cytosol] R-XTR-997311 https://reactome.org/PathwayBrowser/#/R-XTR-997311 Dephosphorylation of TYK2 by PTP1B IEA Xenopus tropicalis 15378 R-ALL-1614597 H+ [mitochondrial inner membrane] R-AMA-1614571 https://reactome.org/PathwayBrowser/#/R-AMA-1614571 Sqr oxidizes sulfide to bound persulfide TAS Arenicola marina 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-109343 https://reactome.org/PathwayBrowser/#/R-BTA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-111215 https://reactome.org/PathwayBrowser/#/R-BTA-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-111524 https://reactome.org/PathwayBrowser/#/R-BTA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-111883 https://reactome.org/PathwayBrowser/#/R-BTA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1222516 https://reactome.org/PathwayBrowser/#/R-BTA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-1222516 https://reactome.org/PathwayBrowser/#/R-BTA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Bos taurus 15378 R-ALL-2000349 H+ [phagolysosome] R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1237045 https://reactome.org/PathwayBrowser/#/R-BTA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1237047 https://reactome.org/PathwayBrowser/#/R-BTA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1237059 https://reactome.org/PathwayBrowser/#/R-BTA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1237081 https://reactome.org/PathwayBrowser/#/R-BTA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1475017 https://reactome.org/PathwayBrowser/#/R-BTA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1475022 https://reactome.org/PathwayBrowser/#/R-BTA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-1475025 https://reactome.org/PathwayBrowser/#/R-BTA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1475026 https://reactome.org/PathwayBrowser/#/R-BTA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-1475028 https://reactome.org/PathwayBrowser/#/R-BTA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-1475032 https://reactome.org/PathwayBrowser/#/R-BTA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1475435 https://reactome.org/PathwayBrowser/#/R-BTA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1475436 https://reactome.org/PathwayBrowser/#/R-BTA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1497869 https://reactome.org/PathwayBrowser/#/R-BTA-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-158609 https://reactome.org/PathwayBrowser/#/R-BTA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-159790 https://reactome.org/PathwayBrowser/#/R-BTA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-1605797 https://reactome.org/PathwayBrowser/#/R-BTA-1605797 SMPD1 hydrolyzes SPHM IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1606273 https://reactome.org/PathwayBrowser/#/R-BTA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1606288 https://reactome.org/PathwayBrowser/#/R-BTA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-1606807 https://reactome.org/PathwayBrowser/#/R-BTA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-1614362 https://reactome.org/PathwayBrowser/#/R-BTA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1614567 https://reactome.org/PathwayBrowser/#/R-BTA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1614591 https://reactome.org/PathwayBrowser/#/R-BTA-1614591 Excess cysteine yields lanthionine and H2S IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1614614 https://reactome.org/PathwayBrowser/#/R-BTA-1614614 Cysteine is degraded to pyruvate and H2S IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1614631 https://reactome.org/PathwayBrowser/#/R-BTA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-162730 https://reactome.org/PathwayBrowser/#/R-BTA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-163120 https://reactome.org/PathwayBrowser/#/R-BTA-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-163217 https://reactome.org/PathwayBrowser/#/R-BTA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-1638104 https://reactome.org/PathwayBrowser/#/R-BTA-1638104 UGCG transfers glucose to ceramide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1638845 https://reactome.org/PathwayBrowser/#/R-BTA-1638845 CERK phosphorylates CERA to form C1P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1640164 https://reactome.org/PathwayBrowser/#/R-BTA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-164651 https://reactome.org/PathwayBrowser/#/R-BTA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-164834 https://reactome.org/PathwayBrowser/#/R-BTA-164834 Enzyme-bound ATP is released IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-164834 https://reactome.org/PathwayBrowser/#/R-BTA-164834 Enzyme-bound ATP is released IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-1655879 https://reactome.org/PathwayBrowser/#/R-BTA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Bos taurus 15378 R-ALL-9631150 H+ [endolysosome lumen] R-BTA-1678920 https://reactome.org/PathwayBrowser/#/R-BTA-1678920 TLR processing at low pH IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 UCP1 imports a proton IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-170026 https://reactome.org/PathwayBrowser/#/R-BTA-170026 UCP1 imports a proton IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-173597 https://reactome.org/PathwayBrowser/#/R-BTA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-174389 https://reactome.org/PathwayBrowser/#/R-BTA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-174392 https://reactome.org/PathwayBrowser/#/R-BTA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-174438 https://reactome.org/PathwayBrowser/#/R-BTA-174438 Formation of the Flap Intermediate on the C-strand IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-189425 https://reactome.org/PathwayBrowser/#/R-BTA-189425 UROD decarboxylates URO3 to COPRO3 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-189439 https://reactome.org/PathwayBrowser/#/R-BTA-189439 ALAD condenses 2 dALAs to form PBG IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-189442 https://reactome.org/PathwayBrowser/#/R-BTA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-189465 https://reactome.org/PathwayBrowser/#/R-BTA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-190182 https://reactome.org/PathwayBrowser/#/R-BTA-190182 UROD decarboxylates URO1 to COPRO1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-191323 https://reactome.org/PathwayBrowser/#/R-BTA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-191352 https://reactome.org/PathwayBrowser/#/R-BTA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-191402 https://reactome.org/PathwayBrowser/#/R-BTA-191402 Reduction of presqualene diphosphate to form squalene IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192033 https://reactome.org/PathwayBrowser/#/R-BTA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192036 https://reactome.org/PathwayBrowser/#/R-BTA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-192042 https://reactome.org/PathwayBrowser/#/R-BTA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192067 https://reactome.org/PathwayBrowser/#/R-BTA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192097 https://reactome.org/PathwayBrowser/#/R-BTA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192160 https://reactome.org/PathwayBrowser/#/R-BTA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193064 https://reactome.org/PathwayBrowser/#/R-BTA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193073 https://reactome.org/PathwayBrowser/#/R-BTA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-193455 https://reactome.org/PathwayBrowser/#/R-BTA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193497 https://reactome.org/PathwayBrowser/#/R-BTA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-193508 https://reactome.org/PathwayBrowser/#/R-BTA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193746 https://reactome.org/PathwayBrowser/#/R-BTA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193755 https://reactome.org/PathwayBrowser/#/R-BTA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193758 https://reactome.org/PathwayBrowser/#/R-BTA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193781 https://reactome.org/PathwayBrowser/#/R-BTA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193789 https://reactome.org/PathwayBrowser/#/R-BTA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193800 https://reactome.org/PathwayBrowser/#/R-BTA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193816 https://reactome.org/PathwayBrowser/#/R-BTA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193821 https://reactome.org/PathwayBrowser/#/R-BTA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193824 https://reactome.org/PathwayBrowser/#/R-BTA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193841 https://reactome.org/PathwayBrowser/#/R-BTA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194023 https://reactome.org/PathwayBrowser/#/R-BTA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194632 https://reactome.org/PathwayBrowser/#/R-BTA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194642 https://reactome.org/PathwayBrowser/#/R-BTA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-ALL-194688 H+ [nuclear envelope] R-BTA-194674 https://reactome.org/PathwayBrowser/#/R-BTA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194689 https://reactome.org/PathwayBrowser/#/R-BTA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194698 https://reactome.org/PathwayBrowser/#/R-BTA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-194718 https://reactome.org/PathwayBrowser/#/R-BTA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196060 https://reactome.org/PathwayBrowser/#/R-BTA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196350 https://reactome.org/PathwayBrowser/#/R-BTA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196372 https://reactome.org/PathwayBrowser/#/R-BTA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196402 https://reactome.org/PathwayBrowser/#/R-BTA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196417 https://reactome.org/PathwayBrowser/#/R-BTA-196417 Reduction of desmosterol to cholesterol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196753 https://reactome.org/PathwayBrowser/#/R-BTA-196753 2xPPCS ligates PPanK with Cys IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196754 https://reactome.org/PathwayBrowser/#/R-BTA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196773 https://reactome.org/PathwayBrowser/#/R-BTA-196773 COASY phosphorylates DP-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196840 https://reactome.org/PathwayBrowser/#/R-BTA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196857 https://reactome.org/PathwayBrowser/#/R-BTA-196857 PANK2 phosphorylates PanK IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196929 https://reactome.org/PathwayBrowser/#/R-BTA-196929 FLAD1 phosphorylates FMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196955 https://reactome.org/PathwayBrowser/#/R-BTA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-196964 https://reactome.org/PathwayBrowser/#/R-BTA-196964 RFK:Mg2+ phosphorylates RIB IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197198 https://reactome.org/PathwayBrowser/#/R-BTA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197235 https://reactome.org/PathwayBrowser/#/R-BTA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197250 https://reactome.org/PathwayBrowser/#/R-BTA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197268 https://reactome.org/PathwayBrowser/#/R-BTA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197271 https://reactome.org/PathwayBrowser/#/R-BTA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197963 https://reactome.org/PathwayBrowser/#/R-BTA-197963 DHFR2 reduces FOLA to DHF IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-197972 https://reactome.org/PathwayBrowser/#/R-BTA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-198824 https://reactome.org/PathwayBrowser/#/R-BTA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-199203 https://reactome.org/PathwayBrowser/#/R-BTA-199203 PANK1/3 phosphorylate PanK IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200423 https://reactome.org/PathwayBrowser/#/R-BTA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-200474 https://reactome.org/PathwayBrowser/#/R-BTA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-200512 https://reactome.org/PathwayBrowser/#/R-BTA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200555 https://reactome.org/PathwayBrowser/#/R-BTA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200644 https://reactome.org/PathwayBrowser/#/R-BTA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200646 https://reactome.org/PathwayBrowser/#/R-BTA-200646 Cytosolic folate export across the plasma membrane IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-200646 https://reactome.org/PathwayBrowser/#/R-BTA-200646 Cytosolic folate export across the plasma membrane IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200676 https://reactome.org/PathwayBrowser/#/R-BTA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200718 https://reactome.org/PathwayBrowser/#/R-BTA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-200729 https://reactome.org/PathwayBrowser/#/R-BTA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-200729 https://reactome.org/PathwayBrowser/#/R-BTA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-202111 https://reactome.org/PathwayBrowser/#/R-BTA-202111 AKT1 phosphorylates eNOS IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-203613 https://reactome.org/PathwayBrowser/#/R-BTA-203613 Depalmitoylation of eNOS IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-203946 https://reactome.org/PathwayBrowser/#/R-BTA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-204617 https://reactome.org/PathwayBrowser/#/R-BTA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-204647 https://reactome.org/PathwayBrowser/#/R-BTA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209772 https://reactome.org/PathwayBrowser/#/R-BTA-209772 Thyroxine is deiodinated to triiodothyronine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209821 https://reactome.org/PathwayBrowser/#/R-BTA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-209903 https://reactome.org/PathwayBrowser/#/R-BTA-209903 Noradrenaline is converted to adrenaline IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-209973 https://reactome.org/PathwayBrowser/#/R-BTA-209973 Tyrosine is diiodinated IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-210404 https://reactome.org/PathwayBrowser/#/R-BTA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161187 https://reactome.org/PathwayBrowser/#/R-BTA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161549 https://reactome.org/PathwayBrowser/#/R-BTA-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161614 https://reactome.org/PathwayBrowser/#/R-BTA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161651 https://reactome.org/PathwayBrowser/#/R-BTA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161779 https://reactome.org/PathwayBrowser/#/R-BTA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2162078 https://reactome.org/PathwayBrowser/#/R-BTA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162186 https://reactome.org/PathwayBrowser/#/R-BTA-2162186 COQ3 methylates DeMQ10H2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162187 https://reactome.org/PathwayBrowser/#/R-BTA-2162187 COQ6 hydroxylates DHB IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162188 https://reactome.org/PathwayBrowser/#/R-BTA-2162188 COQ5 methylates MDMQ10H2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162193 https://reactome.org/PathwayBrowser/#/R-BTA-2162193 COQ3 methylates DHDB IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2162195 https://reactome.org/PathwayBrowser/#/R-BTA-2162195 COQ4 decarboxylates MHDB IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2395512 https://reactome.org/PathwayBrowser/#/R-BTA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2395517 https://reactome.org/PathwayBrowser/#/R-BTA-2395517 NADPH transfers electrons to FDXR IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395818 https://reactome.org/PathwayBrowser/#/R-BTA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395849 https://reactome.org/PathwayBrowser/#/R-BTA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395869 https://reactome.org/PathwayBrowser/#/R-BTA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395872 https://reactome.org/PathwayBrowser/#/R-BTA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395873 https://reactome.org/PathwayBrowser/#/R-BTA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395876 https://reactome.org/PathwayBrowser/#/R-BTA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395879 https://reactome.org/PathwayBrowser/#/R-BTA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2395965 https://reactome.org/PathwayBrowser/#/R-BTA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2408524 https://reactome.org/PathwayBrowser/#/R-BTA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2408527 https://reactome.org/PathwayBrowser/#/R-BTA-2408527 SeO3(2-) is reduced to H2Se by TXNRD1 TAS Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2453833 https://reactome.org/PathwayBrowser/#/R-BTA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2454081 https://reactome.org/PathwayBrowser/#/R-BTA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2464776 https://reactome.org/PathwayBrowser/#/R-BTA-2464776 Rdh8 reduces atRAL to atROL TAS Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2464822 https://reactome.org/PathwayBrowser/#/R-BTA-2464822 RDH12 reduces atRAL to atROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2465940 https://reactome.org/PathwayBrowser/#/R-BTA-2465940 atRAL is reduced to atROL IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-2509793 https://reactome.org/PathwayBrowser/#/R-BTA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-2509816 https://reactome.org/PathwayBrowser/#/R-BTA-2509816 NUDT16 hydrolyses IDP to IMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2509827 https://reactome.org/PathwayBrowser/#/R-BTA-2509827 ITPA hydrolyses ITP to IMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2509831 https://reactome.org/PathwayBrowser/#/R-BTA-2509831 ITPA hydrolyses XTP to XMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2509838 https://reactome.org/PathwayBrowser/#/R-BTA-2509838 ITPA hydrolyses dITP to dIMP IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-2534378 https://reactome.org/PathwayBrowser/#/R-BTA-2534378 Hv1 Mediated H+ Permeability IEA Bos taurus 15378 R-ALL-1132304 H+ [cytoplasm] R-BTA-2534378 https://reactome.org/PathwayBrowser/#/R-BTA-2534378 Hv1 Mediated H+ Permeability IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-BTA-264615 https://reactome.org/PathwayBrowser/#/R-BTA-264615 Loading of acetylcholine in synaptic vesicles IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-266070 https://reactome.org/PathwayBrowser/#/R-BTA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-2671885 https://reactome.org/PathwayBrowser/#/R-BTA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2730692 https://reactome.org/PathwayBrowser/#/R-BTA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Bos taurus 15378 R-ALL-74722 H+ [endosome lumen] R-BTA-2730692 https://reactome.org/PathwayBrowser/#/R-BTA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2730959 https://reactome.org/PathwayBrowser/#/R-BTA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-2730959 https://reactome.org/PathwayBrowser/#/R-BTA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2855252 https://reactome.org/PathwayBrowser/#/R-BTA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-2872444 https://reactome.org/PathwayBrowser/#/R-BTA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-2872444 https://reactome.org/PathwayBrowser/#/R-BTA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-2889070 https://reactome.org/PathwayBrowser/#/R-BTA-2889070 SLC9B2 exchanges Na+ for H+ IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-2889070 https://reactome.org/PathwayBrowser/#/R-BTA-2889070 SLC9B2 exchanges Na+ for H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3095889 https://reactome.org/PathwayBrowser/#/R-BTA-3095889 MMACHC dealkylates RCbl IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3149518 https://reactome.org/PathwayBrowser/#/R-BTA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3149519 https://reactome.org/PathwayBrowser/#/R-BTA-3149519 MMACHC decyanates CNCbl IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-3159253 https://reactome.org/PathwayBrowser/#/R-BTA-3159253 MMAB adenosylates cob(I)alamin IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322001 https://reactome.org/PathwayBrowser/#/R-BTA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322003 https://reactome.org/PathwayBrowser/#/R-BTA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322009 https://reactome.org/PathwayBrowser/#/R-BTA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322014 https://reactome.org/PathwayBrowser/#/R-BTA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322019 https://reactome.org/PathwayBrowser/#/R-BTA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322025 https://reactome.org/PathwayBrowser/#/R-BTA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3322041 https://reactome.org/PathwayBrowser/#/R-BTA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-3323050 https://reactome.org/PathwayBrowser/#/R-BTA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-3323079 https://reactome.org/PathwayBrowser/#/R-BTA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-350869 https://reactome.org/PathwayBrowser/#/R-BTA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-350901 https://reactome.org/PathwayBrowser/#/R-BTA-350901 Iodide is organified IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-352174 https://reactome.org/PathwayBrowser/#/R-BTA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-352182 https://reactome.org/PathwayBrowser/#/R-BTA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-372448 https://reactome.org/PathwayBrowser/#/R-BTA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-373867 https://reactome.org/PathwayBrowser/#/R-BTA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-373875 https://reactome.org/PathwayBrowser/#/R-BTA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-375405 https://reactome.org/PathwayBrowser/#/R-BTA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-375405 https://reactome.org/PathwayBrowser/#/R-BTA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-375417 https://reactome.org/PathwayBrowser/#/R-BTA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3780994 https://reactome.org/PathwayBrowser/#/R-BTA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-3781024 https://reactome.org/PathwayBrowser/#/R-BTA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-379048 https://reactome.org/PathwayBrowser/#/R-BTA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-380608 https://reactome.org/PathwayBrowser/#/R-BTA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-389540 https://reactome.org/PathwayBrowser/#/R-BTA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-389550 https://reactome.org/PathwayBrowser/#/R-BTA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-389609 https://reactome.org/PathwayBrowser/#/R-BTA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-389826 https://reactome.org/PathwayBrowser/#/R-BTA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-389995 https://reactome.org/PathwayBrowser/#/R-BTA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-390251 https://reactome.org/PathwayBrowser/#/R-BTA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-390304 https://reactome.org/PathwayBrowser/#/R-BTA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-390393 https://reactome.org/PathwayBrowser/#/R-BTA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-390425 https://reactome.org/PathwayBrowser/#/R-BTA-390425 FAR1 reduces PalmCoA to HXOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-390438 https://reactome.org/PathwayBrowser/#/R-BTA-390438 FAR2 reduces PalmCoA to HXOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-418365 https://reactome.org/PathwayBrowser/#/R-BTA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Bos taurus 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-BTA-418365 https://reactome.org/PathwayBrowser/#/R-BTA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-425577 https://reactome.org/PathwayBrowser/#/R-BTA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-425965 https://reactome.org/PathwayBrowser/#/R-BTA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Bos taurus 15378 R-ALL-425999 H+ [late endosome lumen] R-BTA-425965 https://reactome.org/PathwayBrowser/#/R-BTA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-425983 https://reactome.org/PathwayBrowser/#/R-BTA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Bos taurus 15378 R-ALL-425978 H+ [early endosome lumen] R-BTA-425983 https://reactome.org/PathwayBrowser/#/R-BTA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-425994 https://reactome.org/PathwayBrowser/#/R-BTA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-425994 https://reactome.org/PathwayBrowser/#/R-BTA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-426015 https://reactome.org/PathwayBrowser/#/R-BTA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-426015 https://reactome.org/PathwayBrowser/#/R-BTA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-426043 https://reactome.org/PathwayBrowser/#/R-BTA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-427555 https://reactome.org/PathwayBrowser/#/R-BTA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-427555 https://reactome.org/PathwayBrowser/#/R-BTA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-427910 https://reactome.org/PathwayBrowser/#/R-BTA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-427910 https://reactome.org/PathwayBrowser/#/R-BTA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-427998 https://reactome.org/PathwayBrowser/#/R-BTA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-428007 https://reactome.org/PathwayBrowser/#/R-BTA-428007 Proton-coupled histidine and di-peptide cotransport IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-428015 https://reactome.org/PathwayBrowser/#/R-BTA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428052 https://reactome.org/PathwayBrowser/#/R-BTA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Bos taurus 15378 R-ALL-428548 H+ [synaptic vesicle] R-BTA-428052 https://reactome.org/PathwayBrowser/#/R-BTA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428123 https://reactome.org/PathwayBrowser/#/R-BTA-428123 KDSR reduces 3-ketosphingoid IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428127 https://reactome.org/PathwayBrowser/#/R-BTA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428185 https://reactome.org/PathwayBrowser/#/R-BTA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428273 https://reactome.org/PathwayBrowser/#/R-BTA-428273 SPHK1 phosphorylates sphingoid IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428585 https://reactome.org/PathwayBrowser/#/R-BTA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-428585 https://reactome.org/PathwayBrowser/#/R-BTA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-428625 https://reactome.org/PathwayBrowser/#/R-BTA-428625 Vesicular inhibitory amino acid transport IEA Bos taurus 15378 R-ALL-428548 H+ [synaptic vesicle] R-BTA-428625 https://reactome.org/PathwayBrowser/#/R-BTA-428625 Vesicular inhibitory amino acid transport IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-429016 https://reactome.org/PathwayBrowser/#/R-BTA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-429101 https://reactome.org/PathwayBrowser/#/R-BTA-429101 HMIT co-transports myo-inositol with a proton IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-429101 https://reactome.org/PathwayBrowser/#/R-BTA-429101 HMIT co-transports myo-inositol with a proton IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-429157 https://reactome.org/PathwayBrowser/#/R-BTA-429157 ABCC4 accumulation of dense granule contents IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-429698 https://reactome.org/PathwayBrowser/#/R-BTA-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-429714 https://reactome.org/PathwayBrowser/#/R-BTA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-433698 https://reactome.org/PathwayBrowser/#/R-BTA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-434650 https://reactome.org/PathwayBrowser/#/R-BTA-434650 MATEs mediate extrusion of xenobiotics IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-435171 https://reactome.org/PathwayBrowser/#/R-BTA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-435349 https://reactome.org/PathwayBrowser/#/R-BTA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-435349 https://reactome.org/PathwayBrowser/#/R-BTA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-444393 https://reactome.org/PathwayBrowser/#/R-BTA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-444393 https://reactome.org/PathwayBrowser/#/R-BTA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-444419 https://reactome.org/PathwayBrowser/#/R-BTA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-444419 https://reactome.org/PathwayBrowser/#/R-BTA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-444731 https://reactome.org/PathwayBrowser/#/R-BTA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-446195 https://reactome.org/PathwayBrowser/#/R-BTA-446195 DOLK phosphorylates DCHOL to DOLP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-446200 https://reactome.org/PathwayBrowser/#/R-BTA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-446221 https://reactome.org/PathwayBrowser/#/R-BTA-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-446277 https://reactome.org/PathwayBrowser/#/R-BTA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-446277 https://reactome.org/PathwayBrowser/#/R-BTA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-446278 https://reactome.org/PathwayBrowser/#/R-BTA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-446278 https://reactome.org/PathwayBrowser/#/R-BTA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-450971 https://reactome.org/PathwayBrowser/#/R-BTA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-469659 https://reactome.org/PathwayBrowser/#/R-BTA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-504054 https://reactome.org/PathwayBrowser/#/R-BTA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-508040 https://reactome.org/PathwayBrowser/#/R-BTA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-508308 https://reactome.org/PathwayBrowser/#/R-BTA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-508369 https://reactome.org/PathwayBrowser/#/R-BTA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-508473 https://reactome.org/PathwayBrowser/#/R-BTA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-514604 https://reactome.org/PathwayBrowser/#/R-BTA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5263614 https://reactome.org/PathwayBrowser/#/R-BTA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5263616 https://reactome.org/PathwayBrowser/#/R-BTA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5340130 https://reactome.org/PathwayBrowser/#/R-BTA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-5340130 https://reactome.org/PathwayBrowser/#/R-BTA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5362518 https://reactome.org/PathwayBrowser/#/R-BTA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5362522 https://reactome.org/PathwayBrowser/#/R-BTA-5362522 ALDHs oxidise atRAL to atRA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5362564 https://reactome.org/PathwayBrowser/#/R-BTA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5362721 https://reactome.org/PathwayBrowser/#/R-BTA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5419165 https://reactome.org/PathwayBrowser/#/R-BTA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5423637 https://reactome.org/PathwayBrowser/#/R-BTA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-548800 https://reactome.org/PathwayBrowser/#/R-BTA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-548814 https://reactome.org/PathwayBrowser/#/R-BTA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-548815 https://reactome.org/PathwayBrowser/#/R-BTA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-548818 https://reactome.org/PathwayBrowser/#/R-BTA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-548831 https://reactome.org/PathwayBrowser/#/R-BTA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5615668 https://reactome.org/PathwayBrowser/#/R-BTA-5615668 AKR1C3 reduces atRAL to atROL IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-5623643 https://reactome.org/PathwayBrowser/#/R-BTA-5623643 RDH13 reduces atRAL to atROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5652172 https://reactome.org/PathwayBrowser/#/R-BTA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5652195 https://reactome.org/PathwayBrowser/#/R-BTA-5652195 SORD oxidizes D-sorbitol to Fru IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5661240 https://reactome.org/PathwayBrowser/#/R-BTA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5661256 https://reactome.org/PathwayBrowser/#/R-BTA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5661290 https://reactome.org/PathwayBrowser/#/R-BTA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5662471 https://reactome.org/PathwayBrowser/#/R-BTA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Bos taurus 15378 R-ALL-5668577 H+ [melanosome lumen] R-BTA-5662662 https://reactome.org/PathwayBrowser/#/R-BTA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-5690042 https://reactome.org/PathwayBrowser/#/R-BTA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-5690046 https://reactome.org/PathwayBrowser/#/R-BTA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Bos taurus 15378 R-ALL-428040 H+ [lysosomal lumen] R-BTA-5690517 https://reactome.org/PathwayBrowser/#/R-BTA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5692237 https://reactome.org/PathwayBrowser/#/R-BTA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5692261 https://reactome.org/PathwayBrowser/#/R-BTA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5692283 https://reactome.org/PathwayBrowser/#/R-BTA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5693148 https://reactome.org/PathwayBrowser/#/R-BTA-5693148 BCKDK phosphorylates BCKDH IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-5693347 https://reactome.org/PathwayBrowser/#/R-BTA-5693347 CRYM reduces P2C to PPCA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5693390 https://reactome.org/PathwayBrowser/#/R-BTA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-5693691 https://reactome.org/PathwayBrowser/#/R-BTA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5693967 https://reactome.org/PathwayBrowser/#/R-BTA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5694018 https://reactome.org/PathwayBrowser/#/R-BTA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5694462 https://reactome.org/PathwayBrowser/#/R-BTA-5694462 ABHD6,12 hydrolyse 3AG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5696021 https://reactome.org/PathwayBrowser/#/R-BTA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5696080 https://reactome.org/PathwayBrowser/#/R-BTA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5696091 https://reactome.org/PathwayBrowser/#/R-BTA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5696101 https://reactome.org/PathwayBrowser/#/R-BTA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5696457 https://reactome.org/PathwayBrowser/#/R-BTA-5696457 BDH2 dehydrogenates 3HBA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-5696822 https://reactome.org/PathwayBrowser/#/R-BTA-5696822 AKR1B15 reduces EST17b to E1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-5696838 https://reactome.org/PathwayBrowser/#/R-BTA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-597628 https://reactome.org/PathwayBrowser/#/R-BTA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6783221 https://reactome.org/PathwayBrowser/#/R-BTA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6783939 https://reactome.org/PathwayBrowser/#/R-BTA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6783955 https://reactome.org/PathwayBrowser/#/R-BTA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6784224 https://reactome.org/PathwayBrowser/#/R-BTA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6784402 https://reactome.org/PathwayBrowser/#/R-BTA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-6785933 https://reactome.org/PathwayBrowser/#/R-BTA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6786245 https://reactome.org/PathwayBrowser/#/R-BTA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6786720 https://reactome.org/PathwayBrowser/#/R-BTA-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6787642 https://reactome.org/PathwayBrowser/#/R-BTA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6787757 https://reactome.org/PathwayBrowser/#/R-BTA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6788611 https://reactome.org/PathwayBrowser/#/R-BTA-6788611 HYKK phosphorylates 5HLYS IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6788999 https://reactome.org/PathwayBrowser/#/R-BTA-6788999 HV1-mediated H+ transfer IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-6788999 https://reactome.org/PathwayBrowser/#/R-BTA-6788999 HV1-mediated H+ transfer IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-6789031 https://reactome.org/PathwayBrowser/#/R-BTA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-6789126 https://reactome.org/PathwayBrowser/#/R-BTA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6793590 https://reactome.org/PathwayBrowser/#/R-BTA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6793591 https://reactome.org/PathwayBrowser/#/R-BTA-6793591 LIAS synthesizes lipoyl-GCSH IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6798317 https://reactome.org/PathwayBrowser/#/R-BTA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6798335 https://reactome.org/PathwayBrowser/#/R-BTA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6799495 https://reactome.org/PathwayBrowser/#/R-BTA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6799722 https://reactome.org/PathwayBrowser/#/R-BTA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6801342 https://reactome.org/PathwayBrowser/#/R-BTA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6803771 https://reactome.org/PathwayBrowser/#/R-BTA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-6806647 https://reactome.org/PathwayBrowser/#/R-BTA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6806831 https://reactome.org/PathwayBrowser/#/R-BTA-6806831 CYB5Rs reduce MetHb to HbA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6806967 https://reactome.org/PathwayBrowser/#/R-BTA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6807055 https://reactome.org/PathwayBrowser/#/R-BTA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6807064 https://reactome.org/PathwayBrowser/#/R-BTA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6808464 https://reactome.org/PathwayBrowser/#/R-BTA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-6808487 https://reactome.org/PathwayBrowser/#/R-BTA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6808496 https://reactome.org/PathwayBrowser/#/R-BTA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6809264 https://reactome.org/PathwayBrowser/#/R-BTA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6809287 https://reactome.org/PathwayBrowser/#/R-BTA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6809810 https://reactome.org/PathwayBrowser/#/R-BTA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-6810474 https://reactome.org/PathwayBrowser/#/R-BTA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6810594 https://reactome.org/PathwayBrowser/#/R-BTA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6813749 https://reactome.org/PathwayBrowser/#/R-BTA-6813749 ALDH1A1 oxidises GA to DGA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-6814165 https://reactome.org/PathwayBrowser/#/R-BTA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70286 https://reactome.org/PathwayBrowser/#/R-BTA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70333 https://reactome.org/PathwayBrowser/#/R-BTA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70355 https://reactome.org/PathwayBrowser/#/R-BTA-70355 GALK1 phosphorylates Gal to Gal1P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70377 https://reactome.org/PathwayBrowser/#/R-BTA-70377 G6PD multimers dehydrogenate G6P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70420 https://reactome.org/PathwayBrowser/#/R-BTA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70449 https://reactome.org/PathwayBrowser/#/R-BTA-70449 GADPH tetramer dehydrogenates GA3P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70467 https://reactome.org/PathwayBrowser/#/R-BTA-70467 PFK tetramer phosphorylates Fru(6)P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70482 https://reactome.org/PathwayBrowser/#/R-BTA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70501 https://reactome.org/PathwayBrowser/#/R-BTA-70501 PC carboxylates PYR to OA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70510 https://reactome.org/PathwayBrowser/#/R-BTA-70510 LDH tetramer oxidises LACT to PYR IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70589 https://reactome.org/PathwayBrowser/#/R-BTA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70599 https://reactome.org/PathwayBrowser/#/R-BTA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70600 https://reactome.org/PathwayBrowser/#/R-BTA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-70606 https://reactome.org/PathwayBrowser/#/R-BTA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70664 https://reactome.org/PathwayBrowser/#/R-BTA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70670 https://reactome.org/PathwayBrowser/#/R-BTA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70679 https://reactome.org/PathwayBrowser/#/R-BTA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70745 https://reactome.org/PathwayBrowser/#/R-BTA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70773 https://reactome.org/PathwayBrowser/#/R-BTA-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70800 https://reactome.org/PathwayBrowser/#/R-BTA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70837 https://reactome.org/PathwayBrowser/#/R-BTA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70859 https://reactome.org/PathwayBrowser/#/R-BTA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70881 https://reactome.org/PathwayBrowser/#/R-BTA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70885 https://reactome.org/PathwayBrowser/#/R-BTA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70893 https://reactome.org/PathwayBrowser/#/R-BTA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70938 https://reactome.org/PathwayBrowser/#/R-BTA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70940 https://reactome.org/PathwayBrowser/#/R-BTA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70941 https://reactome.org/PathwayBrowser/#/R-BTA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70975 https://reactome.org/PathwayBrowser/#/R-BTA-70975 CS acetylates OA to citrate IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-70979 https://reactome.org/PathwayBrowser/#/R-BTA-70979 MDH2 dimer dehydrogenates MAL IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-71046 https://reactome.org/PathwayBrowser/#/R-BTA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71130 https://reactome.org/PathwayBrowser/#/R-BTA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71181 https://reactome.org/PathwayBrowser/#/R-BTA-71181 FAH cleaves 4FAA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71217 https://reactome.org/PathwayBrowser/#/R-BTA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71260 https://reactome.org/PathwayBrowser/#/R-BTA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71286 https://reactome.org/PathwayBrowser/#/R-BTA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71296 https://reactome.org/PathwayBrowser/#/R-BTA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-71401 https://reactome.org/PathwayBrowser/#/R-BTA-71401 OGDH dimer decarboxylates 2-OG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71541 https://reactome.org/PathwayBrowser/#/R-BTA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71588 https://reactome.org/PathwayBrowser/#/R-BTA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71670 https://reactome.org/PathwayBrowser/#/R-BTA-71670 PKM dephosphorylates PEP to PYR IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71682 https://reactome.org/PathwayBrowser/#/R-BTA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71691 https://reactome.org/PathwayBrowser/#/R-BTA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71707 https://reactome.org/PathwayBrowser/#/R-BTA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-71723 https://reactome.org/PathwayBrowser/#/R-BTA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71802 https://reactome.org/PathwayBrowser/#/R-BTA-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-71849 https://reactome.org/PathwayBrowser/#/R-BTA-71849 LDH tetramer reduces PYR to LACT IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73564 https://reactome.org/PathwayBrowser/#/R-BTA-73564 UMPS dimer decarboxylates OMP to UMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73571 https://reactome.org/PathwayBrowser/#/R-BTA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73573 https://reactome.org/PathwayBrowser/#/R-BTA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73577 https://reactome.org/PathwayBrowser/#/R-BTA-73577 CAD hexamer transforms L-Gln to CAP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73580 https://reactome.org/PathwayBrowser/#/R-BTA-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73585 https://reactome.org/PathwayBrowser/#/R-BTA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73589 https://reactome.org/PathwayBrowser/#/R-BTA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73591 https://reactome.org/PathwayBrowser/#/R-BTA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73596 https://reactome.org/PathwayBrowser/#/R-BTA-73596 dCMP + H2O => dUMP + NH4+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73616 https://reactome.org/PathwayBrowser/#/R-BTA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73618 https://reactome.org/PathwayBrowser/#/R-BTA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73620 https://reactome.org/PathwayBrowser/#/R-BTA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73646 https://reactome.org/PathwayBrowser/#/R-BTA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73647 https://reactome.org/PathwayBrowser/#/R-BTA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-73666 https://reactome.org/PathwayBrowser/#/R-BTA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73792 https://reactome.org/PathwayBrowser/#/R-BTA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73794 https://reactome.org/PathwayBrowser/#/R-BTA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73805 https://reactome.org/PathwayBrowser/#/R-BTA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73806 https://reactome.org/PathwayBrowser/#/R-BTA-73806 AIR + CO2 => CAIR IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73810 https://reactome.org/PathwayBrowser/#/R-BTA-73810 FGAM + ATP => AIR + ADP + Pi IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73812 https://reactome.org/PathwayBrowser/#/R-BTA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73813 https://reactome.org/PathwayBrowser/#/R-BTA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-73814 https://reactome.org/PathwayBrowser/#/R-BTA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-73912 https://reactome.org/PathwayBrowser/#/R-BTA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-73920 https://reactome.org/PathwayBrowser/#/R-BTA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-74255 https://reactome.org/PathwayBrowser/#/R-BTA-74255 Guanine + H2O => Xanthine + NH4+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-74723 https://reactome.org/PathwayBrowser/#/R-BTA-74723 Endosome acidification IEA Bos taurus 15378 R-ALL-74722 H+ [endosome lumen] R-BTA-74723 https://reactome.org/PathwayBrowser/#/R-BTA-74723 Endosome acidification IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-74872 https://reactome.org/PathwayBrowser/#/R-BTA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-749448 https://reactome.org/PathwayBrowser/#/R-BTA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-749452 https://reactome.org/PathwayBrowser/#/R-BTA-749452 The Ligand:GPCR:Gq complex dissociates IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-75851 https://reactome.org/PathwayBrowser/#/R-BTA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-75872 https://reactome.org/PathwayBrowser/#/R-BTA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-75883 https://reactome.org/PathwayBrowser/#/R-BTA-75883 DHRS7B reduces GO3P to HXDG3P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-75889 https://reactome.org/PathwayBrowser/#/R-BTA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77254 https://reactome.org/PathwayBrowser/#/R-BTA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77283 https://reactome.org/PathwayBrowser/#/R-BTA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77303 https://reactome.org/PathwayBrowser/#/R-BTA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77312 https://reactome.org/PathwayBrowser/#/R-BTA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77323 https://reactome.org/PathwayBrowser/#/R-BTA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77331 https://reactome.org/PathwayBrowser/#/R-BTA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-77342 https://reactome.org/PathwayBrowser/#/R-BTA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-804969 https://reactome.org/PathwayBrowser/#/R-BTA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8849638 https://reactome.org/PathwayBrowser/#/R-BTA-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8850846 https://reactome.org/PathwayBrowser/#/R-BTA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8850854 https://reactome.org/PathwayBrowser/#/R-BTA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851089 https://reactome.org/PathwayBrowser/#/R-BTA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851110 https://reactome.org/PathwayBrowser/#/R-BTA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851129 https://reactome.org/PathwayBrowser/#/R-BTA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-8851225 https://reactome.org/PathwayBrowser/#/R-BTA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-8851234 https://reactome.org/PathwayBrowser/#/R-BTA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851356 https://reactome.org/PathwayBrowser/#/R-BTA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851396 https://reactome.org/PathwayBrowser/#/R-BTA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-BTA-8851494 https://reactome.org/PathwayBrowser/#/R-BTA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851538 https://reactome.org/PathwayBrowser/#/R-BTA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8851550 https://reactome.org/PathwayBrowser/#/R-BTA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-8856223 https://reactome.org/PathwayBrowser/#/R-BTA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8862137 https://reactome.org/PathwayBrowser/#/R-BTA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-8862152 https://reactome.org/PathwayBrowser/#/R-BTA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8863494 https://reactome.org/PathwayBrowser/#/R-BTA-8863494 ASICs bind STOML3, (STOM) IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-8863761 https://reactome.org/PathwayBrowser/#/R-BTA-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-8866601 https://reactome.org/PathwayBrowser/#/R-BTA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8869606 https://reactome.org/PathwayBrowser/#/R-BTA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8869607 https://reactome.org/PathwayBrowser/#/R-BTA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8869627 https://reactome.org/PathwayBrowser/#/R-BTA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8869633 https://reactome.org/PathwayBrowser/#/R-BTA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8870346 https://reactome.org/PathwayBrowser/#/R-BTA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8875623 https://reactome.org/PathwayBrowser/#/R-BTA-8875623 SLC25A18,22 import L-Glu, H+ IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-8875623 https://reactome.org/PathwayBrowser/#/R-BTA-8875623 SLC25A18,22 import L-Glu, H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8876789 https://reactome.org/PathwayBrowser/#/R-BTA-8876789 CARNMT1 methylates CARN to Anserine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8876889 https://reactome.org/PathwayBrowser/#/R-BTA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-888548 https://reactome.org/PathwayBrowser/#/R-BTA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-888572 https://reactome.org/PathwayBrowser/#/R-BTA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-888577 https://reactome.org/PathwayBrowser/#/R-BTA-888577 Synthesis of GABA by GAD2 IEA Bos taurus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-BTA-8933635 https://reactome.org/PathwayBrowser/#/R-BTA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8936442 https://reactome.org/PathwayBrowser/#/R-BTA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8938076 https://reactome.org/PathwayBrowser/#/R-BTA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8939959 https://reactome.org/PathwayBrowser/#/R-BTA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8940070 https://reactome.org/PathwayBrowser/#/R-BTA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8942575 https://reactome.org/PathwayBrowser/#/R-BTA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-8952873 https://reactome.org/PathwayBrowser/#/R-BTA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-8954468 https://reactome.org/PathwayBrowser/#/R-BTA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-8955030 https://reactome.org/PathwayBrowser/#/R-BTA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8955760 https://reactome.org/PathwayBrowser/#/R-BTA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8955844 https://reactome.org/PathwayBrowser/#/R-BTA-8955844 RBKS phosphorylates ribose to R5P IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-8959719 https://reactome.org/PathwayBrowser/#/R-BTA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9009950 https://reactome.org/PathwayBrowser/#/R-BTA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9011595 https://reactome.org/PathwayBrowser/#/R-BTA-9011595 GSTZ1 dimer dehalogenates DCA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9012016 https://reactome.org/PathwayBrowser/#/R-BTA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9012036 https://reactome.org/PathwayBrowser/#/R-BTA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-9013198 https://reactome.org/PathwayBrowser/#/R-BTA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9024766 https://reactome.org/PathwayBrowser/#/R-BTA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15378 R-ALL-74722 H+ [endosome lumen] R-BTA-917811 https://reactome.org/PathwayBrowser/#/R-BTA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 15378 R-ALL-74722 H+ [endosome lumen] R-BTA-917841 https://reactome.org/PathwayBrowser/#/R-BTA-917841 Acidification of Tf:TfR1 containing endosome IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-917979 https://reactome.org/PathwayBrowser/#/R-BTA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-937311 https://reactome.org/PathwayBrowser/#/R-BTA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9619024 https://reactome.org/PathwayBrowser/#/R-BTA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-9645220 https://reactome.org/PathwayBrowser/#/R-BTA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-9650165 https://reactome.org/PathwayBrowser/#/R-BTA-9650165 ASIC trimers bind H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9695949 https://reactome.org/PathwayBrowser/#/R-BTA-9695949 SPHK2 phosphorylates sphingoid IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9705713 https://reactome.org/PathwayBrowser/#/R-BTA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9705714 https://reactome.org/PathwayBrowser/#/R-BTA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9709098 https://reactome.org/PathwayBrowser/#/R-BTA-9709098 DHFR dimer reduces FOLA to DHF IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-9727198 https://reactome.org/PathwayBrowser/#/R-BTA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9727347 https://reactome.org/PathwayBrowser/#/R-BTA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9727349 https://reactome.org/PathwayBrowser/#/R-BTA-9727349 XDH dehydrogenates xanthine to form urate IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9731228 https://reactome.org/PathwayBrowser/#/R-BTA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9731590 https://reactome.org/PathwayBrowser/#/R-BTA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9731613 https://reactome.org/PathwayBrowser/#/R-BTA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9731632 https://reactome.org/PathwayBrowser/#/R-BTA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9731661 https://reactome.org/PathwayBrowser/#/R-BTA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9748945 https://reactome.org/PathwayBrowser/#/R-BTA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9748957 https://reactome.org/PathwayBrowser/#/R-BTA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9748979 https://reactome.org/PathwayBrowser/#/R-BTA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9748983 https://reactome.org/PathwayBrowser/#/R-BTA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9748991 https://reactome.org/PathwayBrowser/#/R-BTA-9748991 XDH oxidises 6MP to 6TU IEA Bos taurus 15378 R-ALL-351626 H+ [extracellular region] R-BTA-9749609 https://reactome.org/PathwayBrowser/#/R-BTA-9749609 BCHE hydrolyzes ASA- IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9749647 https://reactome.org/PathwayBrowser/#/R-BTA-9749647 CES2 hydrolyzes ASA- IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9749792 https://reactome.org/PathwayBrowser/#/R-BTA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9755937 https://reactome.org/PathwayBrowser/#/R-BTA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756134 https://reactome.org/PathwayBrowser/#/R-BTA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756156 https://reactome.org/PathwayBrowser/#/R-BTA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756177 https://reactome.org/PathwayBrowser/#/R-BTA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9756183 https://reactome.org/PathwayBrowser/#/R-BTA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-975629 https://reactome.org/PathwayBrowser/#/R-BTA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9758661 https://reactome.org/PathwayBrowser/#/R-BTA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9758682 https://reactome.org/PathwayBrowser/#/R-BTA-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9759259 https://reactome.org/PathwayBrowser/#/R-BTA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9759549 https://reactome.org/PathwayBrowser/#/R-BTA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9760094 https://reactome.org/PathwayBrowser/#/R-BTA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-977301 https://reactome.org/PathwayBrowser/#/R-BTA-977301 Histidine is decarboxylated to histamine IEA Bos taurus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-BTA-977317 https://reactome.org/PathwayBrowser/#/R-BTA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-977348 https://reactome.org/PathwayBrowser/#/R-BTA-977348 PHGDH tetramer dehydrogenates 3PG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9773976 https://reactome.org/PathwayBrowser/#/R-BTA-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9794270 https://reactome.org/PathwayBrowser/#/R-BTA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Bos taurus 15378 R-ALL-9668967 H+ [nucleoplasm] R-BTA-9825790 https://reactome.org/PathwayBrowser/#/R-BTA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9837337 https://reactome.org/PathwayBrowser/#/R-BTA-9837337 DCAKD phosphorylates DP-CoA IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9843721 https://reactome.org/PathwayBrowser/#/R-BTA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9844587 https://reactome.org/PathwayBrowser/#/R-BTA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9844860 https://reactome.org/PathwayBrowser/#/R-BTA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9845516 https://reactome.org/PathwayBrowser/#/R-BTA-9845516 B3GALT4 transfers Gal to gangliosides IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9845538 https://reactome.org/PathwayBrowser/#/R-BTA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9845587 https://reactome.org/PathwayBrowser/#/R-BTA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9846305 https://reactome.org/PathwayBrowser/#/R-BTA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9846332 https://reactome.org/PathwayBrowser/#/R-BTA-9846332 FUT1,2 transfer fucose to gangliosides IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9846477 https://reactome.org/PathwayBrowser/#/R-BTA-9846477 A4GALT transfers galactose to LacCer IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9846501 https://reactome.org/PathwayBrowser/#/R-BTA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Bos taurus 15378 R-ALL-425969 H+ [Golgi lumen] R-BTA-9851347 https://reactome.org/PathwayBrowser/#/R-BTA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9853499 https://reactome.org/PathwayBrowser/#/R-BTA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9854315 https://reactome.org/PathwayBrowser/#/R-BTA-9854315 CSKMT methylates Citrate Synthase IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9854415 https://reactome.org/PathwayBrowser/#/R-BTA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9856871 https://reactome.org/PathwayBrowser/#/R-BTA-9856871 MDH1 reduces OA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9858321 https://reactome.org/PathwayBrowser/#/R-BTA-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9858589 https://reactome.org/PathwayBrowser/#/R-BTA-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9858590 https://reactome.org/PathwayBrowser/#/R-BTA-9858590 DLST transfers glutaryl to CoA IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9859148 https://reactome.org/PathwayBrowser/#/R-BTA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9859172 https://reactome.org/PathwayBrowser/#/R-BTA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9861616 https://reactome.org/PathwayBrowser/#/R-BTA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9861642 https://reactome.org/PathwayBrowser/#/R-BTA-9861642 NEK1 phosphorylates ME1 IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9861660 https://reactome.org/PathwayBrowser/#/R-BTA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9861734 https://reactome.org/PathwayBrowser/#/R-BTA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9864415 https://reactome.org/PathwayBrowser/#/R-BTA-9864415 AAC1 imports a proton IEA Bos taurus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-BTA-9864415 https://reactome.org/PathwayBrowser/#/R-BTA-9864415 AAC1 imports a proton IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9909159 https://reactome.org/PathwayBrowser/#/R-BTA-9909159 HK1 phosphorylates Mannose to Man6P IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9915971 https://reactome.org/PathwayBrowser/#/R-BTA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9915993 https://reactome.org/PathwayBrowser/#/R-BTA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9915997 https://reactome.org/PathwayBrowser/#/R-BTA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-BTA-9929439 https://reactome.org/PathwayBrowser/#/R-BTA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9935449 https://reactome.org/PathwayBrowser/#/R-BTA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Bos taurus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-BTA-9935469 https://reactome.org/PathwayBrowser/#/R-BTA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Bos taurus 15378 R-ALL-70106 H+ [cytosol] R-BTA-9937295 https://reactome.org/PathwayBrowser/#/R-BTA-9937295 SRD5A3 reduces polyprenal to dolichal IEA Bos taurus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-109343 https://reactome.org/PathwayBrowser/#/R-CEL-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-111524 https://reactome.org/PathwayBrowser/#/R-CEL-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1222516 https://reactome.org/PathwayBrowser/#/R-CEL-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Caenorhabditis elegans 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CEL-1222516 https://reactome.org/PathwayBrowser/#/R-CEL-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1237045 https://reactome.org/PathwayBrowser/#/R-CEL-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1237047 https://reactome.org/PathwayBrowser/#/R-CEL-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1237059 https://reactome.org/PathwayBrowser/#/R-CEL-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1237081 https://reactome.org/PathwayBrowser/#/R-CEL-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1475017 https://reactome.org/PathwayBrowser/#/R-CEL-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1475022 https://reactome.org/PathwayBrowser/#/R-CEL-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-1475025 https://reactome.org/PathwayBrowser/#/R-CEL-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1475026 https://reactome.org/PathwayBrowser/#/R-CEL-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-1475028 https://reactome.org/PathwayBrowser/#/R-CEL-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-1475032 https://reactome.org/PathwayBrowser/#/R-CEL-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1475435 https://reactome.org/PathwayBrowser/#/R-CEL-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1475436 https://reactome.org/PathwayBrowser/#/R-CEL-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15378 R-ALL-428040 H+ [lysosomal lumen] R-CEL-1605797 https://reactome.org/PathwayBrowser/#/R-CEL-1605797 SMPD1 hydrolyzes SPHM IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1606273 https://reactome.org/PathwayBrowser/#/R-CEL-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1606288 https://reactome.org/PathwayBrowser/#/R-CEL-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1614567 https://reactome.org/PathwayBrowser/#/R-CEL-1614567 Excess homocysteine yields homolanthionine and H2S IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1614591 https://reactome.org/PathwayBrowser/#/R-CEL-1614591 Excess cysteine yields lanthionine and H2S IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1614614 https://reactome.org/PathwayBrowser/#/R-CEL-1614614 Cysteine is degraded to pyruvate and H2S IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1614631 https://reactome.org/PathwayBrowser/#/R-CEL-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-1638104 https://reactome.org/PathwayBrowser/#/R-CEL-1638104 UGCG transfers glucose to ceramide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1638845 https://reactome.org/PathwayBrowser/#/R-CEL-1638845 CERK phosphorylates CERA to form C1P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1640164 https://reactome.org/PathwayBrowser/#/R-CEL-1640164 ENPP7 hydrolyzes sphingomyelin IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-164651 https://reactome.org/PathwayBrowser/#/R-CEL-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-164834 https://reactome.org/PathwayBrowser/#/R-CEL-164834 Enzyme-bound ATP is released IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-164834 https://reactome.org/PathwayBrowser/#/R-CEL-164834 Enzyme-bound ATP is released IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-169270 https://reactome.org/PathwayBrowser/#/R-CEL-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-173597 https://reactome.org/PathwayBrowser/#/R-CEL-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-174389 https://reactome.org/PathwayBrowser/#/R-CEL-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-174392 https://reactome.org/PathwayBrowser/#/R-CEL-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-189465 https://reactome.org/PathwayBrowser/#/R-CEL-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-191323 https://reactome.org/PathwayBrowser/#/R-CEL-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-191352 https://reactome.org/PathwayBrowser/#/R-CEL-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-192033 https://reactome.org/PathwayBrowser/#/R-CEL-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-192036 https://reactome.org/PathwayBrowser/#/R-CEL-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-192067 https://reactome.org/PathwayBrowser/#/R-CEL-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-192160 https://reactome.org/PathwayBrowser/#/R-CEL-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193064 https://reactome.org/PathwayBrowser/#/R-CEL-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-193455 https://reactome.org/PathwayBrowser/#/R-CEL-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-193508 https://reactome.org/PathwayBrowser/#/R-CEL-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193746 https://reactome.org/PathwayBrowser/#/R-CEL-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193755 https://reactome.org/PathwayBrowser/#/R-CEL-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193758 https://reactome.org/PathwayBrowser/#/R-CEL-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193781 https://reactome.org/PathwayBrowser/#/R-CEL-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193800 https://reactome.org/PathwayBrowser/#/R-CEL-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193821 https://reactome.org/PathwayBrowser/#/R-CEL-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193824 https://reactome.org/PathwayBrowser/#/R-CEL-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-193841 https://reactome.org/PathwayBrowser/#/R-CEL-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-194642 https://reactome.org/PathwayBrowser/#/R-CEL-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-194718 https://reactome.org/PathwayBrowser/#/R-CEL-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196060 https://reactome.org/PathwayBrowser/#/R-CEL-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196402 https://reactome.org/PathwayBrowser/#/R-CEL-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196417 https://reactome.org/PathwayBrowser/#/R-CEL-196417 Reduction of desmosterol to cholesterol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196753 https://reactome.org/PathwayBrowser/#/R-CEL-196753 2xPPCS ligates PPanK with Cys IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196754 https://reactome.org/PathwayBrowser/#/R-CEL-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196773 https://reactome.org/PathwayBrowser/#/R-CEL-196773 COASY phosphorylates DP-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196840 https://reactome.org/PathwayBrowser/#/R-CEL-196840 3xPPCDC:3FMN decarboxylates PPC IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196929 https://reactome.org/PathwayBrowser/#/R-CEL-196929 FLAD1 phosphorylates FMN IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196955 https://reactome.org/PathwayBrowser/#/R-CEL-196955 2xENPP1 hydrolyzes FAD to FMN IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-196964 https://reactome.org/PathwayBrowser/#/R-CEL-196964 RFK:Mg2+ phosphorylates RIB IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-197235 https://reactome.org/PathwayBrowser/#/R-CEL-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-197271 https://reactome.org/PathwayBrowser/#/R-CEL-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-197963 https://reactome.org/PathwayBrowser/#/R-CEL-197963 DHFR2 reduces FOLA to DHF IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-197972 https://reactome.org/PathwayBrowser/#/R-CEL-197972 DHF is reduced to tetrahydrofolate (THF) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200423 https://reactome.org/PathwayBrowser/#/R-CEL-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-200474 https://reactome.org/PathwayBrowser/#/R-CEL-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15378 R-ALL-9668967 H+ [nucleoplasm] R-CEL-200512 https://reactome.org/PathwayBrowser/#/R-CEL-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200555 https://reactome.org/PathwayBrowser/#/R-CEL-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200644 https://reactome.org/PathwayBrowser/#/R-CEL-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200646 https://reactome.org/PathwayBrowser/#/R-CEL-200646 Cytosolic folate export across the plasma membrane IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-200646 https://reactome.org/PathwayBrowser/#/R-CEL-200646 Cytosolic folate export across the plasma membrane IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200676 https://reactome.org/PathwayBrowser/#/R-CEL-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200718 https://reactome.org/PathwayBrowser/#/R-CEL-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-200729 https://reactome.org/PathwayBrowser/#/R-CEL-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-200729 https://reactome.org/PathwayBrowser/#/R-CEL-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-202111 https://reactome.org/PathwayBrowser/#/R-CEL-202111 AKT1 phosphorylates eNOS IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-203946 https://reactome.org/PathwayBrowser/#/R-CEL-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-204617 https://reactome.org/PathwayBrowser/#/R-CEL-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-204647 https://reactome.org/PathwayBrowser/#/R-CEL-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-209903 https://reactome.org/PathwayBrowser/#/R-CEL-209903 Noradrenaline is converted to adrenaline IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-209973 https://reactome.org/PathwayBrowser/#/R-CEL-209973 Tyrosine is diiodinated IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-210404 https://reactome.org/PathwayBrowser/#/R-CEL-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2161187 https://reactome.org/PathwayBrowser/#/R-CEL-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2161549 https://reactome.org/PathwayBrowser/#/R-CEL-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2161614 https://reactome.org/PathwayBrowser/#/R-CEL-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2162078 https://reactome.org/PathwayBrowser/#/R-CEL-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2162186 https://reactome.org/PathwayBrowser/#/R-CEL-2162186 COQ3 methylates DeMQ10H2 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2162187 https://reactome.org/PathwayBrowser/#/R-CEL-2162187 COQ6 hydroxylates DHB IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2162188 https://reactome.org/PathwayBrowser/#/R-CEL-2162188 COQ5 methylates MDMQ10H2 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2162193 https://reactome.org/PathwayBrowser/#/R-CEL-2162193 COQ3 methylates DHDB IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2162195 https://reactome.org/PathwayBrowser/#/R-CEL-2162195 COQ4 decarboxylates MHDB IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2395512 https://reactome.org/PathwayBrowser/#/R-CEL-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2395517 https://reactome.org/PathwayBrowser/#/R-CEL-2395517 NADPH transfers electrons to FDXR IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2395873 https://reactome.org/PathwayBrowser/#/R-CEL-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2395879 https://reactome.org/PathwayBrowser/#/R-CEL-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2395965 https://reactome.org/PathwayBrowser/#/R-CEL-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2408524 https://reactome.org/PathwayBrowser/#/R-CEL-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2453833 https://reactome.org/PathwayBrowser/#/R-CEL-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2465940 https://reactome.org/PathwayBrowser/#/R-CEL-2465940 atRAL is reduced to atROL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2509827 https://reactome.org/PathwayBrowser/#/R-CEL-2509827 ITPA hydrolyses ITP to IMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2509831 https://reactome.org/PathwayBrowser/#/R-CEL-2509831 ITPA hydrolyses XTP to XMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2509838 https://reactome.org/PathwayBrowser/#/R-CEL-2509838 ITPA hydrolyses dITP to dIMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-CEL-264615 https://reactome.org/PathwayBrowser/#/R-CEL-264615 Loading of acetylcholine in synaptic vesicles IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-266070 https://reactome.org/PathwayBrowser/#/R-CEL-266070 LTC4 is exported from the cytosol by ABCC1 IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-2671885 https://reactome.org/PathwayBrowser/#/R-CEL-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2730692 https://reactome.org/PathwayBrowser/#/R-CEL-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Caenorhabditis elegans 15378 R-ALL-74722 H+ [endosome lumen] R-CEL-2730692 https://reactome.org/PathwayBrowser/#/R-CEL-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2730959 https://reactome.org/PathwayBrowser/#/R-CEL-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Caenorhabditis elegans 15378 R-ALL-428040 H+ [lysosomal lumen] R-CEL-2730959 https://reactome.org/PathwayBrowser/#/R-CEL-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2855252 https://reactome.org/PathwayBrowser/#/R-CEL-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-2872444 https://reactome.org/PathwayBrowser/#/R-CEL-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-2872444 https://reactome.org/PathwayBrowser/#/R-CEL-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-2889070 https://reactome.org/PathwayBrowser/#/R-CEL-2889070 SLC9B2 exchanges Na+ for H+ IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-2889070 https://reactome.org/PathwayBrowser/#/R-CEL-2889070 SLC9B2 exchanges Na+ for H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3095889 https://reactome.org/PathwayBrowser/#/R-CEL-3095889 MMACHC dealkylates RCbl IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3149518 https://reactome.org/PathwayBrowser/#/R-CEL-3149518 MTRR reduces cob(II)alamin to meCbl IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3149519 https://reactome.org/PathwayBrowser/#/R-CEL-3149519 MMACHC decyanates CNCbl IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-3159253 https://reactome.org/PathwayBrowser/#/R-CEL-3159253 MMAB adenosylates cob(I)alamin IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322001 https://reactome.org/PathwayBrowser/#/R-CEL-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322003 https://reactome.org/PathwayBrowser/#/R-CEL-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322009 https://reactome.org/PathwayBrowser/#/R-CEL-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322014 https://reactome.org/PathwayBrowser/#/R-CEL-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322019 https://reactome.org/PathwayBrowser/#/R-CEL-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322025 https://reactome.org/PathwayBrowser/#/R-CEL-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3322041 https://reactome.org/PathwayBrowser/#/R-CEL-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-3323050 https://reactome.org/PathwayBrowser/#/R-CEL-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-3323079 https://reactome.org/PathwayBrowser/#/R-CEL-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-350901 https://reactome.org/PathwayBrowser/#/R-CEL-350901 Iodide is organified IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-372448 https://reactome.org/PathwayBrowser/#/R-CEL-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-373867 https://reactome.org/PathwayBrowser/#/R-CEL-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-373875 https://reactome.org/PathwayBrowser/#/R-CEL-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-375405 https://reactome.org/PathwayBrowser/#/R-CEL-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-375405 https://reactome.org/PathwayBrowser/#/R-CEL-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-375417 https://reactome.org/PathwayBrowser/#/R-CEL-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3780994 https://reactome.org/PathwayBrowser/#/R-CEL-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-3781024 https://reactome.org/PathwayBrowser/#/R-CEL-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-379048 https://reactome.org/PathwayBrowser/#/R-CEL-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-380608 https://reactome.org/PathwayBrowser/#/R-CEL-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-389540 https://reactome.org/PathwayBrowser/#/R-CEL-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-389550 https://reactome.org/PathwayBrowser/#/R-CEL-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-389609 https://reactome.org/PathwayBrowser/#/R-CEL-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-389995 https://reactome.org/PathwayBrowser/#/R-CEL-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-390251 https://reactome.org/PathwayBrowser/#/R-CEL-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-390304 https://reactome.org/PathwayBrowser/#/R-CEL-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-390393 https://reactome.org/PathwayBrowser/#/R-CEL-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-390425 https://reactome.org/PathwayBrowser/#/R-CEL-390425 FAR1 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-390438 https://reactome.org/PathwayBrowser/#/R-CEL-390438 FAR2 reduces PalmCoA to HXOL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-418365 https://reactome.org/PathwayBrowser/#/R-CEL-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Caenorhabditis elegans 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-CEL-418365 https://reactome.org/PathwayBrowser/#/R-CEL-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-425577 https://reactome.org/PathwayBrowser/#/R-CEL-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-425965 https://reactome.org/PathwayBrowser/#/R-CEL-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Caenorhabditis elegans 15378 R-ALL-425999 H+ [late endosome lumen] R-CEL-425965 https://reactome.org/PathwayBrowser/#/R-CEL-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-425983 https://reactome.org/PathwayBrowser/#/R-CEL-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Caenorhabditis elegans 15378 R-ALL-425978 H+ [early endosome lumen] R-CEL-425983 https://reactome.org/PathwayBrowser/#/R-CEL-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-425994 https://reactome.org/PathwayBrowser/#/R-CEL-425994 Na+/H+ exchanger transport (at cell membrane) IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-425994 https://reactome.org/PathwayBrowser/#/R-CEL-425994 Na+/H+ exchanger transport (at cell membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-426015 https://reactome.org/PathwayBrowser/#/R-CEL-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-426015 https://reactome.org/PathwayBrowser/#/R-CEL-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-427555 https://reactome.org/PathwayBrowser/#/R-CEL-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-427555 https://reactome.org/PathwayBrowser/#/R-CEL-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-427910 https://reactome.org/PathwayBrowser/#/R-CEL-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-427910 https://reactome.org/PathwayBrowser/#/R-CEL-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-427998 https://reactome.org/PathwayBrowser/#/R-CEL-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-428015 https://reactome.org/PathwayBrowser/#/R-CEL-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428052 https://reactome.org/PathwayBrowser/#/R-CEL-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Caenorhabditis elegans 15378 R-ALL-428548 H+ [synaptic vesicle] R-CEL-428052 https://reactome.org/PathwayBrowser/#/R-CEL-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428123 https://reactome.org/PathwayBrowser/#/R-CEL-428123 KDSR reduces 3-ketosphingoid IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428185 https://reactome.org/PathwayBrowser/#/R-CEL-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428273 https://reactome.org/PathwayBrowser/#/R-CEL-428273 SPHK1 phosphorylates sphingoid IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428585 https://reactome.org/PathwayBrowser/#/R-CEL-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-ALL-428040 H+ [lysosomal lumen] R-CEL-428585 https://reactome.org/PathwayBrowser/#/R-CEL-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-428625 https://reactome.org/PathwayBrowser/#/R-CEL-428625 Vesicular inhibitory amino acid transport IEA Caenorhabditis elegans 15378 R-ALL-428548 H+ [synaptic vesicle] R-CEL-428625 https://reactome.org/PathwayBrowser/#/R-CEL-428625 Vesicular inhibitory amino acid transport IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-429101 https://reactome.org/PathwayBrowser/#/R-CEL-429101 HMIT co-transports myo-inositol with a proton IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-429101 https://reactome.org/PathwayBrowser/#/R-CEL-429101 HMIT co-transports myo-inositol with a proton IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-429157 https://reactome.org/PathwayBrowser/#/R-CEL-429157 ABCC4 accumulation of dense granule contents IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-429698 https://reactome.org/PathwayBrowser/#/R-CEL-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-429714 https://reactome.org/PathwayBrowser/#/R-CEL-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-433698 https://reactome.org/PathwayBrowser/#/R-CEL-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CEL-435171 https://reactome.org/PathwayBrowser/#/R-CEL-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-435349 https://reactome.org/PathwayBrowser/#/R-CEL-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-435349 https://reactome.org/PathwayBrowser/#/R-CEL-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-444393 https://reactome.org/PathwayBrowser/#/R-CEL-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-444393 https://reactome.org/PathwayBrowser/#/R-CEL-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-444419 https://reactome.org/PathwayBrowser/#/R-CEL-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-444419 https://reactome.org/PathwayBrowser/#/R-CEL-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-444731 https://reactome.org/PathwayBrowser/#/R-CEL-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-446221 https://reactome.org/PathwayBrowser/#/R-CEL-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-446277 https://reactome.org/PathwayBrowser/#/R-CEL-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-446277 https://reactome.org/PathwayBrowser/#/R-CEL-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-446278 https://reactome.org/PathwayBrowser/#/R-CEL-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-446278 https://reactome.org/PathwayBrowser/#/R-CEL-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-450971 https://reactome.org/PathwayBrowser/#/R-CEL-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-469659 https://reactome.org/PathwayBrowser/#/R-CEL-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-504054 https://reactome.org/PathwayBrowser/#/R-CEL-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-508040 https://reactome.org/PathwayBrowser/#/R-CEL-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-508308 https://reactome.org/PathwayBrowser/#/R-CEL-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-508369 https://reactome.org/PathwayBrowser/#/R-CEL-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-508473 https://reactome.org/PathwayBrowser/#/R-CEL-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-514604 https://reactome.org/PathwayBrowser/#/R-CEL-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5263614 https://reactome.org/PathwayBrowser/#/R-CEL-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5263616 https://reactome.org/PathwayBrowser/#/R-CEL-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5340130 https://reactome.org/PathwayBrowser/#/R-CEL-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-ALL-428040 H+ [lysosomal lumen] R-CEL-5340130 https://reactome.org/PathwayBrowser/#/R-CEL-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5362518 https://reactome.org/PathwayBrowser/#/R-CEL-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5362522 https://reactome.org/PathwayBrowser/#/R-CEL-5362522 ALDHs oxidise atRAL to atRA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5362564 https://reactome.org/PathwayBrowser/#/R-CEL-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5362721 https://reactome.org/PathwayBrowser/#/R-CEL-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5419165 https://reactome.org/PathwayBrowser/#/R-CEL-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-548800 https://reactome.org/PathwayBrowser/#/R-CEL-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-548814 https://reactome.org/PathwayBrowser/#/R-CEL-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-548818 https://reactome.org/PathwayBrowser/#/R-CEL-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-548831 https://reactome.org/PathwayBrowser/#/R-CEL-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5615668 https://reactome.org/PathwayBrowser/#/R-CEL-5615668 AKR1C3 reduces atRAL to atROL IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-5623643 https://reactome.org/PathwayBrowser/#/R-CEL-5623643 RDH13 reduces atRAL to atROL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5652172 https://reactome.org/PathwayBrowser/#/R-CEL-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5652195 https://reactome.org/PathwayBrowser/#/R-CEL-5652195 SORD oxidizes D-sorbitol to Fru IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5661240 https://reactome.org/PathwayBrowser/#/R-CEL-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5661256 https://reactome.org/PathwayBrowser/#/R-CEL-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5661290 https://reactome.org/PathwayBrowser/#/R-CEL-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5662471 https://reactome.org/PathwayBrowser/#/R-CEL-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Caenorhabditis elegans 15378 R-ALL-5668577 H+ [melanosome lumen] R-CEL-5662662 https://reactome.org/PathwayBrowser/#/R-CEL-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-5690042 https://reactome.org/PathwayBrowser/#/R-CEL-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Caenorhabditis elegans 15378 R-ALL-428040 H+ [lysosomal lumen] R-CEL-5690517 https://reactome.org/PathwayBrowser/#/R-CEL-5690517 PPT1 hydrolyses palmitoylated proteins IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5692237 https://reactome.org/PathwayBrowser/#/R-CEL-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5692261 https://reactome.org/PathwayBrowser/#/R-CEL-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5692283 https://reactome.org/PathwayBrowser/#/R-CEL-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-5693691 https://reactome.org/PathwayBrowser/#/R-CEL-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-5693967 https://reactome.org/PathwayBrowser/#/R-CEL-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-5694018 https://reactome.org/PathwayBrowser/#/R-CEL-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5694462 https://reactome.org/PathwayBrowser/#/R-CEL-5694462 ABHD6,12 hydrolyse 3AG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5696021 https://reactome.org/PathwayBrowser/#/R-CEL-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5696080 https://reactome.org/PathwayBrowser/#/R-CEL-5696080 ALDH3B1 oxidises HXAL to PALM IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-5696091 https://reactome.org/PathwayBrowser/#/R-CEL-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-5696101 https://reactome.org/PathwayBrowser/#/R-CEL-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-5696822 https://reactome.org/PathwayBrowser/#/R-CEL-5696822 AKR1B15 reduces EST17b to E1 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-597628 https://reactome.org/PathwayBrowser/#/R-CEL-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6783221 https://reactome.org/PathwayBrowser/#/R-CEL-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6783939 https://reactome.org/PathwayBrowser/#/R-CEL-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-6784224 https://reactome.org/PathwayBrowser/#/R-CEL-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-6785933 https://reactome.org/PathwayBrowser/#/R-CEL-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6787642 https://reactome.org/PathwayBrowser/#/R-CEL-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Caenorhabditis elegans 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CEL-6789031 https://reactome.org/PathwayBrowser/#/R-CEL-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CEL-6789126 https://reactome.org/PathwayBrowser/#/R-CEL-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-6793590 https://reactome.org/PathwayBrowser/#/R-CEL-6793590 LIPT2 transfers octanoyl group to GCSH IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6799495 https://reactome.org/PathwayBrowser/#/R-CEL-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6801342 https://reactome.org/PathwayBrowser/#/R-CEL-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6803771 https://reactome.org/PathwayBrowser/#/R-CEL-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-6806967 https://reactome.org/PathwayBrowser/#/R-CEL-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6807055 https://reactome.org/PathwayBrowser/#/R-CEL-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6807064 https://reactome.org/PathwayBrowser/#/R-CEL-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-6807826 https://reactome.org/PathwayBrowser/#/R-CEL-6807826 LDHAL6B reduces PYR to LACT IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6808464 https://reactome.org/PathwayBrowser/#/R-CEL-6808464 ALDH3B2 oxidises HXAL to PALM IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-6808487 https://reactome.org/PathwayBrowser/#/R-CEL-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6808496 https://reactome.org/PathwayBrowser/#/R-CEL-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-6809264 https://reactome.org/PathwayBrowser/#/R-CEL-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-6809287 https://reactome.org/PathwayBrowser/#/R-CEL-6809287 NUDT12 hydrolyses NADH to NMNH IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-6810474 https://reactome.org/PathwayBrowser/#/R-CEL-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6813749 https://reactome.org/PathwayBrowser/#/R-CEL-6813749 ALDH1A1 oxidises GA to DGA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70286 https://reactome.org/PathwayBrowser/#/R-CEL-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70377 https://reactome.org/PathwayBrowser/#/R-CEL-70377 G6PD multimers dehydrogenate G6P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70420 https://reactome.org/PathwayBrowser/#/R-CEL-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70449 https://reactome.org/PathwayBrowser/#/R-CEL-70449 GADPH tetramer dehydrogenates GA3P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70467 https://reactome.org/PathwayBrowser/#/R-CEL-70467 PFK tetramer phosphorylates Fru(6)P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70482 https://reactome.org/PathwayBrowser/#/R-CEL-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70501 https://reactome.org/PathwayBrowser/#/R-CEL-70501 PC carboxylates PYR to OA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70510 https://reactome.org/PathwayBrowser/#/R-CEL-70510 LDH tetramer oxidises LACT to PYR IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70589 https://reactome.org/PathwayBrowser/#/R-CEL-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70599 https://reactome.org/PathwayBrowser/#/R-CEL-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70600 https://reactome.org/PathwayBrowser/#/R-CEL-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-70606 https://reactome.org/PathwayBrowser/#/R-CEL-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70664 https://reactome.org/PathwayBrowser/#/R-CEL-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70670 https://reactome.org/PathwayBrowser/#/R-CEL-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70745 https://reactome.org/PathwayBrowser/#/R-CEL-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70773 https://reactome.org/PathwayBrowser/#/R-CEL-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70800 https://reactome.org/PathwayBrowser/#/R-CEL-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70837 https://reactome.org/PathwayBrowser/#/R-CEL-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70859 https://reactome.org/PathwayBrowser/#/R-CEL-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70881 https://reactome.org/PathwayBrowser/#/R-CEL-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70885 https://reactome.org/PathwayBrowser/#/R-CEL-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70893 https://reactome.org/PathwayBrowser/#/R-CEL-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70938 https://reactome.org/PathwayBrowser/#/R-CEL-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70940 https://reactome.org/PathwayBrowser/#/R-CEL-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70941 https://reactome.org/PathwayBrowser/#/R-CEL-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70975 https://reactome.org/PathwayBrowser/#/R-CEL-70975 CS acetylates OA to citrate IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-70979 https://reactome.org/PathwayBrowser/#/R-CEL-70979 MDH2 dimer dehydrogenates MAL IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-71046 https://reactome.org/PathwayBrowser/#/R-CEL-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71130 https://reactome.org/PathwayBrowser/#/R-CEL-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71181 https://reactome.org/PathwayBrowser/#/R-CEL-71181 FAH cleaves 4FAA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71217 https://reactome.org/PathwayBrowser/#/R-CEL-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71260 https://reactome.org/PathwayBrowser/#/R-CEL-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71296 https://reactome.org/PathwayBrowser/#/R-CEL-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-71401 https://reactome.org/PathwayBrowser/#/R-CEL-71401 OGDH dimer decarboxylates 2-OG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71541 https://reactome.org/PathwayBrowser/#/R-CEL-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71670 https://reactome.org/PathwayBrowser/#/R-CEL-71670 PKM dephosphorylates PEP to PYR IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71682 https://reactome.org/PathwayBrowser/#/R-CEL-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71691 https://reactome.org/PathwayBrowser/#/R-CEL-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71707 https://reactome.org/PathwayBrowser/#/R-CEL-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-71723 https://reactome.org/PathwayBrowser/#/R-CEL-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71802 https://reactome.org/PathwayBrowser/#/R-CEL-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-71849 https://reactome.org/PathwayBrowser/#/R-CEL-71849 LDH tetramer reduces PYR to LACT IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73564 https://reactome.org/PathwayBrowser/#/R-CEL-73564 UMPS dimer decarboxylates OMP to UMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73571 https://reactome.org/PathwayBrowser/#/R-CEL-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73573 https://reactome.org/PathwayBrowser/#/R-CEL-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73577 https://reactome.org/PathwayBrowser/#/R-CEL-73577 CAD hexamer transforms L-Gln to CAP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73585 https://reactome.org/PathwayBrowser/#/R-CEL-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73589 https://reactome.org/PathwayBrowser/#/R-CEL-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73591 https://reactome.org/PathwayBrowser/#/R-CEL-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73616 https://reactome.org/PathwayBrowser/#/R-CEL-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73618 https://reactome.org/PathwayBrowser/#/R-CEL-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73620 https://reactome.org/PathwayBrowser/#/R-CEL-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73646 https://reactome.org/PathwayBrowser/#/R-CEL-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73647 https://reactome.org/PathwayBrowser/#/R-CEL-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Caenorhabditis elegans 15378 R-ALL-9668967 H+ [nucleoplasm] R-CEL-73666 https://reactome.org/PathwayBrowser/#/R-CEL-73666 dUTP + H2O => dUMP + pyrophosphate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73792 https://reactome.org/PathwayBrowser/#/R-CEL-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73794 https://reactome.org/PathwayBrowser/#/R-CEL-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73805 https://reactome.org/PathwayBrowser/#/R-CEL-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73806 https://reactome.org/PathwayBrowser/#/R-CEL-73806 AIR + CO2 => CAIR IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73810 https://reactome.org/PathwayBrowser/#/R-CEL-73810 FGAM + ATP => AIR + ADP + Pi IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73812 https://reactome.org/PathwayBrowser/#/R-CEL-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73813 https://reactome.org/PathwayBrowser/#/R-CEL-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-73814 https://reactome.org/PathwayBrowser/#/R-CEL-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-74723 https://reactome.org/PathwayBrowser/#/R-CEL-74723 Endosome acidification IEA Caenorhabditis elegans 15378 R-ALL-74722 H+ [endosome lumen] R-CEL-74723 https://reactome.org/PathwayBrowser/#/R-CEL-74723 Endosome acidification IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-749448 https://reactome.org/PathwayBrowser/#/R-CEL-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-749452 https://reactome.org/PathwayBrowser/#/R-CEL-749452 The Ligand:GPCR:Gq complex dissociates IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-75851 https://reactome.org/PathwayBrowser/#/R-CEL-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-75872 https://reactome.org/PathwayBrowser/#/R-CEL-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-75883 https://reactome.org/PathwayBrowser/#/R-CEL-75883 DHRS7B reduces GO3P to HXDG3P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-75889 https://reactome.org/PathwayBrowser/#/R-CEL-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77254 https://reactome.org/PathwayBrowser/#/R-CEL-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77283 https://reactome.org/PathwayBrowser/#/R-CEL-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77303 https://reactome.org/PathwayBrowser/#/R-CEL-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77312 https://reactome.org/PathwayBrowser/#/R-CEL-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77323 https://reactome.org/PathwayBrowser/#/R-CEL-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77331 https://reactome.org/PathwayBrowser/#/R-CEL-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-77342 https://reactome.org/PathwayBrowser/#/R-CEL-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-8851225 https://reactome.org/PathwayBrowser/#/R-CEL-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-8851234 https://reactome.org/PathwayBrowser/#/R-CEL-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-8851356 https://reactome.org/PathwayBrowser/#/R-CEL-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-8851396 https://reactome.org/PathwayBrowser/#/R-CEL-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Caenorhabditis elegans 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-CEL-8851494 https://reactome.org/PathwayBrowser/#/R-CEL-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-8863494 https://reactome.org/PathwayBrowser/#/R-CEL-8863494 ASICs bind STOML3, (STOM) IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-8863761 https://reactome.org/PathwayBrowser/#/R-CEL-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Caenorhabditis elegans 15378 R-ALL-9668967 H+ [nucleoplasm] R-CEL-8866601 https://reactome.org/PathwayBrowser/#/R-CEL-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8875623 https://reactome.org/PathwayBrowser/#/R-CEL-8875623 SLC25A18,22 import L-Glu, H+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-8875623 https://reactome.org/PathwayBrowser/#/R-CEL-8875623 SLC25A18,22 import L-Glu, H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8876889 https://reactome.org/PathwayBrowser/#/R-CEL-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-888548 https://reactome.org/PathwayBrowser/#/R-CEL-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-888572 https://reactome.org/PathwayBrowser/#/R-CEL-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-888577 https://reactome.org/PathwayBrowser/#/R-CEL-888577 Synthesis of GABA by GAD2 IEA Caenorhabditis elegans 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CEL-8933635 https://reactome.org/PathwayBrowser/#/R-CEL-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8936442 https://reactome.org/PathwayBrowser/#/R-CEL-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8939959 https://reactome.org/PathwayBrowser/#/R-CEL-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-8952873 https://reactome.org/PathwayBrowser/#/R-CEL-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-8955030 https://reactome.org/PathwayBrowser/#/R-CEL-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8955760 https://reactome.org/PathwayBrowser/#/R-CEL-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8955844 https://reactome.org/PathwayBrowser/#/R-CEL-8955844 RBKS phosphorylates ribose to R5P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8959510 https://reactome.org/PathwayBrowser/#/R-CEL-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-8959719 https://reactome.org/PathwayBrowser/#/R-CEL-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9009950 https://reactome.org/PathwayBrowser/#/R-CEL-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9011595 https://reactome.org/PathwayBrowser/#/R-CEL-9011595 GSTZ1 dimer dehalogenates DCA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9012016 https://reactome.org/PathwayBrowser/#/R-CEL-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9012036 https://reactome.org/PathwayBrowser/#/R-CEL-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-9013198 https://reactome.org/PathwayBrowser/#/R-CEL-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 15378 R-ALL-74722 H+ [endosome lumen] R-CEL-917841 https://reactome.org/PathwayBrowser/#/R-CEL-917841 Acidification of Tf:TfR1 containing endosome IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-917979 https://reactome.org/PathwayBrowser/#/R-CEL-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-9619024 https://reactome.org/PathwayBrowser/#/R-CEL-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-9645220 https://reactome.org/PathwayBrowser/#/R-CEL-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-9650165 https://reactome.org/PathwayBrowser/#/R-CEL-9650165 ASIC trimers bind H+ IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9695949 https://reactome.org/PathwayBrowser/#/R-CEL-9695949 SPHK2 phosphorylates sphingoid IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9705713 https://reactome.org/PathwayBrowser/#/R-CEL-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9705714 https://reactome.org/PathwayBrowser/#/R-CEL-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9709098 https://reactome.org/PathwayBrowser/#/R-CEL-9709098 DHFR dimer reduces FOLA to DHF IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9727347 https://reactome.org/PathwayBrowser/#/R-CEL-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9727349 https://reactome.org/PathwayBrowser/#/R-CEL-9727349 XDH dehydrogenates xanthine to form urate IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9731661 https://reactome.org/PathwayBrowser/#/R-CEL-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9748945 https://reactome.org/PathwayBrowser/#/R-CEL-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9748957 https://reactome.org/PathwayBrowser/#/R-CEL-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9748991 https://reactome.org/PathwayBrowser/#/R-CEL-9748991 XDH oxidises 6MP to 6TU IEA Caenorhabditis elegans 15378 R-ALL-351626 H+ [extracellular region] R-CEL-9749609 https://reactome.org/PathwayBrowser/#/R-CEL-9749609 BCHE hydrolyzes ASA- IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-9749647 https://reactome.org/PathwayBrowser/#/R-CEL-9749647 CES2 hydrolyzes ASA- IEA Caenorhabditis elegans 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CEL-9749792 https://reactome.org/PathwayBrowser/#/R-CEL-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9755937 https://reactome.org/PathwayBrowser/#/R-CEL-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9756177 https://reactome.org/PathwayBrowser/#/R-CEL-9756177 PON1,3 hydrolyse ATVL to ATV IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9758661 https://reactome.org/PathwayBrowser/#/R-CEL-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9758682 https://reactome.org/PathwayBrowser/#/R-CEL-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9759549 https://reactome.org/PathwayBrowser/#/R-CEL-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Caenorhabditis elegans 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CEL-977317 https://reactome.org/PathwayBrowser/#/R-CEL-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-977348 https://reactome.org/PathwayBrowser/#/R-CEL-977348 PHGDH tetramer dehydrogenates 3PG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9773976 https://reactome.org/PathwayBrowser/#/R-CEL-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9794270 https://reactome.org/PathwayBrowser/#/R-CEL-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Caenorhabditis elegans 15378 R-ALL-9668967 H+ [nucleoplasm] R-CEL-9825790 https://reactome.org/PathwayBrowser/#/R-CEL-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9837337 https://reactome.org/PathwayBrowser/#/R-CEL-9837337 DCAKD phosphorylates DP-CoA IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9843721 https://reactome.org/PathwayBrowser/#/R-CEL-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-9845516 https://reactome.org/PathwayBrowser/#/R-CEL-9845516 B3GALT4 transfers Gal to gangliosides IEA Caenorhabditis elegans 15378 R-ALL-425969 H+ [Golgi lumen] R-CEL-9846332 https://reactome.org/PathwayBrowser/#/R-CEL-9846332 FUT1,2 transfer fucose to gangliosides IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9853499 https://reactome.org/PathwayBrowser/#/R-CEL-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9854415 https://reactome.org/PathwayBrowser/#/R-CEL-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9856871 https://reactome.org/PathwayBrowser/#/R-CEL-9856871 MDH1 reduces OA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9858321 https://reactome.org/PathwayBrowser/#/R-CEL-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9858589 https://reactome.org/PathwayBrowser/#/R-CEL-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9858590 https://reactome.org/PathwayBrowser/#/R-CEL-9858590 DLST transfers glutaryl to CoA IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9859148 https://reactome.org/PathwayBrowser/#/R-CEL-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9859172 https://reactome.org/PathwayBrowser/#/R-CEL-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9861616 https://reactome.org/PathwayBrowser/#/R-CEL-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9861660 https://reactome.org/PathwayBrowser/#/R-CEL-9861660 ME1 tetramer decarboxylates OA to PYR IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9861734 https://reactome.org/PathwayBrowser/#/R-CEL-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CEL-9864415 https://reactome.org/PathwayBrowser/#/R-CEL-9864415 AAC1 imports a proton IEA Caenorhabditis elegans 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CEL-9864415 https://reactome.org/PathwayBrowser/#/R-CEL-9864415 AAC1 imports a proton IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9909159 https://reactome.org/PathwayBrowser/#/R-CEL-9909159 HK1 phosphorylates Mannose to Man6P IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9915971 https://reactome.org/PathwayBrowser/#/R-CEL-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9915997 https://reactome.org/PathwayBrowser/#/R-CEL-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9937295 https://reactome.org/PathwayBrowser/#/R-CEL-9937295 SRD5A3 reduces polyprenal to dolichal IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9937298 https://reactome.org/PathwayBrowser/#/R-CEL-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Caenorhabditis elegans 15378 R-ALL-70106 H+ [cytosol] R-CEL-9937340 https://reactome.org/PathwayBrowser/#/R-CEL-9937340 DHRSX reduces dolichal to dolichol IEA Caenorhabditis elegans 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-109343 https://reactome.org/PathwayBrowser/#/R-CFA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-111215 https://reactome.org/PathwayBrowser/#/R-CFA-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-111524 https://reactome.org/PathwayBrowser/#/R-CFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-111883 https://reactome.org/PathwayBrowser/#/R-CFA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1222516 https://reactome.org/PathwayBrowser/#/R-CFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-1222516 https://reactome.org/PathwayBrowser/#/R-CFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Canis familiaris 15378 R-ALL-2000349 H+ [phagolysosome] R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1237045 https://reactome.org/PathwayBrowser/#/R-CFA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1237047 https://reactome.org/PathwayBrowser/#/R-CFA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1237059 https://reactome.org/PathwayBrowser/#/R-CFA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1237081 https://reactome.org/PathwayBrowser/#/R-CFA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1475017 https://reactome.org/PathwayBrowser/#/R-CFA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1475022 https://reactome.org/PathwayBrowser/#/R-CFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-1475025 https://reactome.org/PathwayBrowser/#/R-CFA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1475026 https://reactome.org/PathwayBrowser/#/R-CFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-1475028 https://reactome.org/PathwayBrowser/#/R-CFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-1475032 https://reactome.org/PathwayBrowser/#/R-CFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1475435 https://reactome.org/PathwayBrowser/#/R-CFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1475436 https://reactome.org/PathwayBrowser/#/R-CFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1497869 https://reactome.org/PathwayBrowser/#/R-CFA-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-158609 https://reactome.org/PathwayBrowser/#/R-CFA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-159790 https://reactome.org/PathwayBrowser/#/R-CFA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-1605797 https://reactome.org/PathwayBrowser/#/R-CFA-1605797 SMPD1 hydrolyzes SPHM IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1606273 https://reactome.org/PathwayBrowser/#/R-CFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1606288 https://reactome.org/PathwayBrowser/#/R-CFA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-1606807 https://reactome.org/PathwayBrowser/#/R-CFA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-1614362 https://reactome.org/PathwayBrowser/#/R-CFA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1614567 https://reactome.org/PathwayBrowser/#/R-CFA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1614591 https://reactome.org/PathwayBrowser/#/R-CFA-1614591 Excess cysteine yields lanthionine and H2S IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1614614 https://reactome.org/PathwayBrowser/#/R-CFA-1614614 Cysteine is degraded to pyruvate and H2S IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1614631 https://reactome.org/PathwayBrowser/#/R-CFA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-163217 https://reactome.org/PathwayBrowser/#/R-CFA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-1638104 https://reactome.org/PathwayBrowser/#/R-CFA-1638104 UGCG transfers glucose to ceramide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1638845 https://reactome.org/PathwayBrowser/#/R-CFA-1638845 CERK phosphorylates CERA to form C1P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1640164 https://reactome.org/PathwayBrowser/#/R-CFA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-164834 https://reactome.org/PathwayBrowser/#/R-CFA-164834 Enzyme-bound ATP is released IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-1655879 https://reactome.org/PathwayBrowser/#/R-CFA-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Canis familiaris 15378 R-ALL-9631150 H+ [endolysosome lumen] R-CFA-1678920 https://reactome.org/PathwayBrowser/#/R-CFA-1678920 TLR processing at low pH IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-169270 https://reactome.org/PathwayBrowser/#/R-CFA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 UCP1 imports a proton IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-170026 https://reactome.org/PathwayBrowser/#/R-CFA-170026 UCP1 imports a proton IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-173597 https://reactome.org/PathwayBrowser/#/R-CFA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-174389 https://reactome.org/PathwayBrowser/#/R-CFA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-174392 https://reactome.org/PathwayBrowser/#/R-CFA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-174438 https://reactome.org/PathwayBrowser/#/R-CFA-174438 Formation of the Flap Intermediate on the C-strand IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-189425 https://reactome.org/PathwayBrowser/#/R-CFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-189439 https://reactome.org/PathwayBrowser/#/R-CFA-189439 ALAD condenses 2 dALAs to form PBG IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-189442 https://reactome.org/PathwayBrowser/#/R-CFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-189465 https://reactome.org/PathwayBrowser/#/R-CFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-190182 https://reactome.org/PathwayBrowser/#/R-CFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-191323 https://reactome.org/PathwayBrowser/#/R-CFA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-191352 https://reactome.org/PathwayBrowser/#/R-CFA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-191402 https://reactome.org/PathwayBrowser/#/R-CFA-191402 Reduction of presqualene diphosphate to form squalene IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192033 https://reactome.org/PathwayBrowser/#/R-CFA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-192042 https://reactome.org/PathwayBrowser/#/R-CFA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192067 https://reactome.org/PathwayBrowser/#/R-CFA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192097 https://reactome.org/PathwayBrowser/#/R-CFA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193073 https://reactome.org/PathwayBrowser/#/R-CFA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-193455 https://reactome.org/PathwayBrowser/#/R-CFA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193497 https://reactome.org/PathwayBrowser/#/R-CFA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-193508 https://reactome.org/PathwayBrowser/#/R-CFA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193746 https://reactome.org/PathwayBrowser/#/R-CFA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193755 https://reactome.org/PathwayBrowser/#/R-CFA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193789 https://reactome.org/PathwayBrowser/#/R-CFA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193816 https://reactome.org/PathwayBrowser/#/R-CFA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193821 https://reactome.org/PathwayBrowser/#/R-CFA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193824 https://reactome.org/PathwayBrowser/#/R-CFA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194023 https://reactome.org/PathwayBrowser/#/R-CFA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194632 https://reactome.org/PathwayBrowser/#/R-CFA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194642 https://reactome.org/PathwayBrowser/#/R-CFA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-ALL-194688 H+ [nuclear envelope] R-CFA-194674 https://reactome.org/PathwayBrowser/#/R-CFA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194689 https://reactome.org/PathwayBrowser/#/R-CFA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194698 https://reactome.org/PathwayBrowser/#/R-CFA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-194718 https://reactome.org/PathwayBrowser/#/R-CFA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196060 https://reactome.org/PathwayBrowser/#/R-CFA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196350 https://reactome.org/PathwayBrowser/#/R-CFA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196372 https://reactome.org/PathwayBrowser/#/R-CFA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196402 https://reactome.org/PathwayBrowser/#/R-CFA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196417 https://reactome.org/PathwayBrowser/#/R-CFA-196417 Reduction of desmosterol to cholesterol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196753 https://reactome.org/PathwayBrowser/#/R-CFA-196753 2xPPCS ligates PPanK with Cys IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196754 https://reactome.org/PathwayBrowser/#/R-CFA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196773 https://reactome.org/PathwayBrowser/#/R-CFA-196773 COASY phosphorylates DP-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196840 https://reactome.org/PathwayBrowser/#/R-CFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196857 https://reactome.org/PathwayBrowser/#/R-CFA-196857 PANK2 phosphorylates PanK IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196929 https://reactome.org/PathwayBrowser/#/R-CFA-196929 FLAD1 phosphorylates FMN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196955 https://reactome.org/PathwayBrowser/#/R-CFA-196955 2xENPP1 hydrolyzes FAD to FMN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-196964 https://reactome.org/PathwayBrowser/#/R-CFA-196964 RFK:Mg2+ phosphorylates RIB IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197198 https://reactome.org/PathwayBrowser/#/R-CFA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197235 https://reactome.org/PathwayBrowser/#/R-CFA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197250 https://reactome.org/PathwayBrowser/#/R-CFA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197268 https://reactome.org/PathwayBrowser/#/R-CFA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197271 https://reactome.org/PathwayBrowser/#/R-CFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197963 https://reactome.org/PathwayBrowser/#/R-CFA-197963 DHFR2 reduces FOLA to DHF IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-197972 https://reactome.org/PathwayBrowser/#/R-CFA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-198824 https://reactome.org/PathwayBrowser/#/R-CFA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-199203 https://reactome.org/PathwayBrowser/#/R-CFA-199203 PANK1/3 phosphorylate PanK IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200423 https://reactome.org/PathwayBrowser/#/R-CFA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-200474 https://reactome.org/PathwayBrowser/#/R-CFA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-200512 https://reactome.org/PathwayBrowser/#/R-CFA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200555 https://reactome.org/PathwayBrowser/#/R-CFA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200644 https://reactome.org/PathwayBrowser/#/R-CFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200646 https://reactome.org/PathwayBrowser/#/R-CFA-200646 Cytosolic folate export across the plasma membrane IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-200646 https://reactome.org/PathwayBrowser/#/R-CFA-200646 Cytosolic folate export across the plasma membrane IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200676 https://reactome.org/PathwayBrowser/#/R-CFA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200718 https://reactome.org/PathwayBrowser/#/R-CFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-200729 https://reactome.org/PathwayBrowser/#/R-CFA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-200729 https://reactome.org/PathwayBrowser/#/R-CFA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-203946 https://reactome.org/PathwayBrowser/#/R-CFA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-204617 https://reactome.org/PathwayBrowser/#/R-CFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-204647 https://reactome.org/PathwayBrowser/#/R-CFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209772 https://reactome.org/PathwayBrowser/#/R-CFA-209772 Thyroxine is deiodinated to triiodothyronine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209821 https://reactome.org/PathwayBrowser/#/R-CFA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-209903 https://reactome.org/PathwayBrowser/#/R-CFA-209903 Noradrenaline is converted to adrenaline IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-209973 https://reactome.org/PathwayBrowser/#/R-CFA-209973 Tyrosine is diiodinated IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-210404 https://reactome.org/PathwayBrowser/#/R-CFA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161187 https://reactome.org/PathwayBrowser/#/R-CFA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161651 https://reactome.org/PathwayBrowser/#/R-CFA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161779 https://reactome.org/PathwayBrowser/#/R-CFA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2162078 https://reactome.org/PathwayBrowser/#/R-CFA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162186 https://reactome.org/PathwayBrowser/#/R-CFA-2162186 COQ3 methylates DeMQ10H2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162187 https://reactome.org/PathwayBrowser/#/R-CFA-2162187 COQ6 hydroxylates DHB IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162188 https://reactome.org/PathwayBrowser/#/R-CFA-2162188 COQ5 methylates MDMQ10H2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162193 https://reactome.org/PathwayBrowser/#/R-CFA-2162193 COQ3 methylates DHDB IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2162195 https://reactome.org/PathwayBrowser/#/R-CFA-2162195 COQ4 decarboxylates MHDB IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2395512 https://reactome.org/PathwayBrowser/#/R-CFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2395517 https://reactome.org/PathwayBrowser/#/R-CFA-2395517 NADPH transfers electrons to FDXR IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395818 https://reactome.org/PathwayBrowser/#/R-CFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395849 https://reactome.org/PathwayBrowser/#/R-CFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395869 https://reactome.org/PathwayBrowser/#/R-CFA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395872 https://reactome.org/PathwayBrowser/#/R-CFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395873 https://reactome.org/PathwayBrowser/#/R-CFA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395876 https://reactome.org/PathwayBrowser/#/R-CFA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395879 https://reactome.org/PathwayBrowser/#/R-CFA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2395965 https://reactome.org/PathwayBrowser/#/R-CFA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2408524 https://reactome.org/PathwayBrowser/#/R-CFA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2453833 https://reactome.org/PathwayBrowser/#/R-CFA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2454081 https://reactome.org/PathwayBrowser/#/R-CFA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2464822 https://reactome.org/PathwayBrowser/#/R-CFA-2464822 RDH12 reduces atRAL to atROL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2465940 https://reactome.org/PathwayBrowser/#/R-CFA-2465940 atRAL is reduced to atROL IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-2509793 https://reactome.org/PathwayBrowser/#/R-CFA-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-2509816 https://reactome.org/PathwayBrowser/#/R-CFA-2509816 NUDT16 hydrolyses IDP to IMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2509827 https://reactome.org/PathwayBrowser/#/R-CFA-2509827 ITPA hydrolyses ITP to IMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2509831 https://reactome.org/PathwayBrowser/#/R-CFA-2509831 ITPA hydrolyses XTP to XMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2509838 https://reactome.org/PathwayBrowser/#/R-CFA-2509838 ITPA hydrolyses dITP to dIMP IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-2534378 https://reactome.org/PathwayBrowser/#/R-CFA-2534378 Hv1 Mediated H+ Permeability IEA Canis familiaris 15378 R-ALL-1132304 H+ [cytoplasm] R-CFA-2534378 https://reactome.org/PathwayBrowser/#/R-CFA-2534378 Hv1 Mediated H+ Permeability IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-CFA-264615 https://reactome.org/PathwayBrowser/#/R-CFA-264615 Loading of acetylcholine in synaptic vesicles IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-266070 https://reactome.org/PathwayBrowser/#/R-CFA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-2671885 https://reactome.org/PathwayBrowser/#/R-CFA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2730692 https://reactome.org/PathwayBrowser/#/R-CFA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Canis familiaris 15378 R-ALL-74722 H+ [endosome lumen] R-CFA-2730692 https://reactome.org/PathwayBrowser/#/R-CFA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2730959 https://reactome.org/PathwayBrowser/#/R-CFA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-2730959 https://reactome.org/PathwayBrowser/#/R-CFA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-2872444 https://reactome.org/PathwayBrowser/#/R-CFA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-2872444 https://reactome.org/PathwayBrowser/#/R-CFA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-2889070 https://reactome.org/PathwayBrowser/#/R-CFA-2889070 SLC9B2 exchanges Na+ for H+ IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-2889070 https://reactome.org/PathwayBrowser/#/R-CFA-2889070 SLC9B2 exchanges Na+ for H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3095889 https://reactome.org/PathwayBrowser/#/R-CFA-3095889 MMACHC dealkylates RCbl IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3149518 https://reactome.org/PathwayBrowser/#/R-CFA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3149519 https://reactome.org/PathwayBrowser/#/R-CFA-3149519 MMACHC decyanates CNCbl IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-3159253 https://reactome.org/PathwayBrowser/#/R-CFA-3159253 MMAB adenosylates cob(I)alamin IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322001 https://reactome.org/PathwayBrowser/#/R-CFA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322003 https://reactome.org/PathwayBrowser/#/R-CFA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322009 https://reactome.org/PathwayBrowser/#/R-CFA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322014 https://reactome.org/PathwayBrowser/#/R-CFA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322019 https://reactome.org/PathwayBrowser/#/R-CFA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322025 https://reactome.org/PathwayBrowser/#/R-CFA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3322041 https://reactome.org/PathwayBrowser/#/R-CFA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-3323079 https://reactome.org/PathwayBrowser/#/R-CFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-350901 https://reactome.org/PathwayBrowser/#/R-CFA-350901 Iodide is organified IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-352174 https://reactome.org/PathwayBrowser/#/R-CFA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-352182 https://reactome.org/PathwayBrowser/#/R-CFA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-372448 https://reactome.org/PathwayBrowser/#/R-CFA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-373867 https://reactome.org/PathwayBrowser/#/R-CFA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-373875 https://reactome.org/PathwayBrowser/#/R-CFA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-375405 https://reactome.org/PathwayBrowser/#/R-CFA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-375405 https://reactome.org/PathwayBrowser/#/R-CFA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-375417 https://reactome.org/PathwayBrowser/#/R-CFA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3780994 https://reactome.org/PathwayBrowser/#/R-CFA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-3781024 https://reactome.org/PathwayBrowser/#/R-CFA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-379048 https://reactome.org/PathwayBrowser/#/R-CFA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-380608 https://reactome.org/PathwayBrowser/#/R-CFA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-389540 https://reactome.org/PathwayBrowser/#/R-CFA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-389550 https://reactome.org/PathwayBrowser/#/R-CFA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-389609 https://reactome.org/PathwayBrowser/#/R-CFA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-389826 https://reactome.org/PathwayBrowser/#/R-CFA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-389995 https://reactome.org/PathwayBrowser/#/R-CFA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-390251 https://reactome.org/PathwayBrowser/#/R-CFA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-390304 https://reactome.org/PathwayBrowser/#/R-CFA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-390393 https://reactome.org/PathwayBrowser/#/R-CFA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-390425 https://reactome.org/PathwayBrowser/#/R-CFA-390425 FAR1 reduces PalmCoA to HXOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-390438 https://reactome.org/PathwayBrowser/#/R-CFA-390438 FAR2 reduces PalmCoA to HXOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-418365 https://reactome.org/PathwayBrowser/#/R-CFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Canis familiaris 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-CFA-418365 https://reactome.org/PathwayBrowser/#/R-CFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-425577 https://reactome.org/PathwayBrowser/#/R-CFA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-425965 https://reactome.org/PathwayBrowser/#/R-CFA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Canis familiaris 15378 R-ALL-425999 H+ [late endosome lumen] R-CFA-425965 https://reactome.org/PathwayBrowser/#/R-CFA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-425983 https://reactome.org/PathwayBrowser/#/R-CFA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Canis familiaris 15378 R-ALL-425978 H+ [early endosome lumen] R-CFA-425983 https://reactome.org/PathwayBrowser/#/R-CFA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-425994 https://reactome.org/PathwayBrowser/#/R-CFA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-425994 https://reactome.org/PathwayBrowser/#/R-CFA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-426015 https://reactome.org/PathwayBrowser/#/R-CFA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-426015 https://reactome.org/PathwayBrowser/#/R-CFA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-426043 https://reactome.org/PathwayBrowser/#/R-CFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-427555 https://reactome.org/PathwayBrowser/#/R-CFA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-427555 https://reactome.org/PathwayBrowser/#/R-CFA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-427910 https://reactome.org/PathwayBrowser/#/R-CFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-427910 https://reactome.org/PathwayBrowser/#/R-CFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-427998 https://reactome.org/PathwayBrowser/#/R-CFA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-428007 https://reactome.org/PathwayBrowser/#/R-CFA-428007 Proton-coupled histidine and di-peptide cotransport IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-428015 https://reactome.org/PathwayBrowser/#/R-CFA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428052 https://reactome.org/PathwayBrowser/#/R-CFA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Canis familiaris 15378 R-ALL-428548 H+ [synaptic vesicle] R-CFA-428052 https://reactome.org/PathwayBrowser/#/R-CFA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428123 https://reactome.org/PathwayBrowser/#/R-CFA-428123 KDSR reduces 3-ketosphingoid IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428127 https://reactome.org/PathwayBrowser/#/R-CFA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428185 https://reactome.org/PathwayBrowser/#/R-CFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428273 https://reactome.org/PathwayBrowser/#/R-CFA-428273 SPHK1 phosphorylates sphingoid IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428585 https://reactome.org/PathwayBrowser/#/R-CFA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-428585 https://reactome.org/PathwayBrowser/#/R-CFA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-428625 https://reactome.org/PathwayBrowser/#/R-CFA-428625 Vesicular inhibitory amino acid transport IEA Canis familiaris 15378 R-ALL-428548 H+ [synaptic vesicle] R-CFA-428625 https://reactome.org/PathwayBrowser/#/R-CFA-428625 Vesicular inhibitory amino acid transport IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-429101 https://reactome.org/PathwayBrowser/#/R-CFA-429101 HMIT co-transports myo-inositol with a proton IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-429101 https://reactome.org/PathwayBrowser/#/R-CFA-429101 HMIT co-transports myo-inositol with a proton IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-429157 https://reactome.org/PathwayBrowser/#/R-CFA-429157 ABCC4 accumulation of dense granule contents IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-433698 https://reactome.org/PathwayBrowser/#/R-CFA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-434650 https://reactome.org/PathwayBrowser/#/R-CFA-434650 MATEs mediate extrusion of xenobiotics IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-435171 https://reactome.org/PathwayBrowser/#/R-CFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-435349 https://reactome.org/PathwayBrowser/#/R-CFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-435349 https://reactome.org/PathwayBrowser/#/R-CFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-444393 https://reactome.org/PathwayBrowser/#/R-CFA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-444393 https://reactome.org/PathwayBrowser/#/R-CFA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-444419 https://reactome.org/PathwayBrowser/#/R-CFA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-444419 https://reactome.org/PathwayBrowser/#/R-CFA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-444731 https://reactome.org/PathwayBrowser/#/R-CFA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-446195 https://reactome.org/PathwayBrowser/#/R-CFA-446195 DOLK phosphorylates DCHOL to DOLP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-446200 https://reactome.org/PathwayBrowser/#/R-CFA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-446221 https://reactome.org/PathwayBrowser/#/R-CFA-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-446277 https://reactome.org/PathwayBrowser/#/R-CFA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-446277 https://reactome.org/PathwayBrowser/#/R-CFA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-446278 https://reactome.org/PathwayBrowser/#/R-CFA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-446278 https://reactome.org/PathwayBrowser/#/R-CFA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-450971 https://reactome.org/PathwayBrowser/#/R-CFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-469659 https://reactome.org/PathwayBrowser/#/R-CFA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-504054 https://reactome.org/PathwayBrowser/#/R-CFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-508040 https://reactome.org/PathwayBrowser/#/R-CFA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-508308 https://reactome.org/PathwayBrowser/#/R-CFA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-508369 https://reactome.org/PathwayBrowser/#/R-CFA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-508473 https://reactome.org/PathwayBrowser/#/R-CFA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-514604 https://reactome.org/PathwayBrowser/#/R-CFA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5340130 https://reactome.org/PathwayBrowser/#/R-CFA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-5340130 https://reactome.org/PathwayBrowser/#/R-CFA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5362518 https://reactome.org/PathwayBrowser/#/R-CFA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5362522 https://reactome.org/PathwayBrowser/#/R-CFA-5362522 ALDHs oxidise atRAL to atRA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5362564 https://reactome.org/PathwayBrowser/#/R-CFA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5362721 https://reactome.org/PathwayBrowser/#/R-CFA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5419165 https://reactome.org/PathwayBrowser/#/R-CFA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5423637 https://reactome.org/PathwayBrowser/#/R-CFA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-548800 https://reactome.org/PathwayBrowser/#/R-CFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-548814 https://reactome.org/PathwayBrowser/#/R-CFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-548815 https://reactome.org/PathwayBrowser/#/R-CFA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-548818 https://reactome.org/PathwayBrowser/#/R-CFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-548831 https://reactome.org/PathwayBrowser/#/R-CFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-5623643 https://reactome.org/PathwayBrowser/#/R-CFA-5623643 RDH13 reduces atRAL to atROL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5652172 https://reactome.org/PathwayBrowser/#/R-CFA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5652195 https://reactome.org/PathwayBrowser/#/R-CFA-5652195 SORD oxidizes D-sorbitol to Fru IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5661240 https://reactome.org/PathwayBrowser/#/R-CFA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5661256 https://reactome.org/PathwayBrowser/#/R-CFA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5661290 https://reactome.org/PathwayBrowser/#/R-CFA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5662471 https://reactome.org/PathwayBrowser/#/R-CFA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Canis familiaris 15378 R-ALL-5668577 H+ [melanosome lumen] R-CFA-5662662 https://reactome.org/PathwayBrowser/#/R-CFA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-5690042 https://reactome.org/PathwayBrowser/#/R-CFA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-5690046 https://reactome.org/PathwayBrowser/#/R-CFA-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Canis familiaris 15378 R-ALL-428040 H+ [lysosomal lumen] R-CFA-5690517 https://reactome.org/PathwayBrowser/#/R-CFA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5692237 https://reactome.org/PathwayBrowser/#/R-CFA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5692261 https://reactome.org/PathwayBrowser/#/R-CFA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5692283 https://reactome.org/PathwayBrowser/#/R-CFA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-5693148 https://reactome.org/PathwayBrowser/#/R-CFA-5693148 BCKDK phosphorylates BCKDH IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-5693347 https://reactome.org/PathwayBrowser/#/R-CFA-5693347 CRYM reduces P2C to PPCA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5693390 https://reactome.org/PathwayBrowser/#/R-CFA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-5693691 https://reactome.org/PathwayBrowser/#/R-CFA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-5693967 https://reactome.org/PathwayBrowser/#/R-CFA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-5694018 https://reactome.org/PathwayBrowser/#/R-CFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5694462 https://reactome.org/PathwayBrowser/#/R-CFA-5694462 ABHD6,12 hydrolyse 3AG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5696021 https://reactome.org/PathwayBrowser/#/R-CFA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5696080 https://reactome.org/PathwayBrowser/#/R-CFA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-5696091 https://reactome.org/PathwayBrowser/#/R-CFA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5696101 https://reactome.org/PathwayBrowser/#/R-CFA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5696457 https://reactome.org/PathwayBrowser/#/R-CFA-5696457 BDH2 dehydrogenates 3HBA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-5696838 https://reactome.org/PathwayBrowser/#/R-CFA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-597628 https://reactome.org/PathwayBrowser/#/R-CFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6783221 https://reactome.org/PathwayBrowser/#/R-CFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6783939 https://reactome.org/PathwayBrowser/#/R-CFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6783955 https://reactome.org/PathwayBrowser/#/R-CFA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6784224 https://reactome.org/PathwayBrowser/#/R-CFA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6784402 https://reactome.org/PathwayBrowser/#/R-CFA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-6785933 https://reactome.org/PathwayBrowser/#/R-CFA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6786245 https://reactome.org/PathwayBrowser/#/R-CFA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6786720 https://reactome.org/PathwayBrowser/#/R-CFA-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6787642 https://reactome.org/PathwayBrowser/#/R-CFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6787757 https://reactome.org/PathwayBrowser/#/R-CFA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6788611 https://reactome.org/PathwayBrowser/#/R-CFA-6788611 HYKK phosphorylates 5HLYS IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6788999 https://reactome.org/PathwayBrowser/#/R-CFA-6788999 HV1-mediated H+ transfer IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-6788999 https://reactome.org/PathwayBrowser/#/R-CFA-6788999 HV1-mediated H+ transfer IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-6789031 https://reactome.org/PathwayBrowser/#/R-CFA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-6789126 https://reactome.org/PathwayBrowser/#/R-CFA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6793590 https://reactome.org/PathwayBrowser/#/R-CFA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6793591 https://reactome.org/PathwayBrowser/#/R-CFA-6793591 LIAS synthesizes lipoyl-GCSH IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6798317 https://reactome.org/PathwayBrowser/#/R-CFA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6798335 https://reactome.org/PathwayBrowser/#/R-CFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6799495 https://reactome.org/PathwayBrowser/#/R-CFA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6799722 https://reactome.org/PathwayBrowser/#/R-CFA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6801342 https://reactome.org/PathwayBrowser/#/R-CFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6803771 https://reactome.org/PathwayBrowser/#/R-CFA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-6806647 https://reactome.org/PathwayBrowser/#/R-CFA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6806831 https://reactome.org/PathwayBrowser/#/R-CFA-6806831 CYB5Rs reduce MetHb to HbA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6806967 https://reactome.org/PathwayBrowser/#/R-CFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6807055 https://reactome.org/PathwayBrowser/#/R-CFA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6807064 https://reactome.org/PathwayBrowser/#/R-CFA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6807826 https://reactome.org/PathwayBrowser/#/R-CFA-6807826 LDHAL6B reduces PYR to LACT IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6808464 https://reactome.org/PathwayBrowser/#/R-CFA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-6808487 https://reactome.org/PathwayBrowser/#/R-CFA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6808496 https://reactome.org/PathwayBrowser/#/R-CFA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6809264 https://reactome.org/PathwayBrowser/#/R-CFA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6809287 https://reactome.org/PathwayBrowser/#/R-CFA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6809810 https://reactome.org/PathwayBrowser/#/R-CFA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-6810474 https://reactome.org/PathwayBrowser/#/R-CFA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6813749 https://reactome.org/PathwayBrowser/#/R-CFA-6813749 ALDH1A1 oxidises GA to DGA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-6814165 https://reactome.org/PathwayBrowser/#/R-CFA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70286 https://reactome.org/PathwayBrowser/#/R-CFA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70355 https://reactome.org/PathwayBrowser/#/R-CFA-70355 GALK1 phosphorylates Gal to Gal1P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70377 https://reactome.org/PathwayBrowser/#/R-CFA-70377 G6PD multimers dehydrogenate G6P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70420 https://reactome.org/PathwayBrowser/#/R-CFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70449 https://reactome.org/PathwayBrowser/#/R-CFA-70449 GADPH tetramer dehydrogenates GA3P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70467 https://reactome.org/PathwayBrowser/#/R-CFA-70467 PFK tetramer phosphorylates Fru(6)P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70482 https://reactome.org/PathwayBrowser/#/R-CFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70501 https://reactome.org/PathwayBrowser/#/R-CFA-70501 PC carboxylates PYR to OA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70510 https://reactome.org/PathwayBrowser/#/R-CFA-70510 LDH tetramer oxidises LACT to PYR IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70589 https://reactome.org/PathwayBrowser/#/R-CFA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70599 https://reactome.org/PathwayBrowser/#/R-CFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70600 https://reactome.org/PathwayBrowser/#/R-CFA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-70606 https://reactome.org/PathwayBrowser/#/R-CFA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70664 https://reactome.org/PathwayBrowser/#/R-CFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70670 https://reactome.org/PathwayBrowser/#/R-CFA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70679 https://reactome.org/PathwayBrowser/#/R-CFA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70745 https://reactome.org/PathwayBrowser/#/R-CFA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70773 https://reactome.org/PathwayBrowser/#/R-CFA-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70800 https://reactome.org/PathwayBrowser/#/R-CFA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70837 https://reactome.org/PathwayBrowser/#/R-CFA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70859 https://reactome.org/PathwayBrowser/#/R-CFA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70881 https://reactome.org/PathwayBrowser/#/R-CFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70885 https://reactome.org/PathwayBrowser/#/R-CFA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70893 https://reactome.org/PathwayBrowser/#/R-CFA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70938 https://reactome.org/PathwayBrowser/#/R-CFA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70940 https://reactome.org/PathwayBrowser/#/R-CFA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70941 https://reactome.org/PathwayBrowser/#/R-CFA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70975 https://reactome.org/PathwayBrowser/#/R-CFA-70975 CS acetylates OA to citrate IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-70979 https://reactome.org/PathwayBrowser/#/R-CFA-70979 MDH2 dimer dehydrogenates MAL IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-71046 https://reactome.org/PathwayBrowser/#/R-CFA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71130 https://reactome.org/PathwayBrowser/#/R-CFA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71181 https://reactome.org/PathwayBrowser/#/R-CFA-71181 FAH cleaves 4FAA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71217 https://reactome.org/PathwayBrowser/#/R-CFA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71260 https://reactome.org/PathwayBrowser/#/R-CFA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71286 https://reactome.org/PathwayBrowser/#/R-CFA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71296 https://reactome.org/PathwayBrowser/#/R-CFA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-71401 https://reactome.org/PathwayBrowser/#/R-CFA-71401 OGDH dimer decarboxylates 2-OG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71541 https://reactome.org/PathwayBrowser/#/R-CFA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71588 https://reactome.org/PathwayBrowser/#/R-CFA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71670 https://reactome.org/PathwayBrowser/#/R-CFA-71670 PKM dephosphorylates PEP to PYR IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71682 https://reactome.org/PathwayBrowser/#/R-CFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71691 https://reactome.org/PathwayBrowser/#/R-CFA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71707 https://reactome.org/PathwayBrowser/#/R-CFA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-71723 https://reactome.org/PathwayBrowser/#/R-CFA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71802 https://reactome.org/PathwayBrowser/#/R-CFA-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-71849 https://reactome.org/PathwayBrowser/#/R-CFA-71849 LDH tetramer reduces PYR to LACT IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73564 https://reactome.org/PathwayBrowser/#/R-CFA-73564 UMPS dimer decarboxylates OMP to UMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73571 https://reactome.org/PathwayBrowser/#/R-CFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73573 https://reactome.org/PathwayBrowser/#/R-CFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73577 https://reactome.org/PathwayBrowser/#/R-CFA-73577 CAD hexamer transforms L-Gln to CAP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73580 https://reactome.org/PathwayBrowser/#/R-CFA-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73585 https://reactome.org/PathwayBrowser/#/R-CFA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73589 https://reactome.org/PathwayBrowser/#/R-CFA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73591 https://reactome.org/PathwayBrowser/#/R-CFA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73596 https://reactome.org/PathwayBrowser/#/R-CFA-73596 dCMP + H2O => dUMP + NH4+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73616 https://reactome.org/PathwayBrowser/#/R-CFA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73618 https://reactome.org/PathwayBrowser/#/R-CFA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73620 https://reactome.org/PathwayBrowser/#/R-CFA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73647 https://reactome.org/PathwayBrowser/#/R-CFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-73666 https://reactome.org/PathwayBrowser/#/R-CFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73792 https://reactome.org/PathwayBrowser/#/R-CFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73794 https://reactome.org/PathwayBrowser/#/R-CFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73805 https://reactome.org/PathwayBrowser/#/R-CFA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73806 https://reactome.org/PathwayBrowser/#/R-CFA-73806 AIR + CO2 => CAIR IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73810 https://reactome.org/PathwayBrowser/#/R-CFA-73810 FGAM + ATP => AIR + ADP + Pi IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73812 https://reactome.org/PathwayBrowser/#/R-CFA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73813 https://reactome.org/PathwayBrowser/#/R-CFA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-73814 https://reactome.org/PathwayBrowser/#/R-CFA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-73912 https://reactome.org/PathwayBrowser/#/R-CFA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-73920 https://reactome.org/PathwayBrowser/#/R-CFA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-74255 https://reactome.org/PathwayBrowser/#/R-CFA-74255 Guanine + H2O => Xanthine + NH4+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-74723 https://reactome.org/PathwayBrowser/#/R-CFA-74723 Endosome acidification IEA Canis familiaris 15378 R-ALL-74722 H+ [endosome lumen] R-CFA-74723 https://reactome.org/PathwayBrowser/#/R-CFA-74723 Endosome acidification IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-74872 https://reactome.org/PathwayBrowser/#/R-CFA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-749448 https://reactome.org/PathwayBrowser/#/R-CFA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-749452 https://reactome.org/PathwayBrowser/#/R-CFA-749452 The Ligand:GPCR:Gq complex dissociates IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-75851 https://reactome.org/PathwayBrowser/#/R-CFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-75872 https://reactome.org/PathwayBrowser/#/R-CFA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-75883 https://reactome.org/PathwayBrowser/#/R-CFA-75883 DHRS7B reduces GO3P to HXDG3P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-75889 https://reactome.org/PathwayBrowser/#/R-CFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77254 https://reactome.org/PathwayBrowser/#/R-CFA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77283 https://reactome.org/PathwayBrowser/#/R-CFA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77303 https://reactome.org/PathwayBrowser/#/R-CFA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77312 https://reactome.org/PathwayBrowser/#/R-CFA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77323 https://reactome.org/PathwayBrowser/#/R-CFA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77331 https://reactome.org/PathwayBrowser/#/R-CFA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-77342 https://reactome.org/PathwayBrowser/#/R-CFA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-804969 https://reactome.org/PathwayBrowser/#/R-CFA-804969 HSD17B1 hydrogenates E1 to EST17b IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8850846 https://reactome.org/PathwayBrowser/#/R-CFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8850854 https://reactome.org/PathwayBrowser/#/R-CFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851089 https://reactome.org/PathwayBrowser/#/R-CFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851110 https://reactome.org/PathwayBrowser/#/R-CFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851129 https://reactome.org/PathwayBrowser/#/R-CFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-8851225 https://reactome.org/PathwayBrowser/#/R-CFA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-8851234 https://reactome.org/PathwayBrowser/#/R-CFA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851356 https://reactome.org/PathwayBrowser/#/R-CFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851396 https://reactome.org/PathwayBrowser/#/R-CFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-CFA-8851494 https://reactome.org/PathwayBrowser/#/R-CFA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851538 https://reactome.org/PathwayBrowser/#/R-CFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8851550 https://reactome.org/PathwayBrowser/#/R-CFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-8856223 https://reactome.org/PathwayBrowser/#/R-CFA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8862137 https://reactome.org/PathwayBrowser/#/R-CFA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-8862152 https://reactome.org/PathwayBrowser/#/R-CFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8863494 https://reactome.org/PathwayBrowser/#/R-CFA-8863494 ASICs bind STOML3, (STOM) IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-8863761 https://reactome.org/PathwayBrowser/#/R-CFA-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-8866601 https://reactome.org/PathwayBrowser/#/R-CFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8869606 https://reactome.org/PathwayBrowser/#/R-CFA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8869633 https://reactome.org/PathwayBrowser/#/R-CFA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8870346 https://reactome.org/PathwayBrowser/#/R-CFA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8875623 https://reactome.org/PathwayBrowser/#/R-CFA-8875623 SLC25A18,22 import L-Glu, H+ IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-8875623 https://reactome.org/PathwayBrowser/#/R-CFA-8875623 SLC25A18,22 import L-Glu, H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8876789 https://reactome.org/PathwayBrowser/#/R-CFA-8876789 CARNMT1 methylates CARN to Anserine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8876889 https://reactome.org/PathwayBrowser/#/R-CFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-8878914 https://reactome.org/PathwayBrowser/#/R-CFA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-888548 https://reactome.org/PathwayBrowser/#/R-CFA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-888572 https://reactome.org/PathwayBrowser/#/R-CFA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-888577 https://reactome.org/PathwayBrowser/#/R-CFA-888577 Synthesis of GABA by GAD2 IEA Canis familiaris 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-CFA-8933635 https://reactome.org/PathwayBrowser/#/R-CFA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8936442 https://reactome.org/PathwayBrowser/#/R-CFA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8938076 https://reactome.org/PathwayBrowser/#/R-CFA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8939959 https://reactome.org/PathwayBrowser/#/R-CFA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8940070 https://reactome.org/PathwayBrowser/#/R-CFA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8942575 https://reactome.org/PathwayBrowser/#/R-CFA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-8952873 https://reactome.org/PathwayBrowser/#/R-CFA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-8954468 https://reactome.org/PathwayBrowser/#/R-CFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-8955030 https://reactome.org/PathwayBrowser/#/R-CFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8955760 https://reactome.org/PathwayBrowser/#/R-CFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8955844 https://reactome.org/PathwayBrowser/#/R-CFA-8955844 RBKS phosphorylates ribose to R5P IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8959510 https://reactome.org/PathwayBrowser/#/R-CFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-8959719 https://reactome.org/PathwayBrowser/#/R-CFA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9009950 https://reactome.org/PathwayBrowser/#/R-CFA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9011595 https://reactome.org/PathwayBrowser/#/R-CFA-9011595 GSTZ1 dimer dehalogenates DCA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9012016 https://reactome.org/PathwayBrowser/#/R-CFA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9012036 https://reactome.org/PathwayBrowser/#/R-CFA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-9013198 https://reactome.org/PathwayBrowser/#/R-CFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9024766 https://reactome.org/PathwayBrowser/#/R-CFA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15378 R-ALL-74722 H+ [endosome lumen] R-CFA-917811 https://reactome.org/PathwayBrowser/#/R-CFA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 15378 R-ALL-74722 H+ [endosome lumen] R-CFA-917841 https://reactome.org/PathwayBrowser/#/R-CFA-917841 Acidification of Tf:TfR1 containing endosome IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-917979 https://reactome.org/PathwayBrowser/#/R-CFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-937311 https://reactome.org/PathwayBrowser/#/R-CFA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9619024 https://reactome.org/PathwayBrowser/#/R-CFA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-9645220 https://reactome.org/PathwayBrowser/#/R-CFA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-9650165 https://reactome.org/PathwayBrowser/#/R-CFA-9650165 ASIC trimers bind H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9695949 https://reactome.org/PathwayBrowser/#/R-CFA-9695949 SPHK2 phosphorylates sphingoid IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9705713 https://reactome.org/PathwayBrowser/#/R-CFA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9705714 https://reactome.org/PathwayBrowser/#/R-CFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9709098 https://reactome.org/PathwayBrowser/#/R-CFA-9709098 DHFR dimer reduces FOLA to DHF IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-9727198 https://reactome.org/PathwayBrowser/#/R-CFA-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9727347 https://reactome.org/PathwayBrowser/#/R-CFA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9727349 https://reactome.org/PathwayBrowser/#/R-CFA-9727349 XDH dehydrogenates xanthine to form urate IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9731228 https://reactome.org/PathwayBrowser/#/R-CFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9731590 https://reactome.org/PathwayBrowser/#/R-CFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9731613 https://reactome.org/PathwayBrowser/#/R-CFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9731632 https://reactome.org/PathwayBrowser/#/R-CFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9731661 https://reactome.org/PathwayBrowser/#/R-CFA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9748945 https://reactome.org/PathwayBrowser/#/R-CFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9748957 https://reactome.org/PathwayBrowser/#/R-CFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9748979 https://reactome.org/PathwayBrowser/#/R-CFA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9748983 https://reactome.org/PathwayBrowser/#/R-CFA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9748991 https://reactome.org/PathwayBrowser/#/R-CFA-9748991 XDH oxidises 6MP to 6TU IEA Canis familiaris 15378 R-ALL-351626 H+ [extracellular region] R-CFA-9749609 https://reactome.org/PathwayBrowser/#/R-CFA-9749609 BCHE hydrolyzes ASA- IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9749647 https://reactome.org/PathwayBrowser/#/R-CFA-9749647 CES2 hydrolyzes ASA- IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9749792 https://reactome.org/PathwayBrowser/#/R-CFA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9755937 https://reactome.org/PathwayBrowser/#/R-CFA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9756177 https://reactome.org/PathwayBrowser/#/R-CFA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9757706 https://reactome.org/PathwayBrowser/#/R-CFA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9758661 https://reactome.org/PathwayBrowser/#/R-CFA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9759259 https://reactome.org/PathwayBrowser/#/R-CFA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9759549 https://reactome.org/PathwayBrowser/#/R-CFA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9760094 https://reactome.org/PathwayBrowser/#/R-CFA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-977301 https://reactome.org/PathwayBrowser/#/R-CFA-977301 Histidine is decarboxylated to histamine IEA Canis familiaris 15378 R-ALL-193465 H+ [peroxisomal matrix] R-CFA-977317 https://reactome.org/PathwayBrowser/#/R-CFA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-977348 https://reactome.org/PathwayBrowser/#/R-CFA-977348 PHGDH tetramer dehydrogenates 3PG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9773976 https://reactome.org/PathwayBrowser/#/R-CFA-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9794270 https://reactome.org/PathwayBrowser/#/R-CFA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Canis familiaris 15378 R-ALL-9668967 H+ [nucleoplasm] R-CFA-9825790 https://reactome.org/PathwayBrowser/#/R-CFA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9837337 https://reactome.org/PathwayBrowser/#/R-CFA-9837337 DCAKD phosphorylates DP-CoA IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9843721 https://reactome.org/PathwayBrowser/#/R-CFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9844860 https://reactome.org/PathwayBrowser/#/R-CFA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9845516 https://reactome.org/PathwayBrowser/#/R-CFA-9845516 B3GALT4 transfers Gal to gangliosides IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9845538 https://reactome.org/PathwayBrowser/#/R-CFA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9845587 https://reactome.org/PathwayBrowser/#/R-CFA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9846305 https://reactome.org/PathwayBrowser/#/R-CFA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9846332 https://reactome.org/PathwayBrowser/#/R-CFA-9846332 FUT1,2 transfer fucose to gangliosides IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9846477 https://reactome.org/PathwayBrowser/#/R-CFA-9846477 A4GALT transfers galactose to LacCer IEA Canis familiaris 15378 R-ALL-425969 H+ [Golgi lumen] R-CFA-9851347 https://reactome.org/PathwayBrowser/#/R-CFA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9853499 https://reactome.org/PathwayBrowser/#/R-CFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9854315 https://reactome.org/PathwayBrowser/#/R-CFA-9854315 CSKMT methylates Citrate Synthase IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9854415 https://reactome.org/PathwayBrowser/#/R-CFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9856871 https://reactome.org/PathwayBrowser/#/R-CFA-9856871 MDH1 reduces OA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9858321 https://reactome.org/PathwayBrowser/#/R-CFA-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9858589 https://reactome.org/PathwayBrowser/#/R-CFA-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9858590 https://reactome.org/PathwayBrowser/#/R-CFA-9858590 DLST transfers glutaryl to CoA IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9859148 https://reactome.org/PathwayBrowser/#/R-CFA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9859172 https://reactome.org/PathwayBrowser/#/R-CFA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9861616 https://reactome.org/PathwayBrowser/#/R-CFA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9861642 https://reactome.org/PathwayBrowser/#/R-CFA-9861642 NEK1 phosphorylates ME1 IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9861660 https://reactome.org/PathwayBrowser/#/R-CFA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9861734 https://reactome.org/PathwayBrowser/#/R-CFA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9864415 https://reactome.org/PathwayBrowser/#/R-CFA-9864415 AAC1 imports a proton IEA Canis familiaris 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-CFA-9864415 https://reactome.org/PathwayBrowser/#/R-CFA-9864415 AAC1 imports a proton IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9909159 https://reactome.org/PathwayBrowser/#/R-CFA-9909159 HK1 phosphorylates Mannose to Man6P IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9915971 https://reactome.org/PathwayBrowser/#/R-CFA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9915993 https://reactome.org/PathwayBrowser/#/R-CFA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9915997 https://reactome.org/PathwayBrowser/#/R-CFA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Canis familiaris 15378 R-ALL-113529 H+ [mitochondrial matrix] R-CFA-9929439 https://reactome.org/PathwayBrowser/#/R-CFA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9935449 https://reactome.org/PathwayBrowser/#/R-CFA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Canis familiaris 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-CFA-9935469 https://reactome.org/PathwayBrowser/#/R-CFA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9937295 https://reactome.org/PathwayBrowser/#/R-CFA-9937295 SRD5A3 reduces polyprenal to dolichal IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9937298 https://reactome.org/PathwayBrowser/#/R-CFA-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-CFA-9937340 https://reactome.org/PathwayBrowser/#/R-CFA-9937340 DHRSX reduces dolichal to dolichol IEA Canis familiaris 15378 R-ALL-70106 H+ [cytosol] R-DDI-111215 https://reactome.org/PathwayBrowser/#/R-DDI-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-111524 https://reactome.org/PathwayBrowser/#/R-DDI-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1222516 https://reactome.org/PathwayBrowser/#/R-DDI-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Dictyostelium discoideum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DDI-1222516 https://reactome.org/PathwayBrowser/#/R-DDI-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1497869 https://reactome.org/PathwayBrowser/#/R-DDI-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15378 R-ALL-428040 H+ [lysosomal lumen] R-DDI-1605797 https://reactome.org/PathwayBrowser/#/R-DDI-1605797 SMPD1 hydrolyzes SPHM IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1606273 https://reactome.org/PathwayBrowser/#/R-DDI-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1614567 https://reactome.org/PathwayBrowser/#/R-DDI-1614567 Excess homocysteine yields homolanthionine and H2S IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1614591 https://reactome.org/PathwayBrowser/#/R-DDI-1614591 Excess cysteine yields lanthionine and H2S IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1614614 https://reactome.org/PathwayBrowser/#/R-DDI-1614614 Cysteine is degraded to pyruvate and H2S IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1614631 https://reactome.org/PathwayBrowser/#/R-DDI-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1640164 https://reactome.org/PathwayBrowser/#/R-DDI-1640164 ENPP7 hydrolyzes sphingomyelin IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-164651 https://reactome.org/PathwayBrowser/#/R-DDI-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-169270 https://reactome.org/PathwayBrowser/#/R-DDI-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-189425 https://reactome.org/PathwayBrowser/#/R-DDI-189425 UROD decarboxylates URO3 to COPRO3 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-189439 https://reactome.org/PathwayBrowser/#/R-DDI-189439 ALAD condenses 2 dALAs to form PBG IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-189442 https://reactome.org/PathwayBrowser/#/R-DDI-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-189465 https://reactome.org/PathwayBrowser/#/R-DDI-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-190182 https://reactome.org/PathwayBrowser/#/R-DDI-190182 UROD decarboxylates URO1 to COPRO1 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-191323 https://reactome.org/PathwayBrowser/#/R-DDI-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-191352 https://reactome.org/PathwayBrowser/#/R-DDI-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-191402 https://reactome.org/PathwayBrowser/#/R-DDI-191402 Reduction of presqualene diphosphate to form squalene IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-192033 https://reactome.org/PathwayBrowser/#/R-DDI-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-192036 https://reactome.org/PathwayBrowser/#/R-DDI-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-192067 https://reactome.org/PathwayBrowser/#/R-DDI-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-192160 https://reactome.org/PathwayBrowser/#/R-DDI-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193064 https://reactome.org/PathwayBrowser/#/R-DDI-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-193455 https://reactome.org/PathwayBrowser/#/R-DDI-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-193508 https://reactome.org/PathwayBrowser/#/R-DDI-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193746 https://reactome.org/PathwayBrowser/#/R-DDI-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193755 https://reactome.org/PathwayBrowser/#/R-DDI-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193758 https://reactome.org/PathwayBrowser/#/R-DDI-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193781 https://reactome.org/PathwayBrowser/#/R-DDI-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193800 https://reactome.org/PathwayBrowser/#/R-DDI-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193821 https://reactome.org/PathwayBrowser/#/R-DDI-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193824 https://reactome.org/PathwayBrowser/#/R-DDI-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193841 https://reactome.org/PathwayBrowser/#/R-DDI-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194642 https://reactome.org/PathwayBrowser/#/R-DDI-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15378 R-ALL-194688 H+ [nuclear envelope] R-DDI-194674 https://reactome.org/PathwayBrowser/#/R-DDI-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194698 https://reactome.org/PathwayBrowser/#/R-DDI-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-194718 https://reactome.org/PathwayBrowser/#/R-DDI-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196060 https://reactome.org/PathwayBrowser/#/R-DDI-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196753 https://reactome.org/PathwayBrowser/#/R-DDI-196753 2xPPCS ligates PPanK with Cys IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196754 https://reactome.org/PathwayBrowser/#/R-DDI-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196773 https://reactome.org/PathwayBrowser/#/R-DDI-196773 COASY phosphorylates DP-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196840 https://reactome.org/PathwayBrowser/#/R-DDI-196840 3xPPCDC:3FMN decarboxylates PPC IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196929 https://reactome.org/PathwayBrowser/#/R-DDI-196929 FLAD1 phosphorylates FMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-196955 https://reactome.org/PathwayBrowser/#/R-DDI-196955 2xENPP1 hydrolyzes FAD to FMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197198 https://reactome.org/PathwayBrowser/#/R-DDI-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197235 https://reactome.org/PathwayBrowser/#/R-DDI-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197268 https://reactome.org/PathwayBrowser/#/R-DDI-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197271 https://reactome.org/PathwayBrowser/#/R-DDI-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197963 https://reactome.org/PathwayBrowser/#/R-DDI-197963 DHFR2 reduces FOLA to DHF IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-197972 https://reactome.org/PathwayBrowser/#/R-DDI-197972 DHF is reduced to tetrahydrofolate (THF) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-198824 https://reactome.org/PathwayBrowser/#/R-DDI-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-200423 https://reactome.org/PathwayBrowser/#/R-DDI-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-200474 https://reactome.org/PathwayBrowser/#/R-DDI-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15378 R-ALL-9668967 H+ [nucleoplasm] R-DDI-200512 https://reactome.org/PathwayBrowser/#/R-DDI-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-200555 https://reactome.org/PathwayBrowser/#/R-DDI-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-200644 https://reactome.org/PathwayBrowser/#/R-DDI-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-200676 https://reactome.org/PathwayBrowser/#/R-DDI-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-200718 https://reactome.org/PathwayBrowser/#/R-DDI-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-202111 https://reactome.org/PathwayBrowser/#/R-DDI-202111 AKT1 phosphorylates eNOS IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-203613 https://reactome.org/PathwayBrowser/#/R-DDI-203613 Depalmitoylation of eNOS IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-204617 https://reactome.org/PathwayBrowser/#/R-DDI-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-204647 https://reactome.org/PathwayBrowser/#/R-DDI-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-209772 https://reactome.org/PathwayBrowser/#/R-DDI-209772 Thyroxine is deiodinated to triiodothyronine IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-209821 https://reactome.org/PathwayBrowser/#/R-DDI-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-209973 https://reactome.org/PathwayBrowser/#/R-DDI-209973 Tyrosine is diiodinated IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2161549 https://reactome.org/PathwayBrowser/#/R-DDI-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2161614 https://reactome.org/PathwayBrowser/#/R-DDI-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2162078 https://reactome.org/PathwayBrowser/#/R-DDI-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162186 https://reactome.org/PathwayBrowser/#/R-DDI-2162186 COQ3 methylates DeMQ10H2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162187 https://reactome.org/PathwayBrowser/#/R-DDI-2162187 COQ6 hydroxylates DHB IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162188 https://reactome.org/PathwayBrowser/#/R-DDI-2162188 COQ5 methylates MDMQ10H2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162193 https://reactome.org/PathwayBrowser/#/R-DDI-2162193 COQ3 methylates DHDB IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2162195 https://reactome.org/PathwayBrowser/#/R-DDI-2162195 COQ4 decarboxylates MHDB IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2395512 https://reactome.org/PathwayBrowser/#/R-DDI-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-2395517 https://reactome.org/PathwayBrowser/#/R-DDI-2395517 NADPH transfers electrons to FDXR IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2509827 https://reactome.org/PathwayBrowser/#/R-DDI-2509827 ITPA hydrolyses ITP to IMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2509831 https://reactome.org/PathwayBrowser/#/R-DDI-2509831 ITPA hydrolyses XTP to XMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2509838 https://reactome.org/PathwayBrowser/#/R-DDI-2509838 ITPA hydrolyses dITP to dIMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-266070 https://reactome.org/PathwayBrowser/#/R-DDI-266070 LTC4 is exported from the cytosol by ABCC1 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-2730692 https://reactome.org/PathwayBrowser/#/R-DDI-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Dictyostelium discoideum 15378 R-ALL-74722 H+ [endosome lumen] R-DDI-2730692 https://reactome.org/PathwayBrowser/#/R-DDI-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3095889 https://reactome.org/PathwayBrowser/#/R-DDI-3095889 MMACHC dealkylates RCbl IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3149518 https://reactome.org/PathwayBrowser/#/R-DDI-3149518 MTRR reduces cob(II)alamin to meCbl IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3149519 https://reactome.org/PathwayBrowser/#/R-DDI-3149519 MMACHC decyanates CNCbl IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-3159253 https://reactome.org/PathwayBrowser/#/R-DDI-3159253 MMAB adenosylates cob(I)alamin IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322001 https://reactome.org/PathwayBrowser/#/R-DDI-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322003 https://reactome.org/PathwayBrowser/#/R-DDI-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322009 https://reactome.org/PathwayBrowser/#/R-DDI-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322014 https://reactome.org/PathwayBrowser/#/R-DDI-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322019 https://reactome.org/PathwayBrowser/#/R-DDI-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322025 https://reactome.org/PathwayBrowser/#/R-DDI-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-3322041 https://reactome.org/PathwayBrowser/#/R-DDI-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-3323079 https://reactome.org/PathwayBrowser/#/R-DDI-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-350869 https://reactome.org/PathwayBrowser/#/R-DDI-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-350901 https://reactome.org/PathwayBrowser/#/R-DDI-350901 Iodide is organified IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-372448 https://reactome.org/PathwayBrowser/#/R-DDI-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-375405 https://reactome.org/PathwayBrowser/#/R-DDI-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-375405 https://reactome.org/PathwayBrowser/#/R-DDI-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-375417 https://reactome.org/PathwayBrowser/#/R-DDI-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-380608 https://reactome.org/PathwayBrowser/#/R-DDI-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-389540 https://reactome.org/PathwayBrowser/#/R-DDI-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-389550 https://reactome.org/PathwayBrowser/#/R-DDI-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-389609 https://reactome.org/PathwayBrowser/#/R-DDI-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-389995 https://reactome.org/PathwayBrowser/#/R-DDI-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-390251 https://reactome.org/PathwayBrowser/#/R-DDI-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-390393 https://reactome.org/PathwayBrowser/#/R-DDI-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-390425 https://reactome.org/PathwayBrowser/#/R-DDI-390425 FAR1 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-390438 https://reactome.org/PathwayBrowser/#/R-DDI-390438 FAR2 reduces PalmCoA to HXOL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-425965 https://reactome.org/PathwayBrowser/#/R-DDI-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Dictyostelium discoideum 15378 R-ALL-425999 H+ [late endosome lumen] R-DDI-425965 https://reactome.org/PathwayBrowser/#/R-DDI-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-425983 https://reactome.org/PathwayBrowser/#/R-DDI-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Dictyostelium discoideum 15378 R-ALL-425978 H+ [early endosome lumen] R-DDI-425983 https://reactome.org/PathwayBrowser/#/R-DDI-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-425994 https://reactome.org/PathwayBrowser/#/R-DDI-425994 Na+/H+ exchanger transport (at cell membrane) IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-425994 https://reactome.org/PathwayBrowser/#/R-DDI-425994 Na+/H+ exchanger transport (at cell membrane) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-426015 https://reactome.org/PathwayBrowser/#/R-DDI-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Dictyostelium discoideum 15378 R-ALL-425969 H+ [Golgi lumen] R-DDI-426015 https://reactome.org/PathwayBrowser/#/R-DDI-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-426043 https://reactome.org/PathwayBrowser/#/R-DDI-426043 2-AG hydrolysis to arachidonate by MAGL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-427555 https://reactome.org/PathwayBrowser/#/R-DDI-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-427555 https://reactome.org/PathwayBrowser/#/R-DDI-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-427998 https://reactome.org/PathwayBrowser/#/R-DDI-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428052 https://reactome.org/PathwayBrowser/#/R-DDI-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Dictyostelium discoideum 15378 R-ALL-428548 H+ [synaptic vesicle] R-DDI-428052 https://reactome.org/PathwayBrowser/#/R-DDI-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428123 https://reactome.org/PathwayBrowser/#/R-DDI-428123 KDSR reduces 3-ketosphingoid IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428185 https://reactome.org/PathwayBrowser/#/R-DDI-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428273 https://reactome.org/PathwayBrowser/#/R-DDI-428273 SPHK1 phosphorylates sphingoid IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-428585 https://reactome.org/PathwayBrowser/#/R-DDI-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-ALL-428040 H+ [lysosomal lumen] R-DDI-428585 https://reactome.org/PathwayBrowser/#/R-DDI-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-429101 https://reactome.org/PathwayBrowser/#/R-DDI-429101 HMIT co-transports myo-inositol with a proton IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-429101 https://reactome.org/PathwayBrowser/#/R-DDI-429101 HMIT co-transports myo-inositol with a proton IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-429157 https://reactome.org/PathwayBrowser/#/R-DDI-429157 ABCC4 accumulation of dense granule contents IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-434650 https://reactome.org/PathwayBrowser/#/R-DDI-434650 MATEs mediate extrusion of xenobiotics IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DDI-435171 https://reactome.org/PathwayBrowser/#/R-DDI-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-435349 https://reactome.org/PathwayBrowser/#/R-DDI-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-435349 https://reactome.org/PathwayBrowser/#/R-DDI-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-444393 https://reactome.org/PathwayBrowser/#/R-DDI-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-444393 https://reactome.org/PathwayBrowser/#/R-DDI-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-444419 https://reactome.org/PathwayBrowser/#/R-DDI-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-444419 https://reactome.org/PathwayBrowser/#/R-DDI-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-446195 https://reactome.org/PathwayBrowser/#/R-DDI-446195 DOLK phosphorylates DCHOL to DOLP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-446200 https://reactome.org/PathwayBrowser/#/R-DDI-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-446221 https://reactome.org/PathwayBrowser/#/R-DDI-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-446277 https://reactome.org/PathwayBrowser/#/R-DDI-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-446277 https://reactome.org/PathwayBrowser/#/R-DDI-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-446278 https://reactome.org/PathwayBrowser/#/R-DDI-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-446278 https://reactome.org/PathwayBrowser/#/R-DDI-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-450971 https://reactome.org/PathwayBrowser/#/R-DDI-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-504054 https://reactome.org/PathwayBrowser/#/R-DDI-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-508308 https://reactome.org/PathwayBrowser/#/R-DDI-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-508369 https://reactome.org/PathwayBrowser/#/R-DDI-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-508473 https://reactome.org/PathwayBrowser/#/R-DDI-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5340130 https://reactome.org/PathwayBrowser/#/R-DDI-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-ALL-428040 H+ [lysosomal lumen] R-DDI-5340130 https://reactome.org/PathwayBrowser/#/R-DDI-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5362522 https://reactome.org/PathwayBrowser/#/R-DDI-5362522 ALDHs oxidise atRAL to atRA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5362564 https://reactome.org/PathwayBrowser/#/R-DDI-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5419165 https://reactome.org/PathwayBrowser/#/R-DDI-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-548800 https://reactome.org/PathwayBrowser/#/R-DDI-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-548814 https://reactome.org/PathwayBrowser/#/R-DDI-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-548818 https://reactome.org/PathwayBrowser/#/R-DDI-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-548831 https://reactome.org/PathwayBrowser/#/R-DDI-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5615668 https://reactome.org/PathwayBrowser/#/R-DDI-5615668 AKR1C3 reduces atRAL to atROL IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-5623643 https://reactome.org/PathwayBrowser/#/R-DDI-5623643 RDH13 reduces atRAL to atROL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5652172 https://reactome.org/PathwayBrowser/#/R-DDI-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5661256 https://reactome.org/PathwayBrowser/#/R-DDI-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Dictyostelium discoideum 15378 R-ALL-5668577 H+ [melanosome lumen] R-DDI-5662662 https://reactome.org/PathwayBrowser/#/R-DDI-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15378 R-ALL-428040 H+ [lysosomal lumen] R-DDI-5690046 https://reactome.org/PathwayBrowser/#/R-DDI-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Dictyostelium discoideum 15378 R-ALL-428040 H+ [lysosomal lumen] R-DDI-5690517 https://reactome.org/PathwayBrowser/#/R-DDI-5690517 PPT1 hydrolyses palmitoylated proteins IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5692237 https://reactome.org/PathwayBrowser/#/R-DDI-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5692261 https://reactome.org/PathwayBrowser/#/R-DDI-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5692283 https://reactome.org/PathwayBrowser/#/R-DDI-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-5693347 https://reactome.org/PathwayBrowser/#/R-DDI-5693347 CRYM reduces P2C to PPCA IEA Dictyostelium discoideum 15378 R-ALL-351626 H+ [extracellular region] R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-5693691 https://reactome.org/PathwayBrowser/#/R-DDI-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-5693967 https://reactome.org/PathwayBrowser/#/R-DDI-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-5694018 https://reactome.org/PathwayBrowser/#/R-DDI-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5696021 https://reactome.org/PathwayBrowser/#/R-DDI-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5696080 https://reactome.org/PathwayBrowser/#/R-DDI-5696080 ALDH3B1 oxidises HXAL to PALM IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-5696091 https://reactome.org/PathwayBrowser/#/R-DDI-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-5696101 https://reactome.org/PathwayBrowser/#/R-DDI-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-5696822 https://reactome.org/PathwayBrowser/#/R-DDI-5696822 AKR1B15 reduces EST17b to E1 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6783221 https://reactome.org/PathwayBrowser/#/R-DDI-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6783939 https://reactome.org/PathwayBrowser/#/R-DDI-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6783955 https://reactome.org/PathwayBrowser/#/R-DDI-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-6784224 https://reactome.org/PathwayBrowser/#/R-DDI-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6787642 https://reactome.org/PathwayBrowser/#/R-DDI-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Dictyostelium discoideum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DDI-6789031 https://reactome.org/PathwayBrowser/#/R-DDI-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DDI-6789126 https://reactome.org/PathwayBrowser/#/R-DDI-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-6793590 https://reactome.org/PathwayBrowser/#/R-DDI-6793590 LIPT2 transfers octanoyl group to GCSH IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6798335 https://reactome.org/PathwayBrowser/#/R-DDI-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6799722 https://reactome.org/PathwayBrowser/#/R-DDI-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-6806967 https://reactome.org/PathwayBrowser/#/R-DDI-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6808464 https://reactome.org/PathwayBrowser/#/R-DDI-6808464 ALDH3B2 oxidises HXAL to PALM IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-6809287 https://reactome.org/PathwayBrowser/#/R-DDI-6809287 NUDT12 hydrolyses NADH to NMNH IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-6810474 https://reactome.org/PathwayBrowser/#/R-DDI-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6813749 https://reactome.org/PathwayBrowser/#/R-DDI-6813749 ALDH1A1 oxidises GA to DGA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70286 https://reactome.org/PathwayBrowser/#/R-DDI-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70333 https://reactome.org/PathwayBrowser/#/R-DDI-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70377 https://reactome.org/PathwayBrowser/#/R-DDI-70377 G6PD multimers dehydrogenate G6P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70449 https://reactome.org/PathwayBrowser/#/R-DDI-70449 GADPH tetramer dehydrogenates GA3P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70482 https://reactome.org/PathwayBrowser/#/R-DDI-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70589 https://reactome.org/PathwayBrowser/#/R-DDI-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-70599 https://reactome.org/PathwayBrowser/#/R-DDI-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70600 https://reactome.org/PathwayBrowser/#/R-DDI-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70664 https://reactome.org/PathwayBrowser/#/R-DDI-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70670 https://reactome.org/PathwayBrowser/#/R-DDI-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70745 https://reactome.org/PathwayBrowser/#/R-DDI-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70773 https://reactome.org/PathwayBrowser/#/R-DDI-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70800 https://reactome.org/PathwayBrowser/#/R-DDI-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70837 https://reactome.org/PathwayBrowser/#/R-DDI-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70859 https://reactome.org/PathwayBrowser/#/R-DDI-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70881 https://reactome.org/PathwayBrowser/#/R-DDI-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70885 https://reactome.org/PathwayBrowser/#/R-DDI-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70893 https://reactome.org/PathwayBrowser/#/R-DDI-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70938 https://reactome.org/PathwayBrowser/#/R-DDI-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70940 https://reactome.org/PathwayBrowser/#/R-DDI-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70941 https://reactome.org/PathwayBrowser/#/R-DDI-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-70975 https://reactome.org/PathwayBrowser/#/R-DDI-70975 CS acetylates OA to citrate IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-71046 https://reactome.org/PathwayBrowser/#/R-DDI-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71130 https://reactome.org/PathwayBrowser/#/R-DDI-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71181 https://reactome.org/PathwayBrowser/#/R-DDI-71181 FAH cleaves 4FAA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71217 https://reactome.org/PathwayBrowser/#/R-DDI-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71296 https://reactome.org/PathwayBrowser/#/R-DDI-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-71401 https://reactome.org/PathwayBrowser/#/R-DDI-71401 OGDH dimer decarboxylates 2-OG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71670 https://reactome.org/PathwayBrowser/#/R-DDI-71670 PKM dephosphorylates PEP to PYR IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71682 https://reactome.org/PathwayBrowser/#/R-DDI-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71691 https://reactome.org/PathwayBrowser/#/R-DDI-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71707 https://reactome.org/PathwayBrowser/#/R-DDI-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-71723 https://reactome.org/PathwayBrowser/#/R-DDI-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-71802 https://reactome.org/PathwayBrowser/#/R-DDI-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73564 https://reactome.org/PathwayBrowser/#/R-DDI-73564 UMPS dimer decarboxylates OMP to UMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73571 https://reactome.org/PathwayBrowser/#/R-DDI-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73573 https://reactome.org/PathwayBrowser/#/R-DDI-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73577 https://reactome.org/PathwayBrowser/#/R-DDI-73577 CAD hexamer transforms L-Gln to CAP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73580 https://reactome.org/PathwayBrowser/#/R-DDI-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73585 https://reactome.org/PathwayBrowser/#/R-DDI-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73589 https://reactome.org/PathwayBrowser/#/R-DDI-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73591 https://reactome.org/PathwayBrowser/#/R-DDI-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73616 https://reactome.org/PathwayBrowser/#/R-DDI-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73618 https://reactome.org/PathwayBrowser/#/R-DDI-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73620 https://reactome.org/PathwayBrowser/#/R-DDI-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73647 https://reactome.org/PathwayBrowser/#/R-DDI-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Dictyostelium discoideum 15378 R-ALL-9668967 H+ [nucleoplasm] R-DDI-73666 https://reactome.org/PathwayBrowser/#/R-DDI-73666 dUTP + H2O => dUMP + pyrophosphate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73792 https://reactome.org/PathwayBrowser/#/R-DDI-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73794 https://reactome.org/PathwayBrowser/#/R-DDI-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73810 https://reactome.org/PathwayBrowser/#/R-DDI-73810 FGAM + ATP => AIR + ADP + Pi IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73812 https://reactome.org/PathwayBrowser/#/R-DDI-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73813 https://reactome.org/PathwayBrowser/#/R-DDI-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-73814 https://reactome.org/PathwayBrowser/#/R-DDI-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-74255 https://reactome.org/PathwayBrowser/#/R-DDI-74255 Guanine + H2O => Xanthine + NH4+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-74723 https://reactome.org/PathwayBrowser/#/R-DDI-74723 Endosome acidification IEA Dictyostelium discoideum 15378 R-ALL-74722 H+ [endosome lumen] R-DDI-74723 https://reactome.org/PathwayBrowser/#/R-DDI-74723 Endosome acidification IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-75851 https://reactome.org/PathwayBrowser/#/R-DDI-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-75872 https://reactome.org/PathwayBrowser/#/R-DDI-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-804969 https://reactome.org/PathwayBrowser/#/R-DDI-804969 HSD17B1 hydrogenates E1 to EST17b IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-8862152 https://reactome.org/PathwayBrowser/#/R-DDI-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Dictyostelium discoideum 15378 R-ALL-9668967 H+ [nucleoplasm] R-DDI-8866601 https://reactome.org/PathwayBrowser/#/R-DDI-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8869606 https://reactome.org/PathwayBrowser/#/R-DDI-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8869607 https://reactome.org/PathwayBrowser/#/R-DDI-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8869627 https://reactome.org/PathwayBrowser/#/R-DDI-8869627 NMRK2 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8869633 https://reactome.org/PathwayBrowser/#/R-DDI-8869633 NMRK1 phosphorylates NR to yield NMN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8875623 https://reactome.org/PathwayBrowser/#/R-DDI-8875623 SLC25A18,22 import L-Glu, H+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-8875623 https://reactome.org/PathwayBrowser/#/R-DDI-8875623 SLC25A18,22 import L-Glu, H+ IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8876789 https://reactome.org/PathwayBrowser/#/R-DDI-8876789 CARNMT1 methylates CARN to Anserine IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8876889 https://reactome.org/PathwayBrowser/#/R-DDI-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Dictyostelium discoideum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DDI-8933635 https://reactome.org/PathwayBrowser/#/R-DDI-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8936442 https://reactome.org/PathwayBrowser/#/R-DDI-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8939959 https://reactome.org/PathwayBrowser/#/R-DDI-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-8952873 https://reactome.org/PathwayBrowser/#/R-DDI-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-8954468 https://reactome.org/PathwayBrowser/#/R-DDI-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8955760 https://reactome.org/PathwayBrowser/#/R-DDI-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8955844 https://reactome.org/PathwayBrowser/#/R-DDI-8955844 RBKS phosphorylates ribose to R5P IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-8959510 https://reactome.org/PathwayBrowser/#/R-DDI-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9011595 https://reactome.org/PathwayBrowser/#/R-DDI-9011595 GSTZ1 dimer dehalogenates DCA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9012016 https://reactome.org/PathwayBrowser/#/R-DDI-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-9013198 https://reactome.org/PathwayBrowser/#/R-DDI-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 15378 R-ALL-74722 H+ [endosome lumen] R-DDI-917841 https://reactome.org/PathwayBrowser/#/R-DDI-917841 Acidification of Tf:TfR1 containing endosome IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-917979 https://reactome.org/PathwayBrowser/#/R-DDI-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-9619024 https://reactome.org/PathwayBrowser/#/R-DDI-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9695949 https://reactome.org/PathwayBrowser/#/R-DDI-9695949 SPHK2 phosphorylates sphingoid IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9705714 https://reactome.org/PathwayBrowser/#/R-DDI-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9709098 https://reactome.org/PathwayBrowser/#/R-DDI-9709098 DHFR dimer reduces FOLA to DHF IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9727347 https://reactome.org/PathwayBrowser/#/R-DDI-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9727349 https://reactome.org/PathwayBrowser/#/R-DDI-9727349 XDH dehydrogenates xanthine to form urate IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9748945 https://reactome.org/PathwayBrowser/#/R-DDI-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9748957 https://reactome.org/PathwayBrowser/#/R-DDI-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9748991 https://reactome.org/PathwayBrowser/#/R-DDI-9748991 XDH oxidises 6MP to 6TU IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-9749647 https://reactome.org/PathwayBrowser/#/R-DDI-9749647 CES2 hydrolyzes ASA- IEA Dictyostelium discoideum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DDI-9749792 https://reactome.org/PathwayBrowser/#/R-DDI-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9756134 https://reactome.org/PathwayBrowser/#/R-DDI-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9756156 https://reactome.org/PathwayBrowser/#/R-DDI-9756156 UGT1A3 lactonizes ATV to ATVL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9756183 https://reactome.org/PathwayBrowser/#/R-DDI-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9758661 https://reactome.org/PathwayBrowser/#/R-DDI-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9758682 https://reactome.org/PathwayBrowser/#/R-DDI-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9759549 https://reactome.org/PathwayBrowser/#/R-DDI-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Dictyostelium discoideum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DDI-977317 https://reactome.org/PathwayBrowser/#/R-DDI-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9773976 https://reactome.org/PathwayBrowser/#/R-DDI-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9843721 https://reactome.org/PathwayBrowser/#/R-DDI-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9853499 https://reactome.org/PathwayBrowser/#/R-DDI-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9856871 https://reactome.org/PathwayBrowser/#/R-DDI-9856871 MDH1 reduces OA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9858321 https://reactome.org/PathwayBrowser/#/R-DDI-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9858589 https://reactome.org/PathwayBrowser/#/R-DDI-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9858590 https://reactome.org/PathwayBrowser/#/R-DDI-9858590 DLST transfers glutaryl to CoA IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9859148 https://reactome.org/PathwayBrowser/#/R-DDI-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9859172 https://reactome.org/PathwayBrowser/#/R-DDI-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9861616 https://reactome.org/PathwayBrowser/#/R-DDI-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9861734 https://reactome.org/PathwayBrowser/#/R-DDI-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Dictyostelium discoideum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DDI-9864415 https://reactome.org/PathwayBrowser/#/R-DDI-9864415 AAC1 imports a proton IEA Dictyostelium discoideum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DDI-9864415 https://reactome.org/PathwayBrowser/#/R-DDI-9864415 AAC1 imports a proton IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9915971 https://reactome.org/PathwayBrowser/#/R-DDI-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9915997 https://reactome.org/PathwayBrowser/#/R-DDI-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DDI-9937295 https://reactome.org/PathwayBrowser/#/R-DDI-9937295 SRD5A3 reduces polyprenal to dolichal IEA Dictyostelium discoideum 15378 R-ALL-70106 H+ [cytosol] R-DME-111524 https://reactome.org/PathwayBrowser/#/R-DME-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1222516 https://reactome.org/PathwayBrowser/#/R-DME-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Drosophila melanogaster 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DME-1222516 https://reactome.org/PathwayBrowser/#/R-DME-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1237045 https://reactome.org/PathwayBrowser/#/R-DME-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1237047 https://reactome.org/PathwayBrowser/#/R-DME-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1237059 https://reactome.org/PathwayBrowser/#/R-DME-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1237081 https://reactome.org/PathwayBrowser/#/R-DME-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1475017 https://reactome.org/PathwayBrowser/#/R-DME-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1475022 https://reactome.org/PathwayBrowser/#/R-DME-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-1475025 https://reactome.org/PathwayBrowser/#/R-DME-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1475026 https://reactome.org/PathwayBrowser/#/R-DME-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-1475028 https://reactome.org/PathwayBrowser/#/R-DME-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-1475032 https://reactome.org/PathwayBrowser/#/R-DME-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1475435 https://reactome.org/PathwayBrowser/#/R-DME-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1475436 https://reactome.org/PathwayBrowser/#/R-DME-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1497869 https://reactome.org/PathwayBrowser/#/R-DME-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-159790 https://reactome.org/PathwayBrowser/#/R-DME-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-1605797 https://reactome.org/PathwayBrowser/#/R-DME-1605797 SMPD1 hydrolyzes SPHM IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1606273 https://reactome.org/PathwayBrowser/#/R-DME-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1606288 https://reactome.org/PathwayBrowser/#/R-DME-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1614567 https://reactome.org/PathwayBrowser/#/R-DME-1614567 Excess homocysteine yields homolanthionine and H2S IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1614591 https://reactome.org/PathwayBrowser/#/R-DME-1614591 Excess cysteine yields lanthionine and H2S IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1614614 https://reactome.org/PathwayBrowser/#/R-DME-1614614 Cysteine is degraded to pyruvate and H2S IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1614631 https://reactome.org/PathwayBrowser/#/R-DME-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-163217 https://reactome.org/PathwayBrowser/#/R-DME-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-1638104 https://reactome.org/PathwayBrowser/#/R-DME-1638104 UGCG transfers glucose to ceramide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-1638845 https://reactome.org/PathwayBrowser/#/R-DME-1638845 CERK phosphorylates CERA to form C1P IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-164651 https://reactome.org/PathwayBrowser/#/R-DME-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-164834 https://reactome.org/PathwayBrowser/#/R-DME-164834 Enzyme-bound ATP is released IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-164834 https://reactome.org/PathwayBrowser/#/R-DME-164834 Enzyme-bound ATP is released IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-169270 https://reactome.org/PathwayBrowser/#/R-DME-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-173597 https://reactome.org/PathwayBrowser/#/R-DME-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-174389 https://reactome.org/PathwayBrowser/#/R-DME-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-174392 https://reactome.org/PathwayBrowser/#/R-DME-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-189425 https://reactome.org/PathwayBrowser/#/R-DME-189425 UROD decarboxylates URO3 to COPRO3 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-189439 https://reactome.org/PathwayBrowser/#/R-DME-189439 ALAD condenses 2 dALAs to form PBG IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-189442 https://reactome.org/PathwayBrowser/#/R-DME-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-189465 https://reactome.org/PathwayBrowser/#/R-DME-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-190182 https://reactome.org/PathwayBrowser/#/R-DME-190182 UROD decarboxylates URO1 to COPRO1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-191323 https://reactome.org/PathwayBrowser/#/R-DME-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-191352 https://reactome.org/PathwayBrowser/#/R-DME-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-192033 https://reactome.org/PathwayBrowser/#/R-DME-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-192036 https://reactome.org/PathwayBrowser/#/R-DME-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-192067 https://reactome.org/PathwayBrowser/#/R-DME-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-192160 https://reactome.org/PathwayBrowser/#/R-DME-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193064 https://reactome.org/PathwayBrowser/#/R-DME-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-193455 https://reactome.org/PathwayBrowser/#/R-DME-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-193508 https://reactome.org/PathwayBrowser/#/R-DME-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193746 https://reactome.org/PathwayBrowser/#/R-DME-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193755 https://reactome.org/PathwayBrowser/#/R-DME-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193758 https://reactome.org/PathwayBrowser/#/R-DME-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193781 https://reactome.org/PathwayBrowser/#/R-DME-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193800 https://reactome.org/PathwayBrowser/#/R-DME-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193821 https://reactome.org/PathwayBrowser/#/R-DME-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193824 https://reactome.org/PathwayBrowser/#/R-DME-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-193841 https://reactome.org/PathwayBrowser/#/R-DME-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-194023 https://reactome.org/PathwayBrowser/#/R-DME-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-194698 https://reactome.org/PathwayBrowser/#/R-DME-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196060 https://reactome.org/PathwayBrowser/#/R-DME-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196753 https://reactome.org/PathwayBrowser/#/R-DME-196753 2xPPCS ligates PPanK with Cys IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196840 https://reactome.org/PathwayBrowser/#/R-DME-196840 3xPPCDC:3FMN decarboxylates PPC IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196857 https://reactome.org/PathwayBrowser/#/R-DME-196857 PANK2 phosphorylates PanK IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196929 https://reactome.org/PathwayBrowser/#/R-DME-196929 FLAD1 phosphorylates FMN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-196964 https://reactome.org/PathwayBrowser/#/R-DME-196964 RFK:Mg2+ phosphorylates RIB IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-197198 https://reactome.org/PathwayBrowser/#/R-DME-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-197235 https://reactome.org/PathwayBrowser/#/R-DME-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-197271 https://reactome.org/PathwayBrowser/#/R-DME-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-197963 https://reactome.org/PathwayBrowser/#/R-DME-197963 DHFR2 reduces FOLA to DHF IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-197972 https://reactome.org/PathwayBrowser/#/R-DME-197972 DHF is reduced to tetrahydrofolate (THF) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-198824 https://reactome.org/PathwayBrowser/#/R-DME-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-199203 https://reactome.org/PathwayBrowser/#/R-DME-199203 PANK1/3 phosphorylate PanK IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200423 https://reactome.org/PathwayBrowser/#/R-DME-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-200474 https://reactome.org/PathwayBrowser/#/R-DME-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15378 R-ALL-9668967 H+ [nucleoplasm] R-DME-200512 https://reactome.org/PathwayBrowser/#/R-DME-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200555 https://reactome.org/PathwayBrowser/#/R-DME-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200644 https://reactome.org/PathwayBrowser/#/R-DME-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200646 https://reactome.org/PathwayBrowser/#/R-DME-200646 Cytosolic folate export across the plasma membrane IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-200646 https://reactome.org/PathwayBrowser/#/R-DME-200646 Cytosolic folate export across the plasma membrane IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200676 https://reactome.org/PathwayBrowser/#/R-DME-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200718 https://reactome.org/PathwayBrowser/#/R-DME-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-200729 https://reactome.org/PathwayBrowser/#/R-DME-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-200729 https://reactome.org/PathwayBrowser/#/R-DME-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-202111 https://reactome.org/PathwayBrowser/#/R-DME-202111 AKT1 phosphorylates eNOS IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-203613 https://reactome.org/PathwayBrowser/#/R-DME-203613 Depalmitoylation of eNOS IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-203946 https://reactome.org/PathwayBrowser/#/R-DME-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-204617 https://reactome.org/PathwayBrowser/#/R-DME-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-204647 https://reactome.org/PathwayBrowser/#/R-DME-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-209973 https://reactome.org/PathwayBrowser/#/R-DME-209973 Tyrosine is diiodinated IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-210404 https://reactome.org/PathwayBrowser/#/R-DME-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161187 https://reactome.org/PathwayBrowser/#/R-DME-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161549 https://reactome.org/PathwayBrowser/#/R-DME-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161614 https://reactome.org/PathwayBrowser/#/R-DME-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161779 https://reactome.org/PathwayBrowser/#/R-DME-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2162078 https://reactome.org/PathwayBrowser/#/R-DME-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162186 https://reactome.org/PathwayBrowser/#/R-DME-2162186 COQ3 methylates DeMQ10H2 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162187 https://reactome.org/PathwayBrowser/#/R-DME-2162187 COQ6 hydroxylates DHB IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162188 https://reactome.org/PathwayBrowser/#/R-DME-2162188 COQ5 methylates MDMQ10H2 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162193 https://reactome.org/PathwayBrowser/#/R-DME-2162193 COQ3 methylates DHDB IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2162195 https://reactome.org/PathwayBrowser/#/R-DME-2162195 COQ4 decarboxylates MHDB IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2395512 https://reactome.org/PathwayBrowser/#/R-DME-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2395517 https://reactome.org/PathwayBrowser/#/R-DME-2395517 NADPH transfers electrons to FDXR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2395873 https://reactome.org/PathwayBrowser/#/R-DME-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2395879 https://reactome.org/PathwayBrowser/#/R-DME-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2395965 https://reactome.org/PathwayBrowser/#/R-DME-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2453833 https://reactome.org/PathwayBrowser/#/R-DME-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2464822 https://reactome.org/PathwayBrowser/#/R-DME-2464822 RDH12 reduces atRAL to atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2465940 https://reactome.org/PathwayBrowser/#/R-DME-2465940 atRAL is reduced to atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2509827 https://reactome.org/PathwayBrowser/#/R-DME-2509827 ITPA hydrolyses ITP to IMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2509831 https://reactome.org/PathwayBrowser/#/R-DME-2509831 ITPA hydrolyses XTP to XMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2509838 https://reactome.org/PathwayBrowser/#/R-DME-2509838 ITPA hydrolyses dITP to dIMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-DME-264615 https://reactome.org/PathwayBrowser/#/R-DME-264615 Loading of acetylcholine in synaptic vesicles IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-266070 https://reactome.org/PathwayBrowser/#/R-DME-266070 LTC4 is exported from the cytosol by ABCC1 IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-2671885 https://reactome.org/PathwayBrowser/#/R-DME-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2730692 https://reactome.org/PathwayBrowser/#/R-DME-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Drosophila melanogaster 15378 R-ALL-74722 H+ [endosome lumen] R-DME-2730692 https://reactome.org/PathwayBrowser/#/R-DME-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2730959 https://reactome.org/PathwayBrowser/#/R-DME-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-2730959 https://reactome.org/PathwayBrowser/#/R-DME-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2855252 https://reactome.org/PathwayBrowser/#/R-DME-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-2872444 https://reactome.org/PathwayBrowser/#/R-DME-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-2872444 https://reactome.org/PathwayBrowser/#/R-DME-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-2889070 https://reactome.org/PathwayBrowser/#/R-DME-2889070 SLC9B2 exchanges Na+ for H+ IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-2889070 https://reactome.org/PathwayBrowser/#/R-DME-2889070 SLC9B2 exchanges Na+ for H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322001 https://reactome.org/PathwayBrowser/#/R-DME-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322003 https://reactome.org/PathwayBrowser/#/R-DME-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322009 https://reactome.org/PathwayBrowser/#/R-DME-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322014 https://reactome.org/PathwayBrowser/#/R-DME-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322019 https://reactome.org/PathwayBrowser/#/R-DME-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322025 https://reactome.org/PathwayBrowser/#/R-DME-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3322041 https://reactome.org/PathwayBrowser/#/R-DME-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-3323050 https://reactome.org/PathwayBrowser/#/R-DME-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-350901 https://reactome.org/PathwayBrowser/#/R-DME-350901 Iodide is organified IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-352174 https://reactome.org/PathwayBrowser/#/R-DME-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-352182 https://reactome.org/PathwayBrowser/#/R-DME-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-372448 https://reactome.org/PathwayBrowser/#/R-DME-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-373867 https://reactome.org/PathwayBrowser/#/R-DME-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-373875 https://reactome.org/PathwayBrowser/#/R-DME-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-375405 https://reactome.org/PathwayBrowser/#/R-DME-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-375405 https://reactome.org/PathwayBrowser/#/R-DME-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-375417 https://reactome.org/PathwayBrowser/#/R-DME-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3780994 https://reactome.org/PathwayBrowser/#/R-DME-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-3781024 https://reactome.org/PathwayBrowser/#/R-DME-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-380608 https://reactome.org/PathwayBrowser/#/R-DME-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-389540 https://reactome.org/PathwayBrowser/#/R-DME-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-389550 https://reactome.org/PathwayBrowser/#/R-DME-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-389609 https://reactome.org/PathwayBrowser/#/R-DME-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-389826 https://reactome.org/PathwayBrowser/#/R-DME-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-389995 https://reactome.org/PathwayBrowser/#/R-DME-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-390251 https://reactome.org/PathwayBrowser/#/R-DME-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-390393 https://reactome.org/PathwayBrowser/#/R-DME-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-390425 https://reactome.org/PathwayBrowser/#/R-DME-390425 FAR1 reduces PalmCoA to HXOL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-390438 https://reactome.org/PathwayBrowser/#/R-DME-390438 FAR2 reduces PalmCoA to HXOL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-418365 https://reactome.org/PathwayBrowser/#/R-DME-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Drosophila melanogaster 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-DME-418365 https://reactome.org/PathwayBrowser/#/R-DME-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-425577 https://reactome.org/PathwayBrowser/#/R-DME-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-425965 https://reactome.org/PathwayBrowser/#/R-DME-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Drosophila melanogaster 15378 R-ALL-425999 H+ [late endosome lumen] R-DME-425965 https://reactome.org/PathwayBrowser/#/R-DME-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-425983 https://reactome.org/PathwayBrowser/#/R-DME-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Drosophila melanogaster 15378 R-ALL-425978 H+ [early endosome lumen] R-DME-425983 https://reactome.org/PathwayBrowser/#/R-DME-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-425994 https://reactome.org/PathwayBrowser/#/R-DME-425994 Na+/H+ exchanger transport (at cell membrane) IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-425994 https://reactome.org/PathwayBrowser/#/R-DME-425994 Na+/H+ exchanger transport (at cell membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-426015 https://reactome.org/PathwayBrowser/#/R-DME-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-426015 https://reactome.org/PathwayBrowser/#/R-DME-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-427555 https://reactome.org/PathwayBrowser/#/R-DME-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-427555 https://reactome.org/PathwayBrowser/#/R-DME-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-427910 https://reactome.org/PathwayBrowser/#/R-DME-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-427910 https://reactome.org/PathwayBrowser/#/R-DME-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-427998 https://reactome.org/PathwayBrowser/#/R-DME-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-428015 https://reactome.org/PathwayBrowser/#/R-DME-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428052 https://reactome.org/PathwayBrowser/#/R-DME-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Drosophila melanogaster 15378 R-ALL-428548 H+ [synaptic vesicle] R-DME-428052 https://reactome.org/PathwayBrowser/#/R-DME-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428123 https://reactome.org/PathwayBrowser/#/R-DME-428123 KDSR reduces 3-ketosphingoid IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428127 https://reactome.org/PathwayBrowser/#/R-DME-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428185 https://reactome.org/PathwayBrowser/#/R-DME-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428273 https://reactome.org/PathwayBrowser/#/R-DME-428273 SPHK1 phosphorylates sphingoid IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428585 https://reactome.org/PathwayBrowser/#/R-DME-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-428585 https://reactome.org/PathwayBrowser/#/R-DME-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-428625 https://reactome.org/PathwayBrowser/#/R-DME-428625 Vesicular inhibitory amino acid transport IEA Drosophila melanogaster 15378 R-ALL-428548 H+ [synaptic vesicle] R-DME-428625 https://reactome.org/PathwayBrowser/#/R-DME-428625 Vesicular inhibitory amino acid transport IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-429157 https://reactome.org/PathwayBrowser/#/R-DME-429157 ABCC4 accumulation of dense granule contents IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-429698 https://reactome.org/PathwayBrowser/#/R-DME-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-429714 https://reactome.org/PathwayBrowser/#/R-DME-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-433698 https://reactome.org/PathwayBrowser/#/R-DME-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DME-435171 https://reactome.org/PathwayBrowser/#/R-DME-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-435349 https://reactome.org/PathwayBrowser/#/R-DME-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-435349 https://reactome.org/PathwayBrowser/#/R-DME-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-444393 https://reactome.org/PathwayBrowser/#/R-DME-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-444393 https://reactome.org/PathwayBrowser/#/R-DME-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-444419 https://reactome.org/PathwayBrowser/#/R-DME-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-444419 https://reactome.org/PathwayBrowser/#/R-DME-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-446195 https://reactome.org/PathwayBrowser/#/R-DME-446195 DOLK phosphorylates DCHOL to DOLP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-446221 https://reactome.org/PathwayBrowser/#/R-DME-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-446277 https://reactome.org/PathwayBrowser/#/R-DME-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-446277 https://reactome.org/PathwayBrowser/#/R-DME-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-446278 https://reactome.org/PathwayBrowser/#/R-DME-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-446278 https://reactome.org/PathwayBrowser/#/R-DME-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-504054 https://reactome.org/PathwayBrowser/#/R-DME-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-508040 https://reactome.org/PathwayBrowser/#/R-DME-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-508308 https://reactome.org/PathwayBrowser/#/R-DME-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-508369 https://reactome.org/PathwayBrowser/#/R-DME-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-508473 https://reactome.org/PathwayBrowser/#/R-DME-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5340130 https://reactome.org/PathwayBrowser/#/R-DME-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-5340130 https://reactome.org/PathwayBrowser/#/R-DME-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5362518 https://reactome.org/PathwayBrowser/#/R-DME-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5362522 https://reactome.org/PathwayBrowser/#/R-DME-5362522 ALDHs oxidise atRAL to atRA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5362564 https://reactome.org/PathwayBrowser/#/R-DME-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5362721 https://reactome.org/PathwayBrowser/#/R-DME-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5419165 https://reactome.org/PathwayBrowser/#/R-DME-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-548800 https://reactome.org/PathwayBrowser/#/R-DME-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-548814 https://reactome.org/PathwayBrowser/#/R-DME-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-548815 https://reactome.org/PathwayBrowser/#/R-DME-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-548818 https://reactome.org/PathwayBrowser/#/R-DME-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-548831 https://reactome.org/PathwayBrowser/#/R-DME-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5615668 https://reactome.org/PathwayBrowser/#/R-DME-5615668 AKR1C3 reduces atRAL to atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5652172 https://reactome.org/PathwayBrowser/#/R-DME-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5652195 https://reactome.org/PathwayBrowser/#/R-DME-5652195 SORD oxidizes D-sorbitol to Fru IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5661240 https://reactome.org/PathwayBrowser/#/R-DME-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5661256 https://reactome.org/PathwayBrowser/#/R-DME-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5661290 https://reactome.org/PathwayBrowser/#/R-DME-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5662471 https://reactome.org/PathwayBrowser/#/R-DME-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-5690046 https://reactome.org/PathwayBrowser/#/R-DME-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Drosophila melanogaster 15378 R-ALL-428040 H+ [lysosomal lumen] R-DME-5690517 https://reactome.org/PathwayBrowser/#/R-DME-5690517 PPT1 hydrolyses palmitoylated proteins IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5692237 https://reactome.org/PathwayBrowser/#/R-DME-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5692261 https://reactome.org/PathwayBrowser/#/R-DME-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5692283 https://reactome.org/PathwayBrowser/#/R-DME-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-5693347 https://reactome.org/PathwayBrowser/#/R-DME-5693347 CRYM reduces P2C to PPCA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5693390 https://reactome.org/PathwayBrowser/#/R-DME-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-5693691 https://reactome.org/PathwayBrowser/#/R-DME-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-5693967 https://reactome.org/PathwayBrowser/#/R-DME-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-5694018 https://reactome.org/PathwayBrowser/#/R-DME-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5694462 https://reactome.org/PathwayBrowser/#/R-DME-5694462 ABHD6,12 hydrolyse 3AG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-5696080 https://reactome.org/PathwayBrowser/#/R-DME-5696080 ALDH3B1 oxidises HXAL to PALM IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-5696091 https://reactome.org/PathwayBrowser/#/R-DME-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-5696822 https://reactome.org/PathwayBrowser/#/R-DME-5696822 AKR1B15 reduces EST17b to E1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6783221 https://reactome.org/PathwayBrowser/#/R-DME-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6783939 https://reactome.org/PathwayBrowser/#/R-DME-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6784224 https://reactome.org/PathwayBrowser/#/R-DME-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6787642 https://reactome.org/PathwayBrowser/#/R-DME-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6787757 https://reactome.org/PathwayBrowser/#/R-DME-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6788611 https://reactome.org/PathwayBrowser/#/R-DME-6788611 HYKK phosphorylates 5HLYS IEA Drosophila melanogaster 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DME-6789031 https://reactome.org/PathwayBrowser/#/R-DME-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DME-6789126 https://reactome.org/PathwayBrowser/#/R-DME-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6793590 https://reactome.org/PathwayBrowser/#/R-DME-6793590 LIPT2 transfers octanoyl group to GCSH IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6793591 https://reactome.org/PathwayBrowser/#/R-DME-6793591 LIAS synthesizes lipoyl-GCSH IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6798317 https://reactome.org/PathwayBrowser/#/R-DME-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6798335 https://reactome.org/PathwayBrowser/#/R-DME-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6799495 https://reactome.org/PathwayBrowser/#/R-DME-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6801342 https://reactome.org/PathwayBrowser/#/R-DME-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6803771 https://reactome.org/PathwayBrowser/#/R-DME-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6806967 https://reactome.org/PathwayBrowser/#/R-DME-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6807826 https://reactome.org/PathwayBrowser/#/R-DME-6807826 LDHAL6B reduces PYR to LACT IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6808464 https://reactome.org/PathwayBrowser/#/R-DME-6808464 ALDH3B2 oxidises HXAL to PALM IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-6808487 https://reactome.org/PathwayBrowser/#/R-DME-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6808496 https://reactome.org/PathwayBrowser/#/R-DME-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Drosophila melanogaster 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DME-6810474 https://reactome.org/PathwayBrowser/#/R-DME-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6813749 https://reactome.org/PathwayBrowser/#/R-DME-6813749 ALDH1A1 oxidises GA to DGA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-6814165 https://reactome.org/PathwayBrowser/#/R-DME-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70286 https://reactome.org/PathwayBrowser/#/R-DME-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70333 https://reactome.org/PathwayBrowser/#/R-DME-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70377 https://reactome.org/PathwayBrowser/#/R-DME-70377 G6PD multimers dehydrogenate G6P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70420 https://reactome.org/PathwayBrowser/#/R-DME-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70449 https://reactome.org/PathwayBrowser/#/R-DME-70449 GADPH tetramer dehydrogenates GA3P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70467 https://reactome.org/PathwayBrowser/#/R-DME-70467 PFK tetramer phosphorylates Fru(6)P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70482 https://reactome.org/PathwayBrowser/#/R-DME-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70501 https://reactome.org/PathwayBrowser/#/R-DME-70501 PC carboxylates PYR to OA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70510 https://reactome.org/PathwayBrowser/#/R-DME-70510 LDH tetramer oxidises LACT to PYR IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70589 https://reactome.org/PathwayBrowser/#/R-DME-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70600 https://reactome.org/PathwayBrowser/#/R-DME-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-70606 https://reactome.org/PathwayBrowser/#/R-DME-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70664 https://reactome.org/PathwayBrowser/#/R-DME-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70670 https://reactome.org/PathwayBrowser/#/R-DME-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70745 https://reactome.org/PathwayBrowser/#/R-DME-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70773 https://reactome.org/PathwayBrowser/#/R-DME-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70800 https://reactome.org/PathwayBrowser/#/R-DME-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70837 https://reactome.org/PathwayBrowser/#/R-DME-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70881 https://reactome.org/PathwayBrowser/#/R-DME-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70885 https://reactome.org/PathwayBrowser/#/R-DME-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70893 https://reactome.org/PathwayBrowser/#/R-DME-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70938 https://reactome.org/PathwayBrowser/#/R-DME-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70940 https://reactome.org/PathwayBrowser/#/R-DME-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70941 https://reactome.org/PathwayBrowser/#/R-DME-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70975 https://reactome.org/PathwayBrowser/#/R-DME-70975 CS acetylates OA to citrate IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-70979 https://reactome.org/PathwayBrowser/#/R-DME-70979 MDH2 dimer dehydrogenates MAL IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-71046 https://reactome.org/PathwayBrowser/#/R-DME-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71130 https://reactome.org/PathwayBrowser/#/R-DME-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71181 https://reactome.org/PathwayBrowser/#/R-DME-71181 FAH cleaves 4FAA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71296 https://reactome.org/PathwayBrowser/#/R-DME-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-71401 https://reactome.org/PathwayBrowser/#/R-DME-71401 OGDH dimer decarboxylates 2-OG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71541 https://reactome.org/PathwayBrowser/#/R-DME-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71670 https://reactome.org/PathwayBrowser/#/R-DME-71670 PKM dephosphorylates PEP to PYR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71691 https://reactome.org/PathwayBrowser/#/R-DME-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71707 https://reactome.org/PathwayBrowser/#/R-DME-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-71723 https://reactome.org/PathwayBrowser/#/R-DME-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71802 https://reactome.org/PathwayBrowser/#/R-DME-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-71849 https://reactome.org/PathwayBrowser/#/R-DME-71849 LDH tetramer reduces PYR to LACT IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73564 https://reactome.org/PathwayBrowser/#/R-DME-73564 UMPS dimer decarboxylates OMP to UMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73571 https://reactome.org/PathwayBrowser/#/R-DME-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73573 https://reactome.org/PathwayBrowser/#/R-DME-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73577 https://reactome.org/PathwayBrowser/#/R-DME-73577 CAD hexamer transforms L-Gln to CAP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73585 https://reactome.org/PathwayBrowser/#/R-DME-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73589 https://reactome.org/PathwayBrowser/#/R-DME-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73591 https://reactome.org/PathwayBrowser/#/R-DME-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73616 https://reactome.org/PathwayBrowser/#/R-DME-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73618 https://reactome.org/PathwayBrowser/#/R-DME-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73620 https://reactome.org/PathwayBrowser/#/R-DME-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73647 https://reactome.org/PathwayBrowser/#/R-DME-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Drosophila melanogaster 15378 R-ALL-9668967 H+ [nucleoplasm] R-DME-73666 https://reactome.org/PathwayBrowser/#/R-DME-73666 dUTP + H2O => dUMP + pyrophosphate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73792 https://reactome.org/PathwayBrowser/#/R-DME-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73794 https://reactome.org/PathwayBrowser/#/R-DME-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73805 https://reactome.org/PathwayBrowser/#/R-DME-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73806 https://reactome.org/PathwayBrowser/#/R-DME-73806 AIR + CO2 => CAIR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73810 https://reactome.org/PathwayBrowser/#/R-DME-73810 FGAM + ATP => AIR + ADP + Pi IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73812 https://reactome.org/PathwayBrowser/#/R-DME-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73813 https://reactome.org/PathwayBrowser/#/R-DME-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-73814 https://reactome.org/PathwayBrowser/#/R-DME-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-73912 https://reactome.org/PathwayBrowser/#/R-DME-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-73920 https://reactome.org/PathwayBrowser/#/R-DME-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-74255 https://reactome.org/PathwayBrowser/#/R-DME-74255 Guanine + H2O => Xanthine + NH4+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-74723 https://reactome.org/PathwayBrowser/#/R-DME-74723 Endosome acidification IEA Drosophila melanogaster 15378 R-ALL-74722 H+ [endosome lumen] R-DME-74723 https://reactome.org/PathwayBrowser/#/R-DME-74723 Endosome acidification IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-74872 https://reactome.org/PathwayBrowser/#/R-DME-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-749452 https://reactome.org/PathwayBrowser/#/R-DME-749452 The Ligand:GPCR:Gq complex dissociates IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-75851 https://reactome.org/PathwayBrowser/#/R-DME-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-75872 https://reactome.org/PathwayBrowser/#/R-DME-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-75883 https://reactome.org/PathwayBrowser/#/R-DME-75883 DHRS7B reduces GO3P to HXDG3P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-75889 https://reactome.org/PathwayBrowser/#/R-DME-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-77283 https://reactome.org/PathwayBrowser/#/R-DME-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-77303 https://reactome.org/PathwayBrowser/#/R-DME-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-8851356 https://reactome.org/PathwayBrowser/#/R-DME-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-8851396 https://reactome.org/PathwayBrowser/#/R-DME-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8862137 https://reactome.org/PathwayBrowser/#/R-DME-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-8863494 https://reactome.org/PathwayBrowser/#/R-DME-8863494 ASICs bind STOML3, (STOM) IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-8863761 https://reactome.org/PathwayBrowser/#/R-DME-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Drosophila melanogaster 15378 R-ALL-9668967 H+ [nucleoplasm] R-DME-8866601 https://reactome.org/PathwayBrowser/#/R-DME-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8869606 https://reactome.org/PathwayBrowser/#/R-DME-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8869607 https://reactome.org/PathwayBrowser/#/R-DME-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8869627 https://reactome.org/PathwayBrowser/#/R-DME-8869627 NMRK2 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8869633 https://reactome.org/PathwayBrowser/#/R-DME-8869633 NMRK1 phosphorylates NR to yield NMN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8875623 https://reactome.org/PathwayBrowser/#/R-DME-8875623 SLC25A18,22 import L-Glu, H+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-8875623 https://reactome.org/PathwayBrowser/#/R-DME-8875623 SLC25A18,22 import L-Glu, H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8876789 https://reactome.org/PathwayBrowser/#/R-DME-8876789 CARNMT1 methylates CARN to Anserine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8876889 https://reactome.org/PathwayBrowser/#/R-DME-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-8878914 https://reactome.org/PathwayBrowser/#/R-DME-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-888548 https://reactome.org/PathwayBrowser/#/R-DME-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-888572 https://reactome.org/PathwayBrowser/#/R-DME-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-888577 https://reactome.org/PathwayBrowser/#/R-DME-888577 Synthesis of GABA by GAD2 IEA Drosophila melanogaster 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DME-8933635 https://reactome.org/PathwayBrowser/#/R-DME-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8936442 https://reactome.org/PathwayBrowser/#/R-DME-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8939959 https://reactome.org/PathwayBrowser/#/R-DME-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-8940070 https://reactome.org/PathwayBrowser/#/R-DME-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-8952873 https://reactome.org/PathwayBrowser/#/R-DME-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-8955030 https://reactome.org/PathwayBrowser/#/R-DME-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8955760 https://reactome.org/PathwayBrowser/#/R-DME-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8955844 https://reactome.org/PathwayBrowser/#/R-DME-8955844 RBKS phosphorylates ribose to R5P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-8959510 https://reactome.org/PathwayBrowser/#/R-DME-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9009950 https://reactome.org/PathwayBrowser/#/R-DME-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9011595 https://reactome.org/PathwayBrowser/#/R-DME-9011595 GSTZ1 dimer dehalogenates DCA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9012016 https://reactome.org/PathwayBrowser/#/R-DME-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9012036 https://reactome.org/PathwayBrowser/#/R-DME-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9024766 https://reactome.org/PathwayBrowser/#/R-DME-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 15378 R-ALL-74722 H+ [endosome lumen] R-DME-917841 https://reactome.org/PathwayBrowser/#/R-DME-917841 Acidification of Tf:TfR1 containing endosome IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-917979 https://reactome.org/PathwayBrowser/#/R-DME-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-9619024 https://reactome.org/PathwayBrowser/#/R-DME-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-9645220 https://reactome.org/PathwayBrowser/#/R-DME-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-9650165 https://reactome.org/PathwayBrowser/#/R-DME-9650165 ASIC trimers bind H+ IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9695949 https://reactome.org/PathwayBrowser/#/R-DME-9695949 SPHK2 phosphorylates sphingoid IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9705714 https://reactome.org/PathwayBrowser/#/R-DME-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9709098 https://reactome.org/PathwayBrowser/#/R-DME-9709098 DHFR dimer reduces FOLA to DHF IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9727347 https://reactome.org/PathwayBrowser/#/R-DME-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9727349 https://reactome.org/PathwayBrowser/#/R-DME-9727349 XDH dehydrogenates xanthine to form urate IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9731661 https://reactome.org/PathwayBrowser/#/R-DME-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9748945 https://reactome.org/PathwayBrowser/#/R-DME-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9748957 https://reactome.org/PathwayBrowser/#/R-DME-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9748991 https://reactome.org/PathwayBrowser/#/R-DME-9748991 XDH oxidises 6MP to 6TU IEA Drosophila melanogaster 15378 R-ALL-351626 H+ [extracellular region] R-DME-9749609 https://reactome.org/PathwayBrowser/#/R-DME-9749609 BCHE hydrolyzes ASA- IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-9749647 https://reactome.org/PathwayBrowser/#/R-DME-9749647 CES2 hydrolyzes ASA- IEA Drosophila melanogaster 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DME-9749792 https://reactome.org/PathwayBrowser/#/R-DME-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-975629 https://reactome.org/PathwayBrowser/#/R-DME-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9758661 https://reactome.org/PathwayBrowser/#/R-DME-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9758682 https://reactome.org/PathwayBrowser/#/R-DME-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9759259 https://reactome.org/PathwayBrowser/#/R-DME-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9760094 https://reactome.org/PathwayBrowser/#/R-DME-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-977301 https://reactome.org/PathwayBrowser/#/R-DME-977301 Histidine is decarboxylated to histamine IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-977348 https://reactome.org/PathwayBrowser/#/R-DME-977348 PHGDH tetramer dehydrogenates 3PG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9773976 https://reactome.org/PathwayBrowser/#/R-DME-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9794270 https://reactome.org/PathwayBrowser/#/R-DME-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Drosophila melanogaster 15378 R-ALL-9668967 H+ [nucleoplasm] R-DME-9825790 https://reactome.org/PathwayBrowser/#/R-DME-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9837337 https://reactome.org/PathwayBrowser/#/R-DME-9837337 DCAKD phosphorylates DP-CoA IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9843721 https://reactome.org/PathwayBrowser/#/R-DME-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-9845516 https://reactome.org/PathwayBrowser/#/R-DME-9845516 B3GALT4 transfers Gal to gangliosides IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-9846477 https://reactome.org/PathwayBrowser/#/R-DME-9846477 A4GALT transfers galactose to LacCer IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-9846501 https://reactome.org/PathwayBrowser/#/R-DME-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Drosophila melanogaster 15378 R-ALL-425969 H+ [Golgi lumen] R-DME-9851347 https://reactome.org/PathwayBrowser/#/R-DME-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9853499 https://reactome.org/PathwayBrowser/#/R-DME-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9856871 https://reactome.org/PathwayBrowser/#/R-DME-9856871 MDH1 reduces OA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9858321 https://reactome.org/PathwayBrowser/#/R-DME-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9858589 https://reactome.org/PathwayBrowser/#/R-DME-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9858590 https://reactome.org/PathwayBrowser/#/R-DME-9858590 DLST transfers glutaryl to CoA IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9859148 https://reactome.org/PathwayBrowser/#/R-DME-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9859172 https://reactome.org/PathwayBrowser/#/R-DME-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9861616 https://reactome.org/PathwayBrowser/#/R-DME-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9861660 https://reactome.org/PathwayBrowser/#/R-DME-9861660 ME1 tetramer decarboxylates OA to PYR IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9861734 https://reactome.org/PathwayBrowser/#/R-DME-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Drosophila melanogaster 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DME-9864415 https://reactome.org/PathwayBrowser/#/R-DME-9864415 AAC1 imports a proton IEA Drosophila melanogaster 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DME-9864415 https://reactome.org/PathwayBrowser/#/R-DME-9864415 AAC1 imports a proton IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9909159 https://reactome.org/PathwayBrowser/#/R-DME-9909159 HK1 phosphorylates Mannose to Man6P IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9915971 https://reactome.org/PathwayBrowser/#/R-DME-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9915997 https://reactome.org/PathwayBrowser/#/R-DME-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9937295 https://reactome.org/PathwayBrowser/#/R-DME-9937295 SRD5A3 reduces polyprenal to dolichal IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9937298 https://reactome.org/PathwayBrowser/#/R-DME-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DME-9937340 https://reactome.org/PathwayBrowser/#/R-DME-9937340 DHRSX reduces dolichal to dolichol IEA Drosophila melanogaster 15378 R-ALL-70106 H+ [cytosol] R-DRE-111215 https://reactome.org/PathwayBrowser/#/R-DRE-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-111524 https://reactome.org/PathwayBrowser/#/R-DRE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-111883 https://reactome.org/PathwayBrowser/#/R-DRE-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1222516 https://reactome.org/PathwayBrowser/#/R-DRE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Danio rerio 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DRE-1222516 https://reactome.org/PathwayBrowser/#/R-DRE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Danio rerio 15378 R-ALL-2000349 H+ [phagolysosome] R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-1237047 https://reactome.org/PathwayBrowser/#/R-DRE-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-1237059 https://reactome.org/PathwayBrowser/#/R-DRE-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-1475017 https://reactome.org/PathwayBrowser/#/R-DRE-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1475022 https://reactome.org/PathwayBrowser/#/R-DRE-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-1475025 https://reactome.org/PathwayBrowser/#/R-DRE-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1475026 https://reactome.org/PathwayBrowser/#/R-DRE-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-1475028 https://reactome.org/PathwayBrowser/#/R-DRE-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-1475032 https://reactome.org/PathwayBrowser/#/R-DRE-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1475435 https://reactome.org/PathwayBrowser/#/R-DRE-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1475436 https://reactome.org/PathwayBrowser/#/R-DRE-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1497869 https://reactome.org/PathwayBrowser/#/R-DRE-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-158609 https://reactome.org/PathwayBrowser/#/R-DRE-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1606273 https://reactome.org/PathwayBrowser/#/R-DRE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1606288 https://reactome.org/PathwayBrowser/#/R-DRE-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1614567 https://reactome.org/PathwayBrowser/#/R-DRE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1614591 https://reactome.org/PathwayBrowser/#/R-DRE-1614591 Excess cysteine yields lanthionine and H2S IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1614614 https://reactome.org/PathwayBrowser/#/R-DRE-1614614 Cysteine is degraded to pyruvate and H2S IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1614631 https://reactome.org/PathwayBrowser/#/R-DRE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-163217 https://reactome.org/PathwayBrowser/#/R-DRE-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-1638104 https://reactome.org/PathwayBrowser/#/R-DRE-1638104 UGCG transfers glucose to ceramide IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-164651 https://reactome.org/PathwayBrowser/#/R-DRE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-164834 https://reactome.org/PathwayBrowser/#/R-DRE-164834 Enzyme-bound ATP is released IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-164834 https://reactome.org/PathwayBrowser/#/R-DRE-164834 Enzyme-bound ATP is released IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-169270 https://reactome.org/PathwayBrowser/#/R-DRE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 UCP1 imports a proton IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-170026 https://reactome.org/PathwayBrowser/#/R-DRE-170026 UCP1 imports a proton IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-173597 https://reactome.org/PathwayBrowser/#/R-DRE-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-174389 https://reactome.org/PathwayBrowser/#/R-DRE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-174392 https://reactome.org/PathwayBrowser/#/R-DRE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-189425 https://reactome.org/PathwayBrowser/#/R-DRE-189425 UROD decarboxylates URO3 to COPRO3 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-189439 https://reactome.org/PathwayBrowser/#/R-DRE-189439 ALAD condenses 2 dALAs to form PBG IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-189442 https://reactome.org/PathwayBrowser/#/R-DRE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-189465 https://reactome.org/PathwayBrowser/#/R-DRE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-190182 https://reactome.org/PathwayBrowser/#/R-DRE-190182 UROD decarboxylates URO1 to COPRO1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-191352 https://reactome.org/PathwayBrowser/#/R-DRE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-192097 https://reactome.org/PathwayBrowser/#/R-DRE-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193064 https://reactome.org/PathwayBrowser/#/R-DRE-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193073 https://reactome.org/PathwayBrowser/#/R-DRE-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193789 https://reactome.org/PathwayBrowser/#/R-DRE-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193816 https://reactome.org/PathwayBrowser/#/R-DRE-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194023 https://reactome.org/PathwayBrowser/#/R-DRE-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194632 https://reactome.org/PathwayBrowser/#/R-DRE-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194642 https://reactome.org/PathwayBrowser/#/R-DRE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-ALL-194688 H+ [nuclear envelope] R-DRE-194674 https://reactome.org/PathwayBrowser/#/R-DRE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194689 https://reactome.org/PathwayBrowser/#/R-DRE-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194698 https://reactome.org/PathwayBrowser/#/R-DRE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-194718 https://reactome.org/PathwayBrowser/#/R-DRE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196060 https://reactome.org/PathwayBrowser/#/R-DRE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196350 https://reactome.org/PathwayBrowser/#/R-DRE-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196372 https://reactome.org/PathwayBrowser/#/R-DRE-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196402 https://reactome.org/PathwayBrowser/#/R-DRE-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196417 https://reactome.org/PathwayBrowser/#/R-DRE-196417 Reduction of desmosterol to cholesterol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196753 https://reactome.org/PathwayBrowser/#/R-DRE-196753 2xPPCS ligates PPanK with Cys IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196754 https://reactome.org/PathwayBrowser/#/R-DRE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196773 https://reactome.org/PathwayBrowser/#/R-DRE-196773 COASY phosphorylates DP-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196929 https://reactome.org/PathwayBrowser/#/R-DRE-196929 FLAD1 phosphorylates FMN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-196955 https://reactome.org/PathwayBrowser/#/R-DRE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-197198 https://reactome.org/PathwayBrowser/#/R-DRE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-197235 https://reactome.org/PathwayBrowser/#/R-DRE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-197271 https://reactome.org/PathwayBrowser/#/R-DRE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-197963 https://reactome.org/PathwayBrowser/#/R-DRE-197963 DHFR2 reduces FOLA to DHF IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-197972 https://reactome.org/PathwayBrowser/#/R-DRE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-198824 https://reactome.org/PathwayBrowser/#/R-DRE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-199203 https://reactome.org/PathwayBrowser/#/R-DRE-199203 PANK1/3 phosphorylate PanK IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-200512 https://reactome.org/PathwayBrowser/#/R-DRE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-200644 https://reactome.org/PathwayBrowser/#/R-DRE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-200646 https://reactome.org/PathwayBrowser/#/R-DRE-200646 Cytosolic folate export across the plasma membrane IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-200646 https://reactome.org/PathwayBrowser/#/R-DRE-200646 Cytosolic folate export across the plasma membrane IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-200676 https://reactome.org/PathwayBrowser/#/R-DRE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-200718 https://reactome.org/PathwayBrowser/#/R-DRE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-200729 https://reactome.org/PathwayBrowser/#/R-DRE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-200729 https://reactome.org/PathwayBrowser/#/R-DRE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-204617 https://reactome.org/PathwayBrowser/#/R-DRE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-204647 https://reactome.org/PathwayBrowser/#/R-DRE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-209821 https://reactome.org/PathwayBrowser/#/R-DRE-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-210404 https://reactome.org/PathwayBrowser/#/R-DRE-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161187 https://reactome.org/PathwayBrowser/#/R-DRE-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161651 https://reactome.org/PathwayBrowser/#/R-DRE-2161651 PGE2 is converted to PGF2a by CBR1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161779 https://reactome.org/PathwayBrowser/#/R-DRE-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2162078 https://reactome.org/PathwayBrowser/#/R-DRE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162186 https://reactome.org/PathwayBrowser/#/R-DRE-2162186 COQ3 methylates DeMQ10H2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162187 https://reactome.org/PathwayBrowser/#/R-DRE-2162187 COQ6 hydroxylates DHB IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162188 https://reactome.org/PathwayBrowser/#/R-DRE-2162188 COQ5 methylates MDMQ10H2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162193 https://reactome.org/PathwayBrowser/#/R-DRE-2162193 COQ3 methylates DHDB IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2162195 https://reactome.org/PathwayBrowser/#/R-DRE-2162195 COQ4 decarboxylates MHDB IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2395512 https://reactome.org/PathwayBrowser/#/R-DRE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-2395517 https://reactome.org/PathwayBrowser/#/R-DRE-2395517 NADPH transfers electrons to FDXR IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395818 https://reactome.org/PathwayBrowser/#/R-DRE-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395849 https://reactome.org/PathwayBrowser/#/R-DRE-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395872 https://reactome.org/PathwayBrowser/#/R-DRE-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395873 https://reactome.org/PathwayBrowser/#/R-DRE-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395879 https://reactome.org/PathwayBrowser/#/R-DRE-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2395965 https://reactome.org/PathwayBrowser/#/R-DRE-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2408524 https://reactome.org/PathwayBrowser/#/R-DRE-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2453833 https://reactome.org/PathwayBrowser/#/R-DRE-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2454081 https://reactome.org/PathwayBrowser/#/R-DRE-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2464822 https://reactome.org/PathwayBrowser/#/R-DRE-2464822 RDH12 reduces atRAL to atROL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2465940 https://reactome.org/PathwayBrowser/#/R-DRE-2465940 atRAL is reduced to atROL IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-2509793 https://reactome.org/PathwayBrowser/#/R-DRE-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-2509816 https://reactome.org/PathwayBrowser/#/R-DRE-2509816 NUDT16 hydrolyses IDP to IMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2509827 https://reactome.org/PathwayBrowser/#/R-DRE-2509827 ITPA hydrolyses ITP to IMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2509831 https://reactome.org/PathwayBrowser/#/R-DRE-2509831 ITPA hydrolyses XTP to XMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2509838 https://reactome.org/PathwayBrowser/#/R-DRE-2509838 ITPA hydrolyses dITP to dIMP IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-2534378 https://reactome.org/PathwayBrowser/#/R-DRE-2534378 Hv1 Mediated H+ Permeability IEA Danio rerio 15378 R-ALL-1132304 H+ [cytoplasm] R-DRE-2534378 https://reactome.org/PathwayBrowser/#/R-DRE-2534378 Hv1 Mediated H+ Permeability IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-DRE-264615 https://reactome.org/PathwayBrowser/#/R-DRE-264615 Loading of acetylcholine in synaptic vesicles IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-2671885 https://reactome.org/PathwayBrowser/#/R-DRE-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2730692 https://reactome.org/PathwayBrowser/#/R-DRE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Danio rerio 15378 R-ALL-74722 H+ [endosome lumen] R-DRE-2730692 https://reactome.org/PathwayBrowser/#/R-DRE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-2855252 https://reactome.org/PathwayBrowser/#/R-DRE-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3095889 https://reactome.org/PathwayBrowser/#/R-DRE-3095889 MMACHC dealkylates RCbl IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3149519 https://reactome.org/PathwayBrowser/#/R-DRE-3149519 MMACHC decyanates CNCbl IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3322001 https://reactome.org/PathwayBrowser/#/R-DRE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3322003 https://reactome.org/PathwayBrowser/#/R-DRE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3322025 https://reactome.org/PathwayBrowser/#/R-DRE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3322041 https://reactome.org/PathwayBrowser/#/R-DRE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-352182 https://reactome.org/PathwayBrowser/#/R-DRE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-372448 https://reactome.org/PathwayBrowser/#/R-DRE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-3781024 https://reactome.org/PathwayBrowser/#/R-DRE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-380608 https://reactome.org/PathwayBrowser/#/R-DRE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-389540 https://reactome.org/PathwayBrowser/#/R-DRE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-389550 https://reactome.org/PathwayBrowser/#/R-DRE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-389609 https://reactome.org/PathwayBrowser/#/R-DRE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-389826 https://reactome.org/PathwayBrowser/#/R-DRE-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-390304 https://reactome.org/PathwayBrowser/#/R-DRE-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-390438 https://reactome.org/PathwayBrowser/#/R-DRE-390438 FAR2 reduces PalmCoA to HXOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-418365 https://reactome.org/PathwayBrowser/#/R-DRE-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Danio rerio 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-DRE-418365 https://reactome.org/PathwayBrowser/#/R-DRE-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-425983 https://reactome.org/PathwayBrowser/#/R-DRE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Danio rerio 15378 R-ALL-425978 H+ [early endosome lumen] R-DRE-425983 https://reactome.org/PathwayBrowser/#/R-DRE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-425994 https://reactome.org/PathwayBrowser/#/R-DRE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-425994 https://reactome.org/PathwayBrowser/#/R-DRE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-426015 https://reactome.org/PathwayBrowser/#/R-DRE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-426015 https://reactome.org/PathwayBrowser/#/R-DRE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-426043 https://reactome.org/PathwayBrowser/#/R-DRE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-427555 https://reactome.org/PathwayBrowser/#/R-DRE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-427555 https://reactome.org/PathwayBrowser/#/R-DRE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-427910 https://reactome.org/PathwayBrowser/#/R-DRE-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-427910 https://reactome.org/PathwayBrowser/#/R-DRE-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-427998 https://reactome.org/PathwayBrowser/#/R-DRE-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-428015 https://reactome.org/PathwayBrowser/#/R-DRE-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428052 https://reactome.org/PathwayBrowser/#/R-DRE-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Danio rerio 15378 R-ALL-428548 H+ [synaptic vesicle] R-DRE-428052 https://reactome.org/PathwayBrowser/#/R-DRE-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428127 https://reactome.org/PathwayBrowser/#/R-DRE-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428185 https://reactome.org/PathwayBrowser/#/R-DRE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428585 https://reactome.org/PathwayBrowser/#/R-DRE-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-ALL-428040 H+ [lysosomal lumen] R-DRE-428585 https://reactome.org/PathwayBrowser/#/R-DRE-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-428625 https://reactome.org/PathwayBrowser/#/R-DRE-428625 Vesicular inhibitory amino acid transport IEA Danio rerio 15378 R-ALL-428548 H+ [synaptic vesicle] R-DRE-428625 https://reactome.org/PathwayBrowser/#/R-DRE-428625 Vesicular inhibitory amino acid transport IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-429016 https://reactome.org/PathwayBrowser/#/R-DRE-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-429157 https://reactome.org/PathwayBrowser/#/R-DRE-429157 ABCC4 accumulation of dense granule contents IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-429698 https://reactome.org/PathwayBrowser/#/R-DRE-429698 PRKD1,2,3 phosphorylates CERT1-2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-429714 https://reactome.org/PathwayBrowser/#/R-DRE-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-433698 https://reactome.org/PathwayBrowser/#/R-DRE-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-434650 https://reactome.org/PathwayBrowser/#/R-DRE-434650 MATEs mediate extrusion of xenobiotics IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DRE-435171 https://reactome.org/PathwayBrowser/#/R-DRE-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-435349 https://reactome.org/PathwayBrowser/#/R-DRE-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-435349 https://reactome.org/PathwayBrowser/#/R-DRE-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-444393 https://reactome.org/PathwayBrowser/#/R-DRE-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-444393 https://reactome.org/PathwayBrowser/#/R-DRE-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-444419 https://reactome.org/PathwayBrowser/#/R-DRE-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-444419 https://reactome.org/PathwayBrowser/#/R-DRE-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-446195 https://reactome.org/PathwayBrowser/#/R-DRE-446195 DOLK phosphorylates DCHOL to DOLP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-446200 https://reactome.org/PathwayBrowser/#/R-DRE-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-446221 https://reactome.org/PathwayBrowser/#/R-DRE-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-446277 https://reactome.org/PathwayBrowser/#/R-DRE-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-446277 https://reactome.org/PathwayBrowser/#/R-DRE-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-446278 https://reactome.org/PathwayBrowser/#/R-DRE-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-446278 https://reactome.org/PathwayBrowser/#/R-DRE-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-450971 https://reactome.org/PathwayBrowser/#/R-DRE-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-469659 https://reactome.org/PathwayBrowser/#/R-DRE-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-504054 https://reactome.org/PathwayBrowser/#/R-DRE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-508369 https://reactome.org/PathwayBrowser/#/R-DRE-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-508473 https://reactome.org/PathwayBrowser/#/R-DRE-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-514604 https://reactome.org/PathwayBrowser/#/R-DRE-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5340130 https://reactome.org/PathwayBrowser/#/R-DRE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-ALL-428040 H+ [lysosomal lumen] R-DRE-5340130 https://reactome.org/PathwayBrowser/#/R-DRE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5362518 https://reactome.org/PathwayBrowser/#/R-DRE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5362522 https://reactome.org/PathwayBrowser/#/R-DRE-5362522 ALDHs oxidise atRAL to atRA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5362564 https://reactome.org/PathwayBrowser/#/R-DRE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5362721 https://reactome.org/PathwayBrowser/#/R-DRE-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5419165 https://reactome.org/PathwayBrowser/#/R-DRE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5423637 https://reactome.org/PathwayBrowser/#/R-DRE-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-548800 https://reactome.org/PathwayBrowser/#/R-DRE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-548814 https://reactome.org/PathwayBrowser/#/R-DRE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-548815 https://reactome.org/PathwayBrowser/#/R-DRE-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-548818 https://reactome.org/PathwayBrowser/#/R-DRE-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5652172 https://reactome.org/PathwayBrowser/#/R-DRE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5661240 https://reactome.org/PathwayBrowser/#/R-DRE-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5661256 https://reactome.org/PathwayBrowser/#/R-DRE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5661290 https://reactome.org/PathwayBrowser/#/R-DRE-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-5690042 https://reactome.org/PathwayBrowser/#/R-DRE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Danio rerio 15378 R-ALL-428040 H+ [lysosomal lumen] R-DRE-5690046 https://reactome.org/PathwayBrowser/#/R-DRE-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Danio rerio 15378 R-ALL-428040 H+ [lysosomal lumen] R-DRE-5690517 https://reactome.org/PathwayBrowser/#/R-DRE-5690517 PPT1 hydrolyses palmitoylated proteins IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5692237 https://reactome.org/PathwayBrowser/#/R-DRE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5692261 https://reactome.org/PathwayBrowser/#/R-DRE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5692283 https://reactome.org/PathwayBrowser/#/R-DRE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-5693347 https://reactome.org/PathwayBrowser/#/R-DRE-5693347 CRYM reduces P2C to PPCA IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-5693691 https://reactome.org/PathwayBrowser/#/R-DRE-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-5693967 https://reactome.org/PathwayBrowser/#/R-DRE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-5694018 https://reactome.org/PathwayBrowser/#/R-DRE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5694462 https://reactome.org/PathwayBrowser/#/R-DRE-5694462 ABHD6,12 hydrolyse 3AG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5696021 https://reactome.org/PathwayBrowser/#/R-DRE-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5696080 https://reactome.org/PathwayBrowser/#/R-DRE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-5696091 https://reactome.org/PathwayBrowser/#/R-DRE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5696101 https://reactome.org/PathwayBrowser/#/R-DRE-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5696457 https://reactome.org/PathwayBrowser/#/R-DRE-5696457 BDH2 dehydrogenates 3HBA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-5696822 https://reactome.org/PathwayBrowser/#/R-DRE-5696822 AKR1B15 reduces EST17b to E1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-5696838 https://reactome.org/PathwayBrowser/#/R-DRE-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-597628 https://reactome.org/PathwayBrowser/#/R-DRE-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6783221 https://reactome.org/PathwayBrowser/#/R-DRE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6783939 https://reactome.org/PathwayBrowser/#/R-DRE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6783955 https://reactome.org/PathwayBrowser/#/R-DRE-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6784402 https://reactome.org/PathwayBrowser/#/R-DRE-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-6785933 https://reactome.org/PathwayBrowser/#/R-DRE-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-6786720 https://reactome.org/PathwayBrowser/#/R-DRE-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6787642 https://reactome.org/PathwayBrowser/#/R-DRE-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6788611 https://reactome.org/PathwayBrowser/#/R-DRE-6788611 HYKK phosphorylates 5HLYS IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6788999 https://reactome.org/PathwayBrowser/#/R-DRE-6788999 HV1-mediated H+ transfer IEA Danio rerio 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-DRE-6788999 https://reactome.org/PathwayBrowser/#/R-DRE-6788999 HV1-mediated H+ transfer IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6793590 https://reactome.org/PathwayBrowser/#/R-DRE-6793590 LIPT2 transfers octanoyl group to GCSH IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6793591 https://reactome.org/PathwayBrowser/#/R-DRE-6793591 LIAS synthesizes lipoyl-GCSH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6798317 https://reactome.org/PathwayBrowser/#/R-DRE-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6798335 https://reactome.org/PathwayBrowser/#/R-DRE-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6799495 https://reactome.org/PathwayBrowser/#/R-DRE-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6801342 https://reactome.org/PathwayBrowser/#/R-DRE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-6806647 https://reactome.org/PathwayBrowser/#/R-DRE-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6806831 https://reactome.org/PathwayBrowser/#/R-DRE-6806831 CYB5Rs reduce MetHb to HbA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6806967 https://reactome.org/PathwayBrowser/#/R-DRE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6807055 https://reactome.org/PathwayBrowser/#/R-DRE-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6807064 https://reactome.org/PathwayBrowser/#/R-DRE-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-6807826 https://reactome.org/PathwayBrowser/#/R-DRE-6807826 LDHAL6B reduces PYR to LACT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6808464 https://reactome.org/PathwayBrowser/#/R-DRE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6808496 https://reactome.org/PathwayBrowser/#/R-DRE-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-6809264 https://reactome.org/PathwayBrowser/#/R-DRE-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-6809287 https://reactome.org/PathwayBrowser/#/R-DRE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-6809810 https://reactome.org/PathwayBrowser/#/R-DRE-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-6810474 https://reactome.org/PathwayBrowser/#/R-DRE-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6810594 https://reactome.org/PathwayBrowser/#/R-DRE-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70355 https://reactome.org/PathwayBrowser/#/R-DRE-70355 GALK1 phosphorylates Gal to Gal1P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70420 https://reactome.org/PathwayBrowser/#/R-DRE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70449 https://reactome.org/PathwayBrowser/#/R-DRE-70449 GADPH tetramer dehydrogenates GA3P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70467 https://reactome.org/PathwayBrowser/#/R-DRE-70467 PFK tetramer phosphorylates Fru(6)P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70482 https://reactome.org/PathwayBrowser/#/R-DRE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70501 https://reactome.org/PathwayBrowser/#/R-DRE-70501 PC carboxylates PYR to OA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70510 https://reactome.org/PathwayBrowser/#/R-DRE-70510 LDH tetramer oxidises LACT to PYR IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70589 https://reactome.org/PathwayBrowser/#/R-DRE-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70600 https://reactome.org/PathwayBrowser/#/R-DRE-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-70606 https://reactome.org/PathwayBrowser/#/R-DRE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70664 https://reactome.org/PathwayBrowser/#/R-DRE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70679 https://reactome.org/PathwayBrowser/#/R-DRE-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70745 https://reactome.org/PathwayBrowser/#/R-DRE-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70837 https://reactome.org/PathwayBrowser/#/R-DRE-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70859 https://reactome.org/PathwayBrowser/#/R-DRE-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70881 https://reactome.org/PathwayBrowser/#/R-DRE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70885 https://reactome.org/PathwayBrowser/#/R-DRE-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70893 https://reactome.org/PathwayBrowser/#/R-DRE-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70938 https://reactome.org/PathwayBrowser/#/R-DRE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70940 https://reactome.org/PathwayBrowser/#/R-DRE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70941 https://reactome.org/PathwayBrowser/#/R-DRE-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70975 https://reactome.org/PathwayBrowser/#/R-DRE-70975 CS acetylates OA to citrate IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-70979 https://reactome.org/PathwayBrowser/#/R-DRE-70979 MDH2 dimer dehydrogenates MAL IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-71046 https://reactome.org/PathwayBrowser/#/R-DRE-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71130 https://reactome.org/PathwayBrowser/#/R-DRE-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71260 https://reactome.org/PathwayBrowser/#/R-DRE-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71286 https://reactome.org/PathwayBrowser/#/R-DRE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-71401 https://reactome.org/PathwayBrowser/#/R-DRE-71401 OGDH dimer decarboxylates 2-OG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71670 https://reactome.org/PathwayBrowser/#/R-DRE-71670 PKM dephosphorylates PEP to PYR IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71707 https://reactome.org/PathwayBrowser/#/R-DRE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-71723 https://reactome.org/PathwayBrowser/#/R-DRE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71802 https://reactome.org/PathwayBrowser/#/R-DRE-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-71849 https://reactome.org/PathwayBrowser/#/R-DRE-71849 LDH tetramer reduces PYR to LACT IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73580 https://reactome.org/PathwayBrowser/#/R-DRE-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73585 https://reactome.org/PathwayBrowser/#/R-DRE-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73589 https://reactome.org/PathwayBrowser/#/R-DRE-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73591 https://reactome.org/PathwayBrowser/#/R-DRE-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73596 https://reactome.org/PathwayBrowser/#/R-DRE-73596 dCMP + H2O => dUMP + NH4+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73616 https://reactome.org/PathwayBrowser/#/R-DRE-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73618 https://reactome.org/PathwayBrowser/#/R-DRE-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73620 https://reactome.org/PathwayBrowser/#/R-DRE-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73647 https://reactome.org/PathwayBrowser/#/R-DRE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-73666 https://reactome.org/PathwayBrowser/#/R-DRE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73794 https://reactome.org/PathwayBrowser/#/R-DRE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73805 https://reactome.org/PathwayBrowser/#/R-DRE-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73806 https://reactome.org/PathwayBrowser/#/R-DRE-73806 AIR + CO2 => CAIR IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73810 https://reactome.org/PathwayBrowser/#/R-DRE-73810 FGAM + ATP => AIR + ADP + Pi IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73813 https://reactome.org/PathwayBrowser/#/R-DRE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-73814 https://reactome.org/PathwayBrowser/#/R-DRE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-73912 https://reactome.org/PathwayBrowser/#/R-DRE-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-73920 https://reactome.org/PathwayBrowser/#/R-DRE-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-74255 https://reactome.org/PathwayBrowser/#/R-DRE-74255 Guanine + H2O => Xanthine + NH4+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-74723 https://reactome.org/PathwayBrowser/#/R-DRE-74723 Endosome acidification IEA Danio rerio 15378 R-ALL-74722 H+ [endosome lumen] R-DRE-74723 https://reactome.org/PathwayBrowser/#/R-DRE-74723 Endosome acidification IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-74872 https://reactome.org/PathwayBrowser/#/R-DRE-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-75872 https://reactome.org/PathwayBrowser/#/R-DRE-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-75883 https://reactome.org/PathwayBrowser/#/R-DRE-75883 DHRS7B reduces GO3P to HXDG3P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-75889 https://reactome.org/PathwayBrowser/#/R-DRE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77254 https://reactome.org/PathwayBrowser/#/R-DRE-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77283 https://reactome.org/PathwayBrowser/#/R-DRE-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77303 https://reactome.org/PathwayBrowser/#/R-DRE-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77312 https://reactome.org/PathwayBrowser/#/R-DRE-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77323 https://reactome.org/PathwayBrowser/#/R-DRE-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77331 https://reactome.org/PathwayBrowser/#/R-DRE-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-77342 https://reactome.org/PathwayBrowser/#/R-DRE-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8851089 https://reactome.org/PathwayBrowser/#/R-DRE-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8851396 https://reactome.org/PathwayBrowser/#/R-DRE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8851538 https://reactome.org/PathwayBrowser/#/R-DRE-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8851550 https://reactome.org/PathwayBrowser/#/R-DRE-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-8856223 https://reactome.org/PathwayBrowser/#/R-DRE-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-8862152 https://reactome.org/PathwayBrowser/#/R-DRE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8863494 https://reactome.org/PathwayBrowser/#/R-DRE-8863494 ASICs bind STOML3, (STOM) IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-8863761 https://reactome.org/PathwayBrowser/#/R-DRE-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-8866601 https://reactome.org/PathwayBrowser/#/R-DRE-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8869607 https://reactome.org/PathwayBrowser/#/R-DRE-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8869627 https://reactome.org/PathwayBrowser/#/R-DRE-8869627 NMRK2 phosphorylates NR to yield NMN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8875623 https://reactome.org/PathwayBrowser/#/R-DRE-8875623 SLC25A18,22 import L-Glu, H+ IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-8875623 https://reactome.org/PathwayBrowser/#/R-DRE-8875623 SLC25A18,22 import L-Glu, H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-888572 https://reactome.org/PathwayBrowser/#/R-DRE-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8936442 https://reactome.org/PathwayBrowser/#/R-DRE-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8939959 https://reactome.org/PathwayBrowser/#/R-DRE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8940070 https://reactome.org/PathwayBrowser/#/R-DRE-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8942575 https://reactome.org/PathwayBrowser/#/R-DRE-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-8952873 https://reactome.org/PathwayBrowser/#/R-DRE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-8954468 https://reactome.org/PathwayBrowser/#/R-DRE-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8955760 https://reactome.org/PathwayBrowser/#/R-DRE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8955844 https://reactome.org/PathwayBrowser/#/R-DRE-8955844 RBKS phosphorylates ribose to R5P IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-8959510 https://reactome.org/PathwayBrowser/#/R-DRE-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9011595 https://reactome.org/PathwayBrowser/#/R-DRE-9011595 GSTZ1 dimer dehalogenates DCA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9012016 https://reactome.org/PathwayBrowser/#/R-DRE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9012036 https://reactome.org/PathwayBrowser/#/R-DRE-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-9013198 https://reactome.org/PathwayBrowser/#/R-DRE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9024766 https://reactome.org/PathwayBrowser/#/R-DRE-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 15378 R-ALL-74722 H+ [endosome lumen] R-DRE-917841 https://reactome.org/PathwayBrowser/#/R-DRE-917841 Acidification of Tf:TfR1 containing endosome IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-9619024 https://reactome.org/PathwayBrowser/#/R-DRE-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Danio rerio 15378 R-ALL-351626 H+ [extracellular region] R-DRE-9650165 https://reactome.org/PathwayBrowser/#/R-DRE-9650165 ASIC trimers bind H+ IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9705713 https://reactome.org/PathwayBrowser/#/R-DRE-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9705714 https://reactome.org/PathwayBrowser/#/R-DRE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9709098 https://reactome.org/PathwayBrowser/#/R-DRE-9709098 DHFR dimer reduces FOLA to DHF IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9731228 https://reactome.org/PathwayBrowser/#/R-DRE-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9731590 https://reactome.org/PathwayBrowser/#/R-DRE-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9731613 https://reactome.org/PathwayBrowser/#/R-DRE-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9731632 https://reactome.org/PathwayBrowser/#/R-DRE-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9731661 https://reactome.org/PathwayBrowser/#/R-DRE-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9748945 https://reactome.org/PathwayBrowser/#/R-DRE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9748979 https://reactome.org/PathwayBrowser/#/R-DRE-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9748983 https://reactome.org/PathwayBrowser/#/R-DRE-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-9749647 https://reactome.org/PathwayBrowser/#/R-DRE-9749647 CES2 hydrolyzes ASA- IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-9749792 https://reactome.org/PathwayBrowser/#/R-DRE-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9755937 https://reactome.org/PathwayBrowser/#/R-DRE-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9756177 https://reactome.org/PathwayBrowser/#/R-DRE-9756177 PON1,3 hydrolyse ATVL to ATV IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-975629 https://reactome.org/PathwayBrowser/#/R-DRE-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9757706 https://reactome.org/PathwayBrowser/#/R-DRE-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9758661 https://reactome.org/PathwayBrowser/#/R-DRE-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9759259 https://reactome.org/PathwayBrowser/#/R-DRE-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9759549 https://reactome.org/PathwayBrowser/#/R-DRE-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Danio rerio 15378 R-ALL-193465 H+ [peroxisomal matrix] R-DRE-977317 https://reactome.org/PathwayBrowser/#/R-DRE-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9773976 https://reactome.org/PathwayBrowser/#/R-DRE-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9794270 https://reactome.org/PathwayBrowser/#/R-DRE-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Danio rerio 15378 R-ALL-9668967 H+ [nucleoplasm] R-DRE-9825790 https://reactome.org/PathwayBrowser/#/R-DRE-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9837337 https://reactome.org/PathwayBrowser/#/R-DRE-9837337 DCAKD phosphorylates DP-CoA IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-9844587 https://reactome.org/PathwayBrowser/#/R-DRE-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-9844860 https://reactome.org/PathwayBrowser/#/R-DRE-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-9846501 https://reactome.org/PathwayBrowser/#/R-DRE-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Danio rerio 15378 R-ALL-425969 H+ [Golgi lumen] R-DRE-9851347 https://reactome.org/PathwayBrowser/#/R-DRE-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9853499 https://reactome.org/PathwayBrowser/#/R-DRE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9854315 https://reactome.org/PathwayBrowser/#/R-DRE-9854315 CSKMT methylates Citrate Synthase IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9854415 https://reactome.org/PathwayBrowser/#/R-DRE-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9856871 https://reactome.org/PathwayBrowser/#/R-DRE-9856871 MDH1 reduces OA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9858321 https://reactome.org/PathwayBrowser/#/R-DRE-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9858589 https://reactome.org/PathwayBrowser/#/R-DRE-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9858590 https://reactome.org/PathwayBrowser/#/R-DRE-9858590 DLST transfers glutaryl to CoA IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9859148 https://reactome.org/PathwayBrowser/#/R-DRE-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9859172 https://reactome.org/PathwayBrowser/#/R-DRE-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9861660 https://reactome.org/PathwayBrowser/#/R-DRE-9861660 ME1 tetramer decarboxylates OA to PYR IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9864415 https://reactome.org/PathwayBrowser/#/R-DRE-9864415 AAC1 imports a proton IEA Danio rerio 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-DRE-9864415 https://reactome.org/PathwayBrowser/#/R-DRE-9864415 AAC1 imports a proton IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9909159 https://reactome.org/PathwayBrowser/#/R-DRE-9909159 HK1 phosphorylates Mannose to Man6P IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9915971 https://reactome.org/PathwayBrowser/#/R-DRE-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-DRE-9915993 https://reactome.org/PathwayBrowser/#/R-DRE-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9915997 https://reactome.org/PathwayBrowser/#/R-DRE-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Danio rerio 15378 R-ALL-113529 H+ [mitochondrial matrix] R-DRE-9929439 https://reactome.org/PathwayBrowser/#/R-DRE-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9937295 https://reactome.org/PathwayBrowser/#/R-DRE-9937295 SRD5A3 reduces polyprenal to dolichal IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9937298 https://reactome.org/PathwayBrowser/#/R-DRE-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-DRE-9937340 https://reactome.org/PathwayBrowser/#/R-DRE-9937340 DHRSX reduces dolichal to dolichol IEA Danio rerio 15378 R-ALL-70106 H+ [cytosol] R-ECO-1222667 https://reactome.org/PathwayBrowser/#/R-ECO-1222667 Iron is reduced and separates from enterobactin TAS Escherichia coli 15378 R-ALL-70106 H+ [cytosol] R-FCA-164926 https://reactome.org/PathwayBrowser/#/R-FCA-164926 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ TAS Felis catus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-109343 https://reactome.org/PathwayBrowser/#/R-GGA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-111215 https://reactome.org/PathwayBrowser/#/R-GGA-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-111524 https://reactome.org/PathwayBrowser/#/R-GGA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-111883 https://reactome.org/PathwayBrowser/#/R-GGA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-1222516 https://reactome.org/PathwayBrowser/#/R-GGA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Gallus gallus 15378 R-ALL-2000349 H+ [phagolysosome] R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1237045 https://reactome.org/PathwayBrowser/#/R-GGA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1237047 https://reactome.org/PathwayBrowser/#/R-GGA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1237059 https://reactome.org/PathwayBrowser/#/R-GGA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1237081 https://reactome.org/PathwayBrowser/#/R-GGA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1475017 https://reactome.org/PathwayBrowser/#/R-GGA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1475022 https://reactome.org/PathwayBrowser/#/R-GGA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-1475025 https://reactome.org/PathwayBrowser/#/R-GGA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1475026 https://reactome.org/PathwayBrowser/#/R-GGA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-1475028 https://reactome.org/PathwayBrowser/#/R-GGA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-1475032 https://reactome.org/PathwayBrowser/#/R-GGA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1475435 https://reactome.org/PathwayBrowser/#/R-GGA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1475436 https://reactome.org/PathwayBrowser/#/R-GGA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1497869 https://reactome.org/PathwayBrowser/#/R-GGA-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-158609 https://reactome.org/PathwayBrowser/#/R-GGA-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-1605797 https://reactome.org/PathwayBrowser/#/R-GGA-1605797 SMPD1 hydrolyzes SPHM IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1606273 https://reactome.org/PathwayBrowser/#/R-GGA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1606288 https://reactome.org/PathwayBrowser/#/R-GGA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-1606807 https://reactome.org/PathwayBrowser/#/R-GGA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-1614362 https://reactome.org/PathwayBrowser/#/R-GGA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1614567 https://reactome.org/PathwayBrowser/#/R-GGA-1614567 Excess homocysteine yields homolanthionine and H2S IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1614591 https://reactome.org/PathwayBrowser/#/R-GGA-1614591 Excess cysteine yields lanthionine and H2S IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1614614 https://reactome.org/PathwayBrowser/#/R-GGA-1614614 Cysteine is degraded to pyruvate and H2S IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1614631 https://reactome.org/PathwayBrowser/#/R-GGA-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-162730 https://reactome.org/PathwayBrowser/#/R-GGA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-163217 https://reactome.org/PathwayBrowser/#/R-GGA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-1638104 https://reactome.org/PathwayBrowser/#/R-GGA-1638104 UGCG transfers glucose to ceramide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1638845 https://reactome.org/PathwayBrowser/#/R-GGA-1638845 CERK phosphorylates CERA to form C1P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-1640164 https://reactome.org/PathwayBrowser/#/R-GGA-1640164 ENPP7 hydrolyzes sphingomyelin IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-164651 https://reactome.org/PathwayBrowser/#/R-GGA-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-164834 https://reactome.org/PathwayBrowser/#/R-GGA-164834 Enzyme-bound ATP is released IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-173597 https://reactome.org/PathwayBrowser/#/R-GGA-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-174389 https://reactome.org/PathwayBrowser/#/R-GGA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-174392 https://reactome.org/PathwayBrowser/#/R-GGA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-189425 https://reactome.org/PathwayBrowser/#/R-GGA-189425 UROD decarboxylates URO3 to COPRO3 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-189439 https://reactome.org/PathwayBrowser/#/R-GGA-189439 ALAD condenses 2 dALAs to form PBG IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-189442 https://reactome.org/PathwayBrowser/#/R-GGA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-189465 https://reactome.org/PathwayBrowser/#/R-GGA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-190182 https://reactome.org/PathwayBrowser/#/R-GGA-190182 UROD decarboxylates URO1 to COPRO1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191323 https://reactome.org/PathwayBrowser/#/R-GGA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191352 https://reactome.org/PathwayBrowser/#/R-GGA-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191402 https://reactome.org/PathwayBrowser/#/R-GGA-191402 Reduction of presqualene diphosphate to form squalene IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192033 https://reactome.org/PathwayBrowser/#/R-GGA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192067 https://reactome.org/PathwayBrowser/#/R-GGA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193064 https://reactome.org/PathwayBrowser/#/R-GGA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193073 https://reactome.org/PathwayBrowser/#/R-GGA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-193455 https://reactome.org/PathwayBrowser/#/R-GGA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-193508 https://reactome.org/PathwayBrowser/#/R-GGA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193746 https://reactome.org/PathwayBrowser/#/R-GGA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193755 https://reactome.org/PathwayBrowser/#/R-GGA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193821 https://reactome.org/PathwayBrowser/#/R-GGA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193824 https://reactome.org/PathwayBrowser/#/R-GGA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194023 https://reactome.org/PathwayBrowser/#/R-GGA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194632 https://reactome.org/PathwayBrowser/#/R-GGA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194642 https://reactome.org/PathwayBrowser/#/R-GGA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-ALL-194688 H+ [nuclear envelope] R-GGA-194674 https://reactome.org/PathwayBrowser/#/R-GGA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194689 https://reactome.org/PathwayBrowser/#/R-GGA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-194718 https://reactome.org/PathwayBrowser/#/R-GGA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196060 https://reactome.org/PathwayBrowser/#/R-GGA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196350 https://reactome.org/PathwayBrowser/#/R-GGA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196372 https://reactome.org/PathwayBrowser/#/R-GGA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196402 https://reactome.org/PathwayBrowser/#/R-GGA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196417 https://reactome.org/PathwayBrowser/#/R-GGA-196417 Reduction of desmosterol to cholesterol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196753 https://reactome.org/PathwayBrowser/#/R-GGA-196753 2xPPCS ligates PPanK with Cys IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196754 https://reactome.org/PathwayBrowser/#/R-GGA-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196773 https://reactome.org/PathwayBrowser/#/R-GGA-196773 COASY phosphorylates DP-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196840 https://reactome.org/PathwayBrowser/#/R-GGA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196857 https://reactome.org/PathwayBrowser/#/R-GGA-196857 PANK2 phosphorylates PanK IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196929 https://reactome.org/PathwayBrowser/#/R-GGA-196929 FLAD1 phosphorylates FMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-196964 https://reactome.org/PathwayBrowser/#/R-GGA-196964 RFK:Mg2+ phosphorylates RIB IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197198 https://reactome.org/PathwayBrowser/#/R-GGA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197235 https://reactome.org/PathwayBrowser/#/R-GGA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197250 https://reactome.org/PathwayBrowser/#/R-GGA-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197268 https://reactome.org/PathwayBrowser/#/R-GGA-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197271 https://reactome.org/PathwayBrowser/#/R-GGA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197963 https://reactome.org/PathwayBrowser/#/R-GGA-197963 DHFR2 reduces FOLA to DHF IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-197972 https://reactome.org/PathwayBrowser/#/R-GGA-197972 DHF is reduced to tetrahydrofolate (THF) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-198824 https://reactome.org/PathwayBrowser/#/R-GGA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-199203 https://reactome.org/PathwayBrowser/#/R-GGA-199203 PANK1/3 phosphorylate PanK IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-200474 https://reactome.org/PathwayBrowser/#/R-GGA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15378 R-ALL-9668967 H+ [nucleoplasm] R-GGA-200512 https://reactome.org/PathwayBrowser/#/R-GGA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200555 https://reactome.org/PathwayBrowser/#/R-GGA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200644 https://reactome.org/PathwayBrowser/#/R-GGA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200646 https://reactome.org/PathwayBrowser/#/R-GGA-200646 Cytosolic folate export across the plasma membrane IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-200646 https://reactome.org/PathwayBrowser/#/R-GGA-200646 Cytosolic folate export across the plasma membrane IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200676 https://reactome.org/PathwayBrowser/#/R-GGA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200718 https://reactome.org/PathwayBrowser/#/R-GGA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-200729 https://reactome.org/PathwayBrowser/#/R-GGA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-200729 https://reactome.org/PathwayBrowser/#/R-GGA-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-202111 https://reactome.org/PathwayBrowser/#/R-GGA-202111 AKT1 phosphorylates eNOS IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-203613 https://reactome.org/PathwayBrowser/#/R-GGA-203613 Depalmitoylation of eNOS IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-203946 https://reactome.org/PathwayBrowser/#/R-GGA-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-209772 https://reactome.org/PathwayBrowser/#/R-GGA-209772 Thyroxine is deiodinated to triiodothyronine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-209821 https://reactome.org/PathwayBrowser/#/R-GGA-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-209903 https://reactome.org/PathwayBrowser/#/R-GGA-209903 Noradrenaline is converted to adrenaline IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-209973 https://reactome.org/PathwayBrowser/#/R-GGA-209973 Tyrosine is diiodinated IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-210404 https://reactome.org/PathwayBrowser/#/R-GGA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161187 https://reactome.org/PathwayBrowser/#/R-GGA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161651 https://reactome.org/PathwayBrowser/#/R-GGA-2161651 PGE2 is converted to PGF2a by CBR1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161779 https://reactome.org/PathwayBrowser/#/R-GGA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2162078 https://reactome.org/PathwayBrowser/#/R-GGA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162186 https://reactome.org/PathwayBrowser/#/R-GGA-2162186 COQ3 methylates DeMQ10H2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162187 https://reactome.org/PathwayBrowser/#/R-GGA-2162187 COQ6 hydroxylates DHB IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162188 https://reactome.org/PathwayBrowser/#/R-GGA-2162188 COQ5 methylates MDMQ10H2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162193 https://reactome.org/PathwayBrowser/#/R-GGA-2162193 COQ3 methylates DHDB IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2162195 https://reactome.org/PathwayBrowser/#/R-GGA-2162195 COQ4 decarboxylates MHDB IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2395512 https://reactome.org/PathwayBrowser/#/R-GGA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2395517 https://reactome.org/PathwayBrowser/#/R-GGA-2395517 NADPH transfers electrons to FDXR IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2395818 https://reactome.org/PathwayBrowser/#/R-GGA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2395849 https://reactome.org/PathwayBrowser/#/R-GGA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2395869 https://reactome.org/PathwayBrowser/#/R-GGA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2395872 https://reactome.org/PathwayBrowser/#/R-GGA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2395876 https://reactome.org/PathwayBrowser/#/R-GGA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2408524 https://reactome.org/PathwayBrowser/#/R-GGA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2453833 https://reactome.org/PathwayBrowser/#/R-GGA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2454081 https://reactome.org/PathwayBrowser/#/R-GGA-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2464822 https://reactome.org/PathwayBrowser/#/R-GGA-2464822 RDH12 reduces atRAL to atROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2465940 https://reactome.org/PathwayBrowser/#/R-GGA-2465940 atRAL is reduced to atROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2465974 https://reactome.org/PathwayBrowser/#/R-GGA-2465974 An REH hydrolyses 11cRE to 11cROL TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2509827 https://reactome.org/PathwayBrowser/#/R-GGA-2509827 ITPA hydrolyses ITP to IMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2509831 https://reactome.org/PathwayBrowser/#/R-GGA-2509831 ITPA hydrolyses XTP to XMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2509838 https://reactome.org/PathwayBrowser/#/R-GGA-2509838 ITPA hydrolyses dITP to dIMP IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-2534378 https://reactome.org/PathwayBrowser/#/R-GGA-2534378 Hv1 Mediated H+ Permeability IEA Gallus gallus 15378 R-ALL-1132304 H+ [cytoplasm] R-GGA-2534378 https://reactome.org/PathwayBrowser/#/R-GGA-2534378 Hv1 Mediated H+ Permeability IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-GGA-264615 https://reactome.org/PathwayBrowser/#/R-GGA-264615 Loading of acetylcholine in synaptic vesicles IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-266070 https://reactome.org/PathwayBrowser/#/R-GGA-266070 LTC4 is exported from the cytosol by ABCC1 IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-2671885 https://reactome.org/PathwayBrowser/#/R-GGA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2730692 https://reactome.org/PathwayBrowser/#/R-GGA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Gallus gallus 15378 R-ALL-74722 H+ [endosome lumen] R-GGA-2730692 https://reactome.org/PathwayBrowser/#/R-GGA-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2730959 https://reactome.org/PathwayBrowser/#/R-GGA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-2730959 https://reactome.org/PathwayBrowser/#/R-GGA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2855252 https://reactome.org/PathwayBrowser/#/R-GGA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-2872444 https://reactome.org/PathwayBrowser/#/R-GGA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-2872444 https://reactome.org/PathwayBrowser/#/R-GGA-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-2889070 https://reactome.org/PathwayBrowser/#/R-GGA-2889070 SLC9B2 exchanges Na+ for H+ IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-2889070 https://reactome.org/PathwayBrowser/#/R-GGA-2889070 SLC9B2 exchanges Na+ for H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3095889 https://reactome.org/PathwayBrowser/#/R-GGA-3095889 MMACHC dealkylates RCbl IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3149518 https://reactome.org/PathwayBrowser/#/R-GGA-3149518 MTRR reduces cob(II)alamin to meCbl IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3149519 https://reactome.org/PathwayBrowser/#/R-GGA-3149519 MMACHC decyanates CNCbl IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-3159253 https://reactome.org/PathwayBrowser/#/R-GGA-3159253 MMAB adenosylates cob(I)alamin IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322001 https://reactome.org/PathwayBrowser/#/R-GGA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322003 https://reactome.org/PathwayBrowser/#/R-GGA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322009 https://reactome.org/PathwayBrowser/#/R-GGA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322014 https://reactome.org/PathwayBrowser/#/R-GGA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322019 https://reactome.org/PathwayBrowser/#/R-GGA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322025 https://reactome.org/PathwayBrowser/#/R-GGA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3322041 https://reactome.org/PathwayBrowser/#/R-GGA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-3323050 https://reactome.org/PathwayBrowser/#/R-GGA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-3323079 https://reactome.org/PathwayBrowser/#/R-GGA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-350901 https://reactome.org/PathwayBrowser/#/R-GGA-350901 Iodide is organified IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-352174 https://reactome.org/PathwayBrowser/#/R-GGA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-352921 https://reactome.org/PathwayBrowser/#/R-GGA-352921 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-352956 https://reactome.org/PathwayBrowser/#/R-GGA-352956 glyceraldehyde 3-phosphate + NAD+ + phosphate <=> 1,3-bisphosphoglycerate + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-372359 https://reactome.org/PathwayBrowser/#/R-GGA-372359 pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-372422 https://reactome.org/PathwayBrowser/#/R-GGA-372422 oxaloacetate + NADH + H+ <=> malate + NAD+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-372448 https://reactome.org/PathwayBrowser/#/R-GGA-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-372855 https://reactome.org/PathwayBrowser/#/R-GGA-372855 malate + NAD+ <=> oxaloacetate + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-372903 https://reactome.org/PathwayBrowser/#/R-GGA-372903 lactate + NAD+ <=> pyruvate + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-372910 https://reactome.org/PathwayBrowser/#/R-GGA-372910 pyruvate + NADH + H+ <=> lactate + NAD+ TAS Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-373024 https://reactome.org/PathwayBrowser/#/R-GGA-373024 isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-373042 https://reactome.org/PathwayBrowser/#/R-GGA-373042 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-373047 https://reactome.org/PathwayBrowser/#/R-GGA-373047 malate + NAD+ <=> oxaloacetate + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-373177 https://reactome.org/PathwayBrowser/#/R-GGA-373177 pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-373867 https://reactome.org/PathwayBrowser/#/R-GGA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-373875 https://reactome.org/PathwayBrowser/#/R-GGA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-373887 https://reactome.org/PathwayBrowser/#/R-GGA-373887 lactate + H+ [extracellular] <=> lactate + H+ [cytosol] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-373889 https://reactome.org/PathwayBrowser/#/R-GGA-373889 lactate + H+ [cytosol] <=> lactate + H+ [extracellular] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-375405 https://reactome.org/PathwayBrowser/#/R-GGA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-375417 https://reactome.org/PathwayBrowser/#/R-GGA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3780994 https://reactome.org/PathwayBrowser/#/R-GGA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-3781024 https://reactome.org/PathwayBrowser/#/R-GGA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-379048 https://reactome.org/PathwayBrowser/#/R-GGA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-380608 https://reactome.org/PathwayBrowser/#/R-GGA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-389540 https://reactome.org/PathwayBrowser/#/R-GGA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-389550 https://reactome.org/PathwayBrowser/#/R-GGA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-389609 https://reactome.org/PathwayBrowser/#/R-GGA-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-389826 https://reactome.org/PathwayBrowser/#/R-GGA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-389995 https://reactome.org/PathwayBrowser/#/R-GGA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-390251 https://reactome.org/PathwayBrowser/#/R-GGA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-390304 https://reactome.org/PathwayBrowser/#/R-GGA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-390425 https://reactome.org/PathwayBrowser/#/R-GGA-390425 FAR1 reduces PalmCoA to HXOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-390438 https://reactome.org/PathwayBrowser/#/R-GGA-390438 FAR2 reduces PalmCoA to HXOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-418365 https://reactome.org/PathwayBrowser/#/R-GGA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Gallus gallus 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-GGA-418365 https://reactome.org/PathwayBrowser/#/R-GGA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-419465 https://reactome.org/PathwayBrowser/#/R-GGA-419465 N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-421158 https://reactome.org/PathwayBrowser/#/R-GGA-421158 xanthine + H2O + NAD+ => urate + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-421161 https://reactome.org/PathwayBrowser/#/R-GGA-421161 hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-421222 https://reactome.org/PathwayBrowser/#/R-GGA-421222 inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-421447 https://reactome.org/PathwayBrowser/#/R-GGA-421447 protoporphyrin IX + Fe++ => heme + 2 H+ TAS Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-425577 https://reactome.org/PathwayBrowser/#/R-GGA-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-425965 https://reactome.org/PathwayBrowser/#/R-GGA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Gallus gallus 15378 R-ALL-425999 H+ [late endosome lumen] R-GGA-425965 https://reactome.org/PathwayBrowser/#/R-GGA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-425983 https://reactome.org/PathwayBrowser/#/R-GGA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Gallus gallus 15378 R-ALL-425978 H+ [early endosome lumen] R-GGA-425983 https://reactome.org/PathwayBrowser/#/R-GGA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-425994 https://reactome.org/PathwayBrowser/#/R-GGA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-425994 https://reactome.org/PathwayBrowser/#/R-GGA-425994 Na+/H+ exchanger transport (at cell membrane) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-426015 https://reactome.org/PathwayBrowser/#/R-GGA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-426015 https://reactome.org/PathwayBrowser/#/R-GGA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-426043 https://reactome.org/PathwayBrowser/#/R-GGA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-427555 https://reactome.org/PathwayBrowser/#/R-GGA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-427555 https://reactome.org/PathwayBrowser/#/R-GGA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-427910 https://reactome.org/PathwayBrowser/#/R-GGA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-427998 https://reactome.org/PathwayBrowser/#/R-GGA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-428007 https://reactome.org/PathwayBrowser/#/R-GGA-428007 Proton-coupled histidine and di-peptide cotransport IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-428015 https://reactome.org/PathwayBrowser/#/R-GGA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus 15378 R-ALL-428548 H+ [synaptic vesicle] R-GGA-428052 https://reactome.org/PathwayBrowser/#/R-GGA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428127 https://reactome.org/PathwayBrowser/#/R-GGA-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428185 https://reactome.org/PathwayBrowser/#/R-GGA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428273 https://reactome.org/PathwayBrowser/#/R-GGA-428273 SPHK1 phosphorylates sphingoid IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428585 https://reactome.org/PathwayBrowser/#/R-GGA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-428585 https://reactome.org/PathwayBrowser/#/R-GGA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus 15378 R-ALL-428548 H+ [synaptic vesicle] R-GGA-428625 https://reactome.org/PathwayBrowser/#/R-GGA-428625 Vesicular inhibitory amino acid transport IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-429016 https://reactome.org/PathwayBrowser/#/R-GGA-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-429101 https://reactome.org/PathwayBrowser/#/R-GGA-429101 HMIT co-transports myo-inositol with a proton IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-429157 https://reactome.org/PathwayBrowser/#/R-GGA-429157 ABCC4 accumulation of dense granule contents IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-433576 https://reactome.org/PathwayBrowser/#/R-GGA-433576 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-433698 https://reactome.org/PathwayBrowser/#/R-GGA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-434650 https://reactome.org/PathwayBrowser/#/R-GGA-434650 MATEs mediate extrusion of xenobiotics IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-435171 https://reactome.org/PathwayBrowser/#/R-GGA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-435349 https://reactome.org/PathwayBrowser/#/R-GGA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-435349 https://reactome.org/PathwayBrowser/#/R-GGA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-444393 https://reactome.org/PathwayBrowser/#/R-GGA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-444393 https://reactome.org/PathwayBrowser/#/R-GGA-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-444419 https://reactome.org/PathwayBrowser/#/R-GGA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-444419 https://reactome.org/PathwayBrowser/#/R-GGA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-444731 https://reactome.org/PathwayBrowser/#/R-GGA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-446195 https://reactome.org/PathwayBrowser/#/R-GGA-446195 DOLK phosphorylates DCHOL to DOLP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-446200 https://reactome.org/PathwayBrowser/#/R-GGA-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-446221 https://reactome.org/PathwayBrowser/#/R-GGA-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-446277 https://reactome.org/PathwayBrowser/#/R-GGA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-446277 https://reactome.org/PathwayBrowser/#/R-GGA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-446278 https://reactome.org/PathwayBrowser/#/R-GGA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-446278 https://reactome.org/PathwayBrowser/#/R-GGA-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-450971 https://reactome.org/PathwayBrowser/#/R-GGA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-469659 https://reactome.org/PathwayBrowser/#/R-GGA-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-504054 https://reactome.org/PathwayBrowser/#/R-GGA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-508040 https://reactome.org/PathwayBrowser/#/R-GGA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-508308 https://reactome.org/PathwayBrowser/#/R-GGA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-508369 https://reactome.org/PathwayBrowser/#/R-GGA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-508473 https://reactome.org/PathwayBrowser/#/R-GGA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-514604 https://reactome.org/PathwayBrowser/#/R-GGA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5263614 https://reactome.org/PathwayBrowser/#/R-GGA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5263616 https://reactome.org/PathwayBrowser/#/R-GGA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5340130 https://reactome.org/PathwayBrowser/#/R-GGA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-5340130 https://reactome.org/PathwayBrowser/#/R-GGA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5362518 https://reactome.org/PathwayBrowser/#/R-GGA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5362522 https://reactome.org/PathwayBrowser/#/R-GGA-5362522 ALDHs oxidise atRAL to atRA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5362564 https://reactome.org/PathwayBrowser/#/R-GGA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5362721 https://reactome.org/PathwayBrowser/#/R-GGA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5419165 https://reactome.org/PathwayBrowser/#/R-GGA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5423637 https://reactome.org/PathwayBrowser/#/R-GGA-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-548800 https://reactome.org/PathwayBrowser/#/R-GGA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-548814 https://reactome.org/PathwayBrowser/#/R-GGA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-548815 https://reactome.org/PathwayBrowser/#/R-GGA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-548818 https://reactome.org/PathwayBrowser/#/R-GGA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-548831 https://reactome.org/PathwayBrowser/#/R-GGA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5652172 https://reactome.org/PathwayBrowser/#/R-GGA-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5652195 https://reactome.org/PathwayBrowser/#/R-GGA-5652195 SORD oxidizes D-sorbitol to Fru IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5661240 https://reactome.org/PathwayBrowser/#/R-GGA-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5661256 https://reactome.org/PathwayBrowser/#/R-GGA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5661290 https://reactome.org/PathwayBrowser/#/R-GGA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5662471 https://reactome.org/PathwayBrowser/#/R-GGA-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Gallus gallus 15378 R-ALL-5668577 H+ [melanosome lumen] R-GGA-5662662 https://reactome.org/PathwayBrowser/#/R-GGA-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-5690042 https://reactome.org/PathwayBrowser/#/R-GGA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Gallus gallus 15378 R-ALL-428040 H+ [lysosomal lumen] R-GGA-5690517 https://reactome.org/PathwayBrowser/#/R-GGA-5690517 PPT1 hydrolyses palmitoylated proteins IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5692237 https://reactome.org/PathwayBrowser/#/R-GGA-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5692261 https://reactome.org/PathwayBrowser/#/R-GGA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5692283 https://reactome.org/PathwayBrowser/#/R-GGA-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-5693347 https://reactome.org/PathwayBrowser/#/R-GGA-5693347 CRYM reduces P2C to PPCA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5693390 https://reactome.org/PathwayBrowser/#/R-GGA-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-5693691 https://reactome.org/PathwayBrowser/#/R-GGA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-5693967 https://reactome.org/PathwayBrowser/#/R-GGA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-5694018 https://reactome.org/PathwayBrowser/#/R-GGA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5694462 https://reactome.org/PathwayBrowser/#/R-GGA-5694462 ABHD6,12 hydrolyse 3AG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5696021 https://reactome.org/PathwayBrowser/#/R-GGA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5696080 https://reactome.org/PathwayBrowser/#/R-GGA-5696080 ALDH3B1 oxidises HXAL to PALM IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5696101 https://reactome.org/PathwayBrowser/#/R-GGA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5696457 https://reactome.org/PathwayBrowser/#/R-GGA-5696457 BDH2 dehydrogenates 3HBA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-5696822 https://reactome.org/PathwayBrowser/#/R-GGA-5696822 AKR1B15 reduces EST17b to E1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-5696838 https://reactome.org/PathwayBrowser/#/R-GGA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-597628 https://reactome.org/PathwayBrowser/#/R-GGA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6783221 https://reactome.org/PathwayBrowser/#/R-GGA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6783939 https://reactome.org/PathwayBrowser/#/R-GGA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6783955 https://reactome.org/PathwayBrowser/#/R-GGA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6784402 https://reactome.org/PathwayBrowser/#/R-GGA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-6785933 https://reactome.org/PathwayBrowser/#/R-GGA-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6786245 https://reactome.org/PathwayBrowser/#/R-GGA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6786720 https://reactome.org/PathwayBrowser/#/R-GGA-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6787642 https://reactome.org/PathwayBrowser/#/R-GGA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6787757 https://reactome.org/PathwayBrowser/#/R-GGA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6788611 https://reactome.org/PathwayBrowser/#/R-GGA-6788611 HYKK phosphorylates 5HLYS IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6788999 https://reactome.org/PathwayBrowser/#/R-GGA-6788999 HV1-mediated H+ transfer IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-6788999 https://reactome.org/PathwayBrowser/#/R-GGA-6788999 HV1-mediated H+ transfer IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-6789031 https://reactome.org/PathwayBrowser/#/R-GGA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-6789126 https://reactome.org/PathwayBrowser/#/R-GGA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6793590 https://reactome.org/PathwayBrowser/#/R-GGA-6793590 LIPT2 transfers octanoyl group to GCSH IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6793591 https://reactome.org/PathwayBrowser/#/R-GGA-6793591 LIAS synthesizes lipoyl-GCSH IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6798335 https://reactome.org/PathwayBrowser/#/R-GGA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6799495 https://reactome.org/PathwayBrowser/#/R-GGA-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6799722 https://reactome.org/PathwayBrowser/#/R-GGA-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6801342 https://reactome.org/PathwayBrowser/#/R-GGA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6803771 https://reactome.org/PathwayBrowser/#/R-GGA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-6806647 https://reactome.org/PathwayBrowser/#/R-GGA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6806831 https://reactome.org/PathwayBrowser/#/R-GGA-6806831 CYB5Rs reduce MetHb to HbA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6806967 https://reactome.org/PathwayBrowser/#/R-GGA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6807055 https://reactome.org/PathwayBrowser/#/R-GGA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6807064 https://reactome.org/PathwayBrowser/#/R-GGA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6807826 https://reactome.org/PathwayBrowser/#/R-GGA-6807826 LDHAL6B reduces PYR to LACT IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6808464 https://reactome.org/PathwayBrowser/#/R-GGA-6808464 ALDH3B2 oxidises HXAL to PALM IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-6808487 https://reactome.org/PathwayBrowser/#/R-GGA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6809264 https://reactome.org/PathwayBrowser/#/R-GGA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6809287 https://reactome.org/PathwayBrowser/#/R-GGA-6809287 NUDT12 hydrolyses NADH to NMNH IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6809810 https://reactome.org/PathwayBrowser/#/R-GGA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-6810474 https://reactome.org/PathwayBrowser/#/R-GGA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6813749 https://reactome.org/PathwayBrowser/#/R-GGA-6813749 ALDH1A1 oxidises GA to DGA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-6814165 https://reactome.org/PathwayBrowser/#/R-GGA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70286 https://reactome.org/PathwayBrowser/#/R-GGA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70333 https://reactome.org/PathwayBrowser/#/R-GGA-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70355 https://reactome.org/PathwayBrowser/#/R-GGA-70355 GALK1 phosphorylates Gal to Gal1P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70420 https://reactome.org/PathwayBrowser/#/R-GGA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70449 https://reactome.org/PathwayBrowser/#/R-GGA-70449 GADPH tetramer dehydrogenates GA3P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70467 https://reactome.org/PathwayBrowser/#/R-GGA-70467 PFK tetramer phosphorylates Fru(6)P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70482 https://reactome.org/PathwayBrowser/#/R-GGA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70510 https://reactome.org/PathwayBrowser/#/R-GGA-70510 LDH tetramer oxidises LACT to PYR IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70589 https://reactome.org/PathwayBrowser/#/R-GGA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70599 https://reactome.org/PathwayBrowser/#/R-GGA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70600 https://reactome.org/PathwayBrowser/#/R-GGA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-70606 https://reactome.org/PathwayBrowser/#/R-GGA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70664 https://reactome.org/PathwayBrowser/#/R-GGA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70670 https://reactome.org/PathwayBrowser/#/R-GGA-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70679 https://reactome.org/PathwayBrowser/#/R-GGA-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70745 https://reactome.org/PathwayBrowser/#/R-GGA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70773 https://reactome.org/PathwayBrowser/#/R-GGA-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70800 https://reactome.org/PathwayBrowser/#/R-GGA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70837 https://reactome.org/PathwayBrowser/#/R-GGA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70859 https://reactome.org/PathwayBrowser/#/R-GGA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70881 https://reactome.org/PathwayBrowser/#/R-GGA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70885 https://reactome.org/PathwayBrowser/#/R-GGA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70893 https://reactome.org/PathwayBrowser/#/R-GGA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70938 https://reactome.org/PathwayBrowser/#/R-GGA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70940 https://reactome.org/PathwayBrowser/#/R-GGA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70941 https://reactome.org/PathwayBrowser/#/R-GGA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70975 https://reactome.org/PathwayBrowser/#/R-GGA-70975 CS acetylates OA to citrate IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-70979 https://reactome.org/PathwayBrowser/#/R-GGA-70979 MDH2 dimer dehydrogenates MAL IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-71046 https://reactome.org/PathwayBrowser/#/R-GGA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71130 https://reactome.org/PathwayBrowser/#/R-GGA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71181 https://reactome.org/PathwayBrowser/#/R-GGA-71181 FAH cleaves 4FAA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71217 https://reactome.org/PathwayBrowser/#/R-GGA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71260 https://reactome.org/PathwayBrowser/#/R-GGA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71286 https://reactome.org/PathwayBrowser/#/R-GGA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71296 https://reactome.org/PathwayBrowser/#/R-GGA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-71401 https://reactome.org/PathwayBrowser/#/R-GGA-71401 OGDH dimer decarboxylates 2-OG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71670 https://reactome.org/PathwayBrowser/#/R-GGA-71670 PKM dephosphorylates PEP to PYR IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71682 https://reactome.org/PathwayBrowser/#/R-GGA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71691 https://reactome.org/PathwayBrowser/#/R-GGA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71707 https://reactome.org/PathwayBrowser/#/R-GGA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-71723 https://reactome.org/PathwayBrowser/#/R-GGA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71802 https://reactome.org/PathwayBrowser/#/R-GGA-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-71849 https://reactome.org/PathwayBrowser/#/R-GGA-71849 LDH tetramer reduces PYR to LACT IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73564 https://reactome.org/PathwayBrowser/#/R-GGA-73564 UMPS dimer decarboxylates OMP to UMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73580 https://reactome.org/PathwayBrowser/#/R-GGA-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73585 https://reactome.org/PathwayBrowser/#/R-GGA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73589 https://reactome.org/PathwayBrowser/#/R-GGA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73591 https://reactome.org/PathwayBrowser/#/R-GGA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73596 https://reactome.org/PathwayBrowser/#/R-GGA-73596 dCMP + H2O => dUMP + NH4+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73616 https://reactome.org/PathwayBrowser/#/R-GGA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73618 https://reactome.org/PathwayBrowser/#/R-GGA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73620 https://reactome.org/PathwayBrowser/#/R-GGA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73646 https://reactome.org/PathwayBrowser/#/R-GGA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73647 https://reactome.org/PathwayBrowser/#/R-GGA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Gallus gallus 15378 R-ALL-9668967 H+ [nucleoplasm] R-GGA-73666 https://reactome.org/PathwayBrowser/#/R-GGA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73792 https://reactome.org/PathwayBrowser/#/R-GGA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73794 https://reactome.org/PathwayBrowser/#/R-GGA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73805 https://reactome.org/PathwayBrowser/#/R-GGA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73806 https://reactome.org/PathwayBrowser/#/R-GGA-73806 AIR + CO2 => CAIR IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73810 https://reactome.org/PathwayBrowser/#/R-GGA-73810 FGAM + ATP => AIR + ADP + Pi IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73813 https://reactome.org/PathwayBrowser/#/R-GGA-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-73814 https://reactome.org/PathwayBrowser/#/R-GGA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-73912 https://reactome.org/PathwayBrowser/#/R-GGA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-73920 https://reactome.org/PathwayBrowser/#/R-GGA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-74255 https://reactome.org/PathwayBrowser/#/R-GGA-74255 Guanine + H2O => Xanthine + NH4+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus 15378 R-ALL-74722 H+ [endosome lumen] R-GGA-74723 https://reactome.org/PathwayBrowser/#/R-GGA-74723 Endosome acidification IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-74872 https://reactome.org/PathwayBrowser/#/R-GGA-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-749448 https://reactome.org/PathwayBrowser/#/R-GGA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-749452 https://reactome.org/PathwayBrowser/#/R-GGA-749452 The Ligand:GPCR:Gq complex dissociates IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-75851 https://reactome.org/PathwayBrowser/#/R-GGA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-75872 https://reactome.org/PathwayBrowser/#/R-GGA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-75883 https://reactome.org/PathwayBrowser/#/R-GGA-75883 DHRS7B reduces GO3P to HXDG3P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-75889 https://reactome.org/PathwayBrowser/#/R-GGA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77254 https://reactome.org/PathwayBrowser/#/R-GGA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77283 https://reactome.org/PathwayBrowser/#/R-GGA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77303 https://reactome.org/PathwayBrowser/#/R-GGA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77312 https://reactome.org/PathwayBrowser/#/R-GGA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77323 https://reactome.org/PathwayBrowser/#/R-GGA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77331 https://reactome.org/PathwayBrowser/#/R-GGA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-77342 https://reactome.org/PathwayBrowser/#/R-GGA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8850846 https://reactome.org/PathwayBrowser/#/R-GGA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8850854 https://reactome.org/PathwayBrowser/#/R-GGA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851089 https://reactome.org/PathwayBrowser/#/R-GGA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851110 https://reactome.org/PathwayBrowser/#/R-GGA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851129 https://reactome.org/PathwayBrowser/#/R-GGA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-8851225 https://reactome.org/PathwayBrowser/#/R-GGA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-8851234 https://reactome.org/PathwayBrowser/#/R-GGA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851356 https://reactome.org/PathwayBrowser/#/R-GGA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851396 https://reactome.org/PathwayBrowser/#/R-GGA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-GGA-8851494 https://reactome.org/PathwayBrowser/#/R-GGA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851538 https://reactome.org/PathwayBrowser/#/R-GGA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8851550 https://reactome.org/PathwayBrowser/#/R-GGA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8862137 https://reactome.org/PathwayBrowser/#/R-GGA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8863494 https://reactome.org/PathwayBrowser/#/R-GGA-8863494 ASICs bind STOML3, (STOM) IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-8863761 https://reactome.org/PathwayBrowser/#/R-GGA-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Gallus gallus 15378 R-ALL-9668967 H+ [nucleoplasm] R-GGA-8866601 https://reactome.org/PathwayBrowser/#/R-GGA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8869606 https://reactome.org/PathwayBrowser/#/R-GGA-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8869607 https://reactome.org/PathwayBrowser/#/R-GGA-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8869627 https://reactome.org/PathwayBrowser/#/R-GGA-8869627 NMRK2 phosphorylates NR to yield NMN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8869633 https://reactome.org/PathwayBrowser/#/R-GGA-8869633 NMRK1 phosphorylates NR to yield NMN IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8870346 https://reactome.org/PathwayBrowser/#/R-GGA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8875623 https://reactome.org/PathwayBrowser/#/R-GGA-8875623 SLC25A18,22 import L-Glu, H+ IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-8875623 https://reactome.org/PathwayBrowser/#/R-GGA-8875623 SLC25A18,22 import L-Glu, H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8876789 https://reactome.org/PathwayBrowser/#/R-GGA-8876789 CARNMT1 methylates CARN to Anserine IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-8878914 https://reactome.org/PathwayBrowser/#/R-GGA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-888548 https://reactome.org/PathwayBrowser/#/R-GGA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-888572 https://reactome.org/PathwayBrowser/#/R-GGA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-888577 https://reactome.org/PathwayBrowser/#/R-GGA-888577 Synthesis of GABA by GAD2 IEA Gallus gallus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-GGA-8933635 https://reactome.org/PathwayBrowser/#/R-GGA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8936442 https://reactome.org/PathwayBrowser/#/R-GGA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8938076 https://reactome.org/PathwayBrowser/#/R-GGA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8939959 https://reactome.org/PathwayBrowser/#/R-GGA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8940070 https://reactome.org/PathwayBrowser/#/R-GGA-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8942575 https://reactome.org/PathwayBrowser/#/R-GGA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-8952873 https://reactome.org/PathwayBrowser/#/R-GGA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-8954468 https://reactome.org/PathwayBrowser/#/R-GGA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-8955030 https://reactome.org/PathwayBrowser/#/R-GGA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8955760 https://reactome.org/PathwayBrowser/#/R-GGA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8955844 https://reactome.org/PathwayBrowser/#/R-GGA-8955844 RBKS phosphorylates ribose to R5P IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-8959719 https://reactome.org/PathwayBrowser/#/R-GGA-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9009950 https://reactome.org/PathwayBrowser/#/R-GGA-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9011595 https://reactome.org/PathwayBrowser/#/R-GGA-9011595 GSTZ1 dimer dehalogenates DCA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9012016 https://reactome.org/PathwayBrowser/#/R-GGA-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9012036 https://reactome.org/PathwayBrowser/#/R-GGA-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-9013198 https://reactome.org/PathwayBrowser/#/R-GGA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9024766 https://reactome.org/PathwayBrowser/#/R-GGA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15378 R-ALL-74722 H+ [endosome lumen] R-GGA-917811 https://reactome.org/PathwayBrowser/#/R-GGA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 15378 R-ALL-74722 H+ [endosome lumen] R-GGA-917841 https://reactome.org/PathwayBrowser/#/R-GGA-917841 Acidification of Tf:TfR1 containing endosome IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-937311 https://reactome.org/PathwayBrowser/#/R-GGA-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9619024 https://reactome.org/PathwayBrowser/#/R-GGA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-9645220 https://reactome.org/PathwayBrowser/#/R-GGA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-9650165 https://reactome.org/PathwayBrowser/#/R-GGA-9650165 ASIC trimers bind H+ IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9705713 https://reactome.org/PathwayBrowser/#/R-GGA-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9705714 https://reactome.org/PathwayBrowser/#/R-GGA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9709098 https://reactome.org/PathwayBrowser/#/R-GGA-9709098 DHFR dimer reduces FOLA to DHF IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9727347 https://reactome.org/PathwayBrowser/#/R-GGA-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9727349 https://reactome.org/PathwayBrowser/#/R-GGA-9727349 XDH dehydrogenates xanthine to form urate IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9731228 https://reactome.org/PathwayBrowser/#/R-GGA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9731590 https://reactome.org/PathwayBrowser/#/R-GGA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9731613 https://reactome.org/PathwayBrowser/#/R-GGA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9731632 https://reactome.org/PathwayBrowser/#/R-GGA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9731661 https://reactome.org/PathwayBrowser/#/R-GGA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9748945 https://reactome.org/PathwayBrowser/#/R-GGA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9748957 https://reactome.org/PathwayBrowser/#/R-GGA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9748979 https://reactome.org/PathwayBrowser/#/R-GGA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9748983 https://reactome.org/PathwayBrowser/#/R-GGA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9748991 https://reactome.org/PathwayBrowser/#/R-GGA-9748991 XDH oxidises 6MP to 6TU IEA Gallus gallus 15378 R-ALL-351626 H+ [extracellular region] R-GGA-9749609 https://reactome.org/PathwayBrowser/#/R-GGA-9749609 BCHE hydrolyzes ASA- IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9749647 https://reactome.org/PathwayBrowser/#/R-GGA-9749647 CES2 hydrolyzes ASA- IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9749792 https://reactome.org/PathwayBrowser/#/R-GGA-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9755937 https://reactome.org/PathwayBrowser/#/R-GGA-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756134 https://reactome.org/PathwayBrowser/#/R-GGA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756156 https://reactome.org/PathwayBrowser/#/R-GGA-9756156 UGT1A3 lactonizes ATV to ATVL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756177 https://reactome.org/PathwayBrowser/#/R-GGA-9756177 PON1,3 hydrolyse ATVL to ATV IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9756183 https://reactome.org/PathwayBrowser/#/R-GGA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-975629 https://reactome.org/PathwayBrowser/#/R-GGA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9757706 https://reactome.org/PathwayBrowser/#/R-GGA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9758661 https://reactome.org/PathwayBrowser/#/R-GGA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9759259 https://reactome.org/PathwayBrowser/#/R-GGA-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9759549 https://reactome.org/PathwayBrowser/#/R-GGA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9760094 https://reactome.org/PathwayBrowser/#/R-GGA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-977301 https://reactome.org/PathwayBrowser/#/R-GGA-977301 Histidine is decarboxylated to histamine IEA Gallus gallus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-GGA-977317 https://reactome.org/PathwayBrowser/#/R-GGA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9773976 https://reactome.org/PathwayBrowser/#/R-GGA-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9794270 https://reactome.org/PathwayBrowser/#/R-GGA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Gallus gallus 15378 R-ALL-9668967 H+ [nucleoplasm] R-GGA-9825790 https://reactome.org/PathwayBrowser/#/R-GGA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9837337 https://reactome.org/PathwayBrowser/#/R-GGA-9837337 DCAKD phosphorylates DP-CoA IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9843721 https://reactome.org/PathwayBrowser/#/R-GGA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9844587 https://reactome.org/PathwayBrowser/#/R-GGA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9844860 https://reactome.org/PathwayBrowser/#/R-GGA-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9845538 https://reactome.org/PathwayBrowser/#/R-GGA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9845587 https://reactome.org/PathwayBrowser/#/R-GGA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9846305 https://reactome.org/PathwayBrowser/#/R-GGA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9846477 https://reactome.org/PathwayBrowser/#/R-GGA-9846477 A4GALT transfers galactose to LacCer IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9846501 https://reactome.org/PathwayBrowser/#/R-GGA-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Gallus gallus 15378 R-ALL-425969 H+ [Golgi lumen] R-GGA-9851347 https://reactome.org/PathwayBrowser/#/R-GGA-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9853499 https://reactome.org/PathwayBrowser/#/R-GGA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9854415 https://reactome.org/PathwayBrowser/#/R-GGA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9856871 https://reactome.org/PathwayBrowser/#/R-GGA-9856871 MDH1 reduces OA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9858321 https://reactome.org/PathwayBrowser/#/R-GGA-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9858589 https://reactome.org/PathwayBrowser/#/R-GGA-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9858590 https://reactome.org/PathwayBrowser/#/R-GGA-9858590 DLST transfers glutaryl to CoA IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9859148 https://reactome.org/PathwayBrowser/#/R-GGA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9859172 https://reactome.org/PathwayBrowser/#/R-GGA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9861616 https://reactome.org/PathwayBrowser/#/R-GGA-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9861642 https://reactome.org/PathwayBrowser/#/R-GGA-9861642 NEK1 phosphorylates ME1 IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9861660 https://reactome.org/PathwayBrowser/#/R-GGA-9861660 ME1 tetramer decarboxylates OA to PYR IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9861734 https://reactome.org/PathwayBrowser/#/R-GGA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9864415 https://reactome.org/PathwayBrowser/#/R-GGA-9864415 AAC1 imports a proton IEA Gallus gallus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-GGA-9864415 https://reactome.org/PathwayBrowser/#/R-GGA-9864415 AAC1 imports a proton IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9909159 https://reactome.org/PathwayBrowser/#/R-GGA-9909159 HK1 phosphorylates Mannose to Man6P IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-GGA-9929439 https://reactome.org/PathwayBrowser/#/R-GGA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9935449 https://reactome.org/PathwayBrowser/#/R-GGA-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Gallus gallus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-GGA-9935469 https://reactome.org/PathwayBrowser/#/R-GGA-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Gallus gallus 15378 R-ALL-70106 H+ [cytosol] R-GGA-9937295 https://reactome.org/PathwayBrowser/#/R-GGA-9937295 SRD5A3 reduces polyprenal to dolichal IEA Gallus gallus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-109339 https://reactome.org/PathwayBrowser/#/R-HSA-109339 Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-109342 https://reactome.org/PathwayBrowser/#/R-HSA-109342 Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-109343 https://reactome.org/PathwayBrowser/#/R-HSA-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-111215 https://reactome.org/PathwayBrowser/#/R-HSA-111215 PRPS1 dimer pyrophosphorylates R5P using dATP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-111524 https://reactome.org/PathwayBrowser/#/R-HSA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-111883 https://reactome.org/PathwayBrowser/#/R-HSA-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-1222353 https://reactome.org/PathwayBrowser/#/R-HSA-1222353 Protonation of superoxide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222384 https://reactome.org/PathwayBrowser/#/R-HSA-1222384 Glutathione scavenges nitrosyl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222399 https://reactome.org/PathwayBrowser/#/R-HSA-1222399 Iron is reduced and separates from mycobactin IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222412 https://reactome.org/PathwayBrowser/#/R-HSA-1222412 LpdC dimer reactivates DlaT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222485 https://reactome.org/PathwayBrowser/#/R-HSA-1222485 TrxB reactivates TrxA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222516 https://reactome.org/PathwayBrowser/#/R-HSA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-1222516 https://reactome.org/PathwayBrowser/#/R-HSA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222583 https://reactome.org/PathwayBrowser/#/R-HSA-1222583 MscR reduces nitrosomycothiol to ammonia TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1222594 https://reactome.org/PathwayBrowser/#/R-HSA-1222594 Mycothiol scavenges nitrosyl TAS Homo sapiens 15378 R-ALL-2000349 H+ [phagolysosome] R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1237045 https://reactome.org/PathwayBrowser/#/R-HSA-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1237047 https://reactome.org/PathwayBrowser/#/R-HSA-1237047 CA4:Zn2+ hydrates CO2 to HCO3- TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1237059 https://reactome.org/PathwayBrowser/#/R-HSA-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1237081 https://reactome.org/PathwayBrowser/#/R-HSA-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1475017 https://reactome.org/PathwayBrowser/#/R-HSA-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1475022 https://reactome.org/PathwayBrowser/#/R-HSA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-1475025 https://reactome.org/PathwayBrowser/#/R-HSA-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1475026 https://reactome.org/PathwayBrowser/#/R-HSA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-1475028 https://reactome.org/PathwayBrowser/#/R-HSA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-1475032 https://reactome.org/PathwayBrowser/#/R-HSA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1475435 https://reactome.org/PathwayBrowser/#/R-HSA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1475436 https://reactome.org/PathwayBrowser/#/R-HSA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1497794 https://reactome.org/PathwayBrowser/#/R-HSA-1497794 Salvage - BH2 is reduced to BH4 by DHFR IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1497869 https://reactome.org/PathwayBrowser/#/R-HSA-1497869 Salvage - Sepiapterin is reduced to q-BH2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-158609 https://reactome.org/PathwayBrowser/#/R-HSA-158609 TPMT transfers CH3 from AdoMet to 6MP TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-159790 https://reactome.org/PathwayBrowser/#/R-HSA-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-1605797 https://reactome.org/PathwayBrowser/#/R-HSA-1605797 SMPD1 hydrolyzes SPHM TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1606273 https://reactome.org/PathwayBrowser/#/R-HSA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1606288 https://reactome.org/PathwayBrowser/#/R-HSA-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-1606807 https://reactome.org/PathwayBrowser/#/R-HSA-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-1614362 https://reactome.org/PathwayBrowser/#/R-HSA-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1614567 https://reactome.org/PathwayBrowser/#/R-HSA-1614567 Excess homocysteine yields homolanthionine and H2S TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1614591 https://reactome.org/PathwayBrowser/#/R-HSA-1614591 Excess cysteine yields lanthionine and H2S TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1614614 https://reactome.org/PathwayBrowser/#/R-HSA-1614614 Cysteine is degraded to pyruvate and H2S TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1614631 https://reactome.org/PathwayBrowser/#/R-HSA-1614631 Homocysteine is degraded to oxobutanoate and H2S TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 15378 R-ALL-1614597 H+ [mitochondrial inner membrane] R-HSA-1614665 https://reactome.org/PathwayBrowser/#/R-HSA-1614665 SQR oxidizes sulfide to bound persulfide IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-162730 https://reactome.org/PathwayBrowser/#/R-HSA-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-163120 https://reactome.org/PathwayBrowser/#/R-HSA-163120 Disassociation of Telomerase RNP and the Chromosome End TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-163217 https://reactome.org/PathwayBrowser/#/R-HSA-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-163672 https://reactome.org/PathwayBrowser/#/R-HSA-163672 Phosphorylation of ChREBP at Thr(653) by PKA IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-163676 https://reactome.org/PathwayBrowser/#/R-HSA-163676 Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA IEA Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-163691 https://reactome.org/PathwayBrowser/#/R-HSA-163691 Phosphorylation of ChREBP at Serine 556 by AMPK IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-163773 https://reactome.org/PathwayBrowser/#/R-HSA-163773 PKA tetramer:cAMP phosphorylates PF2K-Pase IEA Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-1638104 https://reactome.org/PathwayBrowser/#/R-HSA-1638104 UGCG transfers glucose to ceramide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1638845 https://reactome.org/PathwayBrowser/#/R-HSA-1638845 CERK phosphorylates CERA to form C1P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1640164 https://reactome.org/PathwayBrowser/#/R-HSA-1640164 ENPP7 hydrolyzes sphingomyelin TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-164151 https://reactome.org/PathwayBrowser/#/R-HSA-164151 LKB1 phosphorylates the alpha subunit of AMPK heterotrimer IEA Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-164651 https://reactome.org/PathwayBrowser/#/R-HSA-164651 Electron transfer from ubiquinol to cytochrome c of complex III TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-164834 https://reactome.org/PathwayBrowser/#/R-HSA-164834 Enzyme-bound ATP is released TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-164834 https://reactome.org/PathwayBrowser/#/R-HSA-164834 Enzyme-bound ATP is released TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1655443 https://reactome.org/PathwayBrowser/#/R-HSA-1655443 PXKLP-K305-CSAD decarboxylates 3-sulfinoalanine to hypotaurine IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-1655879 https://reactome.org/PathwayBrowser/#/R-HSA-1655879 Thiosulfate can transfer its sulfur atom to glutathione TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-166219 https://reactome.org/PathwayBrowser/#/R-HSA-166219 FA anion picks up a proton TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-166223 https://reactome.org/PathwayBrowser/#/R-HSA-166223 The proton is delivered to the matrix side TAS Homo sapiens 15378 R-ALL-9631150 H+ [endolysosome lumen] R-HSA-1678920 https://reactome.org/PathwayBrowser/#/R-HSA-1678920 TLR processing at low pH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-168299 https://reactome.org/PathwayBrowser/#/R-HSA-168299 Ribonucleoprotein release from M1 proteins TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-168299 https://reactome.org/PathwayBrowser/#/R-HSA-168299 Ribonucleoprotein release from M1 proteins TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-168313 https://reactome.org/PathwayBrowser/#/R-HSA-168313 Virion-associated M2 protein mediated ion infusion TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-169270 https://reactome.org/PathwayBrowser/#/R-HSA-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 UCP1 imports a proton TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-170026 https://reactome.org/PathwayBrowser/#/R-HSA-170026 UCP1 imports a proton TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-173597 https://reactome.org/PathwayBrowser/#/R-HSA-173597 UDP-glucose is oxidised to UDP-glucuronate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-174389 https://reactome.org/PathwayBrowser/#/R-HSA-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-174392 https://reactome.org/PathwayBrowser/#/R-HSA-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-174438 https://reactome.org/PathwayBrowser/#/R-HSA-174438 Formation of the Flap Intermediate on the C-strand TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-175993 https://reactome.org/PathwayBrowser/#/R-HSA-175993 HNMT transfers CH3 group from AdoMet to Hist TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-189425 https://reactome.org/PathwayBrowser/#/R-HSA-189425 UROD decarboxylates URO3 to COPRO3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-189439 https://reactome.org/PathwayBrowser/#/R-HSA-189439 ALAD condenses 2 dALAs to form PBG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-189442 https://reactome.org/PathwayBrowser/#/R-HSA-189442 ALAS condenses SUCC-CoA and Gly to form dALA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-189465 https://reactome.org/PathwayBrowser/#/R-HSA-189465 FECH binds Fe2+ to PRIN9 to form heme TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-190182 https://reactome.org/PathwayBrowser/#/R-HSA-190182 UROD decarboxylates URO1 to COPRO1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191323 https://reactome.org/PathwayBrowser/#/R-HSA-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191352 https://reactome.org/PathwayBrowser/#/R-HSA-191352 HMGCR dimer reduces bHMG-CoA to MVA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191402 https://reactome.org/PathwayBrowser/#/R-HSA-191402 Reduction of presqualene diphosphate to form squalene TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192033 https://reactome.org/PathwayBrowser/#/R-HSA-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192036 https://reactome.org/PathwayBrowser/#/R-HSA-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-192042 https://reactome.org/PathwayBrowser/#/R-HSA-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192067 https://reactome.org/PathwayBrowser/#/R-HSA-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192097 https://reactome.org/PathwayBrowser/#/R-HSA-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192160 https://reactome.org/PathwayBrowser/#/R-HSA-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193064 https://reactome.org/PathwayBrowser/#/R-HSA-193064 HSD17B3-like proteins reducde ANDST to TEST TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193073 https://reactome.org/PathwayBrowser/#/R-HSA-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-193455 https://reactome.org/PathwayBrowser/#/R-HSA-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193497 https://reactome.org/PathwayBrowser/#/R-HSA-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-193508 https://reactome.org/PathwayBrowser/#/R-HSA-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193746 https://reactome.org/PathwayBrowser/#/R-HSA-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193755 https://reactome.org/PathwayBrowser/#/R-HSA-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193758 https://reactome.org/PathwayBrowser/#/R-HSA-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193781 https://reactome.org/PathwayBrowser/#/R-HSA-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193789 https://reactome.org/PathwayBrowser/#/R-HSA-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193800 https://reactome.org/PathwayBrowser/#/R-HSA-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193816 https://reactome.org/PathwayBrowser/#/R-HSA-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193821 https://reactome.org/PathwayBrowser/#/R-HSA-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193824 https://reactome.org/PathwayBrowser/#/R-HSA-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193841 https://reactome.org/PathwayBrowser/#/R-HSA-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194023 https://reactome.org/PathwayBrowser/#/R-HSA-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194632 https://reactome.org/PathwayBrowser/#/R-HSA-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194642 https://reactome.org/PathwayBrowser/#/R-HSA-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-ALL-194688 H+ [nuclear envelope] R-HSA-194674 https://reactome.org/PathwayBrowser/#/R-HSA-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194689 https://reactome.org/PathwayBrowser/#/R-HSA-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194698 https://reactome.org/PathwayBrowser/#/R-HSA-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-194718 https://reactome.org/PathwayBrowser/#/R-HSA-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196060 https://reactome.org/PathwayBrowser/#/R-HSA-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196350 https://reactome.org/PathwayBrowser/#/R-HSA-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196372 https://reactome.org/PathwayBrowser/#/R-HSA-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196402 https://reactome.org/PathwayBrowser/#/R-HSA-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196417 https://reactome.org/PathwayBrowser/#/R-HSA-196417 Reduction of desmosterol to cholesterol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196753 https://reactome.org/PathwayBrowser/#/R-HSA-196753 2xPPCS ligates PPanK with Cys TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196754 https://reactome.org/PathwayBrowser/#/R-HSA-196754 COASY transfers an adenylyl group from ATP to PPANT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196773 https://reactome.org/PathwayBrowser/#/R-HSA-196773 COASY phosphorylates DP-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196840 https://reactome.org/PathwayBrowser/#/R-HSA-196840 3xPPCDC:3FMN decarboxylates PPC TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196857 https://reactome.org/PathwayBrowser/#/R-HSA-196857 PANK2 phosphorylates PanK TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196929 https://reactome.org/PathwayBrowser/#/R-HSA-196929 FLAD1 phosphorylates FMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196955 https://reactome.org/PathwayBrowser/#/R-HSA-196955 2xENPP1 hydrolyzes FAD to FMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-196964 https://reactome.org/PathwayBrowser/#/R-HSA-196964 RFK:Mg2+ phosphorylates RIB TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197187 https://reactome.org/PathwayBrowser/#/R-HSA-197187 ACS transforms to QUIN non-enzymatically TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197198 https://reactome.org/PathwayBrowser/#/R-HSA-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197235 https://reactome.org/PathwayBrowser/#/R-HSA-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197250 https://reactome.org/PathwayBrowser/#/R-HSA-197250 NAMPT transfers PRIB to NAM to form NAMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197268 https://reactome.org/PathwayBrowser/#/R-HSA-197268 QPRT transfers PRIB to QUIN to form NAMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197271 https://reactome.org/PathwayBrowser/#/R-HSA-197271 NADSYN1 hexamer amidates NAAD to NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197963 https://reactome.org/PathwayBrowser/#/R-HSA-197963 DHFR2 reduces FOLA to DHF TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-197972 https://reactome.org/PathwayBrowser/#/R-HSA-197972 DHF is reduced to tetrahydrofolate (THF) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-198824 https://reactome.org/PathwayBrowser/#/R-HSA-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-199203 https://reactome.org/PathwayBrowser/#/R-HSA-199203 PANK1/3 phosphorylate PanK TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200423 https://reactome.org/PathwayBrowser/#/R-HSA-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-200474 https://reactome.org/PathwayBrowser/#/R-HSA-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-200512 https://reactome.org/PathwayBrowser/#/R-HSA-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200555 https://reactome.org/PathwayBrowser/#/R-HSA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200644 https://reactome.org/PathwayBrowser/#/R-HSA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200646 https://reactome.org/PathwayBrowser/#/R-HSA-200646 Cytosolic folate export across the plasma membrane TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-200646 https://reactome.org/PathwayBrowser/#/R-HSA-200646 Cytosolic folate export across the plasma membrane TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200676 https://reactome.org/PathwayBrowser/#/R-HSA-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200718 https://reactome.org/PathwayBrowser/#/R-HSA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-200729 https://reactome.org/PathwayBrowser/#/R-HSA-200729 SLC46A1 transports FOLA from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-200729 https://reactome.org/PathwayBrowser/#/R-HSA-200729 SLC46A1 transports FOLA from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-202111 https://reactome.org/PathwayBrowser/#/R-HSA-202111 AKT1 phosphorylates eNOS TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-203611 https://reactome.org/PathwayBrowser/#/R-HSA-203611 N-myristoylation of eNOS IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-203613 https://reactome.org/PathwayBrowser/#/R-HSA-203613 Depalmitoylation of eNOS TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-203946 https://reactome.org/PathwayBrowser/#/R-HSA-203946 PDK isozymes phosphorylate PDHC subunit E1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-204617 https://reactome.org/PathwayBrowser/#/R-HSA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-204647 https://reactome.org/PathwayBrowser/#/R-HSA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209772 https://reactome.org/PathwayBrowser/#/R-HSA-209772 Thyroxine is deiodinated to triiodothyronine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209821 https://reactome.org/PathwayBrowser/#/R-HSA-209821 Methylation of N-acetyl-5-HT to form melatonin TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-209903 https://reactome.org/PathwayBrowser/#/R-HSA-209903 Noradrenaline is converted to adrenaline TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-209973 https://reactome.org/PathwayBrowser/#/R-HSA-209973 Tyrosine is diiodinated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-210404 https://reactome.org/PathwayBrowser/#/R-HSA-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161187 https://reactome.org/PathwayBrowser/#/R-HSA-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161549 https://reactome.org/PathwayBrowser/#/R-HSA-2161549 PGH2 is reduced to PGF2a by AKR1C3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161567 https://reactome.org/PathwayBrowser/#/R-HSA-2161567 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161614 https://reactome.org/PathwayBrowser/#/R-HSA-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161651 https://reactome.org/PathwayBrowser/#/R-HSA-2161651 PGE2 is converted to PGF2a by CBR1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161662 https://reactome.org/PathwayBrowser/#/R-HSA-2161662 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161692 https://reactome.org/PathwayBrowser/#/R-HSA-2161692 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1 IEA Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-2161732 https://reactome.org/PathwayBrowser/#/R-HSA-2161732 TXB2 is converted to 11dh-TXB2 by TXDH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161776 https://reactome.org/PathwayBrowser/#/R-HSA-2161776 5S-HETE is oxidised to 5-oxoETE by 5-HEDH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161779 https://reactome.org/PathwayBrowser/#/R-HSA-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161789 https://reactome.org/PathwayBrowser/#/R-HSA-2161789 15S-HETE is oxidised to 15-oxoETE by 15-HEDH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161844 https://reactome.org/PathwayBrowser/#/R-HSA-2161844 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2162078 https://reactome.org/PathwayBrowser/#/R-HSA-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162186 https://reactome.org/PathwayBrowser/#/R-HSA-2162186 COQ3 methylates DeMQ10H2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162188 https://reactome.org/PathwayBrowser/#/R-HSA-2162188 COQ5 methylates MDMQ10H2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162193 https://reactome.org/PathwayBrowser/#/R-HSA-2162193 COQ3 methylates DHDB TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2162195 https://reactome.org/PathwayBrowser/#/R-HSA-2162195 COQ4 decarboxylates MHDB TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2395512 https://reactome.org/PathwayBrowser/#/R-HSA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2395517 https://reactome.org/PathwayBrowser/#/R-HSA-2395517 NADPH transfers electrons to FDXR TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395818 https://reactome.org/PathwayBrowser/#/R-HSA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395849 https://reactome.org/PathwayBrowser/#/R-HSA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395869 https://reactome.org/PathwayBrowser/#/R-HSA-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395872 https://reactome.org/PathwayBrowser/#/R-HSA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395873 https://reactome.org/PathwayBrowser/#/R-HSA-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395876 https://reactome.org/PathwayBrowser/#/R-HSA-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395879 https://reactome.org/PathwayBrowser/#/R-HSA-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2395965 https://reactome.org/PathwayBrowser/#/R-HSA-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP TAS Homo sapiens 15378 R-ALL-2429673 H+ [early endosome] R-HSA-2404140 https://reactome.org/PathwayBrowser/#/R-HSA-2404140 NREH hydrolyses atREs to atROL and FAs TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408524 https://reactome.org/PathwayBrowser/#/R-HSA-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408526 https://reactome.org/PathwayBrowser/#/R-HSA-2408526 tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408542 https://reactome.org/PathwayBrowser/#/R-HSA-2408542 GSSeSG is reduced to GSSeH and GSH by GSR IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408544 https://reactome.org/PathwayBrowser/#/R-HSA-2408544 AdoSeMet is converted to AdeSeHCys by MetTrans(1) IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408548 https://reactome.org/PathwayBrowser/#/R-HSA-2408548 PAPSe is reduced to SeO3(2-) by PAPSe reductase IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408556 https://reactome.org/PathwayBrowser/#/R-HSA-2408556 SeO3(2-) combines with GSH to form GSSeSG and GSSG IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2408558 https://reactome.org/PathwayBrowser/#/R-HSA-2408558 SeO3(2-) is reduced to H2Se by TXNRD1 IEA Homo sapiens 15378 R-ALL-2429673 H+ [early endosome] R-HSA-2429643 https://reactome.org/PathwayBrowser/#/R-HSA-2429643 NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2453833 https://reactome.org/PathwayBrowser/#/R-HSA-2453833 RPE65 isomero-hydrolyses atREs to 11cROL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2454081 https://reactome.org/PathwayBrowser/#/R-HSA-2454081 RDH5 oxidises 11cROL to 11cRAL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2464803 https://reactome.org/PathwayBrowser/#/R-HSA-2464803 RDH8 reduces atRAL to atROL IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2464822 https://reactome.org/PathwayBrowser/#/R-HSA-2464822 RDH12 reduces atRAL to atROL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2465921 https://reactome.org/PathwayBrowser/#/R-HSA-2465921 11cRDH oxidises 11cROL to 11cRAL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2465940 https://reactome.org/PathwayBrowser/#/R-HSA-2465940 atRAL is reduced to atROL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2465941 https://reactome.org/PathwayBrowser/#/R-HSA-2465941 A REH hydrolyses 11cRE to 11cROL IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2466861 https://reactome.org/PathwayBrowser/#/R-HSA-2466861 Defective RDH12 does not reduce atRAL to atROL TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-2509793 https://reactome.org/PathwayBrowser/#/R-HSA-2509793 NUDT16 hydrolyses dIDP to dIMP TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-2509816 https://reactome.org/PathwayBrowser/#/R-HSA-2509816 NUDT16 hydrolyses IDP to IMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2509827 https://reactome.org/PathwayBrowser/#/R-HSA-2509827 ITPA hydrolyses ITP to IMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2509831 https://reactome.org/PathwayBrowser/#/R-HSA-2509831 ITPA hydrolyses XTP to XMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2509838 https://reactome.org/PathwayBrowser/#/R-HSA-2509838 ITPA hydrolyses dITP to dIMP TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-2534378 https://reactome.org/PathwayBrowser/#/R-HSA-2534378 Hv1 Mediated H+ Permeability TAS Homo sapiens 15378 R-ALL-1132304 H+ [cytoplasm] R-HSA-2534378 https://reactome.org/PathwayBrowser/#/R-HSA-2534378 Hv1 Mediated H+ Permeability TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2564824 https://reactome.org/PathwayBrowser/#/R-HSA-2564824 NADPH reduces NDOR1:CIAPIN1 IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-HSA-264615 https://reactome.org/PathwayBrowser/#/R-HSA-264615 Loading of acetylcholine in synaptic vesicles TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-266070 https://reactome.org/PathwayBrowser/#/R-HSA-266070 LTC4 is exported from the cytosol by ABCC1 TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-2671885 https://reactome.org/PathwayBrowser/#/R-HSA-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2730692 https://reactome.org/PathwayBrowser/#/R-HSA-2730692 CLCN4/5/6 exchange Cl- for H+ TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-2730692 https://reactome.org/PathwayBrowser/#/R-HSA-2730692 CLCN4/5/6 exchange Cl- for H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2730959 https://reactome.org/PathwayBrowser/#/R-HSA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-2730959 https://reactome.org/PathwayBrowser/#/R-HSA-2730959 CLCN7:OSTM1 exchanges Cl- for H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2731002 https://reactome.org/PathwayBrowser/#/R-HSA-2731002 CLCN3 exchanges Cl- for H+ IEA Homo sapiens 15378 R-ALL-425999 H+ [late endosome lumen] R-HSA-2731002 https://reactome.org/PathwayBrowser/#/R-HSA-2731002 CLCN3 exchanges Cl- for H+ IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2855252 https://reactome.org/PathwayBrowser/#/R-HSA-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-2872444 https://reactome.org/PathwayBrowser/#/R-HSA-2872444 SLC9B1/C2 exchange Na+ for H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-2872444 https://reactome.org/PathwayBrowser/#/R-HSA-2872444 SLC9B1/C2 exchange Na+ for H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-2872463 https://reactome.org/PathwayBrowser/#/R-HSA-2872463 SLC9C1 exchanges Na+ for H+ IEA Homo sapiens 15378 R-ALL-2872447 H+ [sperm flagellum] R-HSA-2872463 https://reactome.org/PathwayBrowser/#/R-HSA-2872463 SLC9C1 exchanges Na+ for H+ IEA Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-2889070 https://reactome.org/PathwayBrowser/#/R-HSA-2889070 SLC9B2 exchanges Na+ for H+ TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-2889070 https://reactome.org/PathwayBrowser/#/R-HSA-2889070 SLC9B2 exchanges Na+ for H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3095889 https://reactome.org/PathwayBrowser/#/R-HSA-3095889 MMACHC dealkylates RCbl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3149518 https://reactome.org/PathwayBrowser/#/R-HSA-3149518 MTRR reduces cob(II)alamin to meCbl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3149519 https://reactome.org/PathwayBrowser/#/R-HSA-3149519 MMACHC decyanates CNCbl TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-3159253 https://reactome.org/PathwayBrowser/#/R-HSA-3159253 MMAB adenosylates cob(I)alamin TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3318576 https://reactome.org/PathwayBrowser/#/R-HSA-3318576 Defective MMACHC does not reduce Cbl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3318590 https://reactome.org/PathwayBrowser/#/R-HSA-3318590 Defective MMACHC does not decyanate CNCbl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322001 https://reactome.org/PathwayBrowser/#/R-HSA-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322003 https://reactome.org/PathwayBrowser/#/R-HSA-3322003 Autoglucosylation of GYG1 complexed with GYS1-b TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322009 https://reactome.org/PathwayBrowser/#/R-HSA-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322014 https://reactome.org/PathwayBrowser/#/R-HSA-3322014 Autoglucosylation of GYG2 complexed with GYS2-a TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322019 https://reactome.org/PathwayBrowser/#/R-HSA-3322019 Autoglucosylation of GYG2 complexed with GYS2-b TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322025 https://reactome.org/PathwayBrowser/#/R-HSA-3322025 Autoglucosylation of GYG1 complexed with GYS1-a TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3322041 https://reactome.org/PathwayBrowser/#/R-HSA-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-3323050 https://reactome.org/PathwayBrowser/#/R-HSA-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-3323079 https://reactome.org/PathwayBrowser/#/R-HSA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-349520 https://reactome.org/PathwayBrowser/#/R-HSA-349520 Re-acidification of acetylcholine transport vesicles TAS Homo sapiens 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-HSA-349520 https://reactome.org/PathwayBrowser/#/R-HSA-349520 Re-acidification of acetylcholine transport vesicles TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-350869 https://reactome.org/PathwayBrowser/#/R-HSA-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-350901 https://reactome.org/PathwayBrowser/#/R-HSA-350901 Iodide is organified TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-352174 https://reactome.org/PathwayBrowser/#/R-HSA-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-352182 https://reactome.org/PathwayBrowser/#/R-HSA-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-3560789 https://reactome.org/PathwayBrowser/#/R-HSA-3560789 Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-372342 https://reactome.org/PathwayBrowser/#/R-HSA-372342 MPC1:MPC2 imports PYR, H+ to mitochondrial matrix IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-372448 https://reactome.org/PathwayBrowser/#/R-HSA-372448 SLC25A12,13 exchange L-Glu and L-Asp TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-373867 https://reactome.org/PathwayBrowser/#/R-HSA-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-373875 https://reactome.org/PathwayBrowser/#/R-HSA-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 15378 R-ALL-374900 H+ [clathrin-sculpted monoamine transport vesicle lumen] R-HSA-374916 https://reactome.org/PathwayBrowser/#/R-HSA-374916 Re-acidification of clathrin sculpted monoamine transport vesicle lumen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-375405 https://reactome.org/PathwayBrowser/#/R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-375405 https://reactome.org/PathwayBrowser/#/R-HSA-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-375417 https://reactome.org/PathwayBrowser/#/R-HSA-375417 SLC36A1-mediated uptake of glycine, proline, and alanine TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3780994 https://reactome.org/PathwayBrowser/#/R-HSA-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-3781024 https://reactome.org/PathwayBrowser/#/R-HSA-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-379048 https://reactome.org/PathwayBrowser/#/R-HSA-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-380608 https://reactome.org/PathwayBrowser/#/R-HSA-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-389540 https://reactome.org/PathwayBrowser/#/R-HSA-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-389550 https://reactome.org/PathwayBrowser/#/R-HSA-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-389609 https://reactome.org/PathwayBrowser/#/R-HSA-389609 ALDH3A2-2 oxidizes pristanal to pristanate TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-389826 https://reactome.org/PathwayBrowser/#/R-HSA-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-389995 https://reactome.org/PathwayBrowser/#/R-HSA-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-390251 https://reactome.org/PathwayBrowser/#/R-HSA-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-390304 https://reactome.org/PathwayBrowser/#/R-HSA-390304 acetyl-CoA + H2O => acetate + CoASH + H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-390393 https://reactome.org/PathwayBrowser/#/R-HSA-390393 Peroxisomal uptake of very long-chain fatty acyl CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-390425 https://reactome.org/PathwayBrowser/#/R-HSA-390425 FAR1 reduces PalmCoA to HXOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-390438 https://reactome.org/PathwayBrowser/#/R-HSA-390438 FAR2 reduces PalmCoA to HXOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-418365 https://reactome.org/PathwayBrowser/#/R-HSA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen TAS Homo sapiens 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-HSA-418365 https://reactome.org/PathwayBrowser/#/R-HSA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-425577 https://reactome.org/PathwayBrowser/#/R-HSA-425577 Na+-driven Cl-/HCO3- exchanger transport TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-425965 https://reactome.org/PathwayBrowser/#/R-HSA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane TAS Homo sapiens 15378 R-ALL-425999 H+ [late endosome lumen] R-HSA-425965 https://reactome.org/PathwayBrowser/#/R-HSA-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-425983 https://reactome.org/PathwayBrowser/#/R-HSA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 15378 R-ALL-425978 H+ [early endosome lumen] R-HSA-425983 https://reactome.org/PathwayBrowser/#/R-HSA-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-425994 https://reactome.org/PathwayBrowser/#/R-HSA-425994 Na+/H+ exchanger transport (at cell membrane) TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-425994 https://reactome.org/PathwayBrowser/#/R-HSA-425994 Na+/H+ exchanger transport (at cell membrane) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-426015 https://reactome.org/PathwayBrowser/#/R-HSA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-426015 https://reactome.org/PathwayBrowser/#/R-HSA-426015 Na+/H+ exchanger transport (at trans-golgi membrane) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-426043 https://reactome.org/PathwayBrowser/#/R-HSA-426043 2-AG hydrolysis to arachidonate by MAGL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-427555 https://reactome.org/PathwayBrowser/#/R-HSA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-427555 https://reactome.org/PathwayBrowser/#/R-HSA-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-427910 https://reactome.org/PathwayBrowser/#/R-HSA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-427910 https://reactome.org/PathwayBrowser/#/R-HSA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-427998 https://reactome.org/PathwayBrowser/#/R-HSA-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-428007 https://reactome.org/PathwayBrowser/#/R-HSA-428007 Proton-coupled histidine and di-peptide cotransport TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-428015 https://reactome.org/PathwayBrowser/#/R-HSA-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428052 https://reactome.org/PathwayBrowser/#/R-HSA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 15378 R-ALL-428548 H+ [synaptic vesicle] R-HSA-428052 https://reactome.org/PathwayBrowser/#/R-HSA-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428123 https://reactome.org/PathwayBrowser/#/R-HSA-428123 KDSR reduces 3-ketosphingoid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428127 https://reactome.org/PathwayBrowser/#/R-HSA-428127 SPTLC complexes transfer acyl-CoA onto serine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428185 https://reactome.org/PathwayBrowser/#/R-HSA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428273 https://reactome.org/PathwayBrowser/#/R-HSA-428273 SPHK1 phosphorylates sphingoid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428585 https://reactome.org/PathwayBrowser/#/R-HSA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-428585 https://reactome.org/PathwayBrowser/#/R-HSA-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-428625 https://reactome.org/PathwayBrowser/#/R-HSA-428625 Vesicular inhibitory amino acid transport TAS Homo sapiens 15378 R-ALL-428548 H+ [synaptic vesicle] R-HSA-428625 https://reactome.org/PathwayBrowser/#/R-HSA-428625 Vesicular inhibitory amino acid transport TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-429016 https://reactome.org/PathwayBrowser/#/R-HSA-429016 ALOX5 is phosphorylated by MAPKAP2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-429101 https://reactome.org/PathwayBrowser/#/R-HSA-429101 HMIT co-transports myo-inositol with a proton TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-429101 https://reactome.org/PathwayBrowser/#/R-HSA-429101 HMIT co-transports myo-inositol with a proton TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-429157 https://reactome.org/PathwayBrowser/#/R-HSA-429157 ABCC4 accumulation of dense granule contents TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-429698 https://reactome.org/PathwayBrowser/#/R-HSA-429698 PRKD1,2,3 phosphorylates CERT1-2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-429714 https://reactome.org/PathwayBrowser/#/R-HSA-429714 CSNK1G2 phosphorylates p-CERT1-2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-433698 https://reactome.org/PathwayBrowser/#/R-HSA-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-434650 https://reactome.org/PathwayBrowser/#/R-HSA-434650 MATEs mediate extrusion of xenobiotics TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-435171 https://reactome.org/PathwayBrowser/#/R-HSA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-435349 https://reactome.org/PathwayBrowser/#/R-HSA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-435349 https://reactome.org/PathwayBrowser/#/R-HSA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-444393 https://reactome.org/PathwayBrowser/#/R-HSA-444393 RhCG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-444393 https://reactome.org/PathwayBrowser/#/R-HSA-444393 RhCG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-444419 https://reactome.org/PathwayBrowser/#/R-HSA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-444419 https://reactome.org/PathwayBrowser/#/R-HSA-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-444731 https://reactome.org/PathwayBrowser/#/R-HSA-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-446195 https://reactome.org/PathwayBrowser/#/R-HSA-446195 DOLK phosphorylates DCHOL to DOLP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-446200 https://reactome.org/PathwayBrowser/#/R-HSA-446200 DOLPP1 dephosphorylates DOLDP to DOLP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-446221 https://reactome.org/PathwayBrowser/#/R-HSA-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-446277 https://reactome.org/PathwayBrowser/#/R-HSA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-446277 https://reactome.org/PathwayBrowser/#/R-HSA-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-446278 https://reactome.org/PathwayBrowser/#/R-HSA-446278 RhBG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-446278 https://reactome.org/PathwayBrowser/#/R-HSA-446278 RhBG mediates ammonium influx into kidney collecting duct cells TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-450971 https://reactome.org/PathwayBrowser/#/R-HSA-450971 NNT dimer transfers proton from NADPH to NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-453337 https://reactome.org/PathwayBrowser/#/R-HSA-453337 glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-469659 https://reactome.org/PathwayBrowser/#/R-HSA-469659 SRD5A1 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-504054 https://reactome.org/PathwayBrowser/#/R-HSA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-508040 https://reactome.org/PathwayBrowser/#/R-HSA-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-508308 https://reactome.org/PathwayBrowser/#/R-HSA-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-508369 https://reactome.org/PathwayBrowser/#/R-HSA-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-508473 https://reactome.org/PathwayBrowser/#/R-HSA-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-514604 https://reactome.org/PathwayBrowser/#/R-HSA-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-5210943 https://reactome.org/PathwayBrowser/#/R-HSA-5210943 pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-5210947 https://reactome.org/PathwayBrowser/#/R-HSA-5210947 pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-HSA-5228406 https://reactome.org/PathwayBrowser/#/R-HSA-5228406 tetX HC transports tetX LC from target cell endosome membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5244404 https://reactome.org/PathwayBrowser/#/R-HSA-5244404 botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5244428 https://reactome.org/PathwayBrowser/#/R-HSA-5244428 botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5244506 https://reactome.org/PathwayBrowser/#/R-HSA-5244506 botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5246514 https://reactome.org/PathwayBrowser/#/R-HSA-5246514 botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5250616 https://reactome.org/PathwayBrowser/#/R-HSA-5250616 botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5250884 https://reactome.org/PathwayBrowser/#/R-HSA-5250884 botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-5244410 H+ [synaptic vesicle lumen] R-HSA-5250972 https://reactome.org/PathwayBrowser/#/R-HSA-5250972 botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5263614 https://reactome.org/PathwayBrowser/#/R-HSA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5263616 https://reactome.org/PathwayBrowser/#/R-HSA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 TAS Homo sapiens 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-HSA-5336420 https://reactome.org/PathwayBrowser/#/R-HSA-5336420 DT fragment B transports DT fragment A from target cell endosome membrane TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5340130 https://reactome.org/PathwayBrowser/#/R-HSA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-5340130 https://reactome.org/PathwayBrowser/#/R-HSA-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5362518 https://reactome.org/PathwayBrowser/#/R-HSA-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5362522 https://reactome.org/PathwayBrowser/#/R-HSA-5362522 ALDHs oxidise atRAL to atRA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5362564 https://reactome.org/PathwayBrowser/#/R-HSA-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5362721 https://reactome.org/PathwayBrowser/#/R-HSA-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5419165 https://reactome.org/PathwayBrowser/#/R-HSA-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5423637 https://reactome.org/PathwayBrowser/#/R-HSA-5423637 AKR dimers reduce AFBDHO to AFBDOH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5433066 https://reactome.org/PathwayBrowser/#/R-HSA-5433066 Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548800 https://reactome.org/PathwayBrowser/#/R-HSA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548814 https://reactome.org/PathwayBrowser/#/R-HSA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548815 https://reactome.org/PathwayBrowser/#/R-HSA-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548818 https://reactome.org/PathwayBrowser/#/R-HSA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548830 https://reactome.org/PathwayBrowser/#/R-HSA-548830 ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-548831 https://reactome.org/PathwayBrowser/#/R-HSA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5615668 https://reactome.org/PathwayBrowser/#/R-HSA-5615668 AKR1C3 reduces atRAL to atROL TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5623558 https://reactome.org/PathwayBrowser/#/R-HSA-5623558 Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-5623643 https://reactome.org/PathwayBrowser/#/R-HSA-5623643 RDH13 reduces atRAL to atROL TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5624211 https://reactome.org/PathwayBrowser/#/R-HSA-5624211 Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-5624239 https://reactome.org/PathwayBrowser/#/R-HSA-5624239 Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol TAS Homo sapiens 15378 R-ALL-428548 H+ [synaptic vesicle] R-HSA-5624256 https://reactome.org/PathwayBrowser/#/R-HSA-5624256 Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5625015 https://reactome.org/PathwayBrowser/#/R-HSA-5625015 Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5625029 https://reactome.org/PathwayBrowser/#/R-HSA-5625029 SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5625574 https://reactome.org/PathwayBrowser/#/R-HSA-5625574 Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5652172 https://reactome.org/PathwayBrowser/#/R-HSA-5652172 AKR1B1 reduces Glc to D-sorbitol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5652195 https://reactome.org/PathwayBrowser/#/R-HSA-5652195 SORD oxidizes D-sorbitol to Fru TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5653850 https://reactome.org/PathwayBrowser/#/R-HSA-5653850 Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5655955 https://reactome.org/PathwayBrowser/#/R-HSA-5655955 OLAH hydrolyzes decanoyl-FASN dimer to DECA and FASN dimer IEA Homo sapiens 15378 R-ALL-425978 H+ [early endosome lumen] R-HSA-5661039 https://reactome.org/PathwayBrowser/#/R-HSA-5661039 Defective SLC9A6 does not exchange Na+ for H+ across the early endosome membrane TAS Homo sapiens 15378 R-ALL-425999 H+ [late endosome lumen] R-HSA-5661086 https://reactome.org/PathwayBrowser/#/R-HSA-5661086 Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5661240 https://reactome.org/PathwayBrowser/#/R-HSA-5661240 DCXR tetramer reduces L-xylulose to xylitol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5661256 https://reactome.org/PathwayBrowser/#/R-HSA-5661256 AKR1A1 reduces D-glucuronate to L-gulonate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5661290 https://reactome.org/PathwayBrowser/#/R-HSA-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5662471 https://reactome.org/PathwayBrowser/#/R-HSA-5662471 SORD tetramer oxidizes xylitol to D-xylulose TAS Homo sapiens 15378 R-ALL-5668577 H+ [melanosome lumen] R-HSA-5662662 https://reactome.org/PathwayBrowser/#/R-HSA-5662662 Tyrosinase oxidises tyrosine to dopaquinone TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5662851 https://reactome.org/PathwayBrowser/#/R-HSA-5662851 Defective DCXR does not reduce L-xylulose to xylitol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-5690042 https://reactome.org/PathwayBrowser/#/R-HSA-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-5690046 https://reactome.org/PathwayBrowser/#/R-HSA-5690046 PPT2 hydrolyses PALMCoA to PALM TAS Homo sapiens 15378 R-ALL-428040 H+ [lysosomal lumen] R-HSA-5690517 https://reactome.org/PathwayBrowser/#/R-HSA-5690517 PPT1 hydrolyses palmitoylated proteins TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5692237 https://reactome.org/PathwayBrowser/#/R-HSA-5692237 ADH5 oxidises S-HMGSH to S-FGSH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5692261 https://reactome.org/PathwayBrowser/#/R-HSA-5692261 ALDH3A2-1 oxidises HD2NAL to PALM TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5692283 https://reactome.org/PathwayBrowser/#/R-HSA-5692283 ALD3A1 oxidises 4HPCP to CXPA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5693148 https://reactome.org/PathwayBrowser/#/R-HSA-5693148 BCKDK phosphorylates BCKDH TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-5693347 https://reactome.org/PathwayBrowser/#/R-HSA-5693347 CRYM reduces P2C to PPCA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5693390 https://reactome.org/PathwayBrowser/#/R-HSA-5693390 HSD17B11 dehydrogenates EST17b to E1 TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-5693691 https://reactome.org/PathwayBrowser/#/R-HSA-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5693967 https://reactome.org/PathwayBrowser/#/R-HSA-5693967 PXLP-K754-GLDC dimer decarboxylates Gly TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5694018 https://reactome.org/PathwayBrowser/#/R-HSA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5694462 https://reactome.org/PathwayBrowser/#/R-HSA-5694462 ABHD6,12 hydrolyse 3AG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5696021 https://reactome.org/PathwayBrowser/#/R-HSA-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5696080 https://reactome.org/PathwayBrowser/#/R-HSA-5696080 ALDH3B1 oxidises HXAL to PALM TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5696091 https://reactome.org/PathwayBrowser/#/R-HSA-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5696101 https://reactome.org/PathwayBrowser/#/R-HSA-5696101 ALDH8A1 oxidises 9cRAL to 9cRA TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5696457 https://reactome.org/PathwayBrowser/#/R-HSA-5696457 BDH2 dehydrogenates 3HBA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-5696822 https://reactome.org/PathwayBrowser/#/R-HSA-5696822 AKR1B15 reduces EST17b to E1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-5696838 https://reactome.org/PathwayBrowser/#/R-HSA-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-597628 https://reactome.org/PathwayBrowser/#/R-HSA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6783221 https://reactome.org/PathwayBrowser/#/R-HSA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6783883 https://reactome.org/PathwayBrowser/#/R-HSA-6783883 P6C transforms to 2AMAS TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6783939 https://reactome.org/PathwayBrowser/#/R-HSA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6783955 https://reactome.org/PathwayBrowser/#/R-HSA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6784224 https://reactome.org/PathwayBrowser/#/R-HSA-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6784402 https://reactome.org/PathwayBrowser/#/R-HSA-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-6785933 https://reactome.org/PathwayBrowser/#/R-HSA-6785933 UGT8 transfers Gal from UDP-Gal to CERA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6786245 https://reactome.org/PathwayBrowser/#/R-HSA-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6786257 https://reactome.org/PathwayBrowser/#/R-HSA-6786257 DCTPP1 hydrolyses 5idCTP IEA Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6786720 https://reactome.org/PathwayBrowser/#/R-HSA-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6787642 https://reactome.org/PathwayBrowser/#/R-HSA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6787757 https://reactome.org/PathwayBrowser/#/R-HSA-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6788611 https://reactome.org/PathwayBrowser/#/R-HSA-6788611 HYKK phosphorylates 5HLYS TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6788974 https://reactome.org/PathwayBrowser/#/R-HSA-6788974 Hypochlorous acid and nitrite react to nitryl chloride (NO2Cl) TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6788975 https://reactome.org/PathwayBrowser/#/R-HSA-6788975 Superoxide anion dismutates to H2O2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6788999 https://reactome.org/PathwayBrowser/#/R-HSA-6788999 HV1-mediated H+ transfer TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6788999 https://reactome.org/PathwayBrowser/#/R-HSA-6788999 HV1-mediated H+ transfer TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6789031 https://reactome.org/PathwayBrowser/#/R-HSA-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 15378 R-ALL-1132304 H+ [cytoplasm] R-HSA-6789109 https://reactome.org/PathwayBrowser/#/R-HSA-6789109 Superoxide anion reacts with Fe-S cluster TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6789126 https://reactome.org/PathwayBrowser/#/R-HSA-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6793590 https://reactome.org/PathwayBrowser/#/R-HSA-6793590 LIPT2 transfers octanoyl group to GCSH TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6793591 https://reactome.org/PathwayBrowser/#/R-HSA-6793591 LIAS synthesizes lipoyl-GCSH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6798317 https://reactome.org/PathwayBrowser/#/R-HSA-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6798335 https://reactome.org/PathwayBrowser/#/R-HSA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6799495 https://reactome.org/PathwayBrowser/#/R-HSA-6799495 GLYCTK phosphorylates DGA to 3PDGA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6799722 https://reactome.org/PathwayBrowser/#/R-HSA-6799722 TP53I3 oxidoreductase generates unstable semiquinones TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6801342 https://reactome.org/PathwayBrowser/#/R-HSA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6803771 https://reactome.org/PathwayBrowser/#/R-HSA-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-6803998 https://reactome.org/PathwayBrowser/#/R-HSA-6803998 Nitrite ion and HNO2 form a conjugated acid-base pair TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-6806647 https://reactome.org/PathwayBrowser/#/R-HSA-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6806831 https://reactome.org/PathwayBrowser/#/R-HSA-6806831 CYB5Rs reduce MetHb to HbA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6806967 https://reactome.org/PathwayBrowser/#/R-HSA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6807055 https://reactome.org/PathwayBrowser/#/R-HSA-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6807064 https://reactome.org/PathwayBrowser/#/R-HSA-6807064 DHCR24 reduces ZYMOL to ZYMSTNL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6807826 https://reactome.org/PathwayBrowser/#/R-HSA-6807826 LDHAL6B reduces PYR to LACT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6808464 https://reactome.org/PathwayBrowser/#/R-HSA-6808464 ALDH3B2 oxidises HXAL to PALM TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-6808487 https://reactome.org/PathwayBrowser/#/R-HSA-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6808496 https://reactome.org/PathwayBrowser/#/R-HSA-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6809264 https://reactome.org/PathwayBrowser/#/R-HSA-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6809287 https://reactome.org/PathwayBrowser/#/R-HSA-6809287 NUDT12 hydrolyses NADH to NMNH TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6809354 https://reactome.org/PathwayBrowser/#/R-HSA-6809354 NUDT7 hydrolyses CoA-SH to 3',5'-ADP and PPANT IEA Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6809810 https://reactome.org/PathwayBrowser/#/R-HSA-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-6810474 https://reactome.org/PathwayBrowser/#/R-HSA-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6810594 https://reactome.org/PathwayBrowser/#/R-HSA-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6813749 https://reactome.org/PathwayBrowser/#/R-HSA-6813749 ALDH1A1 oxidises GA to DGA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-6814165 https://reactome.org/PathwayBrowser/#/R-HSA-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70286 https://reactome.org/PathwayBrowser/#/R-HSA-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70333 https://reactome.org/PathwayBrowser/#/R-HSA-70333 KHK dimer phosphorylates Fru to Fru 1-P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70355 https://reactome.org/PathwayBrowser/#/R-HSA-70355 GALK1 phosphorylates Gal to Gal1P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70377 https://reactome.org/PathwayBrowser/#/R-HSA-70377 G6PD multimers dehydrogenate G6P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70420 https://reactome.org/PathwayBrowser/#/R-HSA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70449 https://reactome.org/PathwayBrowser/#/R-HSA-70449 GADPH tetramer dehydrogenates GA3P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70467 https://reactome.org/PathwayBrowser/#/R-HSA-70467 PFK tetramer phosphorylates Fru(6)P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70482 https://reactome.org/PathwayBrowser/#/R-HSA-70482 GAPDH tetramers reduce 1,3BPG to GA3P TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70501 https://reactome.org/PathwayBrowser/#/R-HSA-70501 PC carboxylates PYR to OA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70510 https://reactome.org/PathwayBrowser/#/R-HSA-70510 LDH tetramer oxidises LACT to PYR TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70589 https://reactome.org/PathwayBrowser/#/R-HSA-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70599 https://reactome.org/PathwayBrowser/#/R-HSA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70600 https://reactome.org/PathwayBrowser/#/R-HSA-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-70606 https://reactome.org/PathwayBrowser/#/R-HSA-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70655 https://reactome.org/PathwayBrowser/#/R-HSA-70655 L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70664 https://reactome.org/PathwayBrowser/#/R-HSA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70670 https://reactome.org/PathwayBrowser/#/R-HSA-70670 PRODH oxidises L-Pro to 1PYR-5COOH TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70679 https://reactome.org/PathwayBrowser/#/R-HSA-70679 ALDH4A1 oxidises L-GluSS to Glu TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70745 https://reactome.org/PathwayBrowser/#/R-HSA-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70773 https://reactome.org/PathwayBrowser/#/R-HSA-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70800 https://reactome.org/PathwayBrowser/#/R-HSA-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70837 https://reactome.org/PathwayBrowser/#/R-HSA-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70859 https://reactome.org/PathwayBrowser/#/R-HSA-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70881 https://reactome.org/PathwayBrowser/#/R-HSA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70885 https://reactome.org/PathwayBrowser/#/R-HSA-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70893 https://reactome.org/PathwayBrowser/#/R-HSA-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70938 https://reactome.org/PathwayBrowser/#/R-HSA-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70940 https://reactome.org/PathwayBrowser/#/R-HSA-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70941 https://reactome.org/PathwayBrowser/#/R-HSA-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70975 https://reactome.org/PathwayBrowser/#/R-HSA-70975 CS acetylates OA to citrate TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-70979 https://reactome.org/PathwayBrowser/#/R-HSA-70979 MDH2 dimer dehydrogenates MAL TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-71046 https://reactome.org/PathwayBrowser/#/R-HSA-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71130 https://reactome.org/PathwayBrowser/#/R-HSA-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71181 https://reactome.org/PathwayBrowser/#/R-HSA-71181 FAH cleaves 4FAA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71189 https://reactome.org/PathwayBrowser/#/R-HSA-71189 AFMID hydrolyses NFK to L-KYN IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71217 https://reactome.org/PathwayBrowser/#/R-HSA-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71223 https://reactome.org/PathwayBrowser/#/R-HSA-71223 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71239 https://reactome.org/PathwayBrowser/#/R-HSA-71239 2-aminomuconate semialdehyde + NAD+ + H2O => aminomuconate + NADH + H+ IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71260 https://reactome.org/PathwayBrowser/#/R-HSA-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71286 https://reactome.org/PathwayBrowser/#/R-HSA-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71296 https://reactome.org/PathwayBrowser/#/R-HSA-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-71401 https://reactome.org/PathwayBrowser/#/R-HSA-71401 OGDH dimer decarboxylates 2-OG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71541 https://reactome.org/PathwayBrowser/#/R-HSA-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71588 https://reactome.org/PathwayBrowser/#/R-HSA-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71670 https://reactome.org/PathwayBrowser/#/R-HSA-71670 PKM dephosphorylates PEP to PYR TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71682 https://reactome.org/PathwayBrowser/#/R-HSA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71691 https://reactome.org/PathwayBrowser/#/R-HSA-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71707 https://reactome.org/PathwayBrowser/#/R-HSA-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-71723 https://reactome.org/PathwayBrowser/#/R-HSA-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71802 https://reactome.org/PathwayBrowser/#/R-HSA-71802 PFKFKB dimer phosphorylates Fru(6)P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-71849 https://reactome.org/PathwayBrowser/#/R-HSA-71849 LDH tetramer reduces PYR to LACT TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73564 https://reactome.org/PathwayBrowser/#/R-HSA-73564 UMPS dimer decarboxylates OMP to UMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73571 https://reactome.org/PathwayBrowser/#/R-HSA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73573 https://reactome.org/PathwayBrowser/#/R-HSA-73573 CAD hexamer transforms CAP to N-carb-L-Asp TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73577 https://reactome.org/PathwayBrowser/#/R-HSA-73577 CAD hexamer transforms L-Gln to CAP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73580 https://reactome.org/PathwayBrowser/#/R-HSA-73580 PRPS dimers pyrophosphorylate R5P using ATP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73585 https://reactome.org/PathwayBrowser/#/R-HSA-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73589 https://reactome.org/PathwayBrowser/#/R-HSA-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73591 https://reactome.org/PathwayBrowser/#/R-HSA-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73596 https://reactome.org/PathwayBrowser/#/R-HSA-73596 dCMP + H2O => dUMP + NH4+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73616 https://reactome.org/PathwayBrowser/#/R-HSA-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73618 https://reactome.org/PathwayBrowser/#/R-HSA-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73620 https://reactome.org/PathwayBrowser/#/R-HSA-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73646 https://reactome.org/PathwayBrowser/#/R-HSA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73647 https://reactome.org/PathwayBrowser/#/R-HSA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-73666 https://reactome.org/PathwayBrowser/#/R-HSA-73666 dUTP + H2O => dUMP + pyrophosphate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73792 https://reactome.org/PathwayBrowser/#/R-HSA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73794 https://reactome.org/PathwayBrowser/#/R-HSA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73805 https://reactome.org/PathwayBrowser/#/R-HSA-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73806 https://reactome.org/PathwayBrowser/#/R-HSA-73806 AIR + CO2 => CAIR TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73810 https://reactome.org/PathwayBrowser/#/R-HSA-73810 FGAM + ATP => AIR + ADP + Pi TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73812 https://reactome.org/PathwayBrowser/#/R-HSA-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73813 https://reactome.org/PathwayBrowser/#/R-HSA-73813 GAR + 10-Formyl-THF => FGAR + THF TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-73814 https://reactome.org/PathwayBrowser/#/R-HSA-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-73912 https://reactome.org/PathwayBrowser/#/R-HSA-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-73920 https://reactome.org/PathwayBrowser/#/R-HSA-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-74255 https://reactome.org/PathwayBrowser/#/R-HSA-74255 Guanine + H2O => Xanthine + NH4+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-74723 https://reactome.org/PathwayBrowser/#/R-HSA-74723 Endosome acidification TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-74723 https://reactome.org/PathwayBrowser/#/R-HSA-74723 Endosome acidification TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-74872 https://reactome.org/PathwayBrowser/#/R-HSA-74872 RDH10,11 oxidise 11cROL to 11cRAL TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-749448 https://reactome.org/PathwayBrowser/#/R-HSA-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-749452 https://reactome.org/PathwayBrowser/#/R-HSA-749452 The Ligand:GPCR:Gq complex dissociates TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-75851 https://reactome.org/PathwayBrowser/#/R-HSA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-75872 https://reactome.org/PathwayBrowser/#/R-HSA-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-75883 https://reactome.org/PathwayBrowser/#/R-HSA-75883 DHRS7B reduces GO3P to HXDG3P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-75889 https://reactome.org/PathwayBrowser/#/R-HSA-75889 DHAP is converted to G3P by GPD1/GPD1L TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77254 https://reactome.org/PathwayBrowser/#/R-HSA-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77283 https://reactome.org/PathwayBrowser/#/R-HSA-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77303 https://reactome.org/PathwayBrowser/#/R-HSA-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77312 https://reactome.org/PathwayBrowser/#/R-HSA-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77323 https://reactome.org/PathwayBrowser/#/R-HSA-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77331 https://reactome.org/PathwayBrowser/#/R-HSA-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-77342 https://reactome.org/PathwayBrowser/#/R-HSA-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-804969 https://reactome.org/PathwayBrowser/#/R-HSA-804969 HSD17B1 hydrogenates E1 to EST17b TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-880053 https://reactome.org/PathwayBrowser/#/R-HSA-880053 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8849638 https://reactome.org/PathwayBrowser/#/R-HSA-8849638 Dissociation of the SPINK5:KLK5 complex at low pH TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8850846 https://reactome.org/PathwayBrowser/#/R-HSA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8850854 https://reactome.org/PathwayBrowser/#/R-HSA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851089 https://reactome.org/PathwayBrowser/#/R-HSA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851110 https://reactome.org/PathwayBrowser/#/R-HSA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851129 https://reactome.org/PathwayBrowser/#/R-HSA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-8851225 https://reactome.org/PathwayBrowser/#/R-HSA-8851225 NTPDase4 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-8851234 https://reactome.org/PathwayBrowser/#/R-HSA-8851234 NTPDase4 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851356 https://reactome.org/PathwayBrowser/#/R-HSA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851396 https://reactome.org/PathwayBrowser/#/R-HSA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-HSA-8851494 https://reactome.org/PathwayBrowser/#/R-HSA-8851494 NTPDase7 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851538 https://reactome.org/PathwayBrowser/#/R-HSA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8851550 https://reactome.org/PathwayBrowser/#/R-HSA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-8856223 https://reactome.org/PathwayBrowser/#/R-HSA-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8862137 https://reactome.org/PathwayBrowser/#/R-HSA-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8862152 https://reactome.org/PathwayBrowser/#/R-HSA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8863494 https://reactome.org/PathwayBrowser/#/R-HSA-8863494 ASICs bind STOML3, (STOM) TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-8863761 https://reactome.org/PathwayBrowser/#/R-HSA-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-8866601 https://reactome.org/PathwayBrowser/#/R-HSA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8869606 https://reactome.org/PathwayBrowser/#/R-HSA-8869606 NMRK1 phosphorylates NAR to yield NAMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8869607 https://reactome.org/PathwayBrowser/#/R-HSA-8869607 NMRK2 phosphorylates NAR to yield NAMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8869627 https://reactome.org/PathwayBrowser/#/R-HSA-8869627 NMRK2 phosphorylates NR to yield NMN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8869633 https://reactome.org/PathwayBrowser/#/R-HSA-8869633 NMRK1 phosphorylates NR to yield NMN TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8870346 https://reactome.org/PathwayBrowser/#/R-HSA-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8875623 https://reactome.org/PathwayBrowser/#/R-HSA-8875623 SLC25A18,22 import L-Glu, H+ TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8875623 https://reactome.org/PathwayBrowser/#/R-HSA-8875623 SLC25A18,22 import L-Glu, H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8876789 https://reactome.org/PathwayBrowser/#/R-HSA-8876789 CARNMT1 methylates CARN to Anserine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8876889 https://reactome.org/PathwayBrowser/#/R-HSA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-8878914 https://reactome.org/PathwayBrowser/#/R-HSA-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-888548 https://reactome.org/PathwayBrowser/#/R-HSA-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-888572 https://reactome.org/PathwayBrowser/#/R-HSA-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-888577 https://reactome.org/PathwayBrowser/#/R-HSA-888577 Synthesis of GABA by GAD2 TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-8933635 https://reactome.org/PathwayBrowser/#/R-HSA-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8936442 https://reactome.org/PathwayBrowser/#/R-HSA-8936442 MARC1,MARC2 reduce N-hydroxylated compounds TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8938076 https://reactome.org/PathwayBrowser/#/R-HSA-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8939959 https://reactome.org/PathwayBrowser/#/R-HSA-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8940070 https://reactome.org/PathwayBrowser/#/R-HSA-8940070 NT5E:Zn2+ hydrolyses NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8942575 https://reactome.org/PathwayBrowser/#/R-HSA-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8949687 https://reactome.org/PathwayBrowser/#/R-HSA-8949687 LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-8949687 https://reactome.org/PathwayBrowser/#/R-HSA-8949687 LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) IEA Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8952873 https://reactome.org/PathwayBrowser/#/R-HSA-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8954468 https://reactome.org/PathwayBrowser/#/R-HSA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-8955030 https://reactome.org/PathwayBrowser/#/R-HSA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8955760 https://reactome.org/PathwayBrowser/#/R-HSA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8955844 https://reactome.org/PathwayBrowser/#/R-HSA-8955844 RBKS phosphorylates ribose to R5P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8956427 https://reactome.org/PathwayBrowser/#/R-HSA-8956427 RETSAT reduces atROL to at-13,14-dhROL IEA Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8959510 https://reactome.org/PathwayBrowser/#/R-HSA-8959510 SEPHS2 phosphorylates H2Se to form SELP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-8959719 https://reactome.org/PathwayBrowser/#/R-HSA-8959719 SHPK phosphorylates Sedo to Sedo7P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9009950 https://reactome.org/PathwayBrowser/#/R-HSA-9009950 PDE12 cleaves 2'-5' oligoadenylates TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9011595 https://reactome.org/PathwayBrowser/#/R-HSA-9011595 GSTZ1 dimer dehalogenates DCA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9012016 https://reactome.org/PathwayBrowser/#/R-HSA-9012016 FAHD1 dimer hydrolyses OA to PYR TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9012036 https://reactome.org/PathwayBrowser/#/R-HSA-9012036 ME1 tetramer decarboxylates MAL to PYR TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-9013198 https://reactome.org/PathwayBrowser/#/R-HSA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9024766 https://reactome.org/PathwayBrowser/#/R-HSA-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027625 https://reactome.org/PathwayBrowser/#/R-HSA-9027625 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027631 https://reactome.org/PathwayBrowser/#/R-HSA-9027631 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9027632 https://reactome.org/PathwayBrowser/#/R-HSA-9027632 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-917811 https://reactome.org/PathwayBrowser/#/R-HSA-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 15378 R-ALL-74722 H+ [endosome lumen] R-HSA-917841 https://reactome.org/PathwayBrowser/#/R-HSA-917841 Acidification of Tf:TfR1 containing endosome TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-917979 https://reactome.org/PathwayBrowser/#/R-HSA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-937311 https://reactome.org/PathwayBrowser/#/R-HSA-937311 ATP12A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-947541 https://reactome.org/PathwayBrowser/#/R-HSA-947541 Sulfhydrylation and ring cleavage of precursor Z TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9615042 https://reactome.org/PathwayBrowser/#/R-HSA-9615042 Viral 2',5'-PDE cleaves 2'-5' oligoadenylates TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9619024 https://reactome.org/PathwayBrowser/#/R-HSA-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9620103 https://reactome.org/PathwayBrowser/#/R-HSA-9620103 ALDH2 transforms GTN to NO TAS Homo sapiens 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-HSA-9625540 https://reactome.org/PathwayBrowser/#/R-HSA-9625540 Cys-sulfenyl chloride is converted to Cys-sulfenic acid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9636560 https://reactome.org/PathwayBrowser/#/R-HSA-9636560 Eis acetylates DUSP16 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9637699 https://reactome.org/PathwayBrowser/#/R-HSA-9637699 CpnT hydrolyses NAD+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9640302 https://reactome.org/PathwayBrowser/#/R-HSA-9640302 Asc.- radical dissociates to AscH- and DeHA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9640321 https://reactome.org/PathwayBrowser/#/R-HSA-9640321 2,3-DKG hydrolyses to ERU and oxalate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9645220 https://reactome.org/PathwayBrowser/#/R-HSA-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9650165 https://reactome.org/PathwayBrowser/#/R-HSA-9650165 ASIC trimers bind H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9668415 https://reactome.org/PathwayBrowser/#/R-HSA-9668415 VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-HSA-9683467 https://reactome.org/PathwayBrowser/#/R-HSA-9683467 CQ, HCQ are protonated to CQ2+, HCQ2+ TAS Homo sapiens 15378 R-ALL-9683057 H+ [endoplasmic reticulum-Golgi intermediate compartment] R-HSA-9683648 https://reactome.org/PathwayBrowser/#/R-HSA-9683648 Spike trimer glycoside chains are extended TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9683664 https://reactome.org/PathwayBrowser/#/R-HSA-9683664 GSK3 phosphorylates Nucleoprotein TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9683669 https://reactome.org/PathwayBrowser/#/R-HSA-9683669 E protein gets N-glycosylated TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9683751 https://reactome.org/PathwayBrowser/#/R-HSA-9683751 M protein gets N-glycosylated TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9683755 https://reactome.org/PathwayBrowser/#/R-HSA-9683755 Spike protein gets N-glycosylated TAS Homo sapiens 15378 R-ALL-9683057 H+ [endoplasmic reticulum-Golgi intermediate compartment] R-HSA-9683760 https://reactome.org/PathwayBrowser/#/R-HSA-9683760 GalNAc is transferred onto 3a TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9684261 https://reactome.org/PathwayBrowser/#/R-HSA-9684261 nsp4 is glycosylated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9684275 https://reactome.org/PathwayBrowser/#/R-HSA-9684275 nsp3-4 is glycosylated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9684290 https://reactome.org/PathwayBrowser/#/R-HSA-9684290 nsp3 is glycosylated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9686061 https://reactome.org/PathwayBrowser/#/R-HSA-9686061 Nucleoprotein is ADP-ribosylated TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9694331 https://reactome.org/PathwayBrowser/#/R-HSA-9694331 nsp3-4 is glycosylated IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9694389 https://reactome.org/PathwayBrowser/#/R-HSA-9694389 nsp3 is glycosylated IEA Homo sapiens 15378 R-ALL-9683057 H+ [endoplasmic reticulum-Golgi intermediate compartment] R-HSA-9694438 https://reactome.org/PathwayBrowser/#/R-HSA-9694438 GalNAc is transferred onto 3a IEA Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9694525 https://reactome.org/PathwayBrowser/#/R-HSA-9694525 M protein gets N-glycosylated IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9694611 https://reactome.org/PathwayBrowser/#/R-HSA-9694611 nsp4 is glycosylated IEA Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9694790 https://reactome.org/PathwayBrowser/#/R-HSA-9694790 E protein gets N-glycosylated IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9695949 https://reactome.org/PathwayBrowser/#/R-HSA-9695949 SPHK2 phosphorylates sphingoid TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9705713 https://reactome.org/PathwayBrowser/#/R-HSA-9705713 SRD5A2 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9705714 https://reactome.org/PathwayBrowser/#/R-HSA-9705714 SRD5A3 dehydrogenates TEST to DHTEST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9709098 https://reactome.org/PathwayBrowser/#/R-HSA-9709098 DHFR dimer reduces FOLA to DHF TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9727198 https://reactome.org/PathwayBrowser/#/R-HSA-9727198 ATP4A:ATP4B exchanges K+ for H+ TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9727347 https://reactome.org/PathwayBrowser/#/R-HSA-9727347 XDH dehydrogenates hypoxanthine to form xanthine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9727349 https://reactome.org/PathwayBrowser/#/R-HSA-9727349 XDH dehydrogenates xanthine to form urate TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729260 https://reactome.org/PathwayBrowser/#/R-HSA-9729260 GSK3 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729279 https://reactome.org/PathwayBrowser/#/R-HSA-9729279 Nucleoprotein is ADP-ribosylated IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729283 https://reactome.org/PathwayBrowser/#/R-HSA-9729283 Nucleoprotein is methylated by PRMT1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729300 https://reactome.org/PathwayBrowser/#/R-HSA-9729300 Unknown kinase phosphorylates nucleoprotein TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729318 https://reactome.org/PathwayBrowser/#/R-HSA-9729318 CSNK1A1 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729330 https://reactome.org/PathwayBrowser/#/R-HSA-9729330 SRPK1/2 phosphorylates nucleoprotein TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729542 https://reactome.org/PathwayBrowser/#/R-HSA-9729542 OTOP1 transports H+ from the extracellular region to the cytosol IEA Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9729542 https://reactome.org/PathwayBrowser/#/R-HSA-9729542 OTOP1 transports H+ from the extracellular region to the cytosol IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9729870 https://reactome.org/PathwayBrowser/#/R-HSA-9729870 KCNJ2 (KIR2.1) transports K+ from the extracellular region to the cytosol IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9731228 https://reactome.org/PathwayBrowser/#/R-HSA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9731590 https://reactome.org/PathwayBrowser/#/R-HSA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9731613 https://reactome.org/PathwayBrowser/#/R-HSA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9731632 https://reactome.org/PathwayBrowser/#/R-HSA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9731661 https://reactome.org/PathwayBrowser/#/R-HSA-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9748945 https://reactome.org/PathwayBrowser/#/R-HSA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9748957 https://reactome.org/PathwayBrowser/#/R-HSA-9748957 GMPS dimer transforms 6TXMP to 6TGMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9748979 https://reactome.org/PathwayBrowser/#/R-HSA-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9748983 https://reactome.org/PathwayBrowser/#/R-HSA-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9748991 https://reactome.org/PathwayBrowser/#/R-HSA-9748991 XDH oxidises 6MP to 6TU TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9749609 https://reactome.org/PathwayBrowser/#/R-HSA-9749609 BCHE hydrolyzes ASA- TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9749647 https://reactome.org/PathwayBrowser/#/R-HSA-9749647 CES2 hydrolyzes ASA- TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9749792 https://reactome.org/PathwayBrowser/#/R-HSA-9749792 CES1,CES2 hydrolyze ASA- to ST TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9755937 https://reactome.org/PathwayBrowser/#/R-HSA-9755937 DHCR24 reduces LAN to 24,25-dhLAN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756134 https://reactome.org/PathwayBrowser/#/R-HSA-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756136 https://reactome.org/PathwayBrowser/#/R-HSA-9756136 PON1,3 hydrolyse 2-OH-ATVL to 2-OH-ATV IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756150 https://reactome.org/PathwayBrowser/#/R-HSA-9756150 PON1,3 hydrolyse 4-OH-ATVL to 4-OH-ATV IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756156 https://reactome.org/PathwayBrowser/#/R-HSA-9756156 UGT1A3 lactonizes ATV to ATVL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756177 https://reactome.org/PathwayBrowser/#/R-HSA-9756177 PON1,3 hydrolyse ATVL to ATV TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9756183 https://reactome.org/PathwayBrowser/#/R-HSA-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-975629 https://reactome.org/PathwayBrowser/#/R-HSA-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL TAS Homo sapiens 15378 R-ALL-351626 H+ [extracellular region] R-HSA-9757434 https://reactome.org/PathwayBrowser/#/R-HSA-9757434 Acetylsalicylic acid dissolves TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9757706 https://reactome.org/PathwayBrowser/#/R-HSA-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9758661 https://reactome.org/PathwayBrowser/#/R-HSA-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9758682 https://reactome.org/PathwayBrowser/#/R-HSA-9758682 AKR1C1 hydrogenates PREDN,PREDL TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9759259 https://reactome.org/PathwayBrowser/#/R-HSA-9759259 HSD11B2 dehydrogenates PREDL to PREDN TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9759549 https://reactome.org/PathwayBrowser/#/R-HSA-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9760094 https://reactome.org/PathwayBrowser/#/R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-977301 https://reactome.org/PathwayBrowser/#/R-HSA-977301 Histidine is decarboxylated to histamine TAS Homo sapiens 15378 R-ALL-193465 H+ [peroxisomal matrix] R-HSA-977317 https://reactome.org/PathwayBrowser/#/R-HSA-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-977348 https://reactome.org/PathwayBrowser/#/R-HSA-977348 PHGDH tetramer dehydrogenates 3PG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9773976 https://reactome.org/PathwayBrowser/#/R-HSA-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9793628 https://reactome.org/PathwayBrowser/#/R-HSA-9793628 Cipro is imported by organic cation transporters TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9794270 https://reactome.org/PathwayBrowser/#/R-HSA-9794270 SLCO1A2 transports Cipro(1+) into the cytosol TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9815529 https://reactome.org/PathwayBrowser/#/R-HSA-9815529 nsp12 transfers guanylyl onto SARS-CoV-2 plus strand subgenomic RNAs TAS Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-9817513 https://reactome.org/PathwayBrowser/#/R-HSA-9817513 AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine IEA Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-9822583 https://reactome.org/PathwayBrowser/#/R-HSA-9822583 METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) IEA Homo sapiens 15378 R-ALL-9668967 H+ [nucleoplasm] R-HSA-9825790 https://reactome.org/PathwayBrowser/#/R-HSA-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9837337 https://reactome.org/PathwayBrowser/#/R-HSA-9837337 DCAKD phosphorylates DP-CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9837354 https://reactome.org/PathwayBrowser/#/R-HSA-9837354 NUDT8 hydrolyzes CoA-SH to PPANT IEA Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9843721 https://reactome.org/PathwayBrowser/#/R-HSA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9844587 https://reactome.org/PathwayBrowser/#/R-HSA-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9844860 https://reactome.org/PathwayBrowser/#/R-HSA-9844860 ST3GAL5 transfers NeuNAc to ceramides TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9845516 https://reactome.org/PathwayBrowser/#/R-HSA-9845516 B3GALT4 transfers Gal to gangliosides TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9845538 https://reactome.org/PathwayBrowser/#/R-HSA-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9845587 https://reactome.org/PathwayBrowser/#/R-HSA-9845587 ST8SIA5 transfers Neu5Ac to gangliosides TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9846305 https://reactome.org/PathwayBrowser/#/R-HSA-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9846332 https://reactome.org/PathwayBrowser/#/R-HSA-9846332 FUT1,2 transfer fucose to gangliosides TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9846477 https://reactome.org/PathwayBrowser/#/R-HSA-9846477 A4GALT transfers galactose to LacCer TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9846501 https://reactome.org/PathwayBrowser/#/R-HSA-9846501 B3GNT5 transfers GlcNAc to LacCer TAS Homo sapiens 15378 R-ALL-425969 H+ [Golgi lumen] R-HSA-9851347 https://reactome.org/PathwayBrowser/#/R-HSA-9851347 B4GALT5/6 transfer Gal to GlcCer TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9853499 https://reactome.org/PathwayBrowser/#/R-HSA-9853499 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9854315 https://reactome.org/PathwayBrowser/#/R-HSA-9854315 CSKMT methylates Citrate Synthase TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9854415 https://reactome.org/PathwayBrowser/#/R-HSA-9854415 ACAT1 tetramer acetylates IDH2 dimer TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9856794 https://reactome.org/PathwayBrowser/#/R-HSA-9856794 Unknown dehydrogenase oxidizes 4-HBz TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9856871 https://reactome.org/PathwayBrowser/#/R-HSA-9856871 MDH1 reduces OA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9858321 https://reactome.org/PathwayBrowser/#/R-HSA-9858321 DHTKD1 dimer decarboxylates 2-OA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9858589 https://reactome.org/PathwayBrowser/#/R-HSA-9858589 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9858590 https://reactome.org/PathwayBrowser/#/R-HSA-9858590 DLST transfers glutaryl to CoA TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9859148 https://reactome.org/PathwayBrowser/#/R-HSA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9859172 https://reactome.org/PathwayBrowser/#/R-HSA-9859172 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9861616 https://reactome.org/PathwayBrowser/#/R-HSA-9861616 DLD dimer dehydrogenates dihydrolipoyl TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9861642 https://reactome.org/PathwayBrowser/#/R-HSA-9861642 NEK1 phosphorylates ME1 TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9861660 https://reactome.org/PathwayBrowser/#/R-HSA-9861660 ME1 tetramer decarboxylates OA to PYR TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9861734 https://reactome.org/PathwayBrowser/#/R-HSA-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9863531 https://reactome.org/PathwayBrowser/#/R-HSA-9863531 GS-MCA spontaneously hydrolyzes TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9864415 https://reactome.org/PathwayBrowser/#/R-HSA-9864415 AAC1 imports a proton TAS Homo sapiens 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-HSA-9864415 https://reactome.org/PathwayBrowser/#/R-HSA-9864415 AAC1 imports a proton TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9865121 https://reactome.org/PathwayBrowser/#/R-HSA-9865121 BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9909159 https://reactome.org/PathwayBrowser/#/R-HSA-9909159 HK1 phosphorylates Mannose to Man6P TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9915971 https://reactome.org/PathwayBrowser/#/R-HSA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9915993 https://reactome.org/PathwayBrowser/#/R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9915997 https://reactome.org/PathwayBrowser/#/R-HSA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-HSA-9929439 https://reactome.org/PathwayBrowser/#/R-HSA-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9931850 https://reactome.org/PathwayBrowser/#/R-HSA-9931850 AKR1B1 reduces galactose to galactitol IEA Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9935449 https://reactome.org/PathwayBrowser/#/R-HSA-9935449 FUT10 O-fucosylates EMI domain-containing proteins TAS Homo sapiens 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-HSA-9935469 https://reactome.org/PathwayBrowser/#/R-HSA-9935469 FUT11 O-fucosylates EMI domain-containing proteins TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9937295 https://reactome.org/PathwayBrowser/#/R-HSA-9937295 SRD5A3 reduces polyprenal to dolichal TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9937298 https://reactome.org/PathwayBrowser/#/R-HSA-9937298 DHRSX oxidizes polyprenol to polyprenal TAS Homo sapiens 15378 R-ALL-70106 H+ [cytosol] R-HSA-9937340 https://reactome.org/PathwayBrowser/#/R-HSA-9937340 DHRSX reduces dolichal to dolichol TAS Homo sapiens 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-109343 https://reactome.org/PathwayBrowser/#/R-MMU-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-111215 https://reactome.org/PathwayBrowser/#/R-MMU-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-111524 https://reactome.org/PathwayBrowser/#/R-MMU-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-111883 https://reactome.org/PathwayBrowser/#/R-MMU-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1222516 https://reactome.org/PathwayBrowser/#/R-MMU-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-1222516 https://reactome.org/PathwayBrowser/#/R-MMU-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Mus musculus 15378 R-ALL-2000349 H+ [phagolysosome] R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1237045 https://reactome.org/PathwayBrowser/#/R-MMU-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1237047 https://reactome.org/PathwayBrowser/#/R-MMU-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1237059 https://reactome.org/PathwayBrowser/#/R-MMU-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1237081 https://reactome.org/PathwayBrowser/#/R-MMU-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1475017 https://reactome.org/PathwayBrowser/#/R-MMU-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1475022 https://reactome.org/PathwayBrowser/#/R-MMU-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-1475025 https://reactome.org/PathwayBrowser/#/R-MMU-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1475026 https://reactome.org/PathwayBrowser/#/R-MMU-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-1475028 https://reactome.org/PathwayBrowser/#/R-MMU-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-1475032 https://reactome.org/PathwayBrowser/#/R-MMU-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1475435 https://reactome.org/PathwayBrowser/#/R-MMU-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1475436 https://reactome.org/PathwayBrowser/#/R-MMU-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1497770 https://reactome.org/PathwayBrowser/#/R-MMU-1497770 Salvage - BH2 is reduced to BH4 by Dhfr TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1497869 https://reactome.org/PathwayBrowser/#/R-MMU-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-158609 https://reactome.org/PathwayBrowser/#/R-MMU-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-159790 https://reactome.org/PathwayBrowser/#/R-MMU-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-1605797 https://reactome.org/PathwayBrowser/#/R-MMU-1605797 SMPD1 hydrolyzes SPHM IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1606273 https://reactome.org/PathwayBrowser/#/R-MMU-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1606288 https://reactome.org/PathwayBrowser/#/R-MMU-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-1606807 https://reactome.org/PathwayBrowser/#/R-MMU-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-1614362 https://reactome.org/PathwayBrowser/#/R-MMU-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1614567 https://reactome.org/PathwayBrowser/#/R-MMU-1614567 Excess homocysteine yields homolanthionine and H2S IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1614591 https://reactome.org/PathwayBrowser/#/R-MMU-1614591 Excess cysteine yields lanthionine and H2S IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1614614 https://reactome.org/PathwayBrowser/#/R-MMU-1614614 Cysteine is degraded to pyruvate and H2S IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1614631 https://reactome.org/PathwayBrowser/#/R-MMU-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-162730 https://reactome.org/PathwayBrowser/#/R-MMU-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-163120 https://reactome.org/PathwayBrowser/#/R-MMU-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-163217 https://reactome.org/PathwayBrowser/#/R-MMU-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-1638104 https://reactome.org/PathwayBrowser/#/R-MMU-1638104 UGCG transfers glucose to ceramide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1638845 https://reactome.org/PathwayBrowser/#/R-MMU-1638845 CERK phosphorylates CERA to form C1P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1640164 https://reactome.org/PathwayBrowser/#/R-MMU-1640164 ENPP7 hydrolyzes sphingomyelin IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-164651 https://reactome.org/PathwayBrowser/#/R-MMU-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-164834 https://reactome.org/PathwayBrowser/#/R-MMU-164834 Enzyme-bound ATP is released IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-164834 https://reactome.org/PathwayBrowser/#/R-MMU-164834 Enzyme-bound ATP is released IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-1655879 https://reactome.org/PathwayBrowser/#/R-MMU-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Mus musculus 15378 R-ALL-9631150 H+ [endolysosome lumen] R-MMU-1678920 https://reactome.org/PathwayBrowser/#/R-MMU-1678920 TLR processing at low pH IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-169270 https://reactome.org/PathwayBrowser/#/R-MMU-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 UCP1 imports a proton IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-170026 https://reactome.org/PathwayBrowser/#/R-MMU-170026 UCP1 imports a proton IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-173597 https://reactome.org/PathwayBrowser/#/R-MMU-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-174389 https://reactome.org/PathwayBrowser/#/R-MMU-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-174392 https://reactome.org/PathwayBrowser/#/R-MMU-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-174438 https://reactome.org/PathwayBrowser/#/R-MMU-174438 Formation of the Flap Intermediate on the C-strand IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-189425 https://reactome.org/PathwayBrowser/#/R-MMU-189425 UROD decarboxylates URO3 to COPRO3 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-189439 https://reactome.org/PathwayBrowser/#/R-MMU-189439 ALAD condenses 2 dALAs to form PBG IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-189442 https://reactome.org/PathwayBrowser/#/R-MMU-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-189465 https://reactome.org/PathwayBrowser/#/R-MMU-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-190182 https://reactome.org/PathwayBrowser/#/R-MMU-190182 UROD decarboxylates URO1 to COPRO1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191323 https://reactome.org/PathwayBrowser/#/R-MMU-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191352 https://reactome.org/PathwayBrowser/#/R-MMU-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191402 https://reactome.org/PathwayBrowser/#/R-MMU-191402 Reduction of presqualene diphosphate to form squalene IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192033 https://reactome.org/PathwayBrowser/#/R-MMU-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192036 https://reactome.org/PathwayBrowser/#/R-MMU-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-192042 https://reactome.org/PathwayBrowser/#/R-MMU-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192067 https://reactome.org/PathwayBrowser/#/R-MMU-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192097 https://reactome.org/PathwayBrowser/#/R-MMU-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192160 https://reactome.org/PathwayBrowser/#/R-MMU-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193064 https://reactome.org/PathwayBrowser/#/R-MMU-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193073 https://reactome.org/PathwayBrowser/#/R-MMU-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-193455 https://reactome.org/PathwayBrowser/#/R-MMU-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193497 https://reactome.org/PathwayBrowser/#/R-MMU-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-193508 https://reactome.org/PathwayBrowser/#/R-MMU-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193746 https://reactome.org/PathwayBrowser/#/R-MMU-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193755 https://reactome.org/PathwayBrowser/#/R-MMU-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193758 https://reactome.org/PathwayBrowser/#/R-MMU-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193781 https://reactome.org/PathwayBrowser/#/R-MMU-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193789 https://reactome.org/PathwayBrowser/#/R-MMU-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193800 https://reactome.org/PathwayBrowser/#/R-MMU-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193816 https://reactome.org/PathwayBrowser/#/R-MMU-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193821 https://reactome.org/PathwayBrowser/#/R-MMU-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193824 https://reactome.org/PathwayBrowser/#/R-MMU-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193841 https://reactome.org/PathwayBrowser/#/R-MMU-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194023 https://reactome.org/PathwayBrowser/#/R-MMU-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194632 https://reactome.org/PathwayBrowser/#/R-MMU-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194642 https://reactome.org/PathwayBrowser/#/R-MMU-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-ALL-194688 H+ [nuclear envelope] R-MMU-194674 https://reactome.org/PathwayBrowser/#/R-MMU-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194689 https://reactome.org/PathwayBrowser/#/R-MMU-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194698 https://reactome.org/PathwayBrowser/#/R-MMU-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-194718 https://reactome.org/PathwayBrowser/#/R-MMU-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196060 https://reactome.org/PathwayBrowser/#/R-MMU-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196350 https://reactome.org/PathwayBrowser/#/R-MMU-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196372 https://reactome.org/PathwayBrowser/#/R-MMU-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196402 https://reactome.org/PathwayBrowser/#/R-MMU-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196417 https://reactome.org/PathwayBrowser/#/R-MMU-196417 Reduction of desmosterol to cholesterol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196753 https://reactome.org/PathwayBrowser/#/R-MMU-196753 2xPPCS ligates PPanK with Cys IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196754 https://reactome.org/PathwayBrowser/#/R-MMU-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196773 https://reactome.org/PathwayBrowser/#/R-MMU-196773 COASY phosphorylates DP-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196840 https://reactome.org/PathwayBrowser/#/R-MMU-196840 3xPPCDC:3FMN decarboxylates PPC IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196857 https://reactome.org/PathwayBrowser/#/R-MMU-196857 PANK2 phosphorylates PanK IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196929 https://reactome.org/PathwayBrowser/#/R-MMU-196929 FLAD1 phosphorylates FMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196955 https://reactome.org/PathwayBrowser/#/R-MMU-196955 2xENPP1 hydrolyzes FAD to FMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-196964 https://reactome.org/PathwayBrowser/#/R-MMU-196964 RFK:Mg2+ phosphorylates RIB IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197198 https://reactome.org/PathwayBrowser/#/R-MMU-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197235 https://reactome.org/PathwayBrowser/#/R-MMU-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197250 https://reactome.org/PathwayBrowser/#/R-MMU-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197268 https://reactome.org/PathwayBrowser/#/R-MMU-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197271 https://reactome.org/PathwayBrowser/#/R-MMU-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197963 https://reactome.org/PathwayBrowser/#/R-MMU-197963 DHFR2 reduces FOLA to DHF IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-197972 https://reactome.org/PathwayBrowser/#/R-MMU-197972 DHF is reduced to tetrahydrofolate (THF) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-198824 https://reactome.org/PathwayBrowser/#/R-MMU-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-199203 https://reactome.org/PathwayBrowser/#/R-MMU-199203 PANK1/3 phosphorylate PanK IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200423 https://reactome.org/PathwayBrowser/#/R-MMU-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-200474 https://reactome.org/PathwayBrowser/#/R-MMU-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-200512 https://reactome.org/PathwayBrowser/#/R-MMU-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200555 https://reactome.org/PathwayBrowser/#/R-MMU-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200644 https://reactome.org/PathwayBrowser/#/R-MMU-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200646 https://reactome.org/PathwayBrowser/#/R-MMU-200646 Cytosolic folate export across the plasma membrane IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-200646 https://reactome.org/PathwayBrowser/#/R-MMU-200646 Cytosolic folate export across the plasma membrane IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200676 https://reactome.org/PathwayBrowser/#/R-MMU-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200718 https://reactome.org/PathwayBrowser/#/R-MMU-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-200729 https://reactome.org/PathwayBrowser/#/R-MMU-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-200729 https://reactome.org/PathwayBrowser/#/R-MMU-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-202111 https://reactome.org/PathwayBrowser/#/R-MMU-202111 AKT1 phosphorylates eNOS IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-203613 https://reactome.org/PathwayBrowser/#/R-MMU-203613 Depalmitoylation of eNOS IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-203946 https://reactome.org/PathwayBrowser/#/R-MMU-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-204617 https://reactome.org/PathwayBrowser/#/R-MMU-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-204647 https://reactome.org/PathwayBrowser/#/R-MMU-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209772 https://reactome.org/PathwayBrowser/#/R-MMU-209772 Thyroxine is deiodinated to triiodothyronine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209821 https://reactome.org/PathwayBrowser/#/R-MMU-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-209903 https://reactome.org/PathwayBrowser/#/R-MMU-209903 Noradrenaline is converted to adrenaline IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-209973 https://reactome.org/PathwayBrowser/#/R-MMU-209973 Tyrosine is diiodinated IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-210404 https://reactome.org/PathwayBrowser/#/R-MMU-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161187 https://reactome.org/PathwayBrowser/#/R-MMU-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161549 https://reactome.org/PathwayBrowser/#/R-MMU-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161614 https://reactome.org/PathwayBrowser/#/R-MMU-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161638 https://reactome.org/PathwayBrowser/#/R-MMU-2161638 15k-PGE2/F2a is reduced to dhk-PGE2/F2a by Ptgr2 TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161651 https://reactome.org/PathwayBrowser/#/R-MMU-2161651 PGE2 is converted to PGF2a by CBR1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161779 https://reactome.org/PathwayBrowser/#/R-MMU-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2162078 https://reactome.org/PathwayBrowser/#/R-MMU-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162186 https://reactome.org/PathwayBrowser/#/R-MMU-2162186 COQ3 methylates DeMQ10H2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162187 https://reactome.org/PathwayBrowser/#/R-MMU-2162187 COQ6 hydroxylates DHB IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162188 https://reactome.org/PathwayBrowser/#/R-MMU-2162188 COQ5 methylates MDMQ10H2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162193 https://reactome.org/PathwayBrowser/#/R-MMU-2162193 COQ3 methylates DHDB IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2162195 https://reactome.org/PathwayBrowser/#/R-MMU-2162195 COQ4 decarboxylates MHDB IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2395512 https://reactome.org/PathwayBrowser/#/R-MMU-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2395517 https://reactome.org/PathwayBrowser/#/R-MMU-2395517 NADPH transfers electrons to FDXR IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395818 https://reactome.org/PathwayBrowser/#/R-MMU-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395849 https://reactome.org/PathwayBrowser/#/R-MMU-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395869 https://reactome.org/PathwayBrowser/#/R-MMU-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395872 https://reactome.org/PathwayBrowser/#/R-MMU-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395873 https://reactome.org/PathwayBrowser/#/R-MMU-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395876 https://reactome.org/PathwayBrowser/#/R-MMU-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395879 https://reactome.org/PathwayBrowser/#/R-MMU-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2395965 https://reactome.org/PathwayBrowser/#/R-MMU-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2408524 https://reactome.org/PathwayBrowser/#/R-MMU-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2453833 https://reactome.org/PathwayBrowser/#/R-MMU-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2454081 https://reactome.org/PathwayBrowser/#/R-MMU-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2464822 https://reactome.org/PathwayBrowser/#/R-MMU-2464822 RDH12 reduces atRAL to atROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2465940 https://reactome.org/PathwayBrowser/#/R-MMU-2465940 atRAL is reduced to atROL IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-2509793 https://reactome.org/PathwayBrowser/#/R-MMU-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-2509816 https://reactome.org/PathwayBrowser/#/R-MMU-2509816 NUDT16 hydrolyses IDP to IMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2509827 https://reactome.org/PathwayBrowser/#/R-MMU-2509827 ITPA hydrolyses ITP to IMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2509831 https://reactome.org/PathwayBrowser/#/R-MMU-2509831 ITPA hydrolyses XTP to XMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2509838 https://reactome.org/PathwayBrowser/#/R-MMU-2509838 ITPA hydrolyses dITP to dIMP IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-2534378 https://reactome.org/PathwayBrowser/#/R-MMU-2534378 Hv1 Mediated H+ Permeability IEA Mus musculus 15378 R-ALL-1132304 H+ [cytoplasm] R-MMU-2534378 https://reactome.org/PathwayBrowser/#/R-MMU-2534378 Hv1 Mediated H+ Permeability IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-MMU-264615 https://reactome.org/PathwayBrowser/#/R-MMU-264615 Loading of acetylcholine in synaptic vesicles IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-266070 https://reactome.org/PathwayBrowser/#/R-MMU-266070 LTC4 is exported from the cytosol by ABCC1 IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-2671885 https://reactome.org/PathwayBrowser/#/R-MMU-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2730692 https://reactome.org/PathwayBrowser/#/R-MMU-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Mus musculus 15378 R-ALL-74722 H+ [endosome lumen] R-MMU-2730692 https://reactome.org/PathwayBrowser/#/R-MMU-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2730951 https://reactome.org/PathwayBrowser/#/R-MMU-2730951 Clcn3 exchanges Cl- for H+ TAS Mus musculus 15378 R-ALL-425999 H+ [late endosome lumen] R-MMU-2730951 https://reactome.org/PathwayBrowser/#/R-MMU-2730951 Clcn3 exchanges Cl- for H+ TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2730959 https://reactome.org/PathwayBrowser/#/R-MMU-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-2730959 https://reactome.org/PathwayBrowser/#/R-MMU-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2855252 https://reactome.org/PathwayBrowser/#/R-MMU-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-2872444 https://reactome.org/PathwayBrowser/#/R-MMU-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-2872444 https://reactome.org/PathwayBrowser/#/R-MMU-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-2872452 https://reactome.org/PathwayBrowser/#/R-MMU-2872452 Slc9c1 exchanges Na+ for H+ TAS Mus musculus 15378 R-ALL-2872447 H+ [sperm flagellum] R-MMU-2872452 https://reactome.org/PathwayBrowser/#/R-MMU-2872452 Slc9c1 exchanges Na+ for H+ TAS Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-2889070 https://reactome.org/PathwayBrowser/#/R-MMU-2889070 SLC9B2 exchanges Na+ for H+ IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-2889070 https://reactome.org/PathwayBrowser/#/R-MMU-2889070 SLC9B2 exchanges Na+ for H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3095889 https://reactome.org/PathwayBrowser/#/R-MMU-3095889 MMACHC dealkylates RCbl IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3149518 https://reactome.org/PathwayBrowser/#/R-MMU-3149518 MTRR reduces cob(II)alamin to meCbl IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3149519 https://reactome.org/PathwayBrowser/#/R-MMU-3149519 MMACHC decyanates CNCbl IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-3159253 https://reactome.org/PathwayBrowser/#/R-MMU-3159253 MMAB adenosylates cob(I)alamin IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3322001 https://reactome.org/PathwayBrowser/#/R-MMU-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3322003 https://reactome.org/PathwayBrowser/#/R-MMU-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3322025 https://reactome.org/PathwayBrowser/#/R-MMU-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3322041 https://reactome.org/PathwayBrowser/#/R-MMU-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-3323050 https://reactome.org/PathwayBrowser/#/R-MMU-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-3323079 https://reactome.org/PathwayBrowser/#/R-MMU-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-350869 https://reactome.org/PathwayBrowser/#/R-MMU-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-350901 https://reactome.org/PathwayBrowser/#/R-MMU-350901 Iodide is organified IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-352174 https://reactome.org/PathwayBrowser/#/R-MMU-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-352182 https://reactome.org/PathwayBrowser/#/R-MMU-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-372448 https://reactome.org/PathwayBrowser/#/R-MMU-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-373867 https://reactome.org/PathwayBrowser/#/R-MMU-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-373875 https://reactome.org/PathwayBrowser/#/R-MMU-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-375405 https://reactome.org/PathwayBrowser/#/R-MMU-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-375405 https://reactome.org/PathwayBrowser/#/R-MMU-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-375417 https://reactome.org/PathwayBrowser/#/R-MMU-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-3781024 https://reactome.org/PathwayBrowser/#/R-MMU-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-379048 https://reactome.org/PathwayBrowser/#/R-MMU-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-380608 https://reactome.org/PathwayBrowser/#/R-MMU-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-389540 https://reactome.org/PathwayBrowser/#/R-MMU-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-389550 https://reactome.org/PathwayBrowser/#/R-MMU-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-389609 https://reactome.org/PathwayBrowser/#/R-MMU-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-389826 https://reactome.org/PathwayBrowser/#/R-MMU-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-389995 https://reactome.org/PathwayBrowser/#/R-MMU-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-390251 https://reactome.org/PathwayBrowser/#/R-MMU-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-390304 https://reactome.org/PathwayBrowser/#/R-MMU-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-390393 https://reactome.org/PathwayBrowser/#/R-MMU-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-390425 https://reactome.org/PathwayBrowser/#/R-MMU-390425 FAR1 reduces PalmCoA to HXOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-390438 https://reactome.org/PathwayBrowser/#/R-MMU-390438 FAR2 reduces PalmCoA to HXOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-418365 https://reactome.org/PathwayBrowser/#/R-MMU-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Mus musculus 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-MMU-418365 https://reactome.org/PathwayBrowser/#/R-MMU-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-425577 https://reactome.org/PathwayBrowser/#/R-MMU-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-425965 https://reactome.org/PathwayBrowser/#/R-MMU-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Mus musculus 15378 R-ALL-425999 H+ [late endosome lumen] R-MMU-425965 https://reactome.org/PathwayBrowser/#/R-MMU-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-425983 https://reactome.org/PathwayBrowser/#/R-MMU-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Mus musculus 15378 R-ALL-425978 H+ [early endosome lumen] R-MMU-425983 https://reactome.org/PathwayBrowser/#/R-MMU-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-425994 https://reactome.org/PathwayBrowser/#/R-MMU-425994 Na+/H+ exchanger transport (at cell membrane) IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-425994 https://reactome.org/PathwayBrowser/#/R-MMU-425994 Na+/H+ exchanger transport (at cell membrane) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-426015 https://reactome.org/PathwayBrowser/#/R-MMU-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-426015 https://reactome.org/PathwayBrowser/#/R-MMU-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-426043 https://reactome.org/PathwayBrowser/#/R-MMU-426043 2-AG hydrolysis to arachidonate by MAGL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-427555 https://reactome.org/PathwayBrowser/#/R-MMU-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-427555 https://reactome.org/PathwayBrowser/#/R-MMU-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-427910 https://reactome.org/PathwayBrowser/#/R-MMU-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-427910 https://reactome.org/PathwayBrowser/#/R-MMU-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-427998 https://reactome.org/PathwayBrowser/#/R-MMU-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-428007 https://reactome.org/PathwayBrowser/#/R-MMU-428007 Proton-coupled histidine and di-peptide cotransport IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-428015 https://reactome.org/PathwayBrowser/#/R-MMU-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428052 https://reactome.org/PathwayBrowser/#/R-MMU-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Mus musculus 15378 R-ALL-428548 H+ [synaptic vesicle] R-MMU-428052 https://reactome.org/PathwayBrowser/#/R-MMU-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428123 https://reactome.org/PathwayBrowser/#/R-MMU-428123 KDSR reduces 3-ketosphingoid IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428127 https://reactome.org/PathwayBrowser/#/R-MMU-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428185 https://reactome.org/PathwayBrowser/#/R-MMU-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428273 https://reactome.org/PathwayBrowser/#/R-MMU-428273 SPHK1 phosphorylates sphingoid IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428585 https://reactome.org/PathwayBrowser/#/R-MMU-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-428585 https://reactome.org/PathwayBrowser/#/R-MMU-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-428625 https://reactome.org/PathwayBrowser/#/R-MMU-428625 Vesicular inhibitory amino acid transport IEA Mus musculus 15378 R-ALL-428548 H+ [synaptic vesicle] R-MMU-428625 https://reactome.org/PathwayBrowser/#/R-MMU-428625 Vesicular inhibitory amino acid transport IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-429016 https://reactome.org/PathwayBrowser/#/R-MMU-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-429101 https://reactome.org/PathwayBrowser/#/R-MMU-429101 HMIT co-transports myo-inositol with a proton IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-429101 https://reactome.org/PathwayBrowser/#/R-MMU-429101 HMIT co-transports myo-inositol with a proton IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-429157 https://reactome.org/PathwayBrowser/#/R-MMU-429157 ABCC4 accumulation of dense granule contents IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-433698 https://reactome.org/PathwayBrowser/#/R-MMU-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-434650 https://reactome.org/PathwayBrowser/#/R-MMU-434650 MATEs mediate extrusion of xenobiotics IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-435171 https://reactome.org/PathwayBrowser/#/R-MMU-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-435349 https://reactome.org/PathwayBrowser/#/R-MMU-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-435349 https://reactome.org/PathwayBrowser/#/R-MMU-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-444393 https://reactome.org/PathwayBrowser/#/R-MMU-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-444393 https://reactome.org/PathwayBrowser/#/R-MMU-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-444419 https://reactome.org/PathwayBrowser/#/R-MMU-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-444419 https://reactome.org/PathwayBrowser/#/R-MMU-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-444731 https://reactome.org/PathwayBrowser/#/R-MMU-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-446195 https://reactome.org/PathwayBrowser/#/R-MMU-446195 DOLK phosphorylates DCHOL to DOLP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-446200 https://reactome.org/PathwayBrowser/#/R-MMU-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-446221 https://reactome.org/PathwayBrowser/#/R-MMU-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-446277 https://reactome.org/PathwayBrowser/#/R-MMU-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-446277 https://reactome.org/PathwayBrowser/#/R-MMU-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-446278 https://reactome.org/PathwayBrowser/#/R-MMU-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-446278 https://reactome.org/PathwayBrowser/#/R-MMU-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-450971 https://reactome.org/PathwayBrowser/#/R-MMU-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-469659 https://reactome.org/PathwayBrowser/#/R-MMU-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-504054 https://reactome.org/PathwayBrowser/#/R-MMU-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-508040 https://reactome.org/PathwayBrowser/#/R-MMU-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-508308 https://reactome.org/PathwayBrowser/#/R-MMU-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-508369 https://reactome.org/PathwayBrowser/#/R-MMU-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-508473 https://reactome.org/PathwayBrowser/#/R-MMU-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-514604 https://reactome.org/PathwayBrowser/#/R-MMU-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5263614 https://reactome.org/PathwayBrowser/#/R-MMU-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5263616 https://reactome.org/PathwayBrowser/#/R-MMU-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5340130 https://reactome.org/PathwayBrowser/#/R-MMU-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-5340130 https://reactome.org/PathwayBrowser/#/R-MMU-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5362518 https://reactome.org/PathwayBrowser/#/R-MMU-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5362522 https://reactome.org/PathwayBrowser/#/R-MMU-5362522 ALDHs oxidise atRAL to atRA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5362564 https://reactome.org/PathwayBrowser/#/R-MMU-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5362721 https://reactome.org/PathwayBrowser/#/R-MMU-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5419165 https://reactome.org/PathwayBrowser/#/R-MMU-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5423637 https://reactome.org/PathwayBrowser/#/R-MMU-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548800 https://reactome.org/PathwayBrowser/#/R-MMU-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548814 https://reactome.org/PathwayBrowser/#/R-MMU-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548815 https://reactome.org/PathwayBrowser/#/R-MMU-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548818 https://reactome.org/PathwayBrowser/#/R-MMU-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548831 https://reactome.org/PathwayBrowser/#/R-MMU-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-548848 https://reactome.org/PathwayBrowser/#/R-MMU-548848 lignoceroyl-CoA + malonyl-CoA => 3-oxocerotoyl-CoA + CO2 + CoASH [Elovl4] TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5615668 https://reactome.org/PathwayBrowser/#/R-MMU-5615668 AKR1C3 reduces atRAL to atROL IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-5623643 https://reactome.org/PathwayBrowser/#/R-MMU-5623643 RDH13 reduces atRAL to atROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5652172 https://reactome.org/PathwayBrowser/#/R-MMU-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5652195 https://reactome.org/PathwayBrowser/#/R-MMU-5652195 SORD oxidizes D-sorbitol to Fru IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5661240 https://reactome.org/PathwayBrowser/#/R-MMU-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5661256 https://reactome.org/PathwayBrowser/#/R-MMU-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5661290 https://reactome.org/PathwayBrowser/#/R-MMU-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5662471 https://reactome.org/PathwayBrowser/#/R-MMU-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Mus musculus 15378 R-ALL-5668577 H+ [melanosome lumen] R-MMU-5662662 https://reactome.org/PathwayBrowser/#/R-MMU-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-5690042 https://reactome.org/PathwayBrowser/#/R-MMU-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-5690046 https://reactome.org/PathwayBrowser/#/R-MMU-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Mus musculus 15378 R-ALL-428040 H+ [lysosomal lumen] R-MMU-5690517 https://reactome.org/PathwayBrowser/#/R-MMU-5690517 PPT1 hydrolyses palmitoylated proteins IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5692237 https://reactome.org/PathwayBrowser/#/R-MMU-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5692261 https://reactome.org/PathwayBrowser/#/R-MMU-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5692283 https://reactome.org/PathwayBrowser/#/R-MMU-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5693148 https://reactome.org/PathwayBrowser/#/R-MMU-5693148 BCKDK phosphorylates BCKDH IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-5693347 https://reactome.org/PathwayBrowser/#/R-MMU-5693347 CRYM reduces P2C to PPCA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5693390 https://reactome.org/PathwayBrowser/#/R-MMU-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-5693691 https://reactome.org/PathwayBrowser/#/R-MMU-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5693967 https://reactome.org/PathwayBrowser/#/R-MMU-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5694018 https://reactome.org/PathwayBrowser/#/R-MMU-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5694462 https://reactome.org/PathwayBrowser/#/R-MMU-5694462 ABHD6,12 hydrolyse 3AG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5696021 https://reactome.org/PathwayBrowser/#/R-MMU-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5696080 https://reactome.org/PathwayBrowser/#/R-MMU-5696080 ALDH3B1 oxidises HXAL to PALM IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5696091 https://reactome.org/PathwayBrowser/#/R-MMU-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5696101 https://reactome.org/PathwayBrowser/#/R-MMU-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5696457 https://reactome.org/PathwayBrowser/#/R-MMU-5696457 BDH2 dehydrogenates 3HBA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-5696822 https://reactome.org/PathwayBrowser/#/R-MMU-5696822 AKR1B15 reduces EST17b to E1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-5696838 https://reactome.org/PathwayBrowser/#/R-MMU-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-597628 https://reactome.org/PathwayBrowser/#/R-MMU-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6783221 https://reactome.org/PathwayBrowser/#/R-MMU-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6783939 https://reactome.org/PathwayBrowser/#/R-MMU-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6783955 https://reactome.org/PathwayBrowser/#/R-MMU-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6784224 https://reactome.org/PathwayBrowser/#/R-MMU-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6784402 https://reactome.org/PathwayBrowser/#/R-MMU-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-6785933 https://reactome.org/PathwayBrowser/#/R-MMU-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6786245 https://reactome.org/PathwayBrowser/#/R-MMU-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6786720 https://reactome.org/PathwayBrowser/#/R-MMU-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6787642 https://reactome.org/PathwayBrowser/#/R-MMU-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6787757 https://reactome.org/PathwayBrowser/#/R-MMU-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6788611 https://reactome.org/PathwayBrowser/#/R-MMU-6788611 HYKK phosphorylates 5HLYS IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6788999 https://reactome.org/PathwayBrowser/#/R-MMU-6788999 HV1-mediated H+ transfer IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-6788999 https://reactome.org/PathwayBrowser/#/R-MMU-6788999 HV1-mediated H+ transfer IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-6789031 https://reactome.org/PathwayBrowser/#/R-MMU-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-6789126 https://reactome.org/PathwayBrowser/#/R-MMU-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6793590 https://reactome.org/PathwayBrowser/#/R-MMU-6793590 LIPT2 transfers octanoyl group to GCSH IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6793591 https://reactome.org/PathwayBrowser/#/R-MMU-6793591 LIAS synthesizes lipoyl-GCSH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6798317 https://reactome.org/PathwayBrowser/#/R-MMU-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6798335 https://reactome.org/PathwayBrowser/#/R-MMU-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6799495 https://reactome.org/PathwayBrowser/#/R-MMU-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6801342 https://reactome.org/PathwayBrowser/#/R-MMU-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6803771 https://reactome.org/PathwayBrowser/#/R-MMU-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-6806647 https://reactome.org/PathwayBrowser/#/R-MMU-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6806831 https://reactome.org/PathwayBrowser/#/R-MMU-6806831 CYB5Rs reduce MetHb to HbA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6806967 https://reactome.org/PathwayBrowser/#/R-MMU-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6807055 https://reactome.org/PathwayBrowser/#/R-MMU-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6807064 https://reactome.org/PathwayBrowser/#/R-MMU-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6807826 https://reactome.org/PathwayBrowser/#/R-MMU-6807826 LDHAL6B reduces PYR to LACT IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6808464 https://reactome.org/PathwayBrowser/#/R-MMU-6808464 ALDH3B2 oxidises HXAL to PALM IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-6808487 https://reactome.org/PathwayBrowser/#/R-MMU-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6808496 https://reactome.org/PathwayBrowser/#/R-MMU-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6809264 https://reactome.org/PathwayBrowser/#/R-MMU-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6809287 https://reactome.org/PathwayBrowser/#/R-MMU-6809287 NUDT12 hydrolyses NADH to NMNH IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6809810 https://reactome.org/PathwayBrowser/#/R-MMU-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-6810474 https://reactome.org/PathwayBrowser/#/R-MMU-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6810594 https://reactome.org/PathwayBrowser/#/R-MMU-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6813749 https://reactome.org/PathwayBrowser/#/R-MMU-6813749 ALDH1A1 oxidises GA to DGA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-6814165 https://reactome.org/PathwayBrowser/#/R-MMU-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70286 https://reactome.org/PathwayBrowser/#/R-MMU-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70333 https://reactome.org/PathwayBrowser/#/R-MMU-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70355 https://reactome.org/PathwayBrowser/#/R-MMU-70355 GALK1 phosphorylates Gal to Gal1P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70377 https://reactome.org/PathwayBrowser/#/R-MMU-70377 G6PD multimers dehydrogenate G6P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70420 https://reactome.org/PathwayBrowser/#/R-MMU-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70449 https://reactome.org/PathwayBrowser/#/R-MMU-70449 GADPH tetramer dehydrogenates GA3P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70467 https://reactome.org/PathwayBrowser/#/R-MMU-70467 PFK tetramer phosphorylates Fru(6)P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70482 https://reactome.org/PathwayBrowser/#/R-MMU-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70501 https://reactome.org/PathwayBrowser/#/R-MMU-70501 PC carboxylates PYR to OA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70510 https://reactome.org/PathwayBrowser/#/R-MMU-70510 LDH tetramer oxidises LACT to PYR IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70589 https://reactome.org/PathwayBrowser/#/R-MMU-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70599 https://reactome.org/PathwayBrowser/#/R-MMU-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70600 https://reactome.org/PathwayBrowser/#/R-MMU-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-70606 https://reactome.org/PathwayBrowser/#/R-MMU-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70664 https://reactome.org/PathwayBrowser/#/R-MMU-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70670 https://reactome.org/PathwayBrowser/#/R-MMU-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70679 https://reactome.org/PathwayBrowser/#/R-MMU-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70745 https://reactome.org/PathwayBrowser/#/R-MMU-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70773 https://reactome.org/PathwayBrowser/#/R-MMU-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70800 https://reactome.org/PathwayBrowser/#/R-MMU-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70837 https://reactome.org/PathwayBrowser/#/R-MMU-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70859 https://reactome.org/PathwayBrowser/#/R-MMU-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70881 https://reactome.org/PathwayBrowser/#/R-MMU-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70885 https://reactome.org/PathwayBrowser/#/R-MMU-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70893 https://reactome.org/PathwayBrowser/#/R-MMU-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70938 https://reactome.org/PathwayBrowser/#/R-MMU-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70940 https://reactome.org/PathwayBrowser/#/R-MMU-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70941 https://reactome.org/PathwayBrowser/#/R-MMU-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70975 https://reactome.org/PathwayBrowser/#/R-MMU-70975 CS acetylates OA to citrate IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-70979 https://reactome.org/PathwayBrowser/#/R-MMU-70979 MDH2 dimer dehydrogenates MAL IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-71046 https://reactome.org/PathwayBrowser/#/R-MMU-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71130 https://reactome.org/PathwayBrowser/#/R-MMU-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71181 https://reactome.org/PathwayBrowser/#/R-MMU-71181 FAH cleaves 4FAA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71217 https://reactome.org/PathwayBrowser/#/R-MMU-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71260 https://reactome.org/PathwayBrowser/#/R-MMU-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71286 https://reactome.org/PathwayBrowser/#/R-MMU-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71296 https://reactome.org/PathwayBrowser/#/R-MMU-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-71401 https://reactome.org/PathwayBrowser/#/R-MMU-71401 OGDH dimer decarboxylates 2-OG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71541 https://reactome.org/PathwayBrowser/#/R-MMU-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71588 https://reactome.org/PathwayBrowser/#/R-MMU-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71670 https://reactome.org/PathwayBrowser/#/R-MMU-71670 PKM dephosphorylates PEP to PYR IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71682 https://reactome.org/PathwayBrowser/#/R-MMU-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71691 https://reactome.org/PathwayBrowser/#/R-MMU-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71707 https://reactome.org/PathwayBrowser/#/R-MMU-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-71723 https://reactome.org/PathwayBrowser/#/R-MMU-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71802 https://reactome.org/PathwayBrowser/#/R-MMU-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-71849 https://reactome.org/PathwayBrowser/#/R-MMU-71849 LDH tetramer reduces PYR to LACT IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73564 https://reactome.org/PathwayBrowser/#/R-MMU-73564 UMPS dimer decarboxylates OMP to UMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73571 https://reactome.org/PathwayBrowser/#/R-MMU-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73573 https://reactome.org/PathwayBrowser/#/R-MMU-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73577 https://reactome.org/PathwayBrowser/#/R-MMU-73577 CAD hexamer transforms L-Gln to CAP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73580 https://reactome.org/PathwayBrowser/#/R-MMU-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73585 https://reactome.org/PathwayBrowser/#/R-MMU-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73589 https://reactome.org/PathwayBrowser/#/R-MMU-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73591 https://reactome.org/PathwayBrowser/#/R-MMU-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73596 https://reactome.org/PathwayBrowser/#/R-MMU-73596 dCMP + H2O => dUMP + NH4+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73616 https://reactome.org/PathwayBrowser/#/R-MMU-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73618 https://reactome.org/PathwayBrowser/#/R-MMU-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73620 https://reactome.org/PathwayBrowser/#/R-MMU-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73646 https://reactome.org/PathwayBrowser/#/R-MMU-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73647 https://reactome.org/PathwayBrowser/#/R-MMU-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-73666 https://reactome.org/PathwayBrowser/#/R-MMU-73666 dUTP + H2O => dUMP + pyrophosphate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73792 https://reactome.org/PathwayBrowser/#/R-MMU-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73794 https://reactome.org/PathwayBrowser/#/R-MMU-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73805 https://reactome.org/PathwayBrowser/#/R-MMU-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73806 https://reactome.org/PathwayBrowser/#/R-MMU-73806 AIR + CO2 => CAIR IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73810 https://reactome.org/PathwayBrowser/#/R-MMU-73810 FGAM + ATP => AIR + ADP + Pi IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73812 https://reactome.org/PathwayBrowser/#/R-MMU-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73813 https://reactome.org/PathwayBrowser/#/R-MMU-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-73814 https://reactome.org/PathwayBrowser/#/R-MMU-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-73912 https://reactome.org/PathwayBrowser/#/R-MMU-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-73920 https://reactome.org/PathwayBrowser/#/R-MMU-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-74255 https://reactome.org/PathwayBrowser/#/R-MMU-74255 Guanine + H2O => Xanthine + NH4+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-74723 https://reactome.org/PathwayBrowser/#/R-MMU-74723 Endosome acidification IEA Mus musculus 15378 R-ALL-74722 H+ [endosome lumen] R-MMU-74723 https://reactome.org/PathwayBrowser/#/R-MMU-74723 Endosome acidification IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-74872 https://reactome.org/PathwayBrowser/#/R-MMU-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-749448 https://reactome.org/PathwayBrowser/#/R-MMU-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-749452 https://reactome.org/PathwayBrowser/#/R-MMU-749452 The Ligand:GPCR:Gq complex dissociates IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-75851 https://reactome.org/PathwayBrowser/#/R-MMU-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-75872 https://reactome.org/PathwayBrowser/#/R-MMU-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-75883 https://reactome.org/PathwayBrowser/#/R-MMU-75883 DHRS7B reduces GO3P to HXDG3P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-75889 https://reactome.org/PathwayBrowser/#/R-MMU-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77254 https://reactome.org/PathwayBrowser/#/R-MMU-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77283 https://reactome.org/PathwayBrowser/#/R-MMU-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77303 https://reactome.org/PathwayBrowser/#/R-MMU-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77312 https://reactome.org/PathwayBrowser/#/R-MMU-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77323 https://reactome.org/PathwayBrowser/#/R-MMU-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77331 https://reactome.org/PathwayBrowser/#/R-MMU-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-77342 https://reactome.org/PathwayBrowser/#/R-MMU-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-804969 https://reactome.org/PathwayBrowser/#/R-MMU-804969 HSD17B1 hydrogenates E1 to EST17b IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8849638 https://reactome.org/PathwayBrowser/#/R-MMU-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8850846 https://reactome.org/PathwayBrowser/#/R-MMU-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8850854 https://reactome.org/PathwayBrowser/#/R-MMU-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851089 https://reactome.org/PathwayBrowser/#/R-MMU-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851110 https://reactome.org/PathwayBrowser/#/R-MMU-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851129 https://reactome.org/PathwayBrowser/#/R-MMU-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-8851225 https://reactome.org/PathwayBrowser/#/R-MMU-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-8851234 https://reactome.org/PathwayBrowser/#/R-MMU-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851356 https://reactome.org/PathwayBrowser/#/R-MMU-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851396 https://reactome.org/PathwayBrowser/#/R-MMU-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-MMU-8851494 https://reactome.org/PathwayBrowser/#/R-MMU-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851538 https://reactome.org/PathwayBrowser/#/R-MMU-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8851550 https://reactome.org/PathwayBrowser/#/R-MMU-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-8856223 https://reactome.org/PathwayBrowser/#/R-MMU-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8862137 https://reactome.org/PathwayBrowser/#/R-MMU-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8862152 https://reactome.org/PathwayBrowser/#/R-MMU-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8863494 https://reactome.org/PathwayBrowser/#/R-MMU-8863494 ASICs bind STOML3, (STOM) IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-8863761 https://reactome.org/PathwayBrowser/#/R-MMU-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-8866601 https://reactome.org/PathwayBrowser/#/R-MMU-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8869606 https://reactome.org/PathwayBrowser/#/R-MMU-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8869607 https://reactome.org/PathwayBrowser/#/R-MMU-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8869627 https://reactome.org/PathwayBrowser/#/R-MMU-8869627 NMRK2 phosphorylates NR to yield NMN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8869633 https://reactome.org/PathwayBrowser/#/R-MMU-8869633 NMRK1 phosphorylates NR to yield NMN IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8870346 https://reactome.org/PathwayBrowser/#/R-MMU-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8875623 https://reactome.org/PathwayBrowser/#/R-MMU-8875623 SLC25A18,22 import L-Glu, H+ IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8875623 https://reactome.org/PathwayBrowser/#/R-MMU-8875623 SLC25A18,22 import L-Glu, H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8876789 https://reactome.org/PathwayBrowser/#/R-MMU-8876789 CARNMT1 methylates CARN to Anserine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8876889 https://reactome.org/PathwayBrowser/#/R-MMU-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-8878914 https://reactome.org/PathwayBrowser/#/R-MMU-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-888548 https://reactome.org/PathwayBrowser/#/R-MMU-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-888572 https://reactome.org/PathwayBrowser/#/R-MMU-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-888577 https://reactome.org/PathwayBrowser/#/R-MMU-888577 Synthesis of GABA by GAD2 IEA Mus musculus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-MMU-8933635 https://reactome.org/PathwayBrowser/#/R-MMU-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8936442 https://reactome.org/PathwayBrowser/#/R-MMU-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8938076 https://reactome.org/PathwayBrowser/#/R-MMU-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8939959 https://reactome.org/PathwayBrowser/#/R-MMU-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8940070 https://reactome.org/PathwayBrowser/#/R-MMU-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8942575 https://reactome.org/PathwayBrowser/#/R-MMU-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8951834 https://reactome.org/PathwayBrowser/#/R-MMU-8951834 Letm1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-8951834 https://reactome.org/PathwayBrowser/#/R-MMU-8951834 Letm1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix) TAS Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8952873 https://reactome.org/PathwayBrowser/#/R-MMU-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8954468 https://reactome.org/PathwayBrowser/#/R-MMU-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-8955030 https://reactome.org/PathwayBrowser/#/R-MMU-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8955760 https://reactome.org/PathwayBrowser/#/R-MMU-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8955844 https://reactome.org/PathwayBrowser/#/R-MMU-8955844 RBKS phosphorylates ribose to R5P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8956439 https://reactome.org/PathwayBrowser/#/R-MMU-8956439 Retsat reduces atROL to at-13,14-dhROL TAS Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8959510 https://reactome.org/PathwayBrowser/#/R-MMU-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-8959719 https://reactome.org/PathwayBrowser/#/R-MMU-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9009950 https://reactome.org/PathwayBrowser/#/R-MMU-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9011595 https://reactome.org/PathwayBrowser/#/R-MMU-9011595 GSTZ1 dimer dehalogenates DCA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9012016 https://reactome.org/PathwayBrowser/#/R-MMU-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9012036 https://reactome.org/PathwayBrowser/#/R-MMU-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-9013198 https://reactome.org/PathwayBrowser/#/R-MMU-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9024766 https://reactome.org/PathwayBrowser/#/R-MMU-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15378 R-ALL-74722 H+ [endosome lumen] R-MMU-917811 https://reactome.org/PathwayBrowser/#/R-MMU-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 15378 R-ALL-74722 H+ [endosome lumen] R-MMU-917841 https://reactome.org/PathwayBrowser/#/R-MMU-917841 Acidification of Tf:TfR1 containing endosome IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-917979 https://reactome.org/PathwayBrowser/#/R-MMU-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-937311 https://reactome.org/PathwayBrowser/#/R-MMU-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9619024 https://reactome.org/PathwayBrowser/#/R-MMU-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-9645220 https://reactome.org/PathwayBrowser/#/R-MMU-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-9650165 https://reactome.org/PathwayBrowser/#/R-MMU-9650165 ASIC trimers bind H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9695949 https://reactome.org/PathwayBrowser/#/R-MMU-9695949 SPHK2 phosphorylates sphingoid IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9705713 https://reactome.org/PathwayBrowser/#/R-MMU-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9705714 https://reactome.org/PathwayBrowser/#/R-MMU-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9709098 https://reactome.org/PathwayBrowser/#/R-MMU-9709098 DHFR dimer reduces FOLA to DHF IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-9727198 https://reactome.org/PathwayBrowser/#/R-MMU-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9727347 https://reactome.org/PathwayBrowser/#/R-MMU-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9727349 https://reactome.org/PathwayBrowser/#/R-MMU-9727349 XDH dehydrogenates xanthine to form urate IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9729538 https://reactome.org/PathwayBrowser/#/R-MMU-9729538 Otop1 transports H+ from the extracellular region to the cytosol TAS Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-9729538 https://reactome.org/PathwayBrowser/#/R-MMU-9729538 Otop1 transports H+ from the extracellular region to the cytosol TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9729881 https://reactome.org/PathwayBrowser/#/R-MMU-9729881 Kcnj2 transports K+ from the extracellular region to the cytosol TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9731228 https://reactome.org/PathwayBrowser/#/R-MMU-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9731590 https://reactome.org/PathwayBrowser/#/R-MMU-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9731613 https://reactome.org/PathwayBrowser/#/R-MMU-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9731632 https://reactome.org/PathwayBrowser/#/R-MMU-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9731661 https://reactome.org/PathwayBrowser/#/R-MMU-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9748945 https://reactome.org/PathwayBrowser/#/R-MMU-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9748957 https://reactome.org/PathwayBrowser/#/R-MMU-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9748979 https://reactome.org/PathwayBrowser/#/R-MMU-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9748983 https://reactome.org/PathwayBrowser/#/R-MMU-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9748991 https://reactome.org/PathwayBrowser/#/R-MMU-9748991 XDH oxidises 6MP to 6TU IEA Mus musculus 15378 R-ALL-351626 H+ [extracellular region] R-MMU-9749609 https://reactome.org/PathwayBrowser/#/R-MMU-9749609 BCHE hydrolyzes ASA- IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9749647 https://reactome.org/PathwayBrowser/#/R-MMU-9749647 CES2 hydrolyzes ASA- IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9749792 https://reactome.org/PathwayBrowser/#/R-MMU-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9755937 https://reactome.org/PathwayBrowser/#/R-MMU-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756134 https://reactome.org/PathwayBrowser/#/R-MMU-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756156 https://reactome.org/PathwayBrowser/#/R-MMU-9756156 UGT1A3 lactonizes ATV to ATVL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756177 https://reactome.org/PathwayBrowser/#/R-MMU-9756177 PON1,3 hydrolyse ATVL to ATV IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9756183 https://reactome.org/PathwayBrowser/#/R-MMU-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-975629 https://reactome.org/PathwayBrowser/#/R-MMU-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9757706 https://reactome.org/PathwayBrowser/#/R-MMU-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9758661 https://reactome.org/PathwayBrowser/#/R-MMU-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9758682 https://reactome.org/PathwayBrowser/#/R-MMU-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9759259 https://reactome.org/PathwayBrowser/#/R-MMU-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9759549 https://reactome.org/PathwayBrowser/#/R-MMU-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9760094 https://reactome.org/PathwayBrowser/#/R-MMU-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-977301 https://reactome.org/PathwayBrowser/#/R-MMU-977301 Histidine is decarboxylated to histamine IEA Mus musculus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-MMU-977317 https://reactome.org/PathwayBrowser/#/R-MMU-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-977348 https://reactome.org/PathwayBrowser/#/R-MMU-977348 PHGDH tetramer dehydrogenates 3PG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9773976 https://reactome.org/PathwayBrowser/#/R-MMU-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9794270 https://reactome.org/PathwayBrowser/#/R-MMU-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-9822592 https://reactome.org/PathwayBrowser/#/R-MMU-9822592 Mettl23 dimethylates histone H3.3 arginine-18 (arginine-17 in the mature protein) TAS Mus musculus 15378 R-ALL-9668967 H+ [nucleoplasm] R-MMU-9825790 https://reactome.org/PathwayBrowser/#/R-MMU-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9837337 https://reactome.org/PathwayBrowser/#/R-MMU-9837337 DCAKD phosphorylates DP-CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9837342 https://reactome.org/PathwayBrowser/#/R-MMU-9837342 Nudt8 hydrolyzes CoA-SH to PPANT TAS Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9843721 https://reactome.org/PathwayBrowser/#/R-MMU-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9844587 https://reactome.org/PathwayBrowser/#/R-MMU-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9844860 https://reactome.org/PathwayBrowser/#/R-MMU-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9845516 https://reactome.org/PathwayBrowser/#/R-MMU-9845516 B3GALT4 transfers Gal to gangliosides IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9845538 https://reactome.org/PathwayBrowser/#/R-MMU-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9845587 https://reactome.org/PathwayBrowser/#/R-MMU-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9846305 https://reactome.org/PathwayBrowser/#/R-MMU-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9846332 https://reactome.org/PathwayBrowser/#/R-MMU-9846332 FUT1,2 transfer fucose to gangliosides IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9846477 https://reactome.org/PathwayBrowser/#/R-MMU-9846477 A4GALT transfers galactose to LacCer IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9846501 https://reactome.org/PathwayBrowser/#/R-MMU-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Mus musculus 15378 R-ALL-425969 H+ [Golgi lumen] R-MMU-9851347 https://reactome.org/PathwayBrowser/#/R-MMU-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9853499 https://reactome.org/PathwayBrowser/#/R-MMU-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9854415 https://reactome.org/PathwayBrowser/#/R-MMU-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9856871 https://reactome.org/PathwayBrowser/#/R-MMU-9856871 MDH1 reduces OA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9858321 https://reactome.org/PathwayBrowser/#/R-MMU-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9858589 https://reactome.org/PathwayBrowser/#/R-MMU-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9858590 https://reactome.org/PathwayBrowser/#/R-MMU-9858590 DLST transfers glutaryl to CoA IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9859148 https://reactome.org/PathwayBrowser/#/R-MMU-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9859172 https://reactome.org/PathwayBrowser/#/R-MMU-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9861616 https://reactome.org/PathwayBrowser/#/R-MMU-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9861642 https://reactome.org/PathwayBrowser/#/R-MMU-9861642 NEK1 phosphorylates ME1 IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9861660 https://reactome.org/PathwayBrowser/#/R-MMU-9861660 ME1 tetramer decarboxylates OA to PYR IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9861734 https://reactome.org/PathwayBrowser/#/R-MMU-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9864415 https://reactome.org/PathwayBrowser/#/R-MMU-9864415 AAC1 imports a proton IEA Mus musculus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-MMU-9864415 https://reactome.org/PathwayBrowser/#/R-MMU-9864415 AAC1 imports a proton IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9909159 https://reactome.org/PathwayBrowser/#/R-MMU-9909159 HK1 phosphorylates Mannose to Man6P IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9915971 https://reactome.org/PathwayBrowser/#/R-MMU-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9915993 https://reactome.org/PathwayBrowser/#/R-MMU-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9915997 https://reactome.org/PathwayBrowser/#/R-MMU-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Mus musculus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-MMU-9929439 https://reactome.org/PathwayBrowser/#/R-MMU-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9931940 https://reactome.org/PathwayBrowser/#/R-MMU-9931940 Akr1b1 reduces galactose to galactitol TAS Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9935449 https://reactome.org/PathwayBrowser/#/R-MMU-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Mus musculus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-MMU-9935469 https://reactome.org/PathwayBrowser/#/R-MMU-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MMU-9937295 https://reactome.org/PathwayBrowser/#/R-MMU-9937295 SRD5A3 reduces polyprenal to dolichal IEA Mus musculus 15378 R-ALL-70106 H+ [cytosol] R-MTU-868622 https://reactome.org/PathwayBrowser/#/R-MTU-868622 Glucose is transferred from UDP-glucose onto glucose-6-phosphate TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-879245 https://reactome.org/PathwayBrowser/#/R-MTU-879245 mycothiol binds formaldehyde and is dehydrogenated TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-879266 https://reactome.org/PathwayBrowser/#/R-MTU-879266 mycothiol is oxidized to mycothione TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-879293 https://reactome.org/PathwayBrowser/#/R-MTU-879293 formylmycothiol hydrolyzes into mycothiol and formate TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-879322 https://reactome.org/PathwayBrowser/#/R-MTU-879322 mycothione is reduced to mycothiol TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-936583 https://reactome.org/PathwayBrowser/#/R-MTU-936583 APS is phosphorylated to PAPS TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-936655 https://reactome.org/PathwayBrowser/#/R-MTU-936655 sulfite results from reduction of APS TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-936703 https://reactome.org/PathwayBrowser/#/R-MTU-936703 sulfite is reduced to sulfide TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-9635428 https://reactome.org/PathwayBrowser/#/R-MTU-9635428 FadD26, FadD28 transfer LCFA adenylate ester to Pks5 TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-9635452 https://reactome.org/PathwayBrowser/#/R-MTU-9635452 Pks5 transforms LFCA adenylate ester to mycocerosyl TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-9635480 https://reactome.org/PathwayBrowser/#/R-MTU-9635480 FadD26, FadD28 transfer adenylyl group to a LCFA TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-964842 https://reactome.org/PathwayBrowser/#/R-MTU-964842 Shikimate results from hydration of DHS TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-MTU-964914 https://reactome.org/PathwayBrowser/#/R-MTU-964914 DHQ from DAHP dephosphorylation TAS Mycobacterium tuberculosis 15378 R-ALL-70106 H+ [cytosol] R-OCU-2161568 https://reactome.org/PathwayBrowser/#/R-OCU-2161568 PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD TAS Oryctolagus cuniculus 15378 R-ALL-70106 H+ [cytosol] R-PFA-111215 https://reactome.org/PathwayBrowser/#/R-PFA-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-111524 https://reactome.org/PathwayBrowser/#/R-PFA-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1222516 https://reactome.org/PathwayBrowser/#/R-PFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Plasmodium falciparum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-PFA-1222516 https://reactome.org/PathwayBrowser/#/R-PFA-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1475022 https://reactome.org/PathwayBrowser/#/R-PFA-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1475026 https://reactome.org/PathwayBrowser/#/R-PFA-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-1475028 https://reactome.org/PathwayBrowser/#/R-PFA-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-1475032 https://reactome.org/PathwayBrowser/#/R-PFA-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1475435 https://reactome.org/PathwayBrowser/#/R-PFA-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1475436 https://reactome.org/PathwayBrowser/#/R-PFA-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-1606273 https://reactome.org/PathwayBrowser/#/R-PFA-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Plasmodium falciparum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-189425 https://reactome.org/PathwayBrowser/#/R-PFA-189425 UROD decarboxylates URO3 to COPRO3 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-189439 https://reactome.org/PathwayBrowser/#/R-PFA-189439 ALAD condenses 2 dALAs to form PBG IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-189442 https://reactome.org/PathwayBrowser/#/R-PFA-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-189465 https://reactome.org/PathwayBrowser/#/R-PFA-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-190182 https://reactome.org/PathwayBrowser/#/R-PFA-190182 UROD decarboxylates URO1 to COPRO1 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-193064 https://reactome.org/PathwayBrowser/#/R-PFA-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-196753 https://reactome.org/PathwayBrowser/#/R-PFA-196753 2xPPCS ligates PPanK with Cys IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-196840 https://reactome.org/PathwayBrowser/#/R-PFA-196840 3xPPCDC:3FMN decarboxylates PPC IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-196929 https://reactome.org/PathwayBrowser/#/R-PFA-196929 FLAD1 phosphorylates FMN IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-196964 https://reactome.org/PathwayBrowser/#/R-PFA-196964 RFK:Mg2+ phosphorylates RIB IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-197271 https://reactome.org/PathwayBrowser/#/R-PFA-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-200555 https://reactome.org/PathwayBrowser/#/R-PFA-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-200644 https://reactome.org/PathwayBrowser/#/R-PFA-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-200718 https://reactome.org/PathwayBrowser/#/R-PFA-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-202111 https://reactome.org/PathwayBrowser/#/R-PFA-202111 AKT1 phosphorylates eNOS IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-204617 https://reactome.org/PathwayBrowser/#/R-PFA-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-204647 https://reactome.org/PathwayBrowser/#/R-PFA-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-2395512 https://reactome.org/PathwayBrowser/#/R-PFA-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-2395517 https://reactome.org/PathwayBrowser/#/R-PFA-2395517 NADPH transfers electrons to FDXR IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2395818 https://reactome.org/PathwayBrowser/#/R-PFA-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2395849 https://reactome.org/PathwayBrowser/#/R-PFA-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2395872 https://reactome.org/PathwayBrowser/#/R-PFA-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2509827 https://reactome.org/PathwayBrowser/#/R-PFA-2509827 ITPA hydrolyses ITP to IMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2509831 https://reactome.org/PathwayBrowser/#/R-PFA-2509831 ITPA hydrolyses XTP to XMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-2509838 https://reactome.org/PathwayBrowser/#/R-PFA-2509838 ITPA hydrolyses dITP to dIMP IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-3323079 https://reactome.org/PathwayBrowser/#/R-PFA-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-418365 https://reactome.org/PathwayBrowser/#/R-PFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Plasmodium falciparum 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-PFA-418365 https://reactome.org/PathwayBrowser/#/R-PFA-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-426043 https://reactome.org/PathwayBrowser/#/R-PFA-426043 2-AG hydrolysis to arachidonate by MAGL IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-427910 https://reactome.org/PathwayBrowser/#/R-PFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Plasmodium falciparum 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-PFA-427910 https://reactome.org/PathwayBrowser/#/R-PFA-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-428123 https://reactome.org/PathwayBrowser/#/R-PFA-428123 KDSR reduces 3-ketosphingoid IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-428185 https://reactome.org/PathwayBrowser/#/R-PFA-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-429157 https://reactome.org/PathwayBrowser/#/R-PFA-429157 ABCC4 accumulation of dense granule contents IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-429714 https://reactome.org/PathwayBrowser/#/R-PFA-429714 CSNK1G2 phosphorylates p-CERT1-2 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-434650 https://reactome.org/PathwayBrowser/#/R-PFA-434650 MATEs mediate extrusion of xenobiotics IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-PFA-435171 https://reactome.org/PathwayBrowser/#/R-PFA-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-435349 https://reactome.org/PathwayBrowser/#/R-PFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-435349 https://reactome.org/PathwayBrowser/#/R-PFA-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-PFA-450971 https://reactome.org/PathwayBrowser/#/R-PFA-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-504054 https://reactome.org/PathwayBrowser/#/R-PFA-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-5263614 https://reactome.org/PathwayBrowser/#/R-PFA-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-5263616 https://reactome.org/PathwayBrowser/#/R-PFA-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-548800 https://reactome.org/PathwayBrowser/#/R-PFA-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-548814 https://reactome.org/PathwayBrowser/#/R-PFA-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-548818 https://reactome.org/PathwayBrowser/#/R-PFA-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-548831 https://reactome.org/PathwayBrowser/#/R-PFA-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Plasmodium falciparum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-PFA-5623643 https://reactome.org/PathwayBrowser/#/R-PFA-5623643 RDH13 reduces atRAL to atROL IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-5694018 https://reactome.org/PathwayBrowser/#/R-PFA-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-597628 https://reactome.org/PathwayBrowser/#/R-PFA-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6783221 https://reactome.org/PathwayBrowser/#/R-PFA-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6783939 https://reactome.org/PathwayBrowser/#/R-PFA-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6783955 https://reactome.org/PathwayBrowser/#/R-PFA-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6787642 https://reactome.org/PathwayBrowser/#/R-PFA-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6798335 https://reactome.org/PathwayBrowser/#/R-PFA-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-6801342 https://reactome.org/PathwayBrowser/#/R-PFA-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-6806967 https://reactome.org/PathwayBrowser/#/R-PFA-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-70377 https://reactome.org/PathwayBrowser/#/R-PFA-70377 G6PD multimers dehydrogenate G6P IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-70420 https://reactome.org/PathwayBrowser/#/R-PFA-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-70449 https://reactome.org/PathwayBrowser/#/R-PFA-70449 GADPH tetramer dehydrogenates GA3P IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-70482 https://reactome.org/PathwayBrowser/#/R-PFA-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-70599 https://reactome.org/PathwayBrowser/#/R-PFA-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-70664 https://reactome.org/PathwayBrowser/#/R-PFA-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-70881 https://reactome.org/PathwayBrowser/#/R-PFA-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-70975 https://reactome.org/PathwayBrowser/#/R-PFA-70975 CS acetylates OA to citrate IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-70979 https://reactome.org/PathwayBrowser/#/R-PFA-70979 MDH2 dimer dehydrogenates MAL IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-71401 https://reactome.org/PathwayBrowser/#/R-PFA-71401 OGDH dimer decarboxylates 2-OG IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-71670 https://reactome.org/PathwayBrowser/#/R-PFA-71670 PKM dephosphorylates PEP to PYR IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-71682 https://reactome.org/PathwayBrowser/#/R-PFA-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73571 https://reactome.org/PathwayBrowser/#/R-PFA-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73573 https://reactome.org/PathwayBrowser/#/R-PFA-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73577 https://reactome.org/PathwayBrowser/#/R-PFA-73577 CAD hexamer transforms L-Gln to CAP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73580 https://reactome.org/PathwayBrowser/#/R-PFA-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73646 https://reactome.org/PathwayBrowser/#/R-PFA-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73647 https://reactome.org/PathwayBrowser/#/R-PFA-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Plasmodium falciparum 15378 R-ALL-9668967 H+ [nucleoplasm] R-PFA-73666 https://reactome.org/PathwayBrowser/#/R-PFA-73666 dUTP + H2O => dUMP + pyrophosphate IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73792 https://reactome.org/PathwayBrowser/#/R-PFA-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-73794 https://reactome.org/PathwayBrowser/#/R-PFA-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-74723 https://reactome.org/PathwayBrowser/#/R-PFA-74723 Endosome acidification IEA Plasmodium falciparum 15378 R-ALL-74722 H+ [endosome lumen] R-PFA-74723 https://reactome.org/PathwayBrowser/#/R-PFA-74723 Endosome acidification IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-75851 https://reactome.org/PathwayBrowser/#/R-PFA-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-75889 https://reactome.org/PathwayBrowser/#/R-PFA-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8850846 https://reactome.org/PathwayBrowser/#/R-PFA-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8850854 https://reactome.org/PathwayBrowser/#/R-PFA-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851089 https://reactome.org/PathwayBrowser/#/R-PFA-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851110 https://reactome.org/PathwayBrowser/#/R-PFA-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851129 https://reactome.org/PathwayBrowser/#/R-PFA-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851356 https://reactome.org/PathwayBrowser/#/R-PFA-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851396 https://reactome.org/PathwayBrowser/#/R-PFA-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851538 https://reactome.org/PathwayBrowser/#/R-PFA-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Plasmodium falciparum 15378 R-ALL-351626 H+ [extracellular region] R-PFA-8851550 https://reactome.org/PathwayBrowser/#/R-PFA-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-8862152 https://reactome.org/PathwayBrowser/#/R-PFA-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Plasmodium falciparum 15378 R-ALL-9668967 H+ [nucleoplasm] R-PFA-8866601 https://reactome.org/PathwayBrowser/#/R-PFA-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-8876789 https://reactome.org/PathwayBrowser/#/R-PFA-8876789 CARNMT1 methylates CARN to Anserine IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-8876889 https://reactome.org/PathwayBrowser/#/R-PFA-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-8954468 https://reactome.org/PathwayBrowser/#/R-PFA-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-8955030 https://reactome.org/PathwayBrowser/#/R-PFA-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-8955760 https://reactome.org/PathwayBrowser/#/R-PFA-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-8959510 https://reactome.org/PathwayBrowser/#/R-PFA-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Plasmodium falciparum 15378 R-ALL-193465 H+ [peroxisomal matrix] R-PFA-9013198 https://reactome.org/PathwayBrowser/#/R-PFA-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 15378 R-ALL-74722 H+ [endosome lumen] R-PFA-917841 https://reactome.org/PathwayBrowser/#/R-PFA-917841 Acidification of Tf:TfR1 containing endosome IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-917979 https://reactome.org/PathwayBrowser/#/R-PFA-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9705714 https://reactome.org/PathwayBrowser/#/R-PFA-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9731228 https://reactome.org/PathwayBrowser/#/R-PFA-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9731590 https://reactome.org/PathwayBrowser/#/R-PFA-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9731613 https://reactome.org/PathwayBrowser/#/R-PFA-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9731632 https://reactome.org/PathwayBrowser/#/R-PFA-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9748945 https://reactome.org/PathwayBrowser/#/R-PFA-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9748957 https://reactome.org/PathwayBrowser/#/R-PFA-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9837337 https://reactome.org/PathwayBrowser/#/R-PFA-9837337 DCAKD phosphorylates DP-CoA IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9843721 https://reactome.org/PathwayBrowser/#/R-PFA-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-9853499 https://reactome.org/PathwayBrowser/#/R-PFA-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-9854415 https://reactome.org/PathwayBrowser/#/R-PFA-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-9859148 https://reactome.org/PathwayBrowser/#/R-PFA-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-9859172 https://reactome.org/PathwayBrowser/#/R-PFA-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-PFA-9864415 https://reactome.org/PathwayBrowser/#/R-PFA-9864415 AAC1 imports a proton IEA Plasmodium falciparum 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-PFA-9864415 https://reactome.org/PathwayBrowser/#/R-PFA-9864415 AAC1 imports a proton IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9909159 https://reactome.org/PathwayBrowser/#/R-PFA-9909159 HK1 phosphorylates Mannose to Man6P IEA Plasmodium falciparum 15378 R-ALL-70106 H+ [cytosol] R-PFA-9937295 https://reactome.org/PathwayBrowser/#/R-PFA-9937295 SRD5A3 reduces polyprenal to dolichal IEA Plasmodium falciparum 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-109343 https://reactome.org/PathwayBrowser/#/R-RNO-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-111215 https://reactome.org/PathwayBrowser/#/R-RNO-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-111524 https://reactome.org/PathwayBrowser/#/R-RNO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-111883 https://reactome.org/PathwayBrowser/#/R-RNO-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1222516 https://reactome.org/PathwayBrowser/#/R-RNO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-1222516 https://reactome.org/PathwayBrowser/#/R-RNO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Rattus norvegicus 15378 R-ALL-2000349 H+ [phagolysosome] R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1237045 https://reactome.org/PathwayBrowser/#/R-RNO-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1237047 https://reactome.org/PathwayBrowser/#/R-RNO-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1237059 https://reactome.org/PathwayBrowser/#/R-RNO-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1237081 https://reactome.org/PathwayBrowser/#/R-RNO-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1475017 https://reactome.org/PathwayBrowser/#/R-RNO-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1475022 https://reactome.org/PathwayBrowser/#/R-RNO-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-1475025 https://reactome.org/PathwayBrowser/#/R-RNO-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1475026 https://reactome.org/PathwayBrowser/#/R-RNO-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-1475028 https://reactome.org/PathwayBrowser/#/R-RNO-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-1475032 https://reactome.org/PathwayBrowser/#/R-RNO-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1475435 https://reactome.org/PathwayBrowser/#/R-RNO-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1475436 https://reactome.org/PathwayBrowser/#/R-RNO-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1497869 https://reactome.org/PathwayBrowser/#/R-RNO-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-158609 https://reactome.org/PathwayBrowser/#/R-RNO-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-159790 https://reactome.org/PathwayBrowser/#/R-RNO-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-1605797 https://reactome.org/PathwayBrowser/#/R-RNO-1605797 SMPD1 hydrolyzes SPHM IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1606273 https://reactome.org/PathwayBrowser/#/R-RNO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1606288 https://reactome.org/PathwayBrowser/#/R-RNO-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-1606807 https://reactome.org/PathwayBrowser/#/R-RNO-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-1614362 https://reactome.org/PathwayBrowser/#/R-RNO-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1614567 https://reactome.org/PathwayBrowser/#/R-RNO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1614591 https://reactome.org/PathwayBrowser/#/R-RNO-1614591 Excess cysteine yields lanthionine and H2S IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1614614 https://reactome.org/PathwayBrowser/#/R-RNO-1614614 Cysteine is degraded to pyruvate and H2S IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1614631 https://reactome.org/PathwayBrowser/#/R-RNO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-162730 https://reactome.org/PathwayBrowser/#/R-RNO-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-163120 https://reactome.org/PathwayBrowser/#/R-RNO-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-163217 https://reactome.org/PathwayBrowser/#/R-RNO-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-1638104 https://reactome.org/PathwayBrowser/#/R-RNO-1638104 UGCG transfers glucose to ceramide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1638845 https://reactome.org/PathwayBrowser/#/R-RNO-1638845 CERK phosphorylates CERA to form C1P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1640164 https://reactome.org/PathwayBrowser/#/R-RNO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-164651 https://reactome.org/PathwayBrowser/#/R-RNO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-164834 https://reactome.org/PathwayBrowser/#/R-RNO-164834 Enzyme-bound ATP is released IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-164834 https://reactome.org/PathwayBrowser/#/R-RNO-164834 Enzyme-bound ATP is released IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-1655879 https://reactome.org/PathwayBrowser/#/R-RNO-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Rattus norvegicus 15378 R-ALL-9631150 H+ [endolysosome lumen] R-RNO-1678920 https://reactome.org/PathwayBrowser/#/R-RNO-1678920 TLR processing at low pH IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-169270 https://reactome.org/PathwayBrowser/#/R-RNO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 UCP1 imports a proton IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-170026 https://reactome.org/PathwayBrowser/#/R-RNO-170026 UCP1 imports a proton IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-173597 https://reactome.org/PathwayBrowser/#/R-RNO-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-174389 https://reactome.org/PathwayBrowser/#/R-RNO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-174392 https://reactome.org/PathwayBrowser/#/R-RNO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-174438 https://reactome.org/PathwayBrowser/#/R-RNO-174438 Formation of the Flap Intermediate on the C-strand IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-189425 https://reactome.org/PathwayBrowser/#/R-RNO-189425 UROD decarboxylates URO3 to COPRO3 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-189439 https://reactome.org/PathwayBrowser/#/R-RNO-189439 ALAD condenses 2 dALAs to form PBG IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-189442 https://reactome.org/PathwayBrowser/#/R-RNO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-189465 https://reactome.org/PathwayBrowser/#/R-RNO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-190182 https://reactome.org/PathwayBrowser/#/R-RNO-190182 UROD decarboxylates URO1 to COPRO1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191323 https://reactome.org/PathwayBrowser/#/R-RNO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191352 https://reactome.org/PathwayBrowser/#/R-RNO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191402 https://reactome.org/PathwayBrowser/#/R-RNO-191402 Reduction of presqualene diphosphate to form squalene IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192033 https://reactome.org/PathwayBrowser/#/R-RNO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192036 https://reactome.org/PathwayBrowser/#/R-RNO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-192042 https://reactome.org/PathwayBrowser/#/R-RNO-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192067 https://reactome.org/PathwayBrowser/#/R-RNO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192097 https://reactome.org/PathwayBrowser/#/R-RNO-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192160 https://reactome.org/PathwayBrowser/#/R-RNO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193064 https://reactome.org/PathwayBrowser/#/R-RNO-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193073 https://reactome.org/PathwayBrowser/#/R-RNO-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-193455 https://reactome.org/PathwayBrowser/#/R-RNO-193455 (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193497 https://reactome.org/PathwayBrowser/#/R-RNO-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-193508 https://reactome.org/PathwayBrowser/#/R-RNO-193508 (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193746 https://reactome.org/PathwayBrowser/#/R-RNO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193755 https://reactome.org/PathwayBrowser/#/R-RNO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193758 https://reactome.org/PathwayBrowser/#/R-RNO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193781 https://reactome.org/PathwayBrowser/#/R-RNO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193789 https://reactome.org/PathwayBrowser/#/R-RNO-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193800 https://reactome.org/PathwayBrowser/#/R-RNO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193816 https://reactome.org/PathwayBrowser/#/R-RNO-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193821 https://reactome.org/PathwayBrowser/#/R-RNO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193824 https://reactome.org/PathwayBrowser/#/R-RNO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193841 https://reactome.org/PathwayBrowser/#/R-RNO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194023 https://reactome.org/PathwayBrowser/#/R-RNO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194632 https://reactome.org/PathwayBrowser/#/R-RNO-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194642 https://reactome.org/PathwayBrowser/#/R-RNO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-ALL-194688 H+ [nuclear envelope] R-RNO-194674 https://reactome.org/PathwayBrowser/#/R-RNO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194689 https://reactome.org/PathwayBrowser/#/R-RNO-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194698 https://reactome.org/PathwayBrowser/#/R-RNO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-194718 https://reactome.org/PathwayBrowser/#/R-RNO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196060 https://reactome.org/PathwayBrowser/#/R-RNO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196350 https://reactome.org/PathwayBrowser/#/R-RNO-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196372 https://reactome.org/PathwayBrowser/#/R-RNO-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196402 https://reactome.org/PathwayBrowser/#/R-RNO-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196417 https://reactome.org/PathwayBrowser/#/R-RNO-196417 Reduction of desmosterol to cholesterol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196753 https://reactome.org/PathwayBrowser/#/R-RNO-196753 2xPPCS ligates PPanK with Cys IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196754 https://reactome.org/PathwayBrowser/#/R-RNO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196773 https://reactome.org/PathwayBrowser/#/R-RNO-196773 COASY phosphorylates DP-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196840 https://reactome.org/PathwayBrowser/#/R-RNO-196840 3xPPCDC:3FMN decarboxylates PPC IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196857 https://reactome.org/PathwayBrowser/#/R-RNO-196857 PANK2 phosphorylates PanK IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196929 https://reactome.org/PathwayBrowser/#/R-RNO-196929 FLAD1 phosphorylates FMN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196955 https://reactome.org/PathwayBrowser/#/R-RNO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-196964 https://reactome.org/PathwayBrowser/#/R-RNO-196964 RFK:Mg2+ phosphorylates RIB IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197198 https://reactome.org/PathwayBrowser/#/R-RNO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197235 https://reactome.org/PathwayBrowser/#/R-RNO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197250 https://reactome.org/PathwayBrowser/#/R-RNO-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197268 https://reactome.org/PathwayBrowser/#/R-RNO-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197271 https://reactome.org/PathwayBrowser/#/R-RNO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197963 https://reactome.org/PathwayBrowser/#/R-RNO-197963 DHFR2 reduces FOLA to DHF IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-197972 https://reactome.org/PathwayBrowser/#/R-RNO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-198824 https://reactome.org/PathwayBrowser/#/R-RNO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-199203 https://reactome.org/PathwayBrowser/#/R-RNO-199203 PANK1/3 phosphorylate PanK IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200423 https://reactome.org/PathwayBrowser/#/R-RNO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-200474 https://reactome.org/PathwayBrowser/#/R-RNO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-200512 https://reactome.org/PathwayBrowser/#/R-RNO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200555 https://reactome.org/PathwayBrowser/#/R-RNO-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200644 https://reactome.org/PathwayBrowser/#/R-RNO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200646 https://reactome.org/PathwayBrowser/#/R-RNO-200646 Cytosolic folate export across the plasma membrane IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-200646 https://reactome.org/PathwayBrowser/#/R-RNO-200646 Cytosolic folate export across the plasma membrane IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200676 https://reactome.org/PathwayBrowser/#/R-RNO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200718 https://reactome.org/PathwayBrowser/#/R-RNO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-200729 https://reactome.org/PathwayBrowser/#/R-RNO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-200729 https://reactome.org/PathwayBrowser/#/R-RNO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-202111 https://reactome.org/PathwayBrowser/#/R-RNO-202111 AKT1 phosphorylates eNOS IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-203613 https://reactome.org/PathwayBrowser/#/R-RNO-203613 Depalmitoylation of eNOS IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-203946 https://reactome.org/PathwayBrowser/#/R-RNO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-204617 https://reactome.org/PathwayBrowser/#/R-RNO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-204647 https://reactome.org/PathwayBrowser/#/R-RNO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209772 https://reactome.org/PathwayBrowser/#/R-RNO-209772 Thyroxine is deiodinated to triiodothyronine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209821 https://reactome.org/PathwayBrowser/#/R-RNO-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-209903 https://reactome.org/PathwayBrowser/#/R-RNO-209903 Noradrenaline is converted to adrenaline IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-209973 https://reactome.org/PathwayBrowser/#/R-RNO-209973 Tyrosine is diiodinated IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-210404 https://reactome.org/PathwayBrowser/#/R-RNO-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161549 https://reactome.org/PathwayBrowser/#/R-RNO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161614 https://reactome.org/PathwayBrowser/#/R-RNO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161651 https://reactome.org/PathwayBrowser/#/R-RNO-2161651 PGE2 is converted to PGF2a by CBR1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161779 https://reactome.org/PathwayBrowser/#/R-RNO-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2162078 https://reactome.org/PathwayBrowser/#/R-RNO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162186 https://reactome.org/PathwayBrowser/#/R-RNO-2162186 COQ3 methylates DeMQ10H2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162187 https://reactome.org/PathwayBrowser/#/R-RNO-2162187 COQ6 hydroxylates DHB IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162188 https://reactome.org/PathwayBrowser/#/R-RNO-2162188 COQ5 methylates MDMQ10H2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162193 https://reactome.org/PathwayBrowser/#/R-RNO-2162193 COQ3 methylates DHDB IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2162195 https://reactome.org/PathwayBrowser/#/R-RNO-2162195 COQ4 decarboxylates MHDB IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2395512 https://reactome.org/PathwayBrowser/#/R-RNO-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-2395517 https://reactome.org/PathwayBrowser/#/R-RNO-2395517 NADPH transfers electrons to FDXR IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395818 https://reactome.org/PathwayBrowser/#/R-RNO-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395849 https://reactome.org/PathwayBrowser/#/R-RNO-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395869 https://reactome.org/PathwayBrowser/#/R-RNO-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395872 https://reactome.org/PathwayBrowser/#/R-RNO-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395873 https://reactome.org/PathwayBrowser/#/R-RNO-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395876 https://reactome.org/PathwayBrowser/#/R-RNO-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395879 https://reactome.org/PathwayBrowser/#/R-RNO-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2395965 https://reactome.org/PathwayBrowser/#/R-RNO-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2408514 https://reactome.org/PathwayBrowser/#/R-RNO-2408514 GSSeSG is reduced to GSSeH and GSH by Gsr TAS Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2408524 https://reactome.org/PathwayBrowser/#/R-RNO-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2408553 https://reactome.org/PathwayBrowser/#/R-RNO-2408553 SeO3(2-) combines with GSH to form GSSeSG and GSSG TAS Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2453833 https://reactome.org/PathwayBrowser/#/R-RNO-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2464822 https://reactome.org/PathwayBrowser/#/R-RNO-2464822 RDH12 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2465940 https://reactome.org/PathwayBrowser/#/R-RNO-2465940 atRAL is reduced to atROL IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-2509793 https://reactome.org/PathwayBrowser/#/R-RNO-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-2509816 https://reactome.org/PathwayBrowser/#/R-RNO-2509816 NUDT16 hydrolyses IDP to IMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2509827 https://reactome.org/PathwayBrowser/#/R-RNO-2509827 ITPA hydrolyses ITP to IMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2509831 https://reactome.org/PathwayBrowser/#/R-RNO-2509831 ITPA hydrolyses XTP to XMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2509838 https://reactome.org/PathwayBrowser/#/R-RNO-2509838 ITPA hydrolyses dITP to dIMP IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-2534378 https://reactome.org/PathwayBrowser/#/R-RNO-2534378 Hv1 Mediated H+ Permeability IEA Rattus norvegicus 15378 R-ALL-1132304 H+ [cytoplasm] R-RNO-2534378 https://reactome.org/PathwayBrowser/#/R-RNO-2534378 Hv1 Mediated H+ Permeability IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-RNO-264615 https://reactome.org/PathwayBrowser/#/R-RNO-264615 Loading of acetylcholine in synaptic vesicles IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-266070 https://reactome.org/PathwayBrowser/#/R-RNO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-2671885 https://reactome.org/PathwayBrowser/#/R-RNO-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2730692 https://reactome.org/PathwayBrowser/#/R-RNO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Rattus norvegicus 15378 R-ALL-74722 H+ [endosome lumen] R-RNO-2730692 https://reactome.org/PathwayBrowser/#/R-RNO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2730959 https://reactome.org/PathwayBrowser/#/R-RNO-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-2730959 https://reactome.org/PathwayBrowser/#/R-RNO-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-2855252 https://reactome.org/PathwayBrowser/#/R-RNO-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3095889 https://reactome.org/PathwayBrowser/#/R-RNO-3095889 MMACHC dealkylates RCbl IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3149518 https://reactome.org/PathwayBrowser/#/R-RNO-3149518 MTRR reduces cob(II)alamin to meCbl IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3149519 https://reactome.org/PathwayBrowser/#/R-RNO-3149519 MMACHC decyanates CNCbl IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-3159253 https://reactome.org/PathwayBrowser/#/R-RNO-3159253 MMAB adenosylates cob(I)alamin IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3322001 https://reactome.org/PathwayBrowser/#/R-RNO-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3322003 https://reactome.org/PathwayBrowser/#/R-RNO-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3322025 https://reactome.org/PathwayBrowser/#/R-RNO-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3322041 https://reactome.org/PathwayBrowser/#/R-RNO-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-3323050 https://reactome.org/PathwayBrowser/#/R-RNO-3323050 TXNRD2 catalyzes the reduction of TXN2 by NADPH IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-3323079 https://reactome.org/PathwayBrowser/#/R-RNO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-350869 https://reactome.org/PathwayBrowser/#/R-RNO-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-350901 https://reactome.org/PathwayBrowser/#/R-RNO-350901 Iodide is organified IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-352174 https://reactome.org/PathwayBrowser/#/R-RNO-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-352182 https://reactome.org/PathwayBrowser/#/R-RNO-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-372347 https://reactome.org/PathwayBrowser/#/R-RNO-372347 Cytosolic PYR is transported to the mitochondrial matrix TAS Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-372448 https://reactome.org/PathwayBrowser/#/R-RNO-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-373867 https://reactome.org/PathwayBrowser/#/R-RNO-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-373875 https://reactome.org/PathwayBrowser/#/R-RNO-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-375405 https://reactome.org/PathwayBrowser/#/R-RNO-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-375405 https://reactome.org/PathwayBrowser/#/R-RNO-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-375417 https://reactome.org/PathwayBrowser/#/R-RNO-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-3781024 https://reactome.org/PathwayBrowser/#/R-RNO-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-379048 https://reactome.org/PathwayBrowser/#/R-RNO-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-380608 https://reactome.org/PathwayBrowser/#/R-RNO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-389540 https://reactome.org/PathwayBrowser/#/R-RNO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-389550 https://reactome.org/PathwayBrowser/#/R-RNO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-389609 https://reactome.org/PathwayBrowser/#/R-RNO-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-389826 https://reactome.org/PathwayBrowser/#/R-RNO-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-389995 https://reactome.org/PathwayBrowser/#/R-RNO-389995 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-390251 https://reactome.org/PathwayBrowser/#/R-RNO-390251 HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-390304 https://reactome.org/PathwayBrowser/#/R-RNO-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-390393 https://reactome.org/PathwayBrowser/#/R-RNO-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-390425 https://reactome.org/PathwayBrowser/#/R-RNO-390425 FAR1 reduces PalmCoA to HXOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-390438 https://reactome.org/PathwayBrowser/#/R-RNO-390438 FAR2 reduces PalmCoA to HXOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-418365 https://reactome.org/PathwayBrowser/#/R-RNO-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Rattus norvegicus 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-RNO-418365 https://reactome.org/PathwayBrowser/#/R-RNO-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-425577 https://reactome.org/PathwayBrowser/#/R-RNO-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-425965 https://reactome.org/PathwayBrowser/#/R-RNO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Rattus norvegicus 15378 R-ALL-425999 H+ [late endosome lumen] R-RNO-425965 https://reactome.org/PathwayBrowser/#/R-RNO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-425983 https://reactome.org/PathwayBrowser/#/R-RNO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Rattus norvegicus 15378 R-ALL-425978 H+ [early endosome lumen] R-RNO-425983 https://reactome.org/PathwayBrowser/#/R-RNO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-425994 https://reactome.org/PathwayBrowser/#/R-RNO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-425994 https://reactome.org/PathwayBrowser/#/R-RNO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-426015 https://reactome.org/PathwayBrowser/#/R-RNO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-426015 https://reactome.org/PathwayBrowser/#/R-RNO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-426043 https://reactome.org/PathwayBrowser/#/R-RNO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-427555 https://reactome.org/PathwayBrowser/#/R-RNO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-427555 https://reactome.org/PathwayBrowser/#/R-RNO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-427910 https://reactome.org/PathwayBrowser/#/R-RNO-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-427910 https://reactome.org/PathwayBrowser/#/R-RNO-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-427998 https://reactome.org/PathwayBrowser/#/R-RNO-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-428007 https://reactome.org/PathwayBrowser/#/R-RNO-428007 Proton-coupled histidine and di-peptide cotransport IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-428015 https://reactome.org/PathwayBrowser/#/R-RNO-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428052 https://reactome.org/PathwayBrowser/#/R-RNO-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Rattus norvegicus 15378 R-ALL-428548 H+ [synaptic vesicle] R-RNO-428052 https://reactome.org/PathwayBrowser/#/R-RNO-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428123 https://reactome.org/PathwayBrowser/#/R-RNO-428123 KDSR reduces 3-ketosphingoid IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428127 https://reactome.org/PathwayBrowser/#/R-RNO-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428185 https://reactome.org/PathwayBrowser/#/R-RNO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428273 https://reactome.org/PathwayBrowser/#/R-RNO-428273 SPHK1 phosphorylates sphingoid IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-428625 https://reactome.org/PathwayBrowser/#/R-RNO-428625 Vesicular inhibitory amino acid transport IEA Rattus norvegicus 15378 R-ALL-428548 H+ [synaptic vesicle] R-RNO-428625 https://reactome.org/PathwayBrowser/#/R-RNO-428625 Vesicular inhibitory amino acid transport IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-429016 https://reactome.org/PathwayBrowser/#/R-RNO-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-429101 https://reactome.org/PathwayBrowser/#/R-RNO-429101 HMIT co-transports myo-inositol with a proton IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-429101 https://reactome.org/PathwayBrowser/#/R-RNO-429101 HMIT co-transports myo-inositol with a proton IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-429157 https://reactome.org/PathwayBrowser/#/R-RNO-429157 ABCC4 accumulation of dense granule contents IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-433698 https://reactome.org/PathwayBrowser/#/R-RNO-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-434650 https://reactome.org/PathwayBrowser/#/R-RNO-434650 MATEs mediate extrusion of xenobiotics IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-435171 https://reactome.org/PathwayBrowser/#/R-RNO-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-435349 https://reactome.org/PathwayBrowser/#/R-RNO-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-435349 https://reactome.org/PathwayBrowser/#/R-RNO-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-444393 https://reactome.org/PathwayBrowser/#/R-RNO-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-444393 https://reactome.org/PathwayBrowser/#/R-RNO-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-444419 https://reactome.org/PathwayBrowser/#/R-RNO-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-444419 https://reactome.org/PathwayBrowser/#/R-RNO-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-444731 https://reactome.org/PathwayBrowser/#/R-RNO-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-446195 https://reactome.org/PathwayBrowser/#/R-RNO-446195 DOLK phosphorylates DCHOL to DOLP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-446200 https://reactome.org/PathwayBrowser/#/R-RNO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-446221 https://reactome.org/PathwayBrowser/#/R-RNO-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-446277 https://reactome.org/PathwayBrowser/#/R-RNO-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-446277 https://reactome.org/PathwayBrowser/#/R-RNO-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-446278 https://reactome.org/PathwayBrowser/#/R-RNO-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-446278 https://reactome.org/PathwayBrowser/#/R-RNO-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-450971 https://reactome.org/PathwayBrowser/#/R-RNO-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-469659 https://reactome.org/PathwayBrowser/#/R-RNO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-504054 https://reactome.org/PathwayBrowser/#/R-RNO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-508040 https://reactome.org/PathwayBrowser/#/R-RNO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-508308 https://reactome.org/PathwayBrowser/#/R-RNO-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-508369 https://reactome.org/PathwayBrowser/#/R-RNO-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-508473 https://reactome.org/PathwayBrowser/#/R-RNO-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-514604 https://reactome.org/PathwayBrowser/#/R-RNO-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5263614 https://reactome.org/PathwayBrowser/#/R-RNO-5263614 MeSeOH is reduced to MeSeH by TXNRD1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5263616 https://reactome.org/PathwayBrowser/#/R-RNO-5263616 MeSeO2H is reduced to MeSeOH by TXNRD1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5340130 https://reactome.org/PathwayBrowser/#/R-RNO-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-5340130 https://reactome.org/PathwayBrowser/#/R-RNO-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5362518 https://reactome.org/PathwayBrowser/#/R-RNO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5362522 https://reactome.org/PathwayBrowser/#/R-RNO-5362522 ALDHs oxidise atRAL to atRA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5362564 https://reactome.org/PathwayBrowser/#/R-RNO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5362721 https://reactome.org/PathwayBrowser/#/R-RNO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5419165 https://reactome.org/PathwayBrowser/#/R-RNO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5423637 https://reactome.org/PathwayBrowser/#/R-RNO-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-548800 https://reactome.org/PathwayBrowser/#/R-RNO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-548814 https://reactome.org/PathwayBrowser/#/R-RNO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-548815 https://reactome.org/PathwayBrowser/#/R-RNO-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-548818 https://reactome.org/PathwayBrowser/#/R-RNO-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-548831 https://reactome.org/PathwayBrowser/#/R-RNO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5615668 https://reactome.org/PathwayBrowser/#/R-RNO-5615668 AKR1C3 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-5623643 https://reactome.org/PathwayBrowser/#/R-RNO-5623643 RDH13 reduces atRAL to atROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5652172 https://reactome.org/PathwayBrowser/#/R-RNO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5652195 https://reactome.org/PathwayBrowser/#/R-RNO-5652195 SORD oxidizes D-sorbitol to Fru IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5661240 https://reactome.org/PathwayBrowser/#/R-RNO-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5661256 https://reactome.org/PathwayBrowser/#/R-RNO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5661290 https://reactome.org/PathwayBrowser/#/R-RNO-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5662471 https://reactome.org/PathwayBrowser/#/R-RNO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Rattus norvegicus 15378 R-ALL-5668577 H+ [melanosome lumen] R-RNO-5662662 https://reactome.org/PathwayBrowser/#/R-RNO-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-5690042 https://reactome.org/PathwayBrowser/#/R-RNO-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-5690046 https://reactome.org/PathwayBrowser/#/R-RNO-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Rattus norvegicus 15378 R-ALL-428040 H+ [lysosomal lumen] R-RNO-5690517 https://reactome.org/PathwayBrowser/#/R-RNO-5690517 PPT1 hydrolyses palmitoylated proteins IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5692237 https://reactome.org/PathwayBrowser/#/R-RNO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5692261 https://reactome.org/PathwayBrowser/#/R-RNO-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5692283 https://reactome.org/PathwayBrowser/#/R-RNO-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5693148 https://reactome.org/PathwayBrowser/#/R-RNO-5693148 BCKDK phosphorylates BCKDH IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-5693347 https://reactome.org/PathwayBrowser/#/R-RNO-5693347 CRYM reduces P2C to PPCA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5693390 https://reactome.org/PathwayBrowser/#/R-RNO-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-5693691 https://reactome.org/PathwayBrowser/#/R-RNO-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5693967 https://reactome.org/PathwayBrowser/#/R-RNO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5694018 https://reactome.org/PathwayBrowser/#/R-RNO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5694462 https://reactome.org/PathwayBrowser/#/R-RNO-5694462 ABHD6,12 hydrolyse 3AG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5696021 https://reactome.org/PathwayBrowser/#/R-RNO-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5696080 https://reactome.org/PathwayBrowser/#/R-RNO-5696080 ALDH3B1 oxidises HXAL to PALM IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5696091 https://reactome.org/PathwayBrowser/#/R-RNO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5696101 https://reactome.org/PathwayBrowser/#/R-RNO-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5696457 https://reactome.org/PathwayBrowser/#/R-RNO-5696457 BDH2 dehydrogenates 3HBA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-5696822 https://reactome.org/PathwayBrowser/#/R-RNO-5696822 AKR1B15 reduces EST17b to E1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-5696838 https://reactome.org/PathwayBrowser/#/R-RNO-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-597628 https://reactome.org/PathwayBrowser/#/R-RNO-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6783221 https://reactome.org/PathwayBrowser/#/R-RNO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6783939 https://reactome.org/PathwayBrowser/#/R-RNO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6783955 https://reactome.org/PathwayBrowser/#/R-RNO-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6784224 https://reactome.org/PathwayBrowser/#/R-RNO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6784402 https://reactome.org/PathwayBrowser/#/R-RNO-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-6785933 https://reactome.org/PathwayBrowser/#/R-RNO-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6786245 https://reactome.org/PathwayBrowser/#/R-RNO-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6786720 https://reactome.org/PathwayBrowser/#/R-RNO-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6787642 https://reactome.org/PathwayBrowser/#/R-RNO-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6787757 https://reactome.org/PathwayBrowser/#/R-RNO-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6788611 https://reactome.org/PathwayBrowser/#/R-RNO-6788611 HYKK phosphorylates 5HLYS IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6788999 https://reactome.org/PathwayBrowser/#/R-RNO-6788999 HV1-mediated H+ transfer IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-6788999 https://reactome.org/PathwayBrowser/#/R-RNO-6788999 HV1-mediated H+ transfer IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-6789031 https://reactome.org/PathwayBrowser/#/R-RNO-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-6789126 https://reactome.org/PathwayBrowser/#/R-RNO-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6793590 https://reactome.org/PathwayBrowser/#/R-RNO-6793590 LIPT2 transfers octanoyl group to GCSH IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6793591 https://reactome.org/PathwayBrowser/#/R-RNO-6793591 LIAS synthesizes lipoyl-GCSH IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6798317 https://reactome.org/PathwayBrowser/#/R-RNO-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6798335 https://reactome.org/PathwayBrowser/#/R-RNO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6799495 https://reactome.org/PathwayBrowser/#/R-RNO-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6801342 https://reactome.org/PathwayBrowser/#/R-RNO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6803771 https://reactome.org/PathwayBrowser/#/R-RNO-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-6806647 https://reactome.org/PathwayBrowser/#/R-RNO-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6806831 https://reactome.org/PathwayBrowser/#/R-RNO-6806831 CYB5Rs reduce MetHb to HbA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6806967 https://reactome.org/PathwayBrowser/#/R-RNO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6807055 https://reactome.org/PathwayBrowser/#/R-RNO-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6807064 https://reactome.org/PathwayBrowser/#/R-RNO-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6807826 https://reactome.org/PathwayBrowser/#/R-RNO-6807826 LDHAL6B reduces PYR to LACT IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6808464 https://reactome.org/PathwayBrowser/#/R-RNO-6808464 ALDH3B2 oxidises HXAL to PALM IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-6808487 https://reactome.org/PathwayBrowser/#/R-RNO-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6808496 https://reactome.org/PathwayBrowser/#/R-RNO-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6809264 https://reactome.org/PathwayBrowser/#/R-RNO-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6809287 https://reactome.org/PathwayBrowser/#/R-RNO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6809810 https://reactome.org/PathwayBrowser/#/R-RNO-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-6810474 https://reactome.org/PathwayBrowser/#/R-RNO-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6810594 https://reactome.org/PathwayBrowser/#/R-RNO-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6813749 https://reactome.org/PathwayBrowser/#/R-RNO-6813749 ALDH1A1 oxidises GA to DGA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-6814165 https://reactome.org/PathwayBrowser/#/R-RNO-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70286 https://reactome.org/PathwayBrowser/#/R-RNO-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70333 https://reactome.org/PathwayBrowser/#/R-RNO-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70355 https://reactome.org/PathwayBrowser/#/R-RNO-70355 GALK1 phosphorylates Gal to Gal1P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70377 https://reactome.org/PathwayBrowser/#/R-RNO-70377 G6PD multimers dehydrogenate G6P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70420 https://reactome.org/PathwayBrowser/#/R-RNO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70449 https://reactome.org/PathwayBrowser/#/R-RNO-70449 GADPH tetramer dehydrogenates GA3P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70467 https://reactome.org/PathwayBrowser/#/R-RNO-70467 PFK tetramer phosphorylates Fru(6)P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70482 https://reactome.org/PathwayBrowser/#/R-RNO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70501 https://reactome.org/PathwayBrowser/#/R-RNO-70501 PC carboxylates PYR to OA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70510 https://reactome.org/PathwayBrowser/#/R-RNO-70510 LDH tetramer oxidises LACT to PYR IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70589 https://reactome.org/PathwayBrowser/#/R-RNO-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70599 https://reactome.org/PathwayBrowser/#/R-RNO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70600 https://reactome.org/PathwayBrowser/#/R-RNO-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-70606 https://reactome.org/PathwayBrowser/#/R-RNO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70664 https://reactome.org/PathwayBrowser/#/R-RNO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70670 https://reactome.org/PathwayBrowser/#/R-RNO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70679 https://reactome.org/PathwayBrowser/#/R-RNO-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70745 https://reactome.org/PathwayBrowser/#/R-RNO-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70773 https://reactome.org/PathwayBrowser/#/R-RNO-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70800 https://reactome.org/PathwayBrowser/#/R-RNO-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70837 https://reactome.org/PathwayBrowser/#/R-RNO-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70859 https://reactome.org/PathwayBrowser/#/R-RNO-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70881 https://reactome.org/PathwayBrowser/#/R-RNO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70885 https://reactome.org/PathwayBrowser/#/R-RNO-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70893 https://reactome.org/PathwayBrowser/#/R-RNO-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70938 https://reactome.org/PathwayBrowser/#/R-RNO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70940 https://reactome.org/PathwayBrowser/#/R-RNO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70941 https://reactome.org/PathwayBrowser/#/R-RNO-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70975 https://reactome.org/PathwayBrowser/#/R-RNO-70975 CS acetylates OA to citrate IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-70979 https://reactome.org/PathwayBrowser/#/R-RNO-70979 MDH2 dimer dehydrogenates MAL IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-71046 https://reactome.org/PathwayBrowser/#/R-RNO-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71130 https://reactome.org/PathwayBrowser/#/R-RNO-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71181 https://reactome.org/PathwayBrowser/#/R-RNO-71181 FAH cleaves 4FAA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71217 https://reactome.org/PathwayBrowser/#/R-RNO-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71260 https://reactome.org/PathwayBrowser/#/R-RNO-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71286 https://reactome.org/PathwayBrowser/#/R-RNO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71296 https://reactome.org/PathwayBrowser/#/R-RNO-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-71401 https://reactome.org/PathwayBrowser/#/R-RNO-71401 OGDH dimer decarboxylates 2-OG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71541 https://reactome.org/PathwayBrowser/#/R-RNO-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71588 https://reactome.org/PathwayBrowser/#/R-RNO-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71670 https://reactome.org/PathwayBrowser/#/R-RNO-71670 PKM dephosphorylates PEP to PYR IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71682 https://reactome.org/PathwayBrowser/#/R-RNO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71691 https://reactome.org/PathwayBrowser/#/R-RNO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71707 https://reactome.org/PathwayBrowser/#/R-RNO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-71723 https://reactome.org/PathwayBrowser/#/R-RNO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71802 https://reactome.org/PathwayBrowser/#/R-RNO-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-71849 https://reactome.org/PathwayBrowser/#/R-RNO-71849 LDH tetramer reduces PYR to LACT IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73564 https://reactome.org/PathwayBrowser/#/R-RNO-73564 UMPS dimer decarboxylates OMP to UMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73571 https://reactome.org/PathwayBrowser/#/R-RNO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73573 https://reactome.org/PathwayBrowser/#/R-RNO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73577 https://reactome.org/PathwayBrowser/#/R-RNO-73577 CAD hexamer transforms L-Gln to CAP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73580 https://reactome.org/PathwayBrowser/#/R-RNO-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73585 https://reactome.org/PathwayBrowser/#/R-RNO-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73589 https://reactome.org/PathwayBrowser/#/R-RNO-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73591 https://reactome.org/PathwayBrowser/#/R-RNO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73596 https://reactome.org/PathwayBrowser/#/R-RNO-73596 dCMP + H2O => dUMP + NH4+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73616 https://reactome.org/PathwayBrowser/#/R-RNO-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73618 https://reactome.org/PathwayBrowser/#/R-RNO-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73620 https://reactome.org/PathwayBrowser/#/R-RNO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73646 https://reactome.org/PathwayBrowser/#/R-RNO-73646 thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73647 https://reactome.org/PathwayBrowser/#/R-RNO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-73666 https://reactome.org/PathwayBrowser/#/R-RNO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73792 https://reactome.org/PathwayBrowser/#/R-RNO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73794 https://reactome.org/PathwayBrowser/#/R-RNO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73805 https://reactome.org/PathwayBrowser/#/R-RNO-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73806 https://reactome.org/PathwayBrowser/#/R-RNO-73806 AIR + CO2 => CAIR IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73810 https://reactome.org/PathwayBrowser/#/R-RNO-73810 FGAM + ATP => AIR + ADP + Pi IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73812 https://reactome.org/PathwayBrowser/#/R-RNO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73813 https://reactome.org/PathwayBrowser/#/R-RNO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-73814 https://reactome.org/PathwayBrowser/#/R-RNO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-73912 https://reactome.org/PathwayBrowser/#/R-RNO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-73920 https://reactome.org/PathwayBrowser/#/R-RNO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-74255 https://reactome.org/PathwayBrowser/#/R-RNO-74255 Guanine + H2O => Xanthine + NH4+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-74723 https://reactome.org/PathwayBrowser/#/R-RNO-74723 Endosome acidification IEA Rattus norvegicus 15378 R-ALL-74722 H+ [endosome lumen] R-RNO-74723 https://reactome.org/PathwayBrowser/#/R-RNO-74723 Endosome acidification IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-74872 https://reactome.org/PathwayBrowser/#/R-RNO-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-75851 https://reactome.org/PathwayBrowser/#/R-RNO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-75872 https://reactome.org/PathwayBrowser/#/R-RNO-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-75883 https://reactome.org/PathwayBrowser/#/R-RNO-75883 DHRS7B reduces GO3P to HXDG3P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-75889 https://reactome.org/PathwayBrowser/#/R-RNO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76354 https://reactome.org/PathwayBrowser/#/R-RNO-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76373 https://reactome.org/PathwayBrowser/#/R-RNO-76373 N-hydroxylation of 4-aminobiphenyl IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76386 https://reactome.org/PathwayBrowser/#/R-RNO-76386 CYP1A2 S-demethylates 6MMP IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76416 https://reactome.org/PathwayBrowser/#/R-RNO-76416 Benzene is hydroxylated to phenol IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76426 https://reactome.org/PathwayBrowser/#/R-RNO-76426 N-atom dealkylation of caffeine IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76453 https://reactome.org/PathwayBrowser/#/R-RNO-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76456 https://reactome.org/PathwayBrowser/#/R-RNO-76456 O-atom dealkylation of dextromethorphan IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76466 https://reactome.org/PathwayBrowser/#/R-RNO-76466 CYP4A11 12-hydroxylates DDCX IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76472 https://reactome.org/PathwayBrowser/#/R-RNO-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-76475 https://reactome.org/PathwayBrowser/#/R-RNO-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77254 https://reactome.org/PathwayBrowser/#/R-RNO-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77283 https://reactome.org/PathwayBrowser/#/R-RNO-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77303 https://reactome.org/PathwayBrowser/#/R-RNO-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77312 https://reactome.org/PathwayBrowser/#/R-RNO-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77323 https://reactome.org/PathwayBrowser/#/R-RNO-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77331 https://reactome.org/PathwayBrowser/#/R-RNO-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-77342 https://reactome.org/PathwayBrowser/#/R-RNO-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-804969 https://reactome.org/PathwayBrowser/#/R-RNO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8849638 https://reactome.org/PathwayBrowser/#/R-RNO-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8850846 https://reactome.org/PathwayBrowser/#/R-RNO-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8850854 https://reactome.org/PathwayBrowser/#/R-RNO-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851089 https://reactome.org/PathwayBrowser/#/R-RNO-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851110 https://reactome.org/PathwayBrowser/#/R-RNO-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851129 https://reactome.org/PathwayBrowser/#/R-RNO-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-8851225 https://reactome.org/PathwayBrowser/#/R-RNO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-8851234 https://reactome.org/PathwayBrowser/#/R-RNO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851356 https://reactome.org/PathwayBrowser/#/R-RNO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851396 https://reactome.org/PathwayBrowser/#/R-RNO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-RNO-8851494 https://reactome.org/PathwayBrowser/#/R-RNO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851538 https://reactome.org/PathwayBrowser/#/R-RNO-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8851550 https://reactome.org/PathwayBrowser/#/R-RNO-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-8856223 https://reactome.org/PathwayBrowser/#/R-RNO-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8862137 https://reactome.org/PathwayBrowser/#/R-RNO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-8862152 https://reactome.org/PathwayBrowser/#/R-RNO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8863494 https://reactome.org/PathwayBrowser/#/R-RNO-8863494 ASICs bind STOML3, (STOM) IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-8863761 https://reactome.org/PathwayBrowser/#/R-RNO-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-8866601 https://reactome.org/PathwayBrowser/#/R-RNO-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8869606 https://reactome.org/PathwayBrowser/#/R-RNO-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8869633 https://reactome.org/PathwayBrowser/#/R-RNO-8869633 NMRK1 phosphorylates NR to yield NMN IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8870346 https://reactome.org/PathwayBrowser/#/R-RNO-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8875623 https://reactome.org/PathwayBrowser/#/R-RNO-8875623 SLC25A18,22 import L-Glu, H+ IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-8875623 https://reactome.org/PathwayBrowser/#/R-RNO-8875623 SLC25A18,22 import L-Glu, H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8876789 https://reactome.org/PathwayBrowser/#/R-RNO-8876789 CARNMT1 methylates CARN to Anserine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8876889 https://reactome.org/PathwayBrowser/#/R-RNO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-8878914 https://reactome.org/PathwayBrowser/#/R-RNO-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-888548 https://reactome.org/PathwayBrowser/#/R-RNO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-888572 https://reactome.org/PathwayBrowser/#/R-RNO-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-888577 https://reactome.org/PathwayBrowser/#/R-RNO-888577 Synthesis of GABA by GAD2 IEA Rattus norvegicus 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-RNO-8933635 https://reactome.org/PathwayBrowser/#/R-RNO-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8936442 https://reactome.org/PathwayBrowser/#/R-RNO-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8938076 https://reactome.org/PathwayBrowser/#/R-RNO-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8939959 https://reactome.org/PathwayBrowser/#/R-RNO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8940070 https://reactome.org/PathwayBrowser/#/R-RNO-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8942575 https://reactome.org/PathwayBrowser/#/R-RNO-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-8952873 https://reactome.org/PathwayBrowser/#/R-RNO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-8954468 https://reactome.org/PathwayBrowser/#/R-RNO-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-8955030 https://reactome.org/PathwayBrowser/#/R-RNO-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8955760 https://reactome.org/PathwayBrowser/#/R-RNO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8955844 https://reactome.org/PathwayBrowser/#/R-RNO-8955844 RBKS phosphorylates ribose to R5P IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-8956458 https://reactome.org/PathwayBrowser/#/R-RNO-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8959510 https://reactome.org/PathwayBrowser/#/R-RNO-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-8959719 https://reactome.org/PathwayBrowser/#/R-RNO-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9009950 https://reactome.org/PathwayBrowser/#/R-RNO-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9011595 https://reactome.org/PathwayBrowser/#/R-RNO-9011595 GSTZ1 dimer dehalogenates DCA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9012016 https://reactome.org/PathwayBrowser/#/R-RNO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9012036 https://reactome.org/PathwayBrowser/#/R-RNO-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-9013198 https://reactome.org/PathwayBrowser/#/R-RNO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9024766 https://reactome.org/PathwayBrowser/#/R-RNO-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9027043 https://reactome.org/PathwayBrowser/#/R-RNO-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9027302 https://reactome.org/PathwayBrowser/#/R-RNO-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9027321 https://reactome.org/PathwayBrowser/#/R-RNO-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9037761 https://reactome.org/PathwayBrowser/#/R-RNO-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Rattus norvegicus 15378 R-ALL-74722 H+ [endosome lumen] R-RNO-917811 https://reactome.org/PathwayBrowser/#/R-RNO-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 15378 R-ALL-74722 H+ [endosome lumen] R-RNO-917841 https://reactome.org/PathwayBrowser/#/R-RNO-917841 Acidification of Tf:TfR1 containing endosome IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-917891 https://reactome.org/PathwayBrowser/#/R-RNO-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-917933 https://reactome.org/PathwayBrowser/#/R-RNO-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-917979 https://reactome.org/PathwayBrowser/#/R-RNO-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-937311 https://reactome.org/PathwayBrowser/#/R-RNO-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9619024 https://reactome.org/PathwayBrowser/#/R-RNO-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-9645220 https://reactome.org/PathwayBrowser/#/R-RNO-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-9650165 https://reactome.org/PathwayBrowser/#/R-RNO-9650165 ASIC trimers bind H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9695949 https://reactome.org/PathwayBrowser/#/R-RNO-9695949 SPHK2 phosphorylates sphingoid IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9705713 https://reactome.org/PathwayBrowser/#/R-RNO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9705714 https://reactome.org/PathwayBrowser/#/R-RNO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9709098 https://reactome.org/PathwayBrowser/#/R-RNO-9709098 DHFR dimer reduces FOLA to DHF IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-9727198 https://reactome.org/PathwayBrowser/#/R-RNO-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9727347 https://reactome.org/PathwayBrowser/#/R-RNO-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9727349 https://reactome.org/PathwayBrowser/#/R-RNO-9727349 XDH dehydrogenates xanthine to form urate IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9731228 https://reactome.org/PathwayBrowser/#/R-RNO-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9731590 https://reactome.org/PathwayBrowser/#/R-RNO-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9731613 https://reactome.org/PathwayBrowser/#/R-RNO-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9731632 https://reactome.org/PathwayBrowser/#/R-RNO-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9748945 https://reactome.org/PathwayBrowser/#/R-RNO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9748957 https://reactome.org/PathwayBrowser/#/R-RNO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9748979 https://reactome.org/PathwayBrowser/#/R-RNO-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9748983 https://reactome.org/PathwayBrowser/#/R-RNO-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9748991 https://reactome.org/PathwayBrowser/#/R-RNO-9748991 XDH oxidises 6MP to 6TU IEA Rattus norvegicus 15378 R-ALL-351626 H+ [extracellular region] R-RNO-9749609 https://reactome.org/PathwayBrowser/#/R-RNO-9749609 BCHE hydrolyzes ASA- IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9749647 https://reactome.org/PathwayBrowser/#/R-RNO-9749647 CES2 hydrolyzes ASA- IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9749792 https://reactome.org/PathwayBrowser/#/R-RNO-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9753285 https://reactome.org/PathwayBrowser/#/R-RNO-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9755937 https://reactome.org/PathwayBrowser/#/R-RNO-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756134 https://reactome.org/PathwayBrowser/#/R-RNO-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756138 https://reactome.org/PathwayBrowser/#/R-RNO-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756156 https://reactome.org/PathwayBrowser/#/R-RNO-9756156 UGT1A3 lactonizes ATV to ATVL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756162 https://reactome.org/PathwayBrowser/#/R-RNO-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756169 https://reactome.org/PathwayBrowser/#/R-RNO-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756177 https://reactome.org/PathwayBrowser/#/R-RNO-9756177 PON1,3 hydrolyse ATVL to ATV IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756180 https://reactome.org/PathwayBrowser/#/R-RNO-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9756183 https://reactome.org/PathwayBrowser/#/R-RNO-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-975629 https://reactome.org/PathwayBrowser/#/R-RNO-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9757706 https://reactome.org/PathwayBrowser/#/R-RNO-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9758661 https://reactome.org/PathwayBrowser/#/R-RNO-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9758674 https://reactome.org/PathwayBrowser/#/R-RNO-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9758682 https://reactome.org/PathwayBrowser/#/R-RNO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9759259 https://reactome.org/PathwayBrowser/#/R-RNO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9759549 https://reactome.org/PathwayBrowser/#/R-RNO-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9760094 https://reactome.org/PathwayBrowser/#/R-RNO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-977301 https://reactome.org/PathwayBrowser/#/R-RNO-977301 Histidine is decarboxylated to histamine IEA Rattus norvegicus 15378 R-ALL-193465 H+ [peroxisomal matrix] R-RNO-977317 https://reactome.org/PathwayBrowser/#/R-RNO-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-977348 https://reactome.org/PathwayBrowser/#/R-RNO-977348 PHGDH tetramer dehydrogenates 3PG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9773976 https://reactome.org/PathwayBrowser/#/R-RNO-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9794270 https://reactome.org/PathwayBrowser/#/R-RNO-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Rattus norvegicus 15378 R-ALL-9668967 H+ [nucleoplasm] R-RNO-9825790 https://reactome.org/PathwayBrowser/#/R-RNO-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9837337 https://reactome.org/PathwayBrowser/#/R-RNO-9837337 DCAKD phosphorylates DP-CoA IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9843721 https://reactome.org/PathwayBrowser/#/R-RNO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9844587 https://reactome.org/PathwayBrowser/#/R-RNO-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9844860 https://reactome.org/PathwayBrowser/#/R-RNO-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9845516 https://reactome.org/PathwayBrowser/#/R-RNO-9845516 B3GALT4 transfers Gal to gangliosides IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9845538 https://reactome.org/PathwayBrowser/#/R-RNO-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9845587 https://reactome.org/PathwayBrowser/#/R-RNO-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9846305 https://reactome.org/PathwayBrowser/#/R-RNO-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9846332 https://reactome.org/PathwayBrowser/#/R-RNO-9846332 FUT1,2 transfer fucose to gangliosides IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9846477 https://reactome.org/PathwayBrowser/#/R-RNO-9846477 A4GALT transfers galactose to LacCer IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9846501 https://reactome.org/PathwayBrowser/#/R-RNO-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Rattus norvegicus 15378 R-ALL-425969 H+ [Golgi lumen] R-RNO-9851347 https://reactome.org/PathwayBrowser/#/R-RNO-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9853499 https://reactome.org/PathwayBrowser/#/R-RNO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9854415 https://reactome.org/PathwayBrowser/#/R-RNO-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9856871 https://reactome.org/PathwayBrowser/#/R-RNO-9856871 MDH1 reduces OA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9858321 https://reactome.org/PathwayBrowser/#/R-RNO-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9858589 https://reactome.org/PathwayBrowser/#/R-RNO-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9858590 https://reactome.org/PathwayBrowser/#/R-RNO-9858590 DLST transfers glutaryl to CoA IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9859148 https://reactome.org/PathwayBrowser/#/R-RNO-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9859172 https://reactome.org/PathwayBrowser/#/R-RNO-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9861616 https://reactome.org/PathwayBrowser/#/R-RNO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9861642 https://reactome.org/PathwayBrowser/#/R-RNO-9861642 NEK1 phosphorylates ME1 IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9861660 https://reactome.org/PathwayBrowser/#/R-RNO-9861660 ME1 tetramer decarboxylates OA to PYR IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9861734 https://reactome.org/PathwayBrowser/#/R-RNO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9864415 https://reactome.org/PathwayBrowser/#/R-RNO-9864415 AAC1 imports a proton IEA Rattus norvegicus 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-RNO-9864415 https://reactome.org/PathwayBrowser/#/R-RNO-9864415 AAC1 imports a proton IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9909159 https://reactome.org/PathwayBrowser/#/R-RNO-9909159 HK1 phosphorylates Mannose to Man6P IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9915971 https://reactome.org/PathwayBrowser/#/R-RNO-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9915992 https://reactome.org/PathwayBrowser/#/R-RNO-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9915993 https://reactome.org/PathwayBrowser/#/R-RNO-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9915997 https://reactome.org/PathwayBrowser/#/R-RNO-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Rattus norvegicus 15378 R-ALL-113529 H+ [mitochondrial matrix] R-RNO-9929439 https://reactome.org/PathwayBrowser/#/R-RNO-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9935449 https://reactome.org/PathwayBrowser/#/R-RNO-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Rattus norvegicus 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-RNO-9935469 https://reactome.org/PathwayBrowser/#/R-RNO-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9937295 https://reactome.org/PathwayBrowser/#/R-RNO-9937295 SRD5A3 reduces polyprenal to dolichal IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9937298 https://reactome.org/PathwayBrowser/#/R-RNO-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-RNO-9937340 https://reactome.org/PathwayBrowser/#/R-RNO-9937340 DHRSX reduces dolichal to dolichol IEA Rattus norvegicus 15378 R-ALL-70106 H+ [cytosol] R-SCE-111215 https://reactome.org/PathwayBrowser/#/R-SCE-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-111524 https://reactome.org/PathwayBrowser/#/R-SCE-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-111883 https://reactome.org/PathwayBrowser/#/R-SCE-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1222516 https://reactome.org/PathwayBrowser/#/R-SCE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Saccharomyces cerevisiae 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SCE-1222516 https://reactome.org/PathwayBrowser/#/R-SCE-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1237119 https://reactome.org/PathwayBrowser/#/R-SCE-1237119 Acireductone is oxidized to MOB IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1497810 https://reactome.org/PathwayBrowser/#/R-SCE-1497810 Uncoupled eNOS favours the formation of superoxide IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1606273 https://reactome.org/PathwayBrowser/#/R-SCE-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1614567 https://reactome.org/PathwayBrowser/#/R-SCE-1614567 Excess homocysteine yields homolanthionine and H2S IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1614591 https://reactome.org/PathwayBrowser/#/R-SCE-1614591 Excess cysteine yields lanthionine and H2S IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1614614 https://reactome.org/PathwayBrowser/#/R-SCE-1614614 Cysteine is degraded to pyruvate and H2S IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1614631 https://reactome.org/PathwayBrowser/#/R-SCE-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-1640164 https://reactome.org/PathwayBrowser/#/R-SCE-1640164 ENPP7 hydrolyzes sphingomyelin IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SCE-164651 https://reactome.org/PathwayBrowser/#/R-SCE-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-169270 https://reactome.org/PathwayBrowser/#/R-SCE-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-174389 https://reactome.org/PathwayBrowser/#/R-SCE-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-174392 https://reactome.org/PathwayBrowser/#/R-SCE-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Saccharomyces cerevisiae 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SCE-189421 https://reactome.org/PathwayBrowser/#/R-SCE-189421 CPO transforms COPRO3 to PPGEN9 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-189425 https://reactome.org/PathwayBrowser/#/R-SCE-189425 UROD decarboxylates URO3 to COPRO3 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-189439 https://reactome.org/PathwayBrowser/#/R-SCE-189439 ALAD condenses 2 dALAs to form PBG IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-189442 https://reactome.org/PathwayBrowser/#/R-SCE-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-189465 https://reactome.org/PathwayBrowser/#/R-SCE-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-190182 https://reactome.org/PathwayBrowser/#/R-SCE-190182 UROD decarboxylates URO1 to COPRO1 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-191299 https://reactome.org/PathwayBrowser/#/R-SCE-191299 Squalene is oxidized to its epoxide IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-191323 https://reactome.org/PathwayBrowser/#/R-SCE-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-191352 https://reactome.org/PathwayBrowser/#/R-SCE-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-191402 https://reactome.org/PathwayBrowser/#/R-SCE-191402 Reduction of presqualene diphosphate to form squalene IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-191983 https://reactome.org/PathwayBrowser/#/R-SCE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-192033 https://reactome.org/PathwayBrowser/#/R-SCE-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-192036 https://reactome.org/PathwayBrowser/#/R-SCE-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-192067 https://reactome.org/PathwayBrowser/#/R-SCE-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-192160 https://reactome.org/PathwayBrowser/#/R-SCE-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193746 https://reactome.org/PathwayBrowser/#/R-SCE-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193755 https://reactome.org/PathwayBrowser/#/R-SCE-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193758 https://reactome.org/PathwayBrowser/#/R-SCE-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193781 https://reactome.org/PathwayBrowser/#/R-SCE-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193800 https://reactome.org/PathwayBrowser/#/R-SCE-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193821 https://reactome.org/PathwayBrowser/#/R-SCE-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193824 https://reactome.org/PathwayBrowser/#/R-SCE-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-193841 https://reactome.org/PathwayBrowser/#/R-SCE-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194641 https://reactome.org/PathwayBrowser/#/R-SCE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194642 https://reactome.org/PathwayBrowser/#/R-SCE-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194669 https://reactome.org/PathwayBrowser/#/R-SCE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-ALL-194688 H+ [nuclear envelope] R-SCE-194674 https://reactome.org/PathwayBrowser/#/R-SCE-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194678 https://reactome.org/PathwayBrowser/#/R-SCE-194678 CYP51A1 demethylates LNSOL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194698 https://reactome.org/PathwayBrowser/#/R-SCE-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-194718 https://reactome.org/PathwayBrowser/#/R-SCE-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-195664 https://reactome.org/PathwayBrowser/#/R-SCE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196060 https://reactome.org/PathwayBrowser/#/R-SCE-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196753 https://reactome.org/PathwayBrowser/#/R-SCE-196753 2xPPCS ligates PPanK with Cys IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196754 https://reactome.org/PathwayBrowser/#/R-SCE-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196773 https://reactome.org/PathwayBrowser/#/R-SCE-196773 COASY phosphorylates DP-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196840 https://reactome.org/PathwayBrowser/#/R-SCE-196840 3xPPCDC:3FMN decarboxylates PPC IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196929 https://reactome.org/PathwayBrowser/#/R-SCE-196929 FLAD1 phosphorylates FMN IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196955 https://reactome.org/PathwayBrowser/#/R-SCE-196955 2xENPP1 hydrolyzes FAD to FMN IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-196964 https://reactome.org/PathwayBrowser/#/R-SCE-196964 RFK:Mg2+ phosphorylates RIB IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197198 https://reactome.org/PathwayBrowser/#/R-SCE-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197235 https://reactome.org/PathwayBrowser/#/R-SCE-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197268 https://reactome.org/PathwayBrowser/#/R-SCE-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197271 https://reactome.org/PathwayBrowser/#/R-SCE-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197963 https://reactome.org/PathwayBrowser/#/R-SCE-197963 DHFR2 reduces FOLA to DHF IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-197972 https://reactome.org/PathwayBrowser/#/R-SCE-197972 DHF is reduced to tetrahydrofolate (THF) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-198824 https://reactome.org/PathwayBrowser/#/R-SCE-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200423 https://reactome.org/PathwayBrowser/#/R-SCE-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-200474 https://reactome.org/PathwayBrowser/#/R-SCE-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15378 R-ALL-9668967 H+ [nucleoplasm] R-SCE-200512 https://reactome.org/PathwayBrowser/#/R-SCE-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200555 https://reactome.org/PathwayBrowser/#/R-SCE-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200644 https://reactome.org/PathwayBrowser/#/R-SCE-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200646 https://reactome.org/PathwayBrowser/#/R-SCE-200646 Cytosolic folate export across the plasma membrane IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-200646 https://reactome.org/PathwayBrowser/#/R-SCE-200646 Cytosolic folate export across the plasma membrane IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200676 https://reactome.org/PathwayBrowser/#/R-SCE-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200718 https://reactome.org/PathwayBrowser/#/R-SCE-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-200729 https://reactome.org/PathwayBrowser/#/R-SCE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-200729 https://reactome.org/PathwayBrowser/#/R-SCE-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-202111 https://reactome.org/PathwayBrowser/#/R-SCE-202111 AKT1 phosphorylates eNOS IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-202127 https://reactome.org/PathwayBrowser/#/R-SCE-202127 eNOS synthesizes NO IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-203613 https://reactome.org/PathwayBrowser/#/R-SCE-203613 Depalmitoylation of eNOS IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-204617 https://reactome.org/PathwayBrowser/#/R-SCE-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-204647 https://reactome.org/PathwayBrowser/#/R-SCE-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-204662 https://reactome.org/PathwayBrowser/#/R-SCE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2161549 https://reactome.org/PathwayBrowser/#/R-SCE-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2161614 https://reactome.org/PathwayBrowser/#/R-SCE-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2162078 https://reactome.org/PathwayBrowser/#/R-SCE-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162186 https://reactome.org/PathwayBrowser/#/R-SCE-2162186 COQ3 methylates DeMQ10H2 IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162187 https://reactome.org/PathwayBrowser/#/R-SCE-2162187 COQ6 hydroxylates DHB IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162188 https://reactome.org/PathwayBrowser/#/R-SCE-2162188 COQ5 methylates MDMQ10H2 IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162193 https://reactome.org/PathwayBrowser/#/R-SCE-2162193 COQ3 methylates DHDB IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162194 https://reactome.org/PathwayBrowser/#/R-SCE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2162195 https://reactome.org/PathwayBrowser/#/R-SCE-2162195 COQ4 decarboxylates MHDB IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2164813 https://reactome.org/PathwayBrowser/#/R-SCE-2164813 HMPhOH is hydroxylated to MDMQ6H2 by HMPhOH monooxygenase TAS Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2395512 https://reactome.org/PathwayBrowser/#/R-SCE-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-2395517 https://reactome.org/PathwayBrowser/#/R-SCE-2395517 NADPH transfers electrons to FDXR IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2408518 https://reactome.org/PathwayBrowser/#/R-SCE-2408518 PAPSe is reduced to SeO3(2-) by MET16 TAS Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2465940 https://reactome.org/PathwayBrowser/#/R-SCE-2465940 atRAL is reduced to atROL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2509827 https://reactome.org/PathwayBrowser/#/R-SCE-2509827 ITPA hydrolyses ITP to IMP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2509831 https://reactome.org/PathwayBrowser/#/R-SCE-2509831 ITPA hydrolyses XTP to XMP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2509838 https://reactome.org/PathwayBrowser/#/R-SCE-2509838 ITPA hydrolyses dITP to dIMP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2564819 https://reactome.org/PathwayBrowser/#/R-SCE-2564819 NADPH reduces TAH18:DRE2 TAS Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-266070 https://reactome.org/PathwayBrowser/#/R-SCE-266070 LTC4 is exported from the cytosol by ABCC1 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-2730692 https://reactome.org/PathwayBrowser/#/R-SCE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Saccharomyces cerevisiae 15378 R-ALL-74722 H+ [endosome lumen] R-SCE-2730692 https://reactome.org/PathwayBrowser/#/R-SCE-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-3299680 https://reactome.org/PathwayBrowser/#/R-SCE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-3299682 https://reactome.org/PathwayBrowser/#/R-SCE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3299691 https://reactome.org/PathwayBrowser/#/R-SCE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322001 https://reactome.org/PathwayBrowser/#/R-SCE-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322003 https://reactome.org/PathwayBrowser/#/R-SCE-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322009 https://reactome.org/PathwayBrowser/#/R-SCE-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322014 https://reactome.org/PathwayBrowser/#/R-SCE-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322019 https://reactome.org/PathwayBrowser/#/R-SCE-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322025 https://reactome.org/PathwayBrowser/#/R-SCE-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3322041 https://reactome.org/PathwayBrowser/#/R-SCE-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-3323079 https://reactome.org/PathwayBrowser/#/R-SCE-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-352174 https://reactome.org/PathwayBrowser/#/R-SCE-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-352182 https://reactome.org/PathwayBrowser/#/R-SCE-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-372448 https://reactome.org/PathwayBrowser/#/R-SCE-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-375405 https://reactome.org/PathwayBrowser/#/R-SCE-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-375405 https://reactome.org/PathwayBrowser/#/R-SCE-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-375417 https://reactome.org/PathwayBrowser/#/R-SCE-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Saccharomyces cerevisiae 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SCE-3777112 https://reactome.org/PathwayBrowser/#/R-SCE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3780994 https://reactome.org/PathwayBrowser/#/R-SCE-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-3781024 https://reactome.org/PathwayBrowser/#/R-SCE-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-380608 https://reactome.org/PathwayBrowser/#/R-SCE-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-389540 https://reactome.org/PathwayBrowser/#/R-SCE-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-389550 https://reactome.org/PathwayBrowser/#/R-SCE-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-389609 https://reactome.org/PathwayBrowser/#/R-SCE-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-390304 https://reactome.org/PathwayBrowser/#/R-SCE-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-390393 https://reactome.org/PathwayBrowser/#/R-SCE-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-425965 https://reactome.org/PathwayBrowser/#/R-SCE-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Saccharomyces cerevisiae 15378 R-ALL-425999 H+ [late endosome lumen] R-SCE-425965 https://reactome.org/PathwayBrowser/#/R-SCE-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-425983 https://reactome.org/PathwayBrowser/#/R-SCE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Saccharomyces cerevisiae 15378 R-ALL-425978 H+ [early endosome lumen] R-SCE-425983 https://reactome.org/PathwayBrowser/#/R-SCE-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-425994 https://reactome.org/PathwayBrowser/#/R-SCE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-425994 https://reactome.org/PathwayBrowser/#/R-SCE-425994 Na+/H+ exchanger transport (at cell membrane) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-426015 https://reactome.org/PathwayBrowser/#/R-SCE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Saccharomyces cerevisiae 15378 R-ALL-425969 H+ [Golgi lumen] R-SCE-426015 https://reactome.org/PathwayBrowser/#/R-SCE-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-426043 https://reactome.org/PathwayBrowser/#/R-SCE-426043 2-AG hydrolysis to arachidonate by MAGL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-427555 https://reactome.org/PathwayBrowser/#/R-SCE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-427555 https://reactome.org/PathwayBrowser/#/R-SCE-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 15378 R-ALL-428040 H+ [lysosomal lumen] R-SCE-428007 https://reactome.org/PathwayBrowser/#/R-SCE-428007 Proton-coupled histidine and di-peptide cotransport IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-428123 https://reactome.org/PathwayBrowser/#/R-SCE-428123 KDSR reduces 3-ketosphingoid IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-428185 https://reactome.org/PathwayBrowser/#/R-SCE-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-428273 https://reactome.org/PathwayBrowser/#/R-SCE-428273 SPHK1 phosphorylates sphingoid IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-428625 https://reactome.org/PathwayBrowser/#/R-SCE-428625 Vesicular inhibitory amino acid transport IEA Saccharomyces cerevisiae 15378 R-ALL-428548 H+ [synaptic vesicle] R-SCE-428625 https://reactome.org/PathwayBrowser/#/R-SCE-428625 Vesicular inhibitory amino acid transport IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-429101 https://reactome.org/PathwayBrowser/#/R-SCE-429101 HMIT co-transports myo-inositol with a proton IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-429101 https://reactome.org/PathwayBrowser/#/R-SCE-429101 HMIT co-transports myo-inositol with a proton IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-434650 https://reactome.org/PathwayBrowser/#/R-SCE-434650 MATEs mediate extrusion of xenobiotics IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-446195 https://reactome.org/PathwayBrowser/#/R-SCE-446195 DOLK phosphorylates DCHOL to DOLP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-504054 https://reactome.org/PathwayBrowser/#/R-SCE-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-508040 https://reactome.org/PathwayBrowser/#/R-SCE-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5340130 https://reactome.org/PathwayBrowser/#/R-SCE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-428040 H+ [lysosomal lumen] R-SCE-5340130 https://reactome.org/PathwayBrowser/#/R-SCE-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5362518 https://reactome.org/PathwayBrowser/#/R-SCE-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5362522 https://reactome.org/PathwayBrowser/#/R-SCE-5362522 ALDHs oxidise atRAL to atRA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5362564 https://reactome.org/PathwayBrowser/#/R-SCE-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5419165 https://reactome.org/PathwayBrowser/#/R-SCE-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-548800 https://reactome.org/PathwayBrowser/#/R-SCE-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-548814 https://reactome.org/PathwayBrowser/#/R-SCE-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-548831 https://reactome.org/PathwayBrowser/#/R-SCE-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5615668 https://reactome.org/PathwayBrowser/#/R-SCE-5615668 AKR1C3 reduces atRAL to atROL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5652172 https://reactome.org/PathwayBrowser/#/R-SCE-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5652195 https://reactome.org/PathwayBrowser/#/R-SCE-5652195 SORD oxidizes D-sorbitol to Fru IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5661256 https://reactome.org/PathwayBrowser/#/R-SCE-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5662471 https://reactome.org/PathwayBrowser/#/R-SCE-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-5690042 https://reactome.org/PathwayBrowser/#/R-SCE-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5690565 https://reactome.org/PathwayBrowser/#/R-SCE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5692237 https://reactome.org/PathwayBrowser/#/R-SCE-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5692261 https://reactome.org/PathwayBrowser/#/R-SCE-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5692283 https://reactome.org/PathwayBrowser/#/R-SCE-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-5693347 https://reactome.org/PathwayBrowser/#/R-SCE-5693347 CRYM reduces P2C to PPCA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5693390 https://reactome.org/PathwayBrowser/#/R-SCE-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-5693681 https://reactome.org/PathwayBrowser/#/R-SCE-5693681 DUOX1,2 reduce O2 to H2O2 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5693761 https://reactome.org/PathwayBrowser/#/R-SCE-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-5693967 https://reactome.org/PathwayBrowser/#/R-SCE-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-5694018 https://reactome.org/PathwayBrowser/#/R-SCE-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5694462 https://reactome.org/PathwayBrowser/#/R-SCE-5694462 ABHD6,12 hydrolyse 3AG IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-5696080 https://reactome.org/PathwayBrowser/#/R-SCE-5696080 ALDH3B1 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-5696091 https://reactome.org/PathwayBrowser/#/R-SCE-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-5696822 https://reactome.org/PathwayBrowser/#/R-SCE-5696822 AKR1B15 reduces EST17b to E1 IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6783221 https://reactome.org/PathwayBrowser/#/R-SCE-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6783939 https://reactome.org/PathwayBrowser/#/R-SCE-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6783955 https://reactome.org/PathwayBrowser/#/R-SCE-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-6784224 https://reactome.org/PathwayBrowser/#/R-SCE-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-6786720 https://reactome.org/PathwayBrowser/#/R-SCE-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-6793590 https://reactome.org/PathwayBrowser/#/R-SCE-6793590 LIPT2 transfers octanoyl group to GCSH IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6801342 https://reactome.org/PathwayBrowser/#/R-SCE-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-6806967 https://reactome.org/PathwayBrowser/#/R-SCE-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6807053 https://reactome.org/PathwayBrowser/#/R-SCE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6807557 https://reactome.org/PathwayBrowser/#/R-SCE-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6808464 https://reactome.org/PathwayBrowser/#/R-SCE-6808464 ALDH3B2 oxidises HXAL to PALM IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-6809287 https://reactome.org/PathwayBrowser/#/R-SCE-6809287 NUDT12 hydrolyses NADH to NMNH IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-6813749 https://reactome.org/PathwayBrowser/#/R-SCE-6813749 ALDH1A1 oxidises GA to DGA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70286 https://reactome.org/PathwayBrowser/#/R-SCE-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70377 https://reactome.org/PathwayBrowser/#/R-SCE-70377 G6PD multimers dehydrogenate G6P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70420 https://reactome.org/PathwayBrowser/#/R-SCE-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70449 https://reactome.org/PathwayBrowser/#/R-SCE-70449 GADPH tetramer dehydrogenates GA3P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70467 https://reactome.org/PathwayBrowser/#/R-SCE-70467 PFK tetramer phosphorylates Fru(6)P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70482 https://reactome.org/PathwayBrowser/#/R-SCE-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70501 https://reactome.org/PathwayBrowser/#/R-SCE-70501 PC carboxylates PYR to OA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70599 https://reactome.org/PathwayBrowser/#/R-SCE-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-70606 https://reactome.org/PathwayBrowser/#/R-SCE-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70664 https://reactome.org/PathwayBrowser/#/R-SCE-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70670 https://reactome.org/PathwayBrowser/#/R-SCE-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70881 https://reactome.org/PathwayBrowser/#/R-SCE-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70938 https://reactome.org/PathwayBrowser/#/R-SCE-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70940 https://reactome.org/PathwayBrowser/#/R-SCE-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70975 https://reactome.org/PathwayBrowser/#/R-SCE-70975 CS acetylates OA to citrate IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-70979 https://reactome.org/PathwayBrowser/#/R-SCE-70979 MDH2 dimer dehydrogenates MAL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71200 https://reactome.org/PathwayBrowser/#/R-SCE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71217 https://reactome.org/PathwayBrowser/#/R-SCE-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71286 https://reactome.org/PathwayBrowser/#/R-SCE-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71296 https://reactome.org/PathwayBrowser/#/R-SCE-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-71401 https://reactome.org/PathwayBrowser/#/R-SCE-71401 OGDH dimer decarboxylates 2-OG IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71670 https://reactome.org/PathwayBrowser/#/R-SCE-71670 PKM dephosphorylates PEP to PYR IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71682 https://reactome.org/PathwayBrowser/#/R-SCE-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71691 https://reactome.org/PathwayBrowser/#/R-SCE-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71707 https://reactome.org/PathwayBrowser/#/R-SCE-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-71723 https://reactome.org/PathwayBrowser/#/R-SCE-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-71802 https://reactome.org/PathwayBrowser/#/R-SCE-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73571 https://reactome.org/PathwayBrowser/#/R-SCE-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73573 https://reactome.org/PathwayBrowser/#/R-SCE-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73577 https://reactome.org/PathwayBrowser/#/R-SCE-73577 CAD hexamer transforms L-Gln to CAP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73580 https://reactome.org/PathwayBrowser/#/R-SCE-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73647 https://reactome.org/PathwayBrowser/#/R-SCE-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Saccharomyces cerevisiae 15378 R-ALL-9668967 H+ [nucleoplasm] R-SCE-73666 https://reactome.org/PathwayBrowser/#/R-SCE-73666 dUTP + H2O => dUMP + pyrophosphate IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73792 https://reactome.org/PathwayBrowser/#/R-SCE-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73794 https://reactome.org/PathwayBrowser/#/R-SCE-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73810 https://reactome.org/PathwayBrowser/#/R-SCE-73810 FGAM + ATP => AIR + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73812 https://reactome.org/PathwayBrowser/#/R-SCE-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73813 https://reactome.org/PathwayBrowser/#/R-SCE-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-73814 https://reactome.org/PathwayBrowser/#/R-SCE-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-74255 https://reactome.org/PathwayBrowser/#/R-SCE-74255 Guanine + H2O => Xanthine + NH4+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-74723 https://reactome.org/PathwayBrowser/#/R-SCE-74723 Endosome acidification IEA Saccharomyces cerevisiae 15378 R-ALL-74722 H+ [endosome lumen] R-SCE-74723 https://reactome.org/PathwayBrowser/#/R-SCE-74723 Endosome acidification IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-75851 https://reactome.org/PathwayBrowser/#/R-SCE-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-75889 https://reactome.org/PathwayBrowser/#/R-SCE-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8847579 https://reactome.org/PathwayBrowser/#/R-SCE-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-425969 H+ [Golgi lumen] R-SCE-8851225 https://reactome.org/PathwayBrowser/#/R-SCE-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-ALL-425969 H+ [Golgi lumen] R-SCE-8851234 https://reactome.org/PathwayBrowser/#/R-SCE-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-8851356 https://reactome.org/PathwayBrowser/#/R-SCE-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-ALL-351626 H+ [extracellular region] R-SCE-8851396 https://reactome.org/PathwayBrowser/#/R-SCE-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Saccharomyces cerevisiae 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-SCE-8851494 https://reactome.org/PathwayBrowser/#/R-SCE-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-8862152 https://reactome.org/PathwayBrowser/#/R-SCE-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8875623 https://reactome.org/PathwayBrowser/#/R-SCE-8875623 SLC25A18,22 import L-Glu, H+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-8875623 https://reactome.org/PathwayBrowser/#/R-SCE-8875623 SLC25A18,22 import L-Glu, H+ IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8876789 https://reactome.org/PathwayBrowser/#/R-SCE-8876789 CARNMT1 methylates CARN to Anserine IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8876889 https://reactome.org/PathwayBrowser/#/R-SCE-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-888548 https://reactome.org/PathwayBrowser/#/R-SCE-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8939959 https://reactome.org/PathwayBrowser/#/R-SCE-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-8952873 https://reactome.org/PathwayBrowser/#/R-SCE-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8955760 https://reactome.org/PathwayBrowser/#/R-SCE-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-8955844 https://reactome.org/PathwayBrowser/#/R-SCE-8955844 RBKS phosphorylates ribose to R5P IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-9012016 https://reactome.org/PathwayBrowser/#/R-SCE-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Saccharomyces cerevisiae 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SCE-9013198 https://reactome.org/PathwayBrowser/#/R-SCE-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 15378 R-ALL-74722 H+ [endosome lumen] R-SCE-917841 https://reactome.org/PathwayBrowser/#/R-SCE-917841 Acidification of Tf:TfR1 containing endosome IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-917979 https://reactome.org/PathwayBrowser/#/R-SCE-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9695949 https://reactome.org/PathwayBrowser/#/R-SCE-9695949 SPHK2 phosphorylates sphingoid IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9705714 https://reactome.org/PathwayBrowser/#/R-SCE-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9709098 https://reactome.org/PathwayBrowser/#/R-SCE-9709098 DHFR dimer reduces FOLA to DHF IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9748945 https://reactome.org/PathwayBrowser/#/R-SCE-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9748957 https://reactome.org/PathwayBrowser/#/R-SCE-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9758682 https://reactome.org/PathwayBrowser/#/R-SCE-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9760094 https://reactome.org/PathwayBrowser/#/R-SCE-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9773976 https://reactome.org/PathwayBrowser/#/R-SCE-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9837337 https://reactome.org/PathwayBrowser/#/R-SCE-9837337 DCAKD phosphorylates DP-CoA IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9843721 https://reactome.org/PathwayBrowser/#/R-SCE-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-9853499 https://reactome.org/PathwayBrowser/#/R-SCE-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-9861616 https://reactome.org/PathwayBrowser/#/R-SCE-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-9861734 https://reactome.org/PathwayBrowser/#/R-SCE-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Saccharomyces cerevisiae 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SCE-9864415 https://reactome.org/PathwayBrowser/#/R-SCE-9864415 AAC1 imports a proton IEA Saccharomyces cerevisiae 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SCE-9864415 https://reactome.org/PathwayBrowser/#/R-SCE-9864415 AAC1 imports a proton IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9909159 https://reactome.org/PathwayBrowser/#/R-SCE-9909159 HK1 phosphorylates Mannose to Man6P IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SCE-9937295 https://reactome.org/PathwayBrowser/#/R-SCE-9937295 SRD5A3 reduces polyprenal to dolichal IEA Saccharomyces cerevisiae 15378 R-ALL-70106 H+ [cytosol] R-SPO-111215 https://reactome.org/PathwayBrowser/#/R-SPO-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-111524 https://reactome.org/PathwayBrowser/#/R-SPO-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-111883 https://reactome.org/PathwayBrowser/#/R-SPO-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1222516 https://reactome.org/PathwayBrowser/#/R-SPO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Schizosaccharomyces pombe 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SPO-1222516 https://reactome.org/PathwayBrowser/#/R-SPO-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1237119 https://reactome.org/PathwayBrowser/#/R-SPO-1237119 Acireductone is oxidized to MOB IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1497810 https://reactome.org/PathwayBrowser/#/R-SPO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1606273 https://reactome.org/PathwayBrowser/#/R-SPO-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1614567 https://reactome.org/PathwayBrowser/#/R-SPO-1614567 Excess homocysteine yields homolanthionine and H2S IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1614591 https://reactome.org/PathwayBrowser/#/R-SPO-1614591 Excess cysteine yields lanthionine and H2S IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1614614 https://reactome.org/PathwayBrowser/#/R-SPO-1614614 Cysteine is degraded to pyruvate and H2S IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1614631 https://reactome.org/PathwayBrowser/#/R-SPO-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-1640164 https://reactome.org/PathwayBrowser/#/R-SPO-1640164 ENPP7 hydrolyzes sphingomyelin IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SPO-164651 https://reactome.org/PathwayBrowser/#/R-SPO-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-169270 https://reactome.org/PathwayBrowser/#/R-SPO-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-174389 https://reactome.org/PathwayBrowser/#/R-SPO-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-174392 https://reactome.org/PathwayBrowser/#/R-SPO-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Schizosaccharomyces pombe 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SPO-189421 https://reactome.org/PathwayBrowser/#/R-SPO-189421 CPO transforms COPRO3 to PPGEN9 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-189425 https://reactome.org/PathwayBrowser/#/R-SPO-189425 UROD decarboxylates URO3 to COPRO3 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-189439 https://reactome.org/PathwayBrowser/#/R-SPO-189439 ALAD condenses 2 dALAs to form PBG IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-189442 https://reactome.org/PathwayBrowser/#/R-SPO-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-189465 https://reactome.org/PathwayBrowser/#/R-SPO-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-190182 https://reactome.org/PathwayBrowser/#/R-SPO-190182 UROD decarboxylates URO1 to COPRO1 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-191299 https://reactome.org/PathwayBrowser/#/R-SPO-191299 Squalene is oxidized to its epoxide IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-191323 https://reactome.org/PathwayBrowser/#/R-SPO-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-191352 https://reactome.org/PathwayBrowser/#/R-SPO-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-191402 https://reactome.org/PathwayBrowser/#/R-SPO-191402 Reduction of presqualene diphosphate to form squalene IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-191983 https://reactome.org/PathwayBrowser/#/R-SPO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-192033 https://reactome.org/PathwayBrowser/#/R-SPO-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-192036 https://reactome.org/PathwayBrowser/#/R-SPO-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-192067 https://reactome.org/PathwayBrowser/#/R-SPO-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-192160 https://reactome.org/PathwayBrowser/#/R-SPO-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193746 https://reactome.org/PathwayBrowser/#/R-SPO-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193755 https://reactome.org/PathwayBrowser/#/R-SPO-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193758 https://reactome.org/PathwayBrowser/#/R-SPO-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193781 https://reactome.org/PathwayBrowser/#/R-SPO-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193800 https://reactome.org/PathwayBrowser/#/R-SPO-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193821 https://reactome.org/PathwayBrowser/#/R-SPO-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193824 https://reactome.org/PathwayBrowser/#/R-SPO-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-193841 https://reactome.org/PathwayBrowser/#/R-SPO-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194023 https://reactome.org/PathwayBrowser/#/R-SPO-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194641 https://reactome.org/PathwayBrowser/#/R-SPO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194642 https://reactome.org/PathwayBrowser/#/R-SPO-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194669 https://reactome.org/PathwayBrowser/#/R-SPO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-ALL-194688 H+ [nuclear envelope] R-SPO-194674 https://reactome.org/PathwayBrowser/#/R-SPO-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194678 https://reactome.org/PathwayBrowser/#/R-SPO-194678 CYP51A1 demethylates LNSOL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194698 https://reactome.org/PathwayBrowser/#/R-SPO-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-194718 https://reactome.org/PathwayBrowser/#/R-SPO-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-195664 https://reactome.org/PathwayBrowser/#/R-SPO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196060 https://reactome.org/PathwayBrowser/#/R-SPO-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196753 https://reactome.org/PathwayBrowser/#/R-SPO-196753 2xPPCS ligates PPanK with Cys IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196754 https://reactome.org/PathwayBrowser/#/R-SPO-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196773 https://reactome.org/PathwayBrowser/#/R-SPO-196773 COASY phosphorylates DP-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196929 https://reactome.org/PathwayBrowser/#/R-SPO-196929 FLAD1 phosphorylates FMN IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196955 https://reactome.org/PathwayBrowser/#/R-SPO-196955 2xENPP1 hydrolyzes FAD to FMN IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-196964 https://reactome.org/PathwayBrowser/#/R-SPO-196964 RFK:Mg2+ phosphorylates RIB IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-197198 https://reactome.org/PathwayBrowser/#/R-SPO-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-197235 https://reactome.org/PathwayBrowser/#/R-SPO-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-197271 https://reactome.org/PathwayBrowser/#/R-SPO-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-197963 https://reactome.org/PathwayBrowser/#/R-SPO-197963 DHFR2 reduces FOLA to DHF IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-197972 https://reactome.org/PathwayBrowser/#/R-SPO-197972 DHF is reduced to tetrahydrofolate (THF) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-198824 https://reactome.org/PathwayBrowser/#/R-SPO-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200423 https://reactome.org/PathwayBrowser/#/R-SPO-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-200474 https://reactome.org/PathwayBrowser/#/R-SPO-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15378 R-ALL-9668967 H+ [nucleoplasm] R-SPO-200512 https://reactome.org/PathwayBrowser/#/R-SPO-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200555 https://reactome.org/PathwayBrowser/#/R-SPO-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200644 https://reactome.org/PathwayBrowser/#/R-SPO-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200646 https://reactome.org/PathwayBrowser/#/R-SPO-200646 Cytosolic folate export across the plasma membrane IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-200646 https://reactome.org/PathwayBrowser/#/R-SPO-200646 Cytosolic folate export across the plasma membrane IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200676 https://reactome.org/PathwayBrowser/#/R-SPO-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200718 https://reactome.org/PathwayBrowser/#/R-SPO-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-200729 https://reactome.org/PathwayBrowser/#/R-SPO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-200729 https://reactome.org/PathwayBrowser/#/R-SPO-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-202111 https://reactome.org/PathwayBrowser/#/R-SPO-202111 AKT1 phosphorylates eNOS IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-202127 https://reactome.org/PathwayBrowser/#/R-SPO-202127 eNOS synthesizes NO IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-203613 https://reactome.org/PathwayBrowser/#/R-SPO-203613 Depalmitoylation of eNOS IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-203946 https://reactome.org/PathwayBrowser/#/R-SPO-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-204617 https://reactome.org/PathwayBrowser/#/R-SPO-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-204647 https://reactome.org/PathwayBrowser/#/R-SPO-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-204662 https://reactome.org/PathwayBrowser/#/R-SPO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2161549 https://reactome.org/PathwayBrowser/#/R-SPO-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2161614 https://reactome.org/PathwayBrowser/#/R-SPO-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2162078 https://reactome.org/PathwayBrowser/#/R-SPO-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162186 https://reactome.org/PathwayBrowser/#/R-SPO-2162186 COQ3 methylates DeMQ10H2 IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162187 https://reactome.org/PathwayBrowser/#/R-SPO-2162187 COQ6 hydroxylates DHB IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162188 https://reactome.org/PathwayBrowser/#/R-SPO-2162188 COQ5 methylates MDMQ10H2 IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162193 https://reactome.org/PathwayBrowser/#/R-SPO-2162193 COQ3 methylates DHDB IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162194 https://reactome.org/PathwayBrowser/#/R-SPO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2162195 https://reactome.org/PathwayBrowser/#/R-SPO-2162195 COQ4 decarboxylates MHDB IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-2395517 https://reactome.org/PathwayBrowser/#/R-SPO-2395517 NADPH transfers electrons to FDXR IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2509827 https://reactome.org/PathwayBrowser/#/R-SPO-2509827 ITPA hydrolyses ITP to IMP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2509831 https://reactome.org/PathwayBrowser/#/R-SPO-2509831 ITPA hydrolyses XTP to XMP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2509838 https://reactome.org/PathwayBrowser/#/R-SPO-2509838 ITPA hydrolyses dITP to dIMP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-266070 https://reactome.org/PathwayBrowser/#/R-SPO-266070 LTC4 is exported from the cytosol by ABCC1 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-2730692 https://reactome.org/PathwayBrowser/#/R-SPO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Schizosaccharomyces pombe 15378 R-ALL-74722 H+ [endosome lumen] R-SPO-2730692 https://reactome.org/PathwayBrowser/#/R-SPO-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-3299680 https://reactome.org/PathwayBrowser/#/R-SPO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-3299682 https://reactome.org/PathwayBrowser/#/R-SPO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-3299691 https://reactome.org/PathwayBrowser/#/R-SPO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-3323079 https://reactome.org/PathwayBrowser/#/R-SPO-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SPO-3777112 https://reactome.org/PathwayBrowser/#/R-SPO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-380608 https://reactome.org/PathwayBrowser/#/R-SPO-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-389540 https://reactome.org/PathwayBrowser/#/R-SPO-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SPO-389550 https://reactome.org/PathwayBrowser/#/R-SPO-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-425965 https://reactome.org/PathwayBrowser/#/R-SPO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Schizosaccharomyces pombe 15378 R-ALL-425999 H+ [late endosome lumen] R-SPO-425965 https://reactome.org/PathwayBrowser/#/R-SPO-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-425983 https://reactome.org/PathwayBrowser/#/R-SPO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Schizosaccharomyces pombe 15378 R-ALL-425978 H+ [early endosome lumen] R-SPO-425983 https://reactome.org/PathwayBrowser/#/R-SPO-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-425994 https://reactome.org/PathwayBrowser/#/R-SPO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-425994 https://reactome.org/PathwayBrowser/#/R-SPO-425994 Na+/H+ exchanger transport (at cell membrane) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-426015 https://reactome.org/PathwayBrowser/#/R-SPO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Schizosaccharomyces pombe 15378 R-ALL-425969 H+ [Golgi lumen] R-SPO-426015 https://reactome.org/PathwayBrowser/#/R-SPO-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-426043 https://reactome.org/PathwayBrowser/#/R-SPO-426043 2-AG hydrolysis to arachidonate by MAGL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-427555 https://reactome.org/PathwayBrowser/#/R-SPO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-427555 https://reactome.org/PathwayBrowser/#/R-SPO-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 15378 R-ALL-428040 H+ [lysosomal lumen] R-SPO-428007 https://reactome.org/PathwayBrowser/#/R-SPO-428007 Proton-coupled histidine and di-peptide cotransport IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428123 https://reactome.org/PathwayBrowser/#/R-SPO-428123 KDSR reduces 3-ketosphingoid IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428185 https://reactome.org/PathwayBrowser/#/R-SPO-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428259 https://reactome.org/PathwayBrowser/#/R-SPO-428259 DEGS1 dehydrogenates dihydroceramide IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428260 https://reactome.org/PathwayBrowser/#/R-SPO-428260 DEGS2 oxygenates dihydroceramide IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-428273 https://reactome.org/PathwayBrowser/#/R-SPO-428273 SPHK1 phosphorylates sphingoid IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-429101 https://reactome.org/PathwayBrowser/#/R-SPO-429101 HMIT co-transports myo-inositol with a proton IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-429101 https://reactome.org/PathwayBrowser/#/R-SPO-429101 HMIT co-transports myo-inositol with a proton IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-434650 https://reactome.org/PathwayBrowser/#/R-SPO-434650 MATEs mediate extrusion of xenobiotics IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-446195 https://reactome.org/PathwayBrowser/#/R-SPO-446195 DOLK phosphorylates DCHOL to DOLP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-446200 https://reactome.org/PathwayBrowser/#/R-SPO-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-446221 https://reactome.org/PathwayBrowser/#/R-SPO-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-469659 https://reactome.org/PathwayBrowser/#/R-SPO-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-504054 https://reactome.org/PathwayBrowser/#/R-SPO-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-508040 https://reactome.org/PathwayBrowser/#/R-SPO-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5362518 https://reactome.org/PathwayBrowser/#/R-SPO-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5362522 https://reactome.org/PathwayBrowser/#/R-SPO-5362522 ALDHs oxidise atRAL to atRA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5362564 https://reactome.org/PathwayBrowser/#/R-SPO-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5362721 https://reactome.org/PathwayBrowser/#/R-SPO-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5419165 https://reactome.org/PathwayBrowser/#/R-SPO-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-548800 https://reactome.org/PathwayBrowser/#/R-SPO-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-548814 https://reactome.org/PathwayBrowser/#/R-SPO-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-548831 https://reactome.org/PathwayBrowser/#/R-SPO-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5615668 https://reactome.org/PathwayBrowser/#/R-SPO-5615668 AKR1C3 reduces atRAL to atROL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5652172 https://reactome.org/PathwayBrowser/#/R-SPO-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5652195 https://reactome.org/PathwayBrowser/#/R-SPO-5652195 SORD oxidizes D-sorbitol to Fru IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5661256 https://reactome.org/PathwayBrowser/#/R-SPO-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5662471 https://reactome.org/PathwayBrowser/#/R-SPO-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5690565 https://reactome.org/PathwayBrowser/#/R-SPO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5692237 https://reactome.org/PathwayBrowser/#/R-SPO-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Schizosaccharomyces pombe 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SPO-5693347 https://reactome.org/PathwayBrowser/#/R-SPO-5693347 CRYM reduces P2C to PPCA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-5693761 https://reactome.org/PathwayBrowser/#/R-SPO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-5693967 https://reactome.org/PathwayBrowser/#/R-SPO-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-5694018 https://reactome.org/PathwayBrowser/#/R-SPO-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-5696091 https://reactome.org/PathwayBrowser/#/R-SPO-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-5696822 https://reactome.org/PathwayBrowser/#/R-SPO-5696822 AKR1B15 reduces EST17b to E1 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6783221 https://reactome.org/PathwayBrowser/#/R-SPO-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Schizosaccharomyces pombe 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SPO-6783880 https://reactome.org/PathwayBrowser/#/R-SPO-6783880 PIPOX oxidises PPCA to P6C IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6783939 https://reactome.org/PathwayBrowser/#/R-SPO-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6783955 https://reactome.org/PathwayBrowser/#/R-SPO-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-6784224 https://reactome.org/PathwayBrowser/#/R-SPO-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-6793590 https://reactome.org/PathwayBrowser/#/R-SPO-6793590 LIPT2 transfers octanoyl group to GCSH IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6798335 https://reactome.org/PathwayBrowser/#/R-SPO-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6801342 https://reactome.org/PathwayBrowser/#/R-SPO-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-6806967 https://reactome.org/PathwayBrowser/#/R-SPO-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6807053 https://reactome.org/PathwayBrowser/#/R-SPO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Schizosaccharomyces pombe 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SPO-6809287 https://reactome.org/PathwayBrowser/#/R-SPO-6809287 NUDT12 hydrolyses NADH to NMNH IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-6813749 https://reactome.org/PathwayBrowser/#/R-SPO-6813749 ALDH1A1 oxidises GA to DGA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70286 https://reactome.org/PathwayBrowser/#/R-SPO-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70377 https://reactome.org/PathwayBrowser/#/R-SPO-70377 G6PD multimers dehydrogenate G6P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70420 https://reactome.org/PathwayBrowser/#/R-SPO-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70449 https://reactome.org/PathwayBrowser/#/R-SPO-70449 GADPH tetramer dehydrogenates GA3P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70467 https://reactome.org/PathwayBrowser/#/R-SPO-70467 PFK tetramer phosphorylates Fru(6)P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70482 https://reactome.org/PathwayBrowser/#/R-SPO-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70501 https://reactome.org/PathwayBrowser/#/R-SPO-70501 PC carboxylates PYR to OA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70599 https://reactome.org/PathwayBrowser/#/R-SPO-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-70606 https://reactome.org/PathwayBrowser/#/R-SPO-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70664 https://reactome.org/PathwayBrowser/#/R-SPO-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70670 https://reactome.org/PathwayBrowser/#/R-SPO-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70881 https://reactome.org/PathwayBrowser/#/R-SPO-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70938 https://reactome.org/PathwayBrowser/#/R-SPO-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70940 https://reactome.org/PathwayBrowser/#/R-SPO-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70975 https://reactome.org/PathwayBrowser/#/R-SPO-70975 CS acetylates OA to citrate IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-70979 https://reactome.org/PathwayBrowser/#/R-SPO-70979 MDH2 dimer dehydrogenates MAL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71286 https://reactome.org/PathwayBrowser/#/R-SPO-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71296 https://reactome.org/PathwayBrowser/#/R-SPO-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-71401 https://reactome.org/PathwayBrowser/#/R-SPO-71401 OGDH dimer decarboxylates 2-OG IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71670 https://reactome.org/PathwayBrowser/#/R-SPO-71670 PKM dephosphorylates PEP to PYR IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71682 https://reactome.org/PathwayBrowser/#/R-SPO-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71691 https://reactome.org/PathwayBrowser/#/R-SPO-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71707 https://reactome.org/PathwayBrowser/#/R-SPO-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-71723 https://reactome.org/PathwayBrowser/#/R-SPO-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-71802 https://reactome.org/PathwayBrowser/#/R-SPO-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73571 https://reactome.org/PathwayBrowser/#/R-SPO-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73573 https://reactome.org/PathwayBrowser/#/R-SPO-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73577 https://reactome.org/PathwayBrowser/#/R-SPO-73577 CAD hexamer transforms L-Gln to CAP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73580 https://reactome.org/PathwayBrowser/#/R-SPO-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73591 https://reactome.org/PathwayBrowser/#/R-SPO-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73620 https://reactome.org/PathwayBrowser/#/R-SPO-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73647 https://reactome.org/PathwayBrowser/#/R-SPO-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Schizosaccharomyces pombe 15378 R-ALL-9668967 H+ [nucleoplasm] R-SPO-73666 https://reactome.org/PathwayBrowser/#/R-SPO-73666 dUTP + H2O => dUMP + pyrophosphate IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73792 https://reactome.org/PathwayBrowser/#/R-SPO-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73794 https://reactome.org/PathwayBrowser/#/R-SPO-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73810 https://reactome.org/PathwayBrowser/#/R-SPO-73810 FGAM + ATP => AIR + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73812 https://reactome.org/PathwayBrowser/#/R-SPO-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73813 https://reactome.org/PathwayBrowser/#/R-SPO-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-73814 https://reactome.org/PathwayBrowser/#/R-SPO-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-73912 https://reactome.org/PathwayBrowser/#/R-SPO-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-73920 https://reactome.org/PathwayBrowser/#/R-SPO-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-74255 https://reactome.org/PathwayBrowser/#/R-SPO-74255 Guanine + H2O => Xanthine + NH4+ IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-74723 https://reactome.org/PathwayBrowser/#/R-SPO-74723 Endosome acidification IEA Schizosaccharomyces pombe 15378 R-ALL-74722 H+ [endosome lumen] R-SPO-74723 https://reactome.org/PathwayBrowser/#/R-SPO-74723 Endosome acidification IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-75851 https://reactome.org/PathwayBrowser/#/R-SPO-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-75889 https://reactome.org/PathwayBrowser/#/R-SPO-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-804969 https://reactome.org/PathwayBrowser/#/R-SPO-804969 HSD17B1 hydrogenates E1 to EST17b IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8847579 https://reactome.org/PathwayBrowser/#/R-SPO-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-425969 H+ [Golgi lumen] R-SPO-8851225 https://reactome.org/PathwayBrowser/#/R-SPO-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-ALL-425969 H+ [Golgi lumen] R-SPO-8851234 https://reactome.org/PathwayBrowser/#/R-SPO-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-8851356 https://reactome.org/PathwayBrowser/#/R-SPO-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-ALL-351626 H+ [extracellular region] R-SPO-8851396 https://reactome.org/PathwayBrowser/#/R-SPO-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Schizosaccharomyces pombe 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-SPO-8851494 https://reactome.org/PathwayBrowser/#/R-SPO-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8862137 https://reactome.org/PathwayBrowser/#/R-SPO-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-8862152 https://reactome.org/PathwayBrowser/#/R-SPO-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8876789 https://reactome.org/PathwayBrowser/#/R-SPO-8876789 CARNMT1 methylates CARN to Anserine IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8876889 https://reactome.org/PathwayBrowser/#/R-SPO-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-888548 https://reactome.org/PathwayBrowser/#/R-SPO-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8939959 https://reactome.org/PathwayBrowser/#/R-SPO-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-8952873 https://reactome.org/PathwayBrowser/#/R-SPO-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8955760 https://reactome.org/PathwayBrowser/#/R-SPO-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-8955844 https://reactome.org/PathwayBrowser/#/R-SPO-8955844 RBKS phosphorylates ribose to R5P IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-9012016 https://reactome.org/PathwayBrowser/#/R-SPO-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Schizosaccharomyces pombe 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SPO-9013198 https://reactome.org/PathwayBrowser/#/R-SPO-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 15378 R-ALL-74722 H+ [endosome lumen] R-SPO-917841 https://reactome.org/PathwayBrowser/#/R-SPO-917841 Acidification of Tf:TfR1 containing endosome IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9695949 https://reactome.org/PathwayBrowser/#/R-SPO-9695949 SPHK2 phosphorylates sphingoid IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9705713 https://reactome.org/PathwayBrowser/#/R-SPO-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9705714 https://reactome.org/PathwayBrowser/#/R-SPO-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9709098 https://reactome.org/PathwayBrowser/#/R-SPO-9709098 DHFR dimer reduces FOLA to DHF IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9748945 https://reactome.org/PathwayBrowser/#/R-SPO-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9748957 https://reactome.org/PathwayBrowser/#/R-SPO-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9758682 https://reactome.org/PathwayBrowser/#/R-SPO-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9759259 https://reactome.org/PathwayBrowser/#/R-SPO-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9760094 https://reactome.org/PathwayBrowser/#/R-SPO-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9773976 https://reactome.org/PathwayBrowser/#/R-SPO-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9837337 https://reactome.org/PathwayBrowser/#/R-SPO-9837337 DCAKD phosphorylates DP-CoA IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9843721 https://reactome.org/PathwayBrowser/#/R-SPO-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-9853499 https://reactome.org/PathwayBrowser/#/R-SPO-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-9861616 https://reactome.org/PathwayBrowser/#/R-SPO-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-9861734 https://reactome.org/PathwayBrowser/#/R-SPO-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SPO-9864415 https://reactome.org/PathwayBrowser/#/R-SPO-9864415 AAC1 imports a proton IEA Schizosaccharomyces pombe 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SPO-9864415 https://reactome.org/PathwayBrowser/#/R-SPO-9864415 AAC1 imports a proton IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9909159 https://reactome.org/PathwayBrowser/#/R-SPO-9909159 HK1 phosphorylates Mannose to Man6P IEA Schizosaccharomyces pombe 15378 R-ALL-70106 H+ [cytosol] R-SPO-9937295 https://reactome.org/PathwayBrowser/#/R-SPO-9937295 SRD5A3 reduces polyprenal to dolichal IEA Schizosaccharomyces pombe 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-109343 https://reactome.org/PathwayBrowser/#/R-SSC-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-111215 https://reactome.org/PathwayBrowser/#/R-SSC-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-111524 https://reactome.org/PathwayBrowser/#/R-SSC-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-111883 https://reactome.org/PathwayBrowser/#/R-SSC-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1222376 https://reactome.org/PathwayBrowser/#/R-SSC-1222376 NOX2 generates superoxide from oxygen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-1222516 https://reactome.org/PathwayBrowser/#/R-SSC-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Sus scrofa 15378 R-ALL-2000349 H+ [phagolysosome] R-SSC-1236967 https://reactome.org/PathwayBrowser/#/R-SSC-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1237045 https://reactome.org/PathwayBrowser/#/R-SSC-1237045 Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1237047 https://reactome.org/PathwayBrowser/#/R-SSC-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1237059 https://reactome.org/PathwayBrowser/#/R-SSC-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1237081 https://reactome.org/PathwayBrowser/#/R-SSC-1237081 Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1237119 https://reactome.org/PathwayBrowser/#/R-SSC-1237119 Acireductone is oxidized to MOB IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1237325 https://reactome.org/PathwayBrowser/#/R-SSC-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1247668 https://reactome.org/PathwayBrowser/#/R-SSC-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-139970 https://reactome.org/PathwayBrowser/#/R-SSC-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-143468 https://reactome.org/PathwayBrowser/#/R-SSC-143468 MEOS oxidizes ethanol to acetaldehyde IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1475017 https://reactome.org/PathwayBrowser/#/R-SSC-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1475022 https://reactome.org/PathwayBrowser/#/R-SSC-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-1475025 https://reactome.org/PathwayBrowser/#/R-SSC-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1475026 https://reactome.org/PathwayBrowser/#/R-SSC-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-1475028 https://reactome.org/PathwayBrowser/#/R-SSC-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-1475032 https://reactome.org/PathwayBrowser/#/R-SSC-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1475435 https://reactome.org/PathwayBrowser/#/R-SSC-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1475436 https://reactome.org/PathwayBrowser/#/R-SSC-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1497810 https://reactome.org/PathwayBrowser/#/R-SSC-1497810 Uncoupled eNOS favours the formation of superoxide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1497869 https://reactome.org/PathwayBrowser/#/R-SSC-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1562626 https://reactome.org/PathwayBrowser/#/R-SSC-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-156526 https://reactome.org/PathwayBrowser/#/R-SSC-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-158609 https://reactome.org/PathwayBrowser/#/R-SSC-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-159790 https://reactome.org/PathwayBrowser/#/R-SSC-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-1605797 https://reactome.org/PathwayBrowser/#/R-SSC-1605797 SMPD1 hydrolyzes SPHM IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1606273 https://reactome.org/PathwayBrowser/#/R-SSC-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1606288 https://reactome.org/PathwayBrowser/#/R-SSC-1606288 SMPD4 hydrolyzes sphingomyelin (ER membrane) IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-1606807 https://reactome.org/PathwayBrowser/#/R-SSC-1606807 ARSA removes sulfate from PSAP(195-273):Sulfatide IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-1614362 https://reactome.org/PathwayBrowser/#/R-SSC-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1614567 https://reactome.org/PathwayBrowser/#/R-SSC-1614567 Excess homocysteine yields homolanthionine and H2S IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1614591 https://reactome.org/PathwayBrowser/#/R-SSC-1614591 Excess cysteine yields lanthionine and H2S IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-1614605 https://reactome.org/PathwayBrowser/#/R-SSC-1614605 Persulfide sulfur is dioxygenated IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1614614 https://reactome.org/PathwayBrowser/#/R-SSC-1614614 Cysteine is degraded to pyruvate and H2S IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1614631 https://reactome.org/PathwayBrowser/#/R-SSC-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1614645 https://reactome.org/PathwayBrowser/#/R-SSC-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-162730 https://reactome.org/PathwayBrowser/#/R-SSC-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-163120 https://reactome.org/PathwayBrowser/#/R-SSC-163120 Disassociation of Telomerase RNP and the Chromosome End IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-163214 https://reactome.org/PathwayBrowser/#/R-SSC-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-163217 https://reactome.org/PathwayBrowser/#/R-SSC-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-1638104 https://reactome.org/PathwayBrowser/#/R-SSC-1638104 UGCG transfers glucose to ceramide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1638845 https://reactome.org/PathwayBrowser/#/R-SSC-1638845 CERK phosphorylates CERA to form C1P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1640164 https://reactome.org/PathwayBrowser/#/R-SSC-1640164 ENPP7 hydrolyzes sphingomyelin IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-164651 https://reactome.org/PathwayBrowser/#/R-SSC-164651 Electron transfer from ubiquinol to cytochrome c of complex III IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-164834 https://reactome.org/PathwayBrowser/#/R-SSC-164834 Enzyme-bound ATP is released IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-1655453 https://reactome.org/PathwayBrowser/#/R-SSC-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-1655879 https://reactome.org/PathwayBrowser/#/R-SSC-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Sus scrofa 15378 R-ALL-9631150 H+ [endolysosome lumen] R-SSC-1678920 https://reactome.org/PathwayBrowser/#/R-SSC-1678920 TLR processing at low pH IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-169270 https://reactome.org/PathwayBrowser/#/R-SSC-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-173597 https://reactome.org/PathwayBrowser/#/R-SSC-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-174389 https://reactome.org/PathwayBrowser/#/R-SSC-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-174392 https://reactome.org/PathwayBrowser/#/R-SSC-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-174438 https://reactome.org/PathwayBrowser/#/R-SSC-174438 Formation of the Flap Intermediate on the C-strand IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-189421 https://reactome.org/PathwayBrowser/#/R-SSC-189421 CPO transforms COPRO3 to PPGEN9 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-189425 https://reactome.org/PathwayBrowser/#/R-SSC-189425 UROD decarboxylates URO3 to COPRO3 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-189439 https://reactome.org/PathwayBrowser/#/R-SSC-189439 ALAD condenses 2 dALAs to form PBG IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-189442 https://reactome.org/PathwayBrowser/#/R-SSC-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-189465 https://reactome.org/PathwayBrowser/#/R-SSC-189465 FECH binds Fe2+ to PRIN9 to form heme IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-190182 https://reactome.org/PathwayBrowser/#/R-SSC-190182 UROD decarboxylates URO1 to COPRO1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191299 https://reactome.org/PathwayBrowser/#/R-SSC-191299 Squalene is oxidized to its epoxide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191323 https://reactome.org/PathwayBrowser/#/R-SSC-191323 HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191352 https://reactome.org/PathwayBrowser/#/R-SSC-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191402 https://reactome.org/PathwayBrowser/#/R-SSC-191402 Reduction of presqualene diphosphate to form squalene IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191972 https://reactome.org/PathwayBrowser/#/R-SSC-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-191983 https://reactome.org/PathwayBrowser/#/R-SSC-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-191999 https://reactome.org/PathwayBrowser/#/R-SSC-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192033 https://reactome.org/PathwayBrowser/#/R-SSC-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192036 https://reactome.org/PathwayBrowser/#/R-SSC-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-192042 https://reactome.org/PathwayBrowser/#/R-SSC-192042 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192051 https://reactome.org/PathwayBrowser/#/R-SSC-192051 CYP7A1 7-hydroxylates CHOL IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-192054 https://reactome.org/PathwayBrowser/#/R-SSC-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192061 https://reactome.org/PathwayBrowser/#/R-SSC-192061 CYP46A1 24-hydroxylates CHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192065 https://reactome.org/PathwayBrowser/#/R-SSC-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192067 https://reactome.org/PathwayBrowser/#/R-SSC-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192097 https://reactome.org/PathwayBrowser/#/R-SSC-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-192123 https://reactome.org/PathwayBrowser/#/R-SSC-192123 CYP27A1 27-hydroxylates CHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192157 https://reactome.org/PathwayBrowser/#/R-SSC-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192160 https://reactome.org/PathwayBrowser/#/R-SSC-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-192178 https://reactome.org/PathwayBrowser/#/R-SSC-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193054 https://reactome.org/PathwayBrowser/#/R-SSC-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193060 https://reactome.org/PathwayBrowser/#/R-SSC-193060 CYP19A1 hydroxylates ANDST to E1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193064 https://reactome.org/PathwayBrowser/#/R-SSC-193064 HSD17B3-like proteins reducde ANDST to TEST IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193065 https://reactome.org/PathwayBrowser/#/R-SSC-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193068 https://reactome.org/PathwayBrowser/#/R-SSC-193068 CYP17A1 17-hydroxylates PREG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193070 https://reactome.org/PathwayBrowser/#/R-SSC-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193072 https://reactome.org/PathwayBrowser/#/R-SSC-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193073 https://reactome.org/PathwayBrowser/#/R-SSC-193073 HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193099 https://reactome.org/PathwayBrowser/#/R-SSC-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193101 https://reactome.org/PathwayBrowser/#/R-SSC-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193143 https://reactome.org/PathwayBrowser/#/R-SSC-193143 CYP19A1 hydroxylates TEST to EST17b IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193393 https://reactome.org/PathwayBrowser/#/R-SSC-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193460 https://reactome.org/PathwayBrowser/#/R-SSC-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193497 https://reactome.org/PathwayBrowser/#/R-SSC-193497 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193709 https://reactome.org/PathwayBrowser/#/R-SSC-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193713 https://reactome.org/PathwayBrowser/#/R-SSC-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193719 https://reactome.org/PathwayBrowser/#/R-SSC-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193737 https://reactome.org/PathwayBrowser/#/R-SSC-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193746 https://reactome.org/PathwayBrowser/#/R-SSC-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193755 https://reactome.org/PathwayBrowser/#/R-SSC-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193758 https://reactome.org/PathwayBrowser/#/R-SSC-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193780 https://reactome.org/PathwayBrowser/#/R-SSC-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193781 https://reactome.org/PathwayBrowser/#/R-SSC-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193787 https://reactome.org/PathwayBrowser/#/R-SSC-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193789 https://reactome.org/PathwayBrowser/#/R-SSC-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193792 https://reactome.org/PathwayBrowser/#/R-SSC-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193800 https://reactome.org/PathwayBrowser/#/R-SSC-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193816 https://reactome.org/PathwayBrowser/#/R-SSC-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193821 https://reactome.org/PathwayBrowser/#/R-SSC-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193824 https://reactome.org/PathwayBrowser/#/R-SSC-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193841 https://reactome.org/PathwayBrowser/#/R-SSC-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193845 https://reactome.org/PathwayBrowser/#/R-SSC-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193964 https://reactome.org/PathwayBrowser/#/R-SSC-193964 CYP21A2 21-hydroxylates PROG IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193965 https://reactome.org/PathwayBrowser/#/R-SSC-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-193981 https://reactome.org/PathwayBrowser/#/R-SSC-193981 CYP21A2 oxidises 17HPROG IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193995 https://reactome.org/PathwayBrowser/#/R-SSC-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-193997 https://reactome.org/PathwayBrowser/#/R-SSC-193997 CYP11B1 oxidises 11DCORT IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-194017 https://reactome.org/PathwayBrowser/#/R-SSC-194017 CYP11B2 oxidises 11DCORST to CORST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194023 https://reactome.org/PathwayBrowser/#/R-SSC-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194632 https://reactome.org/PathwayBrowser/#/R-SSC-194632 Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194641 https://reactome.org/PathwayBrowser/#/R-SSC-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194642 https://reactome.org/PathwayBrowser/#/R-SSC-194642 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194669 https://reactome.org/PathwayBrowser/#/R-SSC-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-ALL-194688 H+ [nuclear envelope] R-SSC-194674 https://reactome.org/PathwayBrowser/#/R-SSC-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194678 https://reactome.org/PathwayBrowser/#/R-SSC-194678 CYP51A1 demethylates LNSOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194689 https://reactome.org/PathwayBrowser/#/R-SSC-194689 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194698 https://reactome.org/PathwayBrowser/#/R-SSC-194698 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-194718 https://reactome.org/PathwayBrowser/#/R-SSC-194718 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-195664 https://reactome.org/PathwayBrowser/#/R-SSC-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196060 https://reactome.org/PathwayBrowser/#/R-SSC-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196350 https://reactome.org/PathwayBrowser/#/R-SSC-196350 Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196372 https://reactome.org/PathwayBrowser/#/R-SSC-196372 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196402 https://reactome.org/PathwayBrowser/#/R-SSC-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196417 https://reactome.org/PathwayBrowser/#/R-SSC-196417 Reduction of desmosterol to cholesterol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196753 https://reactome.org/PathwayBrowser/#/R-SSC-196753 2xPPCS ligates PPanK with Cys IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196754 https://reactome.org/PathwayBrowser/#/R-SSC-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196773 https://reactome.org/PathwayBrowser/#/R-SSC-196773 COASY phosphorylates DP-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196840 https://reactome.org/PathwayBrowser/#/R-SSC-196840 3xPPCDC:3FMN decarboxylates PPC IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196857 https://reactome.org/PathwayBrowser/#/R-SSC-196857 PANK2 phosphorylates PanK IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196929 https://reactome.org/PathwayBrowser/#/R-SSC-196929 FLAD1 phosphorylates FMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196955 https://reactome.org/PathwayBrowser/#/R-SSC-196955 2xENPP1 hydrolyzes FAD to FMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-196964 https://reactome.org/PathwayBrowser/#/R-SSC-196964 RFK:Mg2+ phosphorylates RIB IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197198 https://reactome.org/PathwayBrowser/#/R-SSC-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197235 https://reactome.org/PathwayBrowser/#/R-SSC-197235 NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197250 https://reactome.org/PathwayBrowser/#/R-SSC-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197268 https://reactome.org/PathwayBrowser/#/R-SSC-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197271 https://reactome.org/PathwayBrowser/#/R-SSC-197271 NADSYN1 hexamer amidates NAAD to NAD+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197963 https://reactome.org/PathwayBrowser/#/R-SSC-197963 DHFR2 reduces FOLA to DHF IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-197972 https://reactome.org/PathwayBrowser/#/R-SSC-197972 DHF is reduced to tetrahydrofolate (THF) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-198824 https://reactome.org/PathwayBrowser/#/R-SSC-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-199203 https://reactome.org/PathwayBrowser/#/R-SSC-199203 PANK1/3 phosphorylate PanK IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200423 https://reactome.org/PathwayBrowser/#/R-SSC-200423 pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-200474 https://reactome.org/PathwayBrowser/#/R-SSC-200474 NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-200512 https://reactome.org/PathwayBrowser/#/R-SSC-200512 NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200555 https://reactome.org/PathwayBrowser/#/R-SSC-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200644 https://reactome.org/PathwayBrowser/#/R-SSC-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200646 https://reactome.org/PathwayBrowser/#/R-SSC-200646 Cytosolic folate export across the plasma membrane IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-200646 https://reactome.org/PathwayBrowser/#/R-SSC-200646 Cytosolic folate export across the plasma membrane IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200676 https://reactome.org/PathwayBrowser/#/R-SSC-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200718 https://reactome.org/PathwayBrowser/#/R-SSC-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-200729 https://reactome.org/PathwayBrowser/#/R-SSC-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-200729 https://reactome.org/PathwayBrowser/#/R-SSC-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-202111 https://reactome.org/PathwayBrowser/#/R-SSC-202111 AKT1 phosphorylates eNOS IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-202127 https://reactome.org/PathwayBrowser/#/R-SSC-202127 eNOS synthesizes NO IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-203613 https://reactome.org/PathwayBrowser/#/R-SSC-203613 Depalmitoylation of eNOS IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-203946 https://reactome.org/PathwayBrowser/#/R-SSC-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-204617 https://reactome.org/PathwayBrowser/#/R-SSC-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-204647 https://reactome.org/PathwayBrowser/#/R-SSC-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-204662 https://reactome.org/PathwayBrowser/#/R-SSC-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209765 https://reactome.org/PathwayBrowser/#/R-SSC-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209772 https://reactome.org/PathwayBrowser/#/R-SSC-209772 Thyroxine is deiodinated to triiodothyronine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209821 https://reactome.org/PathwayBrowser/#/R-SSC-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209845 https://reactome.org/PathwayBrowser/#/R-SSC-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209868 https://reactome.org/PathwayBrowser/#/R-SSC-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-209903 https://reactome.org/PathwayBrowser/#/R-SSC-209903 Noradrenaline is converted to adrenaline IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-209973 https://reactome.org/PathwayBrowser/#/R-SSC-209973 Tyrosine is diiodinated IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-210404 https://reactome.org/PathwayBrowser/#/R-SSC-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-211873 https://reactome.org/PathwayBrowser/#/R-SSC-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211874 https://reactome.org/PathwayBrowser/#/R-SSC-211874 CYP2S1 4-hydroxylates atRA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211881 https://reactome.org/PathwayBrowser/#/R-SSC-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211882 https://reactome.org/PathwayBrowser/#/R-SSC-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211904 https://reactome.org/PathwayBrowser/#/R-SSC-211904 CYP4F12 18-hydroxylates ARA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211910 https://reactome.org/PathwayBrowser/#/R-SSC-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211919 https://reactome.org/PathwayBrowser/#/R-SSC-211919 CYP4F8 19-hydroxylates PGH2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-211923 https://reactome.org/PathwayBrowser/#/R-SSC-211923 CYP26C1 4-hydroxylates 9cRA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211924 https://reactome.org/PathwayBrowser/#/R-SSC-211924 CYP4B1 12-hydroxylates ARA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211929 https://reactome.org/PathwayBrowser/#/R-SSC-211929 CYP2C19 5-hydroxylates omeprazole IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211948 https://reactome.org/PathwayBrowser/#/R-SSC-211948 CYP3A4 can N-demethylate loperamide IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-211950 https://reactome.org/PathwayBrowser/#/R-SSC-211950 CYP24A1 24-hydroxylates CTL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-211951 https://reactome.org/PathwayBrowser/#/R-SSC-211951 CYP1B1 4-hydroxylates EST17b IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211959 https://reactome.org/PathwayBrowser/#/R-SSC-211959 CYP3A43 6b-hydroxylates TEST IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211960 https://reactome.org/PathwayBrowser/#/R-SSC-211960 CYP2U1 19-hydroxylates ARA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211962 https://reactome.org/PathwayBrowser/#/R-SSC-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211966 https://reactome.org/PathwayBrowser/#/R-SSC-211966 CYP2D6 4-hydroxylates debrisoquine IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211968 https://reactome.org/PathwayBrowser/#/R-SSC-211968 CYP2W1 oxidises INDOL IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211983 https://reactome.org/PathwayBrowser/#/R-SSC-211983 CYP2J2 oxidises ARA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211988 https://reactome.org/PathwayBrowser/#/R-SSC-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-211991 https://reactome.org/PathwayBrowser/#/R-SSC-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-212004 https://reactome.org/PathwayBrowser/#/R-SSC-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-212005 https://reactome.org/PathwayBrowser/#/R-SSC-212005 CYP2F1 dehydrogenates 3-methylindole IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-212007 https://reactome.org/PathwayBrowser/#/R-SSC-212007 CYP26A1,B1 4-hydroxylate atRA IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-213175 https://reactome.org/PathwayBrowser/#/R-SSC-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-215526 https://reactome.org/PathwayBrowser/#/R-SSC-215526 CYP4F3 20-hydroxylates LTB4 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161187 https://reactome.org/PathwayBrowser/#/R-SSC-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161549 https://reactome.org/PathwayBrowser/#/R-SSC-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161614 https://reactome.org/PathwayBrowser/#/R-SSC-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161617 https://reactome.org/PathwayBrowser/#/R-SSC-2161617 LTB4 is oxidised to 12-oxoLTB4 by PTGR1 TAS Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161651 https://reactome.org/PathwayBrowser/#/R-SSC-2161651 PGE2 is converted to PGF2a by CBR1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161745 https://reactome.org/PathwayBrowser/#/R-SSC-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161779 https://reactome.org/PathwayBrowser/#/R-SSC-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161792 https://reactome.org/PathwayBrowser/#/R-SSC-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-2161795 https://reactome.org/PathwayBrowser/#/R-SSC-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-2161814 https://reactome.org/PathwayBrowser/#/R-SSC-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161847 https://reactome.org/PathwayBrowser/#/R-SSC-2161847 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 TAS Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161890 https://reactome.org/PathwayBrowser/#/R-SSC-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161899 https://reactome.org/PathwayBrowser/#/R-SSC-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-2161940 https://reactome.org/PathwayBrowser/#/R-SSC-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2161951 https://reactome.org/PathwayBrowser/#/R-SSC-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2162078 https://reactome.org/PathwayBrowser/#/R-SSC-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162186 https://reactome.org/PathwayBrowser/#/R-SSC-2162186 COQ3 methylates DeMQ10H2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162187 https://reactome.org/PathwayBrowser/#/R-SSC-2162187 COQ6 hydroxylates DHB IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162188 https://reactome.org/PathwayBrowser/#/R-SSC-2162188 COQ5 methylates MDMQ10H2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162193 https://reactome.org/PathwayBrowser/#/R-SSC-2162193 COQ3 methylates DHDB IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162194 https://reactome.org/PathwayBrowser/#/R-SSC-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2162195 https://reactome.org/PathwayBrowser/#/R-SSC-2162195 COQ4 decarboxylates MHDB IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-217255 https://reactome.org/PathwayBrowser/#/R-SSC-217255 FMO1:FAD N-oxidises TAM IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-217258 https://reactome.org/PathwayBrowser/#/R-SSC-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2395512 https://reactome.org/PathwayBrowser/#/R-SSC-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2395517 https://reactome.org/PathwayBrowser/#/R-SSC-2395517 NADPH transfers electrons to FDXR IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395818 https://reactome.org/PathwayBrowser/#/R-SSC-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395849 https://reactome.org/PathwayBrowser/#/R-SSC-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395869 https://reactome.org/PathwayBrowser/#/R-SSC-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395872 https://reactome.org/PathwayBrowser/#/R-SSC-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395873 https://reactome.org/PathwayBrowser/#/R-SSC-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395876 https://reactome.org/PathwayBrowser/#/R-SSC-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395879 https://reactome.org/PathwayBrowser/#/R-SSC-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2395965 https://reactome.org/PathwayBrowser/#/R-SSC-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2408524 https://reactome.org/PathwayBrowser/#/R-SSC-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2453833 https://reactome.org/PathwayBrowser/#/R-SSC-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2454081 https://reactome.org/PathwayBrowser/#/R-SSC-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2464822 https://reactome.org/PathwayBrowser/#/R-SSC-2464822 RDH12 reduces atRAL to atROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2465940 https://reactome.org/PathwayBrowser/#/R-SSC-2465940 atRAL is reduced to atROL IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-2509793 https://reactome.org/PathwayBrowser/#/R-SSC-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-2509816 https://reactome.org/PathwayBrowser/#/R-SSC-2509816 NUDT16 hydrolyses IDP to IMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2509827 https://reactome.org/PathwayBrowser/#/R-SSC-2509827 ITPA hydrolyses ITP to IMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2509831 https://reactome.org/PathwayBrowser/#/R-SSC-2509831 ITPA hydrolyses XTP to XMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2509838 https://reactome.org/PathwayBrowser/#/R-SSC-2509838 ITPA hydrolyses dITP to dIMP IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-2534378 https://reactome.org/PathwayBrowser/#/R-SSC-2534378 Hv1 Mediated H+ Permeability IEA Sus scrofa 15378 R-ALL-1132304 H+ [cytoplasm] R-SSC-2534378 https://reactome.org/PathwayBrowser/#/R-SSC-2534378 Hv1 Mediated H+ Permeability IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-SSC-264615 https://reactome.org/PathwayBrowser/#/R-SSC-264615 Loading of acetylcholine in synaptic vesicles IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-266070 https://reactome.org/PathwayBrowser/#/R-SSC-266070 LTC4 is exported from the cytosol by ABCC1 IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-2671885 https://reactome.org/PathwayBrowser/#/R-SSC-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2730692 https://reactome.org/PathwayBrowser/#/R-SSC-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Sus scrofa 15378 R-ALL-74722 H+ [endosome lumen] R-SSC-2730692 https://reactome.org/PathwayBrowser/#/R-SSC-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2730959 https://reactome.org/PathwayBrowser/#/R-SSC-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-2730959 https://reactome.org/PathwayBrowser/#/R-SSC-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2855252 https://reactome.org/PathwayBrowser/#/R-SSC-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-2872444 https://reactome.org/PathwayBrowser/#/R-SSC-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-2872444 https://reactome.org/PathwayBrowser/#/R-SSC-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-2889070 https://reactome.org/PathwayBrowser/#/R-SSC-2889070 SLC9B2 exchanges Na+ for H+ IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-2889070 https://reactome.org/PathwayBrowser/#/R-SSC-2889070 SLC9B2 exchanges Na+ for H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3095889 https://reactome.org/PathwayBrowser/#/R-SSC-3095889 MMACHC dealkylates RCbl IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3149518 https://reactome.org/PathwayBrowser/#/R-SSC-3149518 MTRR reduces cob(II)alamin to meCbl IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3149519 https://reactome.org/PathwayBrowser/#/R-SSC-3149519 MMACHC decyanates CNCbl IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-3159253 https://reactome.org/PathwayBrowser/#/R-SSC-3159253 MMAB adenosylates cob(I)alamin IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-3299680 https://reactome.org/PathwayBrowser/#/R-SSC-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-3299682 https://reactome.org/PathwayBrowser/#/R-SSC-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3299691 https://reactome.org/PathwayBrowser/#/R-SSC-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322001 https://reactome.org/PathwayBrowser/#/R-SSC-3322001 GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322003 https://reactome.org/PathwayBrowser/#/R-SSC-3322003 Autoglucosylation of GYG1 complexed with GYS1-b IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322009 https://reactome.org/PathwayBrowser/#/R-SSC-3322009 GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322014 https://reactome.org/PathwayBrowser/#/R-SSC-3322014 Autoglucosylation of GYG2 complexed with GYS2-a IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322019 https://reactome.org/PathwayBrowser/#/R-SSC-3322019 Autoglucosylation of GYG2 complexed with GYS2-b IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322025 https://reactome.org/PathwayBrowser/#/R-SSC-3322025 Autoglucosylation of GYG1 complexed with GYS1-a IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3322041 https://reactome.org/PathwayBrowser/#/R-SSC-3322041 Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-3323079 https://reactome.org/PathwayBrowser/#/R-SSC-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-350869 https://reactome.org/PathwayBrowser/#/R-SSC-350869 Thyroxine is deiodinated to reverse triiodothyronine (RT3) IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-350901 https://reactome.org/PathwayBrowser/#/R-SSC-350901 Iodide is organified IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-352174 https://reactome.org/PathwayBrowser/#/R-SSC-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-352182 https://reactome.org/PathwayBrowser/#/R-SSC-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-372448 https://reactome.org/PathwayBrowser/#/R-SSC-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-373867 https://reactome.org/PathwayBrowser/#/R-SSC-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-373875 https://reactome.org/PathwayBrowser/#/R-SSC-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-375405 https://reactome.org/PathwayBrowser/#/R-SSC-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-375405 https://reactome.org/PathwayBrowser/#/R-SSC-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-375417 https://reactome.org/PathwayBrowser/#/R-SSC-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-3777112 https://reactome.org/PathwayBrowser/#/R-SSC-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3780994 https://reactome.org/PathwayBrowser/#/R-SSC-3780994 GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-3781024 https://reactome.org/PathwayBrowser/#/R-SSC-3781024 GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-379048 https://reactome.org/PathwayBrowser/#/R-SSC-379048 Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-380608 https://reactome.org/PathwayBrowser/#/R-SSC-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-389540 https://reactome.org/PathwayBrowser/#/R-SSC-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-389550 https://reactome.org/PathwayBrowser/#/R-SSC-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-389609 https://reactome.org/PathwayBrowser/#/R-SSC-389609 ALDH3A2-2 oxidizes pristanal to pristanate IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-389826 https://reactome.org/PathwayBrowser/#/R-SSC-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-390304 https://reactome.org/PathwayBrowser/#/R-SSC-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-390393 https://reactome.org/PathwayBrowser/#/R-SSC-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-390425 https://reactome.org/PathwayBrowser/#/R-SSC-390425 FAR1 reduces PalmCoA to HXOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-390438 https://reactome.org/PathwayBrowser/#/R-SSC-390438 FAR2 reduces PalmCoA to HXOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-418365 https://reactome.org/PathwayBrowser/#/R-SSC-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Sus scrofa 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-SSC-418365 https://reactome.org/PathwayBrowser/#/R-SSC-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-425577 https://reactome.org/PathwayBrowser/#/R-SSC-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-425965 https://reactome.org/PathwayBrowser/#/R-SSC-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Sus scrofa 15378 R-ALL-425999 H+ [late endosome lumen] R-SSC-425965 https://reactome.org/PathwayBrowser/#/R-SSC-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-425983 https://reactome.org/PathwayBrowser/#/R-SSC-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Sus scrofa 15378 R-ALL-425978 H+ [early endosome lumen] R-SSC-425983 https://reactome.org/PathwayBrowser/#/R-SSC-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-425994 https://reactome.org/PathwayBrowser/#/R-SSC-425994 Na+/H+ exchanger transport (at cell membrane) IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-425994 https://reactome.org/PathwayBrowser/#/R-SSC-425994 Na+/H+ exchanger transport (at cell membrane) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-426015 https://reactome.org/PathwayBrowser/#/R-SSC-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-426015 https://reactome.org/PathwayBrowser/#/R-SSC-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-426043 https://reactome.org/PathwayBrowser/#/R-SSC-426043 2-AG hydrolysis to arachidonate by MAGL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-427555 https://reactome.org/PathwayBrowser/#/R-SSC-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-427910 https://reactome.org/PathwayBrowser/#/R-SSC-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-427910 https://reactome.org/PathwayBrowser/#/R-SSC-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-427998 https://reactome.org/PathwayBrowser/#/R-SSC-427998 SLC25A1 transports di-/tri-peptides and peptide-like drugs IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-428007 https://reactome.org/PathwayBrowser/#/R-SSC-428007 Proton-coupled histidine and di-peptide cotransport IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-428015 https://reactome.org/PathwayBrowser/#/R-SSC-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428052 https://reactome.org/PathwayBrowser/#/R-SSC-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Sus scrofa 15378 R-ALL-428548 H+ [synaptic vesicle] R-SSC-428052 https://reactome.org/PathwayBrowser/#/R-SSC-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428123 https://reactome.org/PathwayBrowser/#/R-SSC-428123 KDSR reduces 3-ketosphingoid IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428127 https://reactome.org/PathwayBrowser/#/R-SSC-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428185 https://reactome.org/PathwayBrowser/#/R-SSC-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428259 https://reactome.org/PathwayBrowser/#/R-SSC-428259 DEGS1 dehydrogenates dihydroceramide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428260 https://reactome.org/PathwayBrowser/#/R-SSC-428260 DEGS2 oxygenates dihydroceramide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428273 https://reactome.org/PathwayBrowser/#/R-SSC-428273 SPHK1 phosphorylates sphingoid IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428585 https://reactome.org/PathwayBrowser/#/R-SSC-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-428585 https://reactome.org/PathwayBrowser/#/R-SSC-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-428625 https://reactome.org/PathwayBrowser/#/R-SSC-428625 Vesicular inhibitory amino acid transport IEA Sus scrofa 15378 R-ALL-428548 H+ [synaptic vesicle] R-SSC-428625 https://reactome.org/PathwayBrowser/#/R-SSC-428625 Vesicular inhibitory amino acid transport IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-429016 https://reactome.org/PathwayBrowser/#/R-SSC-429016 ALOX5 is phosphorylated by MAPKAP2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-429101 https://reactome.org/PathwayBrowser/#/R-SSC-429101 HMIT co-transports myo-inositol with a proton IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-429101 https://reactome.org/PathwayBrowser/#/R-SSC-429101 HMIT co-transports myo-inositol with a proton IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-429157 https://reactome.org/PathwayBrowser/#/R-SSC-429157 ABCC4 accumulation of dense granule contents IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-433698 https://reactome.org/PathwayBrowser/#/R-SSC-433698 SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-434650 https://reactome.org/PathwayBrowser/#/R-SSC-434650 MATEs mediate extrusion of xenobiotics IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-435171 https://reactome.org/PathwayBrowser/#/R-SSC-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-435349 https://reactome.org/PathwayBrowser/#/R-SSC-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-435349 https://reactome.org/PathwayBrowser/#/R-SSC-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-444393 https://reactome.org/PathwayBrowser/#/R-SSC-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-444393 https://reactome.org/PathwayBrowser/#/R-SSC-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-444419 https://reactome.org/PathwayBrowser/#/R-SSC-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-444419 https://reactome.org/PathwayBrowser/#/R-SSC-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-444731 https://reactome.org/PathwayBrowser/#/R-SSC-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-446195 https://reactome.org/PathwayBrowser/#/R-SSC-446195 DOLK phosphorylates DCHOL to DOLP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-446200 https://reactome.org/PathwayBrowser/#/R-SSC-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-446221 https://reactome.org/PathwayBrowser/#/R-SSC-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-446277 https://reactome.org/PathwayBrowser/#/R-SSC-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-446277 https://reactome.org/PathwayBrowser/#/R-SSC-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-446278 https://reactome.org/PathwayBrowser/#/R-SSC-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-446278 https://reactome.org/PathwayBrowser/#/R-SSC-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-469659 https://reactome.org/PathwayBrowser/#/R-SSC-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-504054 https://reactome.org/PathwayBrowser/#/R-SSC-504054 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-508040 https://reactome.org/PathwayBrowser/#/R-SSC-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-508308 https://reactome.org/PathwayBrowser/#/R-SSC-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-508369 https://reactome.org/PathwayBrowser/#/R-SSC-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-508473 https://reactome.org/PathwayBrowser/#/R-SSC-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-514604 https://reactome.org/PathwayBrowser/#/R-SSC-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5218841 https://reactome.org/PathwayBrowser/#/R-SSC-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5340130 https://reactome.org/PathwayBrowser/#/R-SSC-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-5340130 https://reactome.org/PathwayBrowser/#/R-SSC-5340130 CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5362518 https://reactome.org/PathwayBrowser/#/R-SSC-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5362522 https://reactome.org/PathwayBrowser/#/R-SSC-5362522 ALDHs oxidise atRAL to atRA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5362525 https://reactome.org/PathwayBrowser/#/R-SSC-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5362564 https://reactome.org/PathwayBrowser/#/R-SSC-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5362721 https://reactome.org/PathwayBrowser/#/R-SSC-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5419165 https://reactome.org/PathwayBrowser/#/R-SSC-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5423637 https://reactome.org/PathwayBrowser/#/R-SSC-5423637 AKR dimers reduce AFBDHO to AFBDOH IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5423647 https://reactome.org/PathwayBrowser/#/R-SSC-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5423664 https://reactome.org/PathwayBrowser/#/R-SSC-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5423672 https://reactome.org/PathwayBrowser/#/R-SSC-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5423678 https://reactome.org/PathwayBrowser/#/R-SSC-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-548800 https://reactome.org/PathwayBrowser/#/R-SSC-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-548814 https://reactome.org/PathwayBrowser/#/R-SSC-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-548815 https://reactome.org/PathwayBrowser/#/R-SSC-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-548818 https://reactome.org/PathwayBrowser/#/R-SSC-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-548831 https://reactome.org/PathwayBrowser/#/R-SSC-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5602295 https://reactome.org/PathwayBrowser/#/R-SSC-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5615668 https://reactome.org/PathwayBrowser/#/R-SSC-5615668 AKR1C3 reduces atRAL to atROL IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-5623643 https://reactome.org/PathwayBrowser/#/R-SSC-5623643 RDH13 reduces atRAL to atROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5652172 https://reactome.org/PathwayBrowser/#/R-SSC-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5652195 https://reactome.org/PathwayBrowser/#/R-SSC-5652195 SORD oxidizes D-sorbitol to Fru IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5661240 https://reactome.org/PathwayBrowser/#/R-SSC-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5661256 https://reactome.org/PathwayBrowser/#/R-SSC-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5661290 https://reactome.org/PathwayBrowser/#/R-SSC-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5662471 https://reactome.org/PathwayBrowser/#/R-SSC-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Sus scrofa 15378 R-ALL-5668577 H+ [melanosome lumen] R-SSC-5662662 https://reactome.org/PathwayBrowser/#/R-SSC-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5668629 https://reactome.org/PathwayBrowser/#/R-SSC-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5668718 https://reactome.org/PathwayBrowser/#/R-SSC-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5668731 https://reactome.org/PathwayBrowser/#/R-SSC-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5678327 https://reactome.org/PathwayBrowser/#/R-SSC-5678327 MIOX oxidises Ins to GlcA IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-5690042 https://reactome.org/PathwayBrowser/#/R-SSC-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-5690046 https://reactome.org/PathwayBrowser/#/R-SSC-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Sus scrofa 15378 R-ALL-428040 H+ [lysosomal lumen] R-SSC-5690517 https://reactome.org/PathwayBrowser/#/R-SSC-5690517 PPT1 hydrolyses palmitoylated proteins IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5690565 https://reactome.org/PathwayBrowser/#/R-SSC-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-5691107 https://reactome.org/PathwayBrowser/#/R-SSC-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5692237 https://reactome.org/PathwayBrowser/#/R-SSC-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5692261 https://reactome.org/PathwayBrowser/#/R-SSC-5692261 ALDH3A2-1 oxidises HD2NAL to PALM IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5692283 https://reactome.org/PathwayBrowser/#/R-SSC-5692283 ALD3A1 oxidises 4HPCP to CXPA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-5693148 https://reactome.org/PathwayBrowser/#/R-SSC-5693148 BCKDK phosphorylates BCKDH IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-5693347 https://reactome.org/PathwayBrowser/#/R-SSC-5693347 CRYM reduces P2C to PPCA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5693390 https://reactome.org/PathwayBrowser/#/R-SSC-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-5693681 https://reactome.org/PathwayBrowser/#/R-SSC-5693681 DUOX1,2 reduce O2 to H2O2 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-5693691 https://reactome.org/PathwayBrowser/#/R-SSC-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5693761 https://reactome.org/PathwayBrowser/#/R-SSC-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-5693967 https://reactome.org/PathwayBrowser/#/R-SSC-5693967 PXLP-K754-GLDC dimer decarboxylates Gly IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-5694018 https://reactome.org/PathwayBrowser/#/R-SSC-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5694462 https://reactome.org/PathwayBrowser/#/R-SSC-5694462 ABHD6,12 hydrolyse 3AG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5696021 https://reactome.org/PathwayBrowser/#/R-SSC-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5696080 https://reactome.org/PathwayBrowser/#/R-SSC-5696080 ALDH3B1 oxidises HXAL to PALM IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-5696091 https://reactome.org/PathwayBrowser/#/R-SSC-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5696101 https://reactome.org/PathwayBrowser/#/R-SSC-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-5696131 https://reactome.org/PathwayBrowser/#/R-SSC-5696131 AOC1 deaminates Hist IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-5696146 https://reactome.org/PathwayBrowser/#/R-SSC-5696146 AOC2 deaminates TYR IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-5696183 https://reactome.org/PathwayBrowser/#/R-SSC-5696183 AOC3 deaminates BZAM IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5696457 https://reactome.org/PathwayBrowser/#/R-SSC-5696457 BDH2 dehydrogenates 3HBA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-5696838 https://reactome.org/PathwayBrowser/#/R-SSC-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-597628 https://reactome.org/PathwayBrowser/#/R-SSC-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6783221 https://reactome.org/PathwayBrowser/#/R-SSC-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6783880 https://reactome.org/PathwayBrowser/#/R-SSC-6783880 PIPOX oxidises PPCA to P6C IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6783939 https://reactome.org/PathwayBrowser/#/R-SSC-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6783955 https://reactome.org/PathwayBrowser/#/R-SSC-6783955 PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6784224 https://reactome.org/PathwayBrowser/#/R-SSC-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6784402 https://reactome.org/PathwayBrowser/#/R-SSC-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-6785933 https://reactome.org/PathwayBrowser/#/R-SSC-6785933 UGT8 transfers Gal from UDP-Gal to CERA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6786239 https://reactome.org/PathwayBrowser/#/R-SSC-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6786245 https://reactome.org/PathwayBrowser/#/R-SSC-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6786720 https://reactome.org/PathwayBrowser/#/R-SSC-6786720 DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6787642 https://reactome.org/PathwayBrowser/#/R-SSC-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6787757 https://reactome.org/PathwayBrowser/#/R-SSC-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6788611 https://reactome.org/PathwayBrowser/#/R-SSC-6788611 HYKK phosphorylates 5HLYS IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6788999 https://reactome.org/PathwayBrowser/#/R-SSC-6788999 HV1-mediated H+ transfer IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-6788999 https://reactome.org/PathwayBrowser/#/R-SSC-6788999 HV1-mediated H+ transfer IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-6789031 https://reactome.org/PathwayBrowser/#/R-SSC-6789031 Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6789092 https://reactome.org/PathwayBrowser/#/R-SSC-6789092 NOX2 generates superoxide anion from oxygen IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-6789126 https://reactome.org/PathwayBrowser/#/R-SSC-6789126 Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6793590 https://reactome.org/PathwayBrowser/#/R-SSC-6793590 LIPT2 transfers octanoyl group to GCSH IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6793591 https://reactome.org/PathwayBrowser/#/R-SSC-6793591 LIAS synthesizes lipoyl-GCSH IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6798317 https://reactome.org/PathwayBrowser/#/R-SSC-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6798335 https://reactome.org/PathwayBrowser/#/R-SSC-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6799495 https://reactome.org/PathwayBrowser/#/R-SSC-6799495 GLYCTK phosphorylates DGA to 3PDGA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6799722 https://reactome.org/PathwayBrowser/#/R-SSC-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6801342 https://reactome.org/PathwayBrowser/#/R-SSC-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6803771 https://reactome.org/PathwayBrowser/#/R-SSC-6803771 NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-6806647 https://reactome.org/PathwayBrowser/#/R-SSC-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6806831 https://reactome.org/PathwayBrowser/#/R-SSC-6806831 CYB5Rs reduce MetHb to HbA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6806967 https://reactome.org/PathwayBrowser/#/R-SSC-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6807053 https://reactome.org/PathwayBrowser/#/R-SSC-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6807055 https://reactome.org/PathwayBrowser/#/R-SSC-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6807064 https://reactome.org/PathwayBrowser/#/R-SSC-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6807557 https://reactome.org/PathwayBrowser/#/R-SSC-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6808464 https://reactome.org/PathwayBrowser/#/R-SSC-6808464 ALDH3B2 oxidises HXAL to PALM IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-6808487 https://reactome.org/PathwayBrowser/#/R-SSC-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6808496 https://reactome.org/PathwayBrowser/#/R-SSC-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6809264 https://reactome.org/PathwayBrowser/#/R-SSC-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6809287 https://reactome.org/PathwayBrowser/#/R-SSC-6809287 NUDT12 hydrolyses NADH to NMNH IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6809810 https://reactome.org/PathwayBrowser/#/R-SSC-6809810 PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-6810474 https://reactome.org/PathwayBrowser/#/R-SSC-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6813749 https://reactome.org/PathwayBrowser/#/R-SSC-6813749 ALDH1A1 oxidises GA to DGA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6814153 https://reactome.org/PathwayBrowser/#/R-SSC-6814153 ADO oxidises 2AET to HTAU IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-6814165 https://reactome.org/PathwayBrowser/#/R-SSC-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70286 https://reactome.org/PathwayBrowser/#/R-SSC-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70333 https://reactome.org/PathwayBrowser/#/R-SSC-70333 KHK dimer phosphorylates Fru to Fru 1-P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70355 https://reactome.org/PathwayBrowser/#/R-SSC-70355 GALK1 phosphorylates Gal to Gal1P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70377 https://reactome.org/PathwayBrowser/#/R-SSC-70377 G6PD multimers dehydrogenate G6P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70420 https://reactome.org/PathwayBrowser/#/R-SSC-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70449 https://reactome.org/PathwayBrowser/#/R-SSC-70449 GADPH tetramer dehydrogenates GA3P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70467 https://reactome.org/PathwayBrowser/#/R-SSC-70467 PFK tetramer phosphorylates Fru(6)P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70482 https://reactome.org/PathwayBrowser/#/R-SSC-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70501 https://reactome.org/PathwayBrowser/#/R-SSC-70501 PC carboxylates PYR to OA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70510 https://reactome.org/PathwayBrowser/#/R-SSC-70510 LDH tetramer oxidises LACT to PYR IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70589 https://reactome.org/PathwayBrowser/#/R-SSC-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70599 https://reactome.org/PathwayBrowser/#/R-SSC-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70600 https://reactome.org/PathwayBrowser/#/R-SSC-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-70606 https://reactome.org/PathwayBrowser/#/R-SSC-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70664 https://reactome.org/PathwayBrowser/#/R-SSC-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70670 https://reactome.org/PathwayBrowser/#/R-SSC-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70679 https://reactome.org/PathwayBrowser/#/R-SSC-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70745 https://reactome.org/PathwayBrowser/#/R-SSC-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70773 https://reactome.org/PathwayBrowser/#/R-SSC-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70800 https://reactome.org/PathwayBrowser/#/R-SSC-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70837 https://reactome.org/PathwayBrowser/#/R-SSC-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70859 https://reactome.org/PathwayBrowser/#/R-SSC-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70881 https://reactome.org/PathwayBrowser/#/R-SSC-70881 beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70885 https://reactome.org/PathwayBrowser/#/R-SSC-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70893 https://reactome.org/PathwayBrowser/#/R-SSC-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70938 https://reactome.org/PathwayBrowser/#/R-SSC-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70940 https://reactome.org/PathwayBrowser/#/R-SSC-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70941 https://reactome.org/PathwayBrowser/#/R-SSC-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70975 https://reactome.org/PathwayBrowser/#/R-SSC-70975 CS acetylates OA to citrate IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-70979 https://reactome.org/PathwayBrowser/#/R-SSC-70979 MDH2 dimer dehydrogenates MAL IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-71046 https://reactome.org/PathwayBrowser/#/R-SSC-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71130 https://reactome.org/PathwayBrowser/#/R-SSC-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71164 https://reactome.org/PathwayBrowser/#/R-SSC-71164 HGD dioxygenates homogentisate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71181 https://reactome.org/PathwayBrowser/#/R-SSC-71181 FAH cleaves 4FAA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71200 https://reactome.org/PathwayBrowser/#/R-SSC-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71217 https://reactome.org/PathwayBrowser/#/R-SSC-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71260 https://reactome.org/PathwayBrowser/#/R-SSC-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71286 https://reactome.org/PathwayBrowser/#/R-SSC-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71296 https://reactome.org/PathwayBrowser/#/R-SSC-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-71401 https://reactome.org/PathwayBrowser/#/R-SSC-71401 OGDH dimer decarboxylates 2-OG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71541 https://reactome.org/PathwayBrowser/#/R-SSC-71541 glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71588 https://reactome.org/PathwayBrowser/#/R-SSC-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71670 https://reactome.org/PathwayBrowser/#/R-SSC-71670 PKM dephosphorylates PEP to PYR IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71682 https://reactome.org/PathwayBrowser/#/R-SSC-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71691 https://reactome.org/PathwayBrowser/#/R-SSC-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71707 https://reactome.org/PathwayBrowser/#/R-SSC-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-71723 https://reactome.org/PathwayBrowser/#/R-SSC-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71802 https://reactome.org/PathwayBrowser/#/R-SSC-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-71849 https://reactome.org/PathwayBrowser/#/R-SSC-71849 LDH tetramer reduces PYR to LACT IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73564 https://reactome.org/PathwayBrowser/#/R-SSC-73564 UMPS dimer decarboxylates OMP to UMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73571 https://reactome.org/PathwayBrowser/#/R-SSC-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73573 https://reactome.org/PathwayBrowser/#/R-SSC-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73577 https://reactome.org/PathwayBrowser/#/R-SSC-73577 CAD hexamer transforms L-Gln to CAP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73580 https://reactome.org/PathwayBrowser/#/R-SSC-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73585 https://reactome.org/PathwayBrowser/#/R-SSC-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73589 https://reactome.org/PathwayBrowser/#/R-SSC-73589 5,6-dihydrouracil + H2O => beta-ureidopropionate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73591 https://reactome.org/PathwayBrowser/#/R-SSC-73591 beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73596 https://reactome.org/PathwayBrowser/#/R-SSC-73596 dCMP + H2O => dUMP + NH4+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73616 https://reactome.org/PathwayBrowser/#/R-SSC-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73618 https://reactome.org/PathwayBrowser/#/R-SSC-73618 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73620 https://reactome.org/PathwayBrowser/#/R-SSC-73620 beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73647 https://reactome.org/PathwayBrowser/#/R-SSC-73647 UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-73666 https://reactome.org/PathwayBrowser/#/R-SSC-73666 dUTP + H2O => dUMP + pyrophosphate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73792 https://reactome.org/PathwayBrowser/#/R-SSC-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73794 https://reactome.org/PathwayBrowser/#/R-SSC-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73805 https://reactome.org/PathwayBrowser/#/R-SSC-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73806 https://reactome.org/PathwayBrowser/#/R-SSC-73806 AIR + CO2 => CAIR IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73810 https://reactome.org/PathwayBrowser/#/R-SSC-73810 FGAM + ATP => AIR + ADP + Pi IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73813 https://reactome.org/PathwayBrowser/#/R-SSC-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-73814 https://reactome.org/PathwayBrowser/#/R-SSC-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-73912 https://reactome.org/PathwayBrowser/#/R-SSC-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-73920 https://reactome.org/PathwayBrowser/#/R-SSC-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-74255 https://reactome.org/PathwayBrowser/#/R-SSC-74255 Guanine + H2O => Xanthine + NH4+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa 15378 R-ALL-74722 H+ [endosome lumen] R-SSC-74723 https://reactome.org/PathwayBrowser/#/R-SSC-74723 Endosome acidification IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-74872 https://reactome.org/PathwayBrowser/#/R-SSC-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-749448 https://reactome.org/PathwayBrowser/#/R-SSC-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-749452 https://reactome.org/PathwayBrowser/#/R-SSC-749452 The Ligand:GPCR:Gq complex dissociates IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-75851 https://reactome.org/PathwayBrowser/#/R-SSC-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-75872 https://reactome.org/PathwayBrowser/#/R-SSC-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-75883 https://reactome.org/PathwayBrowser/#/R-SSC-75883 DHRS7B reduces GO3P to HXDG3P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-75889 https://reactome.org/PathwayBrowser/#/R-SSC-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76354 https://reactome.org/PathwayBrowser/#/R-SSC-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76373 https://reactome.org/PathwayBrowser/#/R-SSC-76373 N-hydroxylation of 4-aminobiphenyl IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76386 https://reactome.org/PathwayBrowser/#/R-SSC-76386 CYP1A2 S-demethylates 6MMP IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76416 https://reactome.org/PathwayBrowser/#/R-SSC-76416 Benzene is hydroxylated to phenol IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76426 https://reactome.org/PathwayBrowser/#/R-SSC-76426 N-atom dealkylation of caffeine IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76453 https://reactome.org/PathwayBrowser/#/R-SSC-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76456 https://reactome.org/PathwayBrowser/#/R-SSC-76456 O-atom dealkylation of dextromethorphan IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76466 https://reactome.org/PathwayBrowser/#/R-SSC-76466 CYP4A11 12-hydroxylates DDCX IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76472 https://reactome.org/PathwayBrowser/#/R-SSC-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-76475 https://reactome.org/PathwayBrowser/#/R-SSC-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77254 https://reactome.org/PathwayBrowser/#/R-SSC-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77283 https://reactome.org/PathwayBrowser/#/R-SSC-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77303 https://reactome.org/PathwayBrowser/#/R-SSC-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77312 https://reactome.org/PathwayBrowser/#/R-SSC-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77323 https://reactome.org/PathwayBrowser/#/R-SSC-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77331 https://reactome.org/PathwayBrowser/#/R-SSC-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-77342 https://reactome.org/PathwayBrowser/#/R-SSC-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-804969 https://reactome.org/PathwayBrowser/#/R-SSC-804969 HSD17B1 hydrogenates E1 to EST17b IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8847579 https://reactome.org/PathwayBrowser/#/R-SSC-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8849638 https://reactome.org/PathwayBrowser/#/R-SSC-8849638 Dissociation of the SPINK5:KLK5 complex at low pH IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8850846 https://reactome.org/PathwayBrowser/#/R-SSC-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8850854 https://reactome.org/PathwayBrowser/#/R-SSC-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851089 https://reactome.org/PathwayBrowser/#/R-SSC-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851110 https://reactome.org/PathwayBrowser/#/R-SSC-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851129 https://reactome.org/PathwayBrowser/#/R-SSC-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-8851225 https://reactome.org/PathwayBrowser/#/R-SSC-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-8851234 https://reactome.org/PathwayBrowser/#/R-SSC-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851356 https://reactome.org/PathwayBrowser/#/R-SSC-8851356 NTPDase5 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851396 https://reactome.org/PathwayBrowser/#/R-SSC-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-SSC-8851494 https://reactome.org/PathwayBrowser/#/R-SSC-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851538 https://reactome.org/PathwayBrowser/#/R-SSC-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8851550 https://reactome.org/PathwayBrowser/#/R-SSC-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-8856223 https://reactome.org/PathwayBrowser/#/R-SSC-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8862137 https://reactome.org/PathwayBrowser/#/R-SSC-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-8862152 https://reactome.org/PathwayBrowser/#/R-SSC-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8863494 https://reactome.org/PathwayBrowser/#/R-SSC-8863494 ASICs bind STOML3, (STOM) IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-8863761 https://reactome.org/PathwayBrowser/#/R-SSC-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-8866601 https://reactome.org/PathwayBrowser/#/R-SSC-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8869606 https://reactome.org/PathwayBrowser/#/R-SSC-8869606 NMRK1 phosphorylates NAR to yield NAMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8869607 https://reactome.org/PathwayBrowser/#/R-SSC-8869607 NMRK2 phosphorylates NAR to yield NAMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8869627 https://reactome.org/PathwayBrowser/#/R-SSC-8869627 NMRK2 phosphorylates NR to yield NMN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8869633 https://reactome.org/PathwayBrowser/#/R-SSC-8869633 NMRK1 phosphorylates NR to yield NMN IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8870346 https://reactome.org/PathwayBrowser/#/R-SSC-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8875623 https://reactome.org/PathwayBrowser/#/R-SSC-8875623 SLC25A18,22 import L-Glu, H+ IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-8875623 https://reactome.org/PathwayBrowser/#/R-SSC-8875623 SLC25A18,22 import L-Glu, H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8876789 https://reactome.org/PathwayBrowser/#/R-SSC-8876789 CARNMT1 methylates CARN to Anserine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8876889 https://reactome.org/PathwayBrowser/#/R-SSC-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-8878914 https://reactome.org/PathwayBrowser/#/R-SSC-8878914 B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-888548 https://reactome.org/PathwayBrowser/#/R-SSC-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-888572 https://reactome.org/PathwayBrowser/#/R-SSC-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-888577 https://reactome.org/PathwayBrowser/#/R-SSC-888577 Synthesis of GABA by GAD2 IEA Sus scrofa 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-SSC-8933635 https://reactome.org/PathwayBrowser/#/R-SSC-8933635 Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8936442 https://reactome.org/PathwayBrowser/#/R-SSC-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8938076 https://reactome.org/PathwayBrowser/#/R-SSC-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8939959 https://reactome.org/PathwayBrowser/#/R-SSC-8939959 NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8940070 https://reactome.org/PathwayBrowser/#/R-SSC-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8942575 https://reactome.org/PathwayBrowser/#/R-SSC-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-8952873 https://reactome.org/PathwayBrowser/#/R-SSC-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-8954468 https://reactome.org/PathwayBrowser/#/R-SSC-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-8955030 https://reactome.org/PathwayBrowser/#/R-SSC-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8955760 https://reactome.org/PathwayBrowser/#/R-SSC-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8955844 https://reactome.org/PathwayBrowser/#/R-SSC-8955844 RBKS phosphorylates ribose to R5P IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-8956458 https://reactome.org/PathwayBrowser/#/R-SSC-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8959510 https://reactome.org/PathwayBrowser/#/R-SSC-8959510 SEPHS2 phosphorylates H2Se to form SELP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-8959719 https://reactome.org/PathwayBrowser/#/R-SSC-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9009950 https://reactome.org/PathwayBrowser/#/R-SSC-9009950 PDE12 cleaves 2'-5' oligoadenylates IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9011595 https://reactome.org/PathwayBrowser/#/R-SSC-9011595 GSTZ1 dimer dehalogenates DCA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9012016 https://reactome.org/PathwayBrowser/#/R-SSC-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9012036 https://reactome.org/PathwayBrowser/#/R-SSC-9012036 ME1 tetramer decarboxylates MAL to PYR IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-9013198 https://reactome.org/PathwayBrowser/#/R-SSC-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9024766 https://reactome.org/PathwayBrowser/#/R-SSC-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9027043 https://reactome.org/PathwayBrowser/#/R-SSC-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9027302 https://reactome.org/PathwayBrowser/#/R-SSC-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9027321 https://reactome.org/PathwayBrowser/#/R-SSC-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9037761 https://reactome.org/PathwayBrowser/#/R-SSC-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Sus scrofa 15378 R-ALL-74722 H+ [endosome lumen] R-SSC-917811 https://reactome.org/PathwayBrowser/#/R-SSC-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 15378 R-ALL-74722 H+ [endosome lumen] R-SSC-917841 https://reactome.org/PathwayBrowser/#/R-SSC-917841 Acidification of Tf:TfR1 containing endosome IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-917891 https://reactome.org/PathwayBrowser/#/R-SSC-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-917933 https://reactome.org/PathwayBrowser/#/R-SSC-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-917979 https://reactome.org/PathwayBrowser/#/R-SSC-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-937311 https://reactome.org/PathwayBrowser/#/R-SSC-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9619024 https://reactome.org/PathwayBrowser/#/R-SSC-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-9645220 https://reactome.org/PathwayBrowser/#/R-SSC-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-9650165 https://reactome.org/PathwayBrowser/#/R-SSC-9650165 ASIC trimers bind H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9695949 https://reactome.org/PathwayBrowser/#/R-SSC-9695949 SPHK2 phosphorylates sphingoid IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9705713 https://reactome.org/PathwayBrowser/#/R-SSC-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9705714 https://reactome.org/PathwayBrowser/#/R-SSC-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9709098 https://reactome.org/PathwayBrowser/#/R-SSC-9709098 DHFR dimer reduces FOLA to DHF IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-ALL-351626 H+ [extracellular region] R-SSC-9727198 https://reactome.org/PathwayBrowser/#/R-SSC-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9727347 https://reactome.org/PathwayBrowser/#/R-SSC-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9727349 https://reactome.org/PathwayBrowser/#/R-SSC-9727349 XDH dehydrogenates xanthine to form urate IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9731228 https://reactome.org/PathwayBrowser/#/R-SSC-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9731590 https://reactome.org/PathwayBrowser/#/R-SSC-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9731613 https://reactome.org/PathwayBrowser/#/R-SSC-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9731632 https://reactome.org/PathwayBrowser/#/R-SSC-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9731661 https://reactome.org/PathwayBrowser/#/R-SSC-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9748945 https://reactome.org/PathwayBrowser/#/R-SSC-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9748957 https://reactome.org/PathwayBrowser/#/R-SSC-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9748979 https://reactome.org/PathwayBrowser/#/R-SSC-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9748983 https://reactome.org/PathwayBrowser/#/R-SSC-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9748991 https://reactome.org/PathwayBrowser/#/R-SSC-9748991 XDH oxidises 6MP to 6TU IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9749792 https://reactome.org/PathwayBrowser/#/R-SSC-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9753285 https://reactome.org/PathwayBrowser/#/R-SSC-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9755937 https://reactome.org/PathwayBrowser/#/R-SSC-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756134 https://reactome.org/PathwayBrowser/#/R-SSC-9756134 UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756138 https://reactome.org/PathwayBrowser/#/R-SSC-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756156 https://reactome.org/PathwayBrowser/#/R-SSC-9756156 UGT1A3 lactonizes ATV to ATVL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756162 https://reactome.org/PathwayBrowser/#/R-SSC-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756169 https://reactome.org/PathwayBrowser/#/R-SSC-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756177 https://reactome.org/PathwayBrowser/#/R-SSC-9756177 PON1,3 hydrolyse ATVL to ATV IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756180 https://reactome.org/PathwayBrowser/#/R-SSC-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9756183 https://reactome.org/PathwayBrowser/#/R-SSC-9756183 UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-975629 https://reactome.org/PathwayBrowser/#/R-SSC-975629 RDH11 reduces RBP2:atRAL to RBP2:atROL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9757706 https://reactome.org/PathwayBrowser/#/R-SSC-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9758661 https://reactome.org/PathwayBrowser/#/R-SSC-9758661 UGT2B7,2B17,1A3 glucuronidates PRED metabolites IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9758674 https://reactome.org/PathwayBrowser/#/R-SSC-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9758682 https://reactome.org/PathwayBrowser/#/R-SSC-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9759259 https://reactome.org/PathwayBrowser/#/R-SSC-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9759549 https://reactome.org/PathwayBrowser/#/R-SSC-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9760094 https://reactome.org/PathwayBrowser/#/R-SSC-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-977301 https://reactome.org/PathwayBrowser/#/R-SSC-977301 Histidine is decarboxylated to histamine IEA Sus scrofa 15378 R-ALL-193465 H+ [peroxisomal matrix] R-SSC-977317 https://reactome.org/PathwayBrowser/#/R-SSC-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-977348 https://reactome.org/PathwayBrowser/#/R-SSC-977348 PHGDH tetramer dehydrogenates 3PG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9773976 https://reactome.org/PathwayBrowser/#/R-SSC-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9794270 https://reactome.org/PathwayBrowser/#/R-SSC-9794270 SLCO1A2 transports Cipro(1+) into the cytosol IEA Sus scrofa 15378 R-ALL-9668967 H+ [nucleoplasm] R-SSC-9825790 https://reactome.org/PathwayBrowser/#/R-SSC-9825790 p-S207 KARS1 dimer synthesizes A(5')p4(5')A IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9837337 https://reactome.org/PathwayBrowser/#/R-SSC-9837337 DCAKD phosphorylates DP-CoA IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9843721 https://reactome.org/PathwayBrowser/#/R-SSC-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9844587 https://reactome.org/PathwayBrowser/#/R-SSC-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9844860 https://reactome.org/PathwayBrowser/#/R-SSC-9844860 ST3GAL5 transfers NeuNAc to ceramides IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9845516 https://reactome.org/PathwayBrowser/#/R-SSC-9845516 B3GALT4 transfers Gal to gangliosides IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9845538 https://reactome.org/PathwayBrowser/#/R-SSC-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9845587 https://reactome.org/PathwayBrowser/#/R-SSC-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9846305 https://reactome.org/PathwayBrowser/#/R-SSC-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9846332 https://reactome.org/PathwayBrowser/#/R-SSC-9846332 FUT1,2 transfer fucose to gangliosides IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9846477 https://reactome.org/PathwayBrowser/#/R-SSC-9846477 A4GALT transfers galactose to LacCer IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9846501 https://reactome.org/PathwayBrowser/#/R-SSC-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Sus scrofa 15378 R-ALL-425969 H+ [Golgi lumen] R-SSC-9851347 https://reactome.org/PathwayBrowser/#/R-SSC-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9853499 https://reactome.org/PathwayBrowser/#/R-SSC-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9854315 https://reactome.org/PathwayBrowser/#/R-SSC-9854315 CSKMT methylates Citrate Synthase IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9854415 https://reactome.org/PathwayBrowser/#/R-SSC-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9856871 https://reactome.org/PathwayBrowser/#/R-SSC-9856871 MDH1 reduces OA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9858321 https://reactome.org/PathwayBrowser/#/R-SSC-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9858589 https://reactome.org/PathwayBrowser/#/R-SSC-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9858590 https://reactome.org/PathwayBrowser/#/R-SSC-9858590 DLST transfers glutaryl to CoA IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9859148 https://reactome.org/PathwayBrowser/#/R-SSC-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9859172 https://reactome.org/PathwayBrowser/#/R-SSC-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9861616 https://reactome.org/PathwayBrowser/#/R-SSC-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9861642 https://reactome.org/PathwayBrowser/#/R-SSC-9861642 NEK1 phosphorylates ME1 IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9861660 https://reactome.org/PathwayBrowser/#/R-SSC-9861660 ME1 tetramer decarboxylates OA to PYR IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9861734 https://reactome.org/PathwayBrowser/#/R-SSC-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9864415 https://reactome.org/PathwayBrowser/#/R-SSC-9864415 AAC1 imports a proton IEA Sus scrofa 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-SSC-9864415 https://reactome.org/PathwayBrowser/#/R-SSC-9864415 AAC1 imports a proton IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9909159 https://reactome.org/PathwayBrowser/#/R-SSC-9909159 HK1 phosphorylates Mannose to Man6P IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9915971 https://reactome.org/PathwayBrowser/#/R-SSC-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9915992 https://reactome.org/PathwayBrowser/#/R-SSC-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9915993 https://reactome.org/PathwayBrowser/#/R-SSC-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9915997 https://reactome.org/PathwayBrowser/#/R-SSC-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-SSC-9929439 https://reactome.org/PathwayBrowser/#/R-SSC-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9935449 https://reactome.org/PathwayBrowser/#/R-SSC-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Sus scrofa 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-SSC-9935469 https://reactome.org/PathwayBrowser/#/R-SSC-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9937295 https://reactome.org/PathwayBrowser/#/R-SSC-9937295 SRD5A3 reduces polyprenal to dolichal IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9937298 https://reactome.org/PathwayBrowser/#/R-SSC-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Sus scrofa 15378 R-ALL-70106 H+ [cytosol] R-SSC-9937340 https://reactome.org/PathwayBrowser/#/R-SSC-9937340 DHRSX reduces dolichal to dolichol IEA Sus scrofa 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-109343 https://reactome.org/PathwayBrowser/#/R-XTR-109343 Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-111215 https://reactome.org/PathwayBrowser/#/R-XTR-111215 PRPS1 dimer pyrophosphorylates R5P using dATP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-111524 https://reactome.org/PathwayBrowser/#/R-XTR-111524 IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-111883 https://reactome.org/PathwayBrowser/#/R-XTR-111883 PLA2G4A (cPLA2) hydrolyzes phosphatidylcholine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1222376 https://reactome.org/PathwayBrowser/#/R-XTR-1222376 NOX2 generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1222516 https://reactome.org/PathwayBrowser/#/R-XTR-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Xenopus tropicalis 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-XTR-1222516 https://reactome.org/PathwayBrowser/#/R-XTR-1222516 Intraphagosomal pH is lowered to 5 by V-ATPase IEA Xenopus tropicalis 15378 R-ALL-2000349 H+ [phagolysosome] R-XTR-1236967 https://reactome.org/PathwayBrowser/#/R-XTR-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-1237047 https://reactome.org/PathwayBrowser/#/R-XTR-1237047 CA4:Zn2+ hydrates CO2 to HCO3- IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-1237059 https://reactome.org/PathwayBrowser/#/R-XTR-1237059 CA4:Zn2+ dehydrates HCO3- to CO2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1237119 https://reactome.org/PathwayBrowser/#/R-XTR-1237119 Acireductone is oxidized to MOB IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1237325 https://reactome.org/PathwayBrowser/#/R-XTR-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1247668 https://reactome.org/PathwayBrowser/#/R-XTR-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-139970 https://reactome.org/PathwayBrowser/#/R-XTR-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-143468 https://reactome.org/PathwayBrowser/#/R-XTR-143468 MEOS oxidizes ethanol to acetaldehyde IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-1475017 https://reactome.org/PathwayBrowser/#/R-XTR-1475017 Carbonic anhydrase dehydrates bicarbonate (plasma membrane) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1475022 https://reactome.org/PathwayBrowser/#/R-XTR-1475022 Carbonic anhydrase dehydrates bicarbonate (cytosol) IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-1475025 https://reactome.org/PathwayBrowser/#/R-XTR-1475025 Carbonic anhydrase hydrates carbon dioxide (plasma membrane) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1475026 https://reactome.org/PathwayBrowser/#/R-XTR-1475026 Carbonic anhydrase hydrates carbon dioxide (cytosol) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-1475028 https://reactome.org/PathwayBrowser/#/R-XTR-1475028 Carbonic anhydrase dehydrates bicarbonate (mitochondria) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-1475032 https://reactome.org/PathwayBrowser/#/R-XTR-1475032 Carbonic anhydrase hydrates carbon dioxide (mitochondria) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1475435 https://reactome.org/PathwayBrowser/#/R-XTR-1475435 CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1475436 https://reactome.org/PathwayBrowser/#/R-XTR-1475436 CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1497869 https://reactome.org/PathwayBrowser/#/R-XTR-1497869 Salvage - Sepiapterin is reduced to q-BH2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1562626 https://reactome.org/PathwayBrowser/#/R-XTR-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-156526 https://reactome.org/PathwayBrowser/#/R-XTR-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-158609 https://reactome.org/PathwayBrowser/#/R-XTR-158609 TPMT transfers CH3 from AdoMet to 6MP IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-159790 https://reactome.org/PathwayBrowser/#/R-XTR-159790 VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-1605797 https://reactome.org/PathwayBrowser/#/R-XTR-1605797 SMPD1 hydrolyzes SPHM IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1606273 https://reactome.org/PathwayBrowser/#/R-XTR-1606273 SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-1614362 https://reactome.org/PathwayBrowser/#/R-XTR-1614362 SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1614567 https://reactome.org/PathwayBrowser/#/R-XTR-1614567 Excess homocysteine yields homolanthionine and H2S IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1614591 https://reactome.org/PathwayBrowser/#/R-XTR-1614591 Excess cysteine yields lanthionine and H2S IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-1614605 https://reactome.org/PathwayBrowser/#/R-XTR-1614605 Persulfide sulfur is dioxygenated IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1614614 https://reactome.org/PathwayBrowser/#/R-XTR-1614614 Cysteine is degraded to pyruvate and H2S IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1614631 https://reactome.org/PathwayBrowser/#/R-XTR-1614631 Homocysteine is degraded to oxobutanoate and H2S IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1614645 https://reactome.org/PathwayBrowser/#/R-XTR-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-162730 https://reactome.org/PathwayBrowser/#/R-XTR-162730 phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-163214 https://reactome.org/PathwayBrowser/#/R-XTR-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-163217 https://reactome.org/PathwayBrowser/#/R-XTR-163217 Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-1638104 https://reactome.org/PathwayBrowser/#/R-XTR-1638104 UGCG transfers glucose to ceramide IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1638845 https://reactome.org/PathwayBrowser/#/R-XTR-1638845 CERK phosphorylates CERA to form C1P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1640164 https://reactome.org/PathwayBrowser/#/R-XTR-1640164 ENPP7 hydrolyzes sphingomyelin IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-1655453 https://reactome.org/PathwayBrowser/#/R-XTR-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-1655879 https://reactome.org/PathwayBrowser/#/R-XTR-1655879 Thiosulfate can transfer its sulfur atom to glutathione IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-169270 https://reactome.org/PathwayBrowser/#/R-XTR-169270 ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 UCP1 imports a proton IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-170026 https://reactome.org/PathwayBrowser/#/R-XTR-170026 UCP1 imports a proton IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-173597 https://reactome.org/PathwayBrowser/#/R-XTR-173597 UDP-glucose is oxidised to UDP-glucuronate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-174389 https://reactome.org/PathwayBrowser/#/R-XTR-174389 PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-174392 https://reactome.org/PathwayBrowser/#/R-XTR-174392 PAPSS1,2 transfer SO4(2-) group to ATP to form APS IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-189421 https://reactome.org/PathwayBrowser/#/R-XTR-189421 CPO transforms COPRO3 to PPGEN9 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-189425 https://reactome.org/PathwayBrowser/#/R-XTR-189425 UROD decarboxylates URO3 to COPRO3 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-189439 https://reactome.org/PathwayBrowser/#/R-XTR-189439 ALAD condenses 2 dALAs to form PBG IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-189442 https://reactome.org/PathwayBrowser/#/R-XTR-189442 ALAS condenses SUCC-CoA and Gly to form dALA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-190182 https://reactome.org/PathwayBrowser/#/R-XTR-190182 UROD decarboxylates URO1 to COPRO1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-191299 https://reactome.org/PathwayBrowser/#/R-XTR-191299 Squalene is oxidized to its epoxide IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-191352 https://reactome.org/PathwayBrowser/#/R-XTR-191352 HMGCR dimer reduces bHMG-CoA to MVA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-191402 https://reactome.org/PathwayBrowser/#/R-XTR-191402 Reduction of presqualene diphosphate to form squalene IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-191972 https://reactome.org/PathwayBrowser/#/R-XTR-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-191983 https://reactome.org/PathwayBrowser/#/R-XTR-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192033 https://reactome.org/PathwayBrowser/#/R-XTR-192033 4-cholesten-7alpha-ol-3-one is reduced to 5beta-cholestan-7alpha-ol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192036 https://reactome.org/PathwayBrowser/#/R-XTR-192036 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192051 https://reactome.org/PathwayBrowser/#/R-XTR-192051 CYP7A1 7-hydroxylates CHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192061 https://reactome.org/PathwayBrowser/#/R-XTR-192061 CYP46A1 24-hydroxylates CHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192065 https://reactome.org/PathwayBrowser/#/R-XTR-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192067 https://reactome.org/PathwayBrowser/#/R-XTR-192067 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192097 https://reactome.org/PathwayBrowser/#/R-XTR-192097 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192157 https://reactome.org/PathwayBrowser/#/R-XTR-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192160 https://reactome.org/PathwayBrowser/#/R-XTR-192160 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-192178 https://reactome.org/PathwayBrowser/#/R-XTR-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193054 https://reactome.org/PathwayBrowser/#/R-XTR-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193060 https://reactome.org/PathwayBrowser/#/R-XTR-193060 CYP19A1 hydroxylates ANDST to E1 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193065 https://reactome.org/PathwayBrowser/#/R-XTR-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193068 https://reactome.org/PathwayBrowser/#/R-XTR-193068 CYP17A1 17-hydroxylates PREG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193070 https://reactome.org/PathwayBrowser/#/R-XTR-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193072 https://reactome.org/PathwayBrowser/#/R-XTR-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193099 https://reactome.org/PathwayBrowser/#/R-XTR-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193101 https://reactome.org/PathwayBrowser/#/R-XTR-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193143 https://reactome.org/PathwayBrowser/#/R-XTR-193143 CYP19A1 hydroxylates TEST to EST17b IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193709 https://reactome.org/PathwayBrowser/#/R-XTR-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193746 https://reactome.org/PathwayBrowser/#/R-XTR-193746 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193755 https://reactome.org/PathwayBrowser/#/R-XTR-193755 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193758 https://reactome.org/PathwayBrowser/#/R-XTR-193758 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193781 https://reactome.org/PathwayBrowser/#/R-XTR-193781 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193789 https://reactome.org/PathwayBrowser/#/R-XTR-193789 Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193800 https://reactome.org/PathwayBrowser/#/R-XTR-193800 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193816 https://reactome.org/PathwayBrowser/#/R-XTR-193816 Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193821 https://reactome.org/PathwayBrowser/#/R-XTR-193821 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193824 https://reactome.org/PathwayBrowser/#/R-XTR-193824 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193841 https://reactome.org/PathwayBrowser/#/R-XTR-193841 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-193845 https://reactome.org/PathwayBrowser/#/R-XTR-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193965 https://reactome.org/PathwayBrowser/#/R-XTR-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193995 https://reactome.org/PathwayBrowser/#/R-XTR-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-193997 https://reactome.org/PathwayBrowser/#/R-XTR-193997 CYP11B1 oxidises 11DCORT IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-194017 https://reactome.org/PathwayBrowser/#/R-XTR-194017 CYP11B2 oxidises 11DCORST to CORST IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-194023 https://reactome.org/PathwayBrowser/#/R-XTR-194023 HSD11B2,HSD11B1 dimer oxidise CORT to COR IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-194641 https://reactome.org/PathwayBrowser/#/R-XTR-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-194669 https://reactome.org/PathwayBrowser/#/R-XTR-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Xenopus tropicalis 15378 R-ALL-194688 H+ [nuclear envelope] R-XTR-194674 https://reactome.org/PathwayBrowser/#/R-XTR-194674 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-195664 https://reactome.org/PathwayBrowser/#/R-XTR-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196060 https://reactome.org/PathwayBrowser/#/R-XTR-196060 Reduction of isocaproaldehyde to 4-methylpentan-1-ol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196402 https://reactome.org/PathwayBrowser/#/R-XTR-196402 Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196417 https://reactome.org/PathwayBrowser/#/R-XTR-196417 Reduction of desmosterol to cholesterol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196753 https://reactome.org/PathwayBrowser/#/R-XTR-196753 2xPPCS ligates PPanK with Cys IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196754 https://reactome.org/PathwayBrowser/#/R-XTR-196754 COASY transfers an adenylyl group from ATP to PPANT IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196773 https://reactome.org/PathwayBrowser/#/R-XTR-196773 COASY phosphorylates DP-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196840 https://reactome.org/PathwayBrowser/#/R-XTR-196840 3xPPCDC:3FMN decarboxylates PPC IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196857 https://reactome.org/PathwayBrowser/#/R-XTR-196857 PANK2 phosphorylates PanK IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196955 https://reactome.org/PathwayBrowser/#/R-XTR-196955 2xENPP1 hydrolyzes FAD to FMN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-196964 https://reactome.org/PathwayBrowser/#/R-XTR-196964 RFK:Mg2+ phosphorylates RIB IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-197198 https://reactome.org/PathwayBrowser/#/R-XTR-197198 NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-197250 https://reactome.org/PathwayBrowser/#/R-XTR-197250 NAMPT transfers PRIB to NAM to form NAMN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-197268 https://reactome.org/PathwayBrowser/#/R-XTR-197268 QPRT transfers PRIB to QUIN to form NAMN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-198824 https://reactome.org/PathwayBrowser/#/R-XTR-198824 CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200555 https://reactome.org/PathwayBrowser/#/R-XTR-200555 Formation of Malonyl-CoA from Acetyl-CoA (liver) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200644 https://reactome.org/PathwayBrowser/#/R-XTR-200644 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200646 https://reactome.org/PathwayBrowser/#/R-XTR-200646 Cytosolic folate export across the plasma membrane IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-200646 https://reactome.org/PathwayBrowser/#/R-XTR-200646 Cytosolic folate export across the plasma membrane IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200676 https://reactome.org/PathwayBrowser/#/R-XTR-200676 MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200718 https://reactome.org/PathwayBrowser/#/R-XTR-200718 MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-200729 https://reactome.org/PathwayBrowser/#/R-XTR-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-200729 https://reactome.org/PathwayBrowser/#/R-XTR-200729 SLC46A1 transports FOLA from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-203946 https://reactome.org/PathwayBrowser/#/R-XTR-203946 PDK isozymes phosphorylate PDHC subunit E1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-204617 https://reactome.org/PathwayBrowser/#/R-XTR-204617 DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-204647 https://reactome.org/PathwayBrowser/#/R-XTR-204647 DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-204662 https://reactome.org/PathwayBrowser/#/R-XTR-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-209821 https://reactome.org/PathwayBrowser/#/R-XTR-209821 Methylation of N-acetyl-5-HT to form melatonin IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-209845 https://reactome.org/PathwayBrowser/#/R-XTR-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-210404 https://reactome.org/PathwayBrowser/#/R-XTR-210404 SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-211873 https://reactome.org/PathwayBrowser/#/R-XTR-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211874 https://reactome.org/PathwayBrowser/#/R-XTR-211874 CYP2S1 4-hydroxylates atRA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211881 https://reactome.org/PathwayBrowser/#/R-XTR-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211882 https://reactome.org/PathwayBrowser/#/R-XTR-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211904 https://reactome.org/PathwayBrowser/#/R-XTR-211904 CYP4F12 18-hydroxylates ARA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211919 https://reactome.org/PathwayBrowser/#/R-XTR-211919 CYP4F8 19-hydroxylates PGH2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-211923 https://reactome.org/PathwayBrowser/#/R-XTR-211923 CYP26C1 4-hydroxylates 9cRA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211924 https://reactome.org/PathwayBrowser/#/R-XTR-211924 CYP4B1 12-hydroxylates ARA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211948 https://reactome.org/PathwayBrowser/#/R-XTR-211948 CYP3A4 can N-demethylate loperamide IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211959 https://reactome.org/PathwayBrowser/#/R-XTR-211959 CYP3A43 6b-hydroxylates TEST IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211960 https://reactome.org/PathwayBrowser/#/R-XTR-211960 CYP2U1 19-hydroxylates ARA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211962 https://reactome.org/PathwayBrowser/#/R-XTR-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211966 https://reactome.org/PathwayBrowser/#/R-XTR-211966 CYP2D6 4-hydroxylates debrisoquine IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211968 https://reactome.org/PathwayBrowser/#/R-XTR-211968 CYP2W1 oxidises INDOL IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211983 https://reactome.org/PathwayBrowser/#/R-XTR-211983 CYP2J2 oxidises ARA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-211991 https://reactome.org/PathwayBrowser/#/R-XTR-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-212005 https://reactome.org/PathwayBrowser/#/R-XTR-212005 CYP2F1 dehydrogenates 3-methylindole IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-212007 https://reactome.org/PathwayBrowser/#/R-XTR-212007 CYP26A1,B1 4-hydroxylate atRA IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-213175 https://reactome.org/PathwayBrowser/#/R-XTR-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-215526 https://reactome.org/PathwayBrowser/#/R-XTR-215526 CYP4F3 20-hydroxylates LTB4 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161187 https://reactome.org/PathwayBrowser/#/R-XTR-2161187 ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161549 https://reactome.org/PathwayBrowser/#/R-XTR-2161549 PGH2 is reduced to PGF2a by AKR1C3 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161614 https://reactome.org/PathwayBrowser/#/R-XTR-2161614 PGD2 is reduced to 11-epi-PGF2a by AKRIC3 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161651 https://reactome.org/PathwayBrowser/#/R-XTR-2161651 PGE2 is converted to PGF2a by CBR1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161745 https://reactome.org/PathwayBrowser/#/R-XTR-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161779 https://reactome.org/PathwayBrowser/#/R-XTR-2161779 LXA4 is oxidised to 15k-LXA4 by HPGD IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161792 https://reactome.org/PathwayBrowser/#/R-XTR-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-2161814 https://reactome.org/PathwayBrowser/#/R-XTR-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161890 https://reactome.org/PathwayBrowser/#/R-XTR-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161899 https://reactome.org/PathwayBrowser/#/R-XTR-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-2161940 https://reactome.org/PathwayBrowser/#/R-XTR-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2161951 https://reactome.org/PathwayBrowser/#/R-XTR-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2162078 https://reactome.org/PathwayBrowser/#/R-XTR-2162078 abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162186 https://reactome.org/PathwayBrowser/#/R-XTR-2162186 COQ3 methylates DeMQ10H2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162187 https://reactome.org/PathwayBrowser/#/R-XTR-2162187 COQ6 hydroxylates DHB IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162188 https://reactome.org/PathwayBrowser/#/R-XTR-2162188 COQ5 methylates MDMQ10H2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162193 https://reactome.org/PathwayBrowser/#/R-XTR-2162193 COQ3 methylates DHDB IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162194 https://reactome.org/PathwayBrowser/#/R-XTR-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2162195 https://reactome.org/PathwayBrowser/#/R-XTR-2162195 COQ4 decarboxylates MHDB IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-217255 https://reactome.org/PathwayBrowser/#/R-XTR-217255 FMO1:FAD N-oxidises TAM IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-217258 https://reactome.org/PathwayBrowser/#/R-XTR-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2395512 https://reactome.org/PathwayBrowser/#/R-XTR-2395512 FDXR transfers electrons to FDX1,2 (FDX1L) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2395517 https://reactome.org/PathwayBrowser/#/R-XTR-2395517 NADPH transfers electrons to FDXR IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395818 https://reactome.org/PathwayBrowser/#/R-XTR-2395818 NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395849 https://reactome.org/PathwayBrowser/#/R-XTR-2395849 NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395869 https://reactome.org/PathwayBrowser/#/R-XTR-2395869 NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395872 https://reactome.org/PathwayBrowser/#/R-XTR-2395872 NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395873 https://reactome.org/PathwayBrowser/#/R-XTR-2395873 NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395876 https://reactome.org/PathwayBrowser/#/R-XTR-2395876 NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395879 https://reactome.org/PathwayBrowser/#/R-XTR-2395879 NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2395965 https://reactome.org/PathwayBrowser/#/R-XTR-2395965 NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2408524 https://reactome.org/PathwayBrowser/#/R-XTR-2408524 Sec is reduced to H2Se by PXLP-K259-SCLY dimer IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2453833 https://reactome.org/PathwayBrowser/#/R-XTR-2453833 RPE65 isomero-hydrolyses atREs to 11cROL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2454081 https://reactome.org/PathwayBrowser/#/R-XTR-2454081 RDH5 oxidises 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2465940 https://reactome.org/PathwayBrowser/#/R-XTR-2465940 atRAL is reduced to atROL IEA Xenopus tropicalis 15378 R-ALL-9668967 H+ [nucleoplasm] R-XTR-2509793 https://reactome.org/PathwayBrowser/#/R-XTR-2509793 NUDT16 hydrolyses dIDP to dIMP IEA Xenopus tropicalis 15378 R-ALL-9668967 H+ [nucleoplasm] R-XTR-2509816 https://reactome.org/PathwayBrowser/#/R-XTR-2509816 NUDT16 hydrolyses IDP to IMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2509827 https://reactome.org/PathwayBrowser/#/R-XTR-2509827 ITPA hydrolyses ITP to IMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2509831 https://reactome.org/PathwayBrowser/#/R-XTR-2509831 ITPA hydrolyses XTP to XMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2509838 https://reactome.org/PathwayBrowser/#/R-XTR-2509838 ITPA hydrolyses dITP to dIMP IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-2534378 https://reactome.org/PathwayBrowser/#/R-XTR-2534378 Hv1 Mediated H+ Permeability IEA Xenopus tropicalis 15378 R-ALL-1132304 H+ [cytoplasm] R-XTR-2534378 https://reactome.org/PathwayBrowser/#/R-XTR-2534378 Hv1 Mediated H+ Permeability IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15378 R-ALL-372511 H+ [clathrin-sculpted acetylcholine transport vesicle lumen] R-XTR-264615 https://reactome.org/PathwayBrowser/#/R-XTR-264615 Loading of acetylcholine in synaptic vesicles IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-266070 https://reactome.org/PathwayBrowser/#/R-XTR-266070 LTC4 is exported from the cytosol by ABCC1 IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-2671885 https://reactome.org/PathwayBrowser/#/R-XTR-2671885 ASIC trimers:H+ transport extracellular Na+ to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2730692 https://reactome.org/PathwayBrowser/#/R-XTR-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Xenopus tropicalis 15378 R-ALL-74722 H+ [endosome lumen] R-XTR-2730692 https://reactome.org/PathwayBrowser/#/R-XTR-2730692 CLCN4/5/6 exchange Cl- for H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2730959 https://reactome.org/PathwayBrowser/#/R-XTR-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-2730959 https://reactome.org/PathwayBrowser/#/R-XTR-2730959 CLCN7:OSTM1 exchanges Cl- for H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2855252 https://reactome.org/PathwayBrowser/#/R-XTR-2855252 AKRs reduce RBP2:atRAL to RBP2:atROL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-2872444 https://reactome.org/PathwayBrowser/#/R-XTR-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-2872444 https://reactome.org/PathwayBrowser/#/R-XTR-2872444 SLC9B1/C2 exchange Na+ for H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-2889070 https://reactome.org/PathwayBrowser/#/R-XTR-2889070 SLC9B2 exchanges Na+ for H+ IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-2889070 https://reactome.org/PathwayBrowser/#/R-XTR-2889070 SLC9B2 exchanges Na+ for H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-3095889 https://reactome.org/PathwayBrowser/#/R-XTR-3095889 MMACHC dealkylates RCbl IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-3149519 https://reactome.org/PathwayBrowser/#/R-XTR-3149519 MMACHC decyanates CNCbl IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-3159253 https://reactome.org/PathwayBrowser/#/R-XTR-3159253 MMAB adenosylates cob(I)alamin IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-3299680 https://reactome.org/PathwayBrowser/#/R-XTR-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-3299682 https://reactome.org/PathwayBrowser/#/R-XTR-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-3299691 https://reactome.org/PathwayBrowser/#/R-XTR-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-3323079 https://reactome.org/PathwayBrowser/#/R-XTR-3323079 GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-352174 https://reactome.org/PathwayBrowser/#/R-XTR-352174 SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-352182 https://reactome.org/PathwayBrowser/#/R-XTR-352182 SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-372448 https://reactome.org/PathwayBrowser/#/R-XTR-372448 SLC25A12,13 exchange L-Glu and L-Asp IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-373867 https://reactome.org/PathwayBrowser/#/R-XTR-373867 BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-373875 https://reactome.org/PathwayBrowser/#/R-XTR-373875 BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-375405 https://reactome.org/PathwayBrowser/#/R-XTR-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-375405 https://reactome.org/PathwayBrowser/#/R-XTR-375405 SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-375417 https://reactome.org/PathwayBrowser/#/R-XTR-375417 SLC36A1-mediated uptake of glycine, proline, and alanine IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-3777112 https://reactome.org/PathwayBrowser/#/R-XTR-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-380608 https://reactome.org/PathwayBrowser/#/R-XTR-380608 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-389540 https://reactome.org/PathwayBrowser/#/R-XTR-389540 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-389550 https://reactome.org/PathwayBrowser/#/R-XTR-389550 isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-389826 https://reactome.org/PathwayBrowser/#/R-XTR-389826 glyoxylate + NADPH + H+ => glycolate + NADP+ IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-390304 https://reactome.org/PathwayBrowser/#/R-XTR-390304 acetyl-CoA + H2O => acetate + CoASH + H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-390393 https://reactome.org/PathwayBrowser/#/R-XTR-390393 Peroxisomal uptake of very long-chain fatty acyl CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-418365 https://reactome.org/PathwayBrowser/#/R-XTR-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Xenopus tropicalis 15378 R-ALL-427899 H+ [platelet dense tubular network lumen] R-XTR-418365 https://reactome.org/PathwayBrowser/#/R-XTR-418365 ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-425577 https://reactome.org/PathwayBrowser/#/R-XTR-425577 Na+-driven Cl-/HCO3- exchanger transport IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-425965 https://reactome.org/PathwayBrowser/#/R-XTR-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Xenopus tropicalis 15378 R-ALL-425999 H+ [late endosome lumen] R-XTR-425965 https://reactome.org/PathwayBrowser/#/R-XTR-425965 SLC9A9 exchanges Na+ for H+ across the late endosome membrane IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-425983 https://reactome.org/PathwayBrowser/#/R-XTR-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Xenopus tropicalis 15378 R-ALL-425978 H+ [early endosome lumen] R-XTR-425983 https://reactome.org/PathwayBrowser/#/R-XTR-425983 SLC9A6,7 exchange Na+ for H+ across the early endosome membrane IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-425994 https://reactome.org/PathwayBrowser/#/R-XTR-425994 Na+/H+ exchanger transport (at cell membrane) IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-425994 https://reactome.org/PathwayBrowser/#/R-XTR-425994 Na+/H+ exchanger transport (at cell membrane) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-426015 https://reactome.org/PathwayBrowser/#/R-XTR-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-426015 https://reactome.org/PathwayBrowser/#/R-XTR-426015 Na+/H+ exchanger transport (at trans-golgi membrane) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-426043 https://reactome.org/PathwayBrowser/#/R-XTR-426043 2-AG hydrolysis to arachidonate by MAGL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-427555 https://reactome.org/PathwayBrowser/#/R-XTR-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-427555 https://reactome.org/PathwayBrowser/#/R-XTR-427555 SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-427910 https://reactome.org/PathwayBrowser/#/R-XTR-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-427910 https://reactome.org/PathwayBrowser/#/R-XTR-427910 ATP2A1-3 transport Ca2+ from cytosol to ER lumen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-428007 https://reactome.org/PathwayBrowser/#/R-XTR-428007 Proton-coupled histidine and di-peptide cotransport IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-428015 https://reactome.org/PathwayBrowser/#/R-XTR-428015 SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428052 https://reactome.org/PathwayBrowser/#/R-XTR-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Xenopus tropicalis 15378 R-ALL-428548 H+ [synaptic vesicle] R-XTR-428052 https://reactome.org/PathwayBrowser/#/R-XTR-428052 SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428123 https://reactome.org/PathwayBrowser/#/R-XTR-428123 KDSR reduces 3-ketosphingoid IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428127 https://reactome.org/PathwayBrowser/#/R-XTR-428127 SPTLC complexes transfer acyl-CoA onto serine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428185 https://reactome.org/PathwayBrowser/#/R-XTR-428185 Ceramide synthases transfer acyl-CoA onto sphingoid IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428259 https://reactome.org/PathwayBrowser/#/R-XTR-428259 DEGS1 dehydrogenates dihydroceramide IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428260 https://reactome.org/PathwayBrowser/#/R-XTR-428260 DEGS2 oxygenates dihydroceramide IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-428585 https://reactome.org/PathwayBrowser/#/R-XTR-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-428585 https://reactome.org/PathwayBrowser/#/R-XTR-428585 SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-429101 https://reactome.org/PathwayBrowser/#/R-XTR-429101 HMIT co-transports myo-inositol with a proton IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-429101 https://reactome.org/PathwayBrowser/#/R-XTR-429101 HMIT co-transports myo-inositol with a proton IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-434650 https://reactome.org/PathwayBrowser/#/R-XTR-434650 MATEs mediate extrusion of xenobiotics IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-XTR-435171 https://reactome.org/PathwayBrowser/#/R-XTR-435171 NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-435349 https://reactome.org/PathwayBrowser/#/R-XTR-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-435349 https://reactome.org/PathwayBrowser/#/R-XTR-435349 SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-444393 https://reactome.org/PathwayBrowser/#/R-XTR-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-444393 https://reactome.org/PathwayBrowser/#/R-XTR-444393 RhCG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-444419 https://reactome.org/PathwayBrowser/#/R-XTR-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-444419 https://reactome.org/PathwayBrowser/#/R-XTR-444419 RhBG mediates ammonium effflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-444731 https://reactome.org/PathwayBrowser/#/R-XTR-444731 GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-446195 https://reactome.org/PathwayBrowser/#/R-XTR-446195 DOLK phosphorylates DCHOL to DOLP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-446200 https://reactome.org/PathwayBrowser/#/R-XTR-446200 DOLPP1 dephosphorylates DOLDP to DOLP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-446221 https://reactome.org/PathwayBrowser/#/R-XTR-446221 GMPPB converts Mannose-1-phosphate to GDP-Mannose IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-446277 https://reactome.org/PathwayBrowser/#/R-XTR-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-446277 https://reactome.org/PathwayBrowser/#/R-XTR-446277 RhCG mediates ammonium efflux out of kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-446278 https://reactome.org/PathwayBrowser/#/R-XTR-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-446278 https://reactome.org/PathwayBrowser/#/R-XTR-446278 RhBG mediates ammonium influx into kidney collecting duct cells IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-450971 https://reactome.org/PathwayBrowser/#/R-XTR-450971 NNT dimer transfers proton from NADPH to NAD+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-469659 https://reactome.org/PathwayBrowser/#/R-XTR-469659 SRD5A1 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-508040 https://reactome.org/PathwayBrowser/#/R-XTR-508040 glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-508308 https://reactome.org/PathwayBrowser/#/R-XTR-508308 beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-508369 https://reactome.org/PathwayBrowser/#/R-XTR-508369 alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-508473 https://reactome.org/PathwayBrowser/#/R-XTR-508473 methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-514604 https://reactome.org/PathwayBrowser/#/R-XTR-514604 GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5218841 https://reactome.org/PathwayBrowser/#/R-XTR-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5362518 https://reactome.org/PathwayBrowser/#/R-XTR-5362518 RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5362522 https://reactome.org/PathwayBrowser/#/R-XTR-5362522 ALDHs oxidise atRAL to atRA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5362525 https://reactome.org/PathwayBrowser/#/R-XTR-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5362564 https://reactome.org/PathwayBrowser/#/R-XTR-5362564 ADH1A,1C,4 oxidise atROL to atRAL in vitro IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5362721 https://reactome.org/PathwayBrowser/#/R-XTR-5362721 RDH5,RDH11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5419165 https://reactome.org/PathwayBrowser/#/R-XTR-5419165 RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5423647 https://reactome.org/PathwayBrowser/#/R-XTR-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5423664 https://reactome.org/PathwayBrowser/#/R-XTR-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5423672 https://reactome.org/PathwayBrowser/#/R-XTR-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-548800 https://reactome.org/PathwayBrowser/#/R-XTR-548800 ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-548814 https://reactome.org/PathwayBrowser/#/R-XTR-548814 ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-548815 https://reactome.org/PathwayBrowser/#/R-XTR-548815 ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-548818 https://reactome.org/PathwayBrowser/#/R-XTR-548818 HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-548831 https://reactome.org/PathwayBrowser/#/R-XTR-548831 TECR,TECRL dehydrogenate TOD-CoA to ST-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5602295 https://reactome.org/PathwayBrowser/#/R-XTR-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5615668 https://reactome.org/PathwayBrowser/#/R-XTR-5615668 AKR1C3 reduces atRAL to atROL IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-5623643 https://reactome.org/PathwayBrowser/#/R-XTR-5623643 RDH13 reduces atRAL to atROL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5652172 https://reactome.org/PathwayBrowser/#/R-XTR-5652172 AKR1B1 reduces Glc to D-sorbitol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5652195 https://reactome.org/PathwayBrowser/#/R-XTR-5652195 SORD oxidizes D-sorbitol to Fru IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5661240 https://reactome.org/PathwayBrowser/#/R-XTR-5661240 DCXR tetramer reduces L-xylulose to xylitol IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5661256 https://reactome.org/PathwayBrowser/#/R-XTR-5661256 AKR1A1 reduces D-glucuronate to L-gulonate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5661290 https://reactome.org/PathwayBrowser/#/R-XTR-5661290 CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5662471 https://reactome.org/PathwayBrowser/#/R-XTR-5662471 SORD tetramer oxidizes xylitol to D-xylulose IEA Xenopus tropicalis 15378 R-ALL-5668577 H+ [melanosome lumen] R-XTR-5662662 https://reactome.org/PathwayBrowser/#/R-XTR-5662662 Tyrosinase oxidises tyrosine to dopaquinone IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5668629 https://reactome.org/PathwayBrowser/#/R-XTR-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5668718 https://reactome.org/PathwayBrowser/#/R-XTR-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5668731 https://reactome.org/PathwayBrowser/#/R-XTR-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-5690042 https://reactome.org/PathwayBrowser/#/R-XTR-5690042 Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-5690046 https://reactome.org/PathwayBrowser/#/R-XTR-5690046 PPT2 hydrolyses PALMCoA to PALM IEA Xenopus tropicalis 15378 R-ALL-428040 H+ [lysosomal lumen] R-XTR-5690517 https://reactome.org/PathwayBrowser/#/R-XTR-5690517 PPT1 hydrolyses palmitoylated proteins IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5690565 https://reactome.org/PathwayBrowser/#/R-XTR-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-5691107 https://reactome.org/PathwayBrowser/#/R-XTR-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5692237 https://reactome.org/PathwayBrowser/#/R-XTR-5692237 ADH5 oxidises S-HMGSH to S-FGSH IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-5693148 https://reactome.org/PathwayBrowser/#/R-XTR-5693148 BCKDK phosphorylates BCKDH IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-5693347 https://reactome.org/PathwayBrowser/#/R-XTR-5693347 CRYM reduces P2C to PPCA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5693390 https://reactome.org/PathwayBrowser/#/R-XTR-5693390 HSD17B11 dehydrogenates EST17b to E1 IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-5693681 https://reactome.org/PathwayBrowser/#/R-XTR-5693681 DUOX1,2 reduce O2 to H2O2 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-5693691 https://reactome.org/PathwayBrowser/#/R-XTR-5693691 CES1 trimer.CES2 hydrolyse COCN to BEG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5693761 https://reactome.org/PathwayBrowser/#/R-XTR-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-5694018 https://reactome.org/PathwayBrowser/#/R-XTR-5694018 DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5694462 https://reactome.org/PathwayBrowser/#/R-XTR-5694462 ABHD6,12 hydrolyse 3AG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5696021 https://reactome.org/PathwayBrowser/#/R-XTR-5696021 ADPGK:Mg2+ phosphorylates Glc to G6P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5696080 https://reactome.org/PathwayBrowser/#/R-XTR-5696080 ALDH3B1 oxidises HXAL to PALM IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-5696091 https://reactome.org/PathwayBrowser/#/R-XTR-5696091 ALDH1B1 tetramer oxidises CH3CHO to CH3COOH IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5696101 https://reactome.org/PathwayBrowser/#/R-XTR-5696101 ALDH8A1 oxidises 9cRAL to 9cRA IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-5696131 https://reactome.org/PathwayBrowser/#/R-XTR-5696131 AOC1 deaminates Hist IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-5696183 https://reactome.org/PathwayBrowser/#/R-XTR-5696183 AOC3 deaminates BZAM IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-5696822 https://reactome.org/PathwayBrowser/#/R-XTR-5696822 AKR1B15 reduces EST17b to E1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-5696838 https://reactome.org/PathwayBrowser/#/R-XTR-5696838 BHMT2 tetramer transfers CH3 group from SMM to LHCYS IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-597628 https://reactome.org/PathwayBrowser/#/R-XTR-597628 SLC22A18 exchanges extracellular organic cations for cytosolic H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6783221 https://reactome.org/PathwayBrowser/#/R-XTR-6783221 HAGH hydrolyses (R)-S-LGSH to GSH and LACT IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-6783880 https://reactome.org/PathwayBrowser/#/R-XTR-6783880 PIPOX oxidises PPCA to P6C IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6783939 https://reactome.org/PathwayBrowser/#/R-XTR-6783939 PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6784224 https://reactome.org/PathwayBrowser/#/R-XTR-6784224 PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6784402 https://reactome.org/PathwayBrowser/#/R-XTR-6784402 ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6786239 https://reactome.org/PathwayBrowser/#/R-XTR-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6786245 https://reactome.org/PathwayBrowser/#/R-XTR-6786245 CARNS1 transforms ATP, L-His, b-Ala to CARN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6787642 https://reactome.org/PathwayBrowser/#/R-XTR-6787642 TSTA3 dimer reduces GDP-KDGal to GDP-Fuc IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6787757 https://reactome.org/PathwayBrowser/#/R-XTR-6787757 PXLP-K333-GADL1 decarboxylates acidic AAs IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6788611 https://reactome.org/PathwayBrowser/#/R-XTR-6788611 HYKK phosphorylates 5HLYS IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6788999 https://reactome.org/PathwayBrowser/#/R-XTR-6788999 HV1-mediated H+ transfer IEA Xenopus tropicalis 15378 R-ALL-1470067 H+ [phagocytic vesicle lumen] R-XTR-6788999 https://reactome.org/PathwayBrowser/#/R-XTR-6788999 HV1-mediated H+ transfer IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6789092 https://reactome.org/PathwayBrowser/#/R-XTR-6789092 NOX2 generates superoxide anion from oxygen IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6793590 https://reactome.org/PathwayBrowser/#/R-XTR-6793590 LIPT2 transfers octanoyl group to GCSH IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6798317 https://reactome.org/PathwayBrowser/#/R-XTR-6798317 GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6798335 https://reactome.org/PathwayBrowser/#/R-XTR-6798335 BPGM dimer isomerises 1,3BPG to 2,3BPG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6799722 https://reactome.org/PathwayBrowser/#/R-XTR-6799722 TP53I3 oxidoreductase generates unstable semiquinones IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6801342 https://reactome.org/PathwayBrowser/#/R-XTR-6801342 MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-6806647 https://reactome.org/PathwayBrowser/#/R-XTR-6806647 VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6806831 https://reactome.org/PathwayBrowser/#/R-XTR-6806831 CYB5Rs reduce MetHb to HbA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6806967 https://reactome.org/PathwayBrowser/#/R-XTR-6806967 CARKD dehydrates S-NAD(P)HX to NADPH IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6807053 https://reactome.org/PathwayBrowser/#/R-XTR-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6807055 https://reactome.org/PathwayBrowser/#/R-XTR-6807055 DHCR7 reduces 7-dehydroCHOL to CHOL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6807064 https://reactome.org/PathwayBrowser/#/R-XTR-6807064 DHCR24 reduces ZYMOL to ZYMSTNL IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6807826 https://reactome.org/PathwayBrowser/#/R-XTR-6807826 LDHAL6B reduces PYR to LACT IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6808464 https://reactome.org/PathwayBrowser/#/R-XTR-6808464 ALDH3B2 oxidises HXAL to PALM IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-6808487 https://reactome.org/PathwayBrowser/#/R-XTR-6808487 ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6808496 https://reactome.org/PathwayBrowser/#/R-XTR-6808496 ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-6809264 https://reactome.org/PathwayBrowser/#/R-XTR-6809264 EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-6809287 https://reactome.org/PathwayBrowser/#/R-XTR-6809287 NUDT12 hydrolyses NADH to NMNH IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-6810474 https://reactome.org/PathwayBrowser/#/R-XTR-6810474 NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6810594 https://reactome.org/PathwayBrowser/#/R-XTR-6810594 HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6813749 https://reactome.org/PathwayBrowser/#/R-XTR-6813749 ALDH1A1 oxidises GA to DGA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6814153 https://reactome.org/PathwayBrowser/#/R-XTR-6814153 ADO oxidises 2AET to HTAU IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-6814165 https://reactome.org/PathwayBrowser/#/R-XTR-6814165 PXLP-K333-GADL1 decarboxylates CSA to HTAU IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70286 https://reactome.org/PathwayBrowser/#/R-XTR-70286 UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70355 https://reactome.org/PathwayBrowser/#/R-XTR-70355 GALK1 phosphorylates Gal to Gal1P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70377 https://reactome.org/PathwayBrowser/#/R-XTR-70377 G6PD multimers dehydrogenate G6P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70420 https://reactome.org/PathwayBrowser/#/R-XTR-70420 HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70449 https://reactome.org/PathwayBrowser/#/R-XTR-70449 GADPH tetramer dehydrogenates GA3P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70482 https://reactome.org/PathwayBrowser/#/R-XTR-70482 GAPDH tetramers reduce 1,3BPG to GA3P IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70501 https://reactome.org/PathwayBrowser/#/R-XTR-70501 PC carboxylates PYR to OA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70510 https://reactome.org/PathwayBrowser/#/R-XTR-70510 LDH tetramer oxidises LACT to PYR IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70589 https://reactome.org/PathwayBrowser/#/R-XTR-70589 alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70599 https://reactome.org/PathwayBrowser/#/R-XTR-70599 aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70600 https://reactome.org/PathwayBrowser/#/R-XTR-70600 glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-70606 https://reactome.org/PathwayBrowser/#/R-XTR-70606 glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70664 https://reactome.org/PathwayBrowser/#/R-XTR-70664 PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70670 https://reactome.org/PathwayBrowser/#/R-XTR-70670 PRODH oxidises L-Pro to 1PYR-5COOH IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70679 https://reactome.org/PathwayBrowser/#/R-XTR-70679 ALDH4A1 oxidises L-GluSS to Glu IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70745 https://reactome.org/PathwayBrowser/#/R-XTR-70745 isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70773 https://reactome.org/PathwayBrowser/#/R-XTR-70773 beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70800 https://reactome.org/PathwayBrowser/#/R-XTR-70800 alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70837 https://reactome.org/PathwayBrowser/#/R-XTR-70837 alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70859 https://reactome.org/PathwayBrowser/#/R-XTR-70859 isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70885 https://reactome.org/PathwayBrowser/#/R-XTR-70885 beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70893 https://reactome.org/PathwayBrowser/#/R-XTR-70893 methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70938 https://reactome.org/PathwayBrowser/#/R-XTR-70938 lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70940 https://reactome.org/PathwayBrowser/#/R-XTR-70940 saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70941 https://reactome.org/PathwayBrowser/#/R-XTR-70941 alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70975 https://reactome.org/PathwayBrowser/#/R-XTR-70975 CS acetylates OA to citrate IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-70979 https://reactome.org/PathwayBrowser/#/R-XTR-70979 MDH2 dimer dehydrogenates MAL IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-71046 https://reactome.org/PathwayBrowser/#/R-XTR-71046 glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71130 https://reactome.org/PathwayBrowser/#/R-XTR-71130 q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71181 https://reactome.org/PathwayBrowser/#/R-XTR-71181 FAH cleaves 4FAA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71200 https://reactome.org/PathwayBrowser/#/R-XTR-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71217 https://reactome.org/PathwayBrowser/#/R-XTR-71217 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71260 https://reactome.org/PathwayBrowser/#/R-XTR-71260 ALDH9A1 tetramer dehydrogenates TEABL to form TEABT IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71286 https://reactome.org/PathwayBrowser/#/R-XTR-71286 guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71296 https://reactome.org/PathwayBrowser/#/R-XTR-71296 PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-71401 https://reactome.org/PathwayBrowser/#/R-XTR-71401 OGDH dimer decarboxylates 2-OG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71588 https://reactome.org/PathwayBrowser/#/R-XTR-71588 glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71670 https://reactome.org/PathwayBrowser/#/R-XTR-71670 PKM dephosphorylates PEP to PYR IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71682 https://reactome.org/PathwayBrowser/#/R-XTR-71682 glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71691 https://reactome.org/PathwayBrowser/#/R-XTR-71691 acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71707 https://reactome.org/PathwayBrowser/#/R-XTR-71707 ethanol + NAD+ => acetaldehyde + NADH + H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-71723 https://reactome.org/PathwayBrowser/#/R-XTR-71723 acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71802 https://reactome.org/PathwayBrowser/#/R-XTR-71802 PFKFKB dimer phosphorylates Fru(6)P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-71849 https://reactome.org/PathwayBrowser/#/R-XTR-71849 LDH tetramer reduces PYR to LACT IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73564 https://reactome.org/PathwayBrowser/#/R-XTR-73564 UMPS dimer decarboxylates OMP to UMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73571 https://reactome.org/PathwayBrowser/#/R-XTR-73571 CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73573 https://reactome.org/PathwayBrowser/#/R-XTR-73573 CAD hexamer transforms CAP to N-carb-L-Asp IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73577 https://reactome.org/PathwayBrowser/#/R-XTR-73577 CAD hexamer transforms L-Gln to CAP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73580 https://reactome.org/PathwayBrowser/#/R-XTR-73580 PRPS dimers pyrophosphorylate R5P using ATP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73585 https://reactome.org/PathwayBrowser/#/R-XTR-73585 uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73596 https://reactome.org/PathwayBrowser/#/R-XTR-73596 dCMP + H2O => dUMP + NH4+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73616 https://reactome.org/PathwayBrowser/#/R-XTR-73616 thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ IEA Xenopus tropicalis 15378 R-ALL-9668967 H+ [nucleoplasm] R-XTR-73666 https://reactome.org/PathwayBrowser/#/R-XTR-73666 dUTP + H2O => dUMP + pyrophosphate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73792 https://reactome.org/PathwayBrowser/#/R-XTR-73792 XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73794 https://reactome.org/PathwayBrowser/#/R-XTR-73794 IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73805 https://reactome.org/PathwayBrowser/#/R-XTR-73805 CAIR + Aspartate + ATP => SAICAR + ADP + Pi IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73806 https://reactome.org/PathwayBrowser/#/R-XTR-73806 AIR + CO2 => CAIR IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73810 https://reactome.org/PathwayBrowser/#/R-XTR-73810 FGAM + ATP => AIR + ADP + Pi IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73812 https://reactome.org/PathwayBrowser/#/R-XTR-73812 FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73813 https://reactome.org/PathwayBrowser/#/R-XTR-73813 GAR + 10-Formyl-THF => FGAR + THF IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-73814 https://reactome.org/PathwayBrowser/#/R-XTR-73814 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-73912 https://reactome.org/PathwayBrowser/#/R-XTR-73912 acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-73920 https://reactome.org/PathwayBrowser/#/R-XTR-73920 D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-74255 https://reactome.org/PathwayBrowser/#/R-XTR-74255 Guanine + H2O => Xanthine + NH4+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-74723 https://reactome.org/PathwayBrowser/#/R-XTR-74723 Endosome acidification IEA Xenopus tropicalis 15378 R-ALL-74722 H+ [endosome lumen] R-XTR-74723 https://reactome.org/PathwayBrowser/#/R-XTR-74723 Endosome acidification IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-74872 https://reactome.org/PathwayBrowser/#/R-XTR-74872 RDH10,11 oxidise 11cROL to 11cRAL IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-749448 https://reactome.org/PathwayBrowser/#/R-XTR-749448 Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-749452 https://reactome.org/PathwayBrowser/#/R-XTR-749452 The Ligand:GPCR:Gq complex dissociates IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-75851 https://reactome.org/PathwayBrowser/#/R-XTR-75851 Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-75872 https://reactome.org/PathwayBrowser/#/R-XTR-75872 Conversion of malonyl-CoA and acetyl-CoA to palmitate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-75883 https://reactome.org/PathwayBrowser/#/R-XTR-75883 DHRS7B reduces GO3P to HXDG3P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-75889 https://reactome.org/PathwayBrowser/#/R-XTR-75889 DHAP is converted to G3P by GPD1/GPD1L IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76354 https://reactome.org/PathwayBrowser/#/R-XTR-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76416 https://reactome.org/PathwayBrowser/#/R-XTR-76416 Benzene is hydroxylated to phenol IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76453 https://reactome.org/PathwayBrowser/#/R-XTR-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76456 https://reactome.org/PathwayBrowser/#/R-XTR-76456 O-atom dealkylation of dextromethorphan IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76466 https://reactome.org/PathwayBrowser/#/R-XTR-76466 CYP4A11 12-hydroxylates DDCX IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-76475 https://reactome.org/PathwayBrowser/#/R-XTR-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77254 https://reactome.org/PathwayBrowser/#/R-XTR-77254 (S)-3-Hydroxydodecanoyl-CoA+NAD<=>3-Oxododecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77283 https://reactome.org/PathwayBrowser/#/R-XTR-77283 (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77303 https://reactome.org/PathwayBrowser/#/R-XTR-77303 (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77312 https://reactome.org/PathwayBrowser/#/R-XTR-77312 (S)-Hydroxybutanoyl-CoA+NAD<=>Acetoacetyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77323 https://reactome.org/PathwayBrowser/#/R-XTR-77323 (S)-Hydroxyhexanoyl-CoA+NAD<=>3-Oxohexanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77331 https://reactome.org/PathwayBrowser/#/R-XTR-77331 (S)-Hydroxyoctanoyl-CoA+NAD<=>3-Oxooctanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-77342 https://reactome.org/PathwayBrowser/#/R-XTR-77342 (S)-Hydroxydecanoyl-CoA+NAD<=>3-Oxodecanoyl-CoA+NADH+H IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-804969 https://reactome.org/PathwayBrowser/#/R-XTR-804969 HSD17B1 hydrogenates E1 to EST17b IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8850846 https://reactome.org/PathwayBrowser/#/R-XTR-8850846 NTPDase1 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8850854 https://reactome.org/PathwayBrowser/#/R-XTR-8850854 NTPDase1 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851089 https://reactome.org/PathwayBrowser/#/R-XTR-8851089 NTPDase2 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851110 https://reactome.org/PathwayBrowser/#/R-XTR-8851110 NTPDase3 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851129 https://reactome.org/PathwayBrowser/#/R-XTR-8851129 NTPDase3 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-8851225 https://reactome.org/PathwayBrowser/#/R-XTR-8851225 NTPDase4 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-8851234 https://reactome.org/PathwayBrowser/#/R-XTR-8851234 NTPDase4 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851396 https://reactome.org/PathwayBrowser/#/R-XTR-8851396 NTPDase6 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-ALL-5228597 H+ [endocytic vesicle lumen] R-XTR-8851494 https://reactome.org/PathwayBrowser/#/R-XTR-8851494 NTPDase7 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851538 https://reactome.org/PathwayBrowser/#/R-XTR-8851538 NTPDase8 hydrolyzes nucleoside triphosphates IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8851550 https://reactome.org/PathwayBrowser/#/R-XTR-8851550 NTPDase8 hydrolyzes nucleoside diphosphates IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-8856223 https://reactome.org/PathwayBrowser/#/R-XTR-8856223 B4GALNT1 dimer transfers GalNAc to gangliosides IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8862137 https://reactome.org/PathwayBrowser/#/R-XTR-8862137 HSD17B2 oxidises estradiol (E2) to estrone (E1) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-8862152 https://reactome.org/PathwayBrowser/#/R-XTR-8862152 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8863494 https://reactome.org/PathwayBrowser/#/R-XTR-8863494 ASICs bind STOML3, (STOM) IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-8863761 https://reactome.org/PathwayBrowser/#/R-XTR-8863761 UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose IEA Xenopus tropicalis 15378 R-ALL-9668967 H+ [nucleoplasm] R-XTR-8866601 https://reactome.org/PathwayBrowser/#/R-XTR-8866601 SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8870346 https://reactome.org/PathwayBrowser/#/R-XTR-8870346 BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8875623 https://reactome.org/PathwayBrowser/#/R-XTR-8875623 SLC25A18,22 import L-Glu, H+ IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-8875623 https://reactome.org/PathwayBrowser/#/R-XTR-8875623 SLC25A18,22 import L-Glu, H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8876889 https://reactome.org/PathwayBrowser/#/R-XTR-8876889 Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-888548 https://reactome.org/PathwayBrowser/#/R-XTR-888548 ALDH5A1 dehydrogenates SUCCSA to SUCCA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-888572 https://reactome.org/PathwayBrowser/#/R-XTR-888572 PXLP-K405-GAD1 decarboxylates L-Glu to form GABA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-888577 https://reactome.org/PathwayBrowser/#/R-XTR-888577 Synthesis of GABA by GAD2 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8936442 https://reactome.org/PathwayBrowser/#/R-XTR-8936442 MARC1,MARC2 reduce N-hydroxylated compounds IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8938076 https://reactome.org/PathwayBrowser/#/R-XTR-8938076 CD38 hydrolyses NAD+ to NAM and ADP-ribose IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8940070 https://reactome.org/PathwayBrowser/#/R-XTR-8940070 NT5E:Zn2+ hydrolyses NAD+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8942575 https://reactome.org/PathwayBrowser/#/R-XTR-8942575 N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-8952873 https://reactome.org/PathwayBrowser/#/R-XTR-8952873 MECR dimer reduces tdec2-CoA to DEC-CoA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-8954468 https://reactome.org/PathwayBrowser/#/R-XTR-8954468 NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-8955030 https://reactome.org/PathwayBrowser/#/R-XTR-8955030 NADK2 dimer phosphorylates NAD+ to NADP+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8955760 https://reactome.org/PathwayBrowser/#/R-XTR-8955760 PGM2L1:Mg2+ phosphorylates G6P to G1,6BP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8955844 https://reactome.org/PathwayBrowser/#/R-XTR-8955844 RBKS phosphorylates ribose to R5P IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-8956458 https://reactome.org/PathwayBrowser/#/R-XTR-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-8959719 https://reactome.org/PathwayBrowser/#/R-XTR-8959719 SHPK phosphorylates Sedo to Sedo7P IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9011595 https://reactome.org/PathwayBrowser/#/R-XTR-9011595 GSTZ1 dimer dehalogenates DCA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9012016 https://reactome.org/PathwayBrowser/#/R-XTR-9012016 FAHD1 dimer hydrolyses OA to PYR IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-9013198 https://reactome.org/PathwayBrowser/#/R-XTR-9013198 TST transfers sulfur from S2O3(2-) to HCN to form HSCN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9024766 https://reactome.org/PathwayBrowser/#/R-XTR-9024766 HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9027043 https://reactome.org/PathwayBrowser/#/R-XTR-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9027302 https://reactome.org/PathwayBrowser/#/R-XTR-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9027321 https://reactome.org/PathwayBrowser/#/R-XTR-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Xenopus tropicalis 15378 R-ALL-74722 H+ [endosome lumen] R-XTR-917811 https://reactome.org/PathwayBrowser/#/R-XTR-917811 STEAP3,STEAP4 reduce Fe3+ to Fe2+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 15378 R-ALL-74722 H+ [endosome lumen] R-XTR-917841 https://reactome.org/PathwayBrowser/#/R-XTR-917841 Acidification of Tf:TfR1 containing endosome IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-917891 https://reactome.org/PathwayBrowser/#/R-XTR-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-917933 https://reactome.org/PathwayBrowser/#/R-XTR-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-917979 https://reactome.org/PathwayBrowser/#/R-XTR-917979 ABCG2 tetramer transports heme from cytosol to extracellular region IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-937311 https://reactome.org/PathwayBrowser/#/R-XTR-937311 ATP12A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-9619024 https://reactome.org/PathwayBrowser/#/R-XTR-9619024 CES1 trimer hydrolyses ACEI pro-drugs to ACEIs IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-9645220 https://reactome.org/PathwayBrowser/#/R-XTR-9645220 SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-9650165 https://reactome.org/PathwayBrowser/#/R-XTR-9650165 ASIC trimers bind H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9695949 https://reactome.org/PathwayBrowser/#/R-XTR-9695949 SPHK2 phosphorylates sphingoid IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9705713 https://reactome.org/PathwayBrowser/#/R-XTR-9705713 SRD5A2 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9705714 https://reactome.org/PathwayBrowser/#/R-XTR-9705714 SRD5A3 dehydrogenates TEST to DHTEST IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-9727198 https://reactome.org/PathwayBrowser/#/R-XTR-9727198 ATP4A:ATP4B exchanges K+ for H+ IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9727347 https://reactome.org/PathwayBrowser/#/R-XTR-9727347 XDH dehydrogenates hypoxanthine to form xanthine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9727349 https://reactome.org/PathwayBrowser/#/R-XTR-9727349 XDH dehydrogenates xanthine to form urate IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9731228 https://reactome.org/PathwayBrowser/#/R-XTR-9731228 NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9731590 https://reactome.org/PathwayBrowser/#/R-XTR-9731590 NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9731613 https://reactome.org/PathwayBrowser/#/R-XTR-9731613 NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9731632 https://reactome.org/PathwayBrowser/#/R-XTR-9731632 NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9731661 https://reactome.org/PathwayBrowser/#/R-XTR-9731661 ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9748945 https://reactome.org/PathwayBrowser/#/R-XTR-9748945 IMPDH tetramers dehydrogenate 6TIMP to 6TXMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9748957 https://reactome.org/PathwayBrowser/#/R-XTR-9748957 GMPS dimer transforms 6TXMP to 6TGMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9748979 https://reactome.org/PathwayBrowser/#/R-XTR-9748979 TPMT transfers methyl group to 6TIMP, forming 6MeTIMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9748983 https://reactome.org/PathwayBrowser/#/R-XTR-9748983 TPMT transfers methyl group to 6MP, forming 6MeMP IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9748991 https://reactome.org/PathwayBrowser/#/R-XTR-9748991 XDH oxidises 6MP to 6TU IEA Xenopus tropicalis 15378 R-ALL-351626 H+ [extracellular region] R-XTR-9749609 https://reactome.org/PathwayBrowser/#/R-XTR-9749609 BCHE hydrolyzes ASA- IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-9749792 https://reactome.org/PathwayBrowser/#/R-XTR-9749792 CES1,CES2 hydrolyze ASA- to ST IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9753285 https://reactome.org/PathwayBrowser/#/R-XTR-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9755937 https://reactome.org/PathwayBrowser/#/R-XTR-9755937 DHCR24 reduces LAN to 24,25-dhLAN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9756138 https://reactome.org/PathwayBrowser/#/R-XTR-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9756162 https://reactome.org/PathwayBrowser/#/R-XTR-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9756169 https://reactome.org/PathwayBrowser/#/R-XTR-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9756177 https://reactome.org/PathwayBrowser/#/R-XTR-9756177 PON1,3 hydrolyse ATVL to ATV IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9756180 https://reactome.org/PathwayBrowser/#/R-XTR-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9757706 https://reactome.org/PathwayBrowser/#/R-XTR-9757706 HSD11B1 hydrogenates PREDN to PREDL in hepatic cell IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9758674 https://reactome.org/PathwayBrowser/#/R-XTR-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9758682 https://reactome.org/PathwayBrowser/#/R-XTR-9758682 AKR1C1 hydrogenates PREDN,PREDL IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9759259 https://reactome.org/PathwayBrowser/#/R-XTR-9759259 HSD11B2 dehydrogenates PREDL to PREDN IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9759549 https://reactome.org/PathwayBrowser/#/R-XTR-9759549 Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-977301 https://reactome.org/PathwayBrowser/#/R-XTR-977301 Histidine is decarboxylated to histamine IEA Xenopus tropicalis 15378 R-ALL-193465 H+ [peroxisomal matrix] R-XTR-977317 https://reactome.org/PathwayBrowser/#/R-XTR-977317 malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-977348 https://reactome.org/PathwayBrowser/#/R-XTR-977348 PHGDH tetramer dehydrogenates 3PG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9773976 https://reactome.org/PathwayBrowser/#/R-XTR-9773976 AKR1E2 reduces 1,5-aF to 1,5-aG IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9837337 https://reactome.org/PathwayBrowser/#/R-XTR-9837337 DCAKD phosphorylates DP-CoA IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9843721 https://reactome.org/PathwayBrowser/#/R-XTR-9843721 ABCC1,ABCG2 transport C18-S1P to extracellular region IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9844587 https://reactome.org/PathwayBrowser/#/R-XTR-9844587 GAL3ST1 transfers sulfate to GalCer,LacCer IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9845516 https://reactome.org/PathwayBrowser/#/R-XTR-9845516 B3GALT4 transfers Gal to gangliosides IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9845538 https://reactome.org/PathwayBrowser/#/R-XTR-9845538 ST3GAL2,3 transfer Neu5Ac to gangliosides IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9845587 https://reactome.org/PathwayBrowser/#/R-XTR-9845587 ST8SIA5 transfers Neu5Ac to gangliosides IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9846305 https://reactome.org/PathwayBrowser/#/R-XTR-9846305 ST6GALNAC5,6 transfer Neu5Ac to GM1b IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9846332 https://reactome.org/PathwayBrowser/#/R-XTR-9846332 FUT1,2 transfer fucose to gangliosides IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9846501 https://reactome.org/PathwayBrowser/#/R-XTR-9846501 B3GNT5 transfers GlcNAc to LacCer IEA Xenopus tropicalis 15378 R-ALL-425969 H+ [Golgi lumen] R-XTR-9851347 https://reactome.org/PathwayBrowser/#/R-XTR-9851347 B4GALT5/6 transfer Gal to GlcCer IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9853499 https://reactome.org/PathwayBrowser/#/R-XTR-9853499 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9854415 https://reactome.org/PathwayBrowser/#/R-XTR-9854415 ACAT1 tetramer acetylates IDH2 dimer IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9856871 https://reactome.org/PathwayBrowser/#/R-XTR-9856871 MDH1 reduces OA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9858321 https://reactome.org/PathwayBrowser/#/R-XTR-9858321 DHTKD1 dimer decarboxylates 2-OA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9858589 https://reactome.org/PathwayBrowser/#/R-XTR-9858589 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9858590 https://reactome.org/PathwayBrowser/#/R-XTR-9858590 DLST transfers glutaryl to CoA IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9859148 https://reactome.org/PathwayBrowser/#/R-XTR-9859148 BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9859172 https://reactome.org/PathwayBrowser/#/R-XTR-9859172 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9861616 https://reactome.org/PathwayBrowser/#/R-XTR-9861616 DLD dimer dehydrogenates dihydrolipoyl IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9861734 https://reactome.org/PathwayBrowser/#/R-XTR-9861734 PDH E1 decarboxylates PYR, transferring acetyl to DLAT IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9864415 https://reactome.org/PathwayBrowser/#/R-XTR-9864415 AAC1 imports a proton IEA Xenopus tropicalis 15378 R-ALL-163953 H+ [mitochondrial intermembrane space] R-XTR-9864415 https://reactome.org/PathwayBrowser/#/R-XTR-9864415 AAC1 imports a proton IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9909159 https://reactome.org/PathwayBrowser/#/R-XTR-9909159 HK1 phosphorylates Mannose to Man6P IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9915971 https://reactome.org/PathwayBrowser/#/R-XTR-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9915997 https://reactome.org/PathwayBrowser/#/R-XTR-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Xenopus tropicalis 15378 R-ALL-113529 H+ [mitochondrial matrix] R-XTR-9929439 https://reactome.org/PathwayBrowser/#/R-XTR-9929439 ALDH4A1 oxidizes 1PYR-3OH-5COOH IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-9935449 https://reactome.org/PathwayBrowser/#/R-XTR-9935449 FUT10 O-fucosylates EMI domain-containing proteins IEA Xenopus tropicalis 15378 R-ALL-156540 H+ [endoplasmic reticulum lumen] R-XTR-9935469 https://reactome.org/PathwayBrowser/#/R-XTR-9935469 FUT11 O-fucosylates EMI domain-containing proteins IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9937295 https://reactome.org/PathwayBrowser/#/R-XTR-9937295 SRD5A3 reduces polyprenal to dolichal IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9937298 https://reactome.org/PathwayBrowser/#/R-XTR-9937298 DHRSX oxidizes polyprenol to polyprenal IEA Xenopus tropicalis 15378 R-ALL-70106 H+ [cytosol] R-XTR-9937340 https://reactome.org/PathwayBrowser/#/R-XTR-9937340 DHRSX reduces dolichal to dolichol IEA Xenopus tropicalis 15379 R-ALL-29368 O2 [cytosol] R-BTA-1222376 https://reactome.org/PathwayBrowser/#/R-BTA-1222376 NOX2 generates superoxide from oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1234164 https://reactome.org/PathwayBrowser/#/R-BTA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-1234165 https://reactome.org/PathwayBrowser/#/R-BTA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1234173 https://reactome.org/PathwayBrowser/#/R-BTA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1234177 https://reactome.org/PathwayBrowser/#/R-BTA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-1234181 https://reactome.org/PathwayBrowser/#/R-BTA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Bos taurus 15379 R-ALL-1236709 O2 [phagolysosome] R-BTA-1236967 https://reactome.org/PathwayBrowser/#/R-BTA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1237119 https://reactome.org/PathwayBrowser/#/R-BTA-1237119 Acireductone is oxidized to MOB IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1237325 https://reactome.org/PathwayBrowser/#/R-BTA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1247668 https://reactome.org/PathwayBrowser/#/R-BTA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-139970 https://reactome.org/PathwayBrowser/#/R-BTA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-140355 https://reactome.org/PathwayBrowser/#/R-BTA-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-141186 https://reactome.org/PathwayBrowser/#/R-BTA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-141200 https://reactome.org/PathwayBrowser/#/R-BTA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-141202 https://reactome.org/PathwayBrowser/#/R-BTA-141202 MAOB:FAD oxidatively deaminates TYR IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-141341 https://reactome.org/PathwayBrowser/#/R-BTA-141341 SMOX-3 oxidises SPN to SPM IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-141348 https://reactome.org/PathwayBrowser/#/R-BTA-141348 PAO:FAD oxidises NASPM to PTCN IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-141351 https://reactome.org/PathwayBrowser/#/R-BTA-141351 PAOX:FAD oxidises NASPN to SPM IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-143468 https://reactome.org/PathwayBrowser/#/R-BTA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1497810 https://reactome.org/PathwayBrowser/#/R-BTA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1562626 https://reactome.org/PathwayBrowser/#/R-BTA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-156526 https://reactome.org/PathwayBrowser/#/R-BTA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159752 https://reactome.org/PathwayBrowser/#/R-BTA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159761 https://reactome.org/PathwayBrowser/#/R-BTA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159795 https://reactome.org/PathwayBrowser/#/R-BTA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159803 https://reactome.org/PathwayBrowser/#/R-BTA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159819 https://reactome.org/PathwayBrowser/#/R-BTA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-159826 https://reactome.org/PathwayBrowser/#/R-BTA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-1614544 https://reactome.org/PathwayBrowser/#/R-BTA-1614544 Sulfite is oxidized to sulfate IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-1614605 https://reactome.org/PathwayBrowser/#/R-BTA-1614605 Persulfide sulfur is dioxygenated IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1614645 https://reactome.org/PathwayBrowser/#/R-BTA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-163214 https://reactome.org/PathwayBrowser/#/R-BTA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-163820 https://reactome.org/PathwayBrowser/#/R-BTA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-1650808 https://reactome.org/PathwayBrowser/#/R-BTA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-1655453 https://reactome.org/PathwayBrowser/#/R-BTA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-189398 https://reactome.org/PathwayBrowser/#/R-BTA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Bos taurus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-BTA-189421 https://reactome.org/PathwayBrowser/#/R-BTA-189421 CPO transforms COPRO3 to PPGEN9 IEA Bos taurus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-BTA-189423 https://reactome.org/PathwayBrowser/#/R-BTA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-191299 https://reactome.org/PathwayBrowser/#/R-BTA-191299 Squalene is oxidized to its epoxide IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-191972 https://reactome.org/PathwayBrowser/#/R-BTA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-191999 https://reactome.org/PathwayBrowser/#/R-BTA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-192051 https://reactome.org/PathwayBrowser/#/R-BTA-192051 CYP7A1 7-hydroxylates CHOL IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-192054 https://reactome.org/PathwayBrowser/#/R-BTA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-192061 https://reactome.org/PathwayBrowser/#/R-BTA-192061 CYP46A1 24-hydroxylates CHOL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-192065 https://reactome.org/PathwayBrowser/#/R-BTA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-192123 https://reactome.org/PathwayBrowser/#/R-BTA-192123 CYP27A1 27-hydroxylates CHOL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-192178 https://reactome.org/PathwayBrowser/#/R-BTA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-192335 https://reactome.org/PathwayBrowser/#/R-BTA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193054 https://reactome.org/PathwayBrowser/#/R-BTA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193060 https://reactome.org/PathwayBrowser/#/R-BTA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193065 https://reactome.org/PathwayBrowser/#/R-BTA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193068 https://reactome.org/PathwayBrowser/#/R-BTA-193068 CYP17A1 17-hydroxylates PREG IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193070 https://reactome.org/PathwayBrowser/#/R-BTA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193072 https://reactome.org/PathwayBrowser/#/R-BTA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193099 https://reactome.org/PathwayBrowser/#/R-BTA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193101 https://reactome.org/PathwayBrowser/#/R-BTA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193143 https://reactome.org/PathwayBrowser/#/R-BTA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-193369 https://reactome.org/PathwayBrowser/#/R-BTA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193393 https://reactome.org/PathwayBrowser/#/R-BTA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193460 https://reactome.org/PathwayBrowser/#/R-BTA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193713 https://reactome.org/PathwayBrowser/#/R-BTA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193719 https://reactome.org/PathwayBrowser/#/R-BTA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193737 https://reactome.org/PathwayBrowser/#/R-BTA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193780 https://reactome.org/PathwayBrowser/#/R-BTA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193787 https://reactome.org/PathwayBrowser/#/R-BTA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193792 https://reactome.org/PathwayBrowser/#/R-BTA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193964 https://reactome.org/PathwayBrowser/#/R-BTA-193964 CYP21A2 21-hydroxylates PROG IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193965 https://reactome.org/PathwayBrowser/#/R-BTA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-193981 https://reactome.org/PathwayBrowser/#/R-BTA-193981 CYP21A2 oxidises 17HPROG IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193995 https://reactome.org/PathwayBrowser/#/R-BTA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-193997 https://reactome.org/PathwayBrowser/#/R-BTA-193997 CYP11B1 oxidises 11DCORT IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-194017 https://reactome.org/PathwayBrowser/#/R-BTA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-194641 https://reactome.org/PathwayBrowser/#/R-BTA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-194669 https://reactome.org/PathwayBrowser/#/R-BTA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-194678 https://reactome.org/PathwayBrowser/#/R-BTA-194678 CYP51A1 demethylates LNSOL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-195664 https://reactome.org/PathwayBrowser/#/R-BTA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-1980233 https://reactome.org/PathwayBrowser/#/R-BTA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-1981104 https://reactome.org/PathwayBrowser/#/R-BTA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-198563 https://reactome.org/PathwayBrowser/#/R-BTA-198563 IDO1 dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-2002466 https://reactome.org/PathwayBrowser/#/R-BTA-2002466 Formation of allysine by LOX IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-202127 https://reactome.org/PathwayBrowser/#/R-BTA-202127 eNOS synthesizes NO IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2046084 https://reactome.org/PathwayBrowser/#/R-BTA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2046089 https://reactome.org/PathwayBrowser/#/R-BTA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2046092 https://reactome.org/PathwayBrowser/#/R-BTA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2046096 https://reactome.org/PathwayBrowser/#/R-BTA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2046097 https://reactome.org/PathwayBrowser/#/R-BTA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-204662 https://reactome.org/PathwayBrowser/#/R-BTA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-2066787 https://reactome.org/PathwayBrowser/#/R-BTA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-209765 https://reactome.org/PathwayBrowser/#/R-BTA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-209823 https://reactome.org/PathwayBrowser/#/R-BTA-209823 Tyrosine is hydroxylated to dopa IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-209828 https://reactome.org/PathwayBrowser/#/R-BTA-209828 Tryptophan is hydroxylated IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-209845 https://reactome.org/PathwayBrowser/#/R-BTA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-209868 https://reactome.org/PathwayBrowser/#/R-BTA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Bos taurus 15379 R-ALL-351593 O2 [secretory granule lumen] R-BTA-209891 https://reactome.org/PathwayBrowser/#/R-BTA-209891 Dopamine is oxidised to noradrenaline IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-211873 https://reactome.org/PathwayBrowser/#/R-BTA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211874 https://reactome.org/PathwayBrowser/#/R-BTA-211874 CYP2S1 4-hydroxylates atRA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211881 https://reactome.org/PathwayBrowser/#/R-BTA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211882 https://reactome.org/PathwayBrowser/#/R-BTA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211904 https://reactome.org/PathwayBrowser/#/R-BTA-211904 CYP4F12 18-hydroxylates ARA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211910 https://reactome.org/PathwayBrowser/#/R-BTA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211919 https://reactome.org/PathwayBrowser/#/R-BTA-211919 CYP4F8 19-hydroxylates PGH2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-211923 https://reactome.org/PathwayBrowser/#/R-BTA-211923 CYP26C1 4-hydroxylates 9cRA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211924 https://reactome.org/PathwayBrowser/#/R-BTA-211924 CYP4B1 12-hydroxylates ARA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211929 https://reactome.org/PathwayBrowser/#/R-BTA-211929 CYP2C19 5-hydroxylates omeprazole IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211948 https://reactome.org/PathwayBrowser/#/R-BTA-211948 CYP3A4 can N-demethylate loperamide IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-211950 https://reactome.org/PathwayBrowser/#/R-BTA-211950 CYP24A1 24-hydroxylates CTL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-211951 https://reactome.org/PathwayBrowser/#/R-BTA-211951 CYP1B1 4-hydroxylates EST17b IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211959 https://reactome.org/PathwayBrowser/#/R-BTA-211959 CYP3A43 6b-hydroxylates TEST IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211960 https://reactome.org/PathwayBrowser/#/R-BTA-211960 CYP2U1 19-hydroxylates ARA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211962 https://reactome.org/PathwayBrowser/#/R-BTA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211966 https://reactome.org/PathwayBrowser/#/R-BTA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211968 https://reactome.org/PathwayBrowser/#/R-BTA-211968 CYP2W1 oxidises INDOL IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211983 https://reactome.org/PathwayBrowser/#/R-BTA-211983 CYP2J2 oxidises ARA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211988 https://reactome.org/PathwayBrowser/#/R-BTA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-211991 https://reactome.org/PathwayBrowser/#/R-BTA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-212004 https://reactome.org/PathwayBrowser/#/R-BTA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-212005 https://reactome.org/PathwayBrowser/#/R-BTA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-212007 https://reactome.org/PathwayBrowser/#/R-BTA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-213175 https://reactome.org/PathwayBrowser/#/R-BTA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-2160492 https://reactome.org/PathwayBrowser/#/R-BTA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161745 https://reactome.org/PathwayBrowser/#/R-BTA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161775 https://reactome.org/PathwayBrowser/#/R-BTA-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161792 https://reactome.org/PathwayBrowser/#/R-BTA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161794 https://reactome.org/PathwayBrowser/#/R-BTA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2161795 https://reactome.org/PathwayBrowser/#/R-BTA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2161814 https://reactome.org/PathwayBrowser/#/R-BTA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161890 https://reactome.org/PathwayBrowser/#/R-BTA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161899 https://reactome.org/PathwayBrowser/#/R-BTA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161907 https://reactome.org/PathwayBrowser/#/R-BTA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161917 https://reactome.org/PathwayBrowser/#/R-BTA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2161940 https://reactome.org/PathwayBrowser/#/R-BTA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161950 https://reactome.org/PathwayBrowser/#/R-BTA-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161951 https://reactome.org/PathwayBrowser/#/R-BTA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2161964 https://reactome.org/PathwayBrowser/#/R-BTA-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-2162002 https://reactome.org/PathwayBrowser/#/R-BTA-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-2162187 https://reactome.org/PathwayBrowser/#/R-BTA-2162187 COQ6 hydroxylates DHB IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-2162194 https://reactome.org/PathwayBrowser/#/R-BTA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-217255 https://reactome.org/PathwayBrowser/#/R-BTA-217255 FMO1:FAD N-oxidises TAM IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-217258 https://reactome.org/PathwayBrowser/#/R-BTA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-2172678 https://reactome.org/PathwayBrowser/#/R-BTA-2172678 PHF8 demethylates histone H4K20me1 IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-2230938 https://reactome.org/PathwayBrowser/#/R-BTA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Bos taurus 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-BTA-2230938 https://reactome.org/PathwayBrowser/#/R-BTA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-2309787 https://reactome.org/PathwayBrowser/#/R-BTA-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-2395340 https://reactome.org/PathwayBrowser/#/R-BTA-2395340 Formation of hydroxyallysine by LOX IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-265296 https://reactome.org/PathwayBrowser/#/R-BTA-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-3204311 https://reactome.org/PathwayBrowser/#/R-BTA-3204311 AOX1 oxidises PXL to PDXate IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-3299680 https://reactome.org/PathwayBrowser/#/R-BTA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-3299682 https://reactome.org/PathwayBrowser/#/R-BTA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-3299691 https://reactome.org/PathwayBrowser/#/R-BTA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Bos taurus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-BTA-3341294 https://reactome.org/PathwayBrowser/#/R-BTA-3341294 Superoxide reduces cytochrome c IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-374909 https://reactome.org/PathwayBrowser/#/R-BTA-374909 Catabolism of Noradrenaline IEA Bos taurus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-BTA-3777112 https://reactome.org/PathwayBrowser/#/R-BTA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-379382 https://reactome.org/PathwayBrowser/#/R-BTA-379382 MAOA:FAD deaminates DA to DOPAC IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-379395 https://reactome.org/PathwayBrowser/#/R-BTA-379395 MAOA:FAD deaminates 3MT to HVA IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389639 https://reactome.org/PathwayBrowser/#/R-BTA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389821 https://reactome.org/PathwayBrowser/#/R-BTA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389842 https://reactome.org/PathwayBrowser/#/R-BTA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389862 https://reactome.org/PathwayBrowser/#/R-BTA-389862 Conversion of glyoxylate to oxalate IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389889 https://reactome.org/PathwayBrowser/#/R-BTA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-389891 https://reactome.org/PathwayBrowser/#/R-BTA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-390256 https://reactome.org/PathwayBrowser/#/R-BTA-390256 ACOX1 oxidizes C26:0 CoA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-418436 https://reactome.org/PathwayBrowser/#/R-BTA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-428259 https://reactome.org/PathwayBrowser/#/R-BTA-428259 DEGS1 dehydrogenates dihydroceramide IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-428260 https://reactome.org/PathwayBrowser/#/R-BTA-428260 DEGS2 oxygenates dihydroceramide IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4722133 https://reactome.org/PathwayBrowser/#/R-BTA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4724279 https://reactome.org/PathwayBrowser/#/R-BTA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4724284 https://reactome.org/PathwayBrowser/#/R-BTA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4754176 https://reactome.org/PathwayBrowser/#/R-BTA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4754181 https://reactome.org/PathwayBrowser/#/R-BTA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-4754187 https://reactome.org/PathwayBrowser/#/R-BTA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-5164399 https://reactome.org/PathwayBrowser/#/R-BTA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5218841 https://reactome.org/PathwayBrowser/#/R-BTA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5340214 https://reactome.org/PathwayBrowser/#/R-BTA-5340214 CYGB binds O2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5340226 https://reactome.org/PathwayBrowser/#/R-BTA-5340226 CYGB dioxygenates NO IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5362525 https://reactome.org/PathwayBrowser/#/R-BTA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5423117 https://reactome.org/PathwayBrowser/#/R-BTA-5423117 PHF8 demethylates MeK21-histone H4 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5423647 https://reactome.org/PathwayBrowser/#/R-BTA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5423664 https://reactome.org/PathwayBrowser/#/R-BTA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5423672 https://reactome.org/PathwayBrowser/#/R-BTA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5423678 https://reactome.org/PathwayBrowser/#/R-BTA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5602295 https://reactome.org/PathwayBrowser/#/R-BTA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5625797 https://reactome.org/PathwayBrowser/#/R-BTA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5625848 https://reactome.org/PathwayBrowser/#/R-BTA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5625870 https://reactome.org/PathwayBrowser/#/R-BTA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661114 https://reactome.org/PathwayBrowser/#/R-BTA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661115 https://reactome.org/PathwayBrowser/#/R-BTA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661116 https://reactome.org/PathwayBrowser/#/R-BTA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661120 https://reactome.org/PathwayBrowser/#/R-BTA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661121 https://reactome.org/PathwayBrowser/#/R-BTA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661122 https://reactome.org/PathwayBrowser/#/R-BTA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661124 https://reactome.org/PathwayBrowser/#/R-BTA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-5661125 https://reactome.org/PathwayBrowser/#/R-BTA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Bos taurus 15379 R-ALL-5668566 O2 [melanosome lumen] R-BTA-5662692 https://reactome.org/PathwayBrowser/#/R-BTA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Bos taurus 15379 R-ALL-1236709 O2 [phagolysosome] R-BTA-5668629 https://reactome.org/PathwayBrowser/#/R-BTA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5668718 https://reactome.org/PathwayBrowser/#/R-BTA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5668731 https://reactome.org/PathwayBrowser/#/R-BTA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5678327 https://reactome.org/PathwayBrowser/#/R-BTA-5678327 MIOX oxidises Ins to GlcA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5690565 https://reactome.org/PathwayBrowser/#/R-BTA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-5691107 https://reactome.org/PathwayBrowser/#/R-BTA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5693681 https://reactome.org/PathwayBrowser/#/R-BTA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5693761 https://reactome.org/PathwayBrowser/#/R-BTA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-5696119 https://reactome.org/PathwayBrowser/#/R-BTA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5696131 https://reactome.org/PathwayBrowser/#/R-BTA-5696131 AOC1 deaminates Hist IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5696146 https://reactome.org/PathwayBrowser/#/R-BTA-5696146 AOC2 deaminates TYR IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-5696183 https://reactome.org/PathwayBrowser/#/R-BTA-5696183 AOC3 deaminates BZAM IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-6783880 https://reactome.org/PathwayBrowser/#/R-BTA-6783880 PIPOX oxidises PPCA to P6C IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-6786239 https://reactome.org/PathwayBrowser/#/R-BTA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-6787811 https://reactome.org/PathwayBrowser/#/R-BTA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Bos taurus 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-BTA-6789092 https://reactome.org/PathwayBrowser/#/R-BTA-6789092 NOX2 generates superoxide anion from oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-6807053 https://reactome.org/PathwayBrowser/#/R-BTA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-6807214 https://reactome.org/PathwayBrowser/#/R-BTA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-6807557 https://reactome.org/PathwayBrowser/#/R-BTA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-6810076 https://reactome.org/PathwayBrowser/#/R-BTA-6810076 DDO oxidizes D-Asp to OA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-6814153 https://reactome.org/PathwayBrowser/#/R-BTA-6814153 ADO oxidises 2AET to HTAU IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71118 https://reactome.org/PathwayBrowser/#/R-BTA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71163 https://reactome.org/PathwayBrowser/#/R-BTA-71163 HPD dioxygenates HPP IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71164 https://reactome.org/PathwayBrowser/#/R-BTA-71164 HGD dioxygenates homogentisate IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71188 https://reactome.org/PathwayBrowser/#/R-BTA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71200 https://reactome.org/PathwayBrowser/#/R-BTA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71218 https://reactome.org/PathwayBrowser/#/R-BTA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-71241 https://reactome.org/PathwayBrowser/#/R-BTA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-71261 https://reactome.org/PathwayBrowser/#/R-BTA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-74247 https://reactome.org/PathwayBrowser/#/R-BTA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-74258 https://reactome.org/PathwayBrowser/#/R-BTA-74258 XDH oxidizes xanthine to form urate IEA Bos taurus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-BTA-76031 https://reactome.org/PathwayBrowser/#/R-BTA-76031 2 H2O2 => O2 + 2 H2O IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76354 https://reactome.org/PathwayBrowser/#/R-BTA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76373 https://reactome.org/PathwayBrowser/#/R-BTA-76373 N-hydroxylation of 4-aminobiphenyl IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76386 https://reactome.org/PathwayBrowser/#/R-BTA-76386 CYP1A2 S-demethylates 6MMP IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76397 https://reactome.org/PathwayBrowser/#/R-BTA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76416 https://reactome.org/PathwayBrowser/#/R-BTA-76416 Benzene is hydroxylated to phenol IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76426 https://reactome.org/PathwayBrowser/#/R-BTA-76426 N-atom dealkylation of caffeine IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76453 https://reactome.org/PathwayBrowser/#/R-BTA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76456 https://reactome.org/PathwayBrowser/#/R-BTA-76456 O-atom dealkylation of dextromethorphan IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76466 https://reactome.org/PathwayBrowser/#/R-BTA-76466 CYP4A11 12-hydroxylates DDCX IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76472 https://reactome.org/PathwayBrowser/#/R-BTA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-76475 https://reactome.org/PathwayBrowser/#/R-BTA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8847579 https://reactome.org/PathwayBrowser/#/R-BTA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Bos taurus 15379 R-ALL-5668566 O2 [melanosome lumen] R-BTA-8878581 https://reactome.org/PathwayBrowser/#/R-BTA-8878581 TYRP1 oxidises DHICA to IQCA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-888614 https://reactome.org/PathwayBrowser/#/R-BTA-888614 IDO2 dioxygenates L-Trp to NFK IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-8953398 https://reactome.org/PathwayBrowser/#/R-BTA-8953398 PIR oxygenates quercetin IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-8956458 https://reactome.org/PathwayBrowser/#/R-BTA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8981606 https://reactome.org/PathwayBrowser/#/R-BTA-8981606 Myoglobin binds oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8981610 https://reactome.org/PathwayBrowser/#/R-BTA-8981610 Neuroglobin binds oxygen IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8981621 https://reactome.org/PathwayBrowser/#/R-BTA-8981621 Neuroglobin:oxygen dissociates IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8981622 https://reactome.org/PathwayBrowser/#/R-BTA-8981622 Myoglobin:oxygen dissociates IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-8982617 https://reactome.org/PathwayBrowser/#/R-BTA-8982617 CYGB:O2 dissociates IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018858 https://reactome.org/PathwayBrowser/#/R-BTA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018859 https://reactome.org/PathwayBrowser/#/R-BTA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018863 https://reactome.org/PathwayBrowser/#/R-BTA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018880 https://reactome.org/PathwayBrowser/#/R-BTA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018894 https://reactome.org/PathwayBrowser/#/R-BTA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9018907 https://reactome.org/PathwayBrowser/#/R-BTA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020251 https://reactome.org/PathwayBrowser/#/R-BTA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020259 https://reactome.org/PathwayBrowser/#/R-BTA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020261 https://reactome.org/PathwayBrowser/#/R-BTA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020264 https://reactome.org/PathwayBrowser/#/R-BTA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020274 https://reactome.org/PathwayBrowser/#/R-BTA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020275 https://reactome.org/PathwayBrowser/#/R-BTA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020282 https://reactome.org/PathwayBrowser/#/R-BTA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9020610 https://reactome.org/PathwayBrowser/#/R-BTA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9024872 https://reactome.org/PathwayBrowser/#/R-BTA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9024997 https://reactome.org/PathwayBrowser/#/R-BTA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9025152 https://reactome.org/PathwayBrowser/#/R-BTA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9025957 https://reactome.org/PathwayBrowser/#/R-BTA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9025996 https://reactome.org/PathwayBrowser/#/R-BTA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9026003 https://reactome.org/PathwayBrowser/#/R-BTA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9026005 https://reactome.org/PathwayBrowser/#/R-BTA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9026006 https://reactome.org/PathwayBrowser/#/R-BTA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9026405 https://reactome.org/PathwayBrowser/#/R-BTA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9026408 https://reactome.org/PathwayBrowser/#/R-BTA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027043 https://reactome.org/PathwayBrowser/#/R-BTA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027302 https://reactome.org/PathwayBrowser/#/R-BTA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027321 https://reactome.org/PathwayBrowser/#/R-BTA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027532 https://reactome.org/PathwayBrowser/#/R-BTA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027607 https://reactome.org/PathwayBrowser/#/R-BTA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027624 https://reactome.org/PathwayBrowser/#/R-BTA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027627 https://reactome.org/PathwayBrowser/#/R-BTA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027628 https://reactome.org/PathwayBrowser/#/R-BTA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9027633 https://reactome.org/PathwayBrowser/#/R-BTA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9028255 https://reactome.org/PathwayBrowser/#/R-BTA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9037761 https://reactome.org/PathwayBrowser/#/R-BTA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-917891 https://reactome.org/PathwayBrowser/#/R-BTA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-917933 https://reactome.org/PathwayBrowser/#/R-BTA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9629578 https://reactome.org/PathwayBrowser/#/R-BTA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9629591 https://reactome.org/PathwayBrowser/#/R-BTA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9629869 https://reactome.org/PathwayBrowser/#/R-BTA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9629888 https://reactome.org/PathwayBrowser/#/R-BTA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9629946 https://reactome.org/PathwayBrowser/#/R-BTA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-9630022 https://reactome.org/PathwayBrowser/#/R-BTA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-9630769 https://reactome.org/PathwayBrowser/#/R-BTA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-9630967 https://reactome.org/PathwayBrowser/#/R-BTA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-BTA-9630993 https://reactome.org/PathwayBrowser/#/R-BTA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9631356 https://reactome.org/PathwayBrowser/#/R-BTA-9631356 ASPH:Fe2+ hydroxylates an aspartate residue of F9 TAS Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-965019 https://reactome.org/PathwayBrowser/#/R-BTA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-965079 https://reactome.org/PathwayBrowser/#/R-BTA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Bos taurus 15379 R-ALL-352327 O2 [extracellular region] R-BTA-9709360 https://reactome.org/PathwayBrowser/#/R-BTA-9709360 H2O2 reduces MetHb IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9749986 https://reactome.org/PathwayBrowser/#/R-BTA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9750016 https://reactome.org/PathwayBrowser/#/R-BTA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9753285 https://reactome.org/PathwayBrowser/#/R-BTA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9756138 https://reactome.org/PathwayBrowser/#/R-BTA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9756162 https://reactome.org/PathwayBrowser/#/R-BTA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9756169 https://reactome.org/PathwayBrowser/#/R-BTA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9756180 https://reactome.org/PathwayBrowser/#/R-BTA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-975635 https://reactome.org/PathwayBrowser/#/R-BTA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9758674 https://reactome.org/PathwayBrowser/#/R-BTA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9817575 https://reactome.org/PathwayBrowser/#/R-BTA-9817575 ERO1B oxidizes P4HB IEA Bos taurus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-BTA-9856718 https://reactome.org/PathwayBrowser/#/R-BTA-9856718 HPDL dioxygenates HPPA IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9915971 https://reactome.org/PathwayBrowser/#/R-BTA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9915992 https://reactome.org/PathwayBrowser/#/R-BTA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Bos taurus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-BTA-9915993 https://reactome.org/PathwayBrowser/#/R-BTA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9915997 https://reactome.org/PathwayBrowser/#/R-BTA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Bos taurus 15379 R-ALL-29368 O2 [cytosol] R-BTA-9916401 https://reactome.org/PathwayBrowser/#/R-BTA-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Bos taurus 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-1234165 https://reactome.org/PathwayBrowser/#/R-CEL-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1234173 https://reactome.org/PathwayBrowser/#/R-CEL-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1234177 https://reactome.org/PathwayBrowser/#/R-CEL-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-1234181 https://reactome.org/PathwayBrowser/#/R-CEL-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1237119 https://reactome.org/PathwayBrowser/#/R-CEL-1237119 Acireductone is oxidized to MOB IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-139970 https://reactome.org/PathwayBrowser/#/R-CEL-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-141348 https://reactome.org/PathwayBrowser/#/R-CEL-141348 PAO:FAD oxidises NASPM to PTCN IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-141351 https://reactome.org/PathwayBrowser/#/R-CEL-141351 PAOX:FAD oxidises NASPN to SPM IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-143468 https://reactome.org/PathwayBrowser/#/R-CEL-143468 MEOS oxidizes ethanol to acetaldehyde IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1497810 https://reactome.org/PathwayBrowser/#/R-CEL-1497810 Uncoupled eNOS favours the formation of superoxide IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1562626 https://reactome.org/PathwayBrowser/#/R-CEL-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-156526 https://reactome.org/PathwayBrowser/#/R-CEL-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-1614544 https://reactome.org/PathwayBrowser/#/R-CEL-1614544 Sulfite is oxidized to sulfate IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-1614605 https://reactome.org/PathwayBrowser/#/R-CEL-1614605 Persulfide sulfur is dioxygenated IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1614645 https://reactome.org/PathwayBrowser/#/R-CEL-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-1650808 https://reactome.org/PathwayBrowser/#/R-CEL-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-1655453 https://reactome.org/PathwayBrowser/#/R-CEL-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-191983 https://reactome.org/PathwayBrowser/#/R-CEL-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-192335 https://reactome.org/PathwayBrowser/#/R-CEL-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-193060 https://reactome.org/PathwayBrowser/#/R-CEL-193060 CYP19A1 hydroxylates ANDST to E1 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-193143 https://reactome.org/PathwayBrowser/#/R-CEL-193143 CYP19A1 hydroxylates TEST to EST17b IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-193369 https://reactome.org/PathwayBrowser/#/R-CEL-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-1981104 https://reactome.org/PathwayBrowser/#/R-CEL-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-202127 https://reactome.org/PathwayBrowser/#/R-CEL-202127 eNOS synthesizes NO IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2046084 https://reactome.org/PathwayBrowser/#/R-CEL-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2046089 https://reactome.org/PathwayBrowser/#/R-CEL-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2046092 https://reactome.org/PathwayBrowser/#/R-CEL-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2046096 https://reactome.org/PathwayBrowser/#/R-CEL-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2046097 https://reactome.org/PathwayBrowser/#/R-CEL-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-204662 https://reactome.org/PathwayBrowser/#/R-CEL-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-2066787 https://reactome.org/PathwayBrowser/#/R-CEL-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-209823 https://reactome.org/PathwayBrowser/#/R-CEL-209823 Tyrosine is hydroxylated to dopa IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-209828 https://reactome.org/PathwayBrowser/#/R-CEL-209828 Tryptophan is hydroxylated IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-209845 https://reactome.org/PathwayBrowser/#/R-CEL-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211874 https://reactome.org/PathwayBrowser/#/R-CEL-211874 CYP2S1 4-hydroxylates atRA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211881 https://reactome.org/PathwayBrowser/#/R-CEL-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211910 https://reactome.org/PathwayBrowser/#/R-CEL-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211929 https://reactome.org/PathwayBrowser/#/R-CEL-211929 CYP2C19 5-hydroxylates omeprazole IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211966 https://reactome.org/PathwayBrowser/#/R-CEL-211966 CYP2D6 4-hydroxylates debrisoquine IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211968 https://reactome.org/PathwayBrowser/#/R-CEL-211968 CYP2W1 oxidises INDOL IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211983 https://reactome.org/PathwayBrowser/#/R-CEL-211983 CYP2J2 oxidises ARA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211988 https://reactome.org/PathwayBrowser/#/R-CEL-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-211991 https://reactome.org/PathwayBrowser/#/R-CEL-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-212004 https://reactome.org/PathwayBrowser/#/R-CEL-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-212005 https://reactome.org/PathwayBrowser/#/R-CEL-212005 CYP2F1 dehydrogenates 3-methylindole IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-2161814 https://reactome.org/PathwayBrowser/#/R-CEL-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-2161890 https://reactome.org/PathwayBrowser/#/R-CEL-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-2161899 https://reactome.org/PathwayBrowser/#/R-CEL-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-2162187 https://reactome.org/PathwayBrowser/#/R-CEL-2162187 COQ6 hydroxylates DHB IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-217255 https://reactome.org/PathwayBrowser/#/R-CEL-217255 FMO1:FAD N-oxidises TAM IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-217258 https://reactome.org/PathwayBrowser/#/R-CEL-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-2172678 https://reactome.org/PathwayBrowser/#/R-CEL-2172678 PHF8 demethylates histone H4K20me1 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-3204311 https://reactome.org/PathwayBrowser/#/R-CEL-3204311 AOX1 oxidises PXL to PDXate IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-3299680 https://reactome.org/PathwayBrowser/#/R-CEL-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-3299691 https://reactome.org/PathwayBrowser/#/R-CEL-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Caenorhabditis elegans 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CEL-3341294 https://reactome.org/PathwayBrowser/#/R-CEL-3341294 Superoxide reduces cytochrome c IEA Caenorhabditis elegans 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CEL-3777112 https://reactome.org/PathwayBrowser/#/R-CEL-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389639 https://reactome.org/PathwayBrowser/#/R-CEL-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389821 https://reactome.org/PathwayBrowser/#/R-CEL-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389842 https://reactome.org/PathwayBrowser/#/R-CEL-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389862 https://reactome.org/PathwayBrowser/#/R-CEL-389862 Conversion of glyoxylate to oxalate IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389889 https://reactome.org/PathwayBrowser/#/R-CEL-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-389891 https://reactome.org/PathwayBrowser/#/R-CEL-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-390256 https://reactome.org/PathwayBrowser/#/R-CEL-390256 ACOX1 oxidizes C26:0 CoA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-428259 https://reactome.org/PathwayBrowser/#/R-CEL-428259 DEGS1 dehydrogenates dihydroceramide IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-428260 https://reactome.org/PathwayBrowser/#/R-CEL-428260 DEGS2 oxygenates dihydroceramide IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4722133 https://reactome.org/PathwayBrowser/#/R-CEL-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4724279 https://reactome.org/PathwayBrowser/#/R-CEL-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4724284 https://reactome.org/PathwayBrowser/#/R-CEL-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4754176 https://reactome.org/PathwayBrowser/#/R-CEL-4754176 JMJD6 demethylates MeR3-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4754181 https://reactome.org/PathwayBrowser/#/R-CEL-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-4754187 https://reactome.org/PathwayBrowser/#/R-CEL-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-5164399 https://reactome.org/PathwayBrowser/#/R-CEL-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5340214 https://reactome.org/PathwayBrowser/#/R-CEL-5340214 CYGB binds O2 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5340226 https://reactome.org/PathwayBrowser/#/R-CEL-5340226 CYGB dioxygenates NO IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5423117 https://reactome.org/PathwayBrowser/#/R-CEL-5423117 PHF8 demethylates MeK21-histone H4 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5423647 https://reactome.org/PathwayBrowser/#/R-CEL-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661114 https://reactome.org/PathwayBrowser/#/R-CEL-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661115 https://reactome.org/PathwayBrowser/#/R-CEL-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661116 https://reactome.org/PathwayBrowser/#/R-CEL-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661120 https://reactome.org/PathwayBrowser/#/R-CEL-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661121 https://reactome.org/PathwayBrowser/#/R-CEL-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661122 https://reactome.org/PathwayBrowser/#/R-CEL-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661124 https://reactome.org/PathwayBrowser/#/R-CEL-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-5661125 https://reactome.org/PathwayBrowser/#/R-CEL-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Caenorhabditis elegans 15379 R-ALL-5668566 O2 [melanosome lumen] R-CEL-5662692 https://reactome.org/PathwayBrowser/#/R-CEL-5662692 Dopa is oxidized to dopaquinone by TYR IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5678327 https://reactome.org/PathwayBrowser/#/R-CEL-5678327 MIOX oxidises Ins to GlcA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5690565 https://reactome.org/PathwayBrowser/#/R-CEL-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-5691107 https://reactome.org/PathwayBrowser/#/R-CEL-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Caenorhabditis elegans 15379 R-ALL-352327 O2 [extracellular region] R-CEL-5693681 https://reactome.org/PathwayBrowser/#/R-CEL-5693681 DUOX1,2 reduce O2 to H2O2 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5693761 https://reactome.org/PathwayBrowser/#/R-CEL-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-5696119 https://reactome.org/PathwayBrowser/#/R-CEL-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-6783880 https://reactome.org/PathwayBrowser/#/R-CEL-6783880 PIPOX oxidises PPCA to P6C IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-6786239 https://reactome.org/PathwayBrowser/#/R-CEL-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-6787811 https://reactome.org/PathwayBrowser/#/R-CEL-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-6810076 https://reactome.org/PathwayBrowser/#/R-CEL-6810076 DDO oxidizes D-Asp to OA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-6814153 https://reactome.org/PathwayBrowser/#/R-CEL-6814153 ADO oxidises 2AET to HTAU IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71118 https://reactome.org/PathwayBrowser/#/R-CEL-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71163 https://reactome.org/PathwayBrowser/#/R-CEL-71163 HPD dioxygenates HPP IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71164 https://reactome.org/PathwayBrowser/#/R-CEL-71164 HGD dioxygenates homogentisate IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71188 https://reactome.org/PathwayBrowser/#/R-CEL-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71200 https://reactome.org/PathwayBrowser/#/R-CEL-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71218 https://reactome.org/PathwayBrowser/#/R-CEL-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Caenorhabditis elegans 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CEL-71241 https://reactome.org/PathwayBrowser/#/R-CEL-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-71261 https://reactome.org/PathwayBrowser/#/R-CEL-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-74247 https://reactome.org/PathwayBrowser/#/R-CEL-74247 XDH oxidizes hypoxanthine to form xanthine IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-74258 https://reactome.org/PathwayBrowser/#/R-CEL-74258 XDH oxidizes xanthine to form urate IEA Caenorhabditis elegans 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CEL-76031 https://reactome.org/PathwayBrowser/#/R-CEL-76031 2 H2O2 => O2 + 2 H2O IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76354 https://reactome.org/PathwayBrowser/#/R-CEL-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76397 https://reactome.org/PathwayBrowser/#/R-CEL-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76416 https://reactome.org/PathwayBrowser/#/R-CEL-76416 Benzene is hydroxylated to phenol IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76453 https://reactome.org/PathwayBrowser/#/R-CEL-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76456 https://reactome.org/PathwayBrowser/#/R-CEL-76456 O-atom dealkylation of dextromethorphan IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-76475 https://reactome.org/PathwayBrowser/#/R-CEL-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-8847579 https://reactome.org/PathwayBrowser/#/R-CEL-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-8865107 https://reactome.org/PathwayBrowser/#/R-CEL-8865107 MICAL1 produces NADP+, H2O2 IEA Caenorhabditis elegans 15379 R-ALL-5668566 O2 [melanosome lumen] R-CEL-8878581 https://reactome.org/PathwayBrowser/#/R-CEL-8878581 TYRP1 oxidises DHICA to IQCA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-8981610 https://reactome.org/PathwayBrowser/#/R-CEL-8981610 Neuroglobin binds oxygen IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-8981621 https://reactome.org/PathwayBrowser/#/R-CEL-8981621 Neuroglobin:oxygen dissociates IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-8982617 https://reactome.org/PathwayBrowser/#/R-CEL-8982617 CYGB:O2 dissociates IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9027043 https://reactome.org/PathwayBrowser/#/R-CEL-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9027302 https://reactome.org/PathwayBrowser/#/R-CEL-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9027321 https://reactome.org/PathwayBrowser/#/R-CEL-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9629869 https://reactome.org/PathwayBrowser/#/R-CEL-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9629888 https://reactome.org/PathwayBrowser/#/R-CEL-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9629946 https://reactome.org/PathwayBrowser/#/R-CEL-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-9630022 https://reactome.org/PathwayBrowser/#/R-CEL-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-9630769 https://reactome.org/PathwayBrowser/#/R-CEL-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Caenorhabditis elegans 15379 R-ALL-113685 O2 [nucleoplasm] R-CEL-9630993 https://reactome.org/PathwayBrowser/#/R-CEL-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-965019 https://reactome.org/PathwayBrowser/#/R-CEL-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-965079 https://reactome.org/PathwayBrowser/#/R-CEL-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-9749986 https://reactome.org/PathwayBrowser/#/R-CEL-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-9750016 https://reactome.org/PathwayBrowser/#/R-CEL-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9753285 https://reactome.org/PathwayBrowser/#/R-CEL-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-975635 https://reactome.org/PathwayBrowser/#/R-CEL-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Caenorhabditis elegans 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CEL-9817575 https://reactome.org/PathwayBrowser/#/R-CEL-9817575 ERO1B oxidizes P4HB IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9915971 https://reactome.org/PathwayBrowser/#/R-CEL-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CEL-9915997 https://reactome.org/PathwayBrowser/#/R-CEL-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Caenorhabditis elegans 15379 R-ALL-29368 O2 [cytosol] R-CFA-1222376 https://reactome.org/PathwayBrowser/#/R-CFA-1222376 NOX2 generates superoxide from oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1234164 https://reactome.org/PathwayBrowser/#/R-CFA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-1234165 https://reactome.org/PathwayBrowser/#/R-CFA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1234173 https://reactome.org/PathwayBrowser/#/R-CFA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1234177 https://reactome.org/PathwayBrowser/#/R-CFA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-1234181 https://reactome.org/PathwayBrowser/#/R-CFA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Canis familiaris 15379 R-ALL-1236709 O2 [phagolysosome] R-CFA-1236967 https://reactome.org/PathwayBrowser/#/R-CFA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1237119 https://reactome.org/PathwayBrowser/#/R-CFA-1237119 Acireductone is oxidized to MOB IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1237325 https://reactome.org/PathwayBrowser/#/R-CFA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1247668 https://reactome.org/PathwayBrowser/#/R-CFA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-139970 https://reactome.org/PathwayBrowser/#/R-CFA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-140355 https://reactome.org/PathwayBrowser/#/R-CFA-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-141186 https://reactome.org/PathwayBrowser/#/R-CFA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-141200 https://reactome.org/PathwayBrowser/#/R-CFA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-141202 https://reactome.org/PathwayBrowser/#/R-CFA-141202 MAOB:FAD oxidatively deaminates TYR IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-141341 https://reactome.org/PathwayBrowser/#/R-CFA-141341 SMOX-3 oxidises SPN to SPM IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-141348 https://reactome.org/PathwayBrowser/#/R-CFA-141348 PAO:FAD oxidises NASPM to PTCN IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-141351 https://reactome.org/PathwayBrowser/#/R-CFA-141351 PAOX:FAD oxidises NASPN to SPM IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-143468 https://reactome.org/PathwayBrowser/#/R-CFA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1562626 https://reactome.org/PathwayBrowser/#/R-CFA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-156526 https://reactome.org/PathwayBrowser/#/R-CFA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159752 https://reactome.org/PathwayBrowser/#/R-CFA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159761 https://reactome.org/PathwayBrowser/#/R-CFA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159795 https://reactome.org/PathwayBrowser/#/R-CFA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159803 https://reactome.org/PathwayBrowser/#/R-CFA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159819 https://reactome.org/PathwayBrowser/#/R-CFA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-159826 https://reactome.org/PathwayBrowser/#/R-CFA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-1614544 https://reactome.org/PathwayBrowser/#/R-CFA-1614544 Sulfite is oxidized to sulfate IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-1614605 https://reactome.org/PathwayBrowser/#/R-CFA-1614605 Persulfide sulfur is dioxygenated IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1614645 https://reactome.org/PathwayBrowser/#/R-CFA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-163214 https://reactome.org/PathwayBrowser/#/R-CFA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-1650808 https://reactome.org/PathwayBrowser/#/R-CFA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-1655453 https://reactome.org/PathwayBrowser/#/R-CFA-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-189398 https://reactome.org/PathwayBrowser/#/R-CFA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Canis familiaris 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CFA-189421 https://reactome.org/PathwayBrowser/#/R-CFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Canis familiaris 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CFA-189423 https://reactome.org/PathwayBrowser/#/R-CFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-191299 https://reactome.org/PathwayBrowser/#/R-CFA-191299 Squalene is oxidized to its epoxide IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-191972 https://reactome.org/PathwayBrowser/#/R-CFA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-191999 https://reactome.org/PathwayBrowser/#/R-CFA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-192051 https://reactome.org/PathwayBrowser/#/R-CFA-192051 CYP7A1 7-hydroxylates CHOL IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-192054 https://reactome.org/PathwayBrowser/#/R-CFA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-192061 https://reactome.org/PathwayBrowser/#/R-CFA-192061 CYP46A1 24-hydroxylates CHOL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-192065 https://reactome.org/PathwayBrowser/#/R-CFA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-192123 https://reactome.org/PathwayBrowser/#/R-CFA-192123 CYP27A1 27-hydroxylates CHOL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-192157 https://reactome.org/PathwayBrowser/#/R-CFA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-192178 https://reactome.org/PathwayBrowser/#/R-CFA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-192335 https://reactome.org/PathwayBrowser/#/R-CFA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193054 https://reactome.org/PathwayBrowser/#/R-CFA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193060 https://reactome.org/PathwayBrowser/#/R-CFA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193065 https://reactome.org/PathwayBrowser/#/R-CFA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193068 https://reactome.org/PathwayBrowser/#/R-CFA-193068 CYP17A1 17-hydroxylates PREG IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193070 https://reactome.org/PathwayBrowser/#/R-CFA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193072 https://reactome.org/PathwayBrowser/#/R-CFA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193099 https://reactome.org/PathwayBrowser/#/R-CFA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193101 https://reactome.org/PathwayBrowser/#/R-CFA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193143 https://reactome.org/PathwayBrowser/#/R-CFA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-193369 https://reactome.org/PathwayBrowser/#/R-CFA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193393 https://reactome.org/PathwayBrowser/#/R-CFA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193460 https://reactome.org/PathwayBrowser/#/R-CFA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193709 https://reactome.org/PathwayBrowser/#/R-CFA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193713 https://reactome.org/PathwayBrowser/#/R-CFA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193719 https://reactome.org/PathwayBrowser/#/R-CFA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193737 https://reactome.org/PathwayBrowser/#/R-CFA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193780 https://reactome.org/PathwayBrowser/#/R-CFA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193787 https://reactome.org/PathwayBrowser/#/R-CFA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193792 https://reactome.org/PathwayBrowser/#/R-CFA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193845 https://reactome.org/PathwayBrowser/#/R-CFA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193964 https://reactome.org/PathwayBrowser/#/R-CFA-193964 CYP21A2 21-hydroxylates PROG IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193965 https://reactome.org/PathwayBrowser/#/R-CFA-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-193981 https://reactome.org/PathwayBrowser/#/R-CFA-193981 CYP21A2 oxidises 17HPROG IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193995 https://reactome.org/PathwayBrowser/#/R-CFA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-193997 https://reactome.org/PathwayBrowser/#/R-CFA-193997 CYP11B1 oxidises 11DCORT IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-194017 https://reactome.org/PathwayBrowser/#/R-CFA-194017 CYP11B2 oxidises 11DCORST to CORST IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-194641 https://reactome.org/PathwayBrowser/#/R-CFA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-194669 https://reactome.org/PathwayBrowser/#/R-CFA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-194678 https://reactome.org/PathwayBrowser/#/R-CFA-194678 CYP51A1 demethylates LNSOL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-195664 https://reactome.org/PathwayBrowser/#/R-CFA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-1980233 https://reactome.org/PathwayBrowser/#/R-CFA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-1981104 https://reactome.org/PathwayBrowser/#/R-CFA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-198563 https://reactome.org/PathwayBrowser/#/R-CFA-198563 IDO1 dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-2002466 https://reactome.org/PathwayBrowser/#/R-CFA-2002466 Formation of allysine by LOX IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2046084 https://reactome.org/PathwayBrowser/#/R-CFA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2046089 https://reactome.org/PathwayBrowser/#/R-CFA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2046092 https://reactome.org/PathwayBrowser/#/R-CFA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2046096 https://reactome.org/PathwayBrowser/#/R-CFA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2046097 https://reactome.org/PathwayBrowser/#/R-CFA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-204662 https://reactome.org/PathwayBrowser/#/R-CFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-2066787 https://reactome.org/PathwayBrowser/#/R-CFA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-209765 https://reactome.org/PathwayBrowser/#/R-CFA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-209823 https://reactome.org/PathwayBrowser/#/R-CFA-209823 Tyrosine is hydroxylated to dopa IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-209828 https://reactome.org/PathwayBrowser/#/R-CFA-209828 Tryptophan is hydroxylated IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-209845 https://reactome.org/PathwayBrowser/#/R-CFA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-209868 https://reactome.org/PathwayBrowser/#/R-CFA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Canis familiaris 15379 R-ALL-351593 O2 [secretory granule lumen] R-CFA-209891 https://reactome.org/PathwayBrowser/#/R-CFA-209891 Dopamine is oxidised to noradrenaline IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-211873 https://reactome.org/PathwayBrowser/#/R-CFA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211874 https://reactome.org/PathwayBrowser/#/R-CFA-211874 CYP2S1 4-hydroxylates atRA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211881 https://reactome.org/PathwayBrowser/#/R-CFA-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211882 https://reactome.org/PathwayBrowser/#/R-CFA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211904 https://reactome.org/PathwayBrowser/#/R-CFA-211904 CYP4F12 18-hydroxylates ARA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211919 https://reactome.org/PathwayBrowser/#/R-CFA-211919 CYP4F8 19-hydroxylates PGH2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-211923 https://reactome.org/PathwayBrowser/#/R-CFA-211923 CYP26C1 4-hydroxylates 9cRA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211924 https://reactome.org/PathwayBrowser/#/R-CFA-211924 CYP4B1 12-hydroxylates ARA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211948 https://reactome.org/PathwayBrowser/#/R-CFA-211948 CYP3A4 can N-demethylate loperamide IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-211950 https://reactome.org/PathwayBrowser/#/R-CFA-211950 CYP24A1 24-hydroxylates CTL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-211951 https://reactome.org/PathwayBrowser/#/R-CFA-211951 CYP1B1 4-hydroxylates EST17b IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211959 https://reactome.org/PathwayBrowser/#/R-CFA-211959 CYP3A43 6b-hydroxylates TEST IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211960 https://reactome.org/PathwayBrowser/#/R-CFA-211960 CYP2U1 19-hydroxylates ARA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211962 https://reactome.org/PathwayBrowser/#/R-CFA-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211966 https://reactome.org/PathwayBrowser/#/R-CFA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211968 https://reactome.org/PathwayBrowser/#/R-CFA-211968 CYP2W1 oxidises INDOL IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211983 https://reactome.org/PathwayBrowser/#/R-CFA-211983 CYP2J2 oxidises ARA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-211991 https://reactome.org/PathwayBrowser/#/R-CFA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-212005 https://reactome.org/PathwayBrowser/#/R-CFA-212005 CYP2F1 dehydrogenates 3-methylindole IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-212007 https://reactome.org/PathwayBrowser/#/R-CFA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-213175 https://reactome.org/PathwayBrowser/#/R-CFA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-2160492 https://reactome.org/PathwayBrowser/#/R-CFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161745 https://reactome.org/PathwayBrowser/#/R-CFA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161775 https://reactome.org/PathwayBrowser/#/R-CFA-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161792 https://reactome.org/PathwayBrowser/#/R-CFA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161794 https://reactome.org/PathwayBrowser/#/R-CFA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2161795 https://reactome.org/PathwayBrowser/#/R-CFA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2161814 https://reactome.org/PathwayBrowser/#/R-CFA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161890 https://reactome.org/PathwayBrowser/#/R-CFA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161899 https://reactome.org/PathwayBrowser/#/R-CFA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161907 https://reactome.org/PathwayBrowser/#/R-CFA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161917 https://reactome.org/PathwayBrowser/#/R-CFA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2161940 https://reactome.org/PathwayBrowser/#/R-CFA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161950 https://reactome.org/PathwayBrowser/#/R-CFA-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161951 https://reactome.org/PathwayBrowser/#/R-CFA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2161964 https://reactome.org/PathwayBrowser/#/R-CFA-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-2162002 https://reactome.org/PathwayBrowser/#/R-CFA-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-2162187 https://reactome.org/PathwayBrowser/#/R-CFA-2162187 COQ6 hydroxylates DHB IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-2162194 https://reactome.org/PathwayBrowser/#/R-CFA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-217255 https://reactome.org/PathwayBrowser/#/R-CFA-217255 FMO1:FAD N-oxidises TAM IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-217258 https://reactome.org/PathwayBrowser/#/R-CFA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-2172678 https://reactome.org/PathwayBrowser/#/R-CFA-2172678 PHF8 demethylates histone H4K20me1 IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-2230938 https://reactome.org/PathwayBrowser/#/R-CFA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Canis familiaris 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-CFA-2230938 https://reactome.org/PathwayBrowser/#/R-CFA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-2309787 https://reactome.org/PathwayBrowser/#/R-CFA-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-2395340 https://reactome.org/PathwayBrowser/#/R-CFA-2395340 Formation of hydroxyallysine by LOX IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-265296 https://reactome.org/PathwayBrowser/#/R-CFA-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-3299680 https://reactome.org/PathwayBrowser/#/R-CFA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-3299682 https://reactome.org/PathwayBrowser/#/R-CFA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-3299691 https://reactome.org/PathwayBrowser/#/R-CFA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Canis familiaris 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CFA-3341294 https://reactome.org/PathwayBrowser/#/R-CFA-3341294 Superoxide reduces cytochrome c IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-374909 https://reactome.org/PathwayBrowser/#/R-CFA-374909 Catabolism of Noradrenaline IEA Canis familiaris 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-CFA-3777112 https://reactome.org/PathwayBrowser/#/R-CFA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-379382 https://reactome.org/PathwayBrowser/#/R-CFA-379382 MAOA:FAD deaminates DA to DOPAC IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-379395 https://reactome.org/PathwayBrowser/#/R-CFA-379395 MAOA:FAD deaminates 3MT to HVA IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389639 https://reactome.org/PathwayBrowser/#/R-CFA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389821 https://reactome.org/PathwayBrowser/#/R-CFA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389842 https://reactome.org/PathwayBrowser/#/R-CFA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389862 https://reactome.org/PathwayBrowser/#/R-CFA-389862 Conversion of glyoxylate to oxalate IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389889 https://reactome.org/PathwayBrowser/#/R-CFA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-389891 https://reactome.org/PathwayBrowser/#/R-CFA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-390256 https://reactome.org/PathwayBrowser/#/R-CFA-390256 ACOX1 oxidizes C26:0 CoA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-418436 https://reactome.org/PathwayBrowser/#/R-CFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-428259 https://reactome.org/PathwayBrowser/#/R-CFA-428259 DEGS1 dehydrogenates dihydroceramide IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-428260 https://reactome.org/PathwayBrowser/#/R-CFA-428260 DEGS2 oxygenates dihydroceramide IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4722133 https://reactome.org/PathwayBrowser/#/R-CFA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4724279 https://reactome.org/PathwayBrowser/#/R-CFA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4724284 https://reactome.org/PathwayBrowser/#/R-CFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4754176 https://reactome.org/PathwayBrowser/#/R-CFA-4754176 JMJD6 demethylates MeR3-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4754181 https://reactome.org/PathwayBrowser/#/R-CFA-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-4754187 https://reactome.org/PathwayBrowser/#/R-CFA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-5164399 https://reactome.org/PathwayBrowser/#/R-CFA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5218841 https://reactome.org/PathwayBrowser/#/R-CFA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5340214 https://reactome.org/PathwayBrowser/#/R-CFA-5340214 CYGB binds O2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5340226 https://reactome.org/PathwayBrowser/#/R-CFA-5340226 CYGB dioxygenates NO IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5362525 https://reactome.org/PathwayBrowser/#/R-CFA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5423117 https://reactome.org/PathwayBrowser/#/R-CFA-5423117 PHF8 demethylates MeK21-histone H4 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5423647 https://reactome.org/PathwayBrowser/#/R-CFA-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5423664 https://reactome.org/PathwayBrowser/#/R-CFA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5423672 https://reactome.org/PathwayBrowser/#/R-CFA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5602295 https://reactome.org/PathwayBrowser/#/R-CFA-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5625797 https://reactome.org/PathwayBrowser/#/R-CFA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5625848 https://reactome.org/PathwayBrowser/#/R-CFA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5625870 https://reactome.org/PathwayBrowser/#/R-CFA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661114 https://reactome.org/PathwayBrowser/#/R-CFA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661115 https://reactome.org/PathwayBrowser/#/R-CFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661116 https://reactome.org/PathwayBrowser/#/R-CFA-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661120 https://reactome.org/PathwayBrowser/#/R-CFA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661121 https://reactome.org/PathwayBrowser/#/R-CFA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661122 https://reactome.org/PathwayBrowser/#/R-CFA-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661124 https://reactome.org/PathwayBrowser/#/R-CFA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-5661125 https://reactome.org/PathwayBrowser/#/R-CFA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Canis familiaris 15379 R-ALL-5668566 O2 [melanosome lumen] R-CFA-5662692 https://reactome.org/PathwayBrowser/#/R-CFA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Canis familiaris 15379 R-ALL-1236709 O2 [phagolysosome] R-CFA-5668629 https://reactome.org/PathwayBrowser/#/R-CFA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5668718 https://reactome.org/PathwayBrowser/#/R-CFA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5668731 https://reactome.org/PathwayBrowser/#/R-CFA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5678327 https://reactome.org/PathwayBrowser/#/R-CFA-5678327 MIOX oxidises Ins to GlcA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5690565 https://reactome.org/PathwayBrowser/#/R-CFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-5691107 https://reactome.org/PathwayBrowser/#/R-CFA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5693681 https://reactome.org/PathwayBrowser/#/R-CFA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5693761 https://reactome.org/PathwayBrowser/#/R-CFA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-5696119 https://reactome.org/PathwayBrowser/#/R-CFA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5696146 https://reactome.org/PathwayBrowser/#/R-CFA-5696146 AOC2 deaminates TYR IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-5696183 https://reactome.org/PathwayBrowser/#/R-CFA-5696183 AOC3 deaminates BZAM IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-6783880 https://reactome.org/PathwayBrowser/#/R-CFA-6783880 PIPOX oxidises PPCA to P6C IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-6786239 https://reactome.org/PathwayBrowser/#/R-CFA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-6787811 https://reactome.org/PathwayBrowser/#/R-CFA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Canis familiaris 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-CFA-6789092 https://reactome.org/PathwayBrowser/#/R-CFA-6789092 NOX2 generates superoxide anion from oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-6807053 https://reactome.org/PathwayBrowser/#/R-CFA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-6807214 https://reactome.org/PathwayBrowser/#/R-CFA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-6807557 https://reactome.org/PathwayBrowser/#/R-CFA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-6810076 https://reactome.org/PathwayBrowser/#/R-CFA-6810076 DDO oxidizes D-Asp to OA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-6814153 https://reactome.org/PathwayBrowser/#/R-CFA-6814153 ADO oxidises 2AET to HTAU IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71118 https://reactome.org/PathwayBrowser/#/R-CFA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71163 https://reactome.org/PathwayBrowser/#/R-CFA-71163 HPD dioxygenates HPP IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71164 https://reactome.org/PathwayBrowser/#/R-CFA-71164 HGD dioxygenates homogentisate IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71188 https://reactome.org/PathwayBrowser/#/R-CFA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71200 https://reactome.org/PathwayBrowser/#/R-CFA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71218 https://reactome.org/PathwayBrowser/#/R-CFA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-71241 https://reactome.org/PathwayBrowser/#/R-CFA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-71261 https://reactome.org/PathwayBrowser/#/R-CFA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-74247 https://reactome.org/PathwayBrowser/#/R-CFA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-74258 https://reactome.org/PathwayBrowser/#/R-CFA-74258 XDH oxidizes xanthine to form urate IEA Canis familiaris 15379 R-ALL-113535 O2 [peroxisomal matrix] R-CFA-76031 https://reactome.org/PathwayBrowser/#/R-CFA-76031 2 H2O2 => O2 + 2 H2O IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76354 https://reactome.org/PathwayBrowser/#/R-CFA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76397 https://reactome.org/PathwayBrowser/#/R-CFA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76416 https://reactome.org/PathwayBrowser/#/R-CFA-76416 Benzene is hydroxylated to phenol IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76453 https://reactome.org/PathwayBrowser/#/R-CFA-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76456 https://reactome.org/PathwayBrowser/#/R-CFA-76456 O-atom dealkylation of dextromethorphan IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76466 https://reactome.org/PathwayBrowser/#/R-CFA-76466 CYP4A11 12-hydroxylates DDCX IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-76475 https://reactome.org/PathwayBrowser/#/R-CFA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8847579 https://reactome.org/PathwayBrowser/#/R-CFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Canis familiaris 15379 R-ALL-5668566 O2 [melanosome lumen] R-CFA-8878581 https://reactome.org/PathwayBrowser/#/R-CFA-8878581 TYRP1 oxidises DHICA to IQCA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-888614 https://reactome.org/PathwayBrowser/#/R-CFA-888614 IDO2 dioxygenates L-Trp to NFK IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-8953398 https://reactome.org/PathwayBrowser/#/R-CFA-8953398 PIR oxygenates quercetin IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-8956458 https://reactome.org/PathwayBrowser/#/R-CFA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8981606 https://reactome.org/PathwayBrowser/#/R-CFA-8981606 Myoglobin binds oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8981610 https://reactome.org/PathwayBrowser/#/R-CFA-8981610 Neuroglobin binds oxygen IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8981621 https://reactome.org/PathwayBrowser/#/R-CFA-8981621 Neuroglobin:oxygen dissociates IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8981622 https://reactome.org/PathwayBrowser/#/R-CFA-8981622 Myoglobin:oxygen dissociates IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-8982617 https://reactome.org/PathwayBrowser/#/R-CFA-8982617 CYGB:O2 dissociates IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018858 https://reactome.org/PathwayBrowser/#/R-CFA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018859 https://reactome.org/PathwayBrowser/#/R-CFA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018863 https://reactome.org/PathwayBrowser/#/R-CFA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018880 https://reactome.org/PathwayBrowser/#/R-CFA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018894 https://reactome.org/PathwayBrowser/#/R-CFA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9018907 https://reactome.org/PathwayBrowser/#/R-CFA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020251 https://reactome.org/PathwayBrowser/#/R-CFA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020259 https://reactome.org/PathwayBrowser/#/R-CFA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020261 https://reactome.org/PathwayBrowser/#/R-CFA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020264 https://reactome.org/PathwayBrowser/#/R-CFA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020274 https://reactome.org/PathwayBrowser/#/R-CFA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020275 https://reactome.org/PathwayBrowser/#/R-CFA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020282 https://reactome.org/PathwayBrowser/#/R-CFA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9020610 https://reactome.org/PathwayBrowser/#/R-CFA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9024872 https://reactome.org/PathwayBrowser/#/R-CFA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9024997 https://reactome.org/PathwayBrowser/#/R-CFA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9025152 https://reactome.org/PathwayBrowser/#/R-CFA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9025957 https://reactome.org/PathwayBrowser/#/R-CFA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9025996 https://reactome.org/PathwayBrowser/#/R-CFA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9026003 https://reactome.org/PathwayBrowser/#/R-CFA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9026005 https://reactome.org/PathwayBrowser/#/R-CFA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9026006 https://reactome.org/PathwayBrowser/#/R-CFA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9026405 https://reactome.org/PathwayBrowser/#/R-CFA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9026408 https://reactome.org/PathwayBrowser/#/R-CFA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027043 https://reactome.org/PathwayBrowser/#/R-CFA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027302 https://reactome.org/PathwayBrowser/#/R-CFA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027321 https://reactome.org/PathwayBrowser/#/R-CFA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027532 https://reactome.org/PathwayBrowser/#/R-CFA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027607 https://reactome.org/PathwayBrowser/#/R-CFA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027624 https://reactome.org/PathwayBrowser/#/R-CFA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027627 https://reactome.org/PathwayBrowser/#/R-CFA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027628 https://reactome.org/PathwayBrowser/#/R-CFA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9027633 https://reactome.org/PathwayBrowser/#/R-CFA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9028255 https://reactome.org/PathwayBrowser/#/R-CFA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-917891 https://reactome.org/PathwayBrowser/#/R-CFA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-917933 https://reactome.org/PathwayBrowser/#/R-CFA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9629578 https://reactome.org/PathwayBrowser/#/R-CFA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9629591 https://reactome.org/PathwayBrowser/#/R-CFA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9629869 https://reactome.org/PathwayBrowser/#/R-CFA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9629888 https://reactome.org/PathwayBrowser/#/R-CFA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9629946 https://reactome.org/PathwayBrowser/#/R-CFA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-9630022 https://reactome.org/PathwayBrowser/#/R-CFA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-9630769 https://reactome.org/PathwayBrowser/#/R-CFA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-9630967 https://reactome.org/PathwayBrowser/#/R-CFA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Canis familiaris 15379 R-ALL-113685 O2 [nucleoplasm] R-CFA-9630993 https://reactome.org/PathwayBrowser/#/R-CFA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-965019 https://reactome.org/PathwayBrowser/#/R-CFA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-965079 https://reactome.org/PathwayBrowser/#/R-CFA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Canis familiaris 15379 R-ALL-352327 O2 [extracellular region] R-CFA-9709360 https://reactome.org/PathwayBrowser/#/R-CFA-9709360 H2O2 reduces MetHb IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-9749986 https://reactome.org/PathwayBrowser/#/R-CFA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-9750016 https://reactome.org/PathwayBrowser/#/R-CFA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9753285 https://reactome.org/PathwayBrowser/#/R-CFA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9756138 https://reactome.org/PathwayBrowser/#/R-CFA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9756162 https://reactome.org/PathwayBrowser/#/R-CFA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9756169 https://reactome.org/PathwayBrowser/#/R-CFA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9756180 https://reactome.org/PathwayBrowser/#/R-CFA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-975635 https://reactome.org/PathwayBrowser/#/R-CFA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9758674 https://reactome.org/PathwayBrowser/#/R-CFA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-9817575 https://reactome.org/PathwayBrowser/#/R-CFA-9817575 ERO1B oxidizes P4HB IEA Canis familiaris 15379 R-ALL-113533 O2 [mitochondrial matrix] R-CFA-9856718 https://reactome.org/PathwayBrowser/#/R-CFA-9856718 HPDL dioxygenates HPPA IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9915971 https://reactome.org/PathwayBrowser/#/R-CFA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-9915992 https://reactome.org/PathwayBrowser/#/R-CFA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Canis familiaris 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-CFA-9915993 https://reactome.org/PathwayBrowser/#/R-CFA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9915997 https://reactome.org/PathwayBrowser/#/R-CFA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-CFA-9916401 https://reactome.org/PathwayBrowser/#/R-CFA-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Canis familiaris 15379 R-ALL-29368 O2 [cytosol] R-DDI-1237119 https://reactome.org/PathwayBrowser/#/R-DDI-1237119 Acireductone is oxidized to MOB IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-139970 https://reactome.org/PathwayBrowser/#/R-DDI-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-141186 https://reactome.org/PathwayBrowser/#/R-DDI-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-141200 https://reactome.org/PathwayBrowser/#/R-DDI-141200 MAOB:FAD oxidatively deaminates of PEA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-141202 https://reactome.org/PathwayBrowser/#/R-DDI-141202 MAOB:FAD oxidatively deaminates TYR IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-143468 https://reactome.org/PathwayBrowser/#/R-DDI-143468 MEOS oxidizes ethanol to acetaldehyde IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-1497810 https://reactome.org/PathwayBrowser/#/R-DDI-1497810 Uncoupled eNOS favours the formation of superoxide IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-156526 https://reactome.org/PathwayBrowser/#/R-DDI-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Dictyostelium discoideum 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DDI-1614544 https://reactome.org/PathwayBrowser/#/R-DDI-1614544 Sulfite is oxidized to sulfate IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-1614645 https://reactome.org/PathwayBrowser/#/R-DDI-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-1655453 https://reactome.org/PathwayBrowser/#/R-DDI-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Dictyostelium discoideum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DDI-189421 https://reactome.org/PathwayBrowser/#/R-DDI-189421 CPO transforms COPRO3 to PPGEN9 IEA Dictyostelium discoideum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DDI-189423 https://reactome.org/PathwayBrowser/#/R-DDI-189423 PPO oxidises PPGEN9 to PRIN9 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-191299 https://reactome.org/PathwayBrowser/#/R-DDI-191299 Squalene is oxidized to its epoxide IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-191983 https://reactome.org/PathwayBrowser/#/R-DDI-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-192335 https://reactome.org/PathwayBrowser/#/R-DDI-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-193369 https://reactome.org/PathwayBrowser/#/R-DDI-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-193964 https://reactome.org/PathwayBrowser/#/R-DDI-193964 CYP21A2 21-hydroxylates PROG IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-193981 https://reactome.org/PathwayBrowser/#/R-DDI-193981 CYP21A2 oxidises 17HPROG IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-194641 https://reactome.org/PathwayBrowser/#/R-DDI-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-194669 https://reactome.org/PathwayBrowser/#/R-DDI-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-194678 https://reactome.org/PathwayBrowser/#/R-DDI-194678 CYP51A1 demethylates LNSOL IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-202127 https://reactome.org/PathwayBrowser/#/R-DDI-202127 eNOS synthesizes NO IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-204662 https://reactome.org/PathwayBrowser/#/R-DDI-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-2066787 https://reactome.org/PathwayBrowser/#/R-DDI-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-209823 https://reactome.org/PathwayBrowser/#/R-DDI-209823 Tyrosine is hydroxylated to dopa IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-209828 https://reactome.org/PathwayBrowser/#/R-DDI-209828 Tryptophan is hydroxylated IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-209845 https://reactome.org/PathwayBrowser/#/R-DDI-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211874 https://reactome.org/PathwayBrowser/#/R-DDI-211874 CYP2S1 4-hydroxylates atRA IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211881 https://reactome.org/PathwayBrowser/#/R-DDI-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211910 https://reactome.org/PathwayBrowser/#/R-DDI-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211929 https://reactome.org/PathwayBrowser/#/R-DDI-211929 CYP2C19 5-hydroxylates omeprazole IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211960 https://reactome.org/PathwayBrowser/#/R-DDI-211960 CYP2U1 19-hydroxylates ARA IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211966 https://reactome.org/PathwayBrowser/#/R-DDI-211966 CYP2D6 4-hydroxylates debrisoquine IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211968 https://reactome.org/PathwayBrowser/#/R-DDI-211968 CYP2W1 oxidises INDOL IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211983 https://reactome.org/PathwayBrowser/#/R-DDI-211983 CYP2J2 oxidises ARA IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211988 https://reactome.org/PathwayBrowser/#/R-DDI-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-211991 https://reactome.org/PathwayBrowser/#/R-DDI-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-212004 https://reactome.org/PathwayBrowser/#/R-DDI-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-212005 https://reactome.org/PathwayBrowser/#/R-DDI-212005 CYP2F1 dehydrogenates 3-methylindole IEA Dictyostelium discoideum 15379 R-ALL-352327 O2 [extracellular region] R-DDI-2160492 https://reactome.org/PathwayBrowser/#/R-DDI-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161775 https://reactome.org/PathwayBrowser/#/R-DDI-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161794 https://reactome.org/PathwayBrowser/#/R-DDI-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-2161814 https://reactome.org/PathwayBrowser/#/R-DDI-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161890 https://reactome.org/PathwayBrowser/#/R-DDI-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161899 https://reactome.org/PathwayBrowser/#/R-DDI-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161907 https://reactome.org/PathwayBrowser/#/R-DDI-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161917 https://reactome.org/PathwayBrowser/#/R-DDI-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-2161940 https://reactome.org/PathwayBrowser/#/R-DDI-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161950 https://reactome.org/PathwayBrowser/#/R-DDI-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2161964 https://reactome.org/PathwayBrowser/#/R-DDI-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-2162002 https://reactome.org/PathwayBrowser/#/R-DDI-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Dictyostelium discoideum 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DDI-2162187 https://reactome.org/PathwayBrowser/#/R-DDI-2162187 COQ6 hydroxylates DHB IEA Dictyostelium discoideum 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DDI-2162194 https://reactome.org/PathwayBrowser/#/R-DDI-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-217255 https://reactome.org/PathwayBrowser/#/R-DDI-217255 FMO1:FAD N-oxidises TAM IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-217258 https://reactome.org/PathwayBrowser/#/R-DDI-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-2172678 https://reactome.org/PathwayBrowser/#/R-DDI-2172678 PHF8 demethylates histone H4K20me1 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-265296 https://reactome.org/PathwayBrowser/#/R-DDI-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-3204311 https://reactome.org/PathwayBrowser/#/R-DDI-3204311 AOX1 oxidises PXL to PDXate IEA Dictyostelium discoideum 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DDI-3299680 https://reactome.org/PathwayBrowser/#/R-DDI-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Dictyostelium discoideum 15379 R-ALL-352327 O2 [extracellular region] R-DDI-3299682 https://reactome.org/PathwayBrowser/#/R-DDI-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-3299691 https://reactome.org/PathwayBrowser/#/R-DDI-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Dictyostelium discoideum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DDI-3341294 https://reactome.org/PathwayBrowser/#/R-DDI-3341294 Superoxide reduces cytochrome c IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-374909 https://reactome.org/PathwayBrowser/#/R-DDI-374909 Catabolism of Noradrenaline IEA Dictyostelium discoideum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DDI-3777112 https://reactome.org/PathwayBrowser/#/R-DDI-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-379382 https://reactome.org/PathwayBrowser/#/R-DDI-379382 MAOA:FAD deaminates DA to DOPAC IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-379395 https://reactome.org/PathwayBrowser/#/R-DDI-379395 MAOA:FAD deaminates 3MT to HVA IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389639 https://reactome.org/PathwayBrowser/#/R-DDI-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389821 https://reactome.org/PathwayBrowser/#/R-DDI-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389842 https://reactome.org/PathwayBrowser/#/R-DDI-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389862 https://reactome.org/PathwayBrowser/#/R-DDI-389862 Conversion of glyoxylate to oxalate IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389889 https://reactome.org/PathwayBrowser/#/R-DDI-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-389891 https://reactome.org/PathwayBrowser/#/R-DDI-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-390256 https://reactome.org/PathwayBrowser/#/R-DDI-390256 ACOX1 oxidizes C26:0 CoA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-418436 https://reactome.org/PathwayBrowser/#/R-DDI-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-428259 https://reactome.org/PathwayBrowser/#/R-DDI-428259 DEGS1 dehydrogenates dihydroceramide IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-428260 https://reactome.org/PathwayBrowser/#/R-DDI-428260 DEGS2 oxygenates dihydroceramide IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-4754181 https://reactome.org/PathwayBrowser/#/R-DDI-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-4754187 https://reactome.org/PathwayBrowser/#/R-DDI-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-5423647 https://reactome.org/PathwayBrowser/#/R-DDI-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-5661116 https://reactome.org/PathwayBrowser/#/R-DDI-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-5661121 https://reactome.org/PathwayBrowser/#/R-DDI-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Dictyostelium discoideum 15379 R-ALL-5668566 O2 [melanosome lumen] R-DDI-5662692 https://reactome.org/PathwayBrowser/#/R-DDI-5662692 Dopa is oxidized to dopaquinone by TYR IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-5678327 https://reactome.org/PathwayBrowser/#/R-DDI-5678327 MIOX oxidises Ins to GlcA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-5690565 https://reactome.org/PathwayBrowser/#/R-DDI-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15379 R-ALL-352327 O2 [extracellular region] R-DDI-5693681 https://reactome.org/PathwayBrowser/#/R-DDI-5693681 DUOX1,2 reduce O2 to H2O2 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-5693761 https://reactome.org/PathwayBrowser/#/R-DDI-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-5696119 https://reactome.org/PathwayBrowser/#/R-DDI-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-6783880 https://reactome.org/PathwayBrowser/#/R-DDI-6783880 PIPOX oxidises PPCA to P6C IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-6787811 https://reactome.org/PathwayBrowser/#/R-DDI-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-6807557 https://reactome.org/PathwayBrowser/#/R-DDI-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-6810076 https://reactome.org/PathwayBrowser/#/R-DDI-6810076 DDO oxidizes D-Asp to OA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-6814153 https://reactome.org/PathwayBrowser/#/R-DDI-6814153 ADO oxidises 2AET to HTAU IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71118 https://reactome.org/PathwayBrowser/#/R-DDI-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71163 https://reactome.org/PathwayBrowser/#/R-DDI-71163 HPD dioxygenates HPP IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71164 https://reactome.org/PathwayBrowser/#/R-DDI-71164 HGD dioxygenates homogentisate IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71188 https://reactome.org/PathwayBrowser/#/R-DDI-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71200 https://reactome.org/PathwayBrowser/#/R-DDI-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-71218 https://reactome.org/PathwayBrowser/#/R-DDI-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-74247 https://reactome.org/PathwayBrowser/#/R-DDI-74247 XDH oxidizes hypoxanthine to form xanthine IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-74258 https://reactome.org/PathwayBrowser/#/R-DDI-74258 XDH oxidizes xanthine to form urate IEA Dictyostelium discoideum 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DDI-76031 https://reactome.org/PathwayBrowser/#/R-DDI-76031 2 H2O2 => O2 + 2 H2O IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76354 https://reactome.org/PathwayBrowser/#/R-DDI-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76397 https://reactome.org/PathwayBrowser/#/R-DDI-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76416 https://reactome.org/PathwayBrowser/#/R-DDI-76416 Benzene is hydroxylated to phenol IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76453 https://reactome.org/PathwayBrowser/#/R-DDI-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76456 https://reactome.org/PathwayBrowser/#/R-DDI-76456 O-atom dealkylation of dextromethorphan IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-76475 https://reactome.org/PathwayBrowser/#/R-DDI-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-8847579 https://reactome.org/PathwayBrowser/#/R-DDI-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-8865107 https://reactome.org/PathwayBrowser/#/R-DDI-8865107 MICAL1 produces NADP+, H2O2 IEA Dictyostelium discoideum 15379 R-ALL-5668566 O2 [melanosome lumen] R-DDI-8878581 https://reactome.org/PathwayBrowser/#/R-DDI-8878581 TYRP1 oxidises DHICA to IQCA IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-8953398 https://reactome.org/PathwayBrowser/#/R-DDI-8953398 PIR oxygenates quercetin IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9018858 https://reactome.org/PathwayBrowser/#/R-DDI-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9018859 https://reactome.org/PathwayBrowser/#/R-DDI-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9018863 https://reactome.org/PathwayBrowser/#/R-DDI-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9018894 https://reactome.org/PathwayBrowser/#/R-DDI-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9018907 https://reactome.org/PathwayBrowser/#/R-DDI-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020251 https://reactome.org/PathwayBrowser/#/R-DDI-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020259 https://reactome.org/PathwayBrowser/#/R-DDI-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020264 https://reactome.org/PathwayBrowser/#/R-DDI-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020274 https://reactome.org/PathwayBrowser/#/R-DDI-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020275 https://reactome.org/PathwayBrowser/#/R-DDI-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020282 https://reactome.org/PathwayBrowser/#/R-DDI-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9020610 https://reactome.org/PathwayBrowser/#/R-DDI-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9024872 https://reactome.org/PathwayBrowser/#/R-DDI-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9024997 https://reactome.org/PathwayBrowser/#/R-DDI-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9025152 https://reactome.org/PathwayBrowser/#/R-DDI-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9025957 https://reactome.org/PathwayBrowser/#/R-DDI-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9025996 https://reactome.org/PathwayBrowser/#/R-DDI-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9026003 https://reactome.org/PathwayBrowser/#/R-DDI-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9026005 https://reactome.org/PathwayBrowser/#/R-DDI-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9026006 https://reactome.org/PathwayBrowser/#/R-DDI-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9026405 https://reactome.org/PathwayBrowser/#/R-DDI-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027043 https://reactome.org/PathwayBrowser/#/R-DDI-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027302 https://reactome.org/PathwayBrowser/#/R-DDI-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027321 https://reactome.org/PathwayBrowser/#/R-DDI-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027624 https://reactome.org/PathwayBrowser/#/R-DDI-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027628 https://reactome.org/PathwayBrowser/#/R-DDI-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9027633 https://reactome.org/PathwayBrowser/#/R-DDI-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9629578 https://reactome.org/PathwayBrowser/#/R-DDI-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9629591 https://reactome.org/PathwayBrowser/#/R-DDI-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9629869 https://reactome.org/PathwayBrowser/#/R-DDI-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DDI-9630993 https://reactome.org/PathwayBrowser/#/R-DDI-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-965019 https://reactome.org/PathwayBrowser/#/R-DDI-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-965079 https://reactome.org/PathwayBrowser/#/R-DDI-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-9749986 https://reactome.org/PathwayBrowser/#/R-DDI-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-9750016 https://reactome.org/PathwayBrowser/#/R-DDI-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9753285 https://reactome.org/PathwayBrowser/#/R-DDI-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Dictyostelium discoideum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DDI-9817575 https://reactome.org/PathwayBrowser/#/R-DDI-9817575 ERO1B oxidizes P4HB IEA Dictyostelium discoideum 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DDI-9856718 https://reactome.org/PathwayBrowser/#/R-DDI-9856718 HPDL dioxygenates HPPA IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9915971 https://reactome.org/PathwayBrowser/#/R-DDI-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9915997 https://reactome.org/PathwayBrowser/#/R-DDI-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Dictyostelium discoideum 15379 R-ALL-29368 O2 [cytosol] R-DDI-9916401 https://reactome.org/PathwayBrowser/#/R-DDI-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Dictyostelium discoideum 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-1234165 https://reactome.org/PathwayBrowser/#/R-DME-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1234173 https://reactome.org/PathwayBrowser/#/R-DME-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1234177 https://reactome.org/PathwayBrowser/#/R-DME-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-1234181 https://reactome.org/PathwayBrowser/#/R-DME-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1237119 https://reactome.org/PathwayBrowser/#/R-DME-1237119 Acireductone is oxidized to MOB IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-141341 https://reactome.org/PathwayBrowser/#/R-DME-141341 SMOX-3 oxidises SPN to SPM IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-141348 https://reactome.org/PathwayBrowser/#/R-DME-141348 PAO:FAD oxidises NASPM to PTCN IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-141351 https://reactome.org/PathwayBrowser/#/R-DME-141351 PAOX:FAD oxidises NASPN to SPM IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-143468 https://reactome.org/PathwayBrowser/#/R-DME-143468 MEOS oxidizes ethanol to acetaldehyde IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1497810 https://reactome.org/PathwayBrowser/#/R-DME-1497810 Uncoupled eNOS favours the formation of superoxide IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1562626 https://reactome.org/PathwayBrowser/#/R-DME-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-156526 https://reactome.org/PathwayBrowser/#/R-DME-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-1614544 https://reactome.org/PathwayBrowser/#/R-DME-1614544 Sulfite is oxidized to sulfate IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-1614605 https://reactome.org/PathwayBrowser/#/R-DME-1614605 Persulfide sulfur is dioxygenated IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-1614645 https://reactome.org/PathwayBrowser/#/R-DME-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-163214 https://reactome.org/PathwayBrowser/#/R-DME-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-189398 https://reactome.org/PathwayBrowser/#/R-DME-189398 HMOX1 dimer, HMOX2 cleave heme IEA Drosophila melanogaster 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DME-189421 https://reactome.org/PathwayBrowser/#/R-DME-189421 CPO transforms COPRO3 to PPGEN9 IEA Drosophila melanogaster 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DME-189423 https://reactome.org/PathwayBrowser/#/R-DME-189423 PPO oxidises PPGEN9 to PRIN9 IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-192335 https://reactome.org/PathwayBrowser/#/R-DME-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-193060 https://reactome.org/PathwayBrowser/#/R-DME-193060 CYP19A1 hydroxylates ANDST to E1 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-193143 https://reactome.org/PathwayBrowser/#/R-DME-193143 CYP19A1 hydroxylates TEST to EST17b IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-193369 https://reactome.org/PathwayBrowser/#/R-DME-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-1981104 https://reactome.org/PathwayBrowser/#/R-DME-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-202127 https://reactome.org/PathwayBrowser/#/R-DME-202127 eNOS synthesizes NO IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-204662 https://reactome.org/PathwayBrowser/#/R-DME-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-2066787 https://reactome.org/PathwayBrowser/#/R-DME-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-209823 https://reactome.org/PathwayBrowser/#/R-DME-209823 Tyrosine is hydroxylated to dopa IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-209828 https://reactome.org/PathwayBrowser/#/R-DME-209828 Tryptophan is hydroxylated IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-209845 https://reactome.org/PathwayBrowser/#/R-DME-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Drosophila melanogaster 15379 R-ALL-351593 O2 [secretory granule lumen] R-DME-209891 https://reactome.org/PathwayBrowser/#/R-DME-209891 Dopamine is oxidised to noradrenaline IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211874 https://reactome.org/PathwayBrowser/#/R-DME-211874 CYP2S1 4-hydroxylates atRA IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211881 https://reactome.org/PathwayBrowser/#/R-DME-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211910 https://reactome.org/PathwayBrowser/#/R-DME-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211929 https://reactome.org/PathwayBrowser/#/R-DME-211929 CYP2C19 5-hydroxylates omeprazole IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211966 https://reactome.org/PathwayBrowser/#/R-DME-211966 CYP2D6 4-hydroxylates debrisoquine IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211968 https://reactome.org/PathwayBrowser/#/R-DME-211968 CYP2W1 oxidises INDOL IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211983 https://reactome.org/PathwayBrowser/#/R-DME-211983 CYP2J2 oxidises ARA IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211988 https://reactome.org/PathwayBrowser/#/R-DME-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-211991 https://reactome.org/PathwayBrowser/#/R-DME-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-212004 https://reactome.org/PathwayBrowser/#/R-DME-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-212005 https://reactome.org/PathwayBrowser/#/R-DME-212005 CYP2F1 dehydrogenates 3-methylindole IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-2161814 https://reactome.org/PathwayBrowser/#/R-DME-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-2161890 https://reactome.org/PathwayBrowser/#/R-DME-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-2161899 https://reactome.org/PathwayBrowser/#/R-DME-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-2162187 https://reactome.org/PathwayBrowser/#/R-DME-2162187 COQ6 hydroxylates DHB IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-2162194 https://reactome.org/PathwayBrowser/#/R-DME-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-2172678 https://reactome.org/PathwayBrowser/#/R-DME-2172678 PHF8 demethylates histone H4K20me1 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-3204311 https://reactome.org/PathwayBrowser/#/R-DME-3204311 AOX1 oxidises PXL to PDXate IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-3299680 https://reactome.org/PathwayBrowser/#/R-DME-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-3299691 https://reactome.org/PathwayBrowser/#/R-DME-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Drosophila melanogaster 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DME-3341294 https://reactome.org/PathwayBrowser/#/R-DME-3341294 Superoxide reduces cytochrome c IEA Drosophila melanogaster 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DME-3777112 https://reactome.org/PathwayBrowser/#/R-DME-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-389821 https://reactome.org/PathwayBrowser/#/R-DME-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-389842 https://reactome.org/PathwayBrowser/#/R-DME-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-389862 https://reactome.org/PathwayBrowser/#/R-DME-389862 Conversion of glyoxylate to oxalate IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-389889 https://reactome.org/PathwayBrowser/#/R-DME-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-389891 https://reactome.org/PathwayBrowser/#/R-DME-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-390256 https://reactome.org/PathwayBrowser/#/R-DME-390256 ACOX1 oxidizes C26:0 CoA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-418436 https://reactome.org/PathwayBrowser/#/R-DME-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-428259 https://reactome.org/PathwayBrowser/#/R-DME-428259 DEGS1 dehydrogenates dihydroceramide IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-428260 https://reactome.org/PathwayBrowser/#/R-DME-428260 DEGS2 oxygenates dihydroceramide IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-5164399 https://reactome.org/PathwayBrowser/#/R-DME-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-5423647 https://reactome.org/PathwayBrowser/#/R-DME-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-5625797 https://reactome.org/PathwayBrowser/#/R-DME-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-5625848 https://reactome.org/PathwayBrowser/#/R-DME-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-5625870 https://reactome.org/PathwayBrowser/#/R-DME-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-5661124 https://reactome.org/PathwayBrowser/#/R-DME-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-5661125 https://reactome.org/PathwayBrowser/#/R-DME-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-5678327 https://reactome.org/PathwayBrowser/#/R-DME-5678327 MIOX oxidises Ins to GlcA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-5690565 https://reactome.org/PathwayBrowser/#/R-DME-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-5691107 https://reactome.org/PathwayBrowser/#/R-DME-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Drosophila melanogaster 15379 R-ALL-352327 O2 [extracellular region] R-DME-5693681 https://reactome.org/PathwayBrowser/#/R-DME-5693681 DUOX1,2 reduce O2 to H2O2 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-5693761 https://reactome.org/PathwayBrowser/#/R-DME-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-6786239 https://reactome.org/PathwayBrowser/#/R-DME-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-6787811 https://reactome.org/PathwayBrowser/#/R-DME-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-6807557 https://reactome.org/PathwayBrowser/#/R-DME-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-6810076 https://reactome.org/PathwayBrowser/#/R-DME-6810076 DDO oxidizes D-Asp to OA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-6814153 https://reactome.org/PathwayBrowser/#/R-DME-6814153 ADO oxidises 2AET to HTAU IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71118 https://reactome.org/PathwayBrowser/#/R-DME-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71163 https://reactome.org/PathwayBrowser/#/R-DME-71163 HPD dioxygenates HPP IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71164 https://reactome.org/PathwayBrowser/#/R-DME-71164 HGD dioxygenates homogentisate IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71188 https://reactome.org/PathwayBrowser/#/R-DME-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71200 https://reactome.org/PathwayBrowser/#/R-DME-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Drosophila melanogaster 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DME-71241 https://reactome.org/PathwayBrowser/#/R-DME-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-71261 https://reactome.org/PathwayBrowser/#/R-DME-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-74247 https://reactome.org/PathwayBrowser/#/R-DME-74247 XDH oxidizes hypoxanthine to form xanthine IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-74258 https://reactome.org/PathwayBrowser/#/R-DME-74258 XDH oxidizes xanthine to form urate IEA Drosophila melanogaster 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DME-76031 https://reactome.org/PathwayBrowser/#/R-DME-76031 2 H2O2 => O2 + 2 H2O IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76354 https://reactome.org/PathwayBrowser/#/R-DME-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76397 https://reactome.org/PathwayBrowser/#/R-DME-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76416 https://reactome.org/PathwayBrowser/#/R-DME-76416 Benzene is hydroxylated to phenol IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76453 https://reactome.org/PathwayBrowser/#/R-DME-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76456 https://reactome.org/PathwayBrowser/#/R-DME-76456 O-atom dealkylation of dextromethorphan IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-76475 https://reactome.org/PathwayBrowser/#/R-DME-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-8847579 https://reactome.org/PathwayBrowser/#/R-DME-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9027043 https://reactome.org/PathwayBrowser/#/R-DME-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9027302 https://reactome.org/PathwayBrowser/#/R-DME-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9027321 https://reactome.org/PathwayBrowser/#/R-DME-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9629578 https://reactome.org/PathwayBrowser/#/R-DME-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9629591 https://reactome.org/PathwayBrowser/#/R-DME-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9629869 https://reactome.org/PathwayBrowser/#/R-DME-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9629888 https://reactome.org/PathwayBrowser/#/R-DME-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9629946 https://reactome.org/PathwayBrowser/#/R-DME-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-9630022 https://reactome.org/PathwayBrowser/#/R-DME-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-9630769 https://reactome.org/PathwayBrowser/#/R-DME-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Drosophila melanogaster 15379 R-ALL-113685 O2 [nucleoplasm] R-DME-9630993 https://reactome.org/PathwayBrowser/#/R-DME-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-965019 https://reactome.org/PathwayBrowser/#/R-DME-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-965079 https://reactome.org/PathwayBrowser/#/R-DME-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-9749986 https://reactome.org/PathwayBrowser/#/R-DME-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-9750016 https://reactome.org/PathwayBrowser/#/R-DME-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9753285 https://reactome.org/PathwayBrowser/#/R-DME-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-975635 https://reactome.org/PathwayBrowser/#/R-DME-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Drosophila melanogaster 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DME-9817575 https://reactome.org/PathwayBrowser/#/R-DME-9817575 ERO1B oxidizes P4HB IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9915971 https://reactome.org/PathwayBrowser/#/R-DME-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DME-9915997 https://reactome.org/PathwayBrowser/#/R-DME-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Drosophila melanogaster 15379 R-ALL-29368 O2 [cytosol] R-DRE-1222376 https://reactome.org/PathwayBrowser/#/R-DRE-1222376 NOX2 generates superoxide from oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1234164 https://reactome.org/PathwayBrowser/#/R-DRE-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-1234165 https://reactome.org/PathwayBrowser/#/R-DRE-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-1234181 https://reactome.org/PathwayBrowser/#/R-DRE-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Danio rerio 15379 R-ALL-1236709 O2 [phagolysosome] R-DRE-1236967 https://reactome.org/PathwayBrowser/#/R-DRE-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1237119 https://reactome.org/PathwayBrowser/#/R-DRE-1237119 Acireductone is oxidized to MOB IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1237325 https://reactome.org/PathwayBrowser/#/R-DRE-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1247668 https://reactome.org/PathwayBrowser/#/R-DRE-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-139970 https://reactome.org/PathwayBrowser/#/R-DRE-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-140355 https://reactome.org/PathwayBrowser/#/R-DRE-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-141200 https://reactome.org/PathwayBrowser/#/R-DRE-141200 MAOB:FAD oxidatively deaminates of PEA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-141202 https://reactome.org/PathwayBrowser/#/R-DRE-141202 MAOB:FAD oxidatively deaminates TYR IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-141348 https://reactome.org/PathwayBrowser/#/R-DRE-141348 PAO:FAD oxidises NASPM to PTCN IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-141351 https://reactome.org/PathwayBrowser/#/R-DRE-141351 PAOX:FAD oxidises NASPN to SPM IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-143468 https://reactome.org/PathwayBrowser/#/R-DRE-143468 MEOS oxidizes ethanol to acetaldehyde IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1562626 https://reactome.org/PathwayBrowser/#/R-DRE-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-156526 https://reactome.org/PathwayBrowser/#/R-DRE-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-1614605 https://reactome.org/PathwayBrowser/#/R-DRE-1614605 Persulfide sulfur is dioxygenated IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1614645 https://reactome.org/PathwayBrowser/#/R-DRE-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-163214 https://reactome.org/PathwayBrowser/#/R-DRE-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-1650808 https://reactome.org/PathwayBrowser/#/R-DRE-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-1655453 https://reactome.org/PathwayBrowser/#/R-DRE-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-189398 https://reactome.org/PathwayBrowser/#/R-DRE-189398 HMOX1 dimer, HMOX2 cleave heme IEA Danio rerio 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DRE-189421 https://reactome.org/PathwayBrowser/#/R-DRE-189421 CPO transforms COPRO3 to PPGEN9 IEA Danio rerio 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DRE-189423 https://reactome.org/PathwayBrowser/#/R-DRE-189423 PPO oxidises PPGEN9 to PRIN9 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-191299 https://reactome.org/PathwayBrowser/#/R-DRE-191299 Squalene is oxidized to its epoxide IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-191983 https://reactome.org/PathwayBrowser/#/R-DRE-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-192061 https://reactome.org/PathwayBrowser/#/R-DRE-192061 CYP46A1 24-hydroxylates CHOL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-192157 https://reactome.org/PathwayBrowser/#/R-DRE-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-193054 https://reactome.org/PathwayBrowser/#/R-DRE-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193060 https://reactome.org/PathwayBrowser/#/R-DRE-193060 CYP19A1 hydroxylates ANDST to E1 IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-193065 https://reactome.org/PathwayBrowser/#/R-DRE-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193068 https://reactome.org/PathwayBrowser/#/R-DRE-193068 CYP17A1 17-hydroxylates PREG IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193070 https://reactome.org/PathwayBrowser/#/R-DRE-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193072 https://reactome.org/PathwayBrowser/#/R-DRE-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193099 https://reactome.org/PathwayBrowser/#/R-DRE-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-193101 https://reactome.org/PathwayBrowser/#/R-DRE-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193143 https://reactome.org/PathwayBrowser/#/R-DRE-193143 CYP19A1 hydroxylates TEST to EST17b IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193709 https://reactome.org/PathwayBrowser/#/R-DRE-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-193845 https://reactome.org/PathwayBrowser/#/R-DRE-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-194641 https://reactome.org/PathwayBrowser/#/R-DRE-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-194669 https://reactome.org/PathwayBrowser/#/R-DRE-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-194678 https://reactome.org/PathwayBrowser/#/R-DRE-194678 CYP51A1 demethylates LNSOL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-195664 https://reactome.org/PathwayBrowser/#/R-DRE-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-1981104 https://reactome.org/PathwayBrowser/#/R-DRE-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-2002466 https://reactome.org/PathwayBrowser/#/R-DRE-2002466 Formation of allysine by LOX IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2046084 https://reactome.org/PathwayBrowser/#/R-DRE-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2046096 https://reactome.org/PathwayBrowser/#/R-DRE-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2046097 https://reactome.org/PathwayBrowser/#/R-DRE-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-204662 https://reactome.org/PathwayBrowser/#/R-DRE-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-2066787 https://reactome.org/PathwayBrowser/#/R-DRE-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-209765 https://reactome.org/PathwayBrowser/#/R-DRE-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-209823 https://reactome.org/PathwayBrowser/#/R-DRE-209823 Tyrosine is hydroxylated to dopa IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-209828 https://reactome.org/PathwayBrowser/#/R-DRE-209828 Tryptophan is hydroxylated IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-209868 https://reactome.org/PathwayBrowser/#/R-DRE-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Danio rerio 15379 R-ALL-351593 O2 [secretory granule lumen] R-DRE-209891 https://reactome.org/PathwayBrowser/#/R-DRE-209891 Dopamine is oxidised to noradrenaline IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-211873 https://reactome.org/PathwayBrowser/#/R-DRE-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211874 https://reactome.org/PathwayBrowser/#/R-DRE-211874 CYP2S1 4-hydroxylates atRA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211881 https://reactome.org/PathwayBrowser/#/R-DRE-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211882 https://reactome.org/PathwayBrowser/#/R-DRE-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211904 https://reactome.org/PathwayBrowser/#/R-DRE-211904 CYP4F12 18-hydroxylates ARA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211919 https://reactome.org/PathwayBrowser/#/R-DRE-211919 CYP4F8 19-hydroxylates PGH2 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-211923 https://reactome.org/PathwayBrowser/#/R-DRE-211923 CYP26C1 4-hydroxylates 9cRA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211948 https://reactome.org/PathwayBrowser/#/R-DRE-211948 CYP3A4 can N-demethylate loperamide IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-211950 https://reactome.org/PathwayBrowser/#/R-DRE-211950 CYP24A1 24-hydroxylates CTL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-211951 https://reactome.org/PathwayBrowser/#/R-DRE-211951 CYP1B1 4-hydroxylates EST17b IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211959 https://reactome.org/PathwayBrowser/#/R-DRE-211959 CYP3A43 6b-hydroxylates TEST IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211962 https://reactome.org/PathwayBrowser/#/R-DRE-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211966 https://reactome.org/PathwayBrowser/#/R-DRE-211966 CYP2D6 4-hydroxylates debrisoquine IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211968 https://reactome.org/PathwayBrowser/#/R-DRE-211968 CYP2W1 oxidises INDOL IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211983 https://reactome.org/PathwayBrowser/#/R-DRE-211983 CYP2J2 oxidises ARA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-211991 https://reactome.org/PathwayBrowser/#/R-DRE-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-212005 https://reactome.org/PathwayBrowser/#/R-DRE-212005 CYP2F1 dehydrogenates 3-methylindole IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-212007 https://reactome.org/PathwayBrowser/#/R-DRE-212007 CYP26A1,B1 4-hydroxylate atRA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-213175 https://reactome.org/PathwayBrowser/#/R-DRE-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-215526 https://reactome.org/PathwayBrowser/#/R-DRE-215526 CYP4F3 20-hydroxylates LTB4 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161745 https://reactome.org/PathwayBrowser/#/R-DRE-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161775 https://reactome.org/PathwayBrowser/#/R-DRE-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161792 https://reactome.org/PathwayBrowser/#/R-DRE-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161794 https://reactome.org/PathwayBrowser/#/R-DRE-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2161795 https://reactome.org/PathwayBrowser/#/R-DRE-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2161814 https://reactome.org/PathwayBrowser/#/R-DRE-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161890 https://reactome.org/PathwayBrowser/#/R-DRE-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161899 https://reactome.org/PathwayBrowser/#/R-DRE-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2161940 https://reactome.org/PathwayBrowser/#/R-DRE-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161950 https://reactome.org/PathwayBrowser/#/R-DRE-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161951 https://reactome.org/PathwayBrowser/#/R-DRE-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2161964 https://reactome.org/PathwayBrowser/#/R-DRE-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-2162002 https://reactome.org/PathwayBrowser/#/R-DRE-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-2162187 https://reactome.org/PathwayBrowser/#/R-DRE-2162187 COQ6 hydroxylates DHB IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-2162194 https://reactome.org/PathwayBrowser/#/R-DRE-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-2168885 https://reactome.org/PathwayBrowser/#/R-DRE-2168885 Haptoglobin binds Hemoglobin IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-217255 https://reactome.org/PathwayBrowser/#/R-DRE-217255 FMO1:FAD N-oxidises TAM IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-217258 https://reactome.org/PathwayBrowser/#/R-DRE-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-2172678 https://reactome.org/PathwayBrowser/#/R-DRE-2172678 PHF8 demethylates histone H4K20me1 IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-2230938 https://reactome.org/PathwayBrowser/#/R-DRE-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Danio rerio 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-DRE-2230938 https://reactome.org/PathwayBrowser/#/R-DRE-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-2309787 https://reactome.org/PathwayBrowser/#/R-DRE-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-2395340 https://reactome.org/PathwayBrowser/#/R-DRE-2395340 Formation of hydroxyallysine by LOX IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-3204311 https://reactome.org/PathwayBrowser/#/R-DRE-3204311 AOX1 oxidises PXL to PDXate IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-3299680 https://reactome.org/PathwayBrowser/#/R-DRE-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-3299682 https://reactome.org/PathwayBrowser/#/R-DRE-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-3299691 https://reactome.org/PathwayBrowser/#/R-DRE-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Danio rerio 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DRE-3341294 https://reactome.org/PathwayBrowser/#/R-DRE-3341294 Superoxide reduces cytochrome c IEA Danio rerio 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-DRE-3777112 https://reactome.org/PathwayBrowser/#/R-DRE-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-389639 https://reactome.org/PathwayBrowser/#/R-DRE-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-389821 https://reactome.org/PathwayBrowser/#/R-DRE-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-389842 https://reactome.org/PathwayBrowser/#/R-DRE-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-389862 https://reactome.org/PathwayBrowser/#/R-DRE-389862 Conversion of glyoxylate to oxalate IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-389891 https://reactome.org/PathwayBrowser/#/R-DRE-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-390256 https://reactome.org/PathwayBrowser/#/R-DRE-390256 ACOX1 oxidizes C26:0 CoA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-418436 https://reactome.org/PathwayBrowser/#/R-DRE-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-428259 https://reactome.org/PathwayBrowser/#/R-DRE-428259 DEGS1 dehydrogenates dihydroceramide IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-5164399 https://reactome.org/PathwayBrowser/#/R-DRE-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-5218841 https://reactome.org/PathwayBrowser/#/R-DRE-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5340214 https://reactome.org/PathwayBrowser/#/R-DRE-5340214 CYGB binds O2 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5340226 https://reactome.org/PathwayBrowser/#/R-DRE-5340226 CYGB dioxygenates NO IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5362525 https://reactome.org/PathwayBrowser/#/R-DRE-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-5423117 https://reactome.org/PathwayBrowser/#/R-DRE-5423117 PHF8 demethylates MeK21-histone H4 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5423647 https://reactome.org/PathwayBrowser/#/R-DRE-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5423664 https://reactome.org/PathwayBrowser/#/R-DRE-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5423672 https://reactome.org/PathwayBrowser/#/R-DRE-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5423678 https://reactome.org/PathwayBrowser/#/R-DRE-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5602295 https://reactome.org/PathwayBrowser/#/R-DRE-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-5625797 https://reactome.org/PathwayBrowser/#/R-DRE-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-5625848 https://reactome.org/PathwayBrowser/#/R-DRE-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-5661124 https://reactome.org/PathwayBrowser/#/R-DRE-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-5661125 https://reactome.org/PathwayBrowser/#/R-DRE-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Danio rerio 15379 R-ALL-1236709 O2 [phagolysosome] R-DRE-5668629 https://reactome.org/PathwayBrowser/#/R-DRE-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-5668718 https://reactome.org/PathwayBrowser/#/R-DRE-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-5668731 https://reactome.org/PathwayBrowser/#/R-DRE-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5678327 https://reactome.org/PathwayBrowser/#/R-DRE-5678327 MIOX oxidises Ins to GlcA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5690565 https://reactome.org/PathwayBrowser/#/R-DRE-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-5691107 https://reactome.org/PathwayBrowser/#/R-DRE-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-5696119 https://reactome.org/PathwayBrowser/#/R-DRE-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-5696131 https://reactome.org/PathwayBrowser/#/R-DRE-5696131 AOC1 deaminates Hist IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-6786239 https://reactome.org/PathwayBrowser/#/R-DRE-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Danio rerio 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-DRE-6789092 https://reactome.org/PathwayBrowser/#/R-DRE-6789092 NOX2 generates superoxide anion from oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-6807053 https://reactome.org/PathwayBrowser/#/R-DRE-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-6814153 https://reactome.org/PathwayBrowser/#/R-DRE-6814153 ADO oxidises 2AET to HTAU IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71118 https://reactome.org/PathwayBrowser/#/R-DRE-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71163 https://reactome.org/PathwayBrowser/#/R-DRE-71163 HPD dioxygenates HPP IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71164 https://reactome.org/PathwayBrowser/#/R-DRE-71164 HGD dioxygenates homogentisate IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71188 https://reactome.org/PathwayBrowser/#/R-DRE-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71200 https://reactome.org/PathwayBrowser/#/R-DRE-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71218 https://reactome.org/PathwayBrowser/#/R-DRE-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-71261 https://reactome.org/PathwayBrowser/#/R-DRE-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Danio rerio 15379 R-ALL-113535 O2 [peroxisomal matrix] R-DRE-76031 https://reactome.org/PathwayBrowser/#/R-DRE-76031 2 H2O2 => O2 + 2 H2O IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76354 https://reactome.org/PathwayBrowser/#/R-DRE-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76373 https://reactome.org/PathwayBrowser/#/R-DRE-76373 N-hydroxylation of 4-aminobiphenyl IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76386 https://reactome.org/PathwayBrowser/#/R-DRE-76386 CYP1A2 S-demethylates 6MMP IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76397 https://reactome.org/PathwayBrowser/#/R-DRE-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76416 https://reactome.org/PathwayBrowser/#/R-DRE-76416 Benzene is hydroxylated to phenol IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76426 https://reactome.org/PathwayBrowser/#/R-DRE-76426 N-atom dealkylation of caffeine IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76453 https://reactome.org/PathwayBrowser/#/R-DRE-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76456 https://reactome.org/PathwayBrowser/#/R-DRE-76456 O-atom dealkylation of dextromethorphan IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76472 https://reactome.org/PathwayBrowser/#/R-DRE-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-76475 https://reactome.org/PathwayBrowser/#/R-DRE-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8865107 https://reactome.org/PathwayBrowser/#/R-DRE-8865107 MICAL1 produces NADP+, H2O2 IEA Danio rerio 15379 R-ALL-5668566 O2 [melanosome lumen] R-DRE-8878581 https://reactome.org/PathwayBrowser/#/R-DRE-8878581 TYRP1 oxidises DHICA to IQCA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-888614 https://reactome.org/PathwayBrowser/#/R-DRE-888614 IDO2 dioxygenates L-Trp to NFK IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-8956458 https://reactome.org/PathwayBrowser/#/R-DRE-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8981606 https://reactome.org/PathwayBrowser/#/R-DRE-8981606 Myoglobin binds oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8981610 https://reactome.org/PathwayBrowser/#/R-DRE-8981610 Neuroglobin binds oxygen IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8981621 https://reactome.org/PathwayBrowser/#/R-DRE-8981621 Neuroglobin:oxygen dissociates IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8981622 https://reactome.org/PathwayBrowser/#/R-DRE-8981622 Myoglobin:oxygen dissociates IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-8982617 https://reactome.org/PathwayBrowser/#/R-DRE-8982617 CYGB:O2 dissociates IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018858 https://reactome.org/PathwayBrowser/#/R-DRE-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018859 https://reactome.org/PathwayBrowser/#/R-DRE-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018863 https://reactome.org/PathwayBrowser/#/R-DRE-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018880 https://reactome.org/PathwayBrowser/#/R-DRE-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018894 https://reactome.org/PathwayBrowser/#/R-DRE-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9018907 https://reactome.org/PathwayBrowser/#/R-DRE-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020251 https://reactome.org/PathwayBrowser/#/R-DRE-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020259 https://reactome.org/PathwayBrowser/#/R-DRE-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020261 https://reactome.org/PathwayBrowser/#/R-DRE-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020264 https://reactome.org/PathwayBrowser/#/R-DRE-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020274 https://reactome.org/PathwayBrowser/#/R-DRE-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020275 https://reactome.org/PathwayBrowser/#/R-DRE-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020282 https://reactome.org/PathwayBrowser/#/R-DRE-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9020610 https://reactome.org/PathwayBrowser/#/R-DRE-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9024872 https://reactome.org/PathwayBrowser/#/R-DRE-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9024997 https://reactome.org/PathwayBrowser/#/R-DRE-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9025152 https://reactome.org/PathwayBrowser/#/R-DRE-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9025957 https://reactome.org/PathwayBrowser/#/R-DRE-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9025996 https://reactome.org/PathwayBrowser/#/R-DRE-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9026003 https://reactome.org/PathwayBrowser/#/R-DRE-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9026005 https://reactome.org/PathwayBrowser/#/R-DRE-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9026006 https://reactome.org/PathwayBrowser/#/R-DRE-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9026405 https://reactome.org/PathwayBrowser/#/R-DRE-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9026408 https://reactome.org/PathwayBrowser/#/R-DRE-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027043 https://reactome.org/PathwayBrowser/#/R-DRE-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027302 https://reactome.org/PathwayBrowser/#/R-DRE-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027321 https://reactome.org/PathwayBrowser/#/R-DRE-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027532 https://reactome.org/PathwayBrowser/#/R-DRE-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027607 https://reactome.org/PathwayBrowser/#/R-DRE-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027624 https://reactome.org/PathwayBrowser/#/R-DRE-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027627 https://reactome.org/PathwayBrowser/#/R-DRE-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027628 https://reactome.org/PathwayBrowser/#/R-DRE-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9027633 https://reactome.org/PathwayBrowser/#/R-DRE-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9028255 https://reactome.org/PathwayBrowser/#/R-DRE-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9037761 https://reactome.org/PathwayBrowser/#/R-DRE-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-917891 https://reactome.org/PathwayBrowser/#/R-DRE-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9629591 https://reactome.org/PathwayBrowser/#/R-DRE-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9629869 https://reactome.org/PathwayBrowser/#/R-DRE-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9629946 https://reactome.org/PathwayBrowser/#/R-DRE-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Danio rerio 15379 R-ALL-113685 O2 [nucleoplasm] R-DRE-9630993 https://reactome.org/PathwayBrowser/#/R-DRE-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Danio rerio 15379 R-ALL-352327 O2 [extracellular region] R-DRE-9709360 https://reactome.org/PathwayBrowser/#/R-DRE-9709360 H2O2 reduces MetHb IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-9749986 https://reactome.org/PathwayBrowser/#/R-DRE-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-9750016 https://reactome.org/PathwayBrowser/#/R-DRE-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9753285 https://reactome.org/PathwayBrowser/#/R-DRE-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9756138 https://reactome.org/PathwayBrowser/#/R-DRE-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9756162 https://reactome.org/PathwayBrowser/#/R-DRE-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9756169 https://reactome.org/PathwayBrowser/#/R-DRE-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9756180 https://reactome.org/PathwayBrowser/#/R-DRE-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-975635 https://reactome.org/PathwayBrowser/#/R-DRE-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9758674 https://reactome.org/PathwayBrowser/#/R-DRE-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Danio rerio 15379 R-ALL-113533 O2 [mitochondrial matrix] R-DRE-9856718 https://reactome.org/PathwayBrowser/#/R-DRE-9856718 HPDL dioxygenates HPPA IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9915971 https://reactome.org/PathwayBrowser/#/R-DRE-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-9915992 https://reactome.org/PathwayBrowser/#/R-DRE-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Danio rerio 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-DRE-9915993 https://reactome.org/PathwayBrowser/#/R-DRE-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9915997 https://reactome.org/PathwayBrowser/#/R-DRE-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-DRE-9916401 https://reactome.org/PathwayBrowser/#/R-DRE-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Danio rerio 15379 R-ALL-29368 O2 [cytosol] R-GGA-1222376 https://reactome.org/PathwayBrowser/#/R-GGA-1222376 NOX2 generates superoxide from oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1234164 https://reactome.org/PathwayBrowser/#/R-GGA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-1234165 https://reactome.org/PathwayBrowser/#/R-GGA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1234173 https://reactome.org/PathwayBrowser/#/R-GGA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1234177 https://reactome.org/PathwayBrowser/#/R-GGA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-1234181 https://reactome.org/PathwayBrowser/#/R-GGA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Gallus gallus 15379 R-ALL-1236709 O2 [phagolysosome] R-GGA-1236967 https://reactome.org/PathwayBrowser/#/R-GGA-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1237119 https://reactome.org/PathwayBrowser/#/R-GGA-1237119 Acireductone is oxidized to MOB IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1237325 https://reactome.org/PathwayBrowser/#/R-GGA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1247668 https://reactome.org/PathwayBrowser/#/R-GGA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-139970 https://reactome.org/PathwayBrowser/#/R-GGA-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-140355 https://reactome.org/PathwayBrowser/#/R-GGA-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-141186 https://reactome.org/PathwayBrowser/#/R-GGA-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-141200 https://reactome.org/PathwayBrowser/#/R-GGA-141200 MAOB:FAD oxidatively deaminates of PEA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-141202 https://reactome.org/PathwayBrowser/#/R-GGA-141202 MAOB:FAD oxidatively deaminates TYR IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-141341 https://reactome.org/PathwayBrowser/#/R-GGA-141341 SMOX-3 oxidises SPN to SPM IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-141348 https://reactome.org/PathwayBrowser/#/R-GGA-141348 PAO:FAD oxidises NASPM to PTCN IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-141351 https://reactome.org/PathwayBrowser/#/R-GGA-141351 PAOX:FAD oxidises NASPN to SPM IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-143468 https://reactome.org/PathwayBrowser/#/R-GGA-143468 MEOS oxidizes ethanol to acetaldehyde IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1497810 https://reactome.org/PathwayBrowser/#/R-GGA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1562626 https://reactome.org/PathwayBrowser/#/R-GGA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-156526 https://reactome.org/PathwayBrowser/#/R-GGA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-1614544 https://reactome.org/PathwayBrowser/#/R-GGA-1614544 Sulfite is oxidized to sulfate IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-1614645 https://reactome.org/PathwayBrowser/#/R-GGA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-163214 https://reactome.org/PathwayBrowser/#/R-GGA-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-1650808 https://reactome.org/PathwayBrowser/#/R-GGA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-189398 https://reactome.org/PathwayBrowser/#/R-GGA-189398 HMOX1 dimer, HMOX2 cleave heme IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-189421 https://reactome.org/PathwayBrowser/#/R-GGA-189421 CPO transforms COPRO3 to PPGEN9 IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-189423 https://reactome.org/PathwayBrowser/#/R-GGA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-191299 https://reactome.org/PathwayBrowser/#/R-GGA-191299 Squalene is oxidized to its epoxide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-191972 https://reactome.org/PathwayBrowser/#/R-GGA-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-191983 https://reactome.org/PathwayBrowser/#/R-GGA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-192051 https://reactome.org/PathwayBrowser/#/R-GGA-192051 CYP7A1 7-hydroxylates CHOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-192061 https://reactome.org/PathwayBrowser/#/R-GGA-192061 CYP46A1 24-hydroxylates CHOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-192065 https://reactome.org/PathwayBrowser/#/R-GGA-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-192178 https://reactome.org/PathwayBrowser/#/R-GGA-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-192335 https://reactome.org/PathwayBrowser/#/R-GGA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-193054 https://reactome.org/PathwayBrowser/#/R-GGA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193060 https://reactome.org/PathwayBrowser/#/R-GGA-193060 CYP19A1 hydroxylates ANDST to E1 IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-193065 https://reactome.org/PathwayBrowser/#/R-GGA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193068 https://reactome.org/PathwayBrowser/#/R-GGA-193068 CYP17A1 17-hydroxylates PREG IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193070 https://reactome.org/PathwayBrowser/#/R-GGA-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193072 https://reactome.org/PathwayBrowser/#/R-GGA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193099 https://reactome.org/PathwayBrowser/#/R-GGA-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-193101 https://reactome.org/PathwayBrowser/#/R-GGA-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193143 https://reactome.org/PathwayBrowser/#/R-GGA-193143 CYP19A1 hydroxylates TEST to EST17b IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-193369 https://reactome.org/PathwayBrowser/#/R-GGA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193964 https://reactome.org/PathwayBrowser/#/R-GGA-193964 CYP21A2 21-hydroxylates PROG IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-193981 https://reactome.org/PathwayBrowser/#/R-GGA-193981 CYP21A2 oxidises 17HPROG IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-194641 https://reactome.org/PathwayBrowser/#/R-GGA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-194669 https://reactome.org/PathwayBrowser/#/R-GGA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-194678 https://reactome.org/PathwayBrowser/#/R-GGA-194678 CYP51A1 demethylates LNSOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-195664 https://reactome.org/PathwayBrowser/#/R-GGA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-1980233 https://reactome.org/PathwayBrowser/#/R-GGA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-1981104 https://reactome.org/PathwayBrowser/#/R-GGA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-2002466 https://reactome.org/PathwayBrowser/#/R-GGA-2002466 Formation of allysine by LOX IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-202127 https://reactome.org/PathwayBrowser/#/R-GGA-202127 eNOS synthesizes NO IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2046084 https://reactome.org/PathwayBrowser/#/R-GGA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2046089 https://reactome.org/PathwayBrowser/#/R-GGA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2046092 https://reactome.org/PathwayBrowser/#/R-GGA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2046096 https://reactome.org/PathwayBrowser/#/R-GGA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2046097 https://reactome.org/PathwayBrowser/#/R-GGA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-204662 https://reactome.org/PathwayBrowser/#/R-GGA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-2066787 https://reactome.org/PathwayBrowser/#/R-GGA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-209823 https://reactome.org/PathwayBrowser/#/R-GGA-209823 Tyrosine is hydroxylated to dopa IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-209828 https://reactome.org/PathwayBrowser/#/R-GGA-209828 Tryptophan is hydroxylated IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-209845 https://reactome.org/PathwayBrowser/#/R-GGA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Gallus gallus 15379 R-ALL-351593 O2 [secretory granule lumen] R-GGA-209891 https://reactome.org/PathwayBrowser/#/R-GGA-209891 Dopamine is oxidised to noradrenaline IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211874 https://reactome.org/PathwayBrowser/#/R-GGA-211874 CYP2S1 4-hydroxylates atRA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211882 https://reactome.org/PathwayBrowser/#/R-GGA-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211910 https://reactome.org/PathwayBrowser/#/R-GGA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-211923 https://reactome.org/PathwayBrowser/#/R-GGA-211923 CYP26C1 4-hydroxylates 9cRA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211924 https://reactome.org/PathwayBrowser/#/R-GGA-211924 CYP4B1 12-hydroxylates ARA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211929 https://reactome.org/PathwayBrowser/#/R-GGA-211929 CYP2C19 5-hydroxylates omeprazole IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211948 https://reactome.org/PathwayBrowser/#/R-GGA-211948 CYP3A4 can N-demethylate loperamide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-211951 https://reactome.org/PathwayBrowser/#/R-GGA-211951 CYP1B1 4-hydroxylates EST17b IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211959 https://reactome.org/PathwayBrowser/#/R-GGA-211959 CYP3A43 6b-hydroxylates TEST IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211960 https://reactome.org/PathwayBrowser/#/R-GGA-211960 CYP2U1 19-hydroxylates ARA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211966 https://reactome.org/PathwayBrowser/#/R-GGA-211966 CYP2D6 4-hydroxylates debrisoquine IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211968 https://reactome.org/PathwayBrowser/#/R-GGA-211968 CYP2W1 oxidises INDOL IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211983 https://reactome.org/PathwayBrowser/#/R-GGA-211983 CYP2J2 oxidises ARA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211988 https://reactome.org/PathwayBrowser/#/R-GGA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-211991 https://reactome.org/PathwayBrowser/#/R-GGA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-212004 https://reactome.org/PathwayBrowser/#/R-GGA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-212007 https://reactome.org/PathwayBrowser/#/R-GGA-212007 CYP26A1,B1 4-hydroxylate atRA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-213175 https://reactome.org/PathwayBrowser/#/R-GGA-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2161795 https://reactome.org/PathwayBrowser/#/R-GGA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2161814 https://reactome.org/PathwayBrowser/#/R-GGA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161890 https://reactome.org/PathwayBrowser/#/R-GGA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161899 https://reactome.org/PathwayBrowser/#/R-GGA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161907 https://reactome.org/PathwayBrowser/#/R-GGA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161917 https://reactome.org/PathwayBrowser/#/R-GGA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2161940 https://reactome.org/PathwayBrowser/#/R-GGA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161950 https://reactome.org/PathwayBrowser/#/R-GGA-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2161951 https://reactome.org/PathwayBrowser/#/R-GGA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-2162002 https://reactome.org/PathwayBrowser/#/R-GGA-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-2162187 https://reactome.org/PathwayBrowser/#/R-GGA-2162187 COQ6 hydroxylates DHB IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-2162194 https://reactome.org/PathwayBrowser/#/R-GGA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-2168885 https://reactome.org/PathwayBrowser/#/R-GGA-2168885 Haptoglobin binds Hemoglobin IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-2172678 https://reactome.org/PathwayBrowser/#/R-GGA-2172678 PHF8 demethylates histone H4K20me1 IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-2230938 https://reactome.org/PathwayBrowser/#/R-GGA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Gallus gallus 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-GGA-2230938 https://reactome.org/PathwayBrowser/#/R-GGA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-2309787 https://reactome.org/PathwayBrowser/#/R-GGA-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-2395340 https://reactome.org/PathwayBrowser/#/R-GGA-2395340 Formation of hydroxyallysine by LOX IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-265296 https://reactome.org/PathwayBrowser/#/R-GGA-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-3204311 https://reactome.org/PathwayBrowser/#/R-GGA-3204311 AOX1 oxidises PXL to PDXate IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-3299680 https://reactome.org/PathwayBrowser/#/R-GGA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-3299682 https://reactome.org/PathwayBrowser/#/R-GGA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-3299691 https://reactome.org/PathwayBrowser/#/R-GGA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-3341294 https://reactome.org/PathwayBrowser/#/R-GGA-3341294 Superoxide reduces cytochrome c IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-353356 https://reactome.org/PathwayBrowser/#/R-GGA-353356 Reversal of Alkylation Damage By DNA Dioxygenases TAS Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-374909 https://reactome.org/PathwayBrowser/#/R-GGA-374909 Catabolism of Noradrenaline IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-3777112 https://reactome.org/PathwayBrowser/#/R-GGA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-379382 https://reactome.org/PathwayBrowser/#/R-GGA-379382 MAOA:FAD deaminates DA to DOPAC IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-379395 https://reactome.org/PathwayBrowser/#/R-GGA-379395 MAOA:FAD deaminates 3MT to HVA IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389639 https://reactome.org/PathwayBrowser/#/R-GGA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389821 https://reactome.org/PathwayBrowser/#/R-GGA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389842 https://reactome.org/PathwayBrowser/#/R-GGA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389862 https://reactome.org/PathwayBrowser/#/R-GGA-389862 Conversion of glyoxylate to oxalate IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389889 https://reactome.org/PathwayBrowser/#/R-GGA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-389891 https://reactome.org/PathwayBrowser/#/R-GGA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-390256 https://reactome.org/PathwayBrowser/#/R-GGA-390256 ACOX1 oxidizes C26:0 CoA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-418436 https://reactome.org/PathwayBrowser/#/R-GGA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-421452 https://reactome.org/PathwayBrowser/#/R-GGA-421452 2 protoporphyrinogen IX + 3 O2 => 2 protoporphyrin IX + 6 H2O IEA Gallus gallus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-GGA-421478 https://reactome.org/PathwayBrowser/#/R-GGA-421478 coproporphyrinogen III + 2 O2 => protoporphyrinogen IX + 2 H2O2 + 2 CO2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-428259 https://reactome.org/PathwayBrowser/#/R-GGA-428259 DEGS1 dehydrogenates dihydroceramide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-428260 https://reactome.org/PathwayBrowser/#/R-GGA-428260 DEGS2 oxygenates dihydroceramide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-433593 https://reactome.org/PathwayBrowser/#/R-GGA-433593 dihydroceramide + NADPH + H+ + O2 => phytoceramide + NADP+ + H2O IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-433599 https://reactome.org/PathwayBrowser/#/R-GGA-433599 dihydroceramide + NAD(P)H + H+ + O2 => ceramide + NAD(P)+ + H2O IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-5164399 https://reactome.org/PathwayBrowser/#/R-GGA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5218841 https://reactome.org/PathwayBrowser/#/R-GGA-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5340214 https://reactome.org/PathwayBrowser/#/R-GGA-5340214 CYGB binds O2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5340226 https://reactome.org/PathwayBrowser/#/R-GGA-5340226 CYGB dioxygenates NO IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5362525 https://reactome.org/PathwayBrowser/#/R-GGA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5423664 https://reactome.org/PathwayBrowser/#/R-GGA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5423672 https://reactome.org/PathwayBrowser/#/R-GGA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5423678 https://reactome.org/PathwayBrowser/#/R-GGA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-5625797 https://reactome.org/PathwayBrowser/#/R-GGA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-5625848 https://reactome.org/PathwayBrowser/#/R-GGA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-5625870 https://reactome.org/PathwayBrowser/#/R-GGA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-5661124 https://reactome.org/PathwayBrowser/#/R-GGA-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-5661125 https://reactome.org/PathwayBrowser/#/R-GGA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Gallus gallus 15379 R-ALL-5668566 O2 [melanosome lumen] R-GGA-5662692 https://reactome.org/PathwayBrowser/#/R-GGA-5662692 Dopa is oxidized to dopaquinone by TYR IEA Gallus gallus 15379 R-ALL-1236709 O2 [phagolysosome] R-GGA-5668629 https://reactome.org/PathwayBrowser/#/R-GGA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5668718 https://reactome.org/PathwayBrowser/#/R-GGA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5668731 https://reactome.org/PathwayBrowser/#/R-GGA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5678327 https://reactome.org/PathwayBrowser/#/R-GGA-5678327 MIOX oxidises Ins to GlcA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5690565 https://reactome.org/PathwayBrowser/#/R-GGA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-5691107 https://reactome.org/PathwayBrowser/#/R-GGA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5693681 https://reactome.org/PathwayBrowser/#/R-GGA-5693681 DUOX1,2 reduce O2 to H2O2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5693761 https://reactome.org/PathwayBrowser/#/R-GGA-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-5696119 https://reactome.org/PathwayBrowser/#/R-GGA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5696131 https://reactome.org/PathwayBrowser/#/R-GGA-5696131 AOC1 deaminates Hist IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5696146 https://reactome.org/PathwayBrowser/#/R-GGA-5696146 AOC2 deaminates TYR IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-5696183 https://reactome.org/PathwayBrowser/#/R-GGA-5696183 AOC3 deaminates BZAM IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-6783880 https://reactome.org/PathwayBrowser/#/R-GGA-6783880 PIPOX oxidises PPCA to P6C IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-6786239 https://reactome.org/PathwayBrowser/#/R-GGA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-6787811 https://reactome.org/PathwayBrowser/#/R-GGA-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Gallus gallus 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-GGA-6789092 https://reactome.org/PathwayBrowser/#/R-GGA-6789092 NOX2 generates superoxide anion from oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-6807053 https://reactome.org/PathwayBrowser/#/R-GGA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-6807557 https://reactome.org/PathwayBrowser/#/R-GGA-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-6810076 https://reactome.org/PathwayBrowser/#/R-GGA-6810076 DDO oxidizes D-Asp to OA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71118 https://reactome.org/PathwayBrowser/#/R-GGA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71163 https://reactome.org/PathwayBrowser/#/R-GGA-71163 HPD dioxygenates HPP IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71164 https://reactome.org/PathwayBrowser/#/R-GGA-71164 HGD dioxygenates homogentisate IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71188 https://reactome.org/PathwayBrowser/#/R-GGA-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71200 https://reactome.org/PathwayBrowser/#/R-GGA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71218 https://reactome.org/PathwayBrowser/#/R-GGA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-71241 https://reactome.org/PathwayBrowser/#/R-GGA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-71261 https://reactome.org/PathwayBrowser/#/R-GGA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-74247 https://reactome.org/PathwayBrowser/#/R-GGA-74247 XDH oxidizes hypoxanthine to form xanthine IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-74258 https://reactome.org/PathwayBrowser/#/R-GGA-74258 XDH oxidizes xanthine to form urate IEA Gallus gallus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-GGA-76031 https://reactome.org/PathwayBrowser/#/R-GGA-76031 2 H2O2 => O2 + 2 H2O IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76354 https://reactome.org/PathwayBrowser/#/R-GGA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76373 https://reactome.org/PathwayBrowser/#/R-GGA-76373 N-hydroxylation of 4-aminobiphenyl IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76386 https://reactome.org/PathwayBrowser/#/R-GGA-76386 CYP1A2 S-demethylates 6MMP IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76397 https://reactome.org/PathwayBrowser/#/R-GGA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76416 https://reactome.org/PathwayBrowser/#/R-GGA-76416 Benzene is hydroxylated to phenol IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76426 https://reactome.org/PathwayBrowser/#/R-GGA-76426 N-atom dealkylation of caffeine IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76456 https://reactome.org/PathwayBrowser/#/R-GGA-76456 O-atom dealkylation of dextromethorphan IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76466 https://reactome.org/PathwayBrowser/#/R-GGA-76466 CYP4A11 12-hydroxylates DDCX IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76472 https://reactome.org/PathwayBrowser/#/R-GGA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-76475 https://reactome.org/PathwayBrowser/#/R-GGA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8847579 https://reactome.org/PathwayBrowser/#/R-GGA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8865107 https://reactome.org/PathwayBrowser/#/R-GGA-8865107 MICAL1 produces NADP+, H2O2 IEA Gallus gallus 15379 R-ALL-5668566 O2 [melanosome lumen] R-GGA-8878581 https://reactome.org/PathwayBrowser/#/R-GGA-8878581 TYRP1 oxidises DHICA to IQCA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-888614 https://reactome.org/PathwayBrowser/#/R-GGA-888614 IDO2 dioxygenates L-Trp to NFK IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-8956458 https://reactome.org/PathwayBrowser/#/R-GGA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8981606 https://reactome.org/PathwayBrowser/#/R-GGA-8981606 Myoglobin binds oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8981610 https://reactome.org/PathwayBrowser/#/R-GGA-8981610 Neuroglobin binds oxygen IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8981621 https://reactome.org/PathwayBrowser/#/R-GGA-8981621 Neuroglobin:oxygen dissociates IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8981622 https://reactome.org/PathwayBrowser/#/R-GGA-8981622 Myoglobin:oxygen dissociates IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-8982617 https://reactome.org/PathwayBrowser/#/R-GGA-8982617 CYGB:O2 dissociates IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9018858 https://reactome.org/PathwayBrowser/#/R-GGA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9018859 https://reactome.org/PathwayBrowser/#/R-GGA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9018863 https://reactome.org/PathwayBrowser/#/R-GGA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9018880 https://reactome.org/PathwayBrowser/#/R-GGA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9018894 https://reactome.org/PathwayBrowser/#/R-GGA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9020251 https://reactome.org/PathwayBrowser/#/R-GGA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9020259 https://reactome.org/PathwayBrowser/#/R-GGA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9020261 https://reactome.org/PathwayBrowser/#/R-GGA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9020264 https://reactome.org/PathwayBrowser/#/R-GGA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9020282 https://reactome.org/PathwayBrowser/#/R-GGA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9024997 https://reactome.org/PathwayBrowser/#/R-GGA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9025996 https://reactome.org/PathwayBrowser/#/R-GGA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9026005 https://reactome.org/PathwayBrowser/#/R-GGA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9026405 https://reactome.org/PathwayBrowser/#/R-GGA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9026408 https://reactome.org/PathwayBrowser/#/R-GGA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027043 https://reactome.org/PathwayBrowser/#/R-GGA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027302 https://reactome.org/PathwayBrowser/#/R-GGA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027321 https://reactome.org/PathwayBrowser/#/R-GGA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027532 https://reactome.org/PathwayBrowser/#/R-GGA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027607 https://reactome.org/PathwayBrowser/#/R-GGA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027624 https://reactome.org/PathwayBrowser/#/R-GGA-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027627 https://reactome.org/PathwayBrowser/#/R-GGA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027628 https://reactome.org/PathwayBrowser/#/R-GGA-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9027633 https://reactome.org/PathwayBrowser/#/R-GGA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9028255 https://reactome.org/PathwayBrowser/#/R-GGA-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9037761 https://reactome.org/PathwayBrowser/#/R-GGA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-917891 https://reactome.org/PathwayBrowser/#/R-GGA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-917933 https://reactome.org/PathwayBrowser/#/R-GGA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9629578 https://reactome.org/PathwayBrowser/#/R-GGA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9629591 https://reactome.org/PathwayBrowser/#/R-GGA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9629869 https://reactome.org/PathwayBrowser/#/R-GGA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9629946 https://reactome.org/PathwayBrowser/#/R-GGA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-9630022 https://reactome.org/PathwayBrowser/#/R-GGA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-9630769 https://reactome.org/PathwayBrowser/#/R-GGA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-9630967 https://reactome.org/PathwayBrowser/#/R-GGA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-GGA-9630993 https://reactome.org/PathwayBrowser/#/R-GGA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-965019 https://reactome.org/PathwayBrowser/#/R-GGA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-965079 https://reactome.org/PathwayBrowser/#/R-GGA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Gallus gallus 15379 R-ALL-352327 O2 [extracellular region] R-GGA-9709360 https://reactome.org/PathwayBrowser/#/R-GGA-9709360 H2O2 reduces MetHb IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-9749986 https://reactome.org/PathwayBrowser/#/R-GGA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-9750016 https://reactome.org/PathwayBrowser/#/R-GGA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9753285 https://reactome.org/PathwayBrowser/#/R-GGA-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9756138 https://reactome.org/PathwayBrowser/#/R-GGA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9756162 https://reactome.org/PathwayBrowser/#/R-GGA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9756169 https://reactome.org/PathwayBrowser/#/R-GGA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9756180 https://reactome.org/PathwayBrowser/#/R-GGA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-975635 https://reactome.org/PathwayBrowser/#/R-GGA-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9758674 https://reactome.org/PathwayBrowser/#/R-GGA-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-9817575 https://reactome.org/PathwayBrowser/#/R-GGA-9817575 ERO1B oxidizes P4HB IEA Gallus gallus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-GGA-9856718 https://reactome.org/PathwayBrowser/#/R-GGA-9856718 HPDL dioxygenates HPPA IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9915971 https://reactome.org/PathwayBrowser/#/R-GGA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-9915992 https://reactome.org/PathwayBrowser/#/R-GGA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Gallus gallus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-GGA-9915993 https://reactome.org/PathwayBrowser/#/R-GGA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Gallus gallus 15379 R-ALL-29368 O2 [cytosol] R-GGA-9915997 https://reactome.org/PathwayBrowser/#/R-GGA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Gallus gallus 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112118 https://reactome.org/PathwayBrowser/#/R-HSA-112118 Oxidative demethylation of 1-meA damaged DNA by ALKBH2 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112120 https://reactome.org/PathwayBrowser/#/R-HSA-112120 Oxidative demethylation of 3-meC damaged DNA by ALKBH2 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112121 https://reactome.org/PathwayBrowser/#/R-HSA-112121 Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112123 https://reactome.org/PathwayBrowser/#/R-HSA-112123 Oxidative demethylation of 1-meA damaged DNA By ALKBH3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112124 https://reactome.org/PathwayBrowser/#/R-HSA-112124 Oxidative demethylation of 3-meC damaged DNA By ALKBH3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-112125 https://reactome.org/PathwayBrowser/#/R-HSA-112125 Oxidative dealkylation of 1-EtA damaged DNA by ABH3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1222376 https://reactome.org/PathwayBrowser/#/R-HSA-1222376 NOX2 generates superoxide from oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1222462 https://reactome.org/PathwayBrowser/#/R-HSA-1222462 SodB reduces superoxide to H2O2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1222469 https://reactome.org/PathwayBrowser/#/R-HSA-1222469 SodC reduces superoxide to H2O2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1222704 https://reactome.org/PathwayBrowser/#/R-HSA-1222704 KatG reduces H2O2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1222723 https://reactome.org/PathwayBrowser/#/R-HSA-1222723 Nitric oxide is oxidized to nitrate TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1234164 https://reactome.org/PathwayBrowser/#/R-HSA-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-1234165 https://reactome.org/PathwayBrowser/#/R-HSA-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-1234166 https://reactome.org/PathwayBrowser/#/R-HSA-1234166 Nuclear PHD1,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1234173 https://reactome.org/PathwayBrowser/#/R-HSA-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1234177 https://reactome.org/PathwayBrowser/#/R-HSA-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1234179 https://reactome.org/PathwayBrowser/#/R-HSA-1234179 Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-1234181 https://reactome.org/PathwayBrowser/#/R-HSA-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A TAS Homo sapiens 15379 R-ALL-1236709 O2 [phagolysosome] R-HSA-1236967 https://reactome.org/PathwayBrowser/#/R-HSA-1236967 Alkalization of the phagosomal lumen by NOX2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1237119 https://reactome.org/PathwayBrowser/#/R-HSA-1237119 Acireductone is oxidized to MOB TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1237325 https://reactome.org/PathwayBrowser/#/R-HSA-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1247668 https://reactome.org/PathwayBrowser/#/R-HSA-1247668 Hemoglobin A binds O2, releasing H+ and CO2 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-139970 https://reactome.org/PathwayBrowser/#/R-HSA-139970 FMO3:FAD N-oxidises TMA to TMAO TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-140355 https://reactome.org/PathwayBrowser/#/R-HSA-140355 Arachidonate is oxidised to PGG2 by PTGS1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-141186 https://reactome.org/PathwayBrowser/#/R-HSA-141186 MAOA:FAD oxidatively deaminates of 5HT TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-141200 https://reactome.org/PathwayBrowser/#/R-HSA-141200 MAOB:FAD oxidatively deaminates of PEA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-141202 https://reactome.org/PathwayBrowser/#/R-HSA-141202 MAOB:FAD oxidatively deaminates TYR TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-141341 https://reactome.org/PathwayBrowser/#/R-HSA-141341 SMOX-3 oxidises SPN to SPM TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-141348 https://reactome.org/PathwayBrowser/#/R-HSA-141348 PAO:FAD oxidises NASPM to PTCN TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-141351 https://reactome.org/PathwayBrowser/#/R-HSA-141351 PAOX:FAD oxidises NASPN to SPM TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-143468 https://reactome.org/PathwayBrowser/#/R-HSA-143468 MEOS oxidizes ethanol to acetaldehyde TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1497810 https://reactome.org/PathwayBrowser/#/R-HSA-1497810 Uncoupled eNOS favours the formation of superoxide TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1562603 https://reactome.org/PathwayBrowser/#/R-HSA-1562603 BfrB stores iron TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1562604 https://reactome.org/PathwayBrowser/#/R-HSA-1562604 BfrA stores iron TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1562626 https://reactome.org/PathwayBrowser/#/R-HSA-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-156526 https://reactome.org/PathwayBrowser/#/R-HSA-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159752 https://reactome.org/PathwayBrowser/#/R-HSA-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159761 https://reactome.org/PathwayBrowser/#/R-HSA-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159795 https://reactome.org/PathwayBrowser/#/R-HSA-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159803 https://reactome.org/PathwayBrowser/#/R-HSA-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159819 https://reactome.org/PathwayBrowser/#/R-HSA-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-159826 https://reactome.org/PathwayBrowser/#/R-HSA-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-1614544 https://reactome.org/PathwayBrowser/#/R-HSA-1614544 Sulfite is oxidized to sulfate TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-1614605 https://reactome.org/PathwayBrowser/#/R-HSA-1614605 Persulfide sulfur is dioxygenated TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1614645 https://reactome.org/PathwayBrowser/#/R-HSA-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-163214 https://reactome.org/PathwayBrowser/#/R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-163810 https://reactome.org/PathwayBrowser/#/R-HSA-163810 GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) IEA Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-163820 https://reactome.org/PathwayBrowser/#/R-HSA-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-1650808 https://reactome.org/PathwayBrowser/#/R-HSA-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-1655453 https://reactome.org/PathwayBrowser/#/R-HSA-1655453 FMO1:FAD oxidizes HTAU to TAU TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-189398 https://reactome.org/PathwayBrowser/#/R-HSA-189398 HMOX1 dimer, HMOX2 cleave heme TAS Homo sapiens 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-HSA-189421 https://reactome.org/PathwayBrowser/#/R-HSA-189421 CPO transforms COPRO3 to PPGEN9 TAS Homo sapiens 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-HSA-189423 https://reactome.org/PathwayBrowser/#/R-HSA-189423 PPO oxidises PPGEN9 to PRIN9 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-191299 https://reactome.org/PathwayBrowser/#/R-HSA-191299 Squalene is oxidized to its epoxide TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-191972 https://reactome.org/PathwayBrowser/#/R-HSA-191972 27-hydroxycholesterol is 7alpha-hydroxylated TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-191983 https://reactome.org/PathwayBrowser/#/R-HSA-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-191999 https://reactome.org/PathwayBrowser/#/R-HSA-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-192051 https://reactome.org/PathwayBrowser/#/R-HSA-192051 CYP7A1 7-hydroxylates CHOL TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-192054 https://reactome.org/PathwayBrowser/#/R-HSA-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-192061 https://reactome.org/PathwayBrowser/#/R-HSA-192061 CYP46A1 24-hydroxylates CHOL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-192065 https://reactome.org/PathwayBrowser/#/R-HSA-192065 CYP7B1 7-hydroxylates 25OH-CHOL TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-192123 https://reactome.org/PathwayBrowser/#/R-HSA-192123 CYP27A1 27-hydroxylates CHOL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-192157 https://reactome.org/PathwayBrowser/#/R-HSA-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-192178 https://reactome.org/PathwayBrowser/#/R-HSA-192178 CYP39A1 7-hydroxylates 24OH-CHOL TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-192335 https://reactome.org/PathwayBrowser/#/R-HSA-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193054 https://reactome.org/PathwayBrowser/#/R-HSA-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193060 https://reactome.org/PathwayBrowser/#/R-HSA-193060 CYP19A1 hydroxylates ANDST to E1 TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193065 https://reactome.org/PathwayBrowser/#/R-HSA-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193068 https://reactome.org/PathwayBrowser/#/R-HSA-193068 CYP17A1 17-hydroxylates PREG TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193070 https://reactome.org/PathwayBrowser/#/R-HSA-193070 CYP17A1 cleaves 17aHPREG to DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193072 https://reactome.org/PathwayBrowser/#/R-HSA-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193099 https://reactome.org/PathwayBrowser/#/R-HSA-193099 CYP17A1 cleaves 17aHPROG to ANDST TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193101 https://reactome.org/PathwayBrowser/#/R-HSA-193101 CYP11A1 cleaves 20a,22b-DHCHOL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193143 https://reactome.org/PathwayBrowser/#/R-HSA-193143 CYP19A1 hydroxylates TEST to EST17b TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-193369 https://reactome.org/PathwayBrowser/#/R-HSA-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193393 https://reactome.org/PathwayBrowser/#/R-HSA-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193460 https://reactome.org/PathwayBrowser/#/R-HSA-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193709 https://reactome.org/PathwayBrowser/#/R-HSA-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193713 https://reactome.org/PathwayBrowser/#/R-HSA-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193719 https://reactome.org/PathwayBrowser/#/R-HSA-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193737 https://reactome.org/PathwayBrowser/#/R-HSA-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193780 https://reactome.org/PathwayBrowser/#/R-HSA-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193787 https://reactome.org/PathwayBrowser/#/R-HSA-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193792 https://reactome.org/PathwayBrowser/#/R-HSA-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193845 https://reactome.org/PathwayBrowser/#/R-HSA-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193964 https://reactome.org/PathwayBrowser/#/R-HSA-193964 CYP21A2 21-hydroxylates PROG TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193965 https://reactome.org/PathwayBrowser/#/R-HSA-193965 CYP11B2 oxidises 18HCORST to ALDO TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-193981 https://reactome.org/PathwayBrowser/#/R-HSA-193981 CYP21A2 oxidises 17HPROG TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193995 https://reactome.org/PathwayBrowser/#/R-HSA-193995 CYP11B2 18-hydroxylates CORST to 18HCORST TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-193997 https://reactome.org/PathwayBrowser/#/R-HSA-193997 CYP11B1 oxidises 11DCORT TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-194017 https://reactome.org/PathwayBrowser/#/R-HSA-194017 CYP11B2 oxidises 11DCORST to CORST TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-194641 https://reactome.org/PathwayBrowser/#/R-HSA-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-194669 https://reactome.org/PathwayBrowser/#/R-HSA-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-194678 https://reactome.org/PathwayBrowser/#/R-HSA-194678 CYP51A1 demethylates LNSOL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-195664 https://reactome.org/PathwayBrowser/#/R-HSA-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-1980233 https://reactome.org/PathwayBrowser/#/R-HSA-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-1981104 https://reactome.org/PathwayBrowser/#/R-HSA-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-198563 https://reactome.org/PathwayBrowser/#/R-HSA-198563 IDO1 dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2002466 https://reactome.org/PathwayBrowser/#/R-HSA-2002466 Formation of allysine by LOX TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-202127 https://reactome.org/PathwayBrowser/#/R-HSA-202127 eNOS synthesizes NO TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046084 https://reactome.org/PathwayBrowser/#/R-HSA-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046089 https://reactome.org/PathwayBrowser/#/R-HSA-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046092 https://reactome.org/PathwayBrowser/#/R-HSA-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046096 https://reactome.org/PathwayBrowser/#/R-HSA-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046097 https://reactome.org/PathwayBrowser/#/R-HSA-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2046099 https://reactome.org/PathwayBrowser/#/R-HSA-2046099 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA IEA Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-204662 https://reactome.org/PathwayBrowser/#/R-HSA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-2066787 https://reactome.org/PathwayBrowser/#/R-HSA-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-209765 https://reactome.org/PathwayBrowser/#/R-HSA-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-209823 https://reactome.org/PathwayBrowser/#/R-HSA-209823 Tyrosine is hydroxylated to dopa TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-209828 https://reactome.org/PathwayBrowser/#/R-HSA-209828 Tryptophan is hydroxylated TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-209845 https://reactome.org/PathwayBrowser/#/R-HSA-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-209868 https://reactome.org/PathwayBrowser/#/R-HSA-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D TAS Homo sapiens 15379 R-ALL-351593 O2 [secretory granule lumen] R-HSA-209891 https://reactome.org/PathwayBrowser/#/R-HSA-209891 Dopamine is oxidised to noradrenaline TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-211873 https://reactome.org/PathwayBrowser/#/R-HSA-211873 CYP4F2, 4F3 20-hydroxylate LTB4 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211874 https://reactome.org/PathwayBrowser/#/R-HSA-211874 CYP2S1 4-hydroxylates atRA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211881 https://reactome.org/PathwayBrowser/#/R-HSA-211881 Coumarin is 7-hydroxylated by CYP2A13 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211882 https://reactome.org/PathwayBrowser/#/R-HSA-211882 CYP3A7 can 6beta-hydroxylate testosterone TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211904 https://reactome.org/PathwayBrowser/#/R-HSA-211904 CYP4F12 18-hydroxylates ARA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211910 https://reactome.org/PathwayBrowser/#/R-HSA-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211919 https://reactome.org/PathwayBrowser/#/R-HSA-211919 CYP4F8 19-hydroxylates PGH2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-211923 https://reactome.org/PathwayBrowser/#/R-HSA-211923 CYP26C1 4-hydroxylates 9cRA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211924 https://reactome.org/PathwayBrowser/#/R-HSA-211924 CYP4B1 12-hydroxylates ARA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211929 https://reactome.org/PathwayBrowser/#/R-HSA-211929 CYP2C19 5-hydroxylates omeprazole TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211948 https://reactome.org/PathwayBrowser/#/R-HSA-211948 CYP3A4 can N-demethylate loperamide TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-211950 https://reactome.org/PathwayBrowser/#/R-HSA-211950 CYP24A1 24-hydroxylates CTL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-211951 https://reactome.org/PathwayBrowser/#/R-HSA-211951 CYP1B1 4-hydroxylates EST17b TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211959 https://reactome.org/PathwayBrowser/#/R-HSA-211959 CYP3A43 6b-hydroxylates TEST TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211960 https://reactome.org/PathwayBrowser/#/R-HSA-211960 CYP2U1 19-hydroxylates ARA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211962 https://reactome.org/PathwayBrowser/#/R-HSA-211962 CYP4F11 16-hydroxylates 3OH-PALM TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211966 https://reactome.org/PathwayBrowser/#/R-HSA-211966 CYP2D6 4-hydroxylates debrisoquine TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211968 https://reactome.org/PathwayBrowser/#/R-HSA-211968 CYP2W1 oxidises INDOL TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211983 https://reactome.org/PathwayBrowser/#/R-HSA-211983 CYP2J2 oxidises ARA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211988 https://reactome.org/PathwayBrowser/#/R-HSA-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-211991 https://reactome.org/PathwayBrowser/#/R-HSA-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-212004 https://reactome.org/PathwayBrowser/#/R-HSA-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-212005 https://reactome.org/PathwayBrowser/#/R-HSA-212005 CYP2F1 dehydrogenates 3-methylindole TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-212007 https://reactome.org/PathwayBrowser/#/R-HSA-212007 CYP26A1,B1 4-hydroxylate atRA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-213175 https://reactome.org/PathwayBrowser/#/R-HSA-213175 CYP3A4,5 oxidise AFB1 to AFXBO TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-215526 https://reactome.org/PathwayBrowser/#/R-HSA-215526 CYP4F3 20-hydroxylates LTB4 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2160492 https://reactome.org/PathwayBrowser/#/R-HSA-2160492 IL4I1:FAD oxidises L-Phe to kPPV TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161745 https://reactome.org/PathwayBrowser/#/R-HSA-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161775 https://reactome.org/PathwayBrowser/#/R-HSA-2161775 ALOX12 oxidises LTA4 to LXA4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161792 https://reactome.org/PathwayBrowser/#/R-HSA-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161794 https://reactome.org/PathwayBrowser/#/R-HSA-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2161795 https://reactome.org/PathwayBrowser/#/R-HSA-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2161814 https://reactome.org/PathwayBrowser/#/R-HSA-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161890 https://reactome.org/PathwayBrowser/#/R-HSA-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161899 https://reactome.org/PathwayBrowser/#/R-HSA-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161907 https://reactome.org/PathwayBrowser/#/R-HSA-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161917 https://reactome.org/PathwayBrowser/#/R-HSA-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2161940 https://reactome.org/PathwayBrowser/#/R-HSA-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161950 https://reactome.org/PathwayBrowser/#/R-HSA-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161951 https://reactome.org/PathwayBrowser/#/R-HSA-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161964 https://reactome.org/PathwayBrowser/#/R-HSA-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2161979 https://reactome.org/PathwayBrowser/#/R-HSA-2161979 20cho-LTB4 is oxidised to 20cooh-LTB4 by ALDH TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-2162002 https://reactome.org/PathwayBrowser/#/R-HSA-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-2162187 https://reactome.org/PathwayBrowser/#/R-HSA-2162187 COQ6 hydroxylates DHB TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-2162191 https://reactome.org/PathwayBrowser/#/R-HSA-2162191 Unknown enzyme hydroxylates DMPhOH IEA Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-2162194 https://reactome.org/PathwayBrowser/#/R-HSA-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2168883 https://reactome.org/PathwayBrowser/#/R-HSA-2168883 Haptoglobin:Hemoglobin binds CD163 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2168885 https://reactome.org/PathwayBrowser/#/R-HSA-2168885 Haptoglobin binds Hemoglobin TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2168889 https://reactome.org/PathwayBrowser/#/R-HSA-2168889 Haptoglobin-related Protein binds Hemoglobin TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-217255 https://reactome.org/PathwayBrowser/#/R-HSA-217255 FMO1:FAD N-oxidises TAM TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-217258 https://reactome.org/PathwayBrowser/#/R-HSA-217258 FMO2:FAD:Mg2+ S-oxidises MTZ TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-2172678 https://reactome.org/PathwayBrowser/#/R-HSA-2172678 PHF8 demethylates histone H4K20me1 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2230938 https://reactome.org/PathwayBrowser/#/R-HSA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed TAS Homo sapiens 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-HSA-2230938 https://reactome.org/PathwayBrowser/#/R-HSA-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-2309787 https://reactome.org/PathwayBrowser/#/R-HSA-2309787 Arachidonate is oxidised to PGG2 by PTGS2 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-2395340 https://reactome.org/PathwayBrowser/#/R-HSA-2395340 Formation of hydroxyallysine by LOX TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-265296 https://reactome.org/PathwayBrowser/#/R-HSA-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-3204311 https://reactome.org/PathwayBrowser/#/R-HSA-3204311 AOX1 oxidises PXL to PDXate TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-3299680 https://reactome.org/PathwayBrowser/#/R-HSA-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-3299682 https://reactome.org/PathwayBrowser/#/R-HSA-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-3299691 https://reactome.org/PathwayBrowser/#/R-HSA-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) TAS Homo sapiens 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-HSA-3341294 https://reactome.org/PathwayBrowser/#/R-HSA-3341294 Superoxide reduces cytochrome c TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-374909 https://reactome.org/PathwayBrowser/#/R-HSA-374909 Catabolism of Noradrenaline TAS Homo sapiens 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-HSA-3777112 https://reactome.org/PathwayBrowser/#/R-HSA-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-379382 https://reactome.org/PathwayBrowser/#/R-HSA-379382 MAOA:FAD deaminates DA to DOPAC TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-379395 https://reactome.org/PathwayBrowser/#/R-HSA-379395 MAOA:FAD deaminates 3MT to HVA TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389639 https://reactome.org/PathwayBrowser/#/R-HSA-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389821 https://reactome.org/PathwayBrowser/#/R-HSA-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389842 https://reactome.org/PathwayBrowser/#/R-HSA-389842 HAO1 tetramer oxidizes glycolate to glyoxylate TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389862 https://reactome.org/PathwayBrowser/#/R-HSA-389862 Conversion of glyoxylate to oxalate TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389889 https://reactome.org/PathwayBrowser/#/R-HSA-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-389891 https://reactome.org/PathwayBrowser/#/R-HSA-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-390256 https://reactome.org/PathwayBrowser/#/R-HSA-390256 ACOX1 oxidizes C26:0 CoA TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-390302 https://reactome.org/PathwayBrowser/#/R-HSA-390302 Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-418436 https://reactome.org/PathwayBrowser/#/R-HSA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-428259 https://reactome.org/PathwayBrowser/#/R-HSA-428259 DEGS1 dehydrogenates dihydroceramide TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-428260 https://reactome.org/PathwayBrowser/#/R-HSA-428260 DEGS2 oxygenates dihydroceramide TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4722133 https://reactome.org/PathwayBrowser/#/R-HSA-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4724279 https://reactome.org/PathwayBrowser/#/R-HSA-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4724284 https://reactome.org/PathwayBrowser/#/R-HSA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4754176 https://reactome.org/PathwayBrowser/#/R-HSA-4754176 JMJD6 demethylates MeR3-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4754181 https://reactome.org/PathwayBrowser/#/R-HSA-4754181 KDM5A-D demethylate Me2K5-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-4754187 https://reactome.org/PathwayBrowser/#/R-HSA-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5164399 https://reactome.org/PathwayBrowser/#/R-HSA-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5218841 https://reactome.org/PathwayBrowser/#/R-HSA-5218841 NADPH oxidase 2 generates superoxide from oxygen TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5220952 https://reactome.org/PathwayBrowser/#/R-HSA-5220952 TET1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5220990 https://reactome.org/PathwayBrowser/#/R-HSA-5220990 TET1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5221014 https://reactome.org/PathwayBrowser/#/R-HSA-5221014 TET1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine IEA Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5340214 https://reactome.org/PathwayBrowser/#/R-HSA-5340214 CYGB binds O2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5340226 https://reactome.org/PathwayBrowser/#/R-HSA-5340226 CYGB dioxygenates NO TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5362525 https://reactome.org/PathwayBrowser/#/R-HSA-5362525 CYP26A1,B1,C1 4-hydroxylate atRA TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5423117 https://reactome.org/PathwayBrowser/#/R-HSA-5423117 PHF8 demethylates MeK21-histone H4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5423647 https://reactome.org/PathwayBrowser/#/R-HSA-5423647 CYP2A13 oxidises AFM1 to AFM1E TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5423664 https://reactome.org/PathwayBrowser/#/R-HSA-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5423672 https://reactome.org/PathwayBrowser/#/R-HSA-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5423678 https://reactome.org/PathwayBrowser/#/R-HSA-5423678 CYP1A2 hydroxylates AFB1 to AFM1 TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5580269 https://reactome.org/PathwayBrowser/#/R-HSA-5580269 Defective CYP11A1 does not cleave 20a,22b-DHCHOL TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5580292 https://reactome.org/PathwayBrowser/#/R-HSA-5580292 Defective CYP11B1 does not oxidise 11DCORT TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5600598 https://reactome.org/PathwayBrowser/#/R-HSA-5600598 Defective CYP11B2 does not oxidise 11DCORST TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5601843 https://reactome.org/PathwayBrowser/#/R-HSA-5601843 Defective CYP17A1 does not 17-hydroxylate PREG TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5601849 https://reactome.org/PathwayBrowser/#/R-HSA-5601849 Defective CYP19A1 does not convert ANDST to E1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5601976 https://reactome.org/PathwayBrowser/#/R-HSA-5601976 Defective CYP21A2 does not 21-hydroxylate PROG TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5602004 https://reactome.org/PathwayBrowser/#/R-HSA-5602004 Defective CYP24A1 does not 24-hydroxylate CALTOL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602050 https://reactome.org/PathwayBrowser/#/R-HSA-5602050 Defective CYP26C1 does not 4-hydroxylate 9cRA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-5602063 https://reactome.org/PathwayBrowser/#/R-HSA-5602063 Defective CYP26B1 does not 4-hydroxylate atRA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602147 https://reactome.org/PathwayBrowser/#/R-HSA-5602147 Defective CYP2R1 does not 25-hydroxylate vitamin D TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5602170 https://reactome.org/PathwayBrowser/#/R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602186 https://reactome.org/PathwayBrowser/#/R-HSA-5602186 Defective CYP27B1 does not hydroxylate CDL TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-5602242 https://reactome.org/PathwayBrowser/#/R-HSA-5602242 Defective CYP2U1 does not omega-hydroxylate ARA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602272 https://reactome.org/PathwayBrowser/#/R-HSA-5602272 Defective CYP4F22 does not 20-hydroxylate TrXA3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602295 https://reactome.org/PathwayBrowser/#/R-HSA-5602295 CYP4F22 20-hydroxylates TrXA3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5602885 https://reactome.org/PathwayBrowser/#/R-HSA-5602885 Defective CYP7B1 does not 7-hydroxylate 25OH-CHOL TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-5602966 https://reactome.org/PathwayBrowser/#/R-HSA-5602966 Defective FMO3 does not N-oxidise TMA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5603108 https://reactome.org/PathwayBrowser/#/R-HSA-5603108 Defective MAOA does not oxidatively deaminate 5HT TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5605147 https://reactome.org/PathwayBrowser/#/R-HSA-5605147 Defective CYP1B1 does not 4-hydroxylate EST17b TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5621402 https://reactome.org/PathwayBrowser/#/R-HSA-5621402 Defective CP does not oxidise Fe2+ to Fe3+ TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5625797 https://reactome.org/PathwayBrowser/#/R-HSA-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5625848 https://reactome.org/PathwayBrowser/#/R-HSA-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5625870 https://reactome.org/PathwayBrowser/#/R-HSA-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5649483 https://reactome.org/PathwayBrowser/#/R-HSA-5649483 Defective PAH does not hydroxylate L-Phe to L-Tyr TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661114 https://reactome.org/PathwayBrowser/#/R-HSA-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661115 https://reactome.org/PathwayBrowser/#/R-HSA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661116 https://reactome.org/PathwayBrowser/#/R-HSA-5661116 KDM5A-D demethylate Me3K5-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661120 https://reactome.org/PathwayBrowser/#/R-HSA-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661121 https://reactome.org/PathwayBrowser/#/R-HSA-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661122 https://reactome.org/PathwayBrowser/#/R-HSA-5661122 JMJD6 demethylates Me2R3-histone H3 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661124 https://reactome.org/PathwayBrowser/#/R-HSA-5661124 JMJD6 demethylates MeR4-HIST1H4 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-5661125 https://reactome.org/PathwayBrowser/#/R-HSA-5661125 JMJD6 demethylates Me2sR4-HIST1H4 TAS Homo sapiens 15379 R-ALL-5668566 O2 [melanosome lumen] R-HSA-5662692 https://reactome.org/PathwayBrowser/#/R-HSA-5662692 Dopa is oxidized to dopaquinone by TYR TAS Homo sapiens 15379 R-ALL-1236709 O2 [phagolysosome] R-HSA-5668629 https://reactome.org/PathwayBrowser/#/R-HSA-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5668718 https://reactome.org/PathwayBrowser/#/R-HSA-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5668731 https://reactome.org/PathwayBrowser/#/R-HSA-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5678327 https://reactome.org/PathwayBrowser/#/R-HSA-5678327 MIOX oxidises Ins to GlcA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5690565 https://reactome.org/PathwayBrowser/#/R-HSA-5690565 SCD desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-5691107 https://reactome.org/PathwayBrowser/#/R-HSA-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5693681 https://reactome.org/PathwayBrowser/#/R-HSA-5693681 DUOX1,2 reduce O2 to H2O2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5693761 https://reactome.org/PathwayBrowser/#/R-HSA-5693761 FA2H hydroxylates 1,2-saturated fatty acids TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-5696119 https://reactome.org/PathwayBrowser/#/R-HSA-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5696131 https://reactome.org/PathwayBrowser/#/R-HSA-5696131 AOC1 deaminates Hist TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5696146 https://reactome.org/PathwayBrowser/#/R-HSA-5696146 AOC2 deaminates TYR TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-5696183 https://reactome.org/PathwayBrowser/#/R-HSA-5696183 AOC3 deaminates BZAM TAS Homo sapiens 15379 R-ALL-1131511 O2 [cytoplasm] R-HSA-6783455 https://reactome.org/PathwayBrowser/#/R-HSA-6783455 TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-6783880 https://reactome.org/PathwayBrowser/#/R-HSA-6783880 PIPOX oxidises PPCA to P6C TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-6785244 https://reactome.org/PathwayBrowser/#/R-HSA-6785244 Defective CYP11B2 does not oxidise 18HCORST TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-6785245 https://reactome.org/PathwayBrowser/#/R-HSA-6785245 Defective CYP11B2 does not oxidise CORST TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6786239 https://reactome.org/PathwayBrowser/#/R-HSA-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-6787811 https://reactome.org/PathwayBrowser/#/R-HSA-6787811 HAO2 tetramer oxidises 2OH-PALM TAS Homo sapiens 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-HSA-6789092 https://reactome.org/PathwayBrowser/#/R-HSA-6789092 NOX2 generates superoxide anion from oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6799733 https://reactome.org/PathwayBrowser/#/R-HSA-6799733 Semiquinone reacts with oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6803989 https://reactome.org/PathwayBrowser/#/R-HSA-6803989 Nitric oxide and O2 react to NO2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6807053 https://reactome.org/PathwayBrowser/#/R-HSA-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-6807214 https://reactome.org/PathwayBrowser/#/R-HSA-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6807557 https://reactome.org/PathwayBrowser/#/R-HSA-6807557 NOX4, NOX5 reduce O2 to O2.- TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-6810076 https://reactome.org/PathwayBrowser/#/R-HSA-6810076 DDO oxidizes D-Asp to OA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-6814153 https://reactome.org/PathwayBrowser/#/R-HSA-6814153 ADO oxidises 2AET to HTAU TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71118 https://reactome.org/PathwayBrowser/#/R-HSA-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71163 https://reactome.org/PathwayBrowser/#/R-HSA-71163 HPD dioxygenates HPP TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71164 https://reactome.org/PathwayBrowser/#/R-HSA-71164 HGD dioxygenates homogentisate TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71188 https://reactome.org/PathwayBrowser/#/R-HSA-71188 TDO tetramer dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71200 https://reactome.org/PathwayBrowser/#/R-HSA-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71218 https://reactome.org/PathwayBrowser/#/R-HSA-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-71241 https://reactome.org/PathwayBrowser/#/R-HSA-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-71261 https://reactome.org/PathwayBrowser/#/R-HSA-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-74247 https://reactome.org/PathwayBrowser/#/R-HSA-74247 XDH oxidizes hypoxanthine to form xanthine TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-74258 https://reactome.org/PathwayBrowser/#/R-HSA-74258 XDH oxidizes xanthine to form urate TAS Homo sapiens 15379 R-ALL-113535 O2 [peroxisomal matrix] R-HSA-76031 https://reactome.org/PathwayBrowser/#/R-HSA-76031 2 H2O2 => O2 + 2 H2O TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76354 https://reactome.org/PathwayBrowser/#/R-HSA-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76373 https://reactome.org/PathwayBrowser/#/R-HSA-76373 N-hydroxylation of 4-aminobiphenyl TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76386 https://reactome.org/PathwayBrowser/#/R-HSA-76386 CYP1A2 S-demethylates 6MMP TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76397 https://reactome.org/PathwayBrowser/#/R-HSA-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76416 https://reactome.org/PathwayBrowser/#/R-HSA-76416 Benzene is hydroxylated to phenol TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76426 https://reactome.org/PathwayBrowser/#/R-HSA-76426 N-atom dealkylation of caffeine TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76453 https://reactome.org/PathwayBrowser/#/R-HSA-76453 Coumarin is 7-hydroxylated by CYP2A6 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76456 https://reactome.org/PathwayBrowser/#/R-HSA-76456 O-atom dealkylation of dextromethorphan TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76466 https://reactome.org/PathwayBrowser/#/R-HSA-76466 CYP4A11 12-hydroxylates DDCX TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76472 https://reactome.org/PathwayBrowser/#/R-HSA-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-76475 https://reactome.org/PathwayBrowser/#/R-HSA-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8847579 https://reactome.org/PathwayBrowser/#/R-HSA-8847579 SCD5 desaturates ST-CoA to OLE-CoA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8865107 https://reactome.org/PathwayBrowser/#/R-HSA-8865107 MICAL1 produces NADP+, H2O2 TAS Homo sapiens 15379 R-ALL-5668566 O2 [melanosome lumen] R-HSA-8878581 https://reactome.org/PathwayBrowser/#/R-HSA-8878581 TYRP1 oxidises DHICA to IQCA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-888614 https://reactome.org/PathwayBrowser/#/R-HSA-888614 IDO2 dioxygenates L-Trp to NFK TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-8953398 https://reactome.org/PathwayBrowser/#/R-HSA-8953398 PIR oxygenates quercetin TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-8956458 https://reactome.org/PathwayBrowser/#/R-HSA-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8981606 https://reactome.org/PathwayBrowser/#/R-HSA-8981606 Myoglobin binds oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8981610 https://reactome.org/PathwayBrowser/#/R-HSA-8981610 Neuroglobin binds oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8981621 https://reactome.org/PathwayBrowser/#/R-HSA-8981621 Neuroglobin:oxygen dissociates TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8981622 https://reactome.org/PathwayBrowser/#/R-HSA-8981622 Myoglobin:oxygen dissociates TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-8982617 https://reactome.org/PathwayBrowser/#/R-HSA-8982617 CYGB:O2 dissociates TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018858 https://reactome.org/PathwayBrowser/#/R-HSA-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018859 https://reactome.org/PathwayBrowser/#/R-HSA-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018863 https://reactome.org/PathwayBrowser/#/R-HSA-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018874 https://reactome.org/PathwayBrowser/#/R-HSA-9018874 CYP monooxygenates EPA to 18(S)-HpEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018880 https://reactome.org/PathwayBrowser/#/R-HSA-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018894 https://reactome.org/PathwayBrowser/#/R-HSA-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9018907 https://reactome.org/PathwayBrowser/#/R-HSA-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020251 https://reactome.org/PathwayBrowser/#/R-HSA-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020259 https://reactome.org/PathwayBrowser/#/R-HSA-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020261 https://reactome.org/PathwayBrowser/#/R-HSA-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020264 https://reactome.org/PathwayBrowser/#/R-HSA-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020274 https://reactome.org/PathwayBrowser/#/R-HSA-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020275 https://reactome.org/PathwayBrowser/#/R-HSA-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020282 https://reactome.org/PathwayBrowser/#/R-HSA-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9020610 https://reactome.org/PathwayBrowser/#/R-HSA-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9024872 https://reactome.org/PathwayBrowser/#/R-HSA-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9024997 https://reactome.org/PathwayBrowser/#/R-HSA-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9025152 https://reactome.org/PathwayBrowser/#/R-HSA-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9025957 https://reactome.org/PathwayBrowser/#/R-HSA-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9025996 https://reactome.org/PathwayBrowser/#/R-HSA-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026003 https://reactome.org/PathwayBrowser/#/R-HSA-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026005 https://reactome.org/PathwayBrowser/#/R-HSA-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026006 https://reactome.org/PathwayBrowser/#/R-HSA-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026405 https://reactome.org/PathwayBrowser/#/R-HSA-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026408 https://reactome.org/PathwayBrowser/#/R-HSA-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9026918 https://reactome.org/PathwayBrowser/#/R-HSA-9026918 Lipoxygenase oxidises 17(S)-Hp-DHA to 7(S),17(S)-diHp-DHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027042 https://reactome.org/PathwayBrowser/#/R-HSA-9027042 CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027043 https://reactome.org/PathwayBrowser/#/R-HSA-9027043 CYPs hydroxylate DHA to 14(R)-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027044 https://reactome.org/PathwayBrowser/#/R-HSA-9027044 CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027302 https://reactome.org/PathwayBrowser/#/R-HSA-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027321 https://reactome.org/PathwayBrowser/#/R-HSA-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027532 https://reactome.org/PathwayBrowser/#/R-HSA-9027532 PTGS2 dimer oxidises DHA to 13-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027607 https://reactome.org/PathwayBrowser/#/R-HSA-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027624 https://reactome.org/PathwayBrowser/#/R-HSA-9027624 ALOX5 oxidises DHA to 7-HDHA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027627 https://reactome.org/PathwayBrowser/#/R-HSA-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027628 https://reactome.org/PathwayBrowser/#/R-HSA-9027628 ALOX5 oxidises EPA to 5-HEPE TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9027633 https://reactome.org/PathwayBrowser/#/R-HSA-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9028255 https://reactome.org/PathwayBrowser/#/R-HSA-9028255 PTGS2 dimer oxidises EPA to PGH3 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9035954 https://reactome.org/PathwayBrowser/#/R-HSA-9035954 Defective CYP17A1 does not 17-hydroxylate P4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9035956 https://reactome.org/PathwayBrowser/#/R-HSA-9035956 Defective CYP17A1 does not cleave 17aHPROG TAS Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-9035960 https://reactome.org/PathwayBrowser/#/R-HSA-9035960 Defective CYP27A1 does not 27-hydroxylate 5β-CHOL3α,7α,24(s)-triol TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9037761 https://reactome.org/PathwayBrowser/#/R-HSA-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-917891 https://reactome.org/PathwayBrowser/#/R-HSA-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-917933 https://reactome.org/PathwayBrowser/#/R-HSA-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9629578 https://reactome.org/PathwayBrowser/#/R-HSA-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9629591 https://reactome.org/PathwayBrowser/#/R-HSA-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9629869 https://reactome.org/PathwayBrowser/#/R-HSA-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9629888 https://reactome.org/PathwayBrowser/#/R-HSA-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9629946 https://reactome.org/PathwayBrowser/#/R-HSA-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9630022 https://reactome.org/PathwayBrowser/#/R-HSA-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9630769 https://reactome.org/PathwayBrowser/#/R-HSA-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9630967 https://reactome.org/PathwayBrowser/#/R-HSA-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9630993 https://reactome.org/PathwayBrowser/#/R-HSA-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9631355 https://reactome.org/PathwayBrowser/#/R-HSA-9631355 ASPH:Fe2+ hydroxylates an aspartate residue of F9 IEA Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-965019 https://reactome.org/PathwayBrowser/#/R-HSA-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-965079 https://reactome.org/PathwayBrowser/#/R-HSA-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9673231 https://reactome.org/PathwayBrowser/#/R-HSA-9673231 GGCX does not gamma-carboxylate 3D-F9(29-461) (pro-factor IX) TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-9673797 https://reactome.org/PathwayBrowser/#/R-HSA-9673797 NOX1 complex:pp-DVL:RAC1:GTP generates superoxide from oxygen TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9698758 https://reactome.org/PathwayBrowser/#/R-HSA-9698758 FLT3 ITD- and NOX4-dependent H2O2 production TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-9709360 https://reactome.org/PathwayBrowser/#/R-HSA-9709360 H2O2 reduces MetHb TAS Homo sapiens 15379 R-ALL-352327 O2 [extracellular region] R-HSA-9727359 https://reactome.org/PathwayBrowser/#/R-HSA-9727359 Keratinocyte of spinosum layer differentiates into keratinocyte of granulosum layer in interfollicular epidermis TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9749986 https://reactome.org/PathwayBrowser/#/R-HSA-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9750016 https://reactome.org/PathwayBrowser/#/R-HSA-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9753285 https://reactome.org/PathwayBrowser/#/R-HSA-9753285 CYP2E1 monooxygenates APAP to NAPQI TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9756138 https://reactome.org/PathwayBrowser/#/R-HSA-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9756162 https://reactome.org/PathwayBrowser/#/R-HSA-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9756169 https://reactome.org/PathwayBrowser/#/R-HSA-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9756180 https://reactome.org/PathwayBrowser/#/R-HSA-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-975635 https://reactome.org/PathwayBrowser/#/R-HSA-975635 BCMO1:Fe2+ cleaves betaC to atRAL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9758674 https://reactome.org/PathwayBrowser/#/R-HSA-9758674 CYP3A4 oxidizes PREDN,PREDL TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9794840 https://reactome.org/PathwayBrowser/#/R-HSA-9794840 Cipro is oxidized to oxo-Cipro TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9795134 https://reactome.org/PathwayBrowser/#/R-HSA-9795134 Cipro is sulfonated to sulfo-Cipro TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9817458 https://reactome.org/PathwayBrowser/#/R-HSA-9817458 TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 IEA Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9817575 https://reactome.org/PathwayBrowser/#/R-HSA-9817575 ERO1B oxidizes P4HB TAS Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9822461 https://reactome.org/PathwayBrowser/#/R-HSA-9822461 KDM5B demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9822467 https://reactome.org/PathwayBrowser/#/R-HSA-9822467 KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9822914 https://reactome.org/PathwayBrowser/#/R-HSA-9822914 KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 15379 R-ALL-113685 O2 [nucleoplasm] R-HSA-9822985 https://reactome.org/PathwayBrowser/#/R-HSA-9822985 KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) IEA Homo sapiens 15379 R-ALL-113533 O2 [mitochondrial matrix] R-HSA-9856718 https://reactome.org/PathwayBrowser/#/R-HSA-9856718 HPDL dioxygenates HPPA TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9915971 https://reactome.org/PathwayBrowser/#/R-HSA-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9915992 https://reactome.org/PathwayBrowser/#/R-HSA-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) TAS Homo sapiens 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-HSA-9915993 https://reactome.org/PathwayBrowser/#/R-HSA-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9915997 https://reactome.org/PathwayBrowser/#/R-HSA-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-HSA-9916401 https://reactome.org/PathwayBrowser/#/R-HSA-9916401 ALOX12 oxidises LTA4 to LXB4 TAS Homo sapiens 15379 R-ALL-29368 O2 [cytosol] R-MMU-1222376 https://reactome.org/PathwayBrowser/#/R-MMU-1222376 NOX2 generates superoxide from oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1234164 https://reactome.org/PathwayBrowser/#/R-MMU-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-1234165 https://reactome.org/PathwayBrowser/#/R-MMU-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1234173 https://reactome.org/PathwayBrowser/#/R-MMU-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1234177 https://reactome.org/PathwayBrowser/#/R-MMU-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-1234181 https://reactome.org/PathwayBrowser/#/R-MMU-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Mus musculus 15379 R-ALL-1236709 O2 [phagolysosome] R-MMU-1236967 https://reactome.org/PathwayBrowser/#/R-MMU-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1237119 https://reactome.org/PathwayBrowser/#/R-MMU-1237119 Acireductone is oxidized to MOB IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1237325 https://reactome.org/PathwayBrowser/#/R-MMU-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1247668 https://reactome.org/PathwayBrowser/#/R-MMU-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-139970 https://reactome.org/PathwayBrowser/#/R-MMU-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-140355 https://reactome.org/PathwayBrowser/#/R-MMU-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-141186 https://reactome.org/PathwayBrowser/#/R-MMU-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-141200 https://reactome.org/PathwayBrowser/#/R-MMU-141200 MAOB:FAD oxidatively deaminates of PEA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-141202 https://reactome.org/PathwayBrowser/#/R-MMU-141202 MAOB:FAD oxidatively deaminates TYR IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-141341 https://reactome.org/PathwayBrowser/#/R-MMU-141341 SMOX-3 oxidises SPN to SPM IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-141348 https://reactome.org/PathwayBrowser/#/R-MMU-141348 PAO:FAD oxidises NASPM to PTCN IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-141351 https://reactome.org/PathwayBrowser/#/R-MMU-141351 PAOX:FAD oxidises NASPN to SPM IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-143468 https://reactome.org/PathwayBrowser/#/R-MMU-143468 MEOS oxidizes ethanol to acetaldehyde IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1497810 https://reactome.org/PathwayBrowser/#/R-MMU-1497810 Uncoupled eNOS favours the formation of superoxide IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1562626 https://reactome.org/PathwayBrowser/#/R-MMU-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-156526 https://reactome.org/PathwayBrowser/#/R-MMU-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159752 https://reactome.org/PathwayBrowser/#/R-MMU-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159761 https://reactome.org/PathwayBrowser/#/R-MMU-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159795 https://reactome.org/PathwayBrowser/#/R-MMU-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159803 https://reactome.org/PathwayBrowser/#/R-MMU-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159819 https://reactome.org/PathwayBrowser/#/R-MMU-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-159826 https://reactome.org/PathwayBrowser/#/R-MMU-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-1614544 https://reactome.org/PathwayBrowser/#/R-MMU-1614544 Sulfite is oxidized to sulfate IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-1614605 https://reactome.org/PathwayBrowser/#/R-MMU-1614605 Persulfide sulfur is dioxygenated IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1614645 https://reactome.org/PathwayBrowser/#/R-MMU-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-163214 https://reactome.org/PathwayBrowser/#/R-MMU-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-163820 https://reactome.org/PathwayBrowser/#/R-MMU-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-1650808 https://reactome.org/PathwayBrowser/#/R-MMU-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-1655453 https://reactome.org/PathwayBrowser/#/R-MMU-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-189398 https://reactome.org/PathwayBrowser/#/R-MMU-189398 HMOX1 dimer, HMOX2 cleave heme IEA Mus musculus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-MMU-189421 https://reactome.org/PathwayBrowser/#/R-MMU-189421 CPO transforms COPRO3 to PPGEN9 IEA Mus musculus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-MMU-189423 https://reactome.org/PathwayBrowser/#/R-MMU-189423 PPO oxidises PPGEN9 to PRIN9 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-191299 https://reactome.org/PathwayBrowser/#/R-MMU-191299 Squalene is oxidized to its epoxide IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-191972 https://reactome.org/PathwayBrowser/#/R-MMU-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-191983 https://reactome.org/PathwayBrowser/#/R-MMU-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-191999 https://reactome.org/PathwayBrowser/#/R-MMU-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-192051 https://reactome.org/PathwayBrowser/#/R-MMU-192051 CYP7A1 7-hydroxylates CHOL IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-192054 https://reactome.org/PathwayBrowser/#/R-MMU-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-192061 https://reactome.org/PathwayBrowser/#/R-MMU-192061 CYP46A1 24-hydroxylates CHOL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-192065 https://reactome.org/PathwayBrowser/#/R-MMU-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-192123 https://reactome.org/PathwayBrowser/#/R-MMU-192123 CYP27A1 27-hydroxylates CHOL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-192157 https://reactome.org/PathwayBrowser/#/R-MMU-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-192178 https://reactome.org/PathwayBrowser/#/R-MMU-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-192335 https://reactome.org/PathwayBrowser/#/R-MMU-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193054 https://reactome.org/PathwayBrowser/#/R-MMU-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193060 https://reactome.org/PathwayBrowser/#/R-MMU-193060 CYP19A1 hydroxylates ANDST to E1 IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193065 https://reactome.org/PathwayBrowser/#/R-MMU-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193068 https://reactome.org/PathwayBrowser/#/R-MMU-193068 CYP17A1 17-hydroxylates PREG IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193070 https://reactome.org/PathwayBrowser/#/R-MMU-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193072 https://reactome.org/PathwayBrowser/#/R-MMU-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193099 https://reactome.org/PathwayBrowser/#/R-MMU-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193101 https://reactome.org/PathwayBrowser/#/R-MMU-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193143 https://reactome.org/PathwayBrowser/#/R-MMU-193143 CYP19A1 hydroxylates TEST to EST17b IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-193369 https://reactome.org/PathwayBrowser/#/R-MMU-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193393 https://reactome.org/PathwayBrowser/#/R-MMU-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193460 https://reactome.org/PathwayBrowser/#/R-MMU-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193709 https://reactome.org/PathwayBrowser/#/R-MMU-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193713 https://reactome.org/PathwayBrowser/#/R-MMU-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193719 https://reactome.org/PathwayBrowser/#/R-MMU-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193737 https://reactome.org/PathwayBrowser/#/R-MMU-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193780 https://reactome.org/PathwayBrowser/#/R-MMU-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193787 https://reactome.org/PathwayBrowser/#/R-MMU-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193792 https://reactome.org/PathwayBrowser/#/R-MMU-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193845 https://reactome.org/PathwayBrowser/#/R-MMU-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193964 https://reactome.org/PathwayBrowser/#/R-MMU-193964 CYP21A2 21-hydroxylates PROG IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193965 https://reactome.org/PathwayBrowser/#/R-MMU-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-193981 https://reactome.org/PathwayBrowser/#/R-MMU-193981 CYP21A2 oxidises 17HPROG IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193995 https://reactome.org/PathwayBrowser/#/R-MMU-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-193997 https://reactome.org/PathwayBrowser/#/R-MMU-193997 CYP11B1 oxidises 11DCORT IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-194017 https://reactome.org/PathwayBrowser/#/R-MMU-194017 CYP11B2 oxidises 11DCORST to CORST IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-194641 https://reactome.org/PathwayBrowser/#/R-MMU-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-194669 https://reactome.org/PathwayBrowser/#/R-MMU-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-194678 https://reactome.org/PathwayBrowser/#/R-MMU-194678 CYP51A1 demethylates LNSOL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-195664 https://reactome.org/PathwayBrowser/#/R-MMU-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-1980233 https://reactome.org/PathwayBrowser/#/R-MMU-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-1981104 https://reactome.org/PathwayBrowser/#/R-MMU-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-198563 https://reactome.org/PathwayBrowser/#/R-MMU-198563 IDO1 dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2002466 https://reactome.org/PathwayBrowser/#/R-MMU-2002466 Formation of allysine by LOX IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-202127 https://reactome.org/PathwayBrowser/#/R-MMU-202127 eNOS synthesizes NO IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2046084 https://reactome.org/PathwayBrowser/#/R-MMU-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2046089 https://reactome.org/PathwayBrowser/#/R-MMU-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2046092 https://reactome.org/PathwayBrowser/#/R-MMU-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2046096 https://reactome.org/PathwayBrowser/#/R-MMU-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2046097 https://reactome.org/PathwayBrowser/#/R-MMU-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-204662 https://reactome.org/PathwayBrowser/#/R-MMU-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-2066787 https://reactome.org/PathwayBrowser/#/R-MMU-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-209765 https://reactome.org/PathwayBrowser/#/R-MMU-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-209823 https://reactome.org/PathwayBrowser/#/R-MMU-209823 Tyrosine is hydroxylated to dopa IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-209828 https://reactome.org/PathwayBrowser/#/R-MMU-209828 Tryptophan is hydroxylated IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-209845 https://reactome.org/PathwayBrowser/#/R-MMU-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-209868 https://reactome.org/PathwayBrowser/#/R-MMU-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Mus musculus 15379 R-ALL-351593 O2 [secretory granule lumen] R-MMU-209891 https://reactome.org/PathwayBrowser/#/R-MMU-209891 Dopamine is oxidised to noradrenaline IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-211873 https://reactome.org/PathwayBrowser/#/R-MMU-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211874 https://reactome.org/PathwayBrowser/#/R-MMU-211874 CYP2S1 4-hydroxylates atRA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211881 https://reactome.org/PathwayBrowser/#/R-MMU-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211882 https://reactome.org/PathwayBrowser/#/R-MMU-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211904 https://reactome.org/PathwayBrowser/#/R-MMU-211904 CYP4F12 18-hydroxylates ARA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211910 https://reactome.org/PathwayBrowser/#/R-MMU-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211919 https://reactome.org/PathwayBrowser/#/R-MMU-211919 CYP4F8 19-hydroxylates PGH2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-211923 https://reactome.org/PathwayBrowser/#/R-MMU-211923 CYP26C1 4-hydroxylates 9cRA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211924 https://reactome.org/PathwayBrowser/#/R-MMU-211924 CYP4B1 12-hydroxylates ARA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211929 https://reactome.org/PathwayBrowser/#/R-MMU-211929 CYP2C19 5-hydroxylates omeprazole IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211948 https://reactome.org/PathwayBrowser/#/R-MMU-211948 CYP3A4 can N-demethylate loperamide IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-211950 https://reactome.org/PathwayBrowser/#/R-MMU-211950 CYP24A1 24-hydroxylates CTL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-211951 https://reactome.org/PathwayBrowser/#/R-MMU-211951 CYP1B1 4-hydroxylates EST17b IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211959 https://reactome.org/PathwayBrowser/#/R-MMU-211959 CYP3A43 6b-hydroxylates TEST IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211960 https://reactome.org/PathwayBrowser/#/R-MMU-211960 CYP2U1 19-hydroxylates ARA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211962 https://reactome.org/PathwayBrowser/#/R-MMU-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211966 https://reactome.org/PathwayBrowser/#/R-MMU-211966 CYP2D6 4-hydroxylates debrisoquine IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211968 https://reactome.org/PathwayBrowser/#/R-MMU-211968 CYP2W1 oxidises INDOL IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211983 https://reactome.org/PathwayBrowser/#/R-MMU-211983 CYP2J2 oxidises ARA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211988 https://reactome.org/PathwayBrowser/#/R-MMU-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-211991 https://reactome.org/PathwayBrowser/#/R-MMU-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-212004 https://reactome.org/PathwayBrowser/#/R-MMU-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-212005 https://reactome.org/PathwayBrowser/#/R-MMU-212005 CYP2F1 dehydrogenates 3-methylindole IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-212007 https://reactome.org/PathwayBrowser/#/R-MMU-212007 CYP26A1,B1 4-hydroxylate atRA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-213175 https://reactome.org/PathwayBrowser/#/R-MMU-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-215526 https://reactome.org/PathwayBrowser/#/R-MMU-215526 CYP4F3 20-hydroxylates LTB4 IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2160492 https://reactome.org/PathwayBrowser/#/R-MMU-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161745 https://reactome.org/PathwayBrowser/#/R-MMU-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161775 https://reactome.org/PathwayBrowser/#/R-MMU-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161792 https://reactome.org/PathwayBrowser/#/R-MMU-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161794 https://reactome.org/PathwayBrowser/#/R-MMU-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2161795 https://reactome.org/PathwayBrowser/#/R-MMU-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2161814 https://reactome.org/PathwayBrowser/#/R-MMU-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161890 https://reactome.org/PathwayBrowser/#/R-MMU-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161899 https://reactome.org/PathwayBrowser/#/R-MMU-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161907 https://reactome.org/PathwayBrowser/#/R-MMU-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161917 https://reactome.org/PathwayBrowser/#/R-MMU-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2161940 https://reactome.org/PathwayBrowser/#/R-MMU-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161950 https://reactome.org/PathwayBrowser/#/R-MMU-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161951 https://reactome.org/PathwayBrowser/#/R-MMU-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2161964 https://reactome.org/PathwayBrowser/#/R-MMU-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-2162002 https://reactome.org/PathwayBrowser/#/R-MMU-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-2162187 https://reactome.org/PathwayBrowser/#/R-MMU-2162187 COQ6 hydroxylates DHB IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-2162194 https://reactome.org/PathwayBrowser/#/R-MMU-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2168883 https://reactome.org/PathwayBrowser/#/R-MMU-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2168885 https://reactome.org/PathwayBrowser/#/R-MMU-2168885 Haptoglobin binds Hemoglobin IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2168889 https://reactome.org/PathwayBrowser/#/R-MMU-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-217255 https://reactome.org/PathwayBrowser/#/R-MMU-217255 FMO1:FAD N-oxidises TAM IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-217258 https://reactome.org/PathwayBrowser/#/R-MMU-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2230938 https://reactome.org/PathwayBrowser/#/R-MMU-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Mus musculus 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-MMU-2230938 https://reactome.org/PathwayBrowser/#/R-MMU-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-2309787 https://reactome.org/PathwayBrowser/#/R-MMU-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-2395340 https://reactome.org/PathwayBrowser/#/R-MMU-2395340 Formation of hydroxyallysine by LOX IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-265296 https://reactome.org/PathwayBrowser/#/R-MMU-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-3204311 https://reactome.org/PathwayBrowser/#/R-MMU-3204311 AOX1 oxidises PXL to PDXate IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-3299680 https://reactome.org/PathwayBrowser/#/R-MMU-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-3299682 https://reactome.org/PathwayBrowser/#/R-MMU-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-3299691 https://reactome.org/PathwayBrowser/#/R-MMU-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Mus musculus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-MMU-3341294 https://reactome.org/PathwayBrowser/#/R-MMU-3341294 Superoxide reduces cytochrome c IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-374909 https://reactome.org/PathwayBrowser/#/R-MMU-374909 Catabolism of Noradrenaline IEA Mus musculus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-MMU-3777112 https://reactome.org/PathwayBrowser/#/R-MMU-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-379382 https://reactome.org/PathwayBrowser/#/R-MMU-379382 MAOA:FAD deaminates DA to DOPAC IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-379395 https://reactome.org/PathwayBrowser/#/R-MMU-379395 MAOA:FAD deaminates 3MT to HVA IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389639 https://reactome.org/PathwayBrowser/#/R-MMU-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389821 https://reactome.org/PathwayBrowser/#/R-MMU-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389842 https://reactome.org/PathwayBrowser/#/R-MMU-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389862 https://reactome.org/PathwayBrowser/#/R-MMU-389862 Conversion of glyoxylate to oxalate IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389889 https://reactome.org/PathwayBrowser/#/R-MMU-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-389891 https://reactome.org/PathwayBrowser/#/R-MMU-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-390256 https://reactome.org/PathwayBrowser/#/R-MMU-390256 ACOX1 oxidizes C26:0 CoA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-418436 https://reactome.org/PathwayBrowser/#/R-MMU-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-428259 https://reactome.org/PathwayBrowser/#/R-MMU-428259 DEGS1 dehydrogenates dihydroceramide IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-428260 https://reactome.org/PathwayBrowser/#/R-MMU-428260 DEGS2 oxygenates dihydroceramide IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4722133 https://reactome.org/PathwayBrowser/#/R-MMU-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4724279 https://reactome.org/PathwayBrowser/#/R-MMU-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4724284 https://reactome.org/PathwayBrowser/#/R-MMU-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4754176 https://reactome.org/PathwayBrowser/#/R-MMU-4754176 JMJD6 demethylates MeR3-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4754181 https://reactome.org/PathwayBrowser/#/R-MMU-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-4754187 https://reactome.org/PathwayBrowser/#/R-MMU-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-5164399 https://reactome.org/PathwayBrowser/#/R-MMU-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5218841 https://reactome.org/PathwayBrowser/#/R-MMU-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5220931 https://reactome.org/PathwayBrowser/#/R-MMU-5220931 Tet1,2,3 oxidizes 5-hydroxymethylcytosine to 5-formylcytosine TAS Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5220936 https://reactome.org/PathwayBrowser/#/R-MMU-5220936 Tet1,2,3 oxidizes 5-formylcytosine to 5-carboxylcytosine TAS Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5220944 https://reactome.org/PathwayBrowser/#/R-MMU-5220944 Tet1,2,3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine TAS Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5340214 https://reactome.org/PathwayBrowser/#/R-MMU-5340214 CYGB binds O2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5340226 https://reactome.org/PathwayBrowser/#/R-MMU-5340226 CYGB dioxygenates NO IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5362525 https://reactome.org/PathwayBrowser/#/R-MMU-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5423117 https://reactome.org/PathwayBrowser/#/R-MMU-5423117 PHF8 demethylates MeK21-histone H4 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5423647 https://reactome.org/PathwayBrowser/#/R-MMU-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5423664 https://reactome.org/PathwayBrowser/#/R-MMU-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5423672 https://reactome.org/PathwayBrowser/#/R-MMU-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5423678 https://reactome.org/PathwayBrowser/#/R-MMU-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5602295 https://reactome.org/PathwayBrowser/#/R-MMU-5602295 CYP4F22 20-hydroxylates TrXA3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661114 https://reactome.org/PathwayBrowser/#/R-MMU-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661115 https://reactome.org/PathwayBrowser/#/R-MMU-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661116 https://reactome.org/PathwayBrowser/#/R-MMU-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661120 https://reactome.org/PathwayBrowser/#/R-MMU-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661121 https://reactome.org/PathwayBrowser/#/R-MMU-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661122 https://reactome.org/PathwayBrowser/#/R-MMU-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661124 https://reactome.org/PathwayBrowser/#/R-MMU-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-5661125 https://reactome.org/PathwayBrowser/#/R-MMU-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Mus musculus 15379 R-ALL-5668566 O2 [melanosome lumen] R-MMU-5662692 https://reactome.org/PathwayBrowser/#/R-MMU-5662692 Dopa is oxidized to dopaquinone by TYR IEA Mus musculus 15379 R-ALL-1236709 O2 [phagolysosome] R-MMU-5668629 https://reactome.org/PathwayBrowser/#/R-MMU-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5668718 https://reactome.org/PathwayBrowser/#/R-MMU-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5668731 https://reactome.org/PathwayBrowser/#/R-MMU-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5678327 https://reactome.org/PathwayBrowser/#/R-MMU-5678327 MIOX oxidises Ins to GlcA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5690565 https://reactome.org/PathwayBrowser/#/R-MMU-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-5691107 https://reactome.org/PathwayBrowser/#/R-MMU-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5693681 https://reactome.org/PathwayBrowser/#/R-MMU-5693681 DUOX1,2 reduce O2 to H2O2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5693761 https://reactome.org/PathwayBrowser/#/R-MMU-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-5696119 https://reactome.org/PathwayBrowser/#/R-MMU-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5696131 https://reactome.org/PathwayBrowser/#/R-MMU-5696131 AOC1 deaminates Hist IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5696146 https://reactome.org/PathwayBrowser/#/R-MMU-5696146 AOC2 deaminates TYR IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-5696183 https://reactome.org/PathwayBrowser/#/R-MMU-5696183 AOC3 deaminates BZAM IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-6783880 https://reactome.org/PathwayBrowser/#/R-MMU-6783880 PIPOX oxidises PPCA to P6C IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-6786239 https://reactome.org/PathwayBrowser/#/R-MMU-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-6787811 https://reactome.org/PathwayBrowser/#/R-MMU-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Mus musculus 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-MMU-6789092 https://reactome.org/PathwayBrowser/#/R-MMU-6789092 NOX2 generates superoxide anion from oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-6807053 https://reactome.org/PathwayBrowser/#/R-MMU-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-6807214 https://reactome.org/PathwayBrowser/#/R-MMU-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-6807557 https://reactome.org/PathwayBrowser/#/R-MMU-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-6810076 https://reactome.org/PathwayBrowser/#/R-MMU-6810076 DDO oxidizes D-Asp to OA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-6814153 https://reactome.org/PathwayBrowser/#/R-MMU-6814153 ADO oxidises 2AET to HTAU IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71118 https://reactome.org/PathwayBrowser/#/R-MMU-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71163 https://reactome.org/PathwayBrowser/#/R-MMU-71163 HPD dioxygenates HPP IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71164 https://reactome.org/PathwayBrowser/#/R-MMU-71164 HGD dioxygenates homogentisate IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71188 https://reactome.org/PathwayBrowser/#/R-MMU-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71200 https://reactome.org/PathwayBrowser/#/R-MMU-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71218 https://reactome.org/PathwayBrowser/#/R-MMU-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-71241 https://reactome.org/PathwayBrowser/#/R-MMU-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-71261 https://reactome.org/PathwayBrowser/#/R-MMU-71261 BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-74247 https://reactome.org/PathwayBrowser/#/R-MMU-74247 XDH oxidizes hypoxanthine to form xanthine IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-74258 https://reactome.org/PathwayBrowser/#/R-MMU-74258 XDH oxidizes xanthine to form urate IEA Mus musculus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-MMU-76031 https://reactome.org/PathwayBrowser/#/R-MMU-76031 2 H2O2 => O2 + 2 H2O IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76354 https://reactome.org/PathwayBrowser/#/R-MMU-76354 Vinyl chloride is oxidized to 2-Chloroethylene oxide IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76373 https://reactome.org/PathwayBrowser/#/R-MMU-76373 N-hydroxylation of 4-aminobiphenyl IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76386 https://reactome.org/PathwayBrowser/#/R-MMU-76386 CYP1A2 S-demethylates 6MMP IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76397 https://reactome.org/PathwayBrowser/#/R-MMU-76397 Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76416 https://reactome.org/PathwayBrowser/#/R-MMU-76416 Benzene is hydroxylated to phenol IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76426 https://reactome.org/PathwayBrowser/#/R-MMU-76426 N-atom dealkylation of caffeine IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76453 https://reactome.org/PathwayBrowser/#/R-MMU-76453 Coumarin is 7-hydroxylated by CYP2A6 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76456 https://reactome.org/PathwayBrowser/#/R-MMU-76456 O-atom dealkylation of dextromethorphan IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76466 https://reactome.org/PathwayBrowser/#/R-MMU-76466 CYP4A11 12-hydroxylates DDCX IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76472 https://reactome.org/PathwayBrowser/#/R-MMU-76472 Ethylene is oxidized to Ethylene oxide by CYP1A1 IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-76475 https://reactome.org/PathwayBrowser/#/R-MMU-76475 Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide IEA Mus musculus 15379 R-ALL-5668566 O2 [melanosome lumen] R-MMU-8878581 https://reactome.org/PathwayBrowser/#/R-MMU-8878581 TYRP1 oxidises DHICA to IQCA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-888614 https://reactome.org/PathwayBrowser/#/R-MMU-888614 IDO2 dioxygenates L-Trp to NFK IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-8953398 https://reactome.org/PathwayBrowser/#/R-MMU-8953398 PIR oxygenates quercetin IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-8956458 https://reactome.org/PathwayBrowser/#/R-MMU-8956458 RNLS:FAD oxidises dh-beta-NAD to NAD+ IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-8981606 https://reactome.org/PathwayBrowser/#/R-MMU-8981606 Myoglobin binds oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-8981610 https://reactome.org/PathwayBrowser/#/R-MMU-8981610 Neuroglobin binds oxygen IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-8981621 https://reactome.org/PathwayBrowser/#/R-MMU-8981621 Neuroglobin:oxygen dissociates IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-8981622 https://reactome.org/PathwayBrowser/#/R-MMU-8981622 Myoglobin:oxygen dissociates IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-8982617 https://reactome.org/PathwayBrowser/#/R-MMU-8982617 CYGB:O2 dissociates IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018858 https://reactome.org/PathwayBrowser/#/R-MMU-9018858 ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018859 https://reactome.org/PathwayBrowser/#/R-MMU-9018859 ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018863 https://reactome.org/PathwayBrowser/#/R-MMU-9018863 ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018880 https://reactome.org/PathwayBrowser/#/R-MMU-9018880 Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018894 https://reactome.org/PathwayBrowser/#/R-MMU-9018894 ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9018907 https://reactome.org/PathwayBrowser/#/R-MMU-9018907 ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020251 https://reactome.org/PathwayBrowser/#/R-MMU-9020251 ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020259 https://reactome.org/PathwayBrowser/#/R-MMU-9020259 ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020261 https://reactome.org/PathwayBrowser/#/R-MMU-9020261 Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020264 https://reactome.org/PathwayBrowser/#/R-MMU-9020264 ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020274 https://reactome.org/PathwayBrowser/#/R-MMU-9020274 ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020275 https://reactome.org/PathwayBrowser/#/R-MMU-9020275 ALOX15 oxidises DHA to 17(S)-Hp-DHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020282 https://reactome.org/PathwayBrowser/#/R-MMU-9020282 ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9020610 https://reactome.org/PathwayBrowser/#/R-MMU-9020610 ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9024872 https://reactome.org/PathwayBrowser/#/R-MMU-9024872 ALOX15 oxidises 17(S)-Hp-DHA to PDX IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9024997 https://reactome.org/PathwayBrowser/#/R-MMU-9024997 ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9025152 https://reactome.org/PathwayBrowser/#/R-MMU-9025152 ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9025957 https://reactome.org/PathwayBrowser/#/R-MMU-9025957 ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9025996 https://reactome.org/PathwayBrowser/#/R-MMU-9025996 ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9026003 https://reactome.org/PathwayBrowser/#/R-MMU-9026003 ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9026005 https://reactome.org/PathwayBrowser/#/R-MMU-9026005 ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9026006 https://reactome.org/PathwayBrowser/#/R-MMU-9026006 ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9026405 https://reactome.org/PathwayBrowser/#/R-MMU-9026405 ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9026408 https://reactome.org/PathwayBrowser/#/R-MMU-9026408 PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027043 https://reactome.org/PathwayBrowser/#/R-MMU-9027043 CYPs hydroxylate DHA to 14(R)-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027302 https://reactome.org/PathwayBrowser/#/R-MMU-9027302 CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027321 https://reactome.org/PathwayBrowser/#/R-MMU-9027321 CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027532 https://reactome.org/PathwayBrowser/#/R-MMU-9027532 PTGS2 dimer oxidises DHA to 13-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027607 https://reactome.org/PathwayBrowser/#/R-MMU-9027607 Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027624 https://reactome.org/PathwayBrowser/#/R-MMU-9027624 ALOX5 oxidises DHA to 7-HDHA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027627 https://reactome.org/PathwayBrowser/#/R-MMU-9027627 Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027628 https://reactome.org/PathwayBrowser/#/R-MMU-9027628 ALOX5 oxidises EPA to 5-HEPE IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9027633 https://reactome.org/PathwayBrowser/#/R-MMU-9027633 ALOX5 oxidises DPAn-3 to 7-HDPAn-3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9028255 https://reactome.org/PathwayBrowser/#/R-MMU-9028255 PTGS2 dimer oxidises EPA to PGH3 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9037761 https://reactome.org/PathwayBrowser/#/R-MMU-9037761 CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-917891 https://reactome.org/PathwayBrowser/#/R-MMU-917891 SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-917933 https://reactome.org/PathwayBrowser/#/R-MMU-917933 SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9629578 https://reactome.org/PathwayBrowser/#/R-MMU-9629578 JMJD7 dimer hydroxlates a lysine residue of DRG2 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9629591 https://reactome.org/PathwayBrowser/#/R-MMU-9629591 JMJD7 dimer hydroxlates a lysine residue of DRG1 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9629869 https://reactome.org/PathwayBrowser/#/R-MMU-9629869 KDM8:Fe2+ hydroxylates an arginine residue of RPS6 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9629888 https://reactome.org/PathwayBrowser/#/R-MMU-9629888 KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9629946 https://reactome.org/PathwayBrowser/#/R-MMU-9629946 JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9630022 https://reactome.org/PathwayBrowser/#/R-MMU-9630022 JMJD6 dimer hydroxylates lysine residues of U2AF2 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9630769 https://reactome.org/PathwayBrowser/#/R-MMU-9630769 OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9630967 https://reactome.org/PathwayBrowser/#/R-MMU-9630967 RIOX2Fe2+ hydroxylates a histidine residue of RPL27A IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9630993 https://reactome.org/PathwayBrowser/#/R-MMU-9630993 RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-965019 https://reactome.org/PathwayBrowser/#/R-MMU-965019 2xPNPO:2xFMN oxidizes PDXP to PXLP IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-965079 https://reactome.org/PathwayBrowser/#/R-MMU-965079 2xPNPO:2xFMN oxidizes PXAP to PXLP IEA Mus musculus 15379 R-ALL-352327 O2 [extracellular region] R-MMU-9709360 https://reactome.org/PathwayBrowser/#/R-MMU-9709360 H2O2 reduces MetHb IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-9749986 https://reactome.org/PathwayBrowser/#/R-MMU-9749986 CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-9750016 https://reactome.org/PathwayBrowser/#/R-MMU-9750016 CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9753285 https://reactome.org/PathwayBrowser/#/R-MMU-9753285 CYP2E1 monooxygenates APAP to NAPQI IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9756138 https://reactome.org/PathwayBrowser/#/R-MMU-9756138 CYP3A4 monooxygenates ATVL to 2-OH-ATVL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9756162 https://reactome.org/PathwayBrowser/#/R-MMU-9756162 CYP3A4 monooxygenates ATV to 4-OH-ATV IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9756169 https://reactome.org/PathwayBrowser/#/R-MMU-9756169 CYP3A4 monooxygenates ATV to 2-OH-ATV IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9756180 https://reactome.org/PathwayBrowser/#/R-MMU-9756180 CYP3A4 monooxygenates ATVL to 4-OH-ATVL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-975635 https://reactome.org/PathwayBrowser/#/R-MMU-975635 BCMO1:Fe2+ cleaves betaC to atRAL IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9758674 https://reactome.org/PathwayBrowser/#/R-MMU-9758674 CYP3A4 oxidizes PREDN,PREDL IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9817463 https://reactome.org/PathwayBrowser/#/R-MMU-9817463 Tet3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 dimethylated on lysine-9 TAS Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-9817575 https://reactome.org/PathwayBrowser/#/R-MMU-9817575 ERO1B oxidizes P4HB IEA Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9822448 https://reactome.org/PathwayBrowser/#/R-MMU-9822448 Kdm5b demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9822463 https://reactome.org/PathwayBrowser/#/R-MMU-9822463 Kdm5a demethylates histone H3 trimethyllysine-4 (H3K4me3) TAS Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9822924 https://reactome.org/PathwayBrowser/#/R-MMU-9822924 Kdm6b (Jmjd3) demethylates histone H3 trimethyllysine-27 (H3K27me3) TAS Mus musculus 15379 R-ALL-113685 O2 [nucleoplasm] R-MMU-9822964 https://reactome.org/PathwayBrowser/#/R-MMU-9822964 Kdm6a (Utx) demethylates trimethylated histone H3 lysine-27 (H3K27me3) TAS Mus musculus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-MMU-9856718 https://reactome.org/PathwayBrowser/#/R-MMU-9856718 HPDL dioxygenates HPPA IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9915971 https://reactome.org/PathwayBrowser/#/R-MMU-9915971 Arachidonate is epoxidated to 11,12-EET by CYP(5) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-9915992 https://reactome.org/PathwayBrowser/#/R-MMU-9915992 Arachidonate is hydroxylated to 17-HETE by CYP(1) IEA Mus musculus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-MMU-9915993 https://reactome.org/PathwayBrowser/#/R-MMU-9915993 Arachidonate is hydroxylated to 18-HETE by CYP(1) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9915997 https://reactome.org/PathwayBrowser/#/R-MMU-9915997 Arachidonate is epoxidated to 14,15-EET by CYP(5) IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-MMU-9916401 https://reactome.org/PathwayBrowser/#/R-MMU-9916401 ALOX12 oxidises LTA4 to LXB4 IEA Mus musculus 15379 R-ALL-29368 O2 [cytosol] R-PFA-1497810 https://reactome.org/PathwayBrowser/#/R-PFA-1497810 Uncoupled eNOS favours the formation of superoxide IEA Plasmodium falciparum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-PFA-189421 https://reactome.org/PathwayBrowser/#/R-PFA-189421 CPO transforms COPRO3 to PPGEN9 IEA Plasmodium falciparum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-PFA-189423 https://reactome.org/PathwayBrowser/#/R-PFA-189423 PPO oxidises PPGEN9 to PRIN9 IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-PFA-202127 https://reactome.org/PathwayBrowser/#/R-PFA-202127 eNOS synthesizes NO IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-PFA-204662 https://reactome.org/PathwayBrowser/#/R-PFA-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Plasmodium falciparum 15379 R-ALL-352327 O2 [extracellular region] R-PFA-2160492 https://reactome.org/PathwayBrowser/#/R-PFA-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Plasmodium falciparum 15379 R-ALL-113685 O2 [nucleoplasm] R-PFA-2172678 https://reactome.org/PathwayBrowser/#/R-PFA-2172678 PHF8 demethylates histone H4K20me1 IEA Plasmodium falciparum 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-PFA-3341294 https://reactome.org/PathwayBrowser/#/R-PFA-3341294 Superoxide reduces cytochrome c IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-PFA-418436 https://reactome.org/PathwayBrowser/#/R-PFA-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Plasmodium falciparum 15379 R-ALL-113685 O2 [nucleoplasm] R-PFA-4724284 https://reactome.org/PathwayBrowser/#/R-PFA-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Plasmodium falciparum 15379 R-ALL-113685 O2 [nucleoplasm] R-PFA-5661115 https://reactome.org/PathwayBrowser/#/R-PFA-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-PFA-5690565 https://reactome.org/PathwayBrowser/#/R-PFA-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-PFA-8847579 https://reactome.org/PathwayBrowser/#/R-PFA-8847579 SCD5 desaturates ST-CoA to OLE-CoA IEA Plasmodium falciparum 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-PFA-9817575 https://reactome.org/PathwayBrowser/#/R-PFA-9817575 ERO1B oxidizes P4HB IEA Plasmodium falciparum 15379 R-ALL-29368 O2 [cytosol] R-RNO-1222376 https://reactome.org/PathwayBrowser/#/R-RNO-1222376 NOX2 generates superoxide from oxygen IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1234164 https://reactome.org/PathwayBrowser/#/R-RNO-1234164 Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-1234165 https://reactome.org/PathwayBrowser/#/R-RNO-1234165 Nuclear PHD1,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1234173 https://reactome.org/PathwayBrowser/#/R-RNO-1234173 Cytosolic PHD2,3 hydroxylates proline residues on HIF3A IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1234177 https://reactome.org/PathwayBrowser/#/R-RNO-1234177 Cytosolic PHD2,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-1234181 https://reactome.org/PathwayBrowser/#/R-RNO-1234181 Nuclear PHD1,3 hydroxylates proline residues on HIF1A IEA Rattus norvegicus 15379 R-ALL-1236709 O2 [phagolysosome] R-RNO-1236967 https://reactome.org/PathwayBrowser/#/R-RNO-1236967 Alkalization of the phagosomal lumen by NOX2 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1237119 https://reactome.org/PathwayBrowser/#/R-RNO-1237119 Acireductone is oxidized to MOB IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1237325 https://reactome.org/PathwayBrowser/#/R-RNO-1237325 Hemoglobin A is protonated and carbamated causing release of oxygen IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1247668 https://reactome.org/PathwayBrowser/#/R-RNO-1247668 Hemoglobin A binds O2, releasing H+ and CO2 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-139970 https://reactome.org/PathwayBrowser/#/R-RNO-139970 FMO3:FAD N-oxidises TMA to TMAO IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-140355 https://reactome.org/PathwayBrowser/#/R-RNO-140355 Arachidonate is oxidised to PGG2 by PTGS1 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-141186 https://reactome.org/PathwayBrowser/#/R-RNO-141186 MAOA:FAD oxidatively deaminates of 5HT IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-141200 https://reactome.org/PathwayBrowser/#/R-RNO-141200 MAOB:FAD oxidatively deaminates of PEA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-141202 https://reactome.org/PathwayBrowser/#/R-RNO-141202 MAOB:FAD oxidatively deaminates TYR IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-141341 https://reactome.org/PathwayBrowser/#/R-RNO-141341 SMOX-3 oxidises SPN to SPM IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-141348 https://reactome.org/PathwayBrowser/#/R-RNO-141348 PAO:FAD oxidises NASPM to PTCN IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-141351 https://reactome.org/PathwayBrowser/#/R-RNO-141351 PAOX:FAD oxidises NASPN to SPM IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-143468 https://reactome.org/PathwayBrowser/#/R-RNO-143468 MEOS oxidizes ethanol to acetaldehyde IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1497810 https://reactome.org/PathwayBrowser/#/R-RNO-1497810 Uncoupled eNOS favours the formation of superoxide IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1562626 https://reactome.org/PathwayBrowser/#/R-RNO-1562626 Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-156526 https://reactome.org/PathwayBrowser/#/R-RNO-156526 CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159752 https://reactome.org/PathwayBrowser/#/R-RNO-159752 GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159761 https://reactome.org/PathwayBrowser/#/R-RNO-159761 GGCX gamma-carboxylates F7(21-466) (pro-factor VII) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159795 https://reactome.org/PathwayBrowser/#/R-RNO-159795 GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159803 https://reactome.org/PathwayBrowser/#/R-RNO-159803 GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159819 https://reactome.org/PathwayBrowser/#/R-RNO-159819 GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-159826 https://reactome.org/PathwayBrowser/#/R-RNO-159826 GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-1614544 https://reactome.org/PathwayBrowser/#/R-RNO-1614544 Sulfite is oxidized to sulfate IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-1614605 https://reactome.org/PathwayBrowser/#/R-RNO-1614605 Persulfide sulfur is dioxygenated IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1614645 https://reactome.org/PathwayBrowser/#/R-RNO-1614645 CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-163214 https://reactome.org/PathwayBrowser/#/R-RNO-163214 Electron transfer from reduced cytochrome c to molecular oxygen IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-163820 https://reactome.org/PathwayBrowser/#/R-RNO-163820 GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-1650808 https://reactome.org/PathwayBrowser/#/R-RNO-1650808 Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-1655453 https://reactome.org/PathwayBrowser/#/R-RNO-1655453 FMO1:FAD oxidizes HTAU to TAU IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-189398 https://reactome.org/PathwayBrowser/#/R-RNO-189398 HMOX1 dimer, HMOX2 cleave heme IEA Rattus norvegicus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-RNO-189421 https://reactome.org/PathwayBrowser/#/R-RNO-189421 CPO transforms COPRO3 to PPGEN9 IEA Rattus norvegicus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-RNO-189423 https://reactome.org/PathwayBrowser/#/R-RNO-189423 PPO oxidises PPGEN9 to PRIN9 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-191299 https://reactome.org/PathwayBrowser/#/R-RNO-191299 Squalene is oxidized to its epoxide IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-191972 https://reactome.org/PathwayBrowser/#/R-RNO-191972 27-hydroxycholesterol is 7alpha-hydroxylated IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-191983 https://reactome.org/PathwayBrowser/#/R-RNO-191983 Cholesterol is hydroxylated to 25-hydroxycholesterol IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-191999 https://reactome.org/PathwayBrowser/#/R-RNO-191999 CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-192051 https://reactome.org/PathwayBrowser/#/R-RNO-192051 CYP7A1 7-hydroxylates CHOL IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-192054 https://reactome.org/PathwayBrowser/#/R-RNO-192054 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-192061 https://reactome.org/PathwayBrowser/#/R-RNO-192061 CYP46A1 24-hydroxylates CHOL IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-192065 https://reactome.org/PathwayBrowser/#/R-RNO-192065 CYP7B1 7-hydroxylates 25OH-CHOL IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-192123 https://reactome.org/PathwayBrowser/#/R-RNO-192123 CYP27A1 27-hydroxylates CHOL IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-192157 https://reactome.org/PathwayBrowser/#/R-RNO-192157 CYP8B1 12-hydroxylates 4CHOL7aOLONE IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-192178 https://reactome.org/PathwayBrowser/#/R-RNO-192178 CYP39A1 7-hydroxylates 24OH-CHOL IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-192335 https://reactome.org/PathwayBrowser/#/R-RNO-192335 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193054 https://reactome.org/PathwayBrowser/#/R-RNO-193054 Oxidation of cholesterol to 22beta-hydroxycholesterol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193060 https://reactome.org/PathwayBrowser/#/R-RNO-193060 CYP19A1 hydroxylates ANDST to E1 IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193065 https://reactome.org/PathwayBrowser/#/R-RNO-193065 Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193068 https://reactome.org/PathwayBrowser/#/R-RNO-193068 CYP17A1 17-hydroxylates PREG IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193070 https://reactome.org/PathwayBrowser/#/R-RNO-193070 CYP17A1 cleaves 17aHPREG to DHA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193072 https://reactome.org/PathwayBrowser/#/R-RNO-193072 CYP17A1 17-hydroxylates P4 to 17aHPROG IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193099 https://reactome.org/PathwayBrowser/#/R-RNO-193099 CYP17A1 cleaves 17aHPROG to ANDST IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193101 https://reactome.org/PathwayBrowser/#/R-RNO-193101 CYP11A1 cleaves 20a,22b-DHCHOL IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193143 https://reactome.org/PathwayBrowser/#/R-RNO-193143 CYP19A1 hydroxylates TEST to EST17b IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-193369 https://reactome.org/PathwayBrowser/#/R-RNO-193369 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193393 https://reactome.org/PathwayBrowser/#/R-RNO-193393 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193460 https://reactome.org/PathwayBrowser/#/R-RNO-193460 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193709 https://reactome.org/PathwayBrowser/#/R-RNO-193709 CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193713 https://reactome.org/PathwayBrowser/#/R-RNO-193713 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193719 https://reactome.org/PathwayBrowser/#/R-RNO-193719 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193737 https://reactome.org/PathwayBrowser/#/R-RNO-193737 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193780 https://reactome.org/PathwayBrowser/#/R-RNO-193780 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193787 https://reactome.org/PathwayBrowser/#/R-RNO-193787 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193792 https://reactome.org/PathwayBrowser/#/R-RNO-193792 CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193845 https://reactome.org/PathwayBrowser/#/R-RNO-193845 CYP8B1 12-hydroxylates 4CHOL7a,27DONE IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193964 https://reactome.org/PathwayBrowser/#/R-RNO-193964 CYP21A2 21-hydroxylates PROG IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193965 https://reactome.org/PathwayBrowser/#/R-RNO-193965 CYP11B2 oxidises 18HCORST to ALDO IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-193981 https://reactome.org/PathwayBrowser/#/R-RNO-193981 CYP21A2 oxidises 17HPROG IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193995 https://reactome.org/PathwayBrowser/#/R-RNO-193995 CYP11B2 18-hydroxylates CORST to 18HCORST IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-193997 https://reactome.org/PathwayBrowser/#/R-RNO-193997 CYP11B1 oxidises 11DCORT IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-194017 https://reactome.org/PathwayBrowser/#/R-RNO-194017 CYP11B2 oxidises 11DCORST to CORST IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-194641 https://reactome.org/PathwayBrowser/#/R-RNO-194641 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-194669 https://reactome.org/PathwayBrowser/#/R-RNO-194669 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-194678 https://reactome.org/PathwayBrowser/#/R-RNO-194678 CYP51A1 demethylates LNSOL IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-195664 https://reactome.org/PathwayBrowser/#/R-RNO-195664 Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-1980233 https://reactome.org/PathwayBrowser/#/R-RNO-1980233 Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-1981104 https://reactome.org/PathwayBrowser/#/R-RNO-1981104 Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-198563 https://reactome.org/PathwayBrowser/#/R-RNO-198563 IDO1 dioxygenates L-Trp to NFK IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2002466 https://reactome.org/PathwayBrowser/#/R-RNO-2002466 Formation of allysine by LOX IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-202127 https://reactome.org/PathwayBrowser/#/R-RNO-202127 eNOS synthesizes NO IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046084 https://reactome.org/PathwayBrowser/#/R-RNO-2046084 Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046089 https://reactome.org/PathwayBrowser/#/R-RNO-2046089 Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046091 https://reactome.org/PathwayBrowser/#/R-RNO-2046091 Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA TAS Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046092 https://reactome.org/PathwayBrowser/#/R-RNO-2046092 Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046096 https://reactome.org/PathwayBrowser/#/R-RNO-2046096 Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2046097 https://reactome.org/PathwayBrowser/#/R-RNO-2046097 Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-204662 https://reactome.org/PathwayBrowser/#/R-RNO-204662 DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-2066787 https://reactome.org/PathwayBrowser/#/R-RNO-2066787 Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-209765 https://reactome.org/PathwayBrowser/#/R-RNO-209765 CYP24A1 hydroxylates 1,25(OH)2D, inactivating it IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-209823 https://reactome.org/PathwayBrowser/#/R-RNO-209823 Tyrosine is hydroxylated to dopa IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-209828 https://reactome.org/PathwayBrowser/#/R-RNO-209828 Tryptophan is hydroxylated IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-209845 https://reactome.org/PathwayBrowser/#/R-RNO-209845 CYP2R1 25-hydroxylates VD3 to 25(OH)D IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-209868 https://reactome.org/PathwayBrowser/#/R-RNO-209868 CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D IEA Rattus norvegicus 15379 R-ALL-351593 O2 [secretory granule lumen] R-RNO-209891 https://reactome.org/PathwayBrowser/#/R-RNO-209891 Dopamine is oxidised to noradrenaline IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-211873 https://reactome.org/PathwayBrowser/#/R-RNO-211873 CYP4F2, 4F3 20-hydroxylate LTB4 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211874 https://reactome.org/PathwayBrowser/#/R-RNO-211874 CYP2S1 4-hydroxylates atRA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211881 https://reactome.org/PathwayBrowser/#/R-RNO-211881 Coumarin is 7-hydroxylated by CYP2A13 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211882 https://reactome.org/PathwayBrowser/#/R-RNO-211882 CYP3A7 can 6beta-hydroxylate testosterone IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211904 https://reactome.org/PathwayBrowser/#/R-RNO-211904 CYP4F12 18-hydroxylates ARA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211910 https://reactome.org/PathwayBrowser/#/R-RNO-211910 CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211919 https://reactome.org/PathwayBrowser/#/R-RNO-211919 CYP4F8 19-hydroxylates PGH2 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-211923 https://reactome.org/PathwayBrowser/#/R-RNO-211923 CYP26C1 4-hydroxylates 9cRA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211924 https://reactome.org/PathwayBrowser/#/R-RNO-211924 CYP4B1 12-hydroxylates ARA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211929 https://reactome.org/PathwayBrowser/#/R-RNO-211929 CYP2C19 5-hydroxylates omeprazole IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211948 https://reactome.org/PathwayBrowser/#/R-RNO-211948 CYP3A4 can N-demethylate loperamide IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-211950 https://reactome.org/PathwayBrowser/#/R-RNO-211950 CYP24A1 24-hydroxylates CTL IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-211951 https://reactome.org/PathwayBrowser/#/R-RNO-211951 CYP1B1 4-hydroxylates EST17b IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211959 https://reactome.org/PathwayBrowser/#/R-RNO-211959 CYP3A43 6b-hydroxylates TEST IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211960 https://reactome.org/PathwayBrowser/#/R-RNO-211960 CYP2U1 19-hydroxylates ARA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211962 https://reactome.org/PathwayBrowser/#/R-RNO-211962 CYP4F11 16-hydroxylates 3OH-PALM IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211966 https://reactome.org/PathwayBrowser/#/R-RNO-211966 CYP2D6 4-hydroxylates debrisoquine IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211968 https://reactome.org/PathwayBrowser/#/R-RNO-211968 CYP2W1 oxidises INDOL IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211983 https://reactome.org/PathwayBrowser/#/R-RNO-211983 CYP2J2 oxidises ARA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211988 https://reactome.org/PathwayBrowser/#/R-RNO-211988 CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-211991 https://reactome.org/PathwayBrowser/#/R-RNO-211991 Cyclophosphamide is 4-hydroxylated by CYP2B6 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-212004 https://reactome.org/PathwayBrowser/#/R-RNO-212004 CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-212005 https://reactome.org/PathwayBrowser/#/R-RNO-212005 CYP2F1 dehydrogenates 3-methylindole IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-212007 https://reactome.org/PathwayBrowser/#/R-RNO-212007 CYP26A1,B1 4-hydroxylate atRA IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-213175 https://reactome.org/PathwayBrowser/#/R-RNO-213175 CYP3A4,5 oxidise AFB1 to AFXBO IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-215526 https://reactome.org/PathwayBrowser/#/R-RNO-215526 CYP4F3 20-hydroxylates LTB4 IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2160492 https://reactome.org/PathwayBrowser/#/R-RNO-2160492 IL4I1:FAD oxidises L-Phe to kPPV IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161745 https://reactome.org/PathwayBrowser/#/R-RNO-2161745 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161775 https://reactome.org/PathwayBrowser/#/R-RNO-2161775 ALOX12 oxidises LTA4 to LXA4 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161792 https://reactome.org/PathwayBrowser/#/R-RNO-2161792 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161794 https://reactome.org/PathwayBrowser/#/R-RNO-2161794 Arachidonate is converted to HXA3/B3 by ALOX12 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2161795 https://reactome.org/PathwayBrowser/#/R-RNO-2161795 Arachidonate is hydroxylated to 16-HETE by CYP(1) IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2161814 https://reactome.org/PathwayBrowser/#/R-RNO-2161814 Arachidonate is hydroxylated to 19-HETE by CYP(2) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161890 https://reactome.org/PathwayBrowser/#/R-RNO-2161890 Arachidonate is epoxidated to 5,6-EET by CYP(4) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161899 https://reactome.org/PathwayBrowser/#/R-RNO-2161899 Arachidonate is epoxidated to 8,9-EET by CYP(5) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161907 https://reactome.org/PathwayBrowser/#/R-RNO-2161907 ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161917 https://reactome.org/PathwayBrowser/#/R-RNO-2161917 ALOX5 oxidises 15S-HpETE to LXA4/B4 IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2161940 https://reactome.org/PathwayBrowser/#/R-RNO-2161940 Arachidonate is hydroxylated to 20-HETE by CYP(3) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161950 https://reactome.org/PathwayBrowser/#/R-RNO-2161950 Arachidonate is oxidised to 12R-HpETE by ALOX12B IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161951 https://reactome.org/PathwayBrowser/#/R-RNO-2161951 Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2161964 https://reactome.org/PathwayBrowser/#/R-RNO-2161964 Arachidonate is oxidised to 12S-HpETE by ALOX12/15 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-2162002 https://reactome.org/PathwayBrowser/#/R-RNO-2162002 Arachidonate is oxidised to 15S-HpETE by ALOX15/15B IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-2162187 https://reactome.org/PathwayBrowser/#/R-RNO-2162187 COQ6 hydroxylates DHB IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-2162194 https://reactome.org/PathwayBrowser/#/R-RNO-2162194 COQ7:COQ9 octamer hydroxylates DMQ10H2 IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2168883 https://reactome.org/PathwayBrowser/#/R-RNO-2168883 Haptoglobin:Hemoglobin binds CD163 IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2168885 https://reactome.org/PathwayBrowser/#/R-RNO-2168885 Haptoglobin binds Hemoglobin IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2168889 https://reactome.org/PathwayBrowser/#/R-RNO-2168889 Haptoglobin-related Protein binds Hemoglobin IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-217255 https://reactome.org/PathwayBrowser/#/R-RNO-217255 FMO1:FAD N-oxidises TAM IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-217258 https://reactome.org/PathwayBrowser/#/R-RNO-217258 FMO2:FAD:Mg2+ S-oxidises MTZ IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-2172678 https://reactome.org/PathwayBrowser/#/R-RNO-2172678 PHF8 demethylates histone H4K20me1 IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2230938 https://reactome.org/PathwayBrowser/#/R-RNO-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Rattus norvegicus 15379 R-ALL-2230955 O2 [endocytic vesicle lumen] R-RNO-2230938 https://reactome.org/PathwayBrowser/#/R-RNO-2230938 Hemoglobin:Haptoglobin:CD163 is endocytosed IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-2309787 https://reactome.org/PathwayBrowser/#/R-RNO-2309787 Arachidonate is oxidised to PGG2 by PTGS2 IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-2395340 https://reactome.org/PathwayBrowser/#/R-RNO-2395340 Formation of hydroxyallysine by LOX IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-265296 https://reactome.org/PathwayBrowser/#/R-RNO-265296 Arachidonate is oxidised to 5S-HpETE by ALOX5 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-3204311 https://reactome.org/PathwayBrowser/#/R-RNO-3204311 AOX1 oxidises PXL to PDXate IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-3299680 https://reactome.org/PathwayBrowser/#/R-RNO-3299680 SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-3299682 https://reactome.org/PathwayBrowser/#/R-RNO-3299682 SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-3299691 https://reactome.org/PathwayBrowser/#/R-RNO-3299691 SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) IEA Rattus norvegicus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-RNO-3341294 https://reactome.org/PathwayBrowser/#/R-RNO-3341294 Superoxide reduces cytochrome c IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-374909 https://reactome.org/PathwayBrowser/#/R-RNO-374909 Catabolism of Noradrenaline IEA Rattus norvegicus 15379 R-ALL-189461 O2 [mitochondrial intermembrane space] R-RNO-3777112 https://reactome.org/PathwayBrowser/#/R-RNO-3777112 SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-379382 https://reactome.org/PathwayBrowser/#/R-RNO-379382 MAOA:FAD deaminates DA to DOPAC IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-379395 https://reactome.org/PathwayBrowser/#/R-RNO-379395 MAOA:FAD deaminates 3MT to HVA IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389639 https://reactome.org/PathwayBrowser/#/R-RNO-389639 phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389821 https://reactome.org/PathwayBrowser/#/R-RNO-389821 glycine + O2 => glyoxylate + H2O2 + NH4+ IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389842 https://reactome.org/PathwayBrowser/#/R-RNO-389842 HAO1 tetramer oxidizes glycolate to glyoxylate IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389862 https://reactome.org/PathwayBrowser/#/R-RNO-389862 Conversion of glyoxylate to oxalate IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389889 https://reactome.org/PathwayBrowser/#/R-RNO-389889 ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-389891 https://reactome.org/PathwayBrowser/#/R-RNO-389891 (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-390256 https://reactome.org/PathwayBrowser/#/R-RNO-390256 ACOX1 oxidizes C26:0 CoA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-418436 https://reactome.org/PathwayBrowser/#/R-RNO-418436 Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-428259 https://reactome.org/PathwayBrowser/#/R-RNO-428259 DEGS1 dehydrogenates dihydroceramide IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-428260 https://reactome.org/PathwayBrowser/#/R-RNO-428260 DEGS2 oxygenates dihydroceramide IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4722133 https://reactome.org/PathwayBrowser/#/R-RNO-4722133 KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4724279 https://reactome.org/PathwayBrowser/#/R-RNO-4724279 KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4724284 https://reactome.org/PathwayBrowser/#/R-RNO-4724284 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4754176 https://reactome.org/PathwayBrowser/#/R-RNO-4754176 JMJD6 demethylates MeR3-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4754181 https://reactome.org/PathwayBrowser/#/R-RNO-4754181 KDM5A-D demethylate Me2K5-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-4754187 https://reactome.org/PathwayBrowser/#/R-RNO-4754187 KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-5164399 https://reactome.org/PathwayBrowser/#/R-RNO-5164399 BCO2:Fe2+ cleaves betaC to APO10al and bION IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5218841 https://reactome.org/PathwayBrowser/#/R-RNO-5218841 NADPH oxidase 2 generates superoxide from oxygen IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5340214 https://reactome.org/PathwayBrowser/#/R-RNO-5340214 CYGB binds O2 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5340226 https://reactome.org/PathwayBrowser/#/R-RNO-5340226 CYGB dioxygenates NO IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5362525 https://reactome.org/PathwayBrowser/#/R-RNO-5362525 CYP26A1,B1,C1 4-hydroxylate atRA IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5423117 https://reactome.org/PathwayBrowser/#/R-RNO-5423117 PHF8 demethylates MeK21-histone H4 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5423647 https://reactome.org/PathwayBrowser/#/R-RNO-5423647 CYP2A13 oxidises AFM1 to AFM1E IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5423664 https://reactome.org/PathwayBrowser/#/R-RNO-5423664 CYP3A4,5 hydroxylates AFB1 to AFQ1 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5423672 https://reactome.org/PathwayBrowser/#/R-RNO-5423672 CYP1A2, 3A4 oxidise AFB1 to AFNBO IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5423678 https://reactome.org/PathwayBrowser/#/R-RNO-5423678 CYP1A2 hydroxylates AFB1 to AFM1 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5625797 https://reactome.org/PathwayBrowser/#/R-RNO-5625797 KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5625848 https://reactome.org/PathwayBrowser/#/R-RNO-5625848 KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5625870 https://reactome.org/PathwayBrowser/#/R-RNO-5625870 KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661114 https://reactome.org/PathwayBrowser/#/R-RNO-5661114 KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661115 https://reactome.org/PathwayBrowser/#/R-RNO-5661115 KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661116 https://reactome.org/PathwayBrowser/#/R-RNO-5661116 KDM5A-D demethylate Me3K5-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661120 https://reactome.org/PathwayBrowser/#/R-RNO-5661120 KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661121 https://reactome.org/PathwayBrowser/#/R-RNO-5661121 KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661122 https://reactome.org/PathwayBrowser/#/R-RNO-5661122 JMJD6 demethylates Me2R3-histone H3 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661124 https://reactome.org/PathwayBrowser/#/R-RNO-5661124 JMJD6 demethylates MeR4-HIST1H4 IEA Rattus norvegicus 15379 R-ALL-113685 O2 [nucleoplasm] R-RNO-5661125 https://reactome.org/PathwayBrowser/#/R-RNO-5661125 JMJD6 demethylates Me2sR4-HIST1H4 IEA Rattus norvegicus 15379 R-ALL-5668566 O2 [melanosome lumen] R-RNO-5662692 https://reactome.org/PathwayBrowser/#/R-RNO-5662692 Dopa is oxidized to dopaquinone by TYR IEA Rattus norvegicus 15379 R-ALL-1236709 O2 [phagolysosome] R-RNO-5668629 https://reactome.org/PathwayBrowser/#/R-RNO-5668629 Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5668718 https://reactome.org/PathwayBrowser/#/R-RNO-5668718 NOX1 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5668731 https://reactome.org/PathwayBrowser/#/R-RNO-5668731 NOX3 complex:RAC1:GTP generates superoxide from oxygen IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5678327 https://reactome.org/PathwayBrowser/#/R-RNO-5678327 MIOX oxidises Ins to GlcA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5690565 https://reactome.org/PathwayBrowser/#/R-RNO-5690565 SCD desaturates ST-CoA to OLE-CoA IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-5691107 https://reactome.org/PathwayBrowser/#/R-RNO-5691107 FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5693681 https://reactome.org/PathwayBrowser/#/R-RNO-5693681 DUOX1,2 reduce O2 to H2O2 IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5693761 https://reactome.org/PathwayBrowser/#/R-RNO-5693761 FA2H hydroxylates 1,2-saturated fatty acids IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-5696119 https://reactome.org/PathwayBrowser/#/R-RNO-5696119 AGMO cleaves alkylglycerol into fatty aldehyde and glycerol IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5696131 https://reactome.org/PathwayBrowser/#/R-RNO-5696131 AOC1 deaminates Hist IEA Rattus norvegicus 15379 R-ALL-352327 O2 [extracellular region] R-RNO-5696183 https://reactome.org/PathwayBrowser/#/R-RNO-5696183 AOC3 deaminates BZAM IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-6783880 https://reactome.org/PathwayBrowser/#/R-RNO-6783880 PIPOX oxidises PPCA to P6C IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-6786239 https://reactome.org/PathwayBrowser/#/R-RNO-6786239 CYP4V2 omega-hydroxylates DHA to HDoHE IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-6787811 https://reactome.org/PathwayBrowser/#/R-RNO-6787811 HAO2 tetramer oxidises 2OH-PALM IEA Rattus norvegicus 15379 R-ALL-1222561 O2 [phagocytic vesicle lumen] R-RNO-6789092 https://reactome.org/PathwayBrowser/#/R-RNO-6789092 NOX2 generates superoxide anion from oxygen IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-6807053 https://reactome.org/PathwayBrowser/#/R-RNO-6807053 SC5D desaturates LTHSOL to 7-dehydroCHOL IEA Rattus norvegicus 15379 R-ALL-113534 O2 [endoplasmic reticulum lumen] R-RNO-6807214 https://reactome.org/PathwayBrowser/#/R-RNO-6807214 GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-6807557 https://reactome.org/PathwayBrowser/#/R-RNO-6807557 NOX4, NOX5 reduce O2 to O2.- IEA Rattus norvegicus 15379 R-ALL-113535 O2 [peroxisomal matrix] R-RNO-6810076 https://reactome.org/PathwayBrowser/#/R-RNO-6810076 DDO oxidizes D-Asp to OA IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-6814153 https://reactome.org/PathwayBrowser/#/R-RNO-6814153 ADO oxidises 2AET to HTAU IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71118 https://reactome.org/PathwayBrowser/#/R-RNO-71118 PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71163 https://reactome.org/PathwayBrowser/#/R-RNO-71163 HPD dioxygenates HPP IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71164 https://reactome.org/PathwayBrowser/#/R-RNO-71164 HGD dioxygenates homogentisate IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71188 https://reactome.org/PathwayBrowser/#/R-RNO-71188 TDO tetramer dioxygenates L-Trp to NFK IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71200 https://reactome.org/PathwayBrowser/#/R-RNO-71200 kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O IEA Rattus norvegicus 15379 R-ALL-29368 O2 [cytosol] R-RNO-71218 https://reactome.org/PathwayBrowser/#/R-RNO-71218 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde IEA Rattus norvegicus 15379 R-ALL-113533 O2 [mitochondrial matrix] R-RNO-71241 https://reactome.org/PathwayBrowser/#/R-RNO-71241 TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA IEA Rattus nor