The "Reactome to OMIM" file comprises of a tab-separated table provide supporting annotations to establish links from OMIM to Reactome pathways using isoform information in UniProt. The "Reactome to OMIM" file consists of three columns defining the pathways in the "lower levels" of the pathway hierarchy where the PhysicalEntity for the given UniProt accession can be found. The first column provides the UniProt accession (Acc), whereas the second and third column provides the pathway stable identifier (PathwayId), and the name of the pathway (Pathway), respectively.