Identifier | Name |
---|---|
9855905 | Positive gene expression regulation by 'pT153 USF1 dimer:TYR promoter [nucleoplasm]' The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression |
9851042 | Positive gene expression regulation by 'pY-STAT3:IRF4 gene [nucleoplasm]' IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas |
9835535 | Positive gene expression regulation by 'tcf7l1:ctnnb1:gbx2 gene [nucleoplasm]' The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction |
9835815 | Positive gene expression regulation by 'tfap2a:pax3 gene [nucleoplasm]' Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory network |
9642316 | Positive regulation by '2xp-STAT3 [nucleoplasm]' Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease |
9765929 | Positive regulation by '8:IL17RA [extracellular region]' ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway |
9641886 | Positive regulation by 'ACTIVIN [extracellular region]' Pituitary actions of ligands of the TGF-beta family: activins and inhibins |
9641228 | Positive regulation by 'ADP [mitochondrial matrix]' Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations |
9641624 | Positive regulation by 'AGER ligands:AGER [plasma membrane]' Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB |
9642202 | Positive regulation by 'AHCYL2 [cytosol]' AHCYL2 (long-IRBIT) as a potential regulator of the electrogenic Na(+)-HCO3(-) cotransporter NBCe1-B |
9641435 | Positive regulation by 'AMOT proteins [cytosol]' Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor |
9641983 | Positive regulation by 'AMOT proteins [cytosol]' Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein |
9642708 | Positive regulation by 'ANGPTL4 [extracellular region]' Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue |
9641804 | Positive regulation by 'ANGPTL4 [extracellular region]' Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue |
9641359 | Positive regulation by 'APP(672-713) [extracellular region]' Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture |
9642769 | Positive regulation by 'AS160:IRAP [cytoplasmic vesicle membrane]' AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain |
9853673 | Positive regulation by 'ATP [mitochondrial matrix]' Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site |
9641597 | Positive regulation by 'ATP2A1-3 [endoplasmic reticulum membrane]' Ca(2+)-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila |
9642209 | Positive regulation by 'AcCho [extracellular region]' Biology of incretins: GLP-1 and GIP |
9730730 | Positive regulation by 'Active ALK dimer [plasma membrane]' Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells |
9642946 | Positive regulation by 'As160 [cytoplasmic vesicle membrane]' Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane |
9641454 | Positive regulation by 'AscH- [nucleoplasm]' Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine |
9641595 | Positive regulation by 'AscH- [nucleoplasm]' Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine |
9642141 | Positive regulation by 'BBS/CCT complex [cytosol]' BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly |
9641791 | Positive regulation by 'BMP2 dimer [extracellular region]' Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter |
9642221 | Positive regulation by 'BMP2 dimer [extracellular region]' Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis |
9641999 | Positive regulation by 'BRCA1 [nucleoplasm]' Brca1 in immunoglobulin gene conversion and somatic hypermutation |
9642524 | Positive regulation by 'BRCA2 [nucleoplasm]' Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2 |
9642480 | Positive regulation by 'BRWD1:AcK9,14-p-S10-histone H3.1 [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus |
9642403 | Positive regulation by 'BRWD1:AcK9,14-pS10-histone H3 [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus |
9641346 | Positive regulation by 'Bmp2 dimer [extracellular region]' Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter |
9642766 | Positive regulation by 'CABLES1 [nucleoplasm]' Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers |
9641985 | Positive regulation by 'CABLES1 [nucleoplasm]' Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers |
9672332 | Positive regulation by 'CABP1 [plasma membrane]' Ca2+-binding proteins tune Ca2+-feedback to Cav1.3 channels in mouse auditory hair cells |
9672335 | Positive regulation by 'CABP2 [plasma membrane]' Ca2+-binding proteins tune Ca2+-feedback to Cav1.3 channels in mouse auditory hair cells |
9641320 | Positive regulation by 'CAK [nucleoplasm]' Targeting transcription regulation in cancer with a covalent CDK7 inhibitor |
9641254 | Positive regulation by 'CD209:ManLAM [plasma membrane]' C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB |
9642922 | Positive regulation by 'CEACAM heterodimer [plasma membrane]' GPI-anchored CEA family glycoproteins CEA and CEACAM6 mediate their biological effects through enhanced integrin alpha5beta1-fibronectin interaction |
9644098 | Positive regulation by 'CEBPA [nucleoplasm]' Autoregulation of the human C/EBP alpha gene by stimulation of upstream stimulatory factor binding |
9641601 | Positive regulation by 'CEBPA [nucleoplasm]' Phosphorylation of CCAAT/enhancer-binding protein alpha regulates GLUT4 expression and glucose transport in adipocytes |
9642850 | Positive regulation by 'CISH gene, SOCS1 gene, SOCS2 gene:p-STAT5 dimer [nucleoplasm]' Suppressor of cytokine signaling (SOCS) proteins are induced by IL-7 and target surface CD127 protein for degradation in human CD8 T cells |
9641512 | Positive regulation by 'CIT [cytosol]' Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate |
9845034 | Positive regulation by 'CLIP1(1-1083)-p-6Y LTK(488-864) fusion dimer [plasma membrane]' The CLIP1-LTK fusion is an oncogenic driverĀ in non-small-cell lung cancer |
9641869 | Positive regulation by 'Ca-P60A [endoplasmic reticulum membrane]' Ca(2+)-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila |
9641440 | Positive regulation by 'Ca2+ [cytosol]' 0121227022 Boyer, PD Phosphorylase kinase The Enzymes 3rd ed |
9839185 | Positive regulation by 'Ca2+ [cytosol]' Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C |
9839205 | Positive regulation by 'Ca2+ [cytosol]' Epidermal differentiation: the bare essentials |
9727658 | Positive regulation by 'Ca2+ [cytosol]' Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid |
9671760 | Positive regulation by 'Ca2+ [extracellular region]' Characterization of factor VII association with tissue factor in solution. High and low affinity calcium binding sites in factor VII contribute to functionally distinct interactions |
9671030 | Positive regulation by 'Ca2+ [extracellular region]' High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity |
9641489 | Positive regulation by 'Ccnd1:Crebbp:Notch1 Gene [nucleoplasm]' Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen |
9641868 | Positive regulation by 'Cdh1:phospho-APC/C complex [nucleoplasm]' DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells |
9641444 | Positive regulation by 'Cdh1:phospho-APC/C complex [nucleoplasm]' DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells |
9642977 | Positive regulation by 'Cebpa [nucleoplasm]' Sequential gene promoter interactions of C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis |
9642232 | Positive regulation by 'Cebpb [nucleoplasm]' Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade |
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