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Graph Database :: Data Schema

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Entries: EntityFunctionalStatus
Identifier Name
6802869 gain_of_function of RAS:GTP: inactive p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6802871 gain_of_function of RAS:GTP:inactive p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6803235 gain_of_function of RAS:GTP:inactive p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane]
6802872 gain_of_function of RAS:GTP:moderate kinase activity BRAF mutants:RAF:YWHAB [plasma membrane]
6802874 gain_of_function of RAS:GTP:moderate kinase activity BRAF mutants:p-RAF:YWHAB [plasma membrane]
6802877 gain_of_function of RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6802879 gain_of_function of RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6803228 gain_of_function of RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane]
9630074 gain_of_function of SHH processing variants:ERLEC:OS9:SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
9630076 gain_of_function of SHH processing variants:OS9/ERLEC1 [endoplasmic reticulum lumen]
5362402 gain_of_function of SHH variants [endoplasmic reticulum lumen]
2775820 gain_of_function of Ub-DLL/JAG:NOTCH1 PEST Domain Mutants [plasma membrane]
6802906 gain_of_function of V600E BRAF splice variants [cytosol]
9656196 gain_of_function of activated RAF1 mutant:scaffold:MAP2K:MAPK complex [plasma membrane]
9656199 gain_of_function of activated RAF1 mutant:scaffold:p-2S MAP2K:MAPK complex [plasma membrane]
9656200 gain_of_function of activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane]
9630097 gain_of_function of capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm]
8936728 gain_of_function of chemically or genetically inactive BRAF mutants:mutant RAS:GTP [plasma membrane]
5654536 gain_of_function of cytosolic FGFR1 fusion mutant dimers [cytosol]
5654483 gain_of_function of cytosolic FGFR1 fusion mutants [cytosol]
9673676 gain_of_function of cytosolic PDGFR fusion dimers [cytosol]
9673668 gain_of_function of cytosolic PDGFR fusions [cytosol]
9630091 gain_of_function of cytosolic p-FGFR1 fusion mutant dimers [cytosol]
5654506 gain_of_function of cytosolic p-FGFR1 fusion mutant dimers [cytosol]
9672154 gain_of_function of extracellular domain mutant PDGFRA dimers [endoplasmic reticulum membrane]
9672156 gain_of_function of extracellular domain mutant PDGFRA dimers [endoplasmic reticulum membrane]
9680251 gain_of_function of extracellular domain mutant dimers of KIT [plasma membrane]
9680254 gain_of_function of extracellular domain mutants of KIT [plasma membrane]
9670057 gain_of_function of factor VIIIa with defective A1 domain [extracellular region]
9670056 gain_of_function of factor VIIIa with defective A2 domain [extracellular region]
6802880 gain_of_function of genetically or chemically inactive BRAF [cytosol]
6802883 gain_of_function of high kinase activity BRAF mutants [cytosol]
6802885 gain_of_function of high kinase activity BRAF mutants:scaffold:MAP2K:MAPK complex [cytosol]
6802887 gain_of_function of high kinase activity BRAF mutants:scaffold:p-2S MAP2K:MAPK complex [cytosol]
6803226 gain_of_function of high kinase activity BRAF mutants:scaffold:p-2S MAP2K:p-T,Y MAPK complex [cytosol]
9669908 gain_of_function of juxtamembrane domain KIT mutant dimers [plasma membrane]
9669905 gain_of_function of juxtamembrane domain KIT mutants [plasma membrane]
9669889 gain_of_function of kinase domain KIT mutants [plasma membrane]
9673666 gain_of_function of membrane-tethered PDGFR fusion dimers [plasma membrane]
9673675 gain_of_function of membrane-tethered PDGFR fusions [plasma membrane]
6802888 gain_of_function of moderate kinase activity BRAF mutants [cytosol]
9660501 gain_of_function of mutant MRAS:SHOC2:PP1 complexes [plasma membrane]
6802891 gain_of_function of mutant RAS:GTP:p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6802893 gain_of_function of mutant RAS:GTP:p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
6803231 gain_of_function of mutant RAS:GTP:p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane]
6802894 gain_of_function of mutant RAS:inactive BRAF:RAF1 [plasma membrane]
6802897 gain_of_function of mutant RAS:inactive BRAF:p-S338,T491,S494,S729 RAF1 [plasma membrane]
9672144 gain_of_function of p-11Y PDGFR mutant dimers:PI3K [plasma membrane]
9672149 gain_of_function of p-11Y PDGFR mutant receptor dimers [plasma membrane]
9672150 gain_of_function of p-11Y PDGFR mutant receptor dimers [plasma membrane]
9672151 gain_of_function of p-11Y PDGFR mutant receptor dimers [plasma membrane]
9672146 gain_of_function of p-11Y PDGFR mutatnt receptors:GRB2:SOS1 [plasma membrane]
9672152 gain_of_function of p-11Y PDGFRA extracellular domain dimers [endoplasmic reticulum membrane]
9672148 gain_of_function of p-11Y PDGFRA extracellular domain dimers [endoplasmic reticulum membrane]
9672153 gain_of_function of p-11Y PDGFRA extracellular domain dimers:GRB2:SOS1 [endoplasmic reticulum membrane]
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