Identifier | Name |
---|---|
9643898 | lactose synthase activity of B4GALT1:LALBA [Golgi membrane] Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I |
9644067 | lipoprotein lipase activity of LIPG dimer [extracellular region] Identification of the active form of endothelial lipase, a homodimer in a head-to-tail conformation |
9643294 | long-chain fatty acid transporter activity of ABCD1 [peroxisomal membrane] Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis |
9643588 | long-chain fatty acid-CoA ligase activity of ACSL3,4 [endoplasmic reticulum membrane] A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients |
9643801 | long-chain-alcohol O-fatty-acyltransferase activity of AWAT1 [endoplasmic reticulum membrane] Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily |
9643153 | long-chain-alcohol O-fatty-acyltransferase activity of AWAT2 [endoplasmic reticulum membrane] Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family |
9835519 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor of ATAT [cytosol] Atomic resolution structure of human α-tubulin acetyltransferase bound to acetyl-CoA |
9643207 | lysophospholipase activity of Gdpd1 [endoplasmic reticulum membrane] New members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activity |
9643120 | lysophospholipase activity of Gdpd3 [endoplasmic reticulum membrane] New members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activity |
9643669 | lysophospholipase activity of PNPLA6 [endoplasmic reticulum membrane] Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells |
9643675 | lysophospholipase activity of Pnpla7 [endoplasmic reticulum membrane] Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase |
9643886 | mRNA (N6-adenosine)-methyltransferase activity of mRNA (N6-adenosine)-methyltransferase [nucleoplasm] A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation |
9861288 | mRNA regulatory element binding translation repressor activity of ACO1, IREB2 [cytosol] A regulated RNA binding protein also possesses aconitase activity |
9643758 | maleylacetoacetate isomerase activity of GSTZ1 dimer [cytosol] Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity |
9643314 | mannosyltransferase activity of PIGZ [endoplasmic reticulum membrane] Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo |
9643196 | membrane insertase activity of TIM23 SORT:Cargo [mitochondrial inner membrane] Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria |
9644127 | metallocarboxypeptidase activity of ACE2(18-805):Zn2+ dimer [plasma membrane] A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 |
9643371 | metallocarboxypeptidase activity of CPB1,2,3:Zn2+ [extracellular region] Human mast cell carboxypeptidase. Purification and characterization |
9643640 | metallocarboxypeptidase activity of Cpe:Zn2+ [secretory granule membrane] The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing |
9644055 | metallocarboxypeptidase activity of TTCP [cytosol] Tubulinyl-tyrosine carboxypeptidase from chicken brain: properties and partial purification |
9643114 | metallodipeptidase activity of ACE(30-1232):Zn2+ [extracellular region] Angiotensin I-converting enzyme mutation (Trp1197Stop) causes a dramatic increase in blood ACE |
9644105 | metallodipeptidase activity of ACE(30-1306):Zn2+ [plasma membrane] Catalysis of angiotensin I hydrolysis by human angiotensin-converting enzyme: effect of chloride and pH |
9643229 | metalloendopeptidase activity of BoNT/A LC:Zn2+ [cytosol] Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25 |
9643194 | metalloendopeptidase activity of BoNT/B LC:Zn2+ [cytosol] Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin |
9643247 | metalloendopeptidase activity of BoNT/C LC:Zn2+ [cytosol] Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release |
9644080 | metalloendopeptidase activity of BoNT/D LC:Zn2+ [cytosol] Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin |
9643983 | metalloendopeptidase activity of BoNT/E LC:Zn2+ [cytosol] Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds |
9643353 | metalloendopeptidase activity of BoNT/F LC:Zn2+ [cytosol] Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin |
9643381 | metalloendopeptidase activity of BoNT/G LC:Zn2+ [cytosol] Botulinum G neurotoxin cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond |
9643810 | metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria |
9643102 | metalloendopeptidase activity of MBTPS2 [Golgi membrane] ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs |
9643274 | metalloendopeptidase activity of MMP19 [extracellular region] Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme |
9643787 | metalloendopeptidase activity of PAPPA,PAPPA2 [extracellular region] Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin |
9643917 | metalloendopeptidase activity of STOML2:PARL:YME1L [mitochondrial inner membrane] The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria |
9643991 | metalloendopeptidase activity of TeNT LC:Zn2+ [cytosol] Cleavage of members of the synaptobrevin/VAMP family by types D and F botulinal neurotoxins and tetanus toxin |
9844183 | metalloendopeptidase activity of glc-fuc-ADAMTS13 [extracellular region] ADAMTS-13 cleaves long von Willebrand factor multimeric strings anchored to endothelial cells in the absence of flow, platelets or conformation-altering chemicals |
9643242 | metallopeptidase activity of ANPEP [plasma membrane] Metabolism of vasoactive peptides by plasma and purified renal aminopeptidase M |
9643119 | metallopeptidase activity of ANPEP:Zn2+ dimer [plasma membrane] Purification and characterization of aminopeptidase N from human plasma |
9643724 | metallopeptidase activity of ENPEP Dimer [plasma membrane] Enzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IV |
9643065 | metallopeptidase activity of LF [cytosol] Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity |
9643406 | metallopeptidase activity of MME:Zn2+ [plasma membrane] Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism |
9643217 | metallopeptidase activity of PITRM1 [mitochondrial matrix] Defective PITRM1 mitochondrial peptidase is associated with Aβ amyloidotic neurodegeneration |
9643717 | methylcrotonoyl-CoA carboxylase activity of 6x(Btn-MCCC1:MCCC2) [mitochondrial matrix] The molecular basis of human 3-methylcrotonyl-CoA carboxylase deficiency |
9643713 | methylglutaconyl-CoA hydratase activity of AUH hexamer [mitochondrial matrix] 3-Methylglutaconic aciduria type I is caused by mutations in AUH. |
9643277 | microfilament motor activity of GGC-Rala:GTP:Myo1c:Calm1:F-actin [cytoplasmic vesicle membrane] CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes |
9643267 | microtubule binding activity of HCMV Tegumented Virion [viral tegument] Tegument proteins of human cytomegalovirus |
9643604 | misfolded protein binding activity of HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates |
9763694 | molecular sequestering activity of TCN1 [extracellular region] Structural basis of transcobalamin recognition by human CD320 receptor |
9643654 | motor activity of Myosin-X dimer [cytosol] Myosin X is a downstream effector of PI(3)K during phagocytosis |
9643052 | nicotinate transmembrane transporter activity of SLC22A13 [plasma membrane] Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13) |
9643710 | nicotinate-nucleotide adenylyltransferase activity of NMNAT2:Mg2+ [Golgi membrane] Identification of a novel human nicotinamide mononucleotide adenylyltransferase |
9643341 | nucleoside diphosphate kinase activity of NME1,2 hexamers [cytosol] Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme |
9643657 | nucleoside diphosphate kinase activity of NME4 hexamer [mitochondrial inner membrane] The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase |
9643257 | nucleoside diphosphate kinase activity of Pck1 [cytosol] Phosphorylation of carbovir enantiomers by cellular enzymes determines the stereoselectivity of antiviral activity |
9643929 | nucleoside kinase activity of AK5,7,8,9 [cytosol] Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein |
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