Identifier | Name |
---|---|
9644018 | SUMO transferase activity of PIAS2-2 [nucleoplasm] The polycomb repressive complex 2 is a potential target of SUMO modifications |
9643863 | SUMO transferase activity of PIAS2-2,PIAS3,PIAS4 [nucleoplasm] SUMOylation of RORalpha potentiates transcriptional activation function |
9643302 | SUMO transferase activity of PIAS3 [nucleoplasm] Sumoylation of MITF and its related family members TFE3 and TFEB |
9643693 | SUMO transferase activity of PIAS4 [nucleoplasm] PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies |
9643250 | SUMO transferase activity of PML,TRIM27,PIAS1,2-1 [nucleoplasm] SUMO E3 ligase activity of TRIM proteins |
9644136 | SUMO transferase activity of PRC1 complex [nucleoplasm] The polycomb protein Pc2 is a SUMO E3 |
9643645 | SUMO transferase activity of Pias1 [nucleoplasm] Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation |
9643475 | SUMO transferase activity of Pias1,2-2 [nucleoplasm] Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification |
9643420 | SUMO transferase activity of RANBP2:RANGAP1-SUMO1:UBE2I:Nuclear Pore Complex (NPC) [nuclear envelope] The RanBP2/RanGAP1*SUMO1/Ubc9 complex is a multisubunit SUMO E3 ligase |
9643821 | SUMO transferase activity of Ranbp2 [nuclear envelope] Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha |
9644110 | SUMO transferase activity of SMC5-SMC6 Complex [nucleoplasm] Human MMS21/NSE2 is a SUMO ligase required for DNA repair |
9643746 | SUMO transferase activity of SUMO1:C93-UBE2I [cytosol] SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processing |
9644118 | SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm] Identification of a substrate recognition site on Ubc9 |
9643442 | SUMO transferase activity of TOPORS [nucleoplasm] TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins |
9643106 | SUMO transferase activity of TRIM28 [nucleoplasm] Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain |
9643195 | SUMO transferase activity of UBE2I,PIAS1 [nucleoplasm] Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene |
9643150 | SUMO transferase activity of ZBED1 [nucleoplasm] Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α |
9643544 | SUMO transferase activity of p14-ARF [nucleoplasm] p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase |
9643980 | SUMO transferase activity of p14-ARF:MDM2 [nucleoplasm] MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity |
9644146 | SUMO-specific endopeptidase activity of SENP1,2,5 [nucleoplasm] Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3 |
9725587 | TP63 [nucleoplasm] Enrichment and identification of human 'fetal' epidermal stem cells |
9643941 | UDP-glucose 4-epimerase activity of GALE:NAD+ dimer [cytosol] Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase |
9643662 | UDP-glucose:hexose-1-phosphate uridylyltransferase activity of GALT [cytosol] Molecular characterization of two galactosemia mutations: correlation of mutations with highly conserved domains in galactose-1-phosphate uridyl transferase |
9643272 | UTP:glucose-1-phosphate uridylyltransferase activity of 8xUGP2 [cytosol] Uridine diphosphate glucose pyrophosphorylase. IV. Crystallization and properties of the enzyme from human liver |
9643618 | XTP diphosphatase activity of ITPA dimer [cytosol] Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene |
9839464 | YAP1 [nucleoplasm] Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin |
9644040 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity of PDP [mitochondrial matrix] Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation |
9644028 | acetate CoA-transferase activity of ACAA1 [peroxisomal matrix] Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid |
9643691 | acetate-CoA ligase activity of ACSS1 [mitochondrial matrix] Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 |
9643975 | acetyl-CoA C-acetyltransferase activity of ACAT1 tetramer [mitochondrial matrix] Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function |
9644008 | acetyl-CoA:L-glutamate N-acetyltransferase activity of NAGS(19-534) [mitochondrial matrix] Cloning and expression of the human N-acetylglutamate synthase gene |
9644079 | acetyltransferase activity of BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] BRD7 is a candidate tumour suppressor gene required for p53 function |
9643674 | acetyltransferase activity of Kat2b [nucleoplasm] Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
9643066 | acetyltransferase activity of NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB |
9815401 | acidic amino acid transmembrane transporter activity of SLC25A12,13 [mitochondrial inner membrane] Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria |
9643553 | aconitate hydratase activity of ACO2:4Fe-4S [mitochondrial matrix] Aconitase polymorphism in man |
9643149 | acyl carnitine transmembrane transporter activity of SLC25A20 [mitochondrial inner membrane] Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient |
9643220 | acyl-CoA dehydrogenase activity of ACAD8 tetramer [mitochondrial matrix] Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans |
9643583 | acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix] Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism |
9643238 | acyl-[acyl-carrier-protein] hydrolase activity of Olah [cytosol] Purification and properties of a thioesterase from lactating rat mammary gland which modifies the product specificity of fatty acid synthetase |
9837328 | acyl-coenzyme A diphosphatase activity of Nudt8 [mitochondrial matrix] Nudt8 is a novel CoA diphosphohydrolase that resides in the mitochondria |
9734726 | adenine phosphoribosyltransferase activity of APRT dimer [cytosol] Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism |
9734192 | adenine phosphoribosyltransferase activity of APRT dimer mutants [cytosol] Adenine phosphoribosyltransferase deficiency |
9643275 | adenosine kinase activity of ADK [cytosol] Purification and properties of human placental adenosine kinase |
9643342 | adenylate cyclase activity of cya [cytosol] Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells |
9860673 | adenylate cyclase inhibitor activity of G-beta:G-gamma (candidates) [plasma membrane] Inhibition of adenylyl cyclase isoforms V and VI by various Gbetagamma subunits |
9643852 | adenylate kinase activity of AK2 [mitochondrial intermembrane space] Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne muscular dystrophic serum aberrant adenylate kinase |
9643410 | adenylate kinase activity of Adenylate Kinase [cytosol] AMP (dAMP) kinase from human erythrocytes |
9643738 | adenylosuccinate synthase activity of ADSS, ADSSL1 dimers [cytosol] Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells |
9643878 | alcohol dehydrogenase activity, zinc-dependent of alcohol dehydrogenase complex [cytosol] Human liver alcohol dehydrogenase: purification, composition, and catalytic features |
9643060 | aldehyde dehydrogenase (NAD) activity of ADH1L2 tetramer [mitochondrial matrix] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase |
9643616 | aldehyde dehydrogenase (NAD) activity of ALDH1A1 tetramer [cytosol] Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes |
9643127 | aldehyde dehydrogenase (NAD) activity of ALDH1L1 tetramer [cytosol] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase |
9644480 | aldehyde dehydrogenase (NAD) activity of ALDH2 tetramer [mitochondrial matrix] Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations. |
9643465 | aldehyde dehydrogenase (NAD) activity of ALDH3A2-1 dimer [endoplasmic reticulum membrane] Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization |
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