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Entries: ControlReference
Identifier Name
9643416 GTPase activity of GGC-Rala:GTP [cytoplasmic vesicle membrane] A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
9643900 GTPase activity of RAB33:GTP [Golgi membrane] OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation
9643725 GTPase activity of RAB35:GTP [clathrin-coated endocytic vesicle membrane] Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis
9643259 GTPase activity of RAB7A:GTP [lysosomal membrane] The rab7 GTPase resides on a vesicular compartment connected to lysosomes
9643804 GTPase activity of p-Y1105-ARHGAP35:RHOA:GTP [cytosol] Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion
9820691 HC-ABCG2 [plasma membrane] Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis
9728013 HOPX [nucleoplasm] Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes
9643590 IDP phosphatase activity of NUDT16 dimer [nucleoplasm] NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest
9643517 IMP dehydrogenase activity of IMPDH tetramers [cytosol] Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding
9643305 ISG15-specific peptidase activity of USP18 [cytosol] UBP43 (USP18) specifically removes ISG15 from conjugated proteins
9731954 ITGA6(24-1130) [plasma membrane] Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype
9725614 ITGB1 [plasma membrane] Enrichment and identification of human 'fetal' epidermal stem cells
9731950 ITGB4 [plasma membrane] Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
9643791 ITP diphosphatase activity of ITPA dimer [cytosol] Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene
9728022 KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
9728087 KLK5 [cytosol] Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum
9728084 KLK7 [cytosol] Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation
9728025 KLK7 [cytosol] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum
9727377 KRT1 [cytosol] Epidermal differentiation: the bare essentials
9727378 KRT10 [cytosol] Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis
9725565 KRT19 [cytosol] The type I keratin 19 possesses distinct and context-dependent assembly properties
9727409 KRT24 [cytosol] Role of keratin 24 in human epidermal keratinocytes
9725597 KRT78 [cytosol] Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression
9643950 L-alanine:2-oxoglutarate aminotransferase activity of GPT dimer [cytosol] cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase
9643767 L-alanine:2-oxoglutarate aminotransferase activity of GPT2 dimer [mitochondrial matrix] cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase
9643913 L-amino-acid oxidase activity of IL4I1:FAD [extracellular region] Human IL4I1 is a secreted L-phenylalanine oxidase expressed by mature dendritic cells that inhibits T-lymphocyte proliferation
9643397 L-aminoadipate-semialdehyde dehydrogenase activity of ALDH7A1 tetramer [mitochondrial matrix] Mutations in antiquitin in individuals with pyridoxine-dependent seizures
9643893 L-aspartate:2-oxoglutarate aminotransferase activity of GOT2 dimer [mitochondrial matrix] Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy
9643270 L-glucuronate reductase activity of AKR1A1 [cytosol] Mechanism of human aldehyde reductase: characterization of the active site pocket
9643934 L-glutamine:pyruvate aminotransferase activity of PXLP-KYAT1 dimer [cytosol] Purification and characterization of kynurenine aminotransferase I from human brain
9643799 L-gulonate 3-dehydrogenase activity of CRYL1 dimer [cytosol] Structural and functional characterization of rabbit and human L-gulonate 3-dehydrogenase
9643825 L-iditol 2-dehydrogenase activity of SORD tetramer [cytosol] Polyol-pathway enzymes of human brain. Partial purification and properties of sorbitol dehydrogenase
9643670 L-lactate dehydrogenase activity of LDH tetramer [cytosol] Properties of human testis-specific lactate dehydrogenase expressed from Escherichia coli
9815320 L-malate dehydrogenase activity of MDH1 dimer [cytosol] Biochemical and genetic identity of alpha-keto acid reductase and cytoplasmic malate dehydrogenase from human erythrocytes
9643763 L-malate dehydrogenase activity of MDH2 dimer [mitochondrial matrix] An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates
9643582 L-ornithine transmembrane transporter activity of Mitochondrial ornithine transporters [mitochondrial inner membrane] The mitochondrial ornithine transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution of two human isoforms
9643905 L-phenylalanine:pyruvate aminotransferase activity of PXLP-KYAT1 dimer [cytosol] Purification and characterization of kynurenine aminotransferase I from human brain
9643585 L-proline transmembrane transporter activity of SLC36A4 [plasma membrane] SLC36A4 (hPAT4) is a high affinity amino acid transporter when expressed in Xenopus laevis oocytes
9643289 L-tryptophan transmembrane transporter activity of SLC36A4 [plasma membrane] SLC36A4 (hPAT4) is a high affinity amino acid transporter when expressed in Xenopus laevis oocytes
9643179 L-xylulose reductase (NADP+) activity of DCXR tetramer [plasma membrane] Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney
9861125 LGALS7 [cytosol] Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid
9731159 LRIG1 [plasma membrane] Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
9731943 LRIG1 mRNA [cytosol] Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
9861247 LY6D mRNA [cytosol] Transcriptional profiling of epidermal keratinocytes: comparison of genes expressed in skin, cultured keratinocytes, and reconstituted epidermis, using large DNA microarrays
9711059 Lys48-specific deubiquitinase activity of RTC [double membrane vesicle viral factory outer membrane] Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease
9711003 Lys63-specific deubiquitinase activity of N-glycan pp1a-nsp3 [endoplasmic reticulum membrane] SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex
9643737 Lys63-specific deubiquitinase activity of OTUD5 [cytosol] DUBA: a deubiquitinase that regulates type I interferon production
9685212 Lys63-specific deubiquitinase activity of RTC [double membrane vesicle viral factory outer membrane] SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6
9818966 Lys63-specific deubiquitinase activity of TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling
9643552 Lys63-specific deubiquitinase activity of TNFAIP3 [cytosol] Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity
9750947 Lys63-specific deubiquitinase activity of USP14 [cytosol] Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch
9643366 MAP kinase kinase activity of Mekk1 [cytosol] Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain
9643515 MAP kinase kinase kinase activity of MAP3K1 [cytosol] Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain
9644066 MAP kinase kinase kinase activity of TAK1 complex [cytosol] TAK1 is a ubiquitin-dependent kinase of MKK and IKK
9643180 MAP kinase kinase kinase activity of Tpl2 [cytosol] Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase
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