Identifier | Name |
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9644146 | SUMO-specific endopeptidase activity of SENP1,2,5 [nucleoplasm] Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3 |
9643941 | UDP-glucose 4-epimerase activity of GALE:NAD+ dimer [cytosol] Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase |
9643662 | UDP-glucose:hexose-1-phosphate uridylyltransferase activity of GALT [cytosol] Molecular characterization of two galactosemia mutations: correlation of mutations with highly conserved domains in galactose-1-phosphate uridyl transferase |
9643272 | UTP:glucose-1-phosphate uridylyltransferase activity of 8xUGP2 [cytosol] Uridine diphosphate glucose pyrophosphorylase. IV. Crystallization and properties of the enzyme from human liver |
9643618 | XTP diphosphatase activity of ITPA dimer [cytosol] Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene |
9644040 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity of PDP [mitochondrial matrix] Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation |
9644028 | acetate CoA-transferase activity of ACAA1 [peroxisomal matrix] Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid |
9643691 | acetate-CoA ligase activity of ACSS1 [mitochondrial matrix] Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 |
9643975 | acetyl-CoA C-acetyltransferase activity of ACAT1 tetramer [mitochondrial matrix] Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function |
9644008 | acetyl-CoA:L-glutamate N-acetyltransferase activity of NAGS(19-534) [mitochondrial matrix] Cloning and expression of the human N-acetylglutamate synthase gene |
9644079 | acetyltransferase activity of BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] BRD7 is a candidate tumour suppressor gene required for p53 function |
9643674 | acetyltransferase activity of Kat2b [nucleoplasm] Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription. |
9643066 | acetyltransferase activity of NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB |
9815401 | acidic amino acid transmembrane transporter activity of SLC25A12,13 [mitochondrial inner membrane] Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria |
9643553 | aconitate hydratase activity of ACO2:4Fe-4S [mitochondrial matrix] Aconitase polymorphism in man |
9643149 | acyl carnitine transmembrane transporter activity of SLC25A20 [mitochondrial inner membrane] Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient |
9643220 | acyl-CoA dehydrogenase activity of ACAD8 tetramer [mitochondrial matrix] Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans |
9643583 | acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix] Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism |
9643238 | acyl-[acyl-carrier-protein] hydrolase activity of Olah [cytosol] Purification and properties of a thioesterase from lactating rat mammary gland which modifies the product specificity of fatty acid synthetase |
9837328 | acyl-coenzyme A diphosphatase activity of Nudt8 [mitochondrial matrix] Nudt8 is a novel CoA diphosphohydrolase that resides in the mitochondria |
9734726 | adenine phosphoribosyltransferase activity of APRT dimer [cytosol] Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism |
9734192 | adenine phosphoribosyltransferase activity of APRT dimer mutants [cytosol] Adenine phosphoribosyltransferase deficiency |
9643275 | adenosine kinase activity of ADK [cytosol] Purification and properties of human placental adenosine kinase |
9643342 | adenylate cyclase activity of cya [cytosol] Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells |
9860673 | adenylate cyclase inhibitor activity of G-beta:G-gamma (candidates) [plasma membrane] Inhibition of adenylyl cyclase isoforms V and VI by various Gbetagamma subunits |
9643852 | adenylate kinase activity of AK2 [mitochondrial intermembrane space] Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne muscular dystrophic serum aberrant adenylate kinase |
9643410 | adenylate kinase activity of Adenylate Kinase [cytosol] AMP (dAMP) kinase from human erythrocytes |
9643738 | adenylosuccinate synthase activity of ADSS, ADSSL1 dimers [cytosol] Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells |
9643878 | alcohol dehydrogenase activity, zinc-dependent of alcohol dehydrogenase complex [cytosol] Human liver alcohol dehydrogenase: purification, composition, and catalytic features |
9643060 | aldehyde dehydrogenase (NAD) activity of ADH1L2 tetramer [mitochondrial matrix] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase |
9643616 | aldehyde dehydrogenase (NAD) activity of ALDH1A1 tetramer [cytosol] Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes |
9643127 | aldehyde dehydrogenase (NAD) activity of ALDH1L1 tetramer [cytosol] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase |
9644480 | aldehyde dehydrogenase (NAD) activity of ALDH2 tetramer [mitochondrial matrix] Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations. |
9643465 | aldehyde dehydrogenase (NAD) activity of ALDH3A2-1 dimer [endoplasmic reticulum membrane] Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization |
9643869 | aldehyde dehydrogenase [NAD(P)+] activity of ALDH3B2 [lipid droplet] Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification |
9643735 | aldehyde-lyase activity of SHMT1 tetramer [cytosol] Affinity purification and characterization of serine hydroxymethyltransferases from rat liver |
9644770 | alditol:NADP+ 1-oxidoreductase activity of AKR1B1 [cytosol] Aldose reductase is a major reductase for isocaproaldehyde, a product of side-chain cleavage of cholesterol, in human and animal adrenal glands |
9644772 | alditol:NADP+ 1-oxidoreductase activity of AKR1B1 [cytosol] Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysts |
9643760 | alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane] Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains |
9643896 | alpha-glucosidase activity of GAA (70, 76 kDa) [lysosomal lumen] Simultaneous absence of alpha-1,4-glucosidase and alpha-1,6-glucosidase activities (pH 4) in tissues of children with type II glycogen storage disease |
9860675 | alpha2-adrenergic receptor activity of ADRA2A,C [plasma membrane] An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling |
9643532 | amino acid transmembrane transporter activity of SLC7A8:SLC3A2 heterodimer [plasma membrane] Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids |
9643319 | aminopeptidase activity of IFN gamma stimulated aminopeptidases [cytosol] Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase |
9643828 | aminopeptidase activity of IRAP in complex with MHC class I [early endosome membrane] Different cross-presentation pathways in steady-state and inflammatory dendritic cells |
9644006 | amylo-alpha-1,6-glucosidase activity of AGL [cytosol] Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease. |
9643091 | anion channel activity of AQP6 tetramer [transport vesicle membrane] cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13 |
9643696 | arginase activity of ARG1 trimer [cytosol] Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response |
9643729 | arginase activity of ARG2 trimer [mitochondrial matrix] Human arginase II: crystal structure and physiological role in male and female sexual arousal |
9643560 | argininosuccinate lyase activity of ASL tetramer [cytosol] Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region |
9643595 | argininosuccinate synthase activity of ASS1 tetramer:NMRAL1 dimer:NADPH [cytosol] Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene |
9643819 | asparagine synthase (glutamine-hydrolyzing) activity of ASNS dimer [cytosol] Expression of human asparagine synthetase in Escherichia coli |
9643589 | aspartic-type endopeptidase activity of Caspase-3 [cytosol] The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis |
9643694 | aspartic-type endopeptidase activity of Prorenin-Prorenin Receptor [plasma membrane] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin |
9643775 | aspartic-type endopeptidase activity of Renin [extracellular region] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin |
9643424 | aspartic-type endopeptidase activity of Renin:Prorenin Receptor [plasma membrane] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin |
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