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Entries: CatalystActivityReference
Identifier Name
9644146 SUMO-specific endopeptidase activity of SENP1,2,5 [nucleoplasm] Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3
9643941 UDP-glucose 4-epimerase activity of GALE:NAD+ dimer [cytosol] Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase
9643662 UDP-glucose:hexose-1-phosphate uridylyltransferase activity of GALT [cytosol] Molecular characterization of two galactosemia mutations: correlation of mutations with highly conserved domains in galactose-1-phosphate uridyl transferase
9643272 UTP:glucose-1-phosphate uridylyltransferase activity of 8xUGP2 [cytosol] Uridine diphosphate glucose pyrophosphorylase. IV. Crystallization and properties of the enzyme from human liver
9643618 XTP diphosphatase activity of ITPA dimer [cytosol] Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene
9644040 [pyruvate dehydrogenase (lipoamide)] phosphatase activity of PDP [mitochondrial matrix] Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation
9644028 acetate CoA-transferase activity of ACAA1 [peroxisomal matrix] Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid
9643691 acetate-CoA ligase activity of ACSS1 [mitochondrial matrix] Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
9643975 acetyl-CoA C-acetyltransferase activity of ACAT1 tetramer [mitochondrial matrix] Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function
9644008 acetyl-CoA:L-glutamate N-acetyltransferase activity of NAGS(19-534) [mitochondrial matrix] Cloning and expression of the human N-acetylglutamate synthase gene
9644079 acetyltransferase activity of BRD7:p-S15,S20-TP53:EP300 [nucleoplasm] BRD7 is a candidate tumour suppressor gene required for p53 function
9643674 acetyltransferase activity of Kat2b [nucleoplasm] Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription.
9643066 acetyltransferase activity of NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
9815401 acidic amino acid transmembrane transporter activity of SLC25A12,13 [mitochondrial inner membrane] Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria
9643553 aconitate hydratase activity of ACO2:4Fe-4S [mitochondrial matrix] Aconitase polymorphism in man
9643149 acyl carnitine transmembrane transporter activity of SLC25A20 [mitochondrial inner membrane] Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient
9643220 acyl-CoA dehydrogenase activity of ACAD8 tetramer [mitochondrial matrix] Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans
9643583 acyl-CoA dehydrogenase activity of ACADSB tetramer [mitochondrial matrix] Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism
9643238 acyl-[acyl-carrier-protein] hydrolase activity of Olah [cytosol] Purification and properties of a thioesterase from lactating rat mammary gland which modifies the product specificity of fatty acid synthetase
9837328 acyl-coenzyme A diphosphatase activity of Nudt8 [mitochondrial matrix] Nudt8 is a novel CoA diphosphohydrolase that resides in the mitochondria
9734726 adenine phosphoribosyltransferase activity of APRT dimer [cytosol] Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism
9734192 adenine phosphoribosyltransferase activity of APRT dimer mutants [cytosol] Adenine phosphoribosyltransferase deficiency
9643275 adenosine kinase activity of ADK [cytosol] Purification and properties of human placental adenosine kinase
9643342 adenylate cyclase activity of cya [cytosol] Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells
9860673 adenylate cyclase inhibitor activity of G-beta:G-gamma (candidates) [plasma membrane] Inhibition of adenylyl cyclase isoforms V and VI by various Gbetagamma subunits
9643852 adenylate kinase activity of AK2 [mitochondrial intermembrane space] Adenosine triphosphate-adenosine-5'-monophosphate phosphotransferase from normal human liver mitochondria. Isolation, chemical properties, and immunochemical comparison with Duchenne muscular dystrophic serum aberrant adenylate kinase
9643410 adenylate kinase activity of Adenylate Kinase [cytosol] AMP (dAMP) kinase from human erythrocytes
9643738 adenylosuccinate synthase activity of ADSS, ADSSL1 dimers [cytosol] Molecular cloning and characterization of a novel muscle adenylosuccinate synthetase, AdSSL1, from human bone marrow stromal cells
9643878 alcohol dehydrogenase activity, zinc-dependent of alcohol dehydrogenase complex [cytosol] Human liver alcohol dehydrogenase: purification, composition, and catalytic features
9643060 aldehyde dehydrogenase (NAD) activity of ADH1L2 tetramer [mitochondrial matrix] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase
9643616 aldehyde dehydrogenase (NAD) activity of ALDH1A1 tetramer [cytosol] Purification and partial characterization of aldehyde dehydrogenase from human erythrocytes
9643127 aldehyde dehydrogenase (NAD) activity of ALDH1L1 tetramer [cytosol] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase
9644480 aldehyde dehydrogenase (NAD) activity of ALDH2 tetramer [mitochondrial matrix] Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations.
9643465 aldehyde dehydrogenase (NAD) activity of ALDH3A2-1 dimer [endoplasmic reticulum membrane] Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization
9643869 aldehyde dehydrogenase [NAD(P)+] activity of ALDH3B2 [lipid droplet] Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification
9643735 aldehyde-lyase activity of SHMT1 tetramer [cytosol] Affinity purification and characterization of serine hydroxymethyltransferases from rat liver
9644770 alditol:NADP+ 1-oxidoreductase activity of AKR1B1 [cytosol] Aldose reductase is a major reductase for isocaproaldehyde, a product of side-chain cleavage of cholesterol, in human and animal adrenal glands
9644772 alditol:NADP+ 1-oxidoreductase activity of AKR1B1 [cytosol] Aldose reductase: model for a new paradigm of enzymic perfection in detoxification catalysts
9643760 alpha-1,4-glucosidase activity of sucrase-isomaltase dimer [plasma membrane] Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains
9643896 alpha-glucosidase activity of GAA (70, 76 kDa) [lysosomal lumen] Simultaneous absence of alpha-1,4-glucosidase and alpha-1,6-glucosidase activities (pH 4) in tissues of children with type II glycogen storage disease
9860675 alpha2-adrenergic receptor activity of ADRA2A,C [plasma membrane] An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling
9643532 amino acid transmembrane transporter activity of SLC7A8:SLC3A2 heterodimer [plasma membrane] Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids
9643319 aminopeptidase activity of IFN gamma stimulated aminopeptidases [cytosol] Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase
9643828 aminopeptidase activity of IRAP in complex with MHC class I [early endosome membrane] Different cross-presentation pathways in steady-state and inflammatory dendritic cells
9644006 amylo-alpha-1,6-glucosidase activity of AGL [cytosol] Glycogen debranching enzyme: purification, antibody characterization, and immunoblot analyses of type III glycogen storage disease.
9643091 anion channel activity of AQP6 tetramer [transport vesicle membrane] cDNA cloning and gene structure of a novel water channel expressed exclusively in human kidney: evidence for a gene cluster of aquaporins at chromosome locus 12q13
9643696 arginase activity of ARG1 trimer [cytosol] Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response
9643729 arginase activity of ARG2 trimer [mitochondrial matrix] Human arginase II: crystal structure and physiological role in male and female sexual arousal
9643560 argininosuccinate lyase activity of ASL tetramer [cytosol] Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region
9643595 argininosuccinate synthase activity of ASS1 tetramer:NMRAL1 dimer:NADPH [cytosol] Mutations and polymorphisms in the human argininosuccinate synthetase (ASS1) gene
9643819 asparagine synthase (glutamine-hydrolyzing) activity of ASNS dimer [cytosol] Expression of human asparagine synthetase in Escherichia coli
9643589 aspartic-type endopeptidase activity of Caspase-3 [cytosol] The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis
9643694 aspartic-type endopeptidase activity of Prorenin-Prorenin Receptor [plasma membrane] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
9643775 aspartic-type endopeptidase activity of Renin [extracellular region] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
9643424 aspartic-type endopeptidase activity of Renin:Prorenin Receptor [plasma membrane] Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
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