Reactome | RAB8 GEFs exchange GTP for GDP on RAB8

Schema > Reaction > Entries

RAB8 GEFs exchange GTP for GDP on RAB8 Show undefined attributes

catalystActivity	[CatalystActivity:10546813] guanyl-nucleotide exchange factor activity of RAB8 GEFs [cytosol]
category	transition
compartment	[Compartment:263163] trans-Golgi network membrane [Compartment:70101] cytosol
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10546815
displayName	RAB8 GEFs exchange GTP for GDP on RAB8
eventOf	[Pathway:R-XTR-8876198] RAB GEFs exchange GTP for GDP on RABs - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8876190] RAB8 GEFs exchange GTP for GDP on RAB8 - Homo sapiens
input	[Complex:R-XTR-8876120] GGC-RAB8:GDP:GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
name	RAB8 GEFs exchange GTP for GDP on RAB8
output	[DefinedSet:R-XTR-8875305] GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-XTR-8876116] GGC-RAB8:GTP [trans-Golgi network membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8876190
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-8876198] RAB GEFs exchange GTP for GDP on RABs
(inferredTo)	[Reaction:R-HSA-8876190] RAB8 GEFs exchange GTP for GDP on RAB8

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