Reactome | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Show undefined attributes

created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10559106
displayName	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
eventOf	[Pathway:R-XTR-212436] Generic Transcription Pathway - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81881] regulation of transcription by RNA polymerase II
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-XTR-8866907] Activation of the TFAP2 (AP-2) family of transcription factors - Xenopus tropicalis [Pathway:R-XTR-8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors - Xenopus tropicalis [Pathway:R-XTR-8869496] TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation - Xenopus tropicalis [Reaction:R-XTR-8869580] DEK binds TFAP2A homodimers - Xenopus tropicalis [Pathway:R-XTR-8866904] Negative regulation of activity of TFAP2 (AP-2) family transcription factors - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors - Homo sapiens
isInDisease	false
isInferred	true
name	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-8864260
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-212436] Generic Transcription Pathway
(inferredTo)	[Pathway:R-HSA-8864260] Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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