Reactome | D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+

Schema > Reaction > Entries

D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ Show undefined attributes

catalystActivity	[CatalystActivity:10489662] 3-hydroxybutyrate dehydrogenase activity of BDH1 tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10489668
displayName	D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+
eventOf	[Pathway:R-XTR-77108] Utilization of Ketone Bodies - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-73920] D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ - Homo sapiens
input	[SimpleEntity:R-ALL-73911] bHBA [mitochondrial matrix] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix]
isInDisease	false
isInferred	true
name	D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+
output	[SimpleEntity:R-ALL-73909] ACA [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-73920
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-77108] Utilization of Ketone Bodies
(precedingEvent)	[Reaction:R-XTR-74177] OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA
(inferredTo)	[Reaction:R-HSA-73920] D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+