Reactome | DNA polymerases delta, epsilon or kappa bind the TC-NER site

Schema > Reaction > Entries

DNA polymerases delta, epsilon or kappa bind the TC-NER site Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10537595
displayName	DNA polymerases delta, epsilon or kappa bind the TC-NER site
eventOf	[Pathway:R-XTR-6782135] Dual incision in TC-NER - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site - Homo sapiens
input	[DefinedSet:R-XTR-6790532] PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] [CandidateSet:R-XTR-5651800] POLD,POLE [nucleoplasm] [Complex:R-XTR-68436] RFC Heteropentamer [nucleoplasm] [Complex:R-XTR-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm]
isInDisease	false
isInferred	true
name	DNA polymerases delta, epsilon or kappa bind the TC-NER site
output	[Complex:R-XTR-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
precedingEvent	[Reaction:R-XTR-6782204] 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER - Xenopus tropicalis
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-6782211
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-6782135] Dual incision in TC-NER
(inferredTo)	[Reaction:R-HSA-6782211] DNA polymerases delta, epsilon or kappa bind the TC-NER site

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