Reactome | RAP1A exchanges GDP for GTP

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RAP1A exchanges GDP for GTP Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10504428
displayName	RAP1A exchanges GDP for GTP
eventOf	[Pathway:R-XTR-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-381727] RAP1A exchanges GDP for GTP - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-XTR-5252143] RAP1A:GDP [plasma membrane]
isInDisease	false
isInferred	true
name	RAP1A exchanges GDP for GTP
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-XTR-5252145] RAP1A:GTP [plasma membrane]
precedingEvent	[Reaction:R-XTR-381668] cAMP activates EPAC1 - Xenopus tropicalis [Reaction:R-XTR-381608] cAMP activates EPAC2 - Xenopus tropicalis
regulatedBy	[PositiveRegulation:10501585] Positive regulation by 'RAPGEF3:cAMP complex [plasma membrane]' [PositiveRegulation:10501584] Positive regulation by 'RAPGEF4:cAMP Complex [plasma membrane]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-381727
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
(inferredTo)	[Reaction:R-HSA-381727] RAP1A exchanges GDP for GTP