Reactome | ATP7A transports cytosolic Cu2+ to phagosomal lumen

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ATP7A transports cytosolic Cu2+ to phagosomal lumen Show undefined attributes

catalystActivity	[CatalystActivity:10401330] P-type divalent copper transporter activity of ATP7A:PDZD11 [phagocytic vesicle membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:1222282] phagocytic vesicle lumen [Compartment:1222693] phagocytic vesicle membrane
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10401332
displayName	ATP7A transports cytosolic Cu2+ to phagosomal lumen
eventOf	[Pathway:R-SSC-6803544] Ion influx/efflux at host-pathogen interface - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6803545] ATP7A transports cytosolic Cu2+ to phagosomal lumen - Homo sapiens
input	[Complex:R-SSC-3697875] ATOX1:Cu1+ [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	ATP7A transports cytosolic Cu2+ to phagosomal lumen Copper export from cells by copper-transporting ATPase1
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-SSC-3697884] ATOX1 [cytosol] [SimpleEntity:R-ALL-6803540] Cu1+ [phagocytic vesicle lumen] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-6803545
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-6803544] Ion influx/efflux at host-pathogen interface
(inferredTo)	[Reaction:R-HSA-6803545] ATP7A transports cytosolic Cu2+ to phagosomal lumen

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