Reactome | PARP1 or PARP2 PARylates DDB2 and autoPARylates

Schema > Reaction > Entries

PARP1 or PARP2 PARylates DDB2 and autoPARylates Show undefined attributes

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10394720
displayName	PARP1 or PARP2 PARylates DDB2 and autoPARylates
eventOf	[Pathway:R-SSC-5696394] DNA Damage Recognition in GG-NER - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-5691000] TFIIH binds GG-NER site to form a verification complex - Sus scrofa
inferredFrom	[Reaction:R-HSA-5696655] PARP1 or PARP2 PARylates DDB2 and autoPARylates - Homo sapiens
input	[SimpleEntity:R-ALL-427523] NAD+ [nucleoplasm] [Complex:R-SSC-5696660] Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm]
isInDisease	false
isInferred	true
name	PARP1 or PARP2 PARylates DDB2 and autoPARylates
output	[SimpleEntity:R-ALL-427497] NAM [nucleoplasm] [Complex:R-SSC-5696681] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:PAR-PARP1,PAR-PARP2 [nucleoplasm]
precedingEvent	[Reaction:R-SSC-5696664] PARP1 or PARP2 binds DDB2 at GG-NER site - Sus scrofa
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5696655
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5696394] DNA Damage Recognition in GG-NER
(precedingEvent)	[Reaction:R-SSC-5691000] TFIIH binds GG-NER site to form a verification complex
(inferredTo)	[Reaction:R-HSA-5696655] PARP1 or PARP2 PARylates DDB2 and autoPARylates