Reactome | Formation of MSH2:MSH3 Complex

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Formation of MSH2:MSH3 Complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10384900
displayName	Formation of MSH2:MSH3 Complex
eventOf	[Pathway:R-SSC-5358606] Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-SSC-5358513] MSH2:MSH3 binds insertion/deletion loop of 2 bases or more - Sus scrofa
inferredFrom	[Reaction:R-HSA-5444511] Formation of MSH2:MSH3 Complex - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5357525] MSH2 [nucleoplasm] [EntityWithAccessionedSequence:R-SSC-5357519] MSH3 [nucleoplasm]
isInDisease	false
isInferred	true
name	Formation of MSH2:MSH3 Complex
output	[Complex:R-SSC-5357508] MSH2:MSH3:ADP [nucleoplasm]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-5444511
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-5358606] Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
(precedingEvent)	[Reaction:R-SSC-5358513] MSH2:MSH3 binds insertion/deletion loop of 2 bases or more
(inferredTo)	[Reaction:R-HSA-5444511] Formation of MSH2:MSH3 Complex

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