Reactome | Thrombin binding to GP1b:IX:V

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10346773
displayName	Thrombin binding to GP1b:IX:V
eventOf	[Pathway:R-SSC-76009] Platelet Aggregation (Plug Formation) - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-429529] Thrombin binding to GP1b:IX:V - Homo sapiens
input	[Complex:R-SSC-156786] activated thrombin (factor IIa) [extracellular region] [Complex:R-SSC-435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane]
isInDisease	false
isInferred	true
name	Thrombin binding to GP1b:IX:V
output	[Complex:R-SSC-429532] GP1b-IX-V complex:activated thrombin (factor IIa) [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-429529
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-76009] Platelet Aggregation (Plug Formation)
(inferredTo)	[Reaction:R-HSA-429529] Thrombin binding to GP1b:IX:V