Reactome | p-TEFb phosphorylates serine 2 in RNA polymerase II CTD

Schema > Reaction > Entries

p-TEFb phosphorylates serine 2 in RNA polymerase II CTD Show undefined attributes

catalystActivity	[CatalystActivity:10896560] protein serine/threonine kinase activity of MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10896562
displayName	p-TEFb phosphorylates serine 2 in RNA polymerase II CTD
eventOf	[Pathway:R-SPO-9018519] Estrogen-dependent gene expression - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9012319] p-TEFb phosphorylates serine 2 in RNA polymerase II CTD - Homo sapiens
input	52 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-SPO-9012311] MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm]
isInDisease	false
isInferred	true
name	p-TEFb phosphorylates serine 2 in RNA polymerase II CTD
output	52 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-SPO-9012290] MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-9012319
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9018519] Estrogen-dependent gene expression
(inferredTo)	[Reaction:R-HSA-9012319] p-TEFb phosphorylates serine 2 in RNA polymerase II CTD

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