Reactome | RAB3 GEFs exchange GTP for GDP on RAB3A

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RAB3 GEFs exchange GTP for GDP on RAB3A Show undefined attributes

catalystActivity	[CatalystActivity:10895299] guanyl-nucleotide exchange factor activity of RAB3 GEFs [cytosol]
category	transition
compartment	[Compartment:216813] secretory granule membrane [Compartment:70101] cytosol
created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10895301
displayName	RAB3 GEFs exchange GTP for GDP on RAB3A
eventOf	[Pathway:R-SPO-8876198] RAB GEFs exchange GTP for GDP on RABs - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8875318] RAB3 GEFs exchange GTP for GDP on RAB3A - Homo sapiens
input	[Complex:R-SPO-8875313] GGC-RAB3A:GDP:GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
name	RAB3 GEFs exchange GTP for GDP on RAB3A
output	[DefinedSet:R-SPO-8875305] GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-SPO-8875326] GGC-RAB3A:GTP [secretory granule membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-8875318
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-8876198] RAB GEFs exchange GTP for GDP on RABs
(inferredTo)	[Reaction:R-HSA-8875318] RAB3 GEFs exchange GTP for GDP on RAB3A

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