Reactome | Formation of eIF2:GDP:eIF2B intermediate

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Formation of eIF2:GDP:eIF2B intermediate Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10873391
displayName	Formation of eIF2:GDP:eIF2B intermediate
eventOf	[Pathway:R-SPO-72731] Recycling of eIF2:GDP - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-72722] eIF2 activation - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-72670] Formation of eIF2:GDP:eIF2B intermediate - Homo sapiens
input	[Complex:R-SPO-72530] eIF2:GDP [cytosol] [Complex:R-SPO-72526] eIF2B subunits complex [cytosol]
isInDisease	false
isInferred	true
name	Formation of eIF2:GDP:eIF2B intermediate
output	[Complex:R-SPO-72529] eIF2:GDP: eIF2B [cytosol]
precedingEvent	[Reaction:R-SPO-72619] eIF2:GTP is hydrolyzed, eIFs are released - Schizosaccharomyces pombe
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-72670
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-72731] Recycling of eIF2:GDP
(precedingEvent)	[Reaction:R-SPO-72722] eIF2 activation
(inferredTo)	[Reaction:R-HSA-72670] Formation of eIF2:GDP:eIF2B intermediate