Reactome | D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP

Schema > Reaction > Entries

D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP Show undefined attributes

catalystActivity	[CatalystActivity:10871954] 6-phosphofructokinase activity of PFK tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10871956
displayName	D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
eventOf	[Pathway:R-SPO-70171] Glycolysis - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-70467] D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29512] Fru(6)P [cytosol]
isInDisease	false
isInferred	true
name	D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-30014] F1,6PP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-SPO-70471] alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate - Schizosaccharomyces pombe
regulatedBy	[PositiveRegulation:R-HSA-201329] Positive regulation by 'adenosine 5'-monophosphate [cytosol]' [PositiveRegulation:R-HSA-71505] Positive regulation by 'ADP [cytosol]' [PositiveRegulation:R-HSA-163759] Positive regulation by 'D-Fructose 2,6-bisphosphate [cytosol]' [NegativeRegulation:R-HSA-71507] Negative regulation by 'ATP [cytosol]' [NegativeRegulation:R-HSA-71508] Negative regulation by 'CIT [cytosol]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-70467
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-70171] Glycolysis
(inferredTo)	[Reaction:R-HSA-70467] D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP