Reactome | CDK2 phosphorylates RBBP8

Schema > Reaction > Entries

CDK2 phosphorylates RBBP8 Show undefined attributes

catalystActivity	[CatalystActivity:10888952] protein serine/threonine kinase activity of DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10888954
displayName	CDK2 phosphorylates RBBP8
eventOf	[Pathway:R-SPO-5693607] Processing of DNA double-strand break ends - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-5684140] ATM phosphorylates RBBP8 - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-5684096] CDK2 phosphorylates RBBP8 - Homo sapiens
input	8 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-SPO-5684094] DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm]
isInDisease	false
isInferred	true
name	CDK2 phosphorylates RBBP8
output	8 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-SPO-187952] CCNA:p-T160-CDK2 [nucleoplasm] [Complex:R-SPO-5684095] DNA DSBs:p-MRN:p-S327,T847-RBBP8:p-S1981,Ac-K3016-ATM:KAT5 [nucleoplasm]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-5684096
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-5693607] Processing of DNA double-strand break ends
(precedingEvent)	[Reaction:R-SPO-5684140] ATM phosphorylates RBBP8
(inferredTo)	[Reaction:R-HSA-5684096] CDK2 phosphorylates RBBP8