Reactome | Frs2-mediated activation

Schema > Pathway > Entries

created	[InstanceEdit:10871105] Wright, Adam, 2024-03-08
dbId	10900748
displayName	Frs2-mediated activation
eventOf	[Pathway:R-SPO-169893] Prolonged ERK activation events - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21714] MAPK cascade
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SPO-5674385] p-T,Y MAPKs dimerize - Schizosaccharomyces pombe [BlackBoxEvent:R-SPO-9610166] p-T,Y MAPK dimers translocate to nucleus - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-170968] Frs2-mediated activation - Homo sapiens
isInDisease	false
isInferred	true
name	Frs2-mediated activation
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-170968
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-169893] Prolonged ERK activation events
(inferredTo)	[Pathway:R-HSA-170968] Frs2-mediated activation