Reactome | PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
dbId	10925524
displayName	PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane]
hasComponent	2 × [Complex:R-SCE-350827] Clathrin Triskelion [cytosol] [EntityWithAccessionedSequence:R-SCE-182920] EPS15 [cytosol] [DefinedSet:R-SCE-8862270] FCHO1,2 dimer [cytosol] [GenomeEncodedEntity:R-SCE-8854795] Ghost homologue of AAK1 [cytosol] [GenomeEncodedEntity:R-SCE-8863469] Ghost homologue of NECAPs [cytosol] [GenomeEncodedEntity:R-SCE-8862268] Ghost homologue of SGIP1 [cytosol] [DefinedSet:R-SCE-8862265-5] Homologues of REPS1 [cytosol] [CandidateSet:R-SCE-8862274] ITSNs [cytosol] 3 × [Complex:R-SCE-8856815] p-T156 AP-2 Complex [cytosol] [SimpleEntity:R-ALL-179856] PI(4,5)P2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8856806] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] - Homo sapiens
name	PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1
producedByEvent	[Reaction:R-SCE-8856813] AAK1 phosphorylates AP-2 mu subunit at T156 - Saccharomyces cerevisiae
schemaClass	Complex
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-8856806
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-SCE-8856813] AAK1 phosphorylates AP-2 mu subunit at T156
(inferredTo)	[Complex:R-HSA-8856806] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane]

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