Reactome | ARFGAPs stimulate ARF GTPase activity at the Golgi membrane

Schema > Reaction > Entries

ARFGAPs stimulate ARF GTPase activity at the Golgi membrane Show undefined attributes

catalystActivity	[CatalystActivity:10924574] guanyl-nucleotide exchange factor activity of RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
dbId	10924576
displayName	ARFGAPs stimulate ARF GTPase activity at the Golgi membrane
eventOf	[Pathway:R-SCE-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6811418] ARFGAPs stimulate ARF GTPase activity at the Golgi membrane - Homo sapiens
input	[Complex:R-SCE-6811375] RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane]
isInDisease	false
isInferred	true
name	ARFGAPs stimulate ARF GTPase activity at the Golgi membrane
output	[Complex:R-SCE-6807786] ARF:GDP [cytosol] [DefinedSet:R-SCE-6807832] ARFGAP1,2,3 [cytosol] [EntityWithAccessionedSequence:R-SCE-6807751] GEA2 [cytosol] [Complex:R-SCE-6811377] RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle]
precedingEvent	[Reaction:R-SCE-6811417] ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi - Saccharomyces cerevisiae
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-6811418
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-6811434] COPI-dependent Golgi-to-ER retrograde traffic
(inferredTo)	[Reaction:R-HSA-6811418] ARFGAPs stimulate ARF GTPase activity at the Golgi membrane