Reactome | Rac1:GDP [plasma membrane]

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Rac1:GDP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-8951587] p-VAV family:PIP3:RAC1:GDP [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-9013147] RAC1 GDIs block activation of RAC1 - Rattus norvegicus [Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1 - Rattus norvegicus [BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1 - Rattus norvegicus [Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 - Rattus norvegicus [Reaction:R-RNO-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 - Rattus norvegicus [Reaction:R-RNO-2029451] Activation of RAC1 by VAV - Rattus norvegicus [Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO - Rattus norvegicus [Reaction:R-RNO-8951586] p-VAV family:PIP3 binds RAC1:GDP - Rattus norvegicus [Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1 - Rattus norvegicus [Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex - Rattus norvegicus
created	[InstanceEdit:9619814] Orlic-Milacic, Marija, 2018-09-18
dbId	9619813
displayName	Rac1:GDP [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-29420] GDP [cytosol] [EntityWithAccessionedSequence:R-RNO-205143] Rac1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredFrom	[Complex:R-HSA-9751198] RAC1:6TGTP [plasma membrane] - Homo sapiens [Complex:R-HSA-5674631] RAC1:GDP [plasma membrane] - Homo sapiens
isChimeric	false
name	Rac1:GDP
producedByEvent	[Reaction:R-RNO-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 - Rattus norvegicus [Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9619813

Referrals

(input)	[Reaction:R-RNO-9013147] RAC1 GDIs block activation of RAC1 [Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1 [Reaction:R-RNO-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 [BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1 [BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1 [Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 [Reaction:R-RNO-2029451] Activation of RAC1 by VAV [Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO [Reaction:R-RNO-8951586] p-VAV family:PIP3 binds RAC1:GDP [Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1 [Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex
(output)	[Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity [Reaction:R-RNO-9751201] p-VAV1,2,3 exchange 6TGTP for GDP on RAC1
(inferredTo)	[Complex:R-HSA-9751198] RAC1:6TGTP [plasma membrane] [Complex:R-HSA-5674631] RAC1:GDP [plasma membrane]
(hasComponent)	[Complex:R-RNO-8951587] p-VAV family:PIP3:RAC1:GDP [plasma membrane]

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