Reactome | ATP7A transports cytosolic Cu2+ to extracellular region

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ATP7A transports cytosolic Cu2+ to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10022802] P-type divalent copper transporter activity of ATP7A:PDZD11 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10022804
displayName	ATP7A transports cytosolic Cu2+ to extracellular region
eventOf	[Pathway:R-RNO-936837] Ion transport by P-type ATPases - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-936802] ATP7A transports cytosolic Cu2+ to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-209799] Cu2+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	ATP7A transports cytosolic Cu2+ to extracellular region Copper export from cells by copper-transporting ATPase1
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-437295] Cu2+ [extracellular region] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-936802
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-936837] Ion transport by P-type ATPases
(inferredTo)	[Reaction:R-HSA-936802] ATP7A transports cytosolic Cu2+ to extracellular region

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