Reactome | DENND1s exchange GTP for GDP on RAB35

Schema > Reaction > Entries

DENND1s exchange GTP for GDP on RAB35 Show undefined attributes

catalystActivity	[CatalystActivity:10080488] guanyl-nucleotide exchange factor activity of RAB35 GEFs [cytosol]
category	transition
compartment	[Compartment:262783] recycling endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10080490
displayName	DENND1s exchange GTP for GDP on RAB35
eventOf	[Pathway:R-RNO-8876198] RAB GEFs exchange GTP for GDP on RABs - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8877612] DENND1s exchange GTP for GDP on RAB35 - Homo sapiens
input	[Complex:R-RNO-8877604] GGC-RAB35:GDP:GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
name	DENND1s exchange GTP for GDP on RAB35
output	[DefinedSet:R-RNO-8875305] GDIs,CHMs [cytosol] [SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-RNO-8877601] GGC-RAB35:GTP [recycling endosome membrane]
precedingEvent	[Reaction:R-RNO-8933452] YWHAE dimer binds phosphorylated DENND1 proteins - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8877612
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8876198] RAB GEFs exchange GTP for GDP on RABs
(inferredTo)	[Reaction:R-HSA-8877612] DENND1s exchange GTP for GDP on RAB35