Reactome | DAB2 binds LRP2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10077512
displayName	DAB2 binds LRP2
eventOf	[Pathway:R-RNO-8856825] Cargo recognition for clathrin-mediated endocytosis - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-8867756] CLASP proteins and cargo are recruited to the nascent clathrin-coated pit - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-8863472] DAB2 binds LRP2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-8862456] Dab2 [cytosol] [EntityWithAccessionedSequence:R-RNO-350083] LRP2 [plasma membrane]
isInDisease	false
isInferred	true
name	DAB2 binds LRP2
output	[Complex:R-RNO-8862884] LRP2:DAB2 [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8863472
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-8856825] Cargo recognition for clathrin-mediated endocytosis
(precedingEvent)	[Reaction:R-RNO-8867756] CLASP proteins and cargo are recruited to the nascent clathrin-coated pit
(inferredTo)	[Reaction:R-HSA-8863472] DAB2 binds LRP2