Reactome | dCMP + H2O => dUMP + NH4+

Schema > Reaction > Entries

dCMP + H2O => dUMP + NH4+ Show undefined attributes

catalystActivity	[CatalystActivity:9984551] dCMP deaminase activity of DCTD hexamer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	9984553
displayName	dCMP + H2O => dUMP + NH4+
eventOf	[Pathway:R-RNO-499943] Interconversion of nucleotide di- and triphosphates - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] - Rattus norvegicus [Reaction:R-RNO-73605] dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-73596] dCMP + H2O => dUMP + NH4+ - Homo sapiens
input	[SimpleEntity:R-ALL-109378] dCMP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
name	dCMP + H2O => dUMP + NH4+ deamination of dCMP to form dUMP
output	[SimpleEntity:R-ALL-109382] dUMP [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
precedingEvent	[Reaction:R-RNO-73598] (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) - Rattus norvegicus [Reaction:R-RNO-75125] (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-73596
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-499943] Interconversion of nucleotide di- and triphosphates
(precedingEvent)	[Reaction:R-RNO-73635] dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] [Reaction:R-RNO-73605] dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate
(inferredTo)	[Reaction:R-HSA-73596] dCMP + H2O => dUMP + NH4+