Reactome | RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain

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RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10073612
displayName	RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain
eventOf	[Pathway:R-RNO-6807505] RNA polymerase II transcribes snRNA genes - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-6814549] Pre-snRNA transcript initiation, Integrator binding, LEC binding - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-6810235] RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain - Homo sapiens
input	[Complex:R-RNO-6810221] RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-6810227] RPAP2 [nucleoplasm] [Complex:R-RNO-6814908] RPRD1A,B:RPRD1A,B [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-6814906] Rprd2 [nucleoplasm]
isInDisease	false
isInferred	true
name	RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain
output	[Complex:R-RNO-6810229] RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm]
precedingEvent	[Reaction:R-RNO-6810233] CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6810235
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-6807505] RNA polymerase II transcribes snRNA genes
(precedingEvent)	[BlackBoxEvent:R-RNO-6814549] Pre-snRNA transcript initiation, Integrator binding, LEC binding
(inferredTo)	[Reaction:R-HSA-6810235] RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain

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