Reactome | p-T182 MAPKAPK5 phosphorylates FOXO1

Schema > Reaction > Entries

p-T182 MAPKAPK5 phosphorylates FOXO1 Show undefined attributes

catalystActivity	[CatalystActivity:10063630] protein serine/threonine kinase activity of p-T182-MAPKAPK5 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10063632
displayName	p-T182 MAPKAPK5 phosphorylates FOXO1
eventOf	[Pathway:R-RNO-5687128] MAPK6/MAPK4 signaling - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5692779] p-T182 MAPKAPK5 phosphorylates FOXO1 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-199300] Foxo1 [nucleoplasm]
isInDisease	false
isInferred	true
name	p-T182 MAPKAPK5 phosphorylates FOXO1
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-5692651] phospho-Foxo1 [nucleoplasm]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5692779
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5687128] MAPK6/MAPK4 signaling
(inferredTo)	[Reaction:R-HSA-5692779] p-T182 MAPKAPK5 phosphorylates FOXO1

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