Reactome | NF2 binds PAK1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10059524
displayName	NF2 binds PAK1
eventOf	[Pathway:R-RNO-5627123] RHO GTPases activate PAKs - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5669158] NF2 binds PAK1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-5669168] Nf2 [plasma membrane] [Complex:R-RNO-445002] PAK1 dimer [cytosol]
isInDisease	false
isInferred	true
name	NF2 binds PAK1
output	[Complex:R-RNO-5669157] PAK1:NF2 [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5669158
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-5627123] RHO GTPases activate PAKs
(inferredTo)	[Reaction:R-HSA-5669158] NF2 binds PAK1