Reactome | TP53 Regulates Transcription of Cell Death Genes

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TP53 Regulates Transcription of Cell Death Genes Show undefined attributes

created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10097691
displayName	TP53 Regulates Transcription of Cell Death Genes
eventOf	[Pathway:R-RNO-3700989] Transcriptional Regulation by TP53 - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:139812] regulation of apoptotic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-6803211] TP53 Regulates Transcription of Death Receptors and Ligands - Rattus norvegicus [Pathway:R-RNO-6803204] TP53 Regulates Transcription of Genes Involved in Cytochrome C Release - Rattus norvegicus [Pathway:R-RNO-6803207] TP53 Regulates Transcription of Caspase Activators and Caspases - Rattus norvegicus [Pathway:R-RNO-6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-5633008] TP53 Regulates Transcription of Cell Death Genes - Homo sapiens
isInDisease	false
isInferred	true
name	TP53 Regulates Transcription of Cell Death Genes
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5633008
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3700989] Transcriptional Regulation by TP53
(inferredTo)	[Pathway:R-HSA-5633008] TP53 Regulates Transcription of Cell Death Genes
(hasEncapsulatedEvent)	[Pathway:R-RNO-6791312] TP53 Regulates Transcription of Cell Cycle Genes [Pathway:R-RNO-6804759] Regulation of TP53 Activity through Association with Co-factors

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