Reactome | Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10013839
displayName	Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions
eventOf	[Pathway:R-RNO-420029] Tight junction interactions - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-419981] Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-197845] F11r [plasma membrane] [Complex:R-RNO-419976] Par3:Par6:aPKC complex [cytosol]
isInDisease	false
isInferred	true
name	Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions
output	[Complex:R-RNO-420006] JAM-A:PAR-aPKC complex [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-419981
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-420029] Tight junction interactions
(inferredTo)	[Reaction:R-HSA-419981] Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions

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