Reactome | Signaling by ROBO receptors

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10097927
displayName	Signaling by ROBO receptors
eventOf	[Pathway:R-RNO-422475] Axon guidance - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-8985586] SLIT2:ROBO1 increases RHOA activity - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-376176] Signaling by ROBO receptors - Homo sapiens
isInDisease	false
isInferred	true
name	Signaling by ROBO receptors
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-376176
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-422475] Axon guidance
(inferredTo)	[Pathway:R-HSA-376176] Signaling by ROBO receptors