Reactome | LRP1 (CD91) binds Hemopexin:heme

Schema > Reaction > Entries

LRP1 (CD91) binds Hemopexin:heme Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10042522
displayName	LRP1 (CD91) binds Hemopexin:heme
eventOf	[Pathway:R-RNO-2168880] Scavenging of heme from plasma - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-2230983] LRP1:Hemopexin:heme is endocytosed - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2168897] LRP1 (CD91) binds Hemopexin:heme - Homo sapiens
input	[Complex:R-RNO-2168851] HPX:Hemes [extracellular region] [EntityWithAccessionedSequence:R-RNO-1454844] LRP1 [plasma membrane]
isInDisease	false
isInferred	true
name	LRP1 (CD91) binds Hemopexin:heme
output	[Complex:R-RNO-2168892] LRP1:Hemopexin:heme [plasma membrane]
precedingEvent	[Reaction:R-RNO-2168886] Hemopexin binds Hemes - Rattus norvegicus [Reaction:R-RNO-2168887] Ferriheme is transferred from Albumin to Hemopexin - Rattus norvegicus [Reaction:R-RNO-2168884] Ferriheme is transferred from Methemoglobin to Hemopexin - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2168897
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2168880] Scavenging of heme from plasma
(precedingEvent)	[BlackBoxEvent:R-RNO-2230983] LRP1:Hemopexin:heme is endocytosed
(inferredTo)	[Reaction:R-HSA-2168897] LRP1 (CD91) binds Hemopexin:heme