Reactome | Alpha1-Microglobulin binds heme

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10042468
displayName	Alpha1-Microglobulin binds heme
eventOf	[Pathway:R-RNO-2168880] Scavenging of heme from plasma - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2168888] Alpha1-Microglobulin binds heme - Homo sapiens
input	3 × [EntityWithAccessionedSequence:R-RNO-2168853] AMBP(20-202) [extracellular region] 6 × [SimpleEntity:R-ALL-2168843] heme b [extracellular region]
isInDisease	false
isInferred	true
name	Alpha1-Microglobulin binds heme
output	[Complex:R-RNO-2512834] Alpha1-Microglobulin:heme trimer [extracellular region]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2168888
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-2168880] Scavenging of heme from plasma
(inferredTo)	[Reaction:R-HSA-2168888] Alpha1-Microglobulin binds heme