Reactome | I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol

Schema > Reaction > Entries

I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10036052] inositol monophosphate 3-phosphatase activity of IMPA1/2 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10036054
displayName	I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol
eventOf	[Pathway:R-RNO-1855183] Synthesis of IP2, IP, and Ins in the cytosol - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5678327] MIOX oxidises Ins to GlcA - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1855210] I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1629731] I3P [cytosol]
isInDisease	false
isInferred	true
name	I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol
output	[SimpleEntity:R-ALL-426910] Ins [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-RNO-1855202] I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol - Rattus norvegicus [Reaction:R-RNO-1855178] Glc6P is isomerised to I3P by ISYNA1 in the cytosol - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1855210
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1855183] Synthesis of IP2, IP, and Ins in the cytosol
(precedingEvent)	[Reaction:R-RNO-5678327] MIOX oxidises Ins to GlcA
(inferredTo)	[Reaction:R-HSA-1855210] I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol