Reactome | Innate Immune System

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Innate Immune System Show undefined attributes

created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10095615
displayName	Innate Immune System
eventOf	[TopLevelPathway:R-RNO-168256] Immune System - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:408] innate immune response
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-168898] Toll-like Receptor Cascades - Rattus norvegicus [Pathway:R-RNO-166658] Complement cascade - Rattus norvegicus [Pathway:R-RNO-168643] Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways - Rattus norvegicus [Pathway:R-RNO-879415] Advanced glycosylation endproduct receptor signaling - Rattus norvegicus [Pathway:R-RNO-168928] DDX58/IFIH1-mediated induction of interferon-alpha/beta - Rattus norvegicus [Pathway:R-RNO-1834949] Cytosolic sensors of pathogen-associated DNA - Rattus norvegicus [Pathway:R-RNO-2029480] Fcgamma receptor (FCGR) dependent phagocytosis - Rattus norvegicus [Pathway:R-RNO-2172127] DAP12 interactions - Rattus norvegicus [Pathway:R-RNO-2454202] Fc epsilon receptor (FCERI) signaling - Rattus norvegicus [Pathway:R-RNO-5621481] C-type lectin receptors (CLRs) - Rattus norvegicus [Pathway:R-RNO-6803157] Antimicrobial peptides - Rattus norvegicus [Pathway:R-RNO-6798695] Neutrophil degranulation - Rattus norvegicus [Pathway:R-RNO-1222556] ROS and RNS production in phagocytes - Rattus norvegicus [Pathway:R-RNO-9645460] Alpha-protein kinase 1 signaling pathway - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-168249] Innate Immune System - Homo sapiens
isInDisease	false
isInferred	true
name	Innate Immune System
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-168249
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-RNO-168256] Immune System
(hasEncapsulatedEvent)	[Pathway:R-RNO-5633008] TP53 Regulates Transcription of Cell Death Genes
(inferredTo)	[Pathway:R-HSA-168249] Innate Immune System

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