Reactome | PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane

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PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane Show undefined attributes

catalystActivity	[CatalystActivity:10035245] phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity of PIKFYVE:VAC14:FIG4 [late endosome membrane]
category	transition
compartment	[Compartment:172574] late endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10035247
displayName	PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane
eventOf	[Pathway:R-RNO-1660517] Synthesis of PIPs at the late endosome membrane - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1675795] PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1676020] PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1806289] PI(3,5)P2 [late endosome membrane]
isInDisease	false
isInferred	true
name	PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane
output	[SimpleEntity:R-ALL-29372] Pi [cytosol] [SimpleEntity:R-ALL-1806198] PI3P [late endosome membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1676020
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1660517] Synthesis of PIPs at the late endosome membrane
(precedingEvent)	[Reaction:R-RNO-1675795] PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane
(inferredTo)	[Reaction:R-HSA-1676020] PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane

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