Reactome | PE is hydrolyzed to 1-acyl LPE by PLA2[3]

Schema > Reaction > Entries

PE is hydrolyzed to 1-acyl LPE by PLA2[3] Show undefined attributes

catalystActivity	[CatalystActivity:10032745] phospholipase A2 activity of PLA2(3) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10032747
displayName	PE is hydrolyzed to 1-acyl LPE by PLA2[3]
eventOf	[Pathway:R-RNO-1482839] Acyl chain remodelling of PE - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1482667] 1-acyl LPE is acylated to PE by LPEAT - Rattus norvegicus [Reaction:R-RNO-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
name	PE is hydrolyzed to 1-acyl LPE by PLA2[3]
output	[SimpleEntity:R-ALL-1498738] 1-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-RNO-1482667] 1-acyl LPE is acylated to PE by LPEAT - Rattus norvegicus [Reaction:R-RNO-1482646] 2-acyl LPE is acylated to PE by LPEAT - Rattus norvegicus [Reaction:R-RNO-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1482887
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1482839] Acyl chain remodelling of PE
(precedingEvent)	[Reaction:R-RNO-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C [Reaction:R-RNO-1482667] 1-acyl LPE is acylated to PE by LPEAT
(inferredTo)	[Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3]