Reactome | Activation of ISG15 by UBA7 E1 ligase

Schema > Reaction > Entries

Activation of ISG15 by UBA7 E1 ligase Show undefined attributes

catalystActivity	[CatalystActivity:10028152] ubiquitin-protein transferase activity of UBA7 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10028154
displayName	Activation of ISG15 by UBA7 E1 ligase
eventOf	[Pathway:R-RNO-1169408] ISG15 antiviral mechanism - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1169404] Transfer of ISG15 from E1 to E2 (UBCH8) - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1169397] Activation of ISG15 by UBA7 E1 ligase - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-RNO-936552] Isg15 [cytosol] [EntityWithAccessionedSequence:R-RNO-936550] Uba7 [cytosol]
isInDisease	false
isInferred	true
name	Activation of ISG15 by UBA7 E1 ligase
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-RNO-1169390] ISG15:UBA7 [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1169397
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1169408] ISG15 antiviral mechanism
(precedingEvent)	[Reaction:R-RNO-1169404] Transfer of ISG15 from E1 to E2 (UBCH8)
(inferredTo)	[Reaction:R-HSA-1169397] Activation of ISG15 by UBA7 E1 ligase