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Go!
Schema
>
Complex
>
Entries
p21 RAS:GDP [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-RNO-9632908] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] - Rattus norvegicus
consumedByEvent
[Reaction:R-RNO-5654426] Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-8941613] Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-5654663] Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-8941618] Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-5654618] Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-5654402] Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-1168636] p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP - Rattus norvegicus
[Reaction:R-RNO-186834] SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) - Rattus norvegicus
[Reaction:R-RNO-9632906] PRKCZ recruits RAS in response to estrogen stimulation - Rattus norvegicus
[Reaction:R-RNO-5654392] Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-8941623] Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras - Rattus norvegicus
[Reaction:R-RNO-8941628] Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-5654413] Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-210977] Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) - Rattus norvegicus
[Reaction:R-RNO-177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) - Rattus norvegicus
[Reaction:R-RNO-177945] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) - Rattus norvegicus
[Reaction:R-RNO-1306972] RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers - Rattus norvegicus
[Reaction:R-RNO-9649735] Intrinsic nucleotide exchange on RAS - Rattus norvegicus
[Reaction:R-RNO-9607304] SOS1-mediated nucleotide exchange of RAS downstream of FLT3 - Rattus norvegicus
[Reaction:R-RNO-5672965] RAS GEFs promote RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-8851899] RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET - Rattus norvegicus
[Reaction:R-RNO-8851877] RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET - Rattus norvegicus
[Reaction:R-RNO-1250383] RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 - Rattus norvegicus
[Reaction:R-RNO-2179407] SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) - Rattus norvegicus
[Reaction:R-RNO-5654600] Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-1433471] Activation of RAS by p-KIT bound SOS1 - Rattus norvegicus
[Reaction:R-RNO-5654647] Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange - Rattus norvegicus
[Reaction:R-RNO-2424477] SOS mediated nucleotide exchange of RAS (SHC) - Rattus norvegicus
[Reaction:R-RNO-8851827] RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 - Rattus norvegicus
created
[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId
9997139
displayName
p21 RAS:GDP [plasma membrane]
hasComponent
[SimpleEntity:R-ALL-29420] GDP [cytosol]
[DefinedSet:R-RNO-9649715] mature p21 RAS [plasma membrane]
inDisease
false
inferredFrom
[Complex:R-HSA-109796] p21 RAS:GDP [plasma membrane] - Homo sapiens
name
p21 RAS:GDP
producedByEvent
[Reaction:R-RNO-8981353] RASA1 stimulates RAS GTPase activity - Rattus norvegicus
[Reaction:R-RNO-5658231] RAS GAPs stimulate RAS GTPase activity - Rattus norvegicus
[Reaction:R-RNO-9649736] RAS intrinsic GTPase activity hydrolyzes GTP to GDP - Rattus norvegicus
[Reaction:R-RNO-9649733] mature p21 RAS binds GDP - Rattus norvegicus
schemaClass
Complex
species
[Species:48895] Rattus norvegicus
stId
R-RNO-109796
summation
[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Referrals
(input)
[Reaction:R-RNO-5654426] Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-8941613] Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange
[Reaction:R-RNO-5654663] Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-8941618] Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange
[Reaction:R-RNO-5654618] Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-5654402] Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-2179407] SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated)
[Reaction:R-RNO-1168636] p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP
[Reaction:R-RNO-186834] SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS)
[Reaction:R-RNO-9632906] PRKCZ recruits RAS in response to estrogen stimulation
[Reaction:R-RNO-5654600] Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-5654392] Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-8941623] Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange
[Reaction:R-RNO-392054] NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras
[Reaction:R-RNO-1433471] Activation of RAS by p-KIT bound SOS1
[Reaction:R-RNO-8941628] Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange
[Reaction:R-RNO-5654413] Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-5654647] Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange
[Reaction:R-RNO-210977] Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos)
[Reaction:R-RNO-2424477] SOS mediated nucleotide exchange of RAS (SHC)
[Reaction:R-RNO-177938] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1)
[Reaction:R-RNO-177945] SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1)
[Reaction:R-RNO-1306972] RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers
[Reaction:R-RNO-9649735] Intrinsic nucleotide exchange on RAS
[Reaction:R-RNO-9607304] SOS1-mediated nucleotide exchange of RAS downstream of FLT3
[Reaction:R-RNO-5672965] RAS GEFs promote RAS nucleotide exchange
[Reaction:R-RNO-8851899] RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET
[Reaction:R-RNO-8851827] RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1
[Reaction:R-RNO-8851877] RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET
[Reaction:R-RNO-1250383] RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4
(hasComponent)
[Complex:R-RNO-9632908] PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane]
(output)
[Reaction:R-RNO-8981353] RASA1 stimulates RAS GTPase activity
[Reaction:R-RNO-5658231] RAS GAPs stimulate RAS GTPase activity
[Reaction:R-RNO-9649736] RAS intrinsic GTPase activity hydrolyzes GTP to GDP
[Reaction:R-RNO-9649733] mature p21 RAS binds GDP
(inferredTo)
[Complex:R-HSA-109796] p21 RAS:GDP [plasma membrane]
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