Reactome | NNT dimer transfers proton from NADPH to NAD+

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NNT dimer transfers proton from NADPH to NAD+ Show undefined attributes

catalystActivity	[CatalystActivity:10937518] NAD(P)+ transhydrogenase activity of NNT dimer [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5462] mitochondrion
created	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
dbId	10937520
displayName	NNT dimer transfers proton from NADPH to NAD+
eventOf	[Pathway:R-PFA-71403] Citric acid cycle (TCA cycle) - Plasmodium falciparum
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-450971] NNT dimer transfers proton from NADPH to NAD+ - Homo sapiens
input	[SimpleEntity:R-ALL-163953] H+ [mitochondrial intermembrane space] [SimpleEntity:R-ALL-113526] NAD+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix]
isInDisease	false
isInferred	true
name	NNT dimer transfers proton from NADPH to NAD+ H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)
output	[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29362] NADH [mitochondrial matrix] [SimpleEntity:R-ALL-113563] NADP+ [mitochondrial matrix]
precedingEvent	[Reaction:R-PFA-450984] IDH2 dimer decarboxylates isocitrate - Plasmodium falciparum
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-450971
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-71403] Citric acid cycle (TCA cycle)
(inferredTo)	[Reaction:R-HSA-450971] NNT dimer transfers proton from NADPH to NAD+

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