Reactome | Mapk1 (Erk2) phosphorylates ERF

Schema > Reaction > Entries

authored	[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
catalystActivity	[CatalystActivity:3245929] protein serine/threonine kinase activity of p-T183,Y185-Mapk1 dimer [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3245927] Orlic-Milacic, M, 2013-03-28
dbId	3245934
displayName	Mapk1 (Erk2) phosphorylates ERF
edited	[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15 [InstanceEdit:4542306] Matthews, L, 2013-07-15
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-2534321] ERF [nucleoplasm]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3209175] ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Mapk1 (Erk2) phosphorylates ERF
orthologousEvent	[Reaction:R-HSA-3209160] Activated ERKs phosphorylate ERF - Homo sapiens
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3209166] p-T526-ERF [nucleoplasm]
releaseDate	2013-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48895] Rattus norvegicus
stId	R-NUL-3245934
summation	[Summation:3245931] Recombinant rat Mapk1 (Erk2) phosphorylates recombinant huma...

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