Reactome | Gck gene expression is inhibited by Foxo1, Sin3a and Hdac

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9625975] Orlic-Milacic, Marija, 2018-10-23
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9625108] Orlic-Milacic, Marija, 2018-10-18
dbId	9625102
displayName	Gck gene expression is inhibited by Foxo1, Sin3a and Hdac
edited	[InstanceEdit:9627016] Orlic-Milacic, Marija, 2018-10-31
input	[EntityWithAccessionedSequence:R-MMU-9625110] Gck gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9625123] Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Gck gene expression is inhibited by Foxo1, Sin3a and Hdac
orthologousEvent	[BlackBoxEvent:R-HSA-9625124] GCK gene expression is inhibited by FOXO1, SIN3A and HDACs - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9625144] Gck [cytosol]
regulatedBy	[NegativeGeneExpressionRegulation:9625142] Negative gene expression regulation by 'Foxo1:Sin3a:Hdac1,Hdac2 dimers:Gck gene [nucleoplasm]'
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9626980] Donlon, Timothy, 2018-10-23
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9625102
summation	[Summation:9625120] In mouse hepatocytes, Foxo1, together with Sin3a and histone...

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