Reactome | Mecp2 is phosphorylated at S421

Schema > Reaction > Entries

Mecp2 is phosphorylated at S421 Show undefined attributes

authored	[InstanceEdit:9024208] Orlic-Milacic, Marija, 2017-10-02
catalystActivity	[CatalystActivity:9007028] calmodulin-dependent protein kinase activity of Active CaMK IV,(CaMK II) [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007014] Orlic-Milacic, Marija, 2017-05-25
dbId	9007015
displayName	Mecp2 is phosphorylated at S421
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [CandidateSet:R-MMU-9006015] Mecp2 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9006983] Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function [LiteratureReference:9017356] Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Mecp2 is phosphorylated at S421
orthologousEvent	[Reaction:R-HSA-9006992] MECP2 is phosphorylated at S423 - Homo sapiens
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [CandidateSet:R-MMU-9007023] p-S421-Mecp2 [nucleoplasm]
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608114] Christodoulou, John, 2018-08-07 [InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9007015
summation	[Summation:9023734] Mouse calmodulin-activated kinase CaMK IV, and possibly CaMK...