Reactome | G beta-gamma complex and PIP3 recruit BTK to membrane

Schema > Reaction > Entries

G beta-gamma complex and PIP3 recruit BTK to membrane Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9965675
displayName	G beta-gamma complex and PIP3 recruit BTK to membrane
eventOf	[Pathway:R-MMU-8964315] G beta:gamma signalling through BTK - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8964271] BTK in PIP3:BTK:G beta-gamma complex is activated - Mus musculus
inferredFrom	[Reaction:R-HSA-8964241] G beta-gamma complex and PIP3 recruit BTK to membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-2685636] Btk [cytosol] [Complex:R-MMU-167434] G-protein beta-gamma complex [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane]
isInDisease	false
isInferred	true
name	G beta-gamma complex and PIP3 recruit BTK to membrane
output	[Complex:R-MMU-8964249] PIP3:BTK:G-protein beta-gamma complex [plasma membrane]
precedingEvent	[Reaction:R-MMU-392202] Dissociation of the P2Y purinoceptor 12:Gi complex - Mus musculus [Reaction:R-MMU-418576] Dissociation of the P2Y purinoceptor 1:Gq complex - Mus musculus [Reaction:R-MMU-397891] Thrombin-activated PARs:G12/13 (active) dissociate - Mus musculus [Reaction:R-MMU-397835] Thrombin-activated PARs:Gq (active) dissociate - Mus musculus [Reaction:R-MMU-749452] The Ligand:GPCR:Gq complex dissociates - Mus musculus [Reaction:R-MMU-749454] The Ligand:GPCR:Gi complex dissociates - Mus musculus [Reaction:R-MMU-751024] The Ligand:GPCR:Gz complex dissociates - Mus musculus [Reaction:R-MMU-751019] The Ligand:GPCR:G12/13 complex dissociates - Mus musculus [Reaction:R-MMU-3965447] G-protein subunits dissociate from WNT:FZD complex - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8964241
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8964315] G beta:gamma signalling through BTK
(precedingEvent)	[Reaction:R-MMU-8964271] BTK in PIP3:BTK:G beta-gamma complex is activated
(inferredTo)	[Reaction:R-HSA-8964241] G beta-gamma complex and PIP3 recruit BTK to membrane