Reactome | Eif4g1 [cytosol]

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Eif4g1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] - Mus musculus [Complex:R-MMU-429977] Translatable mRNA Complex [cytosol] - Mus musculus [Complex:R-MMU-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] - Mus musculus [Complex:R-MMU-927845] mRNA Cleaved by SMG6 [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-165766] Phosphorylation and activation of eIF4G by activated S6K1 - Mus musculus [Reaction:R-MMU-72631] Formation of the cap-binding eIF4F complex - Mus musculus [Reaction:R-MMU-450551] AUF1 binds translation and heat shock proteins - Mus musculus
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9867600
displayName	Eif4g1 [cytosol]
endCoordinate	1599
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol] - Homo sapiens
memberOf	[DefinedSet:R-MMU-1678828] EIF4G [cytosol] - Mus musculus
name	Eif4g1 EIF4G1 Q6NZJ6
producedByEvent	[BlackBoxEvent:R-MMU-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex - Mus musculus [Reaction:R-MMU-429992] PARN deadenylates mRNA - Mus musculus [Reaction:R-MMU-429955] CCR4-NOT complex deadenylates mRNA - Mus musculus [Reaction:R-MMU-72619] eIF2:GTP is hydrolyzed, eIFs are released - Mus musculus
referenceEntity	[ReferenceGeneProduct:232523] UniProt:Q6NZJ6 Eif4g1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-72584
startCoordinate	1

Referrals

(input)	[Reaction:R-MMU-450551] AUF1 binds translation and heat shock proteins [Reaction:R-MMU-72631] Formation of the cap-binding eIF4F complex [Reaction:R-MMU-165766] Phosphorylation and activation of eIF4G by activated S6K1
(hasComponent)	[Complex:R-MMU-450623] AUF1 Complexed with Translation and Heat Shock Proteins [cytosol] [Complex:R-MMU-927845] mRNA Cleaved by SMG6 [cytosol] [Complex:R-MMU-927743] mRNA Complex with a Premature Termination Codon Preceding an Exon Junction [cytosol] [Complex:R-MMU-927823] mRNA Complex with a Premature Termination Codon Not Preceding an Exon Junction [cytosol] [Complex:R-MMU-429989] Partially Deadenylated mRNA Complex [cytosol] [Complex:R-MMU-429977] Translatable mRNA Complex [cytosol] [Complex:R-MMU-72587] eIF4F [cytosol]
(output)	[BlackBoxEvent:R-MMU-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex [Reaction:R-MMU-429992] PARN deadenylates mRNA [Reaction:R-MMU-429955] CCR4-NOT complex deadenylates mRNA [Reaction:R-MMU-72619] eIF2:GTP is hydrolyzed, eIFs are released
(hasMember)	[DefinedSet:R-MMU-1678828] EIF4G [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72584] EIF4G1 [cytosol]

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